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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 16. Отображено 16.
03-03-2010 дата публикации

Safety infusion device

Номер: CN0101658699A
Автор: GUO ZHAOPEI, GUO ZHIKAI, GUO ZHITAO, ZHAOPEI GUO, ZHIKAI GUO, ZHITAO GUO
Принадлежит:

The invention discloses a safety infusion device, which comprises a plastic syringe needle, an infusion tube, a Murphy's drop apparatus, a slide switch, a filter, a syringe needle, and a syringe needle handle, wherein the rear of the syringe needle is provided with an outer sleeve, while the front is provided with a syringe needle sleeve; the rear of the syringe needle sleeve is arranged between the outer sleeve and the syringe needle in a sliding way; the front end of the syringe needle sleeve has a tapered opening structure; one side of the rear of the syringe needle sleeve is provided witha push handle; a push handle sliding groove is axially arranged on the sleeve corresponding to the push handle of the syringe needle sleeve; the rear end of the sliding groove is provided with a pushhandle notch along the circumferential direction of the outer sleeve; and the outer sleeve corresponding to the syringe needle handle is provided with a fixing handle, and a fixing tape matched with the ...

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Номер записи: 1
01-10-2008 дата публикации

Apparatus and method of polymer photoresist ultrasonic ageing effect

Номер: CN0101276159A
Автор: DU LIQUN, YU LICHUAN, WANG YU, GUO ZHAOPEI, LIQUN DU, LICHUAN YU, YU WANG, ZHAOPEI GUO
Принадлежит:

The present invention provides a device and method of polymer photoresist ultrasound aging, belonging to ultrasonic application field, characterized in that the polymer photoresist ultrasound aging device includes an ultrasonic generator, an ultrasonic transducer, a worktable and a casing, the characteristics is that the worktable is connected with the ultrasonic transducer, the casing supports the worktable which is suspended with the transducer. The method of the polymer photoresist ultrasound aging is characterized in that the silicon is cleaned in the standard process, coated with the photoresist after dried, exposing under the uv, ensuring SU-8 adhesive crosslink after dried; the adhesive layer is processed with an ultrasound aging: the ultrasonic generator transmits a high frequency electrical signal to drive the ultrasonic transducer vibrate and transmitting to the worktable. The invention has effects and advantages of effectively reducing the internal stress of the polymer photoresist ...

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Номер записи: 2
27-06-2012 дата публикации

Cross linking polymer and preparation method thereof

Номер: CN0101880397B
Автор: CHEN XUESI, XIA JIALIANG, TIAN HUAYU, CHEN LEI, LI FEIFAN, CHEN JIE, GUO ZHAOPEI, LIN LIN, XUESI CHEN, JIALIANG XIA, HUAYU TIAN, LEI CHEN, FEIFAN LI, JIE CHEN, ZHAOPEI GUO
Принадлежит:

The invention provides a cross linking polymer. Molecules of the cross linking polymer at least comprise a first repeated unit in a structure as a formula (I) and a second repeated unit in a structure as a formula (II), wherein n is greater than 1 and less than 25, Q is alkyl or aryl, R1 is polymine with the molecular weight between 100 and 2000, and the molecular weight of the cross linking polymer is between 5000 and 100000. The invention also provides a preparation method of the cross linking polymer. Compared with the prior art, the cross linking polymer provided by the invention has larger molecular weight because of the two repeated units in the cross linking polymer provided by the invention, so the gene transfer efficiency of the cross linking polymer can be improved. At the same time, both the two repeated units have low cell toxicity. Thereby, the toxicity of the cross linking polymer is low. Experiments show that when the cross linking polymer provided by the invention is used ...

