03-10-2013 дата публикации
Номер: US20130255355A1
Автор:
Belcher William Randall,
CLAPP Mannie Lee,
DATTA Saswati,
EL-NOKALY Magda,
III Richard,
MURAWSKI Sandra Lou,
Page Steven Hardy,
Paldey Sohini,
TWEDDELL,
WARNER Ronald R.,
WONG Louis Fay
Method of evaluating a product by applying a substance to the surface of an artificial substrate to form a substance-coated surface and performing an analysis of the substance-coated surface. The surface of the substrate may have one or more of the following properties: a total surface energy of from about 15 mJ/mto about 50 mJ/m, a polar component of the total surface energy of from about 0 mJ/mto about 15 mJ/m, and a zeta-potential at a pH of about 5.0 of from about −30 mV to about 30 mV. 1. A method of product evaluation comprising the steps of:a) providing an artificial first substrate having a physical property representative of mammalian keratinous tissue;b) providing a second substrate;c) contacting at least one of the substrates to an instrument capable of measuring frictional force;d) bringing the first substrate into contact with the second substrate;e) moving the first substrate with respect to the second substrate in a controlled manner while maintaining substantially continuous contact between the first substrate and the second substrate; andf) measuring the frictional force generated by the movement of the first substrate relative to the second substrate.2. The method of claim 1 , wherein a substance is applied to at least one of the substrates.3. The method of claim 1 , wherein at least one of the substrates is rinsed at least once.4. The method of claim 1 , wherein the movement of the first substrate with respect to the second substrate is repeated at least once.5. The method of claim 1 , wherein the artificial first substrate is comprised of polyurethane claim 1 , polydimethylsiloxane claim 1 , linear polyethylene claim 1 , isotactic polypropylene claim 1 , polystyrene claim 1 , polyamide claim 1 , and combinations thereof.6. The method of claim 1 , wherein the artificial first substrate is textured.7. The method of claim 6 , wherein the texture of the artificial first substrate mimics mammalian keratinous tissue.8. The method of claim 1 , wherein ...
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