BIODETEKTIONSINSTRUMENT UND AUSWERTUNGSVERFAHREN

System and method for deriving material change attributes from curated and analyzed data signals over time to predict future changes in conventional predictors

A system and method for deriving a material change attribute over time to predict a future change in at least one predictor, the method comprising: collecting precursor data from at least one data source; processing the precursor data by assessing at least one characteristic of the precursor data; generating at least one material change signal from the processed precursor data; evaluating the material change signal to determine the signal's value in predicting future changes in the predictor and, optionally, reverting to the collection and processing steps above to process additional precursor data; and generating at least one the material change attribute from the evaluated material change signal.

SYSTEM AND METHOD FOR DERIVING MATERIAL CHANGE ATTRIBUTES FROM CURATED AND ANALYZED DATA SIGNALS OVER TIME TO PREDICT FUTURE CHANGES IN CONVENTIONAL PREDICTORS

A system and method for deriving a material change attribute over time to predict a future change in at least one predictor, the method comprising: collecting precursor data from at least one data source; processing the precursor data by assessing at least one characteristic of the precursor data; generating at least one material change signal from the processed precursor data; evaluating the material change signal to determine the signal's value in predicting future changes in the predictor and, optionally, reverting to the collection and processing steps above to process additional precursor data; and generating at least one the material change attribute from the evaluated material change signal.

STABILISIERTE GABELSTROMVERSORGUNG

SYSTEM AND METHOD FOR DERIVING MATERIAL CHANGE ATTRIBUTES FROM CURATED AND ANALYZED DATA SIGNALS OVER TIME TO PREDICT FUTURE CHANGES IN CONVENTIONAL PREDICTORS

FILTER AND WIRE WITH DISTAL ISOLATION

A wire may be configured to provide distal isolation from proximal movement, and a filter may be deployed at or near a distal portion of the wire. A filter may be deployed on a spinner tube that is rotatably disposed about a distal portion of the wire. Axial movement of the filter wire may be at least partially absorbed by the spinner tube. A telescoping wire may include a solid proximal wire section, a solid distal wire section and a joining section that is disposed between the solid proximal wire section and the solid distal wire section. The joining section may translate rotational movement between the distal and proximal sections.

System and method for deriving material change attributes from curated and analyzed data signals over time to predict future changes in conventional predictors

A system and method for deriving a material change attribute over time to predict a future change in at least one predictor, the method comprising: collecting precursor data from at least one data source; processing the precursor data by assessing at least one characteristic of the precursor data; generating at least one material change signal from the processed precursor data; evaluating the material change signal to determine the signal's value in predicting future changes in the predictor and, optionally, reverting to the collection and processing steps above to process additional precursor data; and generating at least one the material change attribute from the evaluated material change signal.

Loading Ramp Assembly For Vehicle

Egg hatching and larvae separation devices and methods

A device including a fluid-tight container, wherein the fluid-tight container includes a base having a first portion and a second portion; at least one wall enclosing the base and coupled to the base to form a fluid-tight seal; wherein the first portion of the base comprises a first color and defines a recess; and wherein the second portion of the base comprises a second color darker than the first color.

BIOSENSOR MIT AUSFALLGESICHERTEM BETRIEBSVERFAHREN ZUR VERMEIDUNG VON FALSCHEN ANZEIGEN

STABILISIERTE GABELSTROMVERSORGUNG

BIOSENSOR MIT EINER VORRICHTUNG UND DEREN VERFAHREN ZUR SCHÄTZUNG DER UMGEBUNGSTEMPERATUR

BIODETEKTIONSINSTRUMENT UND AUSWERTUNGSVERFAHREN

BIOSENSOR MIT EINEM STECKBAREN SPEICHERSCHLÜSSEL

BIOMESSER ZUR FESTSTELLUNG KORREKTER ELEKTRODENKOPPLUNG UND ZUR UNTERSCHEIDUNG ZWISCHEN PROBE- UND REFERENZSTREIFEN

EGG HATCHING AND LARVAE SEPARATION DEVICES AND METHODS

FILTER AND WIRE WITH DISTAL ISOLATION

A wire may be configured to provide distal isolation from proximal movement, and a filter may be deployed at or near a distal portion of the wire. A filter may be deployed on a spinner tube that is rotatably disposed about a distal portion of the wire. Axial movement of the filter wire may be at least partially absorbed by the spinner tube. A telescoping wire may include a solid proximal wire section, a solid distal wire section and a joining section that is disposed between the solid proximal wire section and the solid distal wire section. The joining section may translate rotational movement between the distal and proximal sections.

EMBOLIC PROTECTION FILTERS, FILTER MEMBRANES, AND METHODS FOR MAKING AND USING THE SAME

Embolic protection filters, filter membranes, and methods for making and using the same. An example embolic protection filter may include an elongate shaft having a proximal region and a distal region. A filter frame may be to the distal region. A filter membrane may be attached to the filter frame. The filter membrane may have a plurality of apertures formed therein. The filter membrane may include a polymer having a bulk portion and a surface portion. The surface portion may include a surface modification.

SYSTEM AND METHOD FOR DERIVING MATERIAL CHANGE ATTRIBUTES FROM CURATED AND ANALYZED DATA SIGNALS OVER TIME TO PREDICT FUTURE CHANGES IN CONVENTIONAL PREDICTORS

A system and method for deriving a material change attribute over time to predict a future change in at least one predictor, the method comprising: collecting precursor data from at least one data source; processing the precursor data by assessing at least one characteristic of the precursor data; generating at least one material change signal from the processed precursor data; evaluating the material change signal to determine the signal's value in predicting future changes in the predictor and, optionally, reverting to the collection and processing steps above to process additional precursor data; and generating at least one the material change attribute from the evaluated material change signal.

FABRICATING SOLID OXIDE FUEL CELLS

A method for making a solid oxide fuel cell component includes depositing a cathode material directly onto a metallic interconnect. The interconnect may comprise stainless steel or another suitable metal. The cathode material may comprise a ceramic. Examples of cathode materials are yttria-stabilized zirconia (YSZ) and mixtures of YSZ with other ceramics such as lanthanum strontium manganate. The cathode material may be deposited by plasma spraying. A pore former may be plasma sprayed together with the cathode material to provide a porous cathode. Electrolyte and anode materials may be deposited on the cathode material also by plasma spraying. Plasma conditions may be selected to provide a dense electrolyte layer.

EGG HATCHING AND LARVAE SEPARATION DEVICES AND METHODS

A device including a fluid-tight container, wherein the fluid-tight container includes a base having a first portion and a second portion; at least one wall enclosing the base and coupled to the base to form a fluid-tight seal; wherein the first portion of the base comprises a first color and defines a recess; and wherein the second portion of the base comprises a second color darker than the first color.

SYSTEMS AND METHODS FOR AUTOMATED AQUATIC INSECT REARING

An example system for automated aquatic insect rearing includes a frame; at least one trough having a drain, the trough supported by the frame; a drain valve coupled to the drain; a lid coupleable to the at least one trough to cover the trough, the lid defining at least one opening; a fluid supply tube connectable to a fluid supply, the fluid supply tube routed to provide fluid to the at least one trough; a fill valve coupled to the fluid supply tube, the fill valve positioned and configured to regulate a flow of fluid into the at least one trough; a fill pump coupled to the at least one fluid supply tube and coupleable to the fluid supply to pump fluid from the fluid supply through the at least one supply tube; at least one feeding mechanism to dispense food into the at least one trough; and at least one fluid level sensor positioned to detect a fluid level within the at least one trough. 1. A system comprising:a frame;at least one trough having a drain, the trough supported by the frame;a drain valve coupled to the drain;a lid coupleable to the at least one trough to cover the trough, the lid defining at least one opening;a fluid supply tube connectable to a fluid supply, the fluid supply tube routed to provide fluid to the at least one trough;a fill valve coupled to the fluid supply tube, the fill valve positioned and configured to regulate a flow of fluid into the at least one trough;a fill pump coupled to the at least one fluid supply tube and coupleable to the fluid supply to pump fluid from the fluid supply through the at least one supply tube;at least one feeding mechanism to dispense food into the at least one trough; andat least one fluid level sensor positioned to detect a fluid level within the at least one trough.2. The system of claim 1 , further comprising one or more computing devices in communication with the heating element claim 1 , the fill pump claim 1 , the at least one feed mechanism claim 1 , and the at least one sensor claim 1 , the one or ...

Surgical instruments with electrodes

A surgical stapling assembly is configured to be used to form a tissue seal having an arcuate portion. The surgical stapling assembly comprises an end-effector extending from the distal end of the shaft. The end-effector comprises a first portion and a second portion. The first portion comprises a first face at least partially surrounding the aperture, a staple cavity defined in the first face, a staple removably positioned within the staple cavity, and a first electrode positioned one of on and proximate to the first face. The second portion comprises a second face, an anvil pocket defined in the second face, and a second electrode positioned one of on and proximate to the second face, and a second electrode. The first electrode and the second electrode each comprise an arcuate portion. The first electrode has a different polarity than the second electrode.

ELECTROSURGICAL CUTTING AND SEALING INSTRUMENT

A surgical instrument for supplying energy to tissue can comprise a jaw member comprising an electrode, wherein the electrode is configured to supply energy from a power source to captured tissue. The surgical instrument comprises a tissue-cutting element to transect the captured tissue. The rate of distal translation of the tissue-cutting element during the operational stroke may be regulated by an electromagnetic brake. 1. An electrosurgical instrument , comprising:a handle;an elongate shaft extending distally from the handle;a trigger moveable between a first position and a second position;an electromagnetic brake; and a first jaw member;', 'a second jaw member, wherein the first jaw member is movable relative to the second jaw member between an open and a closed position; and', 'a tissue-cutting element configured to translate with respect to the first jaw and the second jaw;, 'an end effector coupled to the distal end of the elongate shaft, comprisingan axially moveable cutting member configured to open and close the jaws, the tissue-cutting element positioned at a distal end of the axially movable member; andan electrode.2. The electrosurgical instrument of claim 1 , wherein the electromagnetic brake is configured to selectably engage the trigger.3. The electrosurgical instrument of claim 2 , wherein the electromagnetic comprises a brake pad.4. The electrosurgical instrument of claim 3 , wherein electromagnetic brake comprises a solenoid coupled to the brake pad.5. The electrosurgical instrument of claim 3 , wherein the brake pad comprises at least one pad ridge claim 3 , and wherein at least one of the trigger and the axially moveable cutting member comprises a brake pad engagement portion.6. The electrosurgical instrument of claim 5 , wherein the brake pad engagement portion comprises a plurality of troughs.7. The electrosurgical instrument of claim 6 , wherein the at least one pad ridge is configured to engage at least one trough.8. The electrosurgical ...

Two-Part Electrotransport Device

A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence. 1. A corrosion-resistant electrotransport drug delivery device comprising an electrical module and a reservoir module , the electrical module and the reservoir module configured to be combined to form a unitary , activated drug delivery device prior to use , wherein the device resists corrosion by electrically isolating a circuitry in the electrical module from a power source , the circuitry;', 'an electrical output adapted to connect the circuitry to an input connector on the reservoir module when the electrical module is combined with the reservoir module; and', 'at least two power-on contacts between the circuitry and a battery;', 'wherein the battery, is isolated from the circuitry by the power-on contacts while at least one of the power-on contacts remains open, and the battery is connected into the circuitry when all of the power-on contacts are closed by battery contact actuators on the reservoir module when the electrical module and the reservoir module are combined; and, 'further wherein the electrical module comprises an electrical input adapted to electrically connect the circuitry in the electrical module to at least a pair of active electrodes in the reservoir module when the electrical module ...

