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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 6. Отображено 6.
25-07-2023 дата публикации

Extracellular vesicle co-delivery system for tumor treatment and application of extracellular vesicle co-delivery system

Номер: CN116479043A
Автор: YANG GUODONG, XING YUQI, ZHAO JING, WEI MENGYING, JI PANPAN, SUN WENQI
Принадлежит:

The invention belongs to the technical field of antitumor drug research, and particularly relates to an extracellular vesicle co-delivery system for tumor treatment and application of the extracellular vesicle co-delivery system. The co-delivery system is obtained by encapsulating effector molecule mRNA related to a cell death mode in an extracellular vesicle membrane, incorporating a substance capable of inducing generation of singlet oxygen into the extracellular vesicle membrane and loading a targeting peptide or antibody on the surface of the extracellular vesicle. According to the extracellular vesicle co-delivery system provided by the invention, the effector molecule mRNA is translated and inhibited by the optimized puromycin in the extracellular vesicle donor cells, so that the mRNA is promoted to be encapsulated into the extracellular vesicles; in donor cells, along with dilution of puromycin concentration and treatment of puromycin inactivation through a substance capable of generating ...

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Номер записи: 1
23-05-2023 дата публикации

Monitoring data display method, central station and monitoring system

Номер: CN116138732A
Автор: WEI MENGYING
Принадлежит:

The invention relates to the technical field of medical equipment, in particular to a monitoring data display method, a central station and a monitoring system.The display method comprises the steps that a central monitoring interface is displayed, the central monitoring interface comprises a monitoring data display area, and the monitoring data display area is used for displaying real-time monitoring data of one or more monitoring objects; in response to a setting operation on the target monitoring data display area, displaying an interface setting area and an interface preview area on the central monitoring interface; receiving setting of a user on the real-time monitoring data in the interface setting area, and displaying a setting result in the interface preview area; and adjusting the display of the real-time monitoring data in the monitoring data display area according to the setting result. According to the method, the interface setting area and the interface preview area are displayed ...

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Номер записи: 2
14-07-2023 дата публикации

Fluorescence-modified semeglutide derivative as well as preparation method and application thereof

Номер: CN116425858A
Автор: LIU XIANGRUI, ZHOU TIANHUA, WEI MENGYING, LI QI, ZHOU QUAN, WANG JIAFENG, XIE SHANSHAN
Принадлежит:

The invention discloses a fluorescence modified semeglutide derivative and a preparation method thereof. The semeglutide derivative is obtained by covalent coupling of semeglutide and an activated fluorescent molecule. The fluorescence-modified semeglutide derivative has similar absorption characteristics with a semeglutide prototype drug in a living body, so that the content of the semeglutide can be obtained by detecting the intensity of a fluorescence signal by taking the semeglutide derivative as a fluorescence molecular probe. The monitoring method is suitable for in-vivo quantitative analysis and analysis of complex biological samples, the quantitative linear range in analysis of the complex biological samples is wide, complex sample pretreatment is not needed, only a microplate reader is needed for fluorescence detection during detection, operation is easy, and the detection speed is high.

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Номер записи: 3
07-04-2023 дата публикации

Reactor waste heat removal system

Номер: CN115938621A
Автор: YANG HONGYI, CHEN ZHENJIA, WEI MENGYING, HOU BIN, HUANG YUANBIN, ZHUANG YI, XIAO CHANGZHI, QIAO PENGRUI, YE YUANWU, ZHU LINA, ZHOU LIJUN, XU SHUMAO, CAO YONGGANG, WANG LIXIA
Принадлежит:

The embodiment of the invention provides a reactor residual heat removal system, which comprises a first barrel arranged in a reactor container and arranged on the outer side of a reactor core, a second barrel arranged on the top of the first barrel, a first opening and a second opening located below the first opening, and a third barrel arranged in the reactor container and arranged on the outer side of the reactor core, the second barrel is arranged in the reactor container and is arranged on the outer side of the first barrel, and a first gap is formed between the second barrel and the reactor container; the heat exchange module is used for cooling a coolant in the reactor core, and the heat exchange module is connected with the second opening; the circulating module is connected with the heat exchange module; the shell is arranged on the outer side of the reactor container, a second gap is formed between the shell and the reactor container, and the second gap is communicated with the ...

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Номер записи: 4
12-05-2023 дата публикации

Monitoring method, central station and central monitoring system

Номер: CN116099080A
Автор: WEI MENGYING
Принадлежит:

The invention relates to the technical field of medical equipment, in particular to a monitoring method, a central station and a central monitoring system.The monitoring method comprises the steps that physiological parameter data and infusion data of at least one target object at the same time are obtained; the physiological parameter data and the infusion data are displayed in corresponding parameter display areas in a monitoring main interface so as to perform conjoint analysis on vital sign changes of the target objects, the monitoring main interface comprises a plurality of parameter display areas, and each parameter display area corresponds to each target object; receiving the operation object, performing conjoint analysis, adjusting and setting the infusion data, and displaying the infusion data after adjustment and setting in the parameter display area. According to the monitoring method, the physiological parameter data and the infusion data are jointly observed, medical staff ...

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Номер записи: 5
22-08-2023 дата публикации

Engineered exosome targeting liver antagonism PCSK9 and specifically binding to LDL-C as well as construction method and application of engineered exosome

Номер: CN116622639A
Автор: YUAN LIJUN, WANG CHEN, YANG GUODONG, WEI MENGYING, LI ZHELONG, ZHANG LIANG, SUN WENQI
Принадлежит:

The invention provides an engineered exosome targeting liver antagonism PCSK9 and specifically combined with LDL-C as well as a construction method and application of the engineered exosome, and belongs to the technical field of exosomes. According to the invention, transmembrane protein PTGFRN is modified, and an L3-L7 section PTGFRN sequence containing LDLR is subjected to fusion expression outside a membrane, so that LDL-C can be specifically combined; meanwhile, a PCSK9 inhibiting drug Inclisiran is connected with the surface of the exosome. The engineered exosome has the dual effects of antagonizing PCSK9 and promoting LDL-C degradation at the same time, not only can efficiently target the liver and inhibit expression of PCSK9 by liver cells, but also can be specifically combined with LDL-C to be degraded in the liver, a brand-new way is provided for reducing the blood fat content, and the engineered exosome has wide application value. Meanwhile, the engineered exosome provided by ...

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Номер записи: 6