Nano micelle capable of loading antitumor drug as well as preparation method and application of nana micelle

The invention relates to a nano micelle capable of loading an antitumor drug and a preparation method and an application of the nano micelle. The nano micelle is prepared from two biocompatible polyethylene glycol-diethylenetriamine-vitamin E and polyethylene glycol-diethylenetriamine-sulfenyl caprylic acid-vitamin E polymers, wherein the nano micelle is extremely stable in a body and is capable of loading antitumor biological and chemical drugs at a large dose; the loaded biological drug and hydrophobic chemical drug can be one or more drugs; anti-cancer micro ribonucleic acid and chemical antitumor drugs can be effectively and simultaneously conveyed and released to tumor tissues and cancer cells in a controllable manner; the antitumor curative effect is significantly increased; the drug resistance of cancer cells is inhibited; and the polymer for forming the nano micelle is nontoxic, and can be discharged out of a body in a normal metabolic pathway.

Polyethylene glycol-sulfenyl octanoic acid-vitamin E copolymer as well as preparation method and application thereof

The invention discloses a polyethylene glycol-sulfenyl octanoic acid-vitamin E copolymer, namely PEGx-TAy-VEz copolymer as well as a preparation method and application thereof, wherein x, y and z are respectively numbers of repetitive units of PEG, TA and VE, x is 20-1000, y is 2, 4, 6, 8 or 10, and z is 1, 2, 4 or 8; the copolymer is prepared by carrying out peptide condensation reactions on polyethylene glycol, vitamin E and sulfenyl octanoic acid; the copolymer can be used for preparing covalent linked nano-micelle. The preparation method of the PEGx-TAy-VEz copolymer disclosed by the invention is simple, moderate in condition and easy to control; a very stable and long-time recirculation covalent linked nano-micelle for loading anti-tumor drugs can be obtained from the copolymer by a disulfide bond covalent linking technology, and the drugs can be decomposed and released in tumors. The covalent linked nano-micelle can load anti-tumor drugs with large dosage, so that the use of toxic ...

Method for preparing formic acid and acetic acid from carbon dioxide by using hydrothermal technology

The invention discloses a method for preparing formic acid and acetic acid from carbon dioxide by using hydrothermal technology, which belongs to the technical field of hydrothermal chemistry. The method comprises the following steps: performing complex hydrothermal reaction on the carbon dioxide and the water on the surface of nano iron powder, stirring the carbon dioxide and the water at the temperature of between 80 and 240 DEG C under the reaction pressure of 0.1 to 1.6MPa to react for 5 to 120 hours to synthesize the formic acid and the acetic acid. The method provides a new mild reaction route for inactive CO2 molecules. The CO2 is effectively recycled so that the CO2 on the globe can be positively recycled; and the method can prepare the industrial raw materials and reduce the influence of greenhouse effect, and has double meanings of solving resource utilization and environmental protection problems.

Method for preparing organic small-molecule mixture by formaldehyde by using hydrothermal technology

The present invention uses the water heating technology and the formaldehyde to prepare the organic small-molecule mixture, belonging to the field of the water heating chemical technology. The formaldehyde solution and distilled water are used as raw materials; the iron powder or cobalt powder or nickel powder is used as the catalyst; the formaldehyde solution and the catalyst are put into the reactor; the distilled water is added; and the reactor is sealed after stirring evenly; the reaction is done for 1 to 9 days at the temperature between 80 and 160 DEG C; the mixture solution of the formic acid, acetic acid, propionic acid, propionic acid propyl, isopropyl acid and methyl acetate can be got after cooling and filtering. The present invention has the good selectivity, and the environmentally friendly catalyst; the formaldehyde can be reclaimed and effectively reused, and can be transformed to be the useful industrial product. The present invention can not only effectively treat the environmental ...

Domestic wind energy and optical energy power supply system

The invention belongs to the field of domestic power generation devices, and particularly relates to a domestic wind energy and optical energy power supply system. The domestic wind energy and optical energy power supply system comprises a wind energy generator unit and a solar cell panel which are connected in a power generation circuit in parallel, a wire is led out of the solar cell panel and electrically connected with electricity storing equipment through an optical energy controller, a wire is led out of the wind energy generator unit and electrically connected with the electricity storing equipment through a wind energy controller, the electricity storing equipment is electrically connected with direct loads and an inverter through wires, and the inverter is electrically connected with alternating current load electric equipment. Wind energy and solar energy are used sufficiently, and the electricity storing equipment is electrically connected with the direct loads and the inverter ...

