PROCESS FOR THE PREPARATION OF MONODISPERSE POLYMER PARTICLES

A process for the preparation of monodisperse polymer particles which are formed by contacting monomers with aqueous dispersions comprising monodisperse swellable seed polymers/oligomers, and initiating polymerization in the presence of a steric stabilizer. The resulting swollen seed particles are characterized by the particle mode diameter. 122-. (canceled)23. A process for the preparation of monodisperse polymer particles comprising:1) preparing monodisperse swellable seed particles by emulsion polymerization, wherein an anionic surfactant is employed as emulsifier under substantially oxygen-free conditions;wherein said seed particles are non-oligomeric:{'sup': '−2', '(a1) contacting said non-oligomeric seed particles with an aqueous dispersion comprising an organic compound with a molecular weight below 5000 Dalton and a water solubility at 25° C. of less than 10g/L; the anionic surfactant; and optionally an organic solvent in which said organic compound is soluble;'}(b1) allowing said organic compound to diffuse into said non-oligomeric seed particles; and(c1) contacting the aqueous dispersion of non-oligomeric seed particles with a monomer which is at least ten times more water soluble than said organic compound; or wherein said seed particles are oligomeric:(a2) contacting said oligomeric seed particles with an aqueous dispersion comprising the anionic surfactant; and(b2) contacting the aqueous dispersion of oligomeric seed particles with a monomer;2) if required adding a water-soluble steric stabilizer, if required adding a porogen, and if required adding a polymerization initiator; and3) initiating polymerization of said monomer in an aqueous dispersion containing a steric stabilizer in continuous phase.241. A process of wherein in step ) the oxygen content of the aqueous phase is between 0 and 5 ppm or is between 0 and 3 ppm.25. A process of wherein the oxygen content is between 0 and 2 ppm or between 0 and 1 ppm.26. A process of wherein said monomer ...

PARTICLES

A coated magnetic particle comprising an optionally porous magnetic polymer particle of a matrix polymer, said polymer particle having on a surface and/or in the pores thereof superparamagnetic crystals, said coated particle having a coat formed of a coating polymer, wherein said coated magnetic particle is essentially non-autofluorescent. 131-. (canceled)32. A method of polymerization of coated monomers comprising:catalysing the polymerisation of coating monomers which comprise at least one epoxide using one or more superparamagnetic crystals.33. The method of claim 32 , wherein the epoxide is an epichlorohydrin claim 32 , epibromohydrin claim 32 , isopropylglycidyl ether claim 32 , butyl glycidyl ether claim 32 , allylglycidyl ether claim 32 , 1 claim 32 ,4-butanediol diglycidyl ether (1 claim 32 ,4-bis (2 claim 32 ,3-epoxypropoxy) butane) claim 32 , neopentylglycol diglycidyl ether claim 32 , ethylene glycol diglycidyl ether claim 32 , glycerol diglycidyl ether claim 32 , glycidol claim 32 , and glycidyl methacrylate claim 32 , ethyl hexyl glycidylether claim 32 , methyl glycidylether claim 32 , glycerol propoxylate triglycidylether claim 32 , poly(propylene glycol) diclycidylether claim 32 , 1 claim 32 ,3 butanediol diglycidylether claim 32 , tert butyl glycidylether claim 32 , 1 claim 32 ,4 cyclohexanedimethanol diglycidyl ether claim 32 , diethylene glycol diglycidyl ether claim 32 , dodecyl glycidylether claim 32 , O-(2 claim 32 ,3 epoxypropyl)-O′-methylpolyethylene glycol glydidylether claim 32 , glycidyl tetrafluoroethyl ether claim 32 , 1 claim 32 ,6 hexanediol diglycidylether claim 32 , octyl glycidylether claim 32 , decyl glycidylether claim 32 , poly(epichlorohydrin-co-ethylene oxide-co-allyl glycidylether) claim 32 , polyethylene glycol diglycidyl ether claim 32 , trimethylolethane triglycidylether claim 32 , trimethylolpropane claim 32 , triglycidylether claim 32 , tert-butyldimethylsilyl glycidylether claim 32 , 1 claim 32 ,2-epoxybutane claim 32 , 1 ...

