ДВУХКАМЕРНЫЙ КОНТЕЙНЕР ДЛЯ ДОЗИРУЕМЫХ АЭРОЗОЛЕЙ, НЕ СОДЕРЖАЩИХ ПРОПЕЛЛЕНТА

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СОЕДИНИТЕЛЬНОЕ УСТРОЙСТВО

Группа изобретений относится к области медицины и может быть использована для гидравлического соединения двух уплотненных мембраной емкостей. Соединительное устройство содержит два элемента, которые выполнены с возможностью скользящего смещения относительно друг друга вдоль оси между первым и вторым положением. Первый элемент содержит полую переходную иглу с двумя заостренными концами, расположенную параллельно указанной оси таким образом, что мембрана первой из двух емкостей пронизывается одним концом иглы, когда указанная первая емкость вводится в гнездо первого элемента. При этом второй элемент содержит средство для разъемного сцепления со второй из двух емкостей, причем другой конец иглы не входит в контакт с мембраной второй емкости, соединенной со вторым элементом, когда элементы находятся в первом положении, и другой конец иглы пронизывает мембрану второй емкости, когда элементы находятся во втором положении, устанавливая тем самым гидравлическое соединение между двумя емкостями.

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БЕЗОПАСНОЕ ЗАПОРНОЕ УСТРОЙСТВО С ВЕНТИЛЯЦИЕЙ

Группа изобретений относится к области медицины. Запорное устройство (20) для использования с контейнером-сборником (22) пробы содержит основание (24) с первым концом для введения в открытый конец контейнера-сборника пробы и вторым концом для введения в него части шприца. Запорное устройство содержит также соединитель (38) Люера, присоединенный к основанию по меньшей мере один канал (52) для вентиляции внутреннего пространства контейнера-сборника пробы в процессе передачи пробы текучей среды из шприца в контейнер-сборник пробы, примыкающий к соединителю Люера, и закрывающую часть (28). Закрывающая часть (28) присоединена к основанию (24) и приспособлена для перевода из открытого положения, в котором устанавливается сообщение для текучей среды между первым концом и вторым концом через соединитель Люера, в закрытое положение, в котором соединитель Люера полностью прикрыт закрывающей частью. При этом первый конец основания (24) содержит по меньшей мере одно отклоняемое ребро (40) для формирования ...

ДОЗИРОВАНИЕ ЖИДКОСТЕЙ И СПОСОБЫ ДОЗИРОВАНИЯ ЖИДКОСТЕЙ

Группа изобретений относится к области дозирования жидкостей. Дозатор для подачи отмеренного объема жидкого лекарственного средства в аэрозольное устройство содержит: контейнер для хранения жидкого лекарственного средства, имеющий проксимальный конец и дистальный конец; дозирующий механизм, соединенный с дистальным концом контейнера, содержащий дистальный конец. Дозирующий механизм, предназначенный для дозирования отмеренного объема жидкого лекарственного средства из наконечника, содержит неподвижный участок, соединенный со скользящим участком, при этом в несжатом состоянии скользящий участок находится в смещенном от контейнера положении, скользящий участок выполнен с возможностью его сжатия по направлению к неподвижному участку. Дистальный конец дозирующего механизма включает в себя переходный элемент, который взаимодействует с корпусом аэрозольного устройства. Также раскрывается способ изготовления дозатора, способ подачи жидкого лекарственного средства и вариант дозатора. Группа изобретений ...

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Изобретение относится к области приготовления медицинских составов. Система перемещения содержимого контейнеров содержит первый и второй контейнер, которые могут быть соединены друг с другом с возможностью перемещения среды посредством соединительного устройства, которое содержит устройство перемещения содержимого, которое, будучи удерживаемо при помощи запирающего устройства в заблокированном положении, препятствует обмену сред или делает возможным обмен сред в разблокированном положении. При этом запирающее устройство выполнено с возможностью перевода в разблокированное положение путем перемещения контейнера; на указанном подвижном контейнере предусмотрены дополнительные средства управления, которые по меньшей мере частично охватывают этот контейнер снаружи и воздействуют на запирающее устройство устройства перемещения содержимого с обеспечением его разблокирования. Соединительное устройство в качестве приемной части устройства перемещения содержимого и запирающего устройства содержит ...

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Изобретение относится к медицинской технике, а именно к системам смешивания лекарств. Система смешивания лекарств содержит, по меньшей мере, один элемент сопряжения с гнездом емкости с жидкостью, по меньшей мере, один элемент сопряжения с ампулой с лекарством и, по меньшей мере, один элемент сопряжения со шприцем, выполненный с возможностью прикрепления к шприцу и к, по меньшей мере, одному из следующих компонентов: по меньшей мере, одному элементу сопряжения с гнездом емкости и, по меньшей мере, одному элементу сопряжения с ампулой. По меньшей мере, один из следующих компонентов: по меньшей мере, один элемент сопряжения с гнездом емкости, по меньшей мере, один элемент сопряжения со шприцем и, по меньшей мере, один элемент сопряжения с ампулой снабжен воздуховодом в окружающую среду, выполненным с возможностью предотвращения пропускания в окружающую среду потенциально вредного содержимого ампулы в жидкой, твердой или газообразной форме. Изобретение позволяет работать с токсичными лекарствами ...

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В способе формуют корпус, включающий камеру, в первой пресс-форме в чистой комнате и формуют часть контейнера во второй пресс-форме в чистой комнате того же класса, что и первая, при этом в части контейнера устройством для заполнения контейнера может быть выполнен прокол с образованием отверстия с возможностью восстановления ее герметичности. Затем собирают вместе часть контейнера и корпус в чистой комнате для получения пустой герметично закрытой камеры. Изобретение обеспечивает повышение герметичности, когда в части контейнера выполняют прокол. 14 з.п. ф-лы, 66 ил.

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Изобретение предназначено для смешивания первого компонента, такого, как парентерально вводимая текучая среда 27, с вторым компонентом, таким, как неподвижно удерживаемое спорной структурой 50 лекарственное средство, для образования целебного вещества, непосредственно вливаемого больному. Устройство содержит механизмы для соединения с обеспечением сопряжения стеклянного пузырька 30, который содержит первый компонент, с корпусом 12, имеющим выходное отверстие 22 для текучей среды. В корпусе 12 размещен герметично закрытый контейнер 44, содержащий второй компонент. Последующее регулируемое смешивание компонентов производится в стерильных условиях для образования вводимого внутрь раствора, который автоматически вытесняется через выходное отверстие 22 для выхода текучей среды. Технический результат - обеспечение возможности добавления в стерильной среде к растворителю или другой парентерально вводимой текущей среды, содержащейся внутри стеклянного пузырька, заданных компонентов, химических ...

СПОСОБ ЛИОФИЛИЗАЦИИ И ГЕРМЕТИЗАЦИИ ВПРЫСКИВАЕМОГО ПРОДУКТА И КОНТЕЙНЕР ДЛЯ ЛЕОФИЛИЗАЦИИ И ГЕРМЕТИЗАЦИИ ВПРЫСКИВАЕМОГО ПРОДУКТА

Изобретение относится к герметизации и распределению лиофилизированного лекарства в контейнере. Технический результат заключается в повышении надежности. Технический результат достигается за счет того, что способ осуществляют с применением устройства усовершенствованной конструкции. Лиофилизацию проводят в контейнере, который устанавливают в камере, удаляют кислоту из контейнера и вводят азот, закрывают колпачок путем создания давления, выпускное отверстие блокируют от сообщения с первым отверстием в контейнере. Согласно изобретению вводят наконечник штока плунжера, имеющий головку в гильзе так, что наконечник штока плунжера выступает из второго отверстия в контейнере, причем головка расположена аксиально смежно с плунжером. Устанавливают контейнер в открытый конец гильзы. Контейнер аксиально удерживается в гильзе против выступающего радиально внутрь упора на гильзе и прочно закрепляют гильзу на колпачке. 2 с. и 6 з.п. ф-лы, 14 ил.

НАСОС-ДОЗАТОР

Предложение относится к дозирующим устройствам и может быть использовано преимущественно в медицине или фармацевтической промышленности, например, для дозаторов лекарственных средств в ампульном производстве, а также в любой области техники.Насос-дозатор состоит из корпуса с подающим и нагнетательным каналами, шибера с каналом, плунжера, рабочий конец которого размещен в дозирующей камере, и толкателя плунжера, выполненного с элементом для кинематического соединения с приводом. Толкатель выполнен разъемным, причем одна из его частей выполнена с цилиндрическими выточками, а элемент для кинематического соединения с приводом находится на другой его части. Другой конец плунжера выполнен с уступом и размещен в толкателе с возможностью взаимодействия с его стенками. Технический результат - улучшенная точность и стабильность дозирования, в особенности малых доз при одновременном повышении долговечности устройства. 1 з.п. ф-лы, 5 ил.

УСТРОЙСТВО ДЛЯ ПЕРЕКАЧКИ РАСТВОРА ИЗ ОДНОГО ГЕРМЕТИЗИРОВАННОГО КОНТЕЙНЕРА В ДРУГОЙ

Использование: в устройствах для транспортировки растворов из одного герметичного контейнера в другой. Сущность изобретения: устройство включает цилиндрический корпус, диск и смонтированные в нем иглообразные трубки для транспортирования раствора из одного контейнера в другой и подачи газа в контейнер. Цилиндрический корпус и диск образуют полости для приема контейнера. Трубка может быть укреплена наклонно в теле диска и ее концы расположены с противоположных сторон диска, параллельно его оси. На наружной цилиндрической поверхности диска может быть образовано отверстие, диаметр которого больше диаметра трубки для подачи газа. 2 з.п. ф-лы, 7 ил.

УСТРОЙСТВО ДЛЯ ХРАНЕНИЯ И ТОЧНОГО ДОЗИРОВАНИЯ ЖИДКОСТЕЙ

Устройство предназначено для хранения и дозирования жидкостей, в частности жидких лекарств. Устройство содержит флакон, крышку, неподвижно соединенную с горловиной флакона и с полым цилиндром, расположенным вдоль центральной оси флакона, и дозирующее устройство. Дозирующее устройство включает гильзу и плунжер. Дозирующее устройство обеспечивает единственный способ извлечения лекарственного средства из флакона. Изобретение позволяет обеспечить безопасность и удобство в эксплуатации. 6 з.п.ф-лы., 3 ил.

МНОГОКАМЕРНАЯ ЕМКОСТЬ

Использование: в емкостях с несколькими камерами, используемыми, главным образом, в области медицины. Сущность изобретения: корпус емкости выполнен из эластичного пластика и имеет разделительные средства, делящие корпус на камеры и обеспечивающие связь между камерами в случае необходимости. По крайней мере одна из камер закрывается крышкой с целью образования замкнутого пространства вокруг камеры. Крышка выполнена из эластичной пленки, отличающейся влаго- и газозащитными свойствами. Технический результат заключается в обеспечении раздельного хранения растворителя и растворимого вещества и их смешении непосредственно перед употреблением, а также в повышении экономичности. 10 з.п. ф-лы, 13 ил.

ГЕРМЕТИЧНЫЙ КОНТЕЙНЕР И СПОСОБ ЕГО ИЗГОТОВЛЕНИЯ ИЗАПОЛНЕНИЯ

... 1. Пузырек в сборе для хранения вещества, содержащий корпус, снабженный отверстием, камеру, в которую через отверстие может быть введено вещество, основание, среднюю часть и верхнюю часть, которая отделена в направлении оси от основания средней частью, причем размеры основания и верхней части в горизонтальной плоскости больше, чем максимальный размер средней части в горизонтальной плоскости, и заглушку, которая введена в отверстие и в которой иглой или иным подобным элементом может быть выполнен прокол для осуществления, по крайней мере, одного из следующих действий: введения в камеру вещества или извлечения его из камеры. 2. Пузырек в сборе по п.1, отличающийся тем, что поперечное сечение основания, средней части и верхней части имеет примерно форму окружности, и максимальный диаметр основания и верхней части больше максимального диаметра средней части. 3. Пузырек в сборе по п.2, отличающийся тем, что основание, средняя и верхняя часть создают форму, сходную с катушкой. 4. Пузырек в сборе ...

УСТРОЙСТВО, ИМЕЮЩЕЕ ПРОТЫКАЕМУЮ ПЕРЕГОРОДКУ, ЗАПОЛНЯЮЩУЮ ИГЛУ И ПРОТЫКАЕМУЮ КРЫШКУ, И СВЯЗАННЫЙ С НИМ СПОСОБ

... 1. Устройство для хранения вещества, содержащеегерметично изолированную камеру;первую протыкаемую перегородку, сообщающуюся с камерой, при этом первая перегородка выполнена с возможностью протыкания посредством первой иглы или подобного инъекционного элемента для заполнения через нее камеры веществом; ивторую протыкаемую перегородку, выполненную с возможностью перемещения между (i) первым положением, в котором по меньшей мере участок второй протыкаемой перегородки отстоит от первой протыкаемой перегородки для обеспечения возможности первой иглы или подобного инъекционного элемента проткнуть первую протыкаемую перегородку, не протыкая вторую протыкаемую перегородку, и дальнейшего обеспечения возможности заполнения камеры веществом и (ii) вторым положением, в котором указанный по меньшей мере участок второй протыкаемой перегородки лежит сверху и герметично изолирует образовавшееся в результате инъекции отверстие в первой протыкаемой перегородке после извлечения из нее первой иглы или подобного ...