CHANGING THE LOCATION OF A BUFFER BAY IN A NETLIST

In an embodiment, a buffer bay is represented with a moveable object that has a location within a unit in a netlist. The location of the moveable object that represents the buffer bay is changed to a new location in the netlist if changing the location improves placement within the unit. In an embodiment, a net weight of a net that connects the moveable object to an artificial pin is considered in determining whether to change the location to the new location. In an embodiment a bounding area that encompasses the location is considered in determining whether to change the location to the new location. 1. A method comprising:representing a buffer bay with a moveable object having a location within a unit in a netlist; andchanging the location of the moveable object that represents the buffer bay to a new location in the netlist if changing the location improves placement within the unit.2. The method of claim 1 , wherein the changing the location if the changing the location improves placement within the unit comprises:considering a net weight in determining whether to change the location to the new location.3. The method of claim 2 , wherein the considering the net weight in determining whether to change the location to the new location further comprises:creating an artificial pin connected to the moveable object via a net.4. The method of claim 3 , wherein the considering the net weight in determining whether to change the location to the new location further comprises:assigning the net weight to the net that connects the artificial pin to the moveable object.5. The method of claim 3 , wherein the net weight that is a higher priority than net weights of other nets increases a probability that the new location of the moveable object is constrained to an area within a threshold radius from the artificial pin.6. The method of claim 3 , further comprising:removing the artificial pin after the changing the location.7. The method of claim 1 , wherein the changing the ...

Iimplementing z directional macro port assignment

A method, system and computer program product are provided for implementing an enhanced Z-directional macro port assignment or three-dimensional port creation for random logic macros of heterogeneous hierarchical integrated circuit chips. An initial port placement is provided on a layer for a macro. The initial port placement is expanded to provide a three-dimensional port shape including a plurality of metal layers along a z-axis. Wire routing of each of the macro level and a chip top level is defined within the expanded three-dimensional port shape. Each unnecessary metal layer of the expanded three-dimensional port shape is removed, providing a final three-dimensional port shape.

COOLER, STRUCTURE FOR TRANSPORTING AND METHOD OF TRANSPORTING THE SAME

A cooler, structure for transporting a cooler and a method for transporting the same are disclosed. The cooler has a cooling region defined by a support wall, a first wall, a second wall, and a sloped interior section, the sloped interior section extending between the first wall and the second wall and sloping away from the support wall. A discharge region is provided and is defined by the first wall, the second wall, the sloped interior section, and a vertical wall, the vertical wall being substantially parallel to the support wall. A frame member is positioned proximate the support wall. The frame member has support legs which extend therefrom in a direction way from the vertical wall. The frame member and support legs support the cooler when the cooler is rotated and positioned on a surface. 1. A cooler , comprising:a cooling region defined by a support wall, a first wall, a second wall, and a sloped interior section, the sloped interior section extending between the first wall and the second wall and sloping away from the support wall;a discharge region defined by the first wall, the second wall, the sloped interior section, and a vertical wall, the vertical wall being substantially parallel to the support wall; anda frame member positioned proximate the support wall, the frame member having support legs which extend therefrom in a direction way from the vertical wall,whereby, the frame member and support legs support the cooler when the cooler is rotated and positioned on a surface.2. The cooler of claim 1 , wherein the frame member has a horizontal member and at least two vertical members.3. The cooler of claim 2 , wherein the support legs are attached to the at least two vertical members.4. The cooler of claim 1 , wherein the frame member extends over portions of the support wall.5. The cooler of claim 4 , wherein portions of the frame member are adjustable to allow the frame member to be used with coolers of different sizes.6. The cooler of claim 4 , further ...

Systems And Methods For Authenticating Objects Using IR

Systems and methods authenticate an object using IR. IR is projected at a first wavelength onto the object and a first image of the object is captured during the projection of the IR. The object is authenticated by processing the first image to detect IR fluorescence from an IR fluorescing material incorporated into the object in response to the projected IR, where presence of the IR fluorescence within the first image indicates authentication of the object. 1. A system for authenticating an object configured with an infrared (IR) fluorescing material that fluoresces at a first IR wavelength when excited by IR of a second wavelength , comprising:an IR projector for projecting IR at a second wavelength onto the object;an IR camera having a field of view of the object for capturing an IR image of the object at the first wavelength; and controlling the IR projector to generate IR at the second wavelength and to project the IR at the second wavelength onto the object;', 'controlling the IR camera to capture the IR image; and', 'authenticating the objected based upon detected IR at the first wavelength within the IR image., 'a processor executing an algorithm to perform the steps of2. The system of claim 1 , further comprising an RGB camera for capturing an RGB image of the object claim 1 , wherein the RGB image and the IR image are processed to determine an identification of the object claim 1 , determine a location of the object claim 1 , and determine an orientation of the object.3. The system of claim 2 , further comprising a virtual environment stored within a memory claim 2 , wherein a virtual object is stored within the virtual environment based upon the determined identification claim 2 , location claim 2 , and orientation.4. The system of claim 3 , further comprising a display for displaying a rendered image of the virtual object within the virtual environment.5. A method for authenticating an object using IR claim 3 , comprising the steps of:projecting IR at a ...

CHANGING THE LOCATION OF A BUFFER BAY IN A NETLIST

In an embodiment, a buffer bay is represented with a moveable object that has a location within a unit in a netlist. The location of the moveable object that represents the buffer bay is changed to a new location in the netlist if changing the location improves placement within the unit. In an embodiment, a net weight of a net that connects the moveable object to an artificial pin is considered in determining whether to change the location to the new location. In an embodiment a bounding area that encompasses the location is considered in determining whether to change the location to the new location. 1. A computer-readable storage medium encoded with instructions , wherein the instructions when executed comprise:representing a buffer bay with a moveable object having a location within a unit in a netlist stored in a storage device;changing the location of the moveable object that represents the buffer bay to a new location in the netlist if changing the location improves placement within the unit, wherein the changing the location if the changing the location improves placement within the unit comprises considering a net weight in determining whether to change the location to the new location, wherein the considering the net weight in determining whether to change the location to the new location further comprises creating an artificial pin connected to the moveable object via a net;removing the artificial pin after the changing the location; andconverting the moveable object into a hole in the unit, wherein the hole is devoid of any circuit.2. The computer-readable storage medium of claim 1 , wherein the considering the net weight in determining whether to change the location to the new location further comprises:assigning the net weight to the net that connects the artificial pin to the moveable object.3. The computer-readable storage medium of claim 1 , wherein the net weight that is a higher priority than net weights of other nets increases a probability that ...

IMPLEMENTING Z DIRECTIONAL MACRO PORT ASSIGNMENT

A method, system and computer program product are provided for implementing an enhanced Z-directional macro port assignment or three-dimensional port creation for random logic macros of heterogeneous hierarchical integrated circuit chips. An initial port placement is provided on a layer for a macro. The initial port placement is expanded to provide a three-dimensional port shape including a plurality of metal layers along a z-axis. Wire routing of each of the macro level and a chip top level is defined within the expanded three-dimensional port shape. Each unnecessary metal layer of the expanded three-dimensional port shape is removed, providing a final three-dimensional port shape. 1. A computer-implemented method for implementing three-dimensional port creation for heterogeneous hierarchical integrated circuit chips comprising:using a computer, identifying an initial port placement for a macro;using a computer, extending a port shape of said initial port placement into a three-dimensional shape including a set number of metal layers; andusing a computer, defining wire routing for a chip top level and a macro level of the extended three-dimensional port shape.2. The computer-implemented method as recited in includes using a computer claim 1 , trimming said extended three-dimensional port shape to include selected metal layers responsive to defining wire routing for the chip top level and the macro level.3. The computer-implemented method as recited in includes enabling enhanced port wiring using said set number of metal layers to wire to a port based upon wiring density of each of said set number of metal layers.4. The computer-implemented method as recited in wherein using a computer claim 1 , defining wire routing for a chip top level and a macro level of the extended three-dimensional port shape includes using said number of metal layers and defining wire routing on a selected metal layer for said chip top level based upon wiring density of each of said set ...

SELF-TEST FOR ANALGESIC PRODUCT

Electrotransport drug delivery devices, system and methods of using configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices/systems may include an off-current module to determine that any current (e.g., which may be inferred by measuring potential difference between the anode and cathode of the device) flowing between the anode and cathode is below a threshold value when the device is not supposed to be delivering drug, thereby preventing unintended delivery of drug and/or alerting a user that unintended delivery of drug may occur. 1. An electrotransport drug delivery device that prevents unwanted delivery of drug while in an off state when , the device is powered on , the device comprising:an anode;a cathode;an activation circuit configured to apply current between the anode and cathode to deliver a drug by electrotransport when the device is in an on state and not in the off state; andan off-current module, the module configured to automatically and periodically determine if there is a current flowing between the anode and cathode when the activation circuit is in the off state while powered on.2. The device of claim 1 , wherein the off-current module comprises control logic.3. The device of claim 1 , wherein the off-current module comprises firmware claim 1 , software and/or hardware configured to determine if there is a potential difference between the anode and the cathode when the activation circuit is in the off state while powered on.4. The device of claim 1 , wherein the off-current module comprises software claim 1 , firmware and/or hardware configured to determine if there is a change in capacitance between the anode and cathode when the activation circuit is in the off state while powered on.5. The device of claim 1 , wherein the off-current module comprises software claim 1 , firmware and/or hardware configured to determine if there is a change in inductance ...

SYSTEM AND METHOD FOR DERIVING MATERIAL CHANGE ATTRIBUTES FROM CURATED AND ANALYZED DATA SIGNALS OVER TIME TO PREDICT FUTURE CHANGES IN CONVENTIONAL PREDICTORS

A system and method for deriving a material change attribute over time to predict a future change in at least one predictor, the method comprising: collecting precursor data from at least one data source; processing the precursor data by assessing at least one characteristic of the precursor data; generating at least one material change signal from the processed precursor data; evaluating the material change signal to determine the signal's value in predicting future changes in the predictor and, optionally, reverting to the collection and processing steps above to process additional precursor data; and generating at least one the material change attribute from the evaluated material change signal. 1. A computer implemented method for deriving a material change attribute over time to predict a future change in at least one predictor , said method comprising:collecting precursor data from at least one data source;processing said precursor data by assessing at least one characteristic of said precursor data;generating at least one material change signal from the processed precursor data;evaluating said material change signal to determine the signal's value in predicting future changes in said predictor; andgenerating at least one said material change attribute from the evaluated material change signal.2. The method according to claim 1 , wherein said data source is identified by use of sensing and/or learning process.3. The method according to claim 2 , wherein said learning process comprises heuristics focused on human behavior and/or human learning.4. The method according to claim 1 , wherein said processing of said precursor data comprises a curation process.5. The method according to claim 1 , wherein said characteristic is at least one selected from the group consisting of: trending claim 1 , measuring claim 1 , counting events claim 1 , counting sources claim 1 , noting order claim 1 , assessing continuity claim 1 , detecting interactions claim 1 , and combining ...

