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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 8. Отображено 8.
08-12-2016 дата публикации

DRUG-ELUTING DEVICE FOR PROPHYLAXIS OR TREATMENT OF A DISEASE OR PATHOLOGY

Номер: US20160354522A1
Принадлежит:

The invention disclosed herein generally relates to particular intravascular drug-eluting delivery devices and methods for manufacture and use in either the prophylaxis or treatment of a disease or pathology. In one aspect, the intravascular device may comprise a verapamil eluting stent with polymeric coating designed for the controlled release of a vasodilating drug in the prophylactic or remedial treatment of cerebral vasospasm. 1. A drug eluting prosthesis for the controlled release of one or more drugs in the remedial or prophylactic treatment of a disease , the prosthesis comprising:a prosthesis body having an inner surface and an outer surface;at least one layer of biodegradable polymeric material bonded to at least one surface of the prosthesis body, the polymeric material being capable of absorbing and releasing the one or more drugs;at least one drug dispersed within at least one layer of the polymeric material;wherein the controlled release comprises control over initiation time for drug elution, control over duration time for drug elution, and control over quantity of drug being eluted.2. The prosthesis of claim 1 , wherein the prosthesis is a drug eluting stent or scaffold having a lumen and capable of radial expansion claim 1 , the prosthesis body formed from a material comprising metals claim 1 , ceramics claim 1 , polymers claim 1 , or combinations thereof.3. The prosthesis of claim 2 , wherein the material forming the prosthesis body is at least partially biodegradable.4. The prosthesis of claim 3 , wherein the material comprises nitinol.5. The prosthesis of claim 3 , wherein at least a first drug is contained within a polymeric base layer bonded to at least one surface of the prosthesis body.6. The prosthesis of claim 5 , comprising a second polymeric layer that does not comprise a drug claim 5 , the second polymeric layer built upon the base layer claim 5 , and permitting the initiation of drug release from the base layer to be delayed.7. The ...

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19-04-2018 дата публикации

DRUG-ELUTING DEVICE FOR PROPHYLAXIS OR TREATMENT OF A DISEASE OR PATHOLOGY

Номер: US20180104386A1
Принадлежит:

The invention disclosed herein generally relates to particular intravascular drug-eluting delivery devices and methods for manufacture and use in either the prophylaxis or treatment of a disease or pathology. In one aspect, the drug eluting prosthesis is implanted into a patient's blood vessel upstream of a disease site. 1. A therapeutic method , for the remedial or prophylactic treatment of a disease , the method comprising: a prosthesis body having an inner surface and an outer surface;', 'at least one layer of biodegradable polymeric material bonded to at least one surface of the prosthesis body, the polymeric material being capable of absorbing and releasing one or more drugs; and', 'at least one drug dispersed within at least one layer of the polymeric material;, "implanting a drug eluting prosthesis into a patient's blood vessel upstream of a disease site, the drug eluting prosthesis comprising:"}avoiding the critical blood vessel branches at the disease site; andreleasing a drug to match the clinical manifestations.2. The method of claim 1 , wherein the prosthesis is a drug eluting stent or scaffold having a lumen and capable of radial expansion claim 1 , the prosthesis body formed from a material comprising metals claim 1 , ceramics claim 1 , polymers claim 1 , or combinations thereof.3. The method of claim 2 , wherein the material forming the prosthesis body is at least partially biodegradable.4. The method of claim 3 , wherein the material comprises nitinol.5. The method of claim 3 , wherein at least a first drug is contained within a polymeric base layer bonded to at least one surface of the prosthesis body.6. The method of claim 5 , comprising a second polymeric layer that does not comprise a drug claim 5 , the second polymeric layer built upon the base layer claim 5 , and permitting the initiation of drug release from the base layer to be delayed.7. The method of claim 5 , comprising a second polymeric layer that comprises at least one drug claim 5 , ...

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23-07-2020 дата публикации

BIOABSORBABLE FLOW DIVERTING SCAFFOLD

Номер: US20200229954A1
Принадлежит: fluid biotech inc.

This disclosure relates to scaffolds made of a braid of bioabsorbable polymeric fibers for implantation within a lumen of a mammalian body and, in particular, to such scaffolds that are configured to divert blood flow from a pathology associated with a blood vessel. 1. A device , comprising a resiliently deformable tubular body for positioning in a body lumen defined by a body wall , the tubular body comprising a braid of interwoven bioabsorbable polymeric fibers , wherein the tubular body comprises at least 38 polymeric fibers.2. The device of claim 1 , wherein claim 1 , when the device is in an expanded formation claim 1 , the braid has a porosity in the range of about 5% to about 80%.3. The device of claim 1 , wherein claim 1 , when the device is in an expanded formation claim 1 , the braid has a porosity in the range of about 60% to about 80%.4. A device claim 1 , comprising a resiliently deformable tubular body for positioning in a body lumen defined by a body wall claim 1 , the tubular body comprising a braid of interwoven bioabsorbable polymeric fibers claim 1 , wherein claim 1 , when the device is in an expanded formation claim 1 , the braid has a porosity in the range of about 60% to about 80%.5. The device of claim 4 , wherein the tubular body comprises at least 38 polymeric fibers.6. The device of claim 1 , wherein the bioabsorbable polymeric fibers have a diameter in the range of about 30 μm to about 80 μm.7. The device of claim 1 , wherein tubular body further comprises a visualization aid.8. The device of claim 7 , wherein the visualization aid comprises at least one wire comprising a radio-opaque material claim 7 , wherein each wire is interwoven with the plurality of bioabsorbable polymeric fibers to form part of the braid.9. The device of claim 1 , wherein the tubular body comprises means for facilitating and/or maintaining radial and/or axial expansion of the tubular body in the body lumen.10. The device of claim 9 , wherein the means for ...

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06-11-2016 дата публикации

Drug-eluting device for prophylaxis or treatment of a disease or pathology

Номер: CA2929926A1
Принадлежит: Fluid Biotech Inc

The invention disclosed herein generally relates to particular intravascular drug-eluting delivery devices and methods for manufacture and use in either the prophylaxis or treatment of a disease or pathology. In one aspect, the intravascular device may comprise a verapamil eluting stent with polymeric coating designed for the controlled release of a vasodilating drug in the prophylactic or remedial treatment of cerebral vasospasm

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19-09-2019 дата публикации

Bioabsorbable flow diverting scaffold

Номер: CA3068075A1
Принадлежит: Fluid Biotech Inc

This disclosure relates to scaffolds made of a braid of bioabsorbable polymeric fibers for implantation within a lumen of a mammalian body and, in particular, to such scaffolds that are configured to divert blood flow from a pathology associated with a blood vessel.

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21-07-2020 дата публикации

Bioabsorbable flow diverting scaffold

Номер: CA3068075C
Принадлежит: Fluid Biotech Inc

This disclosure relates to scaffolds made of a braid of bioabsorbable polymeric fibers for implantation within a lumen of a mammalian body and, in particular, to such scaffolds that are configured to divert blood flow from a pathology associated with a blood vessel.

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28-02-2024 дата публикации

Bioabsorbable flow diverting scaffold

Номер: EP3765106B1
Принадлежит: Fluid Biotech Inc

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12-10-2023 дата публикации

Bioabsorbable flow diverting scaffold and methods for its use

Номер: US20230321325A1
Принадлежит: Fluid Biomed Inc

This disclosure relates to scaffolds made of a braid of bioabsorbable polymeric fibers for implantation within a lumen of a mammalian body and, in particular, to such scaffolds that are configured to divert blood flow from a pathology associated with a blood vessel.

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