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Номер записи: 3
25-01-2012 дата публикации

Gene vector system containing targeted shading system, preparation and use thereof

Номер: CN0101302532B
Автор: CHEN XUESI, LIN LIN, GUO ZHAOPEI, XIA JIALIANG, TIAN HUAYU, CHEN LEI, JING XIABIN, XUESI CHEN, ZHAOPEI GUO, JIALIANG XIA, HUAYU TIAN, LEI CHEN, XIABIN JING
Принадлежит:

The invention relates to a gene delivery system containing a target shielding system and a preparation method and application thereof. The gene delivery system consists of a shielding system with a target ligand, a cation polymer material and plasmid DNA, wherein, the cation polymer material and the plasmid DNA are compounded to form compound particles, and the shielding system with the target ligand is shielded on the surface of the compound through electrostatic effect. The gene delivery system containing the target shielding system can transfer a loaded genic material into cells to realizethe expression of the genic material and finish a transfection process, and the targeting of gene transfection can be improved. The preparation method has the advantages that: the target ligand is grafted onto the shielding system; on the one hand, the targeting strategy can not affect the compound ability of a cationic polymer to the DNA, on the other hand, the targeting strategy can also guarantee ...

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Номер записи: 4
03-02-2010 дата публикации

Application of amphipathy macromolecule cation polymer

Номер: CN0101638668A
Автор: HUAYU TIAN, XUESI CHEN, JIE CHEN, ZHAOPEI GUO, LIN LIN, LEI CHEN, JIALIANG XIA, XIABIN JING, TIAN HUAYU, CHEN XUESI, CHEN JIE, GUO ZHAOPEI, CHEN LEI, XIA JIALIANG, JING XIABIN
Принадлежит:

The invention relates to application of amphipathy macromolecule cation polymer, wherein the polymer is taken as a siRNA transfection carrier. The polymer is a non virus gene carrier. The gene silentefficiency is high, and cell toxicity is less. The highest gene silent efficiency of CT26 cell for constantly expressing luciferase is 73.4%; and in 6h liquid change experiment after transfection, thehighest gene silent efficiency of 4T1 cell for constantly expressing luciferase is 63.7%. In the Hella cell experiment of transient transfection, compared with commercial PEI-25K and liposome 2000, the amphipathy macromolecule cation polymer has higher gene silent efficiency and less cell toxicity. In the 6h liquid change experiment after transfection, the reduction of the cell toxicity of the amphipathy macromolecule cation polymer is less.

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Номер записи: 5
03-03-2010 дата публикации

Coating machine for wall coatings

Номер: CN0101658831A
Автор: GUO ZHAOPEI, GUO ZHIKAI, GUO ZHITAO, ZHAOPEI GUO, ZHIKAI GUO, ZHITAO GUO
Принадлежит:

The invention relates to a coating device for large-area wall advertisements, propagandas and under colors of posters, and discloses a coating machine for wall coatings, which comprises a main board;the inner lateral surface of the main board is fixed with a tubular main nozzle piece; the front of the main nozzle piece is provided with a nozzle; the rear of the main nozzle piece is provided witha feed pipe passing through the main board; two ends of the main nozzle piece are enclosed by end caps; and outer end faces of the end caps are provided with liquid baffle plates. The coating machineis provided with the liquid baffle plates to ensure neat edges of the coating, can be provided with a plurality of additional nozzle pieces to achieve wide spraying amplitude, and is provided with rollers to ensure labor-saving spraying and quick spraying. The coating machine is suitable for coating various coatings, and has wide application, simple structure, light weight because parts are made of light ...

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Номер записи: 6
20-04-2011 дата публикации

Application of hyperbranched polymine-spherical gold nanoparticles

Номер: CN0102021225A
Автор: Tian Huayu, Chen Xuesi, Guo Zhaopei, Li Yanhui, Chen Jie, Lin Lin, Jing Xiabin
Принадлежит:

The invention provides application of hyperbranched polymine-spherical gold nanoparticles to fluorescence labeling. The nanoparticles consist of gold nanoparticles and hyperbranched polymine which are combined with each other through a sulfur gold bond, wherein the molecular weight of the polymine is between 300 and 30,000; and the mass ratio of the gold nanoparticles to cationic polymer is 1:100-100:1. When the spherical gold nanoparticles are applied to fluorescence labeling, the effective ranges of excitation wavelength and emission wavelength are wide; when the excitation wavelength is between 400 and 450 nanometers and ultraviolet light with the optimum excitation wavelength of 430 nanometers is excited, red light with the emission wavelength peak value of between 720 and 800 nanometers is emitted; and when ultraviolet light with the excitation wavelength of 370 nanometers is excited, yellow light with the emission wavelength peak value of about 600 nanometers is emitted. The defect ...