TWO-PART ELECTROTRANSPORT DEVICE

A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence. 1. (canceled)2. (canceled)3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)8. (canceled)9. (canceled)10. (canceled)11. (canceled)12. (canceled)13. (canceled)14. (canceled)15. (canceled)16. (canceled)17. (canceled)18. (canceled)19. (canceled)20. (canceled)21. (canceled)22. (canceled)23. (canceled)24. (canceled)25. (canceled)26. (canceled)27. (canceled)28. (canceled)29. (canceled)30. (canceled)31. A method of storing an electrotransport drug delivery device to resist corrosion prior to use , the method comprising:separately storing an electrical module and a reservoir module, so that circuitry in the electrical module is electrically isolated from a power source in the electrical module by a power-on contact between the circuitry and the power source when the electrical module is separated from the reservoir module, wherein the power source is isolated from the circuitry by the power-on contact while the power-on contact is open;combining the electrical module and the reservoir module to form a unitary, drug delivery device by connecting the circuitry via an electrical output to an input connector on the reservoir module,wherein combining the electrical module and the reservoir module causes ...

COUPLING GASKET AND BAR LINKAGE FOR FRICTION-FIT RANGE REDUCER

A seal for a pipe coupling can include an outer gasket defining a radially inner surface defining a plurality of grooves; and an inner gasket separably joined to the outer gasket and defining a radially outer surface, the radially outer surface defining a plurality of ridges extending radially outward and including: a first ridge, each of first and second side surfaces of the first ridge angled in cross-section with respect to a radial direction of the inner gasket towards a first axial end of the inner gasket when in an uncompressed state; and a second ridge, each of first and second side surfaces of the second ridge angled in cross-section with respect to the radial direction towards a second axial end of the inner gasket when in the uncompressed state; wherein the radially outer surfaces of the inner and outer gaskets contact each other. 1. A pipe coupling comprising:a coupling body defining a first body end and a second body end distal from the first body end, a coupling bore defined by and extending through the coupling body from the first body end to the second body end; a split ring defining a first ring end, a second ring end, and a radially inner surface; and', an outer gasket defining a radially outer surface and a radially inner surface, the radially inner surface of the outer gasket defining a plurality of grooves, each of a first side surface and a second side surface of a one of the plurality of grooves angled in cross-section with respect to a radial direction of the outer gasket towards a first axial end of the seal when the outer gasket is in an uncompressed state; and', 'an inner gasket separably joined to the outer gasket, the inner gasket defining a radially outer surface, the radially outer surface of the inner gasket defining a plurality of ridges engaged with the plurality of grooves of the outer gasket, each of a first side surface and a second side surface of a first ridge of the plurality of ridges angled in cross-section with respect to a ...

ONSITE MOBILE MANUFACTURING PLATFORM

A method of manufacturing a component of a water infrastructure system can include carrying a mobile manufacturing platform with a vehicle from a storage site to a worksite located remotely from the storage site, the mobile manufacturing platform including a control unit; and a manufacturing unit operatively coupled to the control unit; sending the solid model of a first component or an equivalent thereof to the manufacturing unit; fabricating a second component using an automated manufacturing process based on the solid model of the first component saved on a computer-readable storage medium operatively coupled to the control unit; and returning the system from the worksite to the storage site. 1. A mobile manufacturing system comprising:a control unit configured for ready portable transport via a vehicle from a storage site to a worksite and then back to the storage site, the worksite located remotely from the storage site;a three-dimensional scanner operatively coupled to the control unit and configured for portable transport via the vehicle to the worksite, the scanner configured to convert geometry of a first component of a water infrastructure system into electronic data based on a physical scan of the first component, a one of the scanner and the control unit comprising a converter configured to convert the data into a three-dimensional solid model of the first component; anda manufacturing unit operatively coupled to the control unit and configured for ready portable transport via the vehicle to the worksite, the manufacturing unit configured to fabricate a second component of the water infrastructure system using an automated manufacturing process based on the solid model of the first component.2. The system of claim 1 , wherein the control unit is configured to operatively couple to a server comprising a computer-readable storage medium claim 1 , the computer-readable storage medium configured to selectively store data sufficient for defining at least a ...

IMPLEMENTING ENHANCED NET ROUTING CONGESTION RESOLUTION OF NON-RECTANGULAR OR RECTANGULAR HIERARCHICAL MACROS

A method, system and computer program product are provided for implementing enhanced net routing for congestion resolution of non-rectangular or rectangular hierarchical macro designs of an integrated circuit chip. Congested macro nets near a macro boundary are identified. Wiring channels are reserved outside the macro boundary, allowing congested macro nets to be routed outside the physical boundary of the macro while still being logically contained within the macro. 1. A computer-implemented method for implementing enhanced net routing for congestion resolution of non-rectangular or rectangular hierarchical macro designs of an integrated circuit chip comprising:a computer system performing method steps of:identifying congested macro nets near a macro boundary; andreserving wiring channels outside the macro boundary, allowing congested macro nets to be routed outside the physical boundary of the macro while still being logically contained within the macro; said reserved wiring channels implementing the identified congested macro nets near said macro boundary.2. The computer-implemented method as recited in wherein identifying congested macro nets near a macro boundary includes analyzing child routing congestion for challenges.3. The computer-implemented method as recited in includes identifying child routing congestion with challenges near a child boundary.4. The computer-implemented method as recited in includes loading parent routing level and identifying parent routing congestion near the child boundary claim 3 , and identifying parent routing channels available.5. The computer-implemented method as recited in wherein reserving wiring channels outside the macro boundary includes creating a reserved parent area for child use.6. The computer-implemented method as recited in includes sizing and routing identified child routing congestion with challenges near the child boundary using routing wiring channels at the parent or top level of the hierarchical macro design ...

MACHINE LEARNING CLASSIFIER AND PREDICTION ENGINE FOR ARTIFICIAL INTELLIGENCE OPTIMIZED PROSPECT DETERMINATION ON WIN/LOSS CLASSIFICATION

Embodiments of a system and method for identifying and prioritizing company prospects by training at least one classifier on client company win/loss metrics. One or more classifiers can be trained on a training database compiled from company win/loss database for a client and firmographic data from a robust business entity database. Once trained, the system can employ Artificial Intelligence powered by the trained classifiers to classify and output customized prospect lists of thousands of profiled and scored companies that the AI has determined are likely targets for specific marketing and sales. The AI can also ingest databases of client targets and classify and score them based on the custom-trained classifier. 1. A system comprising:a transceiver for communicating over a network;a memory for storing at least instructions;a processor device that is operative to execute program instructions; a list of company engagements from a client user, and, for each engagement, a company identifier, wherein the list comprises won company engagements, and', 'company entity data mapped to each company engagement, the company entity data comprising firmographic data from a business entity information database,, 'a training database comprising'}a classification engine comprising at least one classifier configured to identify company prospects, the classification engine being configured to train the at least one classifier on the training data in the training database to identify one or more attractive classes and one or more unattractive classes to classify company prospects.2. The system of claim 1 , wherein the list of company engagements comprises a list of customers.3. The system of claim 2 , wherein the list of company engagements comprises claim 2 , for at least one of the engagements claim 2 , at least one of:a begin time for when the company became a customer;a customer revenue value;one or more employee identifiers.4. The system of claim 2 , wherein the list of won ...

CONSUMABLE STORAGE

An example system includes an imaging device and a consumable storage unit. The imaging device includes at least one consumable used in operation of the imaging device and a controller. The consumable storage unit includes at least one cavity to store a replacement consumable therein. The replacement consumable is inaccessible for use in operation of the imaging device. The controller is communicatively coupled to the consumable storage unit to receive a signal indicative of presence or absence of replacement consumable in the consumable storage unit. 1. A system , comprising: at least one consumable used in operation of the imaging device; and', 'a controller; and, 'an imaging device, comprisinga consumable storage unit including at least one cavity to store a replacement consumable therein, the replacement consumable being inaccessible for use in operation of the imaging device,wherein the controller is communicatively coupled to the consumable storage unit to receive a signal indicative of presence or absence of replacement consumable in the consumable storage unit.2. The system of claim 1 , wherein the consumable storage unit includes a door to control access to the at least one cavity.3. The system of claim 2 , wherein operation of the door is controlled by the controller.4. The system of claim 3 , wherein the imaging device includes a user interface to allow a user to access the door through the controller.5. The system of claim 3 , wherein controller is communicatively coupled to an electronic device and allows a user of the electronic device to access the door.6. The system of claim 1 , wherein the consumable storage unit is integrally formed with the imaging device.7. The system of claim 1 , wherein the consumable storage unit is a stand-alone unit separate from the imaging device.8. The system of claim 1 , wherein the consumable storage unit includes at least one indicator to indicate presence or absence of replacement consumable in the consumable storage ...

Valve body with integral bypass

A valve body with an integral bypass includes a primary valve body portion defining a primary internal surface, the primary internal surface defining a primary bore extending through the primary valve body portion from a primary upstream end to a primary downstream end; and the bypass seamlessly integrated with the primary valve body portion, the bypass defining a bypass internal surface, the bypass internal surface defining a bypass bore, the bypass bore comprising a bypass upstream bore and a bypass downstream bore, the bypass upstream bore extending through the primary upstream end of the primary valve body portion, the bypass downstream bore extending through the primary downstream end of the primary valve body portion, the bypass internal surface seamlessly intersecting the primary internal surface at the primary upstream end and the primary downstream end.

MONOLITHIC BYPASS

A method for forming a monolithic bypass includes pouring a molten metal into a monolithic bypass mold cavity of a mold, the monolithic bypass mold cavity shaped complimentary to a shape of the monolithic bypass; forming the monolithic bypass, the monolithic bypass comprising a bypass valve body disposed between an upstream conduit and a downstream conduit, an inlet opening defined by the upstream conduit, an outlet opening defined by the downstream conduit, a bypass bore extending through the upstream conduit, the bypass valve body, and the downstream conduit from the inlet opening to the outlet opening, the inlet opening and the outlet opening configured to attach to a primary valve body, the monolithic bypass defining a U-shape, the monolithic bypass and the bypass bore each being seamless; and removing the monolithic bypass from the mold. 1. A method for forming a monolithic bypass , the method comprising:pouring a molten metal into a monolithic bypass mold cavity of a mold, the monolithic bypass mold cavity shaped complimentary to a shape of the monolithic bypass;forming the monolithic bypass, the monolithic bypass comprising a bypass valve body disposed between an upstream conduit and a downstream conduit, an inlet opening defined by the upstream conduit, an outlet opening defined by the downstream conduit, a bypass bore extending through the upstream conduit, the bypass valve body, and the downstream conduit from the inlet opening to the outlet opening, the inlet opening and the outlet opening configured to attach to a primary valve body, the monolithic bypass defining a U-shape, the monolithic bypass and the bypass bore each being seamless; andremoving the monolithic bypass from the mold.2. The method of claim 1 , further comprising forming the mold through an additive manufacturing process.3. The method of claim 2 , wherein:the additive manufacturing process is a 3D sand printing process; and alternately depositing a substantially planar layer of sand; and ...

COMMUNICATION GENERATION IN COMPLEX COMPUTING NETWORKS

This disclosure is directed to communication generation by traversing routes of a graph in a complex computing network. The communication generation is used for determining whether an input signal has certain desired signal attributes. 1. A method for communication generation , based on traversing routes of a graph , in a complex computing network , the method comprising:establishing a first connection to a first input data system;receiving, from the first input data system, a first desired data attribute and a second desired data attribute;establishing a second connection to a second input data system;receiving, from the second input data system, first input data;establishing a third connection to a third input data system or the second input data system;accessing a graph stored at the third input data system or the second input data system, the graph comprising a plurality of data attributes and routes among at least some of the data attributes in the plurality of data attributes;sensing, using one or more computing device processors, a first data attribute associated with the first input data;determining, using the one or more computing device processors, the first data attribute is equivalent to the first desired data attribute;sensing, using the one or more computing device processors, a second data attribute associated with the first input data;determining, using the one or more computing device processors, the second data attribute is equivalent to the second desired data attribute;determining, using the one or more computing device processors, an intermediary data attribute on the graph, wherein a first route connects, either directly or indirectly, the intermediary data attribute to the first data attribute on the graph, and wherein a second route connects, either directly or indirectly, the intermediary data attribute to the second data attribute on the graph;determining, using the one or more computing device processors, a period of validity associated ...