Rare earth garnet type ferrite compound and preparation method thereof

The invention discloses a rare earth garnet type ferrite compound and a preparation method thereof, which belong to the technical field of inorganic materials and preparation processes thereof. The rare earth garnet type ferrite compound comprises R3Fe[5-y]MyO12, wherein R is Pr, Nd, Sm or Eu, M is Mn, Cr or V and y is more than or equal to 0 and less than3; and calcium or strontium can be doped at C bit. In the preparation method, trivalent rare earth nitrate and Fe(NO3)3 used as reactants, MnCl2 and the like as doped metal salts and KOH as a mineralizing agent are mixed, stirred and are subjected to alkalinity adjustment and hydrothermal reaction in the presence of a large amount of mineralizing agents. The invention discloses a preparation method of the rare earth garnet type ferrite compound which is difficult to synthesize and is unstable at high temperature and has the characteristics of simple operation, mild conditions, high reaction speed, good repeatability, low cost and the like ...

Method for preparing phenol with carbon-dioxide by using hydrothermal technology

The present invention discloses a method for preparing phenol from carbon dioxide by using hydrothermal technology, which belongs to the hydrothermal chemical technical field. The complex hydrothermal reaction is taken on the surface of metal iron powder by using carbon dioxide and water, and then the phenol is synthesized after agitation and reaction for 5-24h under the reaction pressure of 1.2-1.6Mpa and at the reaction temperature of 160-300 DEG C. The present invention provides a soft reaction route for an inertial CO2 molecule and makes an effective recycle and use for CO2 so that the much better circulation for CO2 on earth can be realized, which can not only prepare an industrial material, but also can decrease the influence of greenhouse effect and have the double significance to solve the resource utilization and environment protection.

Method for preparing phenol with carbon-dioxide by using hydrothermal technology

The present invention discloses a preparation method for phenol from carbon dioxide by using of a heat technology, which belongs to the hydrothermal chemical technology field. The present invention uses the complexed hydrothermal reaction taken on the surface of metal iron powder by carbon dioxide and water, and then to synthesize the phenol by the milling reaction for 5-24 hours under the conditions that the reaction pressure is 1.2-1.6Mpa, the reaction temperature is 160-300 DEG C. The present invention provides a soft reaction route for an inertical CO₂ molecule and makes an effective recycle and use for CO₂; the present invention can realize the much better circulation for CO₂ on earth that can not only prepare an industrial material, but also can decrease the influence of greenhouse effect; the present invention has the double-importance to solve the resource utilization and environment protection.

Method for preparing reaction time controlled chirality amino acid dipeptide

The present invention relates to a preparation method of chirality amino acid dipeptide, the reaction time of which can be controlled. The method belongs to the hydrothermal chemical technology. The alanine is dissolved in distilled water and then is put in high-pressure reaction kettle. Muriatic acid is added into the solution to adjust the Ph value. And then distilled water is added to make the filling volume to be 60 percent to 95 percent of the volume of the reaction kettle. The solution is mixed evenly and is sealed for reaction under the temperature of 80 DEG C to 160 DEG C for a period of time from 0.1 hour to 30 days; then a mixed solution of DD- amino acid dipeptide, LL-amino acid dipeptide and LD- amino acid dipeptide is achieved through cooling and filtering. The proportion of DD- amino acid dipeptide, LL-amino acid dipeptide and LD- amino acid dipeptide can be controlled through the control over the reaction time. The present invention is an effective method for the preparation ...

Active alignment device

The invention provides an active alignment device which is used for automatic recovery of waste material trays and comprises a base, a first platform, a first moving mechanism, a second platform, a pushing mechanism and a second moving mechanism. The first platform is installed on the base. The first moving mechanism is arranged on the base in a sliding mode. And the second platform is mounted on the base. The pushing mechanism is arranged on the base, the pushing mechanism is used for conveying the waste material trays on the first platform to the second platform, and the pushing mechanism is further used for conveying the waste material trays loaded with waste materials on the second platform back to the first platform. The second moving mechanism is arranged on the base in a sliding mode. According to the waste material recycling device, automatic recycling of the waste material disc is achieved, manual operation is reduced, and the production efficiency and safety are improved.

Potassium ferrite and preparation method thereof

The invention discloses potassium ferrite and a preparation method thereof and belongs to the technical field of inorganic materials. The potassium ferrite K2Fe4O7 has a three-dimensional network structure and is lamellar hexagonal; the particle diameter is 260-1000 microns. The preparation method of the potassium ferrite comprises the following steps: adding ferric nitrate nonahydrate into deionized water, dissolving the ferric nitrate nonahydrate, then adding potassium hydroxide and stirring; putting the ferric nitrate nonahydrate in a reactor, sealing and then reacting for 36-48 hours at 240 DEG C; and naturally cooling and filtering to obtain a crude product, washing the crude product with distilled water under ultrasonic vibration till washing liquid is neutral, and drying the crude product to obtain potassium ferrite. The K2Fe4O7 compound is excellent in crystallization degree, high in purity and free of impurity phase; the structure can remain unchanged when the temperature is lower ...

