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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Применить Всего найдено 3. Отображено 3.
26-10-2005 дата публикации

Cocaine-benzedrine regulating transcription peptide gene vaccine, its preparation and application

Номер: CN0001686564A
Принадлежит:

A genetic vaccine able to resist against the psychogenic dependency to the active psychotropic substance, such as morphin, is prepared through cloning the cocaine-phenylpropanamine regulatory transcription peptide (CART) gene to eukaryotic plasmid expression carrier pcDNA3.1(+), and directly injecting the reecombinant plasmid DNA into the body of animal for expressing the CART and generating antigen to activate the immune system.

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09-11-2011 дата публикации

Cocaine-and amphetamine-regulated transcript peptides single-chain antibody and application thereof

Номер: CN0101280016B
Принадлежит:

Disclosed is a new antibody which can be used to relieve addiction caused by nerve active substances, including opium, cocaine, benzedrine, ketamine, etc. Cocain and amphetamine-regulated transcript peptide antibody gene is selected through phage display technology; then single-chain antibody sequence of the cocain and amphetamine-regulated transcript peptide(CART) and the procaryon expression vector are connected and are induced to express and to be purified to obtain single-chain antibody in response to CART, which is named as CARTscFv(AH1,AH4B,AH6,AH19,AH33B,AH36). Injecteion of CARTscFvinto the abdominal cavity of a mouse, together with the CART at the peripheral circulation system, leads to the reduction of the CART in the central nervous system of the mouse. Animal model with behavioral sensitization induced by cocain proves that the CART single-chain antibody can restrain the expression of the behavioral sensitization of the mouse induced by cacain, which shows that the CART single-chain ...

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08-10-2008 дата публикации

Cocaine-and amphetamine-regulated transcript peptides single-chain antibody and application thereof

Номер: CN0101280016A
Принадлежит:

Disclosed is a new antibody which can be used to relieve addiction caused by nerve active substances, including opium, cocaine, benzedrine, ketamine, etc. Cocain and amphetamine-regulated transcript peptide antibody gene is selected through phage display technology; then single-chain antibody sequence of the cocain and amphetamine-regulated transcript peptide(CART) and the procaryon expression vector are connected and are induced to express and to be purified to obtain single-chain antibody in response to CART, which is named as CARTscFv(AH1,AH4B,AH6,AH19,AH33B,AH36). Injecteion of CARTscFv into the abdominal cavity of a mouse, together with the CART at the peripheral circulation system, leads to the reduction of the CART in the central nervous system of the mouse. Animal model with behavioral sensitization induced by cocain proves that the CART single-chain antibody can restrain the expression of the behavioral sensitization of the mouse induced by cacain, which shows that the CART single-chain ...

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