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Номер записи: 7
12-01-2011 дата публикации

Application of amphipathy macromolecule cation polymer

Номер: CN0101638668B
Автор: HUAYU TIAN, XUESI CHEN, JIE CHEN, ZHAOPEI GUO, LIN LIN, LEI CHEN, JIALIANG XIA, XIABIN JING, TIAN HUAYU, CHEN XUESI, CHEN JIE, GUO ZHAOPEI, CHEN LEI, XIA JIALIANG, JING XIABIN
Принадлежит:

The invention relates to application of amphipathy macromolecule cation polymer, wherein the polymer is taken as a siRNA transfection carrier. The polymer is a non virus gene carrier. The gene silent efficiency is high, and cell toxicity is less. The highest gene silent efficiency of CT26 cell for constantly expressing luciferase is 73.4%; and in 6h liquid change experiment after transfection, the highest gene silent efficiency of 4T1 cell for constantly expressing luciferase is 63.7%. In the Hella cell experiment of transient transfection, compared with commercial PEI-25K and liposome 2000, the amphipathy macromolecule cation polymer has higher gene silent efficiency and less cell toxicity. In the 6h liquid change experiment after transfection, the reduction of the cell toxicity of the amphipathy macromolecule cation polymer is less.

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Номер записи: 8
12-11-2008 дата публикации

Gene vector system containing targeted shading system, preparation and use thereof

Номер: CN0101302532A
Автор: TIAN HUAYU, CHEN XUESI, LIN LIN, XIA JIALIANG, CHEN LEI, GUO ZHAOPEI, JING XIABIN, HUAYU TIAN, XUESI CHEN, JIALIANG XIA, LEI CHEN, ZHAOPEI GUO, XIABIN JING
Принадлежит:

The invention relates to a gene delivery system containing a target shielding system and a preparation method and application thereof. The gene delivery system consists of a shielding system with a target ligand, a cation polymer material and plasmid DNA, wherein, the cation polymer material and the plasmid DNA are compounded to form compound particles, and the shielding system with the target ligand is shielded on the surface of the compound through electrostatic effect. The gene delivery system containing the target shielding system can transfer a loaded genic material into cells to realize the expression of the genic material and finish a transfection process, and the targeting of gene transfection can be improved. The preparation method has the advantages that: the target ligand is grafted onto the shielding system; on the one hand, the targeting strategy can not affect the compound ability of a cationic polymer to the DNA, on the other hand, the targeting strategy can also guarantee ...

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Номер записи: 9
03-02-2010 дата публикации

Polyethylene glycol monomethyl ether-poly 2-methyl-carboxyl propylene carbonate graft polyethyleneimine copolymer, preparation method thereof and application thereof

Номер: CN0101638484A
Автор: CHEN XUESI, CHEN LEI, TIAN HUAYU, GUO ZHAOPEI, CHEN JIE, LIN LIN, HUANG YUBIN, JING XIABIN, XUESI CHEN, LEI CHEN, HUAYU TIAN, ZHAOPEI GUO, JIE CHEN, YUBIN HUANG, XIABIN JING
Принадлежит:

The invention relates to polyethylene glycol monomethyl ether-poly 2-methyl-carboxyl propylene carbonate graft polyethyleneimine copolymer, a preparation method thereof and application thereof. The preparation method comprises the step of directly condensing carboxyl in the polyethylene glycol monomethyl ether-poly 2-methyl-carboxyl propylene carbonate graft polyethyleneimine segmented copolymer with amino in polyethyleneimine to form the graft copolymer. The copolymer is a polycation gene carrier, integrates the advantages of polyethylene glycol, Makrolan and polyethyleneimine, and has high transfection efficiency, wherein the highest transfection efficiency to the medium luciferase plasmid of african green monkey kidney cell is 14 times of that of American Invitrogen biological company transfection reagent Lipofetamine2000, can effectively antagonize the inhibiting effect of blood serum to the transfection, and has less cell toxicity, wherein consistency thereof is not higher than ...