PROCESS FOR THE PREPARATION OF MONODISPERSE POLYMER PARTICLES

A process for the preparation of monodisperse polymer particles which are formed by contacting monomers with aqueous dispersions comprising monodisperse swellable seed polymers/oligomers, and initiating polymerization in the presence of a steric stabilizer. The resulting swollen seed particles are characterized by the particle mode diameter. 1. A process for the preparation of monodisperse polymer particles having diameters of 1μ to 6μ , the process comprising:forming an aqueous dispersion comprising monodisperse swellable seed particles and an anionic surfactant;contacting the aqueous dispersion with a monomer selected from the group consisting of acrylic monomers, methacrylate monomers and vinyl monomers selected from the group consisting of styrene, divinylbenzene (DVB), ethyl vinyl benzene, vinyl pyridine, aminostyrene, methyl-styrene, dimethylstyrene, ethyl styrene, ethyl-methyl-styrene, p-chlorostyrene and 2,4-dichlorostyrene;allowing the monomer to diffuse into the seed particles to form an aqueous dispersion of swollen seed particles; andinitiating polymerization of the monomer in the aqueous dispersion of swollen seed particles;wherein the aqueous dispersion of swollen seed particles further comprises a polyvinylpyrrolidone.2. The process of claim 1 , wherein the polyvinylpyrrolidone has an average molecular weight of 10 kD to 2000 kD.3. The process of claim 1 , wherein the monodisperse swellable seed particles are monodisperse swellable seed oligomer particles.4. The process of claim 1 , wherein the monomer comprises at least 30% by weight divinyl benzene.5. The process of claim 1 , wherein the anionic surfactant is sodium dodecyl sulfate.6. A process for the preparation of monodisperse polymer particles claim 1 , the process comprising:forming an aqueous dispersion comprising monodisperse swellable seed particles and an anionic surfactant;contacting the aqueous dispersion of seed particles with a monomer;allowing the monomer to diffuse into the seed ...

PARTICLES

A coated magnetic particle comprising an optionally porous magnetic polymer particle of a matrix polymer, said polymer particle having on a surface and/or in the pores thereof superparamagnetic crystals, said coated particle having a coat formed of a coating polymer, wherein said coated magnetic particle is essentially non-autofluorescent. 1. A coated magnetic particle comprising an optionally porous magnetic polymer particle of a matrix polymer , said polymer particle having on a surface and/or in the pores thereof superparamagnetic crystals , said coated particle having a coefficient of variation (CV) of less than 10% and having a coat formed of a coating polymer , wherein said coated magnetic particle is essentially non-autofluorescent.2. A coated magnetic particle as claimed in having a level of autofluorescence corresponding to a difference in the Mean Grey Value (ΔMGV) at an excitation wavelength of 450±25 nm for an exposure time of 500 ms or 600 ms of less than 600.3. A coated magnetic particle as claimed in having a level of autofluorescence corresponding to a difference in the Mean Grey Value (ΔMGV) at an excitation wavelength of 450±25 nm for an exposure time of 500 ms or 600 ms of less than 300.4. A coated magnetic particle as claimed in any one of to being essentially free of conjugated delocalized electron systems (except those within benzene rings).5. A coated magnetic particle as claimed in any one of to wherein said coating polymer is formed from at least one epoxide.6. A coated magnetic particle as claimed in wherein said coating polymer is formed from at least two epoxides.7. A coated magnetic particle as claimed in wherein the epoxides are selected from epichlorohydrin claim 6 , epibromohydrin claim 6 , isopropylglycidyl ether claim 6 , butyl glycidyl ether claim 6 , allylglycidyl ether claim 6 , 1 claim 6 ,4-butanediol diglycidyl ether (1 claim 6 ,4-bis(2 claim 6 ,3-epoxypropoxy)butane) claim 6 , ethylhexylglycidylether claim 6 , methyl ...

