Pharmaceutical composition for preventing and treating atherosclerosis

The invention relates to a medicine composition containing arecoline, ligustrazine and paeonol, and application thereof to preparation of medicine resisting atherosclerosis. The medicine composition is suitable for preventing and treating the atherosclerosis and cardiovascular diseases related to the atherosclerosis.

Sulfonamides compound for inhibiting carbonic anhydrase II and synthesis method and application thereof

The invention relates to a sulfonamides compound for inhibiting carbonic anhydrase II and a synthesis method and an application thereof. The compound has the structure as shown in the specification. The invention features economical and reasonable synthetic route and high utilization of resources. The synthesis method is simple and easy to carry out and is more suitable for large-scale industrialized production. With human carbonic anhydrase II (Human Carbonic Anhydrase II, hCA II) expressed by procaryotic cell as an enzyme source, the invention establishes an in-vitro carbonic anhydrase inhibitor screening model. In addition, the compound of the invention has inhibitive effect on activity of the human carbonic anhydrase II.

Bactericide composition for preventing and controlling alternaria alternata and application thereof

The invention discloses a bactericide composition for preventing and controlling alternaria alternata. The bactericide composition comprises iprodione and thiram serving as active ingredients. The composition of the invention can be used for preventing and controlling the alternaria alternata and crop pests of fruit trees, vegetables and the like and has the advantages of wide application range, low cost and good effect.

Improved method for preparing liposome by using ammonium sulfate gradient method

The invention relates to the field of a pharmaceutical preparation, in particular to an improved method for preparing liposome by using an ammonium sulfate gradient method. The method for actively loading medicines after preparing the empty liposome solution comprises the following steps: adding water solution of a pH regulating agent, water solution of osmotic pressure regulating agent or water into the empty liposome solution, then adding medicines or water solution of medicines, and carrying out active medicine loading. The preparation method can realize active medicine loading simply without needing trivial and time-consuming technique steps or expensive particular equipment, thus greatly simplifying production technique, improving production efficiency and reproducibility and simultaneously and greatly reducing production cost.

A traditional Chinese medicine preparation with functions of immunological regulation for anti-chemical damage

Improved method for preparing liposome by using ammonium sulfate gradient method

The invention relates to the field of a pharmaceutical preparation, in particular to an improved method for preparing liposome by using an ammonium sulfate gradient method. The method for actively loading medicines after preparing the empty liposome solution comprises the following steps: adding water solution of a pH regulating agent, water solution of osmotic pressure regulating agent or water into the empty liposome solution, then adding medicines or water solution of medicines, and carrying out active medicine loading. The preparation method can realize active medicine loading simply without needing trivial and time-consuming technique steps or expensive particular equipment, thus greatly simplifying production technique, improving production efficiency and reproducibility and simultaneously and greatly reducing production cost.

Oxadiazon and mefenacet mixed herbicide

The invention discloses an oxadiazon and mefenacet mixed herbicide which simultaneously comprises the effective ingredients of oxadiazon and mefenacet. The herbicide has the characteristics of broad spectrum, high efficiency, safety and low toxicity and achieves the effect of weeding at one time in paddy fields.

Citrate lithodialyzate and its preparation method

A calculus-dissolving liquor for treating calculosis in urinary system is mainly prepared from potassium citrate, sodium citrate and crystal sugar, as well as citric acid, magnetized distilled water,dihydrochlothiazide and belladonna, and features low cost, simple productive process, reliable curative effect and short course of treatment.

Sulfonamides compound for inhibiting carbonic anhydrase II and synthesis method and application thereof

The invention relates to a sulfonamides compound for inhibiting carbonic anhydrase II and a synthesis method and an application thereof. The compound has the structure as shown in the specification. The invention features economical and reasonable synthetic route and high utilization of resources. The synthesis method is simple and easy to carry out and is more suitable for large-scale industrialized production. With human carbonic anhydrase II (Human Carbonic Anhydrase II, hCA II) expressed by procaryotic cell as an enzyme source, the invention establishes an in-vitro carbonic anhydrase inhibitor screening model. In addition, the compound of the invention has inhibitive effect on activity of the human carbonic anhydrase II.

Method for absorbing and utilizing phosgene tail gas

The invention discloses a method for absorbing and utilizing phosgene tail gas. The method comprises the following steps: the phosgene tail gas generated in a phosgenation process (especially the phosgene tail gas generated in the phosgenation process with content of between 10 and 50 percent (V/V), such as the phosgene tail gas generated in the phosgenation process of diuron, chlortoluron and other products) is directly cooled and absorbed through a halohydrocarbon solvent, phosgene and partial hydrogen chloride in the phosgene tail gas are recovered to obtain a phosgene tail gas solution; the phosgene tail gas solution is used as a phosgene raw material for synthesizing pesticide intermediate or acyl chloride chemical products in the action of a composite catalyst; and the composite catalyst contains at least one pyridine or bipyridyl and Lewis acid salt of at least one rare-earth metal. Compared with other methods, the solvent cooling direct absorption method has the advantages of less ...