ДОЗИРОВАНИЕ ЖИДКОСТЕЙ И СПОСОБЫ ДОЗИРОВАНИЯ ЖИДКОСТЕЙ

АДАПТЕР ЛУЕР ЛОК

НАБОР И СПОСОБ ПРИГОТОВЛЕНИЯ РАСТВОРА ДЕГАРЕЛИКСА

... 1. Набор для приготовления раствора дегареликса для введения пациенту, включающий:первую камеру, содержащую предопределенную массу лиофилизированного дегареликса;вторую камеру, содержащую предопределенный объем воды для инъекций;средство для переноса воды для инъекций в первую камеру;автоматическую мешалку, включающую адаптер для присоединения первой камеры, для перемешивания содержимого первой камеры с получением раствора дегареликса; исредство для подкожной доставки раствора дегареликса пациенту.2. Набор по п.1, где первая камера определена первым флаконом, и вторая камера определена вторым флаконом, причем указанный набор дополнительно включает:шприц для обеспечения переноса воды из второго флакона в первый флакон, иадаптеры для первого и второго флаконов для обеспечения безыгольного соединения каждого флакона со шприцем, который позволяет отбирать раствор, полученный в первом флаконе, и который можно соединить со средством для подкожной доставки раствора дегареликса пациенту.3. Набор ...

СИСТЕМА ПЕРЕМЕЩЕНИЯ СОДЕРЖИМОГО КОНТЕЙНЕРОВ

УСТРОЙСТВО ДЛЯ СОЕДИНЕНИЯ ЕМКОСТИ С КОНТЕЙНЕРОМ И СОЕДИНИТЕЛЬНЫЙ БЛОК, СОДЕРЖАЩИЙ ТАКОЕ УСТРОЙСТВО

КОНТЕЙНЕР ДЛЯ МЕДИЦИНСКИХ ЖИДКОСТЕЙ

... 1. Контейнер для медицинских жидкостей, содержащий множество камер для содержания медицинских жидкостей, разделенных перегородками с возможностью образования сообщения, и резервную выпускную камеру, содержащую выполненный в ней выпускной канал для жидкого лекарства, при этом контейнер для медицинских жидкостей содержит непроницаемый для жидкости разделительный участок для непроницаемого для жидкости разделения камер для содержания жидких лекарств между собой, и проницаемый для жидкости разделительный участок для проницаемого для жидкости разделения между, по меньшей мере, одной из камер для содержания жидких лекарств и резервной выпускной камерой. 2. Контейнер для медицинских жидкостей по п.1, в котором непроницаемый для жидкости разделительный участок и/или проницаемый для жидкости разделительный участок образуют состояние сообщения, получающееся в результате повышения давления в камере для содержания жидкого лекарства. 3. Контейнер для медицинских жидкостей по п.1, в котором проницаемый ...

Предохранительное устройство для соединения шприца с горлышком флакона или с трубкой

Изобретение относится к устройству для присоединения флакона, содержащего лекарство, к шпрмцу, игла которого размещается в закрытой полости, определяемой устройством, из которой игла может высунуться путем сдвигания отдельных состав-ляющих частей устройства вдоль друг друга. Изобретение позволяет повысить надежность при соединении за счет предотвращения преждевременного, перемещения составных частей устройства. Для этого, когда в соответствующем гнезде, предусмотренном в устройстве, флакона 11 нет, из одного из корпусов устройства выступает удлиненный гибкий отросток 13, имеющий по меньшей мере один выступ 14, который выступает в указанное гнездо и" на который флакон 11 нажимает, когда он вставляется в гнездо, отгибая отросток 13 наружу. Перед свободным концом отростка.13 расположен выполненный недругом корпусе стопорный зубец 15. Если s гнездо устройства флакон не вставлен, различные части устройства вдоль друг друга переместиться не могут, так как свободный конец гибкого отростка 13 входит ...

Transfer- und Entnahmespike

FLÜSSIGKEITSABGABEVORRICHTUNG MIT EINGEBAUTER PHIOLENBEFESTIGUNG ODER EINGEBAUTEM PHIOLENADAPTOR

Vorrichtung zum Aufbewahren und Ausgeben von flüssigen Produkten

VORRICHTUNG ZUM ZUSAMMENBRINGEN VON STOFFEN, WIE ARZNEIMITTELN, MIT EINER FLUESSIGKEIT.

Flexibler, dichter Mehrkammerbeutel

Zweikammer-Spritzampulle

NADELLOSE ZUGRIFFSVORRICHTUNG FÜR EIN MEDIZINFLÄSCHCHEN

VORRICHTUNG ZUM MISCHEN UND ABGEBEN VON ZWEI SUBSTANZEN IM STERILEN ZUSTAND

Device with a daily medicament depot for low-pain injection

The invention relates to a device with a daily medicament depot for low-pain injection. The device filled with a medicament can also be worn on the body, has a low weight and is built on the fountain-pen principle. It comprises a dust-proof, thermally insulating casing with an exchangeable, multi-layer, disinfecting, sterile fumigation pad, an inert glass or plastic cylinder with an outside that is firmly gripped, a teflon-coated piston rod and a teflon-coated metal cone, as well as a tuned optical and acoustic display system for the individual determination of the amount to be injected. The tuned optical system has a graduation in units of medicament on the unilaterally flattened threaded spindle which correlates with the medicament volume of the syringe. The acoustic system is a bayonet closure with a marking spring extending in a sound space on the unilaterally flattened threaded spindle. The fumigation pad is also used to disinfect the injection site. The puncturing direction can be ...

GLEITENDE UND ABDICHTENDE WIEDERHERSTELLUNGSANORDNUNG.

Transfervorrichtung, insbesondere für medizinische Fluids

Überleitungsgerät zum Mischen von in unterschiedlichen Behältern befindlichen Medikamenten

Injektionsstelle

Stumpfer Einstechdorn.

SPRITZENZUBEHÖR UND VERFAHREN FÜR DEN TRANSFER LUFTEMPFINDLICHER MATERIALIEN

Vorrichtung (110) zum Transferieren von Fluid (560-2), das in einer Spritze (120) enthalten ist, wobei die Vorrichtung aufweist:eine Luftschleusenkomponente (140) mit einem zylindrischen Körper, wobei der zylindrische Körper ein erstes Ende, ein zweites Ende und ein Hohlrohr aufweist, das zwischen dem ersten Ende und dem zweiten Ende angeordnet ist, wobei das Hohlrohr eine Innenfläche und eine Außenfläche hat;eine ringförmige Öffnung (242) am ersten Ende des zylindrischen Körpers;eine Gaseinlassöffnung (150) von der Außenfläche des Hohlrohrs zur Innenfläche des Hohlrohrs;eine Gasauslassöffnung (160) von der Innenfläche des Hohlrohrs zur Außenfläche des Hohlrohrs;ein nach innen weisendes luftdichtes Material (245), das mit der Innenfläche des Hohlrohrs verbunden ist; undein Septum (250), das mit dem zweiten Ende des zylindrischen Körpers verbunden ist.

Catheter set comprising a film pack with a tubular holder containing a flexible urinary catheter, has guiding elements on the outer surface of the pack along the course of the catheter holder

A catheter set (1) comprising a film pack (2), a urinary catheter (7) with a flexible shaft (9) and a tip (8), kept in an essentially tubular space (3) with an outlet (11) for the catheter at the tip end of the space (3), in which the outer surface (15) of the pack (2) is provided in at least one section of the catheter space (3) with guiding elements (14a, 14b etc.) which at least partly follow the course of the catheter space (3) in its longitudinal direction.

Mehrkammerbeutel

Vorrichtung zum Öffnen einer Leitung

Verbinder mit Verriegelungsring für eine Phiole

Behälter mit einem Luer-Filter zur Verabreichung eines Arzneistoffes

Vorrichtung zur Entnahme einer Flüssigkeit aus einer Glasampulle

Anschlusseinheit für eine Blutbehandlungsmaschine zum Anschließen der Blutbehandlungsmaschine an einen externen Behälter und Blutbehandlungsmaschine mit einer derartigen Anschlusseinheit

Die vorliegende Erfindung betrifft eine Anschlusseinheit für eine Blutbehandlungsmaschine zum Anschließen der Blutbehandlungsmaschine an einen externen Behälter mit einer maschinenseitigen Leitung welche dazu ausgelegt ist mit der Blutbehandlungsmaschine fluidisch verbunden zu werden, einer behälterseitigen Leitung, welche dazu ausgelegt ist mit dem Behälter fluidisch verbunden zu werden und einem fest mit der maschinenseitigen Leitung und der behälterseitigen Leitung verbundenen Aufsatz, welcher dazu ausgelegt ist an einem Anschlussstutzen des externen Behälters lösbar montiert zu werden, um den externen Behälter fluidisch mit der Blutbehandlungsmaschine zu verbinden; und eine Blutbehandlungsmaschine mit einer derartigen Anschlusseinheit.

AUTOKLAVIERBARE, NICHT KLEBENDE, HEISSIEGELBARE POLYMERMISCHUNGEN ZUR HERSTELLUNG VON FOLIEN AUS EINER ODER MEHREREN SCHICHTEN

Verfahren und Vorrichtung zum Ausdrücken von Körperflüssigkeiten aus einem Einstich

Vorrichtung zum Ausdrücken von Körperflüssigkeiten aus einer angestochenen Hautfläche beinhaltend ein Gehäuse und ein Haut-Einstechmedium sowie einen Haut-Stechmechanismus zum Anwenden des Haut-Einstechmediums, um in einer Haut einen Einstich zu bilden und das Haut-Einstechmedium aus dem Einstich der Haut wieder zu entfernen sowie ein an einem Ende des Gehäuses angebrachtes Stimulatorelement wobei das Stimulatorelement dafür ausgelegt ist, um an einem angestochenen Abschnitt einer Hautoberfläche eines Benutzers herum an diesem anzugreifen, so dass das Strömen von Körperflüssigkeit gefördert wird, dadurch gekennzeichnet, dass das Stimulatorelement eine Schraubenfeder aufweist und die Schraubenfeder zum Gehäuse hin zusammendrückbar ist, wenn die Haut eines Benutzers gegen das Stimulationselement gedrückt wird.

Doppelkammerbehälter und Verfahren zu seiner Herstellung

Viele Positionen aufweisende und wiederverschliessbare Phiolenverbindung zur effizienten Übertragung von Flüssigkeit

Verfahren und Vorrichtung zum Transfer einer Substanz zwischen geschlossenen Systemen

Die Erfindung befasst sich mit einem Verfahren und einer Vorrichtung zum Transfer einer Substanz zwischen geschlossenen Systemen (G, G/Z, Z, G+G/Z), die vor dem Transfer steril konnektiert werden und voneinander steril trennbar sind und wobei Mittel zur Übertragung der Substanz vorgesehen sind. Es soll eine kontaminationsfreie Übertragung der Substanz ohne Gaseinschlüsse zwischen geschlossenen Systemen ermöglicht werden. Bezüglich des Verfahrens gelingt dies dadurch, dass die während des Transfers der Substanz auftretenden Druckdifferenzen innerhalb des Systems ausgeglichen werden. Bezüglich der Vorrichtung wird die Aufgabe dadurch gelöst, dass eine Druckausgleicheinrichtung (1) vorgesehen ist, die mit mindestens einem System (G, G/Z, Z, G+G/Z) steril strömungsverbunden ist.

Mischvorrichtung

Mischvorrichtung (10, 200, 300, 400, 500) zum Mischen einer in einem ersten Behältnis vorhandenen ersten Substanz mit einer in einem zweiten Behältnis vorhandenen zweiten Substanz umfassend – einen ersten Adapter (12, 112, 312, 412, 512) mit einer Bodenwandung (16, 116, 316, 416, 516) und einer vorzugsweise auf einem Zylindermantel liegenden zur Aufnahme des ersten Behältnisses geeigneten Umfangswandung (18, 118, 318, 418, 518), wobei von einer Seite der Bodenwandung und von der Umfangswandung zumindest abschnittweise umgeben ein Kanülenkörper (36, 136, 336, 436, 536) und von gegenüberliegender Seite der Bodenwandung ein mit dem Kanülenkörper in Verbindung stehender hohlzylindrischer Abschnitt (40, 140, 340, 440, 540) ausgehen und – einen mit dem ersten Adapter verbindbaren zweiten Adapter (14, 114, 314, 414, 514) mit einer Bodenwandung (42, 142, 342, 442, 542) und einer vorzugsweise auf einem Zylindermantel liegenden zur Aufnahme des zweiten Behältnisses geeigneten Umfangswandung (44, ...

Verfahren und Vorrichtung zum Befüllen eines Einmalinjektors

Die Erfindung betrifft ein Verfahren und eine Vorrichtung zum sterilen Befüllen eines Einmalinjektors mit einer definierten Dosis einer Injektionslösung, wobei der Einmalinjektor eine Zylinder-Kolben-Einheit mit einem Zylinder und mit einem manuell zurückziehbaren Kolben umfasst. Die definierte Dosis der Injektionslösung ist in einem Behälterinnenraum eines Behälters einer in einem Durchgangsstopfen gehaltenen Nadelspritze bevorratet. Der Zylinderinnenraum ist mit dem Behälterinnenraum durch den Durchgangsstopfen hindurch gas- und flüssigkeitsdicht verbunden. Die Zylinder-Kolben-Einheit wird durch Zurückziehen des Kolbens oder Drücken des Nadelspritzenkolbens befüllt. Mit der vorliegenden Erfindung werden ein Verfahren und eine Vorrichtung zum Befüllen eines Einmalinjektors entwickelt, bei dem ohne Zwischenwiegen oder Gefahr von Ableseungenauigkeiten der Einmalinjektor mit einer definierten Dosis einer Injektionslösung aus einer Spritze mit eingeschmolzener Kanüle befüllt werden kann.