PARTICLES

A coated magnetic particle comprising an optionally porous magnetic polymer particle of a matrix polymer, said polymer particle having on a surface and/or in the pores thereof superparamagnetic crystals, said coated particle having a coat formed of a coating polymer, wherein said coated magnetic particle is essentially non-autofluorescent. 131-. (canceled)32. A composition comprising a non-autofluorescent coated magnetic polymer particle comprising:a porous matrix polymer particle comprising superparamagnetic crystals on the surface and in the pores thereof, wherein majority of the superparamagnetic crystals are within pores of the porous matrix polymer particle, and wherein the porous matrix polymer particle is essentially free of conjugated delocalised electron systems other than those found in benzene rings; anda coat of a coating polymer wherein the coating polymer is formed by the polymerization of coating monomers wherein the coating monomers are essentially free of conjugated delocalised electron systems other than those found in benzene rings, wherein the coated magnetic polymer particle is essentially non-autofluorescent,wherein the coated magnetic polymer particle has a coefficient of variation (CV) of less than 10%, andwherein the coated magnetic polymer particle has a level of autofluorescence corresponding to a difference in the Mean Grey Value (ΔMGV) at an excitation wavelength of 450±25 nm for an exposure time of 500 ms or 600 ms of less than 600.33. The non-autofluorescent coated magnetic polymer particle of claim 32 , further surface functionalized with a functional group essentially free of conjugated delocalised electron systems other than those found in benzene rings.34. The non-autofluorescent coated magnetic polymer particle of claim 33 , wherein the functional group is selected from a sulphonic acid claim 33 , a carboxylic acid claim 33 , an amine claim 33 , or an epoxy group.35. The non-autofluorescent coated magnetic polymer particle of ...

PROCESS FOR THE PREPARATION OF MONODISPERSE POLYMER PARTICLES

A process for the preparation of monodisperse polymer particles which are formed by contacting monomers with aqueous dispersions comprising monodisperse swellable seed polymers/oligomers, and initiating polymerization in the presence of a steric stabilizer. The resulting swollen seed particles are characterized by the particle mode diameter.

Process for the preparation of monodisperse polymer particles

Process for the preparation of functionalized polymer particles

A process for the preparation of amine-functionalized vinyl polymer particles which process comprises suspension polymerizing aminostyrene together with at least one other vinylic monomer and optionally a crosslinking agent.

Process for the preparation of monodisperse polymer particles

A process for the preparation of monodisperse polymer particles which are formed by contacting monomers with aqueous dispersions comprising monodisperse swellable seed polymers/oligomers, and initiating polymerization in the presence of a steric stabilizer. The resulting swollen seed particles are characterized by the particle mode diameter.

Process for the preparation of functionalised polymer particles

A process for the preparation of amine-functionalized vinyl polymer particles which process comprises suspension polymerizing minostyrene together with at least one other vinylic monomer and optionally a crosslinking agent.

Verfahren für die herstellung von monodispergierten polymerteilchen

Process for the preparation of monodisperse polymer particles

A process for the preparation of monodisperse polymer particles which are formed by contacting monomers with aqueous dispersions comprising monodisperse swellable seed polymers/oligomers, and initiating polymerisation in the presence of a steric stabiliser. The resulting swollen seed particles are characterised by the particle mode diameter.

Particles

The present invention relates to a use of superparamagnetic crystals to catalyse the polymerisation of coating monomers which comprise at least one epoxide.

Process for the preparation of monodisperse polymer particles

Process for the preparation of functionalised polymer particles

The invention provides a process for the preparation of amine-functionalised vinyl polymer particles which process comprises suspension polymerizing aminostyrene together with at least one other vinylic monomer and optionally a crosslinking agent.

Process for the preparation of monodisperse polymer particles

A process for the preparation of monodisperse polymer particles which are formed by contacting monomers with aqueous dispersions comprising monodisperse swellable seed polymers/oligomers, and initiating polymerisation in the presence of a steric stabiliser. The resulting swollen seed particles are characterised by the particle mode diameter.

Process for the preparation of monodisperse polymer particles

Process for the preparation of monodisperse polymer particles

A process for the preparation of monodisperse polymer particles which are formed by contacting monomers with aqueous dispersions comprising monodisperse swellable seed polymers/oligomers, and initiating polymerisation in the presence of a steric stabiliser. The resulting swollen seed particles are characterised by the particle mode diameter.

Verwendung von superparamagnetischen kristallen zur katalyse der polymerisation von epoxid- monomeren

Partikeln

Verfahren zur herstellung von oberflächenfunktionalisierten polymerteilchen

Verfahren für die herstellung von monodispergierten polymerteilchen