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Номер записи: 10
08-04-2009 дата публикации

Nano-golden particle-containing non-virogene carrier, production method and uses thereof

Номер: CN0101402965A
Автор: TIAN HUAYU, CHEN XUESI, GUO ZHAOPEI, LI YANHUI, CHEN JIE, LIN LIN, JING XIABIN, HUAYU TIAN, XUESI CHEN, ZHAOPEI GUO, YANHUI LI, JIE CHEN, XIABIN JING
Принадлежит:

The invention belongs to the biotechnology field and relates to a non-viral gene vector containing nano-gold particles, a preparation method and an application. The gene vector is composed of nano-gold particles and a polymer containing polyethylenimine by binding by sulfur-gold bonds; and complex particles are compounded by the gene vector containing the nano-gold particles and DNA of genetic materials. The complex particles can transfer the genetic materials into cells to realize the expression of the genetic materials and complete the transfection process. The highest transfection efficiency of the non-viral gene vector containing the nano-gold particles to HeLa cells is 3.1 times of the commercial PEI transfection efficiency, the highest transfection efficiency to CHO cells is 4.5 times of the commercial PEI transfection efficiency, and the highest transfection efficiency to COS cells is 3.6 times of the commercial PEI transfection efficiency. The cell viability is higher than 87 percent ...

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Номер записи: 11
09-06-2010 дата публикации

Garden whitewashing machine

Номер: CN0101722130A
Автор: GUO ZHAOPEI, GUO ZHIKAI, GUO ZHITAO, ZHAOPEI GUO, ZHIKAI GUO, ZHITAO GUO
Принадлежит:

The invention discloses a garden whitewashing machine, comprising a coating device, a regulating device and an annular mounting bracket; wherein the coating device is arranged on the regulating device, the regulating device is arranged on the annular mounting bracket, the annular mounting bracket is composed of two semi-circle annular mounting brackets, and corresponding ends of the two semi-circle annular mounting brackets are hinged. The invention has simple operation, convenient use, uniform coating, high efficiency and low labour intensity, saves soup and has less influence on health of operator, thus being applicable to trees in different tree diameters and different soup spraying heights; the invention is easy to dismount and mount, also can be applied to coating on the surface of telegraph pole and other columnar objects, has good market prospect and is easy to popularize and use.

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Номер записи: 12
11-05-2011 дата публикации

Apparatus and method of polymer photoresist ultrasonic ageing effect

Номер: CN0101276159B
Автор: GUO ZHAOPEI, YU LICHUAN, DU LIQUN, WANG YU, ZHAOPEI GUO, LICHUAN YU, LIQUN DU, YU WANG
Принадлежит:

The present invention provides a device and method of polymer photoresist ultrasound aging, belonging to ultrasonic application field, characterized in that the polymer photoresist ultrasound aging device includes an ultrasonic generator, an ultrasonic transducer, a worktable and a casing, the characteristics is that the worktable is connected with the ultrasonic transducer, the casing supports the worktable which is suspended with the transducer. The method of the polymer photoresist ultrasound aging is characterized in that the silicon is cleaned in the standard process, coated with the photoresist after dried, exposing under the uv, ensuring SU-8 adhesive crosslink after dried; the adhesive layer is processed with an ultrasound aging: the ultrasonic generator transmits a high frequencyelectrical signal to drive the ultrasonic transducer vibrate and transmitting to the worktable. The invention has effects and advantages of effectively reducing the internal stress of the polymer photoresist ...