BEHÄLTER UND VERFAHREN ZUM SPEICHERN UND MISCHEN VON MEDIZINISCHEN LÖSUNGEN

STABILIZED LIQUID MIXING SYSTEM

Needle sheath

A device for preparing a pharmaceutical or medicinal product

A device for preparing a pharmaceutical or medicinal product comprises at least one filtering nozzle 22 intended to be fitted on a syringe for aspiration of a product wherein the syringe is a fixed or removable injection needle, the filtering nozzle 22 has a first tubular part 24 for attachment to the syringe, an intermediate tubular part 26 intended to receive the needle of the syringe and having an internal diameter smaller than that of the first tubular part 24 and a flat aspiration head 28 with a free open end equipped with a filtering membrane 30. Advantageously, the device is contained in a sterile package consisting of a box (40, Fig 2) made of a plastic material and having a compartment (44, Fig 2) for accommodating the nozzle 22 and a compartment for a metallic receptacle 10 which can be used for mixing the dry product with water prior to use.

Improvements in or relating to medicament packages

... 490,020. Surgical syringes ; manufacture of medicaments. COOK LABORATORIES, Inc. Feb. 5, 1937, No. 3537. Convention date, Nov. 17, 1936. [Classes 81 (i) and 81 (ii)] A medicament package, employable in adding to injections and the like, modifying agents immediately before use, comprises a tube 1 closed at one end by a flanged or other non-slidable plug 3 and having a slidable plug 6 near the other end, the enclosed space, filled with medicament, being less than the total capacity of the tube, and the tube carrying or being adapted to carry, an end stop such as 17 which prevents the plug 6 from leaving the tube. Preferably an end stop 17 is provided at each end of a clip 10 on the tube, at least one stop being perforated for the passage of a needle. In use a modifying liquid is injected, by a needle syringe 8, into the tube 1 held in the clip 10 until the plug 6 touches the stop 17, the tube being subsequently used for example in an injection syringe similar to 8. Preferably plug 6 is spaced ...

INJECTOR DEVICE

IMPROVED PROTECTIVE SHEATH FOR A CANNULA

A protective device for enclosing the scarf (86) of a cannula (70) includes an elongated sheath (82) having a bore (71) extending through it. The cannula (70) is sealed in the bore (71) of the sheath (82) with the scarf end of the cannula (70) located within and adjacent one end of the sheath (82), which is spaced from the scarf (56). The end of the sheath adjacent the scarf end of the cannula has at least one cutout (84) portion which can receive the edge of a flexible bag or a flexible tubing connected to a Y-site for intravenous injection. A socket (92) carried by the sheath (82) at the other end of the cannula (70) has an opening through it in communication with the bore (71) through the cannula (70). The socket opening (92) tapers outwardly away from the cannula (70) for receiving a tapered nozzle on a syringe. Preferably, the sheath (52) surrounds the socket (92) and carries inwardly extending ears (96) which act as male threads for engaging internal threads in a skirt around the ...

Methods and apparatus for expressing body fluid from an incision

Method and apparatus for producing foam

BLOOD BAG COMMUNICATION DEVICE

... 1474648 Blood transfusion apparatus TERUMO CORP 8 July 1975 [31 July 1974] 28757/75 Heading A5R A device for use in allowing communication between blood bags comprises a connection tube 13 for connection to a bag, and a communication pipe 17 of hard plastics fitted into and secured to the connection tube and having an open end and a sealed portion 17a and a section of reduced wall thickness 17b about which the pipe 17 can be manually broken to provide communication between the blood bags when the tube 13 is connected to a second bag via a pipe 12 to which it is connectable. Communication pipe 17 is secured in the end of the connection tube 13 by adhesive or high frequency welding and its portion 17a preferably at the pipe end is hermetically sealed by fusion, the end of the fused section lightly contacting the inner wall of the pipe 12 to prevent the free end of pipe 17 from being brought to abutment with the fixed end by blood flow from bag 11 to a second bag (14) Fig. 2, (not shown).

APPARATUS FOR MIXING TWO SUBSTANCES

Vial

There is disclosed a vial having a cap ordinarily closed by a one-way valve and capable of being engaged by the barrel of a hypodermic syringe to enable the syringe to be charged with fluid from the vial when inverted. Preferably the one-way valve is a spring-pressed ball. Preferably the cap is externally screw threaded to mate with a screw threaded syringe. The arrangement minimises contamination for multi-dose vials without the possibility of the syringe being contaminated with latex.

Closure member with septum

A medical injection device comprising a container having an inner storage for holding a fluid, a closure member having a septum barrier that provides a seal for the fluid in storage, a piston having a hollow needle that pierces the septum when pressure is applied to the rear of said container providing a flow path for said liquid. Preferably, the piston may have one or more seals that may be coated, constructed from one or more materials that includes elastomer blend, thermoplastic elastomer or a polymer. Preferably the inner storage will be pre-filled or have a method for re-filling. Preferably the combination of seals above the closure member septum will provide sterility during storage. Further embodiments will preferably include a modular dispenser for use with a smart phone, and a wearable device.

Additive transfer unit

An additive transfer unit for transferring a measured volume of a liquid medicament into an evacuated container comprises a liquid storage container 10, a rigid disc 24 closing the mouth of the container, a rigid piercing member 30 formed integrally with the disc and having a passageway 32, a penetrable protective tip 48 providing a seal over a needle point 31 on the piercing member, and a metal closure 42. An elastic sealing means 34 around and contiguous the outside diameter of the disc provides, with the disc, a fluid-tight seal over the mouth of the container, the disc including a cylindrical hub 50 to stabilize the sealing means against the metal closure. The protective tip 40 includes a portion deflecting radially outwardly of the piercing member in response to a positive pressure differential in the interior of the container, thereby venting a portion of the container contents into a cavity between the metal closure and piercing member. In use, point 31 pierces tip 40 which slides ...

A transfer device and dispensing system for the transfer of aliquots from a container of fluid

A transfer device for withdrawal of aliquots from a container of bulk solution is provided with a body having a tapered chamber, a first passage venting the smaller end of the chamber to the surrounding air, a second passage communicating at one end with the larger end of the chamber, and a third passage having one end for withdrawal of fluid therefrom. A tapered valve element is received within the chamber for movement between first and second conditions in response to changes in the presence differential between the first and second passages. The first condition provides a fluid seal between the first and second passages by engagement of the valve element with the walls of the chamber for pressures within the second passage greater than that within the first passage, and the second condition provides a fluid path from the first passage to the second passage for pressures within the second passage somewhat less than that within the first passage. The device further includes structure placing ...

LIQUID CONTAINMENT SYSTEMS

Automatic infusion device

... 1,114,238. Hypodermic devices. S. J. SARNOFF. 31 Jan., 1967 [7 Feb., 1966], No. 4664/67. Heading A5R. An automatic infusion device comprises a syringe containing a liquid medicament and includes means for expelling the medicament from the syringe, the syringe either being connected (Figure 6, not shown) by a conduit to a restriction (92) of fixed size, a drop meter (90), and to an hypodermic needle (34), in that order, or being connected (Figure 4) to a second similar syringe containing a diluent and arranged such that the diluent can be expelled from the second syringe into the first and then the commingled medicament and diluent can be expelled for infusion through a needle. As shown, in the device comprising two syringes, each syringe includes a spring 76, 80 able to move a piston 64 to expel the contents of the syringe into a conduit, each piston having a rod 66 formed with a notch 74 which enengages the syringe end stopper so that, by removing a pin 78 and moving the rod slightly sideways ...

LIQUID CONTAINERS

Medicament dispenser

Improvements in or relating to hypodermic syringes

APPARATUS FOR CONTACTING MATERIAL SUCH AS A DRUG WITH A FLUID

LIQUID RESERVOIR DRAINAGE DEVICE

Syringe unit

... 800,455. Syringes. MERCK & CO., Inc. Sept. 6, 1955 [Sept. 15, 1954], No. 25538/55. Class 81 (2). [Also in Group XVII] A syringe unit comprises two containers 1, 5, one of which has a nozzle 2 insertable into the nozzle 6 of the other, the two nozzles forming a spigot-and-socket joint which is moisture-tight and airtight and provides a passageway between the interiors of the containers, one of which is squeezable to eject the contents when separated from the other. A collapsible container 1 for a solid, powdered or crystalline ingredient is made of tin, tin-coated lead, aluminium or plastic and has a rigid nozzle 2. A resilient container 5 for a liquid ingredient is made of rubber or polyethylene and has a rigid nozzle 6. After removing a cap (not shown) from each nozzle 2, 6, one nozzle 2 is fitted into the other nozzle 6, the nozzles having complementary tapers. The resilient container 5 is squeezed to eject liquid into the collapsible container 1. On release, the resilient container 5 ...

INFUSORS FOR USE IN TRANSFERRING MEDICAMENTS

Syringe with integrally formed piercing member and luer slip.

Improvements relating to luer connectors.

A leur connector comprising a luer connectable to a syringe and which extends a sharpened en capable of being driven through a puncturable vial closure to thereby puncture the closure; a luer support, mountable on a vial, and which initially supports the luer in a first position in which the sharpened end of the conduit is pointed toward the closure; a leur driver such that movement of the driver relative the supporth causes the luer to be driven so that the sharpened end punctures the closure and enters the vial. The leur connector facilitates connection of a posdermic syringe to the vial.

Injection cartridge filling apparatus

ADAPTOR FOR COUPLING WITH A MEDICAL CONTAINER

Injection cartridge filling apparatus

Novel device

Adaptor for coupling with a medical container

Automatic mixing device and delivery system

Syringe with integrally formed piercing member and luer slip.

Novel device.

Injection cartridge filling apparatus

Adaptor for coupling with a medical container

Injection cartridge filling apparatus

Reservoir filling aid for a medical pump

A reservoir filling aid for a reservoir of a medical infusion pump is disclosed. The reservoir filling aid comprises a main body for supporting the reservoir during the filling of the reservoir with a medical serum and a supply vial adapter end positioned at a first end of the main body. The supply vial adapter end comprises a plurality of flexible tabs extending from the supply vial adapter end for interfacing with a supply vial containing the medical serum and a shaped ring for housing the plurality of flexible tabs and the supply vial while in a closed configuration to establish a fluid connection between the supply vial and the reservoir. The interior of the supply vial adapter end may also have a spiral track for additional security. A removable adapter may be fitted on the top of small supply vials.

Syringe Actuating Method And Assembly

A syringe, defined by a cylinder and by a piston slidingly engaged in the cylinder itself, is actuated after having inserted the cylinder within a gripper and having axially fed the syringe through the gripper so as to move an outer flange of the cylinder into contact with the gripper and/or the piston in a stop position within the cylinder.

Syringe drive device

A syringe drive device 1 includes a cylinder holding section 3 configured to detachably hold a cylinder 201, a piston manipulating section 4 detachably coupled with a piston, and a piston drive section 5 including racks 31 A and 31 B coupled with the piston manipulating section 4 and configured to move the piston manipulating section 4 so that a piston 202 is moved in a push-in direction or a pull-out direction. A cylinder 200 A having a given capacity (for example, 50 cc) is directly loaded in the syringe drive device 1 with no adapter therebetween. A syringe 200 C having a different capacity (for example, 20 cc) is loaded in the syringe drive device 1 by means of a cylinder adapter 81 and a piston adapter 82.

Fluid safety dispenser

A fluid safety dispenser system having a fluid storage container keyed to a fluid dispenser. The container having a valve body positionable in the opening of the container, the valve body having a plug member biased to allow fluid passage through the opening of the container when in a displaced position and to eliminate fluid passage through the opening of the container when the plug member is in a seated position. The keyed fluid dispenser assimilates a syringe and is releasably securable to the valve body for use in depressing the plug member by movement of a leaf spring when the keyed fluid dispenser is in position. The keyed fluid dispenser has indicia to provide for exact measurement and can be temporarily coupled to the container to provide ease of fluid transfer.

Systems and methods for preparing autologous fibrin glue

A method of regenerating tissue in a living organism. The method includes the act of contacting an affected area of the living organism with a solid-fibrin web, the solid-fibrin web comprising platelets that release growth factors about one minute after contact to regenerate the tissue in the living organism.

Automated Reservoir Fill System

An automated reservoir filling system for a portable medical device is disclosed. The system includes a vial sealed by a septum partially filled with a liquid and a gas occupying a headspace. The system further includes a reservoir with a volume defined between a reservoir septum and a plunger head. The plunger head is coupled to a plunger arm which is further coupled to a drive system. Further included is a transfer system with a vial end that pierces the vial septum and remains in contact with the liquid, and a reservoir end that pierces the reservoir septum and remains in the reservoir volume. A controller coupled to the drive system to actuates the drive system automatically drawing fluid from the vial to the reservoir through the degas system.

Device for removing fluids from vials

The invention relates to a device for removing a fluid from at least one container ( 300 ), for example, from a vial, that has a seal that can be punctured. The device comprises a base body ( 210 ), in which a fluid channel is formed. In order to reduce the lost volume, a pin-shaped insertion element ( 250 ) that reduces the cross-section of the fluid channel is inserted into the fluid channel through an insertion opening. Locking structures ( 262, 263 ) that retain the container on the device in a removal position and in a storage position different therefrom can be provided so that the container can be stored on the device without the seal being punctured accidentally. Such a device can be used in particular to fill an applicator ( 100 ) having one or more fluid reservoirs from one or more vials.