ONSITE MOBILE MANUFACTURING PLATFORM

A mobile manufacturing platform including a control unit; a manufacturing unit operatively coupled to the control unit, the manufacturing unit configured to fabricate a component using an automated manufacturing process based on a three-dimensional solid model of the component; and a quality test unit operatively coupled to the control unit and configured to perform testing on one of the component and a sample of material used to fabricate the component; wherein the platform is configured for transport via a vehicle to a worksite. 1. A mobile manufacturing system comprising:a control unit configured for ready portable transport via a vehicle from a storage site to a worksite and then back to the storage site, the worksite located remotely from the storage site;a manufacturing unit operatively coupled to the control unit and configured for ready portable transport via the vehicle to the worksite, the manufacturing unit configured to fabricate a component of the water infrastructure system using an automated manufacturing process based on a three dimensional solid model of the component saved on a computer-readable storage medium operatively coupled to the control unit; anda quality test unit operatively coupled to the control unit and configured to perform testing on the component.2. The mobile manufacturing system of claim 1 , further comprising a transport device configured to transport at least one of raw materials claim 1 , partially fabricated parts claim 1 , and fabricated parts to the worksite.3. The mobile manufacturing system of claim 2 , wherein the transport device is an unmanned aerial vehicle (UAV).4. The mobile manufacturing system of claim 1 , further comprising a quality test unit operatively coupled to the control unit and configured to perform testing on the second component and on dog bone samples of a batch of a material used to fabricate the second component.5. The mobile manufacturing system of claim 1 , wherein the quality test unit is ...

VALVE BODY WITH IDENTIFICATION TAB

A valve body with an integral bypass includes a primary valve body portion defining a primary bore extending through the primary valve body portion from a primary upstream end to a primary downstream end, the primary bore defining an axis, the primary bore including a primary upstream bore extending through the primary upstream end and a primary downstream bore extending through the primary downstream end, the primary valve body portion configured to house a valve member between the primary upstream bore and the primary downstream bore; and the bypass seamlessly integrated with the primary valve body portion, the bypass defining a bypass bore, the bypass bore including a bypass upstream bore and a bypass downstream bore, the bypass including a bypass valve body disposed between the bypass upstream bore and the bypass downstream bore. 1. A valve body with an integral bypass comprising:a primary valve body portion defining a primary bore extending through the primary valve body portion from a primary upstream end to a primary downstream end, the primary bore defining an axis, the primary bore comprising a primary upstream bore extending through the primary upstream end and a primary downstream bore extending through the primary downstream end, the primary valve body portion configured to house a valve member between the primary upstream bore and the primary downstream bore; andthe bypass seamlessly integrated with the primary valve body portion, the bypass defining a bypass bore, the bypass bore comprising a bypass upstream bore and a bypass downstream bore, the bypass comprising a bypass valve body disposed between the bypass upstream bore and the bypass downstream bore, the bypass upstream bore extending through the primary upstream end and seamlessly intersecting the primary upstream bore, the bypass upstream bore extending radially outward and axially inward from the primary upstream bore to the bypass valve body relative to the axis, the bypass downstream bore ...

THREE-DIMENSIONALLY PRINTED CORE BOX BLANK

A method of manufacturing a cold box core includes injecting unbonded sand into a cold box core tool, the unbonded sand including sand mixed with a resin, the cold box core tool including: a first platen; a first insert half secured to the first platen; a second platen; and a second insert half secured to the second platen and configured to alternately mate with and separate from the first insert half, each of the first insert half and the second insert half being three-dimensionally printed from a polymer material, the first insert half and the second insert half together forming a cavity therebetween defining an outer geometric shape of the cold box core; and injecting gas into the unbonded sand to harden the cold box core. 1. A method of manufacturing a cold box core , the method comprising: a first platen;', 'a first insert half secured to the first platen;', 'a second platen; and', 'a second insert half secured to the second platen and configured to alternately mate with and separate from the first insert half, each of the first insert half and the second insert half being three-dimensionally printed from a polymer material, the first insert half and the second insert half together forming a cavity therebetween defining an outer geometric shape of the cold box core; and, 'injecting unbonded sand into a cold box core tool, the unbonded sand comprising sand mixed with a resin, the cold box core tool comprisinginjecting gas into the unbonded sand to harden the cold box core.2. The method of claim 1 , wherein each of the first insert half and the second insert half is formed from acrylonitrile butadiene styrene (ABS).3. The method of claim 2 , wherein each of the first insert half and the second insert half comprises a carbon fiber in-fill of between 20 percent and 30 percent claim 2 , inclusive claim 2 , by weight.4. The method of claim 1 , further comprising three-dimensionally printing each of the first insert half and the second insert half using a large scale ...

HEAT MANAGEMENT CONFIGURATIONS FOR CONTROLLING HEAT DISSIPATION FROM ELECTROSURGICAL INSTRUMENTS

In various embodiments, a surgical instrument is provided that may comprise an end effector for performing a surgical procedure on tissue, for example. The end effector may comprise at least one energy delivery surface and heat dissipation means for dissipating heat from at least a portion of the end effector. For example, in at least one embodiment, the end effector may comprise a first jaw, a second jaw, and a cutting member. The cutting member may comprise a cutting surface and a body, which may define a cavity and at least one opening communicating with the cavity. A fluid may be moved through the cavity to and/or from the opening(s). Additionally, in at least one embodiment, a surgical instrument's end effector may comprise a first jaw, a second jaw, a cutting member, and at least one heat pipe. Various other heat dissipation means are also disclosed. 1. A surgical instrument , comprising: a first jaw;', 'a second jaw, wherein the first jaw and the second jaw are operably coupled together; and', 'a cutting member configured to translate with respect to the first jaw, wherein the cutting member comprises a cutting surface and a body, wherein the body defines a cavity and at least one opening communicating with the cavity., 'an end effector comprising2. The surgical instrument of claim 1 , further comprising an elongate shaft and a handle operably coupled to the elongate shaft claim 1 , wherein the end effector is operably coupled to the elongate shaft claim 1 , and wherein the at least one cutting member opening is positioned between the handle and the cutting surface.3. The surgical instrument of claim 2 , wherein the cutting member is configured to translate between a retracted position and a fully advanced position with respect to the first jaw claim 2 , wherein the at least one cutting member opening is positioned between the first jaw and the handle when the cutting member is at the fully advanced position.4. The surgical instrument of claim 1 , wherein the ...

Current control for electrotransport drug delivery

Devices, systems and methods for controlling the application of current and/or voltage to deliver drug from patient contacts of an electrotransport drug delivery device by indirectly controlling and/or monitoring the applied current without directly measuring from the cathode of the patient terminal. In particular, described herein are electrotransport drug delivery systems including constant current delivery systems having a feedback current and/or voltage control module that is isolated from the patient contacts (e.g., anodes and cathodes). The feedback module may be isolated by a transistor from the patient contacts; feedback current and/or voltage control measurements may be performed at the transistor rather than at the patient contact (e.g., cathode).

Communication Generation in Complex Computing Networks

This disclosure is directed to communication generation by traversing routes of a graph in a complex computing network. The communication generation is used for determining whether certain input data has certain desired data attributes. 1. A method for communication generation , based on traversing routes of a graph , in a complex computing network , the method comprising:establishing a first connection to a first input data system;receiving, from the first input data system, a first desired data attribute and a second desired data attribute;establishing a second connection to a second input data system;receiving, from the second input data system, first input data;establishing a third connection to a third input data system or the second input data system;accessing a graph stored at the third input data system or the second input data system, the graph comprising a plurality of data attributes and routes among at least some data attributes in the plurality of data attributes;sensing, using one or more computing device processors, a first data attribute associated with the first input data;determining, using the one or more computing device processors, the first data attribute is equivalent to the first desired data attribute; transmitting, using the one or more computing device processors, a first communication to the first computing device, wherein the first communication is based on an intermediary attribute, wherein a first route connects, either directly or indirectly, the intermediary attribute to the first data attribute on the graph, and wherein a second route connects, either directly or indirectly, the intermediary data attribute to the second data attribute on the graph; and', 'receiving, using the one or more computing device processors, a first response, to the first communication, from the first computing device; and, 'executing, using the one or more computing device processors, a sensing operation to determine whether the first input data has a ...

OUTPUT ASSEMBLIES FOR PRINTERS

Example output assemblies for a printer device and printer devices incorporating the output assemblies are disclosed. In one example, the output assembly includes a support surface to support print media that is dispensed from the printer device along a feed direction. In addition, the output assembly includes a side surface that is coupled to the printer device and disposed above the support surface. The side surface is to transition between a first position and a second position. When the side surface is in the second position, the side surface is extended away from the printer device in the feed direction from the from the first position. 1. An output assembly for a printer device , the output assembly comprising:a support surface to support print media that is dispensed from the printer device along a feed direction; anda side surface that is coupled to the printer device and disposed above the support surface, wherein the side surface is to transition between a first position and a second position, wherein when the side surface is in the second position, the side surface is extended away from the printer device in the feed direction from the from the first position.2. The output assembly of claim 1 , wherein the side surface is disposed on a cam that is coupled to a shaft having a central axis claim 1 , and wherein the shaft is rotate about the central axis to transition the side surface between the first position and the second position.3. The output assembly of claim 2 , comprising a second cam coupled to the shaft claim 2 , wherein the second cam includes a second side surface claim 2 , and wherein the second cam is axially spaced from the cam along the central axis.4. The output assembly of claim 2 , comprising a driver coupled to the shaft claim 2 , wherein the driver is to rotate the shaft about the central axis.5. The output assembly of claim 4 , comprising:a first plurality of teeth coupled to the shaft; anda gear coupled to the driver that is engaged ...

ELECTROTRANSPORT DRUG DELIVERY DEVICES AND METHODS OF OPERATION

A switch-operated therapeutic agent delivery device. Embodiments of the operated therapeutic agent delivery device my include a switch that can be operated by a user, a device controller connected to the switch through a switch input where the device can actuate the device when certain predetermined conditions are met, following performance of both a digital switch validation test and an analog switch validation test. The switch operated therapeutic agent delivery device may have two parts, which are assembled by a user prior to use. These devices may be configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices may indirectly control and/or monitor the applied current without directly measuring from the cathode of the patient terminal. 1. A drug delivery device adapted to validate the operation of a user-selectable activation switch to deliver a dose of drug , the device comprising:a battery;a switch configured to be activated by a user to deliver a dose of drug; monitor the switch to determine a release event;', 'perform a digital validation of the switch following the release event using a dose switch circuit and failing the digital validation if a secondary digital input on a high side of the switch is low or if a secondary digital input on a low side of the switch is high;', 'perform an analog validation of the switch if the digital validation passes and failing the analog validation if a measurement of a high side voltage is less than a first predetermined fraction of a battery voltage for the drug delivery device or if a measurement of a low side voltage is greater than a second predetermined fraction of the battery voltage; and', 'initiate a failure mode for the drug delivery device if the analog validation of the switch fails., 'a controller configured validate operation of the switch, wherein the switch is user-activated to deliver a dose of a drug from a drug ...

