30-06-2010 дата публикации
Номер: CN0101756916A
Автор:
CHANG YANYAN,
HE XIAYI,
HOU PENG,
LI WEI,
LIU DONG,
SHI HEPENG,
ZENG LIJUN,
ZHOU JINMEI,
YANYAN CHANG,
XIAYI HE,
PENG HOU,
WEI LI,
DONG LIU,
HEPENG SHI,
LIJUN ZENG,
JINMEI ZHOU
Принадлежит:
The invention provides a preparation method of double-layer sustained release tablets containing folic acid, calcium carbonate, vitamin B12 and vitamin B6, and the combination is a double-layered tablet, wherein, vitamin B6 is a slow release layer and the folic acid is a quick release layer. In the method, vitamin B6 is prepared into the slow release layer and the folic acid and the like are prepared into the quick release layer, and then the two layers are pressed into the double-layered tablets. The method solves the common problem of splinters owing to long-time placement of the double-layered tablets; and the prepared compound vitamin B6 sustained release tablets has good appearance, tight combination between an upper layer and a lower layer, wherein, the swelling rate and the swelling degree of the two layers are consistent under the influence of the external humiture, which can always maintain good appearance and release speed. The compound vitamin B6 sustained release tablets have ...
Подробнее