System and Method for Intermixing the Contents of Two Containers

A system and method for intermixing the contents of two containers. The system includes a first container, a second container, and a connector for providing fluid communication between the first and second containers. The connector includes at least one resilient retention member for securing the first container to the connector. In addition, the connector accommodates standard vials containing, for example, medicaments, and prevents the unwanted discharge of the contents of the vial into the environment.

Systems and methods for safe medicament transport

A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution.

Multi-chamber container with seal breach detection

A container having multiple compartments formed by frangible seals in the interior chamber of the container is disclosed. The container comprises an indicator adapted to provide an indication that a seal breach between the chambers has occurred. Methods of forming a container having a seal breach detection indicator are also disclosed.

Device

The present application is directed to devices. The device may used for connecting a closed receptacle and a container, such as a syringe.

CLOSED FLUID TRANSFER SYSTEM

A closed fluid transfer system for fluidly interconnecting a syringe to any one of a patient I.V. set, a vial and an I.V. bag, is provided and includes a first adapter defining a lumen and supporting a seal across a first end of its lumen, the first adapter supporting a rear end of a needle within the lumen, wherein the seal is movable relative to the needle such that a tip of the needle penetrates through the seal; and a second adapter defining a lumen and supporting a seal across a first end of its lumen; wherein when the second adapter is coupled to the first adapter, the second adapter seal abuts the first adapter seal and moves the first adapter seal relative to the tip of the needle such that the tip of the needle penetrates through the abutting first adapter seal and second adapter seal. 1. A closed fluid transfer system for fluidly interconnecting a syringe to at least one of a patient I.V. set , a vial and an I.V. bag , the closed fluid transfer system comprising: a housing defining an open distal end and an open proximal end, the housing defining a pair of opposed longitudinally extending slots opening from the open distal end of the housing, the housing including a pair of opposed longitudinally extending ribs projecting from an inner surface thereof;', 'a base supported in the open proximal end of the housing and including a luer connector;', 'a collar slidably and rotatably supported in the housing, the collar defining a longitudinal opening therethrough, the collar defining a pair of opposed L-shaped tracks formed in an outer surface thereof and configured to receive a respective longitudinally extending rib therein, the collar defines a pair of opposed helical tracks opening from a distal surface of the collar, the opposed helical tracks being aligned with a respective slot of the housing when the collar is in a distal-most position;', 'a shuttle slidably extending through longitudinal opening of the collar, the shuttle defining a lumen extending ...

Drug solution delivery device for medical use

A cylindrical body ( 30 ) that is inserted into a drug solution container ( 70 ), a connection port ( 15 ) to which a syringe ( 40 ) is connected, and a connector ( 50 ) that is connected to a port ( 110 ) of an infusion bag ( 100 ) communicate with a cavity ( 11 ) of a delivery device main body ( 10 ). A first check valve ( 21 ) that functions to permit the flow of drug solution toward the cavity from the drug solution flow path and restrict the flow of drug solution in the opposite direction is provided on a flow path between a drug solution flow path ( 31 ) of the cylindrical body and the cavity. A second check valve ( 22 ) that functions to permit the flow of drug solution toward the connector from the cavity and restrict the flow of drug solution in the opposite direction is provided on a flow path between the connector and the cavity. Drawing a plunger ( 45 ) of the syringe in and out enables a drug solution ( 72 ) contained in the drug solution container to be efficiently transferred to the infusion bag.

System and method for mixing the contents of two containers

A system for mixing the contents of a first container and a second container. The system includes the first container that has container body with an opening fluidly connected to a cavity defined by the container body, a first substance contained in the cavity, and a stopper sealing the opening. The second container includes a port assembly including a port housing connected to the second container and a retainer constructed to connect to the first container. The retainer is configured to rotate and move axially relative to the port housing, wherein relative rotation between the port housing and the retainer causes the retainer to move axially relative to the port housing. The port assembly further includes an axially fixed actuator constructed to force the stopper into the first container when the retainer is rotated relative to the port housing. 1. A system for mixing the contents of a first container and a second container , the system comprising:a first container comprising a container body comprising an opening fluidly connected to a cavity defined by the container body, a first substance contained in the cavity, and a stopper sealing the opening;a second container having a cavity containing a second substance; anda port assembly comprising a port housing connected to the second container, and a retainer constructed to connect to the first container, wherein the retainer is configured to rotate and move axially relative to the port housing, wherein relative rotation between the port housing and the retainer causes the retainer to move axially relative to the port housing, and wherein the port assembly further comprises an axially fixed actuator constructed to force the stopper into the first container when the retainer is rotated relative to the port housing.2. The system of claim 1 , wherein a first set of threads are formed on a surface of the port housing and wherein a second set of threads are formed-on a surface of the retainer claim 1 , the first and ...

System and method for mixing the contents of two containers

A system for mixing contents of a first container with contents of a second container. The system includes a first container, a second container, a device for establishing fluid communication between the first container and the second container, and a hanger for hanging the system, wherein the hanger is operable only when fluid communication between the first container and the second container has been established. The system can be used in a method for preventing medication delivery errors.

System and method for mixing the contents of two containers

A port assembly for establishing fluid communication between a first container and a second container. The port assembly includes a port housing for connection to a second container, and a retainer for connection to a first container, wherein the retainer rotates relative to the port housing and is constructed to move axially within the port housing. An actuator is axially fixed within the port housing and forces a stopper associated with a first container into a first container when the retainer moves axially within the port housing upon rotation of the retainer relative to the port housing. The assembly is configured to establish fluid communication between a first container and a second container upon rotation of the retainer relative to the port housing. 1. A port assembly for establishing fluid communication between a first container and a second container , the port assembly comprising:a port housing constructed for connection to a second container, the port housing having a first end and a second end;a retainer constructed for connection to a first container, wherein the retainer rotates relative to the port housing, the retainer constructed to move axially within the port housing toward the second end of the port housing upon rotation of the retainer relative to the port housing; andan actuator axially fixed within the port housing, the actuator constructed to force a stopper associated with a first container into a first container when the retainer moves axially within the port housing upon rotation of the retainer relative to the port housing.2. The port assembly of claim 1 , wherein the assembly is configured to establish fluid communication between a first container and a second container upon rotation of the retainer relative to the port housing.3. The port assembly of claim 1 , wherein the port housing comprises first threads and the retainer comprises second complementary threads claim 1 , the first and second threads being constructed to cause the ...

Clamp and blood bag system

A clamp for a blood bag system includes a protrusion section which presses a tube, a locking section having a first engagement section and a second engagement section that form therebetween an engagement groove in which the protrusion section is positioned and by which engagement can be made, a first engagement release section which releases an engaged state between the first engagement section and the protrusion section; and a second engagement release section which releases an engaged state between the second engagement section and the protrusion section.

CONNECTOR AND CONNECTOR ASSEMBLY

A first connector includes a first connector main body configured from an outer tube of cylindrical shape, an inner tube of cylindrical shape, and a hub disposed at a proximal end portion of the outer tube, a hollow needle supported on the hub, a first sealing member supported on the inner tube, a coil spring serving as puncturing portion biasing means for biasing the first sealing member toward a distal direction, and a clamping member disposed upon the outer tube. Upon an inner periphery portion of the proximal end portion of the outer tube, a pawl is formed so as to project to the inner side. Upon an outer periphery portion of a large diameter portion of a main body portion of the hub, a plurality of ratchet teeth which are engageable with the pawl of the outer tube are formed so as to project toward the outer side. 1. A connector , comprising:an outer tube;a hub disposed at a proximal end portion of the outer tube for rotation around an axis of the outer tube with respect to the outer tube, wherein the hub includes a main body portion inserted in the outer tube, a connecting portion having a proximal end side to which a medical device having a screw threaded portion is to be connected, and a projecting portion for being screwed with the screw threaded portion;separation preventing means for preventing separation of the hub from the outer tube; androtation blocking means having a rotation blocking function for blocking the rotation of the hub in only one of a forward direction and a backward direction;wherein the rotation blocking means includes a first engaging portion provided at the proximal end portion of the outer tube and a second engaging portion provided on the hub and engageable with the first engaging portion,wherein a direction in which the hub is urged to rotate by rotational torque applied to the hub when the medical device is rotated with respect to the hub to screw the screw threaded portion with the projecting portion and a direction of the ...

Medical Drug Solution Container

The present invention is a medical drug solution container () which is formed of a plastic film including seal layers. This medical drug solution container includes a plurality of drug solution storing chambers () that are divided so as to be able to communicate; a spare discharge chamber () that is formed with a discharge port of a drug solution; liquid-tight dividing means () that liquid-tightly divides the plurality of drug solution storing chambers () from each other; and non-liquid-tight dividing means () that non-liquid-tightly divides at least one () of the plurality of drug solution storing chambers () from the spare discharge chamber (), the non-liquid-tight dividing means () has fine pores () through which a trace amount of the drug solution or water included in the drug solution can penetrate to the spare discharge chamber (), and seals the seal layers so as to be peelable, and the seal layers includes one or more kinds of resins of which the melting point is 130° C. or higher and which is selected from a group consisting of homo-polypropylene, random-polypropylene, and high-density polyethylene. 1. A medical drug solution container which is formed of a plastic film including seal layers , comprising:a plurality of drug solution storing chambers that are divided so as to be able to communicate;a spare discharge chamber that is formed with a discharge port of a drug solution;liquid-tight dividing means that liquid-tightly divides the plurality of drug solution storing chambers from each other; andnon-liquid-tight dividing means that non-liquid-tightly divides at least one of the plurality of drug solution storing chambers from the spare discharge chamber,wherein the non-liquid-tight dividing means has fine pores through which a trace amount of the drug solution or water included in the drug solution can penetrate to the spare discharge chamber, and seals the seal layers so as to be peelable, andwherein the seal layers includes one or more kinds of resins ...

CONTAINERS FOR COMPOSITIONS COMPRISING MELOXICAM

A plastic container containing a pharmaceutical composition comprising benzoic acid or a derivative or a pharmaceutically acceptable salt thereof and a COX-inhibitor of the oxicam-type or a pharmaceutical acceptable salt thereof, wherein the container material selected from one or more members of the group consisting of a homopolymer of polypropylene (PP), a copolymer of polypropylene (PP), a homopolymer of polyethylene terephthalate (PET) and a copolymer of polyethylene terephthalate (PET), and optionally one or more non-polymeric components. 1. A pharmaceutically acceptable container for containing a pharmaceutical composition including sodium benzoate , the container being formed of container material effective to prevent significant loss of the sodium benzoate during storage , wherein the container material is selected from the group consisting of a homopolymer of polypropylene (PP) , a copolymer of polypropylene (PP) , a homopolymer of polyethylene terephthalate (PET) and a copolymer of polyethylene terephthalate (PET).2. The container according to including a pharmaceutical composition comprising sodium benzoate stored in the container.3. The plastic container according to claim 2 , wherein the sodium benzoate is present in the composition in a concentration range of 0.8 mg/ml to 2.0 mg/ml.4. The container according to claim 2 , wherein the composition further comprises an oxicam-type COX-inhibitor or a pharmaceutical acceptable salt thereof claim 2 , the oxicam-type COX-inhibitor being selected from the group consisting of meloxicam claim 2 , piroxicam claim 2 , lornoxicam claim 2 , tenoxicam claim 2 , droxicam claim 2 , and isoxicam.5. The container according to claim 2 , wherein the composition further comprises meloxicam or a pharmaceutical acceptable salt thereof.6. The container according to claim 2 , wherein the container material does not include high-density polyethylene (HDPE) claim 2 , low-density polyethylene (LDPE) claim 2 , or polycarbonate (PC). ...

SYRINGE KIT FOR MIXING TWO MEDICINAL FLUIDS

A syringe kit for mixing two medicinal fluids includes first and second barrels adapted to contain medicinal fluids therein. The first barrel includes a connecting tube portion at a tip portion thereof having a male screw on an outer periphery, and an inner tapered surface on an inner periphery. The second barrel includes a nozzle portion at a tip portion thereof having a screw tube portion with a female screw on an inner periphery thereof freely engageable with the male screw, and an outer tapered surface fitting to the inner tapered surface on the inner periphery. At least a surface of the male screw and the outer periphery of the connecting tube portion of the first barrel, or a surface of the female screw and the inner periphery of the screw tube portion of the second barrel are roughened to a surface roughness in a range between Ra1.0 and Ra2.0. 1. A syringe kit for mixing two medicinal fluids , comprising:a first barrel adapted to contain a medicinal fluid therein, and including a first plunger, and a connecting tube portion at a tip portion thereof having a male screw on an outer periphery and an inner tapered surface on an inner periphery thereof, anda second barrel adapted to contain another medicinal fluid therein, and including a second plunger, and a nozzle portion at a tip portion thereof having a screw tube portion with a female screw on an inner periphery thereof freely engageable with the male screw on the outer periphery of the connecting tube portion, and an outer tapered surface fitting to the inner tapered surface on the inner periphery of the connecting tube portion,wherein at least a surface of the male screw and the outer periphery of the connecting tube portion of the first barrel, or a surface of the female screw and the inner periphery of the screw tube portion of the second barrel are roughened to a surface roughness in a range between Ra1.0 and Ra2.0.2. A syringe kit according to claim 1 , wherein the inner tapered surface of the ...