Medicament composition for preventing and treating thrombosis

The invention relates to pharmaceutical composition used for preventing and treating the disease of thrombosis and a preparation method thereof, and the usage of the composition in treatment of thrombosis associated disease. The composition comprises the components of arecoline, ligustrazine and paeonol.

Method for prepn. of 1 alpha, 25-dihydroxy vitamin Da medicine and anologue

A process for preparing medicine 1 alpha, 25-dihydroxyl VD3 and 1 alpha-hydroxyl VD3 includes introducing branch chain part to 1,3-dihydroxyl steroid, desulfurizing, dehydroxylating to obtain protected precursors of 1 alpha, 25-dihydroxyl VD3 and 1 alpha-hydroxyl VD3, hydrolysis and photochemical treatment. Its advantages are preparing two medicines at same time, gentle reaction condition, shorter process and easy synthesis.

New application of choline compound medicament combination

The invention relates to new application of choline compound medicament combination, in particular to application of combination of a compound shown as a formula (I) and a nonsteroidal antipyretic analgesic to preparation of medicaments for treating and/or preventing pain, particularly central pain or peripheral pain. In the formula, R1 is selected from a hydroxyl group, an acid group of pharmaceutically acceptable inorganic acid or an acid group of pharmaceutically acceptable organic acid; and R2 is selected from hydrogen, an acyl group with one carbon atom to six carbon atoms and a sulphonyl group. The invention also provides a medicinal composition and a medicament box product on the basis of the new application. According to the invention, the compound shown as the formula (I) effectively reduces the effective analgesic dose of the nonsteroidal antipyretic analgesic, shortens the latent period of the nonsteroidal antipyretic analgesic and prolongs analgesic duration of the nonsteroidal ...

Method for preparing 3-(3,4-dichlorophenyl)-1-methoxy-1-methyl urea

The invention discloses a method for preparing 3-(3,4-dichlorophenyl)-1-methoxy-1-methyl urea, which comprises the following steps: taking carbonyl chloride as an acylating agent to carry out an acylation reaction with 3,4-dichlorophenyl; obtaining 3,4-dichlorophenyl isocyanate; generating 1-hydroxy-3-(3,4-dichlorophenyl) urea by the reaction of 3,4-dichlorophenyl isocyanate and hydroxylamine sulfate or hydroxylamine hydrochloride under an alkaline condition; neutralizing 1-hydroxy-3-(3,4-dichlorophenyl) urea and alkali; and obtaining 3-(3,4-dichlorophenyl)-1-methoxy-1-methyl urea by a methylation reaction of 1-hydroxy-3-(3,4-dichlorophenyl) urea and dimethyl carbonate under the condition with a catalyst and a solution. The invention has less quantity of three wastes, high yield, good quality and complete reaction, and can reduce pollution and the cost.

Method for arrangement of leaky coaxial cables applied to strip-shaped elongated area

A method for arrangement of leaky coaxial cables applied to a strip-shaped elongated area, includes: reducing a quantitative radiation performance of initial ends of the leaky coaxial cable combination structures of two areas symmetrically arranged with respect to a central area in a length direction of the strip-shaped elongated area to ensure a small transmission loss, on the premise of ensuring that a comprehensive loss of a link tail end of the leaky coaxial cable is constant; and reducing an appropriate transmission loss of tail ends of the leaky coaxial cable combination structures of the two areas at the central area to increase the radiation performance.

Verfahren zur Anordnung von an einem streifenförmigen länglichen Bereich angebrachten Koaxialleckkabeln

Die Offenbarung stellt ein Verfahren zur Anordnung von Koaxialleckkabeln bereit, die an einem streifenförmigen länglichen Bereich angebracht sind, wodurch eine Verschwendung der Feldstärke an einem anfänglichen Ende eines Koaxialleckkabels vermieden werden kann, ein Signal-Rausch-Verhältnis eines Endsignal-Versorgungsbereichs verbessert werden kann, ein Signalschaltbereich verkürzt werden kann, das Schaltergebnis stabilisiert werden kann und das Ziel eines gleichmäßigen Schaltens erreicht werden kann. Das Verfahren beinhaltet: für Koaxialleckkabel-Kombinationsstrukturen aus zwei Bereichen, die symmetrisch in Bezug auf einen zentralen Bereich in einer Längsrichtung des streifenförmigen länglichen Bereichs angeordnet sind, unter der Prämisse zu gewährleisten, dass ein globaler Verlust eines hinteren Verbindungsendes des Koaxialleckkabels konstant ist, Verringern einer quantitativen Strahlungsleistung der anfänglichen Enden der Koaxialleckkabel-Kombinationsstrukturen der zwei Bereiche relativ weit vom zentralen Bereich entfernt, um einen geringen Übertragungsverlust sicherzustellen; und Verringern eines entsprechenden Übertragungsverlusts der hinteren Enden der Koaxialleckkabel-Kombinationsstrukturen der beiden Bereiche im zentralen Bereich, um die Strahlungsleistung zu erhöhen.