14-03-2013 дата публикации
Номер: US20130065900A1
The invention provides a compound of the formula (1): 3. A compound according to claim 1 , or a salt claim 1 , N-oxide or tautomer thereof claim 1 , wherein Ar is selected from optionally substituted phenyl and optionally substituted five and six membered heteroaryl groups containing one claim 1 , two or three heteroatom ring members selected from O claim 1 , N and S.4. A compound according to claim 3 , or a salt claim 3 , N-oxide or tautomer thereof claim 3 , wherein Ar is optionally substituted phenyl.5. A compound according to claim 1 , or a salt claim 1 , N-oxide or tautomer thereof claim 1 , wherein each Ris independently selected from a group Rconsisting of halogen; cyano; nitro; a monocyclic carbocyclic or heterocyclic group having from 3 to 10 ring members claim 1 , of which 0 claim 1 , 1 claim 1 , 2 claim 1 , 3 or 4 are heteroatom ring members selected from O claim 1 , N and S and oxidised forms thereof claim 1 , the carbocyclic or heterocyclic group being and optionally substituted with one or more substituents R; or{'sup': a1', 'b1, 'a group R—R;'}{'sup': a1', '1a', '2a', '2a', '1a', '1a', '2a', '1a', 'c1', 'c1', 'c1, 'sub': 2', '2', '2, 'Ris a bond, O, CO, XC(X), C(X)X, XC(X)X, S, SO, SO, NR, SONRor NRSO;'}{'sup': 'b1', 'claim-text': hydrogen;', {'sup': '14a', 'a carbocyclic and heterocyclic group having from 3 to 10 ring members, of which 0, 1, 2, 3 or 4 are heteroatom ring members selected from O, N and S and oxidised forms thereof, the carbocyclic or heterocyclic group being optionally substituted with one or more substituents R;'}, {'sub': 1-8', '1-8', '1-8', '2, 'sup': 14a', 'c1', '1a', '2a', '2a', '1a', '1a', '2a', '1a, 'an acyclic Chydrocarbyl group optionally substituted with one or more substituents selected from hydroxy; oxo; halogen; cyano; nitro; carboxy; amino; mono- or di-Cnon-aromatic hydrocarbylamino; and monocyclic carbocyclic and heterocyclic groups having from 3 to 10 ring members, of which 0, 1, 2, 3 or 4 are heteroatom ring members ...
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