ARCHITECTED MATERIALS AND STRUCTURES TO CONTROL SHOCK OUTPUT CHARACTERISTICS

A system that provides control of the output shockwave properties of energetic material wherein the system includes an energetic material having a first portion and a second portion. An additive manufacturing system combines the first portion and the second portion of the energetic material wherein the first portion and the second portion are positioned relative to each other to provide control of the output shockwave properties of the energetic material. 1. A method of producing an energetic device that includes control of output shockwave properties , comprising the steps of:providing an energetic material having at least a first portion and a second portion, andusing an additive manufacturing system for producing the energetic device by producing said energetic material by locating said first portion and said a second portion relative to each other to provide control of output shockwave properties of the device.2. The method of producing an energetic device of wherein said energetic material has a cylindrical shape.3. The method of producing an energetic device of wherein said energetic material has a cubical shape.4. The method of producing an energetic device of wherein said energetic material has an elongated cubical shape.5. The method of producing an energetic device ofwherein said energetic material is an explosive andwherein said first portion has a first detonation velocity andwherein second portion has a second detonation velocity andwherein said first detonation velocity is faster than said second detonation velocity, andwherein said first detonation velocity is related to said second detonation velocity in a manner to control of the output shockwave properties of said explosive.6. A method of producing a device that includes control the output shockwave properties of explosive material claim 1 , comprising the steps of:providing a first explosive material,providing a second explosive material, andusing an additive manufacturing system for producing the ...

FILL INDICATOR CAMS FOR PRINTER TRAYS

Example feed trays for a printer are disclosed. In one example, the feed tray includes a support surface to support print media, and a guide wall coupled to the support surface. The support surface and the guide wall define a feed path for the print media into the printer. In addition, the feed tray includes a fill indicator comprising a cam rotatably coupled to the guide wall about an axis of rotation that is perpendicular to the feed path. The cam includes an extension that extends radially from the axis of rotation, and the cam is rotatable about the axis of rotation between a first position and a second position. The extension is more proximate to the support surface when the cam is in the second position than when the cam is in the first position, and the cam is rotationally biased from the second position toward the first position. 1. A feed tray for a printer , the feed tray comprising:a support surface to support print media;a guide wall coupled to the support surface, wherein the support surface and the guide wall define a feed path for the print media into the printer; anda fill indicator comprising a cam rotatably coupled to the guide wall about an axis of rotation that is perpendicular to the feed path, wherein the cam includes an extension that extends radially from the axis of rotation;wherein the cam is rotatable about the axis of rotation between a first position and a second position, wherein the extension is more proximate to the support surface when the cam is in the second position than when the cam is in the first position, and wherein the cam is rotationally biased from the second position toward the first position.2. The feed tray of claim 1 , wherein the guide wall is movable along the support surface in a direction that is perpendicular to the feed path.3. The feed tray of claim 1 , wherein the extension of the cam comprises:a concave arcuate surface;a distal edge; anda planar surface;wherein the concave arcuate surface and the planar ...

Systems and Methods for Infrared Detection

A fluorescence detection system includes a light source for coupling with a mobile device and software, having machine readable instructions loadable into memory of the mobile device and executable by a processor of the mobile device, capable of: activating the light source in coordination with capturing one or more images using a camera of the mobile device; analyzing an image captured with the light source on with an image captured with the light source off, to detect a shift of intensity within a predetermined color range within the images; and identifying and authenticating objects by measuring the intensity shift within the images. 1. A fluorescence detection system , comprising:a light source for coupling with a mobile device; and activating the light source in coordination with capturing one or more images using a camera of the mobile device;', 'analyzing an image captured with the light source on with an image captured with the light source off, to detect a shift of intensity within a predetermined color range within the images; and', 'identifying and authenticating an object by measuring the intensity shift within the images., 'software, comprising machine readable instructions loadable into memory of the mobile device and executable by a processor of the mobile device, capable of2. The system of claim 1 , the light source comprising an LED adapted to plug into a port of the mobile device.3. The system of claim 2 , the LED sized to fit with the headphone jack of the mobile device.4. The system of claim 2 , the LED emitting at a wavelength of about 450 nm.5. The system of claim 4 , the step of analyzing comprising detecting a fluorescent response from an object tagged with an IR-fluorescing dye in the red wavelength band within the image in response to the emission from the LED.6. The system of claim 1 , the mobile device selected from the group of a mobile phone claim 1 , a tablet claim 1 , a laptop computer claim 1 , a notebook computer claim 1 , an MP3 ...

Coupling gasket with friction-fit range reducer

A seal for a pipe coupling includes an outer gasket defining a radially inner surface defining a plurality of grooves; and an inner gasket separably joined to the outer gasket, a radially outer surface of the inner gasket defining a plurality of ridges, each of the plurality of ridges extending radially outward, the plurality of ridges including: a first ridge, each of first and second side surfaces of the first ridge angled in cross-section with respect to a radial direction of the inner gasket towards a first axial end of the inner gasket; and a second ridge, each of a first and second side surfaces of the second ridge angled in cross-section with respect to a radial direction of the inner gasket towards a second axial end of the inner gasket; wherein the radially outer surface of the inner gasket contacts the radially inner surface of the outer gasket.

ELECTROTRANSPORT DRUG DELIVERY DEVICE

A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence. 1. An electrotransport drug delivery system comprising an electrical module and a reservoir module that are combined to form a unitary , activated drug delivery system prior to use , wherein:the electrical module comprises:control circuitry;an electrical output connected to the control circuitry;two or more power-on contacts between the control circuitry and a battery; andthe battery, which is isolated from the control circuitry by the two or more power-on contacts while at least one of the two or more power-on contacts remains open, and which is connected into the control circuitry when all of the two or more power-on contacts are closed by a battery contact actuator on the reservoir module when the electrical module and the reservoir module are combined; and a pair of electrodes;', 'an electrical input that is separate from the electrical output until the electrical module and reservoir module are combined, wherein the electrical input connects the control circuitry to the pair of electrodes when the electrical module is combined with the reservoir module; and', 'two or more battery contact actuators each configured to close a corresponding power-on contacts of the two or more power-on contacts when the ...

ARTIFICIALLY INTELLIGENT COMMUNICATION GENERATION IN COMPLEX COMPUTING NETWORKS

This disclosure is directed to artificially intelligent (AI) communication generation by traversing routes of a graph in a complex computing network. The intelligent communication generation is used for determining whether an input signal has certain desired signal attributes. 1. An apparatus for artificially intelligent (AI) communication generation by traversing routes of a graph in a complex computing network , the intelligent communication generation being used for determining whether an input signal has desired signal attributes , the intelligent communication generation and the traversing of the graph being rooted in computing technology , the apparatus comprising: establishing a first connection to a first input signal system;', 'receiving, from the first input signal system, a first desired signal attribute and a second desired signal attribute;', 'establishing a second connection to a second input signal system;', 'receiving, from the second input signal system, a first input signal;', 'establishing a third connection to a third input signal system;', 'accessing a graph stored at the third input signal system, the graph comprising a plurality of signal attributes and routes between at least some of the signal attributes in the plurality of signal attributes;', 'transmitting communications to a first computing device associated with the first input signal; and', 'receiving responses to the communications from the first computing device associated with the first input signal;, 'a signal communication interface for 'sensing a first signal attribute associated with the first input signal;', 'a signal sensor fora memory for storing instructions for execution by the signal processor; and determining the first signal attribute is equivalent to the first desired signal attribute;', 'determining, for the first input signal, a second signal attribute not sensed by the signal sensor, the second signal attribute being equivalent to the second desired signal attribute ...

MONOLITHIC BYPASS

A monolithic bypass includes an upstream conduit, the upstream conduit defining a first end and a second end, the upstream conduit defining an upstream bore extending from the first end to the second end, the first end defining an inlet opening to the upstream bore; a downstream conduit, the downstream conduit defining a first end and a second end, the downstream conduit defining a downstream bore extending from the first end to the second end, the first end defining an outlet opening to the downstream bore; and a bypass valve body seamlessly connected to the second end of the upstream conduit and the second end of the downstream conduit, the bypass valve body defining a bypass body bore, the upstream bore, the downstream bore, and the bypass body bore defining a seamless bypass bore extending from the inlet opening to the outlet opening; wherein the monolithic bypass is substantially U-shaped. 1. A monolithic bypass comprising:an upstream conduit, the upstream conduit defining a first end and a second end, the upstream conduit defining an upstream bore extending from the first end to the second end, the first end defining an inlet opening to the upstream bore;a downstream conduit, the downstream conduit defining a first end and a second end, the downstream conduit defining a downstream bore extending from the first end to the second end, the first end defining an outlet opening to the downstream bore; anda bypass valve body seamlessly connected to the second end of the upstream conduit and the second end of the downstream conduit, the bypass valve body defining a bypass body bore extending from the second end of the upstream conduit to the second end of the downstream conduit, the bypass body bore intersecting the upstream bore and the downstream bore, the bypass body bore defining a bypass body bore axis, the upstream bore, the downstream bore, and the bypass body bore defining a seamless bypass bore extending from the inlet opening to the outlet opening; ...

SELF-TEST FOR ANALGESIC PRODUCT

Electrotransport drug delivery devices, system and methods of using configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices/systems may include an off-current module to determine that any current (e.g., which may be inferred by measuring potential difference between the anode and cathode of the device) flowing between the anode and cathode is below a threshold value when the device is not supposed to be delivering drug, thereby preventing unintended delivery of drug and/or alerting a user that unintended delivery of drug may occur. 1. An electrotransport drug delivery device that prevents unwanted delivery of drug while in an off state when the device is powered on , the device comprising:an anode and a cathode;an activation circuit configured to apply current between the anode and cathode to deliver a drug by electrotransport when the device is in an on state and not in the off state; andwherein the device is configured to shut down when there is a current flowing between the anode and cathode that is greater than an Output Current Off threshold when the device is in an off state while powered on;further wherein the device is configured to automatically and periodically determine if there is a current flowing between the anode and cathode when the activation circuit is in the off state while powered on.2. The device of claim 1 , wherein the device is configured to determine if there is a potential difference between the anode and the cathode when the activation circuit is in the off state while powered on.3. The device of claim 1 , further configured to determine if there is a change in capacitance between the anode and cathode when the activation circuit is in the off state while powered on.4. The device of claim 1 , further configured to determine if there is a change in inductance between the anode and cathode when the activation circuit is in the off state while powered ...

VALVE BODY WITH IDENTIFICATION TAB

A valve body includes a flange; and an identification tab disposed on the flange, the identification tab defining indicia. A pipe system includes a first flange; a second flange fastened to the first flange by a plurality of fasteners; and an identification tab disposed on the first flange, the identification tab defining indicia. 1. A valve body comprising:a flange; andan identification tab disposed on the flange, the identification tab defining indicia.2. The valve body of claim 1 , wherein:the flange defines an outer circumferential surface; andthe identification tab is disposed on the outer circumferential surface.3. The valve body of claim 2 , wherein the identification tab extends outward beyond a radius of the outer circumferential surface.4. The valve body of claim 1 , wherein the indicia indicate a design standard for the flange.5. The valve body of claim 1 , wherein:the identification tab defines an indicia surface;the indicia are defined by the indicia surface of the identification tab;the flange defines a flange face; andthe indicia surface is angled away from the flange face.6. The valve body of claim 5 , wherein:the flange defines an outer circumferential surface; andthe indicia surface extends outwards from the outer circumferential surface.7. The valve body of claim 1 , wherein the identification tab comprises a label claim 1 , and wherein the label defines the indicia.8. The valve body of claim 1 , wherein the indicia are recessed into an indicia surface of the identification tab.9. The valve body of claim 1 , wherein the indicia are raised from an indicia surface of the identification tab.10. A pipe system comprising:a first flange;a second flange fastened to the first flange by a plurality of fasteners; andan identification tab disposed on the first flange, the identification tab defining indicia.11. The pipe system of claim 10 , wherein the indicia are visible when the first flange is fastened to the second flange.12. The pipe system of claim 11 ...