AUTOMATIC MIXING DEVICE AND DELIVERY SYSTEM

A wet/dry auto-mixing injector having a mixing device containing at least one microfluidic channel for mixing or dissolving a dry component with a wet component stored in the injector device. 1. An automatic injection device containing a pre-loaded charge of medicament for automatically self-administering the medicament upon actuation thereof , the device comprising:a housing assembly having an interior chamber, the interior chamber including a wet compartment containing a wet medicament component;a seal structure placed at an orifice of the interior chamber, the seal structure being initially in a sealing condition that maintains the wet component within the interior chamber, the seal structure being converted to a mixing condition as a result of activation of the device;a mixing assembly comprised of at least one microfluidic channel, in fluid communication with the interior chamber when the device is activated, and wherein a portion of the mixing assembly contains a dry medicament component configured to mix with the wet medicament component when the seal structure is converted to mixing condition;a delivery assembly that dispenses the charge of medicament from the housing;an activation assembly carried by the housing and including a stored energy source, wherein activation of the activation assembly releases the stored energy from the stored energy source, and wherein the release of the stored energy causes a) the seal structure to be converted from the sealing condition to the mixing condition and thereby permit the wet component to pass there through, b) the wet component to be forced through the mixing assembly to facilitate mixing of the wet and dry components, and c) force the mixed components through the delivery assembly.2. The automatic injection device of claim 1 , wherein the dry component is partially soluble in the wet component3. The automatic injection device of claim 1 , wherein the microfluidic channel of the mixing device includes a plurality of ...

Multi-Dose Vial and Method

A vial for storing multiple doses of a substance to be dispensed into one or more syringes or other delivery devices. The vial has a body, a variable-volume storage chamber within the body for storing multiple doses of the substance therein, and a one-way valve connectable in fluid communication with a syringe or other delivery device. The one-way valve is moveable relative to the body between first and second positions (i) one of which permits the valve to open so that substance from the variable-volume storage chamber can flow therethrough and into the syringe or other delivery device connected in fluid communication therewith, and (ii) one of which prevents the valve from opening. 1. A device for storing multiple doses of a substance to be dispensed into one or more syringes or other delivery devices , comprising:a body;a storage chamber within the body for storing multiple doses of the substance therein; anda one-way valve connectable in fluid communication with a syringe or other delivery device and moveable between first and second positions, and having a closed position preventing substance from passing therethrough and an open position permitting substance to pass therethrough;wherein, in the first position the one-way valve is prevented from opening into the open position and substance from the storage chamber cannot pass therethrough, and in the second position the one-way valve is permitted to open into the open position so that the one-way valve permits substance from the storage chamber to flow therethrough and into the syringe or other delivery device connected in fluid communication therewith.2. A device as defined in claim 1 , wherein the one-way valve is configured to substantially prevent any fluid flow in a substantially opposite direction claim 1 , from the syringe or other delivery device claim 1 , therethrough claim 1 , and into the storage chamber.3. A device as defined in claim 1 , wherein the storage chamber comprises a variable-volume ...

Medical Device Connector

The present invention relates to a medical device connector for connecting a piercing device ( 3 ), with a vial ( 2 ) comprising a base member. A plurality of grip members ( 50 ), each grip member ( 50 ) comprising a distal end (D) and a proximal end (P) and each comprising a wedge portion ( 61 ) adapted to temporarily or permanently lock the medical device connector ( 1 ) to the vial ( 2 ). The base member ( 30 ) further comprises a plurality of flanges ( 40 ), wherein the proximal ends (P) of the grip members ( 50 ) are arranged to the flanges ( 41, 40 ). The flanges ( 40 ) extend substantially out from the periphery of the base member ( 30 ) in a direction substantially perpendicular to the direction of the grip members, wherein the space formed between the flanges ( 40 ) of the base member ( 30 ) forms at least one grip portion. The present invention provides for a medical device connector ( 1 ) which is easy and comfortable to use, which provide good stacking capabilities and which permits a user to readily acknowledge that the medical device connector ( 1 ) is correctly assembled with the vial ( 2 ).

DEVICE FOR SEALING A VESSEL AND METHOD OF MANUFACTURING A SEALED VESSEL

A device for sealing a vessel, in particular a cartridge () or a test-tube for accommodating a freeze-dried pharmaceutical product (S), wherein the vessel () comprises at its opening end () an opening edge () and an adjoining longitudinal portion () with an evenly formed inner cross section, including a front plunger () to be positioned inside the vessel () at the longitudinal portion (), is characterized in that the front plunger () is configured to be positioned in the vessel () in a sealing state, in which the front plunger () is fully inserted in the vessel (), or in an exchange state, in which the front plunger () is inserted partly in the vessel () and partly protrudes over the opening edge () of the vessel (), wherein the front plunger () comprises sealing means that are configured to seal the inside of the vessel () against the outside when the front plunger () is positioned in the sealing state, and one or more communicating grooves () that are configured to place the inside and outside of the vessel () in communication with each other when the front plunger () is positioned in the exchange state. Furthermore, a method of manufacturing a sealed vessel () is disclosed. 1. A device for sealing a vessel , in particular a cartridge or a test-tube for accommodating a freeze-dried pharmaceutical product , wherein the vessel comprises at its opening end an opening edge and an adjoining longitudinal portion with an evenly formed inner cross section , the device comprising:a front plunger to be positioned inside the vessel at the longitudinal portion, sealing means configured to seal the inside of the vessel against the outside when the front plunger is positioned in the sealing state, and', 'one or more communicating grooves configured to place the inside and outside of the vessel in communication with each other when the front plunger is positioned in the exchange state., 'wherein the front plunger is configured to be positioned in the vessel in a sealing state, ...

MEDICAMENT ADMIXING SYSTEM

A system for mixing the contents of a first container with the contents of a second container. The second container has a port assembly for receiving the first container. The port assembly has an actuator that is constructed to access the cavity of the first container during activation of the system and to allow fluid communication between the first container and the second container. The port assembly further includes a movable plug that provides a seal for the second container. The plug is configured to move axially relative to the actuator during activation of the system, thereby opening the seal of the second container and providing fluid communication between the first container and the second container. 1. A system for mixing contents of a first container with contents of a second container , the system comprising:a first container defining a cavity and an opening thereto;a stopper positioned within the opening defined by the first container to seal the first container;a second container defining a cavity; anda port assembly attached to the second container, wherein the port assembly is configured to receive the first container, and wherein the port assembly comprises (i) an actuator constructed to access the cavity defined by the first container during activation of the system and to allow fluid communication between the first container and the second container, and (ii) a moveable plug providing a seal for the second container, wherein the moveable plug is configured to move axially relative to the actuator during activation of the system, thereby opening the seal of the second container and providing fluid communication between the first container and the second container.2. The system of claim 1 , wherein the first container comprises a first mating member configured to engage a second mating member of the port assembly.3. The system of claim 2 , wherein the second mating member comprises a retainer claim 2 , and wherein the retainer comprises a plurality ...

MEDICAMENT ADMIXING SYSTEM

A medicament container having an opening that provides access to a cavity defined by the medicament container. A stopper is sealingly positioned within the opening of the medicament container and configured to be forced into the cavity to open the medicament container. The medicament container also includes a mating member configured to mate with a complementary receiver associated with a second container to connect the medicament container to a second container. The medicament container further includes a radial seal configured to engage and seal against an interior seal wall associated with a second container prior to the stopper being forced into the cavity defined by the medicament container. A system is also provided for establishing fluid communication between a first container and a second container. The system includes a first container (e.g., a medicament container) having a radial seal, a second container, and a port assembly. 1. A medicament container comprising:an opening providing access to a cavity defined by the medicament container;a stopper sealingly positioned within the opening, wherein the stopper is configured to be forced into the cavity to open the medicament container;a mating member configured to mate with a complementary receiver associated with a second container to connect the medicament container to a second container; anda radial seal configured to engage and seal against an interior seal wall associated with a second container prior to the stopper being forced into the cavity defined by the medicament container.2. The medicament container of claim 1 , wherein the radial seal is configured to engage and seal against an interior seal wall associated with a second container when the medicament container is connected to a second container.3. The medicament container of claim 1 , wherein the radial seal comprises a radially extending annular flange.4. The medicament container of claim 1 , wherein the radial seal is located above the opening ...

CONNECTORS FOR FLUID CONTAINERS

Connector for enabling fluid transfer between a first fluid container and a second fluid container, which connector comprises a first component that is arranged to be connected to a first fluid container and a second component that is arranged to be connected to a second fluid container. The first component is arranged to be non-rotatably connected to said second component before a second fluid container is connected to said second component and/or before a first fluid container is connected to the first component. The connector comprises a locking and rotation-enabling element that is arranged to be activated once a second fluid container has been connected to said second component, and/or once a first fluid container has been connected to the first component, which locking and rotation-enabling element enables the first component and the second component to rotate freely with respect to one another. 1. A connector for enabling fluid transfer between a first fluid container and a second fluid container , the connector comprising:a first component that is arranged to be connected to a first fluid container and a second component that is arranged to be connected to a second fluid container, whereby said first component is arranged to be non-rotatably connected to said second component, or a part of the second component, and to a first fluid container before a second fluid container is connected to said second component or before a first fluid container is connected to the first component, wherein said connector comprises a locking and rotation-enabling element that is arranged to be activated once a second fluid container has been connected to said second component, or once a first fluid container has been connected to the first component, said locking and rotation-enabling element enables the first component and the second component to rotate freely with respect to one another, one of said first or second component comprises a guide portion to facilitate the ...

MEDICATION ACCESS DEVICE FOR PREVENTION OF MEDICATION RESERVOIR CONTAMINATION

A safety-engineered, one-time use, syringe adaptor-connector system restricts access to medical vials and intravenous bags (e.g., common reservoirs) using a valve and providing a barrier to inserting a needle in the reservoir. 1. A safety system for inhibiting contamination of a liquid reservoir , the system comprising:a syringe adapter configured for a one time use; anda liquid reservoir connector configured to receive a syringe adapter that has not been used.2. The safety system of claim 1 , wherein the syringe adapter is coupled to a syringe or integrated with the syringe or removably coupled to the syringe.3. (canceled)4. (canceled)5. The safety system of claim 1 , wherein the syringe adapter includes a mechanism that allows flow in one direction and prevents subsequent liquid flow after adapter removal claim 1 , wherein the syringe adapter includes a barrier configured to inhibit the syringe from receiving a needle.6. (canceled)7. The safety system of claim 1 , wherein the syringe adapter includes perforations associated with a pull tab claim 1 , which are cooperatively configured such that manipulation of the pull tab splits the syringe adapter at the perforations.8. The safety system of claim 1 , wherein the syringe adapter includes a Luer lock.9. The safety system of claim 1 , wherein the syringe adapter is configured to disassemble claim 1 , deform or split when removed from a syringe such that the syringe adapter is rendered unusable.10. The safety system of claim 1 , wherein the syringe adapter has an attachment mechanism for coupling to a syringe.11. The safety system of claim 10 , wherein the attachment mechanism includes a hinge configured to be manipulated for attachment or detachment of the syringe adapter to the liquid reservoir connector claim 10 , and the liquid reservoir connector includes a member to operate with the hinge for the attachment or detachment.12. The safety system of claim 10 , wherein the attachment mechanism includes a saw tooth ...

SAFETY DRUG HANDLING DEVICE

A drug mixed system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one syringe adaptor adapted to be attached to a syringe and to the at least one receptacle port adaptor and at least one vial adaptor adapted for connection to a vial containing a drug and adapted for connection to the at least one syringe adaptor, the system being characterized in that at least one of the receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form. 263-. (canceled) The present invention seeks to provide an improved drug mixing system, operative for use with a luer fitted hypodermic syringe, which is particularly useful in handling toxic drugs such as antineoplastic drugs.There is thus provided in accordance with a preferred embodiment of the present invention a drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one vial adaptor adapted for connection to a vial containing a drug and at least one syringe adaptor adapted to be attached to a syringe and to at least one of the at least one receptacle port adaptor and the at least one vial adaptor, the system being characterized in that at least one of the at least one receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form.There is also provided in accordance with another preferred embodiment of the present invention a drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one vial adaptor adapted for connection to a vial containing a ...

MULTIVOLUME CARTRIDGE ASSEMBLY AND METHOD OF MAKING THE SAME

A multivolume cartridge assembly having two or more internal compartments for storing and administering one or more medicinal compounds. In some embodiments, a second internal volume is positioned in the distal end of the cartridge assembly, and in other embodiments, the second internal volume is positioned in the apical end of the cartridge assembly. In some embodiments, the cartridge is configured to allow for long term storage of two or more medicinal compounds without mixing of the two or more compounds during storage. The cartridge, in some embodiments, utilizes a stopper assembly to create fluid communication between the two or more internal compartments of the cartridge and allow for mixing of the contents of the two or more compartments prior to the administration of those contents to a patient. 1. A cartridge assembly with a plurality of compartments for storing and delivering medicinal compounds comprising:a containing vessel made from a rigid material having an apical end and a distal end, the containing vessel defining an interior lumen, the interior lumen extending from the apical end to the distal end of the containing vessel, the interior lumen defining an opening on the distal end of the containing vessel and an opening on the apical end of the containing vessel and an inner surface within the containing vessel;a barrier connected to the apical end of the containing vessel that seals the apical end of the containing vessel;a connecting member on the apical end of the containing vessel configured to secure the barrier to the apical end of the containing vessel; a plugging member having a distal end and a proximal end, the plugging member configured to seal the interior lumen at the distal end of the containing vessel, a flexible wall attached to the apical end of the plugging member, wherein the flexible wall and the apical end of the plugging member define an interior volume, and', 'a tab member connected to the plugging member, the tab member ...