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Номер записи: 13
10-11-2010 дата публикации

Cross linking polymer and preparation method thereof

Номер: CN0101880397A
Автор: XUESI CHEN, JIALIANG XIA, HUAYU TIAN, LEI CHEN, FEIFAN LI, JIE CHEN, ZHAOPEI GUO, LIN LIN, CHEN XUESI, XIA JIALIANG, TIAN HUAYU, CHEN LEI, LI FEIFAN, CHEN JIE, GUO ZHAOPEI
Принадлежит:

The invention provides a cross linking polymer. Molecules of the cross linking polymer at least comprise a first repeated unit in a structure as a formula (I) and a second repeated unit in a structure as a formula (II), wherein n is greater than 1 and less than 25, Q is alkyl or aryl, R1 is polymine with the molecular weight between 100 and 2000, and the molecular weight of the cross linking polymer is between 5000 and 100000. The invention also provides a preparation method of the cross linking polymer. Compared with the prior art, the cross linking polymer provided by the invention has larger molecular weight because of the two repeated units in the cross linking polymer provided by the invention, so the gene transfer efficiency of the cross linking polymer can be improved. At the same time, both the two repeated units have low cell toxicity. Thereby, the toxicity of the cross linking polymer is low. Experiments show that when the cross linking polymer provided by the invention is used ...

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Номер записи: 14
16-02-2011 дата публикации

Modified polyethyleneimine and preparation method thereof

Номер: CN0101974154A
Автор: XUESI CHEN, JIALIANG XIA, HUAYU TIAN, LEI CHEN, FEIFAN LI, JIE CHEN, ZHAOPEI GUO, LIN LIN, CHEN XUESI, XIA JIALIANG, TIAN HUAYU, CHEN LEI, LI FEIFAN, CHEN JIE, GUO ZHAOPEI
Принадлежит:

The invention provides modified polyethyleneimine expressed as a formula I. In the formula, R is H or a substituent group expressed as a formula II; m is an integer of 1 to 700, n is an integer of 1 to 700, and the sum of the n and the m is an integer of 200 to 700; and the number of the substituent group expressed in the formula II is 10 to 120. The L-phenylalanine modified polyethyleneimine provided by the invention has double sensitivities to temperature and pH. In addition, L-phenylalanine is one of amino acids necessary to the human body and has hydrophobic property and biocompatibility, so the L-phenylalanine grafted on the polyethyleneimine can provide the hydrophobic property for the polyethyleneimine, the modified polyethyleneimine has amphipathy and good biocompatibility, and the cell toxicity of a modified polyethyleneimine material is reduced. The invention also provides a preparation method for the modified polyethyleneimine.

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Номер записи: 15
25-07-2012 дата публикации

Modified polyethyleneimine and preparation method thereof

Номер: CN0101974154B
Автор: XUESI CHEN, JIALIANG XIA, HUAYU TIAN, LEI CHEN, FEIFAN LI, JIE CHEN, ZHAOPEI GUO, LIN LIN, CHEN XUESI, XIA JIALIANG, TIAN HUAYU, CHEN LEI, LI FEIFAN, CHEN JIE, GUO ZHAOPEI
Принадлежит:

The invention provides modified polyethyleneimine expressed as a formula I. In the formula, R is H or a substituent group expressed as a formula II; m is an integer of 1 to 700, n is an integer of 1 to 700, and the sum of the n and the m is an integer of 200 to 700; and the number of the substituent group expressed in the formula II is 10 to 120. The L-phenylalanine modified polyethyleneimine provided by the invention has double sensitivities to temperature and pH. In addition, L-phenylalanine is one of amino acids necessary to the human body and has hydrophobic property and biocompatibility,so the L-phenylalanine grafted on the polyethyleneimine can provide the hydrophobic property for the polyethyleneimine, the modified polyethyleneimine has amphipathy and good biocompatibility, and the cell toxicity of a modified polyethyleneimine material is reduced. The invention also provides a preparation method for the modified polyethyleneimine.

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Номер записи: 16