Alpha-v beta-6 integrin-binding antibody fragments

The present invention provides isolated, engineered multivalent antibody fragments that specifically bind α V β 6 integrin. In particular embodiments, the antibody fragments of the present invention further comprise an imaging agent and/or a therapeutic agent. In some instances, the antibody fragments also include unnatural amino acids and/or inserted cysteine or thiol residues at the C-terminus of the scFv molecules of the fragments. The anti-α V β 6 integrin antibody fragments provided herein are particularly useful for imaging a tumor, organ or tissue and for treating an α V β 6 integrin-mediated disease or disorder. Compositions and kits containing the multivalent antibody fragments of the present invention are also described herein.

METHOD OF MANUFACTURING A COLD BOX CORE

A method of manufacturing a cold box core includes injecting unbonded sand into a cold box core tool, the unbonded sand including sand mixed with a resin, the cold box core tool including: a first platen; a first insert half secured to the first platen; a second platen; and a second insert half secured to the second platen and configured to alternately mate with and separate from the first insert half, each of the first insert half and the second insert half being three-dimensionally printed from a polymer material, the first insert half and the second insert half together forming a cavity therebetween defining an outer geometric shape of the cold box core; and injecting gas into the unbonded sand to harden the cold box core. 1. A method of manufacturing a cold box core , the method comprising: a first platen;', 'a first insert half secured to the first platen;', 'a second platen; and', 'a second insert half secured to the second platen and configured to alternately mate with and separate from the first insert half, each of the first insert half and the second insert half being three-dimensionally printed from a polymer material, the first insert half and the second insert half together forming a cavity therebetween defining an outer geometric shape of the cold box core; and, 'injecting unbonded sand into a cold box core tool, the unbonded sand comprising sand mixed with a resin, the cold box core tool comprisinginjecting gas into the unbonded sand to harden the cold box core.2. The method of claim 1 , wherein each of the first insert half and the second insert half is formed from acrylonitrile butadiene styrene (ABS).3. The method of claim 2 , wherein each of the first insert half and the second insert half comprises a carbon fiber in-fill of between 20 percent and 30 percent claim 2 , inclusive claim 2 , by weight.4. The method of claim 1 , further comprising three-dimensionally printing each of the first insert half and the second insert half using a large scale ...

Heat management configurations for controlling heat dissipation from electrosurgical instruments

In various embodiments, a surgical instrument is provided that may comprise an end effector for performing a surgical procedure on tissue, for example. The end effector may comprise at least one energy delivery surface and heat dissipation means for dissipating heat from at least a portion of the end effector. For example, in at least one embodiment, the end effector may comprise a first jaw, a second jaw, and a cutting member. The cutting member may comprise a cutting surface and a body, which may define a cavity and at least one opening communicating with the cavity. A fluid may be moved through the cavity to and/or from the opening(s). Additionally, in at least one embodiment, a surgical instrument's end effector may comprise a first jaw, a second jaw, a cutting member, and at least one heat pipe. Various other heat dissipation means are also disclosed.

Electrosurgical cutting and sealing instrument

A surgical instrument for supplying energy to tissue can comprise a jaw member comprising an electrode, wherein the electrode is configured to supply energy from a power source to captured tissue. The surgical instrument comprises a tissue-cutting element to transect the captured tissue. The rate of distal translation of the tissue-cutting element during the operational stroke may be regulated by an electromagnetic brake.

Surgical instruments with electrodes

A surgical stapling assembly is configured to be used to form a tissue seal having an arcuate portion. The surgical stapling assembly comprises an end-effector extending from the distal end of the shaft. The end-effector comprises a first portion and a second portion. The first portion comprises a first face at least partially surrounding the aperture, a staple cavity defined in the first face, a staple removably positioned within the staple cavity, and a first electrode positioned one of on and proximate to the first face. The second portion comprises a second face, an anvil pocket defined in the second face, and a second electrode positioned one of on and proximate to the second face, and a second electrode. The first electrode and the second electrode each comprise an arcuate portion. The first electrode has a different polarity than the second electrode.

Electrosurgical instrument comprising sequentially activated electrodes

An electrosurgical surgical instrument can comprise a handle and an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed to capture tissue therebetween. One or both of the first and second jaws can comprise a plurality of electrodes which can be sequentially activated. The electrodes can be activated in a predetermined order in connection with a cutting member being advanced through the tissue. In various embodiments, the electrodes can be deactivated in a predetermined order. In certain embodiments, the electrodes can be comprised of a positive temperature coefficient material which can allow the electrodes to be sequentially deactivated.

Heat management configurations for controlling heat dissipation from electrosurgical instruments

In various embodiments, a surgical instrument is provided that may comprise an end effector for performing a surgical procedure on tissue, for example. The end effector may comprise at least one energy delivery surface and heat dissipation means for dissipating heat from at least a portion of the end effector. For example, in at least one embodiment, the end effector may comprise a first jaw, a second jaw, and a cutting member. The cutting member may comprise a cutting surface and a body, which may define a cavity and at least one opening communicating with the cavity. A fluid may be moved through the cavity to and/or from the opening(s). Additionally, in at least one embodiment, a surgical instrument's end effector may comprise a first jaw, a second jaw, a cutting member, and at least one heat pipe. Various other heat dissipation means are also disclosed.

BIOSENSOR METER WITH INSERTABLE MEMORY MODULE.

SE PRESENTA UN MEDIDOR DE BIODETECCION (10) QUE ESTA CAPACITADO PARA RECIBIR UNA BANDA DE MUESTRA (18) QUE INCLUYE UN RECEPTACULO DE MUESTRA (20) CON UN REACTIVO DE ANALISIS EN EL MISMO Y ELECTRODOS (24, 26) EN CONTACTO CON EL MISMO. EL MEDIDOR DE BIODETECCION (10) INCLUYE UNA FUENTE DE ALIMENTACION DE EXCITACION (44) PARA SUMINISTRAR POTENCIALES AL ELECTRODO DE LA BANDA DE MUESTRA (24). TAMBIEN SE SUMINISTRA UN AMPLIFICADOR DE SALIDA (50) PARA SU CONEXION A OTRO ELECTRODO (26) DE UNA BANDA DE MUESTRA INSERTADA (18) Y PRODUCE UNA SEÑAL DE SALIDA INDICATIVA DE LAS CORRIENTES DETECTADAS CUANDO EL FLUIDO QUE CONTIENE LA SUSTANCIA ANALIZADA ESTA PRESENTE EN EL RECEPTACULO DE MUESTRAS DE LA BANDA. UNA TECLA DE MEMORIA INSERTABLE (30) PUEDE INSERTARSE EN EL INTERIOR DEL MEDIDOR (10) E INCLUYE UNA PLURALIDAD DE VALORES DE PARAMETROS Y RUTINAS DE PROCEDIMIENTOS ALMACENADOS QUE CONTROLAN LAS OPERACIONES DEL MEDIDOR. UN MICROPROCESADOR (59) ES SENSIBLE A UNA RUTINA DE PROCEDIMIENTO Y A LOS VALORES DEPARAMETRO ACCEDIDOS A PARTIR DE LA TECLA DE MEMORIA INSERTABLE (30) PARA PROVOCAR QUE EL SUMINISTRO DE EXCITACION SE APLIQUE A UNA PLURALIDAD DE POTENCIALES EN DURACIONES PREDETERMINADAS, TANTO LOS VALORES DE LOS POTENCIALES COMO LA DURACION DE TIEMPO DE SU APLICACION SE DETERMINAN A PARTIR DE LOS VALORES DE LOS PARAMETROS DERIVADOS DE LA TECLA DE MEMORIA.

Biosensing meter with fail/safe procedures to prevent erroneous indications

A biosensing meter receives a sample strip that includes electrically isolated sense and excitation electrodes bridged by a reaction zone. When a drop of biological sample fluid is placed in the reaction zone, a plurality of fail/safe tests are performed. A drop size test is performed by a circuit that detects the size of the drop placed in the reaction zone. The circuit both detects that a drop has been placed in the reaction zone and further measures a test current level, after a delay, to determine that the drop size is sufficient to enable hydration of reactants in the reaction zone. Subsequently, during the reaction, a "delta" current change is measured at succeeding sample time. This test measures the difference between succeeding current samples during a measurement time. If each succeeding sample is not less than preceding sample by a delta value, a determination is made that the current is not monotonically decreasing and the test is aborted. At the termination of the measurement time, a current sum test is performed wherein a processor calculates a linear sum of all sample test currents and calculates a ratio between that sum and the last current sample. If that ratio matches a pre-calculated constant for the Cottrell relationship, then it is known that the measurement values exhibit the Cottrell relationship.

Biosensor electrode excitation circuit

A circuit is described for applying a potential to an electrode of a biosensing test cell, which electrode, when properly inserted in a female connector, is contacted by a pair spaced apart contacts. The circuit includes a source of excitation potential and an operational amplifier having one input connected to the source of excitation potential. A switching circuit is coupled between the operational amplifier and a first one of the spaced apart contacts, with the switch means exhibiting an impedance. A feedback circuit is connected between the second of the spaced-apart contacts and another input to the operational amplifier, to feed back a potential appearing at the second contact. The feedback is for the purpose of maintaining the output of the operational amplifier at a level which compensates for impedance losses in the swtiching circuit. The feedback circuit enables the output of the operational amplifier to be varied so that the potential applied to the electrode is equal to the source of excitation potential. A further circuit is connected to the feedback circuit for sensing when an open or high impedance state exists between the spaced-apart contacts.

Biosensing instrument and method

A biosensing system is described which determines whether a measured current is varying in accordance with a predetermined Cottrell current relationship. The system includes a test cell with at least a pair of electrodes which extend into a reaction zone, which reaction zone includes analyte reactants. An analog signal detector, in combination with a microprocessor, take plurality of current measurements between the electrodes over a plurality of succeeding measurement times, after a sample is placed in contact with the analyte reactants in the reaction zone. The microprocessor also stores a plurality of succeeding cpmparison constants which are derived by taking the inverse ratio of the square root of a measurement time divided by the square root of a subsequent measurement time. The microprocessor selects a pair of succeeding measurement times; derives a ratio of the currents measured at those times; and then compares the ratio of those currents with the comparison constant previously derived for the pair of succeeding measurement times. If the comparison indicates that the measured current ratio is dissimilar from the comparison constant, an indication is developed that the current between the electrodes is not varying in accordance with the Cottrell relationship. The plurality of current measurements are also used to calculate total charge transferred, Q. Q can then be used as a second means of calculating the final result.

Methods for imaging the anatomy with an anatomically secured scanner assembly

A method for viewing a portion of a patient's anatomy that comprises placing a scanner assembly including an oscillating reflector in the anatomy, securing the scanner assembly to an anatomical structure, scanning the anatomy with the scanner assembly secured to the anatomical structure, collecting radiation returned from the scanned anatomy, and generating a displayable image of the anatomy.