FLUID DELIVERY SYSTEMS, DEVICES AND METHODS FOR DELIVERY OF HAZARDOUS FLUIDS

A system for delivering fluid to a patient includes a container suitable for holding a fluid and an enclosure to shield the fluid. The system further includes a pump device capable of pumping fluid from the container and delivering the fluid to the patient, and the container adapted to be attachable to the pump device. 1. A system for delivering a fluid to a patient comprising:a container suitable for holding a fluid and comprising an enclosure to shield the fluid; anda pump device capable of pumping the fluid from the container and delivering the fluid to the patient;wherein the container is adapted to be attachable to the pump device.2. The system of wherein the fluid comprises a radiopharmaceutical fluid and the enclosure is radiation shielded.3. The system of wherein the container comprises a heating/cooling element for heating/cooling the fluid.4. The system of wherein the container is removably attached to the pump device via a release latch.5. The system of wherein the pump device comprises controls positioned on the body of the pump device to control operation of the pump device.6. The system of further comprising a remote control device associated with the pump device to control operation of the pump device.7. The system of wherein the container is disposable.8. The system of further comprising a second container removably attachable to the pump device and containing a different fluid from the fluid.9. The system of wherein the fluid comprises a pharmaceutical fluid and the different fluid comprises a diluent fluid.10. The system of further comprising a mixing device associated with the pump device for mixing the fluid and the different fluid for delivering a fluid mixture of the fluid and the different fluid to the patient.11. The system of wherein the mixing device comprises a sterile tubing set for mixing the fluid and the different fluid.12. The system of wherein the pump device is manually operated.13. The system of wherein the container is adapted to ...

BAG FOR LIQUID SOLUTIONS MIXABLE WITH ACTIVE SUBSTANCES AVAILABLE IN A SEPARATE FORM, IN PARTICULAR IN POWDER OR GEL, FOR FORMING LIQUID MEDICINAL OR LIQUID SUBSTANCES THAT ARE ADMINISTRABLE TO PATIENTS THROUGH INTERNAL INSTILLATION

A flexible bag () that is partially filled with a basic liquid solution () has a first end closure () from which a mixing tube () extends that is provided with a frangible closure cap () and a terminal () that is suitable for the connection of a container () of active substance () to be mixed with the basic liquid solution () and a second end closure () from which two dispensing tubes () extend that are provided with respective frangible closure caps (). A first dispensing tube () has a terminal () of the press type and a second dispensing tube () has a terminal () of the screw type (FIG. ). 1. A flexible bag partially filled with a basic liquid solution and having a first end closure from which a mixing tube provided with a frangible closure cap extends , and a terminal suitable for the connection of a container of active substance to be mixed with the basic liquid solution and a second end closure from which two dispensing tubes provided with respective frangible closure extend , a first dispensing tube having a press-fit type terminal and a second dispensing tube having a screw type terminal.2. The flexible bag according to claim 1 , characterized in that said first end closure is provided with holes for the connection of the bag in hanging condition.3. The flexible bag according to claim 1 , characterized in that each of said dispensing tubes is provided with a respective closure clamp.4. The flexible bag according to claim 1 , characterized in that said mixing tube is provided with a closure clamp. The present invention relates to a bag for liquid solutions that are mixable with active substances available in a separate form, in particular in powder or gel, for forming liquid medicinal or liquid substances that are administrable to patients through internal instillation.In hospital environments, there is often a need to administer to patients, by internal instillation, medicinal and nutritional substances of different kinds that are made available separately, ...

Bushing for receiving a dropper neck, and corresponding package and kit

A bushing for the preparation of a suspension or solution formed by mixing a first product with a second product, to allow a first bottle initially containing the first product to communicate with a second bottle initially containing the second product is provided.

Medicament Administration Apparatus

An apparatus for removal of premixed drugs or reconstitution of lyophilized drugs and for the injection of the reconstituted drug into the patient. The apparatus includes a syringe assembly and an adapter assembly that can be removably connected to a medicament container containing a premixed drug or lyophilized medicament. The syringe assembly of the apparatus includes a liquid chamber between the forward end of the body portion and the piston and a syringe cannula assembly. The syringe cannula assembly, which can be removably interconnected with the body portion, comprises a cannula support and a hypodermic needle sealably connected to the cannula support. The adapter assembly comprises an adapter preferably molded from a moldable plastic that includes a top wall, an adapter cannula connected to and extending from the top wall and a variety of connectors connected to the top wall for removably interconnecting the adapter with the medicament container. 1. A method for reconstituting lyophilized medicaments and for the injecting of reconstituted medicaments into the patient using an apparatus comprising a vial accessing means for interconnecting an aspirator containing a fluid with a medicament container having an interior containing a medicament , the vial accessing means including an adapter having a top wall , a resiliently deformable skirt connected to and extending from the top wall for receiving a portion of the medicament container and an adapter cannula connected to and extending from the top wall and a plurality of circumferentially spaced , buttress members defining an opening; and an assembly made up of a needle sheath having a yieldably deformable wall and a syringe connector assembly for interconnection with an aspirator , the assembly being received within the opening defined by the buttress members; said method comprising the steps of:(a) mating the adapter with the medicament container in a manner to place the adapter cannula in communication with ...

CONNECTOR, SYRINGE ASSEMBLY, AND CONNECTOR FOR MIXING

A connector is configured to be connected to a syringe assembly provided with at least one syringe having an outer cylinder with a protruding tube-shaped port, and a holder which holds the syringe. The connector includes a connector main body mountable on a container containing a medical solution; a tube-shaped fitting section protruding from the upper section of the connector main body for receiving the syringe to connect the inside of the syringe and the inside of the container when the syringe port is fitted in the fitting section; and fixing means having a lock mechanism that fixes the syringe assembly to the connector main body when the syringe port is fitted in the fitting section, an operating section to release the fixed state provided by the lock mechanism, and a push-out section that pushes out the syringe assembly when the fixing releasing operation is performed. 1. A mixing connector connectable to a medicine container , which contains medicine and which is positioned in a first port of a holder , and a liquid container , which contains liquid different from the medicine and which is positioned in a second port of the holder possessing a configuration different from the configuration of the first port , the mixing connector comprising:a support section;a double-pointed needle supported in the support section and extending over a longitudinal extent, the double-pointed needle including a first portion projecting away from the support section in a first projecting direction and terminating at a sharpened end for puncturing a stopper in the medicine container, the double-pointed needle including a second portion projecting away from the support section in a second projecting direction and terminating at a sharpened end for puncturing a stopper in the liquid container, the double-pointed needle possessing a lumen extending throughout the longitudinal extent of the double-pointed needle and opening to both the first sharpened end and the second sharpened end ...

ADAPTER

The invention relates to an adapter which comprises a base having a container attachment portion on a first side and a needle hub attachment portion on a second side opposite the first side. The adapter includes a puncturing member extending along a first axis for entering a container inserted into the container attachment portion. The adapter includes a channel extending substantially along the first axis from the needle hub attachment portion, through the base and along the puncturing member to an axial outlet at, or adjacent, a tip of the puncturing member. The adapter is configured so that a needle comprising a shaft extending from a hub can be inserted into the adapter such that the hub engages the hub attachment portion and the shaft extends through the base and within the puncturing member. 1. An adapter , the adapter comprising a base having a container attachment portion on a first side thereof and a needle hub attachment portion on a second side thereof , the first side being opposite the second side , the adapter including a puncturing member extending along a first axis for entering a container inserted into the container attachment portion , the adapter including a channel extending substantially along the first axis from the needle hub attachment portion , through the base and along the puncturing member to an outlet at , or adjacent , a tip of the puncturing member , the adapter configured such that a needle comprising a shaft extending from a hub can be inserted into the adapter such that the hub engages the hub attachment portion and the shaft extends through the base and within the puncturing member , the adapter characterised in that the outlet is an axial outlet from the puncturing member , the axial outlet extending substantially along the first axis.2. An adapter as claimed in claim 1 , in which the container attachment portion is adapted to snap fit to a vial and the puncturing member is sharpened such that it will penetrate an elastomeric ...

Medicine storage container

A liquid medicine storage container has a container body and a medicine stored in the container body. The container body includes a first space provided on the distal end, into which a liquid is injected, a second space provided more to the proximal end than the first space, for storing the medicine, and at least one guide passage that communicates the first space and the second space and that guides a liquid injected from the first space to an inner surface of the second space. The container body is configured so that the liquid guided to the inner surface is supplied to the medicine by flowing along the inner surface. A plurality of guide passages is arranged with intervals therebetween along a circumferential direction of the container body.

INFUSION PREPARATION

An object of the present invention is to provide an infusion preparation in which the Maillard reaction between an amino acid and a reducing sugar does not occur during storage and the size of fat particles in the fat emulsion does not increase during storage, and in which various types of vitamins can be incorporated in a stable manner, in spite of the fact that it is a two-chamber infusion preparation. Furthermore, even if only one of the infusions (of the infusion preparation) is administered, the patient is unlikely to develop hyperkalemia, vascular pain, or phlebitis. The present invention provides an infusion preparation containing two chambers separated by a partition that can be communicably opened, wherein a first chamber contains a first-chamber infusion containing a sugar and a fat emulsion, a second chamber contains a second-chamber infusion containing an amino acid and an electrolyte, the first-chamber infusion is substantially free of potassium, and has a relative osmotic pressure of 2.0 to 3.0, the second-chamber infusion has a potassium concentration of 40 mEq/L or less and a relative osmotic pressure of 2.5 to 3.5, and a mixture of the first- and second-chamber infusions has a potassium concentration of 16 mEq/L or more as measured upon communicably opening the partition. 1. An infusion preparation comprising two chambers separated by a partition that can be communicably opened , whereina first chamber contains a first-chamber infusion comprising a sugar and a fat emulsion;a second chamber contains a second-chamber infusion comprising an amino acid and an electrolyte;the first-chamber infusion is substantially free of potassium, and has a relative osmotic pressure of 2.0 to 3.0;the second-chamber infusion has a potassium concentration of 40 mEq/L or less and a relative osmotic pressure of 2.5 to 3.5;and a mixture of the first- and second-chamber infusions has a potassium concentration of 16 mEq/L or more as measured upon communicably opening the ...

SELF-VENTING CANNULA ASSEMBLY

The present disclosure relates to a self-venting cannula assembly. The self-venting cannula assembly including an outer tube that defines a throughbore, an inner tube, a vent aperture, and a filter element. The inner tube is positioned within the outer tube, which defines a vent channel therebetween. The vent aperture is formed in the outer tube to provide fluid communication between the vent channel and an external environment. The filter element is positioned over the vent aperture and prevents particles having a dimension greater than about 0.2 microns from passing therethrough. 112-. (canceled)13. A self-venting cannula assembly comprising:an outer tube defining a longitudinal axis and having an outer surface and an inner surface;an inner tube positioned within the outer tube, the inner tube and the inner surface of the outer tube defining a vent channel;a vent aperture formed in the outer tube to provide fluid communication between the vent channel and an external environment; anda filter element positioned on the outer surface of the outer tube and over the vent aperture, the filter element being configured to prevent particles having a dimension greater than about 0.2 microns from passing through the filter element.14. The self-venting cannula assembly according to claim 13 , wherein an inner diameter of the outer tube is larger than an outer diameter of the inner tube such that the vent channel is annular.15. The self-venting cannula assembly according to claim 13 , further including a hub portion having a proximal portion with an open proximal end and a distal portion claim 13 , the distal portion secured to a proximal end of the outer tube claim 13 , the hub portion being adapted to engage a medical injection device.16. The self-venting cannula assembly according to claim 15 , wherein the open proximal end of hub portion includes a luer-type connector.17. The self-venting cannula assembly according to claim 15 , wherein the outer tube and the hub portion ...

Mixing/Administration Syringe Devices, Protective Packaging and Methods of Protecting Syringe Handlers

Medicant mixing/administration systems are provided that can include: a medicant vial; a syringe assembly comprising a barrel and a piston; a protective material supporting the syringe assembly and medicant vial; and a member within the system, the member separating the piston of the syringe assembly from the medicant vial. Systems are provided that can include: a syringe assembly comprising a barrel and a piston; having a forward end and an opposing back end; a protective material supporting the syringe assembly; and a needle housing coupled to the protective material. Medicant mixing/administration methods are also provided that can include, within a package, sufficiently clearing a restraining member from between a medicant vial and syringe plunger to pierce the medicant vial with a piercing structure coupled to the syringe plunger, the piercing providing medicant from the vial to the syringe assembly. Additional methods can include, upon opening a package containing a syringe assembly, extending a needle housing from the package. 1. A medicant mixing/administration system comprising:a medicant vial;a syringe assembly comprising a barrel and a piston;a protective material supporting the syringe assembly and medicant vial; anda member within the system, the member separating the piston of the syringe assembly from the medicant vial.2. The system of wherein the protective material is a tray configured to support both the syringe assembly and the medicant vial.3. The system of wherein the member is coupled to the tray.4. The system of wherein the tray is molded and the member is molded as part of the tray.5. The system of wherein the syringe piston is configured to couple to the medicant vial.6. The system of wherein the syringe piston comprises a medicant vial housing extending from an end of the piston claim 5 , the vial housing defining a chamber configured to receive a medicant vial.7. The system of further comprising a vial-piercing device coupled to the ...

