Targeted NTRK fusion gene compound and preparation method and application thereof

The invention relates to the technical field of tumor phenomenon diagnosis and treatment, in particular to a compound of a targeted NTRK fusion gene and a preparation method and application of the compound, the compound is a conjugate of lalotinib, a chelating agent DOTA and radioactive metal nuclide, and the compound can be specifically taken by tumor cells and can be used for treating tumor cells. The NTRK fusion gene positive tumor is developed and screened by using the marked radioactive metal nuclide 68Ga, and then is treated by using the marked radioactive metal nuclide 177Lu, so that the tumor diagnosis and treatment can be combined into a whole, the treatment effect can be evaluated, and meanwhile, the number of radiopharmaceutical injection times is reduced, so that the radiation dose of a patient is reduced to a certain extent; according to the compound, tumor diagnosis and treatment can be combined into a whole, the treatment effect can be evaluated, meanwhile, the number of ...