Two-part electrotransport device

Disclosed is a corrosion-resistant electrotransport drug delivery device. The device comprises an electrical module (20) and a reservoir module (30). The electrical module (20) and the reservoir module (30) are configured to be combined to form a unitary and activated drug delivery device prior to use. The device resists corrosion by electrically isolating a circuitry in the electrical module (20) from a power source. The electrical module comprises the circuitry (248), an electrical output and at least two power-on contacts (218) between the circuitry and a battery (290). The electrical output is adapted to connect the circuitry to an input connector on the reservoir module (30) when the electrical module (20) is combined with the reservoir module (30). The battery (290) is isolated from the circuitry (248) by the power-on contacts (218) while at least one of the power-on contacts (218) remain open and the battery (290) is connected into the circuitry (248) when all of the power-on contacts (218) are closed by battery contact actuators on the reservoir module (30) when the electrical module (20) and the reservoir module (30) are combined. The reservoir module (30) comprises an electrical input and at least two battery contact actuators (318). The electrical input adapted to electrically connect the circuitry (248) in the electrical module (20) to at least a pair of active electrodes in the reservoir module (30) when the electrical module (20) is combined with the reservoir module (30). The at least two battery contact actuators (318) are configured to close a corresponding power-on contact (218) when the electrical module (20) is combined with the reservoir module (30) so that the battery (290) is connected into the circuitry (248) and the device is powered on. The at least two battery contact actuators (318) are separated from each other. se. The device resists corrosion by electrically isolating a circuitry in the electrical module (20) from a power source. The ...

Biosensing meter with pluggable memory key

A biosensing meter (10) is en-abled to receive a sample strip (18) that includes a sample well (20) with an analyte reactant therein and electrodes (24, 26) in contact there-with. The biosensing meter (10) includes an excitation supply (44) for supplying potentials to a sam-ple strip electrode (24). A sense amplifier (50) is also provided for connection to another electrode (26) of an inserted sample strip (18) and produces an output signal indica-tive of sensed currents when an an-alyte containing fluid is present in the strip's sample well. A pluggable memory key (30) is insertable into the meter (10) and includes a plural-ity of stored parameter values and procedure routines that control op-erations of the meter. A micropro-cessor (59) is responsive to a pro-cedure routine and parameter values accessed from the pluggable mem-ory key (30) to cause the excitation supply to apply a plurality of poten-tials for preset durations, both the values of the potentials and the time duration of their application are de-termined from parameter values de-rived from the memory key.

Two-part electrotransport device

A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.

Fill indicator rollers for printer trays

Example feed trays for a printer are disclosed. In one example, the feed tray includes a support surface to support print media, and a guide wall coupled to the support surface. The support surface and the guide wall define a feed path for the print media into the printer, and the guide wall is movable along the support surface. In addition, the feed tray includes a fill indicator comprising a roller mounted to the guide wall that extends into the feed path. The roller is to rotate about an axis of rotation that is perpendicular to the feed path.

Biosensing meter with fail/safe procedures to prevent erroneous indications

A biosensing meter (22) receives a sample strip (10) that includes electrically isolated sense and excitation electrodes (12,14) bridged by a reaction zone. When a drop of biological sample fluid is placed in the reaction zone, a plurality of fail/safe tests are performed. A drop size test is performed by a circuit that detects the size of the drop placed in the reaction zone. The circuit both detects that a drop has been placed in the reaction zone and further measures a test current level, after a delay, to determine that the drop size is sufficient to enable hydration of reactants in the reaction zone.

Regulated bifurcated power supply

The regulated power supply employs two separate sources of power (28, 30) which are serially connected by a variable impedance element, such as a transistor (32), connected between the two power sources. Output vol-tage of the power supply is equal to the sum of the individual power supply voltages minus a voltage drop across the variable impedance element. A sensor circuit (38) employing standby and active mode branches (40, 42) is coupled between output terminals of the pow-er supply for control of the variable imped-ance element. The active branch of the sensor is switchably connected to an output power terminal (22) of the supply so as to be opera-tive only during the active mode. The standby branch comprises a resistive network (52) cou-pled to a reference diode (44) while the active branch comprises a feedback amplifier (58) coupled to the reference diode.

Systems and methods for infrared detection

Door latch

A cabinet includes a frame portion and a door hingedly connected to the frame portion. A member is rigidly connected to the door and includes a flange portion extending from and spaced apart from an outer surface of the door. A handle is pivotably connected to the door and includes a user graspable portion disposed between the first outer surface of the door and the flange portion of the member. A catch member is rigidly connected to the user graspable portion and extends through a slot in the door for interlocking engagement with a retention feature disposed on the frame portion. When the door is in a closed position, handle is pivotable with respect to the door from a door retention position to a door release position for disengagement of the catch member from the door retention feature.

Biosensing meter with fail/safe procedures to prevent erroneous indications

Biosensing meter for receiving a sample strip that includes a pair of electrodes, an analyte reactant containing reaction zone bridging the pair of electrodes, and processor means coupled to the sense amplifier means. During operation of the biosensing meter the processor means tests if the output signal (64) exceeds a first threshold value (68), an output signal that exceeds the first threshold value (68) being recognized as an indication of application of the biological sample to the reaction zone (20). In a second test the processor tests if the output signal (64) thereafter exceeds a second larger threshold value (72), an output signal that exceeds the second larger threshold value (72) being recognized as an indication that the volume is adequate for enabling a subsequent determination to be made for an analyte in the biological fluid, the processor means only enabling the subsequent determination after the second, larger threshold (72) has been exceeded by the output signal (64).

System and method for deriving material change attributes from curated and analyzed data signals over time to predict future changes in conventional predictors

A system and method for deriving a material change attribute over time to predict a future change in at least one predictor, the method comprising: collecting precursor data from at least one data source; processing the precursor data by assessing at least one characteristic of the precursor data; generating at least one material change signal from the processed precursor data; evaluating the material change signal to determine the signal's value in predicting future changes in the predictor and, optionally, reverting to the collection and processing steps above to process additional precursor data; and generating at least one the material change attribute from the evaluated material change signal.

System and method for deriving material change attributes from curated and analyzed data signals over time to predict future changes in conventional predictors

Sample pooling assay

Provided herein are compositions and methods for detecting nucleic acids in pooled samples.

Current control for electrotransport drug delivery

Electrosurgical instrument comprising sequentially activated electrodes

An electrosurgical surgical instrument can comprise a handle and an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed to capture tissue therebetween. One or both of the first and second jaws can comprise a plurality of electrodes which can be sequentially activated. The electrodes can be activated in a predetermined order in connection with a cutting member being advanced through the tissue. In various embodiments, the electrodes can be deactivated in a predetermined order. In certain embodiments, the electrodes can be comprised of a positive temperature coefficient material which can allow the electrodes to be sequentially deactivated.

BIOS SENSOR WITH FAILSAFE OPERATING PROCEDURE TO AVOID FALSE DISPLAYS

Current control for electrotransport drug delivery.

Dispositivos, sistemas y métodos para controlar la aplicación de corriente y/o voltaje para administrar fármaco desde contactos de paciente de un dispositivo de administración de fármacos por electrotransporte al controlar y/o monitorizar de manera indirecta la corriente aplicada sin medir directamente desde el cátodo de la terminal del paciente. En particular, se describen en la presente sistemas de administración de fármacos por electrotransporte que incluyen sistemas de distribución de corriente constante que tienen un módulo de control de voltaje y corriente de retroalimentación que está aislado de los contactos de paciente (por ejemplo, ánodos y cátodos). EL módulo de retroalimentación se puede aislar por un transistor de los contactos de paciente; se pueden realizar medición de control de voltaje y/o corriente de retroalimentación en el transistor en lugar de en el contacto de paciente (por ejemplo, cátodo).

Biosensing meter with fail/safe procedures to prevent erroneous indications

A biosensing meter (22) receives a sample strip (10) that includes electrically isolated sense and excitation electrodes (12, 14) bridged by a reaction zone. When a drop of biological sample fluid is placed in the reaction zone, a plurality of fail/safe tests are performed. A drop size test is performed by a circuit that detects the size of the drop placed in the reaction zone. The circuit both detects that a drop has been placed in the reaction zone and further measures a test current level, after a delay, to determine that the drop size is sufficient to enable hydration of reactants in the reaction zone.

Monolithic bypass

A monolithic bypass includes an upstream conduit, the upstream conduit defining a first end and a second end, the upstream conduit defining an upstream bore extending from the first end to the second end, the first end defining an inlet opening to the upstream bore; a downstream conduit, the downstream conduit defining a first end and a second end, the downstream conduit defining a downstream bore extending from the first end to the second end, the first end defining an outlet opening to the downstream bore; and a bypass valve body seamlessly connected to the second end of the upstream conduit and the second end of the downstream conduit, the bypass valve body defining a bypass body bore, the upstream bore, the downstream bore, and the bypass body bore defining a seamless bypass bore extending from the inlet opening to the outlet opening; wherein the monolithic bypass is substantially U-shaped.

Valve body with integral bypass

A valve body with an integral bypass includes a primary valve body portion defining a primary internal surface, the primary internal surface defining a primary bore extending through the primary valve body portion from a primary upstream end to a primary downstream end; and the bypass seamlessly integrated with the primary valve body portion, the bypass defining a bypass internal surface, the bypass internal surface defining a bypass bore, the bypass bore comprising a bypass upstream bore and a bypass downstream bore, the bypass upstream bore extending through the primary upstream end of the primary valve body portion, the bypass downstream bore extending through the primary downstream end of the primary valve body portion, the bypass internal surface seamlessly intersecting the primary internal surface at the primary upstream end and the primary downstream end.

Current control for electrotransport drug delivery

Devices, systems and methods for controlling the application of current and/or voltage to deliver drug from patient contacts of an electrotransport drug delivery device by indirectly controlling and/or monitoring the applied current without directly measuring from the cathode of the patient terminal. In particular, described herein are electrotransport drug delivery systems including constant current delivery systems having a feedback current and/or voltage control module that is isolated from the patient contacts (e.g., anodes and cathodes). The feedback module may be isolated by a transistor from the patient contacts; feedback current and/or voltage control measurements may be performed at the transistor rather than at the patient contact (e.g., cathode).

Electrotransport device IN TWO PARTS

Biosensing meter with ambient temperature estimation method and system

Machine learning classifier and prediction engine for artificial intelligence optimized prospect determination on win/loss classification

Biosensing meter with pluggable memory key

Two-part electrotransport device.

Se describe un dispositivo de suministro de agente terapéutico operado por conmutador. El dispositivo comprende dos partes, las cuales son ensambladas por un usuario antes del uso. Una primera parte contiene un suministro de energía y circuitería para el dispositivo; y una segunda parte comprende electrodos y depósitos que contienen el agente terapéutico que es suministrado. La acción de la combinación de las dos partes del dispositivo causa que las dos partes sean acopladas conjuntamente de manera irreversible, completa una conexión eléctrica entre las dos partes y cierra uno o más conmutadores, conectando de ese modo una fuente de energía, tal como una batería, en la circuitería del dispositivo, alimentando de ese modo el dispositivo de modo que está listo para el uso. El dispositivo luego se puede unir a un paciente, quien puede operar el dispositivo al presionar un botón en una secuencia apropiada.