INTEGRATED PUNCTURE NEEDLE ADAPTER

The integrated puncture needle adapter is equipped with: a puncture needle; a needle hub; a tubular fixing part for fixing the needle hub; a tubular puncture needle accommodating part provided on a distal side of the tubular fixing part and having therein an accommodating space for accommodating the puncture needle; a second connecting part provided on a distal side of the puncture needle accommodating part; and a separable part which is formed between the tubular fixing part and the puncture needle accommodating part. A part on the distal side of the separable part is separable from a part on the proximal side of the separable part. The puncture needle is exposed when separated. 1. An integrated puncture needle adapter for connecting a drug storage container having a drug storage space to store a drug and a liquid storage container having a liquid storage space to store a liquid for dissolving or diluting the drug , the integrated puncture needle adapter comprising:a puncture needle having a needle tip capable of puncturing a living body at a distal end of the puncture needle and an internal passage opening at both ends of the puncture needle;a needle hub which supports the puncture needle so that the needle tip of the puncture needle protrudes from a distal side of the needle hub;a first connecting part which is provided on a proximal side of the needle hub, and which connects the liquid storage space and the internal passage in a liquid-tight manner by a connection with the liquid storage container;a tubular fixing part which is provided on the distal side of the needle hub, and which fixes the needle hub;a tubular puncture needle accommodating part which is provided on a distal side of the tubular fixing part integrally with the tubular fixing part, and wherein the tubular puncture needle accommodating part has therein an accommodating space for accommodating the puncture needle;a second connecting part which is provided on a distal side of the puncture needle ...

DEVICES USING MEMBRANE MEDIATED FORWARD OSMOSIS

A drug reconstitution device, method of manufacturing the drug reconstitution device and method of producing a reconstituted drug solution using the drug reconstitution device utilizes a forward osmosis membrane element positioned within a housing of the device between an input chamber and an output chamber to draw liquid from the input chamber to the output chamber via an osmotic process. The output chamber contains draw solutes and a drug to be reconstituted to produce the reconstituted drug solution in the output chamber. 1. A drug reconstitution device comprising:a housing having an input chamber and an output chamber, the housing including an inlet connected to the input chamber and an outlet connected to the output chamber;draw solutes in the output chamber of the housing;a drug to be reconstituted in the output chamber of the housing;a forward osmosis membrane element positioned within the housing between the input chamber and the output chamber, the forward osmosis membrane element being configured to draw input water in the input chamber into the output chamber containing the draw solutes and the drug via an osmotic process to produce a reconstituted drug solution in the output chamber of the housing, the reconstituted drug solution in the output chamber being accessible via the outlet to be administered to a patient.2. The drug reconstitution device of claim 1 , wherein the drug to be reconstituted in the output chamber of the housing is in power form.3. The drug reconstitution device of claim 1 , wherein the draw solutes in the output chamber of the housing include a substance selected from one of a salt family and a sucrose family.4. The drug reconstitution device of claim 1 , wherein the forward osmosis membrane element includes a layer of purifying additives on a major surface of the forward osmosis membrane element.5. The drug reconstitution device of claim 4 , wherein the forward osmosis membrane element include an asymmetric forward osmosis membrane ...

Medical Vial Access Device with Pressure Equalization and Closed Drug Transfer System and Method Utilizing Same

A vial access device includes a housing having first and second connectors. The first connector is configured to be secured to a first container and the second connector is configured to be secured to a second container. The vial access device further includes a spike member extending from the housing and having a proximal end and a distal end. The spike member defines a vent lumen and a fluid lumen spaced from the vent lumen with each of the vent lumen and the fluid lumen having a distal opening. A shape defined by a circumference of the spike member is only symmetric about one axis at a position between the proximal end of the spike member and the distal opening of the fluid lumen.

Drug storage container

A drug storage container includes: a first container; a second container that is disposed on the lower end side of the first container; a needle tube for making an internal space of the first container and an internal space of the second container communicate with each other; operating means for performing an operation of bringing the first container closer to the second container; a drug stored in the internal space; and a liquid stored in the internal space. In the drug storage container, with the first container and the second container brought closer to each other by the operating means, the internal space of the first container and the internal space of the second container are made to communicate with each other through the needle tube, and the volume of the internal space of the second container is reduced.

CO-INFUSION APPARATUS

A co-infusion apparatus is provided to prevent foaming of a transfusion when the transfusion is introduced into a medicine container, and to prevent the transfusion from directly hitting a medicine inside a vial. The co-infusion apparatus includes: a container holding section for holding a medicine container and tilting the medicine container; a syringe holding section for holding a syringe, tilting the syringe, and varying an amount of insertion of a plunger of the syringe into a barrel of the syringe: and an insertion operation section for inserting a needle of the syringe through a mouth of the medicine container which is held by the container holding section, and inserting the needle of the syringe through a mixing port of a transfusion bag. 1. A co-infusion apparatus comprising:a container holding section for holding a medicine container and tilting the medicine container;a syringe holding section for holding a syringe, tilting the syringe, and varying an amount of insertion of a plunger of the syringe into a barrel of the syringe; andan insertion operation section for inserting a needle of the syringe through a mouth of the medicine container which is held by the container holding section, and inserting the needle of the syringe through a mixing port of a transfusion bag.2. The co-infusion apparatus according to claim 1 , wherein the container holding section and the syringe holding section are supported by a pivotable support so that pivoting the support causes the container holding section to tilt the medicine container claim 1 , and the syringe holding section to tilt the syringe.3. The co-infusion apparatus according to claim 1 , wherein the syringe holding section is supported by a pivotable support so that pivoting the support causes the syringe holding section to tilt the syringe whereas the container holding section is movable along a curvy route to tilt the medicine container.4. The co-infusion apparatus according to claim 2 , further comprising a ...

SAFETY DRUG HANDLING DEVICE

A drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one syringe adaptor adapted to be attached to a syringe and to the at least one receptacle port adaptor and at least one vial adaptor adapted for connection to a vial containing a drug and adapted for connection to the at least one syringe adaptor, the system being characterized in that at least one of the receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form. 1. A drug mixing system comprising:at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle;at least one vial adaptor adapted for connection to a vial containing a drug; andat least one syringe adaptor adapted to be attached to a syringe and to at least one of said at least one receptacle port adaptor and said at least one vial adaptor, said system being characterized in that at least one of said at least one receptacle port adaptor, said at least one syringe adaptor and said at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of said vial in a liquid, solid or gaseous form.263-. (canceled) The present application is related to and claims priority from the following pending patent applications, the disclosure of which is hereby incorporated by reference:U.S. Provisional Patent Application No. 60/516,613.The present invention relates to drug mixing systems generally.The following U.S. patents and non-U.S. patent publications are believed to represent the current state of the art:U.S. Pat. Nos. 6,221,041; 6,715,520; 6,409,708; PCT US02/40596; WO 2004004806; WO 03086529; WO 9819724; WO 03/086530; WO 0035517 and WO 0211794.The present invention seeks to provide an ...

LIQUID DRUG TRANSFER ASSEMBLY

Liquid drug transfer assemblies for use with a drug vial having a drug vial opening stopped by a drug vial stopper. The liquid drug transfer assemblies include a drug vial stopper puncturing member for puncturing a drug vial stopper. The liquid drug transfer assemblies also include a drug vial adapter having a drug vial adapter skirt, an upright drug vial adapter port and a drug vial adapter sleeve downward depending opposite the upright drug vial adapter port and in flow communication therewith. The drug vial adapter is slidingly disposed on the drug vial stopper puncturing member such that on mounting the liquid drug transfer assembly on the drug vial, the drug vial stopper puncturing member punctures the drug vial stopper to form a throughgoing puncture bore and the drug vial adapter sleeve lines the puncture bore. 1. A liquid drug transfer assembly for use with a drug vial including a drug vial bottle containing a drug component and having a drug vial opening stopped by a drug vial stopper , the liquid drug transfer assembly comprising:(a) a drug vial stopper puncturing member with a drug vial stopper puncturing tip for puncturing the drug vial stopper; and(b) a drug vial adapter having a longitudinal drug vial adapter axis and including a drug vial adapter skirt having a transversely directed drug vial adapter top surface formed with an upright drug vial adapter port, a drug vial adapter body portion for snugly receiving the drug vial opening and a drug vial adapter skirt margin remote from said drug vial adapter top surface, and a drug vial adapter sleeve downward depending from said drug vial adapter top surface opposite said upright drug vial adapter port and in flow communication therewith,said drug vial adapter being slidingly disposed on said drug vial stopper puncturing member such that said drug vial stopper puncturing tip protrudes beyond said drug vial adapter sleeve,the arrangement being such that on mounting the liquid drug transfer assembly on the ...

DOUBLE-ENDED NEEDLE AND MIXING INSTRUMENT

A double-ended needle and a mixing instrument which are capable of suppressing a reverse flow of a solution are provided. A double-ended needle which constitutes part of a mixing instrument includes a first puncture portion and a second puncture portion having inner cavities thereof communicating with each other, an inner cavity of the first puncture portion and an inner cavity of the second puncture portion communicate with each other, and the lateral cross-sectional area of the inner cavity of the first puncture portion is smaller than the lateral cross-sectional area of the inner cavity of the second puncture portion. 1. A double-ended needle used in a mixing instrument configured to mix a first component and a liquid second component , comprising:a first puncture portion capable of sticking into a first container in which the first component is contained; anda second puncture portion capable of sticking into a second container in which the second component is contained;wherein an inner cavity of the first puncture portion and an inner cavity of the second puncture portion are in communication with each other, and the lateral cross-sectional area of the inner cavity of the first puncture portion is smaller than the lateral cross-sectional area of the inner cavity of the second puncture portion.2. The double-ended needle according to claim 1 , whereinan inner cavity of the double-ended needle is reduced gradually from the second puncture portion to the first puncture portion.3122. The double-ended needle according to claim 1 , wherein the ratio (d/d) between an inner diameter dl of a thinnest portion of the inner cavity of the first puncture portion and an inner diameter d of a thickest portion of the inner cavity of the second puncture portion is 0.25 to 0.85.4122. The double-ended needle according to claim 1 , wherein a ratio (d/d) between the inner diameter dl of a thinnest portion of the inner cavity of the first puncture portion and the inner diameter d of a ...

Method for Storing and Delivering a Drug

A container closure delivery system that is suitable for lyophilized pharmaceutical injectable powder products is disclosed. The system comprises storage stable powder formulations and a container closure assembly design wherein the formulation can be filled and lyophilized with a standard fill finish equipment, and the formulations and lyophilization processes are optimized to produce a powder that readily dissolves upon contact with a diluent, thereby facilitating the direct injection of the lyophilized product without the need for a separate reconstitution/mixing/priming step. 1. A delivery device for the administration of a powdered pharmaceutical product comprising:a first component having an ejection port at one end, a chamber holding a reservoir of diluent, and an activating means to facilitate the flow of said diluent through said ejection port;a second component containing a lyophilized drug powder with minimal head space, said second component having an ejection port at one end and capable of engaging said first component at the opposing end, said second component comprising a plunger assembly which upon activation of said first component, allows the diluent ejected from said first component to encounter the powder in said second component, rapidly reconstitute and pass through said ejection port of said second component.2. A device according to wherein said second component is a container closure assembly comprising: a luer lock tab fitting cavity to allow for friction fit of a standard type luer slip syringe;', 'a circular cavity that can accommodate a typical luer lock syringe; and', 'a defined fluid transfer channel which facilitates flow of fluid through said assembled plunger assembly; and, 'a plunger assembly comprising an open end having a chamber capable of holding a liquid active ingredient to be lyophilized and designed to accept said plunger assembly;', 'a locking ridge integrated into the sidewall of said product container;', 'an opposing ...

Connector Device

A connector device for connecting two containers with first and second members slidably displaceable in regard to each other along an axis between a first and a second position is presented. The first member comprises a needle parallel to the axis so that the first container's septum is penetrated by one end of the needle when the first container is introduced into the first member. The second member comprises a coupling to the second container. The other needle end penetrates the second container's septum when the members are in the second position establishing a connection between the two containers. The first member comprises a coupling to the second container coupled to the second member. The first member can couple to the second container when the two members are in the second position and cannot couple to the second container when the two members are in the first position. 1. A connector device for fluidly connecting two containers with two members that are slidably displaceable in regard to each other along an axis between a first and a second position , the connector device comprises:a first member comprising a needle with two ends arranged parallel to the axis in such a way that a septum of the first container is penetrated by one end of the needle when the first container is introduced into a receptacle of the first member;a second member comprising a releasably coupling to a second container wherein the other end of the needle does not come into contact with a septum of the second container coupled to the second member when the members are in the first position, and the other needle end penetrates the septum of the second container when the members are in the second position establishing a fluid connection between the two containers; andwherein the first member comprises a releasably coupling to the second container that is coupled to the second member and wherein the coupling of the first member couples to the second container when the two members are in ...

Cefuroxime safety delivery system

The present invention relates to safety delivery systems for intracameral administration of an appropriate dose of cefuroxime subsequent to cataract and other eye surgery. A preferred embodiment of an cefuroxime safety delivery system according to the invention comprises (a) a perforable sterile vial sterile-filled with a measured amount of cefuroxime, (b) a reconstitution syringe with a male luer fitting sterile-filled with 0.1 ml of isotonic salt solution per mg cefuroxime in the perforable vial and a vial adapter with a female luer fitting or one or more needles with female luer fitting, and (c) one or more sterilized delivery syringes with male luer fitting, each delivery syringe being capable of holding at least 0.1 ml of ejectable liquid and containing a marking indicating a fill volume of 0.1 ml of ejectable liquid. 1. Cefuroxime safety delivery system , comprising(a) A perforable sterile vial sterile-filled with a measured amount of cefuroxime,(b) A receptacle holding 0.1 ml of sterile isotonic salt solution per mg cefuroxime in the perforable vial and means for transferring the isotonic salt solution to the perforable vial and for removing from the perforable vial an aliquot of cefuroxime dissolved in the isotonic salt solution into a delivery syringe, and(c) one or more sterilized delivery syringes with male luer fitting, each delivery syringe being capable of holding at least 0.1 ml of ejectable liquid and containing a marking indicating a fill volume of 0.1 ml of ejectable liquid.2. A cefuroxime safety delivery system according to wherein the receptacle is a sterile-filled reconstitution syringe with a male luer fitting and the means for transferring the isotonic salt solution to the perforable vial and for removing from the perforable vial an aliquot of cefuroxime dissolved in the isotonic salt solution into the delivery syringe is a vial adapter with a female luer fitting or one or more needles with a female luer fitting.3. A cefuroxime safety delivery ...