Concrete mixer truck with electric driving force coupling system

The invention discloses a concrete mixer truck with an electric driving force coupling system, which comprises a truck body, a dynamic coupling transmission system, an ISG (Integrated Starter Generator) motor and a power battery, and the truck body comprises a chassis, and a power source, a mixing drum and a hydraulic system which are respectively connected with the chassis. The power coupling transmission system comprises a main input end, an auxiliary input end and an output end, the main input end is connected to a power source through a first cross-shaped transmission shaft, the auxiliary input end is connected to the ISG motor, the output end is connected to a hydraulic system of the mixer truck through a second cross-shaped transmission shaft, and the power battery is electrically connected with the ISG motor. The power source is an engine, the engine is integrated with a power takeoff, the mixing drum is obliquely mounted above the chassis through a front rack and a rear rack, the ...

Triple valence state perovskite type manganese oxide thin film material, preparation and application thereof

Catalyst for clean catalytic oxidation of arene and its preparation

Commercial vehicle coordination type braking system and control method

The invention relates to a commercial vehicle coordinated braking system and a control method. The commercial vehicle coordinated braking system comprises a control unit which is connected with a main braking system and an auxiliary braking system; specific auxiliary braking is provided according to the type of the vehicle, and the braking force can be controlled by a corresponding electric control unit; in the braking process of the vehicle, the whole vehicle control unit detects the braking requirement of a driver, and meanwhile, in combination with the working state of the auxiliary braking system, the braking force of the vehicle in the early braking stage is controlled to be all provided by the auxiliary braking system. When the braking force of the auxiliary braking system cannot meet the braking requirement, the whole vehicle control unit adjusts the proportional electromagnetic valve of the main braking gas circuit and controls the main braking system to conduct braking force compensation ...

Catalyst for clean catalytic oxidation of arene and its preparation

The catalyst is dark green crystal with molecular formula of Cu2(OH)x(PO4)y and molecular weight of 345.7. It is synthesized through hydrothermal crystallization process, during which the initial reaction mixture obtained by mixing copper acetate, phosphoric acid, ethylenediamine and water in certain molar proprotion is crystallized in reactor at 100-220 deg.c for 1-10 days and after suction filtration and drying, the product is obtained. The said catalyst has high catalytic activity and homogeneous granularity, and is stable and easy to regenerate.

Preparation method of perovskite type silver niobium tantalate solid solution

The invention provides a preparation method of a perovskite type silver niobium tantalate solid solution, and belongs to the technical field of inorganic material preparation. A perovskite type silver niobium tantalite compound AgNb1-xTaxO3 (0 Подробнее

Solar street lamp having charging function

The invention discloses a solar street lamp having a charging function. The solar street lamp comprises a lamp post, a lamp holder, a control box, a charging interface and a solar panel, wherein the lamp holder is arranged at the top end of the lamp post fixed on the ground, a lamp bulb is installed in the lamp holder, and the solar panel is installed on the top face of a casing of the lamp holder and electrically connected with an inverter installed in the control box on the lamp post through a lead wire passing through the inside of the lamp post. The inverter is electrically connected with an energy storage device in the control box through a lead wire and electrically connected with the lamp bulb through a lead wire, a groove is formed in the lamp post, the charging interface is arranged in the groove and electrically connected with the inverter through a lead wire passing through the inside of the lamp post. People can conveniently charge mobile phones when the mobile phones are out ...

Method for preparing amino acid by aliphatic acid by using hydrothermal technology

The present invention provides a method of using the water heating technology to prepare the amino acid with the fatty acid, belonging to the technological field of the water heating chemistry. The ferric oxide, the zirconium oxychloride, the samarium oxide or the titanium dioxide is used as the catalyst; the acetic acid or propionic acid and the ammonia water are used to do the water heating reaction to get the glycin or alanine. The products are all tested and identified through the highly efficient liquid phase chromatography (using LC). The present invention provides a novel synthetic route for the synthesis of the amino acid, and is the original invention; the invention is characterized in the mild synthetic conditions, the one-step synthesis, and the easy operation and so on.

Support is pour to bridge that recycles

The utility model discloses a support is pour to bridge that recycles, including supporting the steelframe, support one side fixedly connected with fixing device at steelframe top to one side swing joint who supports the steelframe surface has rotating device, fixing device includes the casing to the bottom of casing and one side fixed connection who supports the steelframe top, one side fixedly connected with fixed plate of casing inner wall to the bottom fixedly connected with slider of fixed plate, the positive sliding connection of slider has the latch, the utility model relates to a support technical field pours. This support is pour to bridge that recycles having changed and having carried out demolising of support when the construction is accomplished, trouble that the process of demolising is suitable to cause the damage to the steel pipe, problem that can not the reutilization makes the support obtain cyclic utilization, and significantly reduced workman's intensity of labourand ...