Regulated bifurcated power supply

A regulated power supply employs two separate sources of power which are serially connected by a variable impedance element, such as a transistor, connected between the two power sources. Output voltage of the power supply is equal to the sum of the individual power supply voltages minus a voltage drop across the variable impedance element. A sensor circuit employing standby and active mode branches is coupled between output terminals of the power supply for control of the variable impedance element. The active branch of the sensor is switchably connected to an output power terminal of the supply so as to be operative only during the active mode. The standby branch comprises a resistive network coupled to a reference diode while the active branch comprises a feedback amplifier coupled to the reference diode.

Self-test for analgesic product

electrotransport drug release current control

resumo patente de invenção: "controle de corrente para liberação de droga de eletrotransporte". dispositivos, sistemas e métodos para controlar a aplicação de corrente e/ou voltagem para liberar droga de contatos de paciente de um dispositivo de liberação de droga de eletrotransporte controlando e/ou monitorando indiretamente a corrente aplicada sem medir diretamente a partir do catodo do terminal de paciente. em particular, são descritos no presente documento sistemas de liberação de droga de eletrotransporte incluindo sistemas de liberação de corrente constante tendo uma corrente de realimentação e/ou módulo de controle de voltagem que é isolado a partir dos contatos de paciente (por exemplo, anodos e catodos). o módulo de realimentação pode ser isolado por um transistor a partir dos contatos de paciente; corrente de realimentação e/ou medições de controle de voltagem podem ser realizadas no transistor em vez de no contato de paciente (por exemplo, catodo). patent abstract: "electrotransport drug release current control". devices, systems and methods for controlling the application of current and / or voltage to release drug from patient contacts of an electrotransport drug delivery device by indirectly controlling and / or monitoring the applied current without measuring directly from the catheter of the terminal. patient. in particular, electrotransport drug release systems including constant current release systems having a feedback current and / or voltage control module that are isolated from patient contacts (e.g., anodes and cathodes). the feedback module may be isolated by a transistor from the patient contacts; Feedback current and / or voltage control measurements may be performed on the transistor rather than on the patient contact (eg cathode).

BIOSENSOR METER THAT DETECTS THE PROPER ADJUSTMENT OF THE ELECTRODES AND DISTINGUISHES SAMPLING AND CHECKING STRIPS.

UN CONTADOR DE BIOPERCEPCION (50) RECIBE UNA TIRA DE MUESTRA BIOMEDICA (10) QUE INCLUYE ELECTRODOS DE EXCITACION (14) Y SENTIDO (12) ELECTRICAMENTE AISLADOS O, ALTERNATIVAMENTE, UNA TIRA DE COMPROBACION. EL CONTADOR DE BIOPERCEPCION INCLUYE UN PRIMER Y SEGUNDO CONTACTOS (C, D) QUE ESTAN CONECTADOS POR UN ELECTRODO DE SENTIDO EN LA INSERCION DE UNA TIRA DE MUESTRA. UN CIRCUITO AMPLIFICADOR OPERACIONAL TIENE UNA PRIMERA Y SEGUNDA ENTRADA RESPECTIVAMENTE CONECTADAS AL PRIMER CONTACTO Y A UN POTENCIAL DE REFERENCIA, LA PRIMERA ENTRADA MANIFESTANDO EL POTENCIAL DE REFERENCIA COMO RESULTADO DE UNA RETROALIMENTACION EN EL AMPLIFICADOR OPERACIONAL. UN PROCESADOR (60) ESTA ACOPLADO AL SEGUNDO CONTACTO Y DETERMINA LA PRESENCIA DEL POTENCIAL DE REFERENCIA EN EL SEGUNDO CONTACTO CUANDO UN ELECTRODO DE SENTIDO INSERTADO CONECTA EL PRIMER Y SEGUNDO CONTACTOS. EL PROCESADOR TAMBIEN DISTINGUE ENTRE TIRAS DE MUESTRA Y DE COMPROBACION Y COMPRUEBA QUE HAYA UNA IMPEDANCIA ADECUADA ENTRE LOS ELECTRODOS DE SENTIDO Y EXCITACION DE UNA TIRA DE MUESTRA, PERMITIENDO ASI LA OPERACION DEL CONTADOR DE BIOPERCEPCION EN LA DOSIFICACION DE LA TIRA DE MUESTRA. A BIOPERCEPTION COUNTER (50) RECEIVES A BIOMEDICAL SAMPLE STRIP (10) THAT INCLUDES EXCITATION ELECTRODES (14) AND SENSE (12) ELECTRICALLY ISOLATED OR, ALTERNATIVELY, A CHECK STRIP. THE BIOPERCEPTION COUNTER INCLUDES A FIRST AND SECOND CONTACTS (C, D) THAT ARE CONNECTED BY A SENSE ELECTRODE IN THE INSERTION OF A SAMPLE STRIP. AN OPERATIONAL AMPLIFIER CIRCUIT HAS A FIRST AND SECOND ENTRY RESPECTIVELY CONNECTED TO THE FIRST CONTACT AND TO A POTENTIAL OF REFERENCE, THE FIRST ENTRY MANIFESTING THE REFERENCE POTENTIAL AS A RESULT OF A FEEDBACK IN THE OPERATIONAL AMPLIFIER. A PROCESSOR (60) IS COUPLED TO THE SECOND CONTACT AND DETERMINES THE PRESENCE OF THE REFERENCE POTENTIAL IN THE SECOND CONTACT WHEN AN INSERTED SENSE ELECTRODE CONNECTS THE FIRST AND SECOND CONTACTS. THE PROCESSOR ALSO DISTINGUISHES BETWEEN SAMPLING AND CHECKING STRIPS AND CHECKS ...

Current control for electrotransport drug delivery

Devices, systems and methods for controlling the application of current and/or voltage to deliver drug from patient contacts of an electrotransport drug delivery device by indirectly controlling and/or monitoring the applied current without directly measuring from the cathode of the patient terminal. In particular, described herein are electrotransport drug delivery systems including constant current delivery systems having a feedback current and/or voltage control module that is isolated from the patient contacts (e.g., anodes and cathodes). The feedback module may be isolated by a transistor from the patient contacts; feedback current and/or voltage control measurements may be performed at the transistor rather than at the patient contact (e.g., cathode).

Fill indicator rollers for printer trays

Example feed trays for a printer are disclosed. In one example, the feed tray includes a support surface to support print media, and a guide wall coupled to the support surface. The support surface and the guide wall define a feed path for the print media into the printer, and the guide wall is movable along the support surface. In addition, the feed tray includes a fill indicator comprising a roller mounted to the guide wall that extends into the feed path. The roller is to rotate about an axis of rotation that is perpendicular to the feed path.

Medical scanning assembly with variable image capture and display

A scanned beam imaging system including a housing suitable for insertion into a body and a radiation source configured to direct a beam of radiation into or through the housing and onto an area within the body. The scanned beam imaging system further includes an adjustable element inside the housing and positioned to reflect the beam of radiation or to receive the beam of radiation therethrough, wherein the adjustable element is physically adjustable to vary a property of the beam of radiation that is reflected thereby or received therethrough. The scanned beam imaging system further includes a collector configured to receive radiation returned from the area within the body.

Self-test for analgesic product

Electrotransport drug delivery devices, system and methods of using configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices/systems may include an off-current module to determine that any current (e.g., which may be inferred by measuring potential difference between the anode and cathode of the device) flowing between the anode and cathode is below a threshold value when the device is not supposed to be delivering drug, thereby preventing unintended delivery of drug and/or alerting a user that unintended delivery of drug may occur.

Bar linkage for friction-fit range reducer

A bar linkage for a pipe coupling can include a first bar configured to span two end rings of the pipe coupling; a second bar configured to span the two end rings of the pipe coupling; and a single tensioner extending through each of the first bar and the second bar and joining the first bar to the second bar along an axis of the bar linkage in an assembled condition of the bar linkage, the tensioner configured to draw the first bar towards the second bar, the first bar and the second bar able to be angled with respect to each other and with respect to the axis of the pipe coupling in a tightened condition of the pipe coupling when viewing the bar linkage from the top when the pipe coupling couples pipes of unequal diameter.

Valve body with bypass

A valve body with an integral bypass includes a primary valve body portion defining a primary bore extending through the primary valve body portion from a primary upstream end to a primary downstream end, the primary bore defining an axis, the primary bore including a primary upstream bore extending through the primary upstream end and a primary downstream bore extending through the primary downstream end, the primary valve body portion configured to house a valve member between the primary upstream bore and the primary downstream bore; and the bypass seamlessly integrated with the primary valve body portion, the bypass defining a bypass bore, the bypass bore including a bypass upstream bore and a bypass downstream bore, the bypass including a bypass valve body disposed between the bypass upstream bore and the bypass downstream bore.

Embolic protection device with filter membrane comprising tubular members

Embolic protection filtering devices and methods for making and using the same. An example filtering device includes a filter wire and a filter coupled to the filter wire. The filter can include a filter loop (16) and a filter membrane (22) coupled to the filter loop. A plurality of tubular members (32) may be coupled to the filter membrane. This allows a filter retaining shaft (34) to extend through tubular member (32) that holds filter (16) in the collapsed configuration.

Valve body with integral bypass

A valve body with an integral bypass includes a primary valve body portion defining a primary internal surface, the primary internal surface defining a primary bore extending through the primary valve body portion from a primary upstream end to a primary downstream end; and the bypass seamlessly integrated with the primary valve body portion, the bypass defining a bypass internal surface, the bypass internal surface defining a bypass bore, the bypass bore comprising a bypass upstream bore and a bypass downstream bore, the bypass upstream bore extending through the primary upstream end of the primary valve body portion, the bypass downstream bore extending through the primary downstream end of the primary valve body portion, the bypass internal surface seamlessly intersecting the primary internal surface at the primary upstream end and the primary downstream end.

Communication generation in complex computing networks

This disclosure is directed to communication generation by traversing routes of a graph in a complex computing network. The communication generation is used for determining whether certain input data has certain desired data attributes.

Coupling gasket and bar linkage for friction-fit range reducer

A seal for a pipe coupling can include an outer gasket defining a radially inner surface defining a plurality of grooves; and an inner gasket separably joined to the outer gasket and defining a radially outer surface, the radially outer surface defining a plurality of ridges extending radially outward and including: a first ridge, each of first and second side surfaces of the first ridge angled in cross-section with respect to a radial direction of the inner gasket towards a first axial end of the inner gasket when in an uncompressed state; and a second ridge, each of first and second side surfaces of the second ridge angled in cross-section with respect to the radial direction towards a second axial end of the inner gasket when in the uncompressed state; wherein the radially outer surfaces of the inner and outer gaskets contact each other.

Biodetektionsinstrument und auswertungsverfahren

Floating on the wire filter wire

Embolic protection filtering devices and methods for making and using the same. An example filtering device includes a filter wire, a filter slidable over the filter wire, and a filter membrane coupled to the filter frame. The filter wire includes a plurality of stops. The filter includes a proximal tubular member, a distal tubular member, and a connecting tubular member extending between the proximal tubular member and the distal tubular member.

Egg hatching and larvae separation device and method

Slide gate assembly

A slide gate includes a gate body defining a first gate face and a second gate face; and an integral gate seal integrally formed with the first gate face, the integral gate seal comprising an additive material additively deposited on the first gate face, the integral gate seal defining a gate seating face.

Sample pooling assay

Provided herein are compositions and methods for detecting nucleic acids in pooled samples.

Egg hatching and larvae separation devices and methods

A device including a fluid-tight container, wherein the fluid-tight container includes a base having a first portion and a second portion; at least one wall enclosing the base and coupled to the base to form a fluid-tight seal; wherein the first portion of the base comprises a first color and defines a recess; and wherein the second portion of the base comprises a second color darker than the first color.