ASEPTIC CARTRIDGE AND DISPENSER ARRANGEMENT

A cartridge for use with a beneficial agent delivery device having a fillable reservoir. The cartridge includes a reconstitution, unit dose package having first and second compartments, and a fitment. The first compartment contains at least a first constintuent of the beneficial agent. The second compartment contains at least a second constituent of the beneficial agent. The fitment is disposed on the package for interfacing the package to the fillable reservoir. 1. A cartridge for use with a beneficial agent delivery device having a fillable reservoir , said cartridge comprising: a first compartment containing at least a first constintuent of the beneficial agent;', 'at least a second compartment containing at least a second constituent of the beneficial agent; and', 'a fitment disposed on said package for interfacing said package to the fillable reservoir., 'a reconstitution, unit dose package, comprising2. The cartridge of wherein the cartridge is adapted to communicate with a delivery portion of the delivery device that comprises one of a needle claim 1 , a connector and a nozzle.3. (canceled)4. (canceled)5. The cartridge of wherein said first compartment is segregated from said second compartment by a rupturable barrier.6. The cartridge of wherein at least a portion of said package comprises a flexible wall.7. (canceled)8. The cartridge of wherein at least a portion of said flexible wall is preformed to define at least a portion of said first and second compartments.9. The cartridge of wherein at least a portion of said flexible wall comprises a peelable foil layer.10. (canceled)11. The cartridge of further comprising a fluid passageway between said first compartment and said second compartment.12. The cartridge of further comprising a static mixer disposed in said fluid passageway.13. The cartridge of further comprising a fluid passageway between said package and the delivery device claim 1 , and a static mixer disposed in the fluid passageway.14. (canceled)15 ...

BLUNT TIP VIAL ACCESS CANNULA AND METHOD FOR MANUFACTURE

A method of manufacturing a metal cannula is disclosed. The method includes the step of providing a metal cannula having a longitudinal axis and defining a fluid channel. Next, the metal cannula is pressed to substantially close the fluid channel and define a first segment and a second segment. In a next step, the metal cannula is cut to separate the first segment from the second segment of the metal cannula. Each of the first and second segments have a pressed edge. The pressed edge substantially seals the fluid channel and has two pressed corners. Afterwards, each of the pressed corners are cut from the pressed edge of the first segment to define a pair of side openings and a distal blunt edge on the first segment. The side openings are in fluid communication with the fluid channel. 113-. (canceled)14. A method of manufacturing a metal cannula , comprising the steps of:providing a metal cannula having a fluid channel defined therein and defining a longitudinal axis therethrough;cutting a u-shaped notch defining a first segment and a second segment, each of the first and second segments having opposed distal tips;cutting the opposed tips of the first segment and the second segment in an acute angle in relation to a longitudinal axis of the metal cannula;arranging the blunt metal tip in a crimping device; andcrimping the first and second segments to form a blunt metal tip, the blunt metal tip having a substantially closed distal end and defining a pair of side openings.15. The method according to claim 14 , comprising a further step of attaching the proximal end of the blunt metal tip cannula to a hub assembly to form a vial access cannula.16. The method according to claim 15 , wherein the metal cannula is coupled to the distal end of the hub assembly by a fastening technique selected from the group consisting of gluing claim 15 , snap-fitting claim 15 , crimping claim 15 , press-fitting claim 15 , and molding.17. The method according to claim 14 , comprising a ...

DRUG SOLUTION TRANSFER METHOD AND DRUG SOLUTION TRANSFER APPARATUS

A drug solution transfer method includes step S of inserting a needle into a drug solution container through a rubber stopper and sucking drug solution in the drug solution container, step S of checking whether or not a solution collection inlet at a tip of the needle has shifted into the rubber stopper upon extracting the needle from the drug solution container, step S of pulling a plunger of a syringe provided with the needle so that an inside of the needle and an inner space of the syringe have negative pressure, and step S of relatively shifting the needle along with the syringe to be distant from the drug solution container so as to extract the solution collection inlet of the needle from the rubber stopper. 1. A drug solution transfer method comprising:pulling a plunger of a syringe in a state where a needle of the syringe penetrates a rubber stopper of a drug solution container to suck drug solution from the drug solution container into the syringe;relatively shifting the drug solution container and the syringe to be distant from each other and then stopping to locate a solution collection inlet at a tip of the needle inside the rubber stopper;pulling the plunger in a state where the solution collection inlet is located inside the rubber stopper so that an inner space of the syringe has negative pressure; and thenrelatively shifting the drug solution container and the syringe to be distant from each other so as to extract the solution collection inlet of the needle from the rubber stopper.2. The drug solution transfer method according to claim 1 , wherein claim 1 , when locating the solution collection inlet inside the rubber stopper claim 1 , there is a solution collection inlet closing portion of at least 1 mm thick between a lower end of the solution collection inlet and a lower end of the rubber stopper claim 1 , and there is a solution collection inlet closing portion of at least 1 mm thick between an upper end of the solution collection inlet and an ...

Dispense Interface Assembly

The invention is related to an apparatus comprising an inner body of a dispense interface and a manifold, wherein the inner body comprises a recess configured to receive a distal needle from a distal end of the inner body, a first fluid reservoir and a second fluid reservoir, and wherein the manifold comprises a filling block configured to redirect flow, a fluid groove arrangement configured to provide a fluid connection to the filling block, wherein the inner body and the manifold are assembled such that there is formed a channel providing a fluid connection from the first fluid reservoir and the second fluid reservoir, respectively, via the fluid groove arrangement and the filling block to the recess. The invention is further related to a drug delivery device comprising an apparatus of the aforementioned kind 115-. (canceled)17. Apparatus according to claim 16 , wherein the inner body comprises a cavity with a fluid connection to the recess claim 16 , which cavity is arranged on an axis defined by the recess and wherein the filling block comprises a protrusion claim 16 , and wherein the inner body and the manifold are assembled such that the cavity receives the filling block.18. Apparatus according to claim 17 , wherein the protrusion is configured to fill more than half of a volume of the cavity.19. Apparatus according to claim 16 , wherein the inner body comprises at least one outwardly protruding member configured to form an interference fit with an outer body of the dispense interface.20. Apparatus according to claim 16 , wherein the inner body comprises a flat surface and wherein the recess is arranged on a plane of symmetry of the flat surface claim 16 , which plane of symmetry is parallel to a longitudinal axis of the inner body.21. Apparatus according to claim 20 , wherein the first fluid reservoir and the second fluid reservoir are arranged symmetrically with respect to the plane of symmetry of the flat surface.22. Apparatus according to claim 20 , ...

Two-piece vial transfer needle assembly

The present disclosure relates to a vial transfer needle assembly including a first molding member and a second molding member. The first molding member includes a hub portion that has a proximal piercing tip and a distal portion. The hub portion defines a lumen that passes therethrough. The second molding member includes a central housing, a proximal skirt, and a distal skirt. The second molding portion is molded at least partially about the first molding portion to form a monolithic structure. The piercing tip is positioned to extend into a first cavity that is defined by the proximal skirt. The distal portion of the first molding member is positioned to extend through a second cavity that is defined by the skirt. The distal skirt is dimensioned to receive a medical device.

Cylinder-piston unit suitable for storing injection solutions for a needle-free injector and method for the bubble-free automatic or manual filling of the cylinder-piston unit, also under atmospheric pressure

A pressure-stable cylinder/piston unit which blocks water vapor and oxygen and is designed for a needle-free injector, with a chamber arranged in a cylinder, which blocks water vapor and oxygen, and designed for long-term and sterile storage of an injection solution, an end wall with at least one nozzle bore or one outlet element, a pressure-stable outer cylinder, and a pressure-stable piston arranged movably in the chamber and blocking water vapor and oxygen. Methods for bubble-free, automatic or manual filling of the cylinder/piston unit, also at atmospheric pressure are also disclosed.

Fluid Container Devices, Methods and Systems

A drug container assembly for use with a parenteral drug delivery device is disclosed. The container assembly includes a container configured to hold the medication and an intermediate port connector. The port connector may be fixedly coupled to the container and removably coupled to the delivery device in a convenient, reliable, and sealed manner In use, the port connector may convey the medication from the container to the delivery device for delivery to the patient. 1. A delivery port for use with a delivery device , the delivery port comprising:an inlet;an outlet;a pin;a first O-ring; anda second O-ring, wherein the port connector having a sealed configuration in which the first and second O-rings are positioned in sealed engagement with the pin to close the delivery port; an intermediate configuration in which the first O-ring is positioned in sealed engagement with the delivery device and the second O-ring is positioned in sealed engagement with the pin; and a delivery configuration in which the first O-ring is positioned in sealed engagement with the delivery device and the delivery port is positioned in fluid communication with a fluid passageway of the delivery device.2. The delivery port of claim 1 , wherein in the delivery configuration claim 1 , the first and second seals are positioned in sealed engagement with the delivery device.3. The delivery port of claim 1 , wherein in the delivery configuration claim 1 , the first seal is positioned in sealed engagement with the delivery device and the second seal is positioned in sealed engagement with the pin.4. The delivery port of claim 1 , wherein the port connector includes a shoulder that transfers movement of the port connector to the first O-ring.5. The delivery port of claim 4 , wherein the first and second O-rings are positioned on a same side of the shoulder.6. The delivery port of claim 4 , wherein the first O-ring is positioned below the shoulder and the second O-ring is positioned above the ...

FILLING APPARATUS FOR DRUG CONTAINERS AND METHOD FOR FILLING THE SAME

An apparatus for filling drug containers such as syringes, and related filling methods, are disclosed. The apparatus uses a removable pumping syringe mounted to the apparatus and located intermediate between the bulk source of drug and the container (e.g. syringe) to be filled such that the drug is first pumped into the pumping syringe and then pumped into the container (e.g. syringe). Actuation of the intermediate pumping syringe is effected with a linear actuator such as a step motor which is engaged to the plunger of the pumping syringe. The linear actuator is controlled by a controller which typically allows different filling and calibrating procedures. 1) A filling apparatus for filling a container with a liquid , the apparatus comprising:a) a base structure, the base structure comprising a supporting structure configured to releasably support at least one barrel of at least one pumping syringe;b) an actuating member slidingly mounted to the base structure, the actuating member being configured to releasably engage at least one plunger of the at least one pumping syringe;c) a linear actuator fixedly mounted to the base structure and drivingly connected to the actuating member for linearly displacing the actuating member;d) a controller operatively connected to the linear actuator for controlling the linear actuator according to a predetermined program.2) A filling apparatus as claimed in claim 1 , further comprising a receiving structure mounted to the base structure and configured to releasably support connecting tubing.3) A filling apparatus as claimed in claim 2 , wherein the connecting tubing further comprises a dual check valve configured to be fluidly connected to the at least one pumping syringe claim 2 , and a container connector configured to be fluidly connected to the container.4) A filling apparatus as claimed in any of to claim 2 , wherein the base structure comprises a housing claim 2 , and wherein the supporting structure comprises at least one ...

Pressure-regulating vial adaptors

In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. The regulator assembly can include a valve configured to transition between a closed configuration and an opened configuration.

Vented Needle

A vented needle comprises a distal end configured to pierce a seal of a first container having a top and a bottom surface and a seal of a second container having a top and a bottom surface. An interior lumen is configured to fluidly couple the first container and a fluid transfer device and the second container and the fluid transfer device. A middle portion is configured to engage the seals of the first container and the second container and having one or more axially extending vents. At least one of the one or more vents is configured to extend axially past the top and bottom surfaces of the seal of the first container and configured to fluidly couple the first container and ambient air outside the first container. None of the one or more vents are configured to extend axially past top and bottom surfaces of the seal of the second container. 1. A needle comprising:a distal end configured to pierce a seal of a first container having a top and a bottom surface and a seal of a second container having a top and a bottom surface;an interior lumen configured to fluidly couple the first container and a fluid transfer device and the second container and the fluid transfer device; anda middle portion configured to engage the seals of the first container and the second container and having one or more axially extending vents, at least one of the one or more vents being configured to extend axially past the top and bottom surfaces of the seal of the first container and configured to fluidly couple the first container and ambient air outside the first container, none of the one or more vents being configured to extend axially past top and bottom surfaces of the seal of the second container.2. The needle of claim 1 , wherein the one or more vents are formed by a coating on an outer surface of the needle.3. The needle of claim 2 , wherein the coating forms one or more grooves.4. The needle of claim 2 , wherein the coating is comprised of an air permeable material.5. The needle ...

FLEXIBLE PACKAGE WITH A SEALED STERILE CHAMBER FOR THE RECONSITUTION AND ADMINISTRATION OF FLUID MEDICINAL OR NUTRITIONAL SUBSTANCES INSTILLABLE INTO THE BODY OF A PATIENT

A package for infusion or instillation of medicinal or nutritional products into the body of a patient comprises a bag of liquid diluent equipped with at least one drain tube and a mixing tube equipped with a coupling and perforation device for a bottle of a pharmacological or nutritional substance in powder, gel or other material, provided with a perforatable cap. The package comprises