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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 3. Отображено 3.
04-07-2023 дата публикации

Method and device for detecting copy number variation and medium

Номер: CN116386718A
Автор: ZHONG YING, ZHANG QIANQIAN, HU JINGJING, LI NING, LIU HUITAO, XIN ZHONGTAO
Принадлежит:

The invention relates to a method and equipment for detecting copy number variation and a medium. The method comprises the following steps: comparing preprocessed sequencing data with sequencing data of a reference genome so as to obtain comparison result data, the sequencing data being obtained by an amplicon sequencing technology; aiming at the comparison result data, filtering out the sequencing data meeting a preset filtering condition; on the basis of comparison result data left by filtering, obtaining the overall uniformity of an amplicon sequencing region so as to determine a stably amplified targeted analysis region; constructing a control set baseline based on the sequencing depth of the stably amplified targeted analysis region; and generating a detection result about the copy number variation of the to-be-detected sample based on the breakpoint position of the copy number variation of the to-be-detected sample determined by the prediction model and the constructed contrast set ...

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Номер записи: 1
23-06-2023 дата публикации

Primer group, kit and method for detecting mutation types of various disease-related genes

Номер: CN116287198A
Автор: ZHANG QIANQIAN, ZHONG YING, XIN ZHONGTAO, LI XIANG, LI NING, HU JINGJING
Принадлежит:

The invention relates to a primer group, a kit and a method for detecting various disease-related gene mutation types. According to the invention, genetic deafness, thalassemia and spinal muscular atrophy related gene mutation types can be detected at the same time, clinical common known pathogenic SNP, INDEL and copy number variation can be detected at the same time only through one tube and one experiment, and the detection efficiency of the three diseases and the standardization degree of clinical detection are remarkably improved. The primer group comprises: 1) primers for detecting a gene mutation type of hereditary hearing loss as shown in SEQ ID NO: 1-30; (2) a primer for detecting the gene mutation type of thalassemia, wherein the primer is shown as SEQ ID NO: 31-340; 3) primers for detecting the gene mutation type of the spinal muscular atrophy, wherein the primers are shown as SEQ ID NO: 341-350; and 4) primers for detecting the beta-actin housekeeping gene, wherein the primers ...

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Номер записи: 2
14-09-2011 дата публикации

Method for obtaining influenza virus nucleic acid in influenza sample and special primer thereof

Номер: CN0102180927A
Автор: WUCHUN CAO, WEI LIU, MAOTI WEI, LEI ZHANG, ZHONGTAO XIN, XIAOAI ZHANG, HAO LI, MAIQUAN MA, CAO WUCHUN, LIU WEI, WEI MAOTI, ZHANG LEI, XIN ZHONGTAO, ZHANG XIAOAI, LI HAO, MA MAIQUAN
Принадлежит:

The invention discloses a method for obtaining nucleic acid of influenza virus in an influenza sample and a special primer thereof. A primer pair for amplifying the nucleic acid of the influenza virus consists of a primer as shown in a sequence 9 in a sequence table and a primer as shown in a sequence 10 in the sequence table. The method for obtaining influenza viral genome DNA (deoxyribonucleic acid) comprises the following steps: based on the total RNA (ribonucleic acid) of a sample infected by influenza virus as a template, carrying out RT-PCR (reverse transcription-polymerase chain reaction) amplification with the primer pair so as to obtain a RT-PCR amplification product, namely the nucleic acid of the influenza virus. Through the method in the patent, virus separation is not carried out and the genome of the influenza virus is amplified directly from a nucleic acid extractive of a clinic sample, thereby greatly simplifying the program of influenza virus gene research and saving experiment ...

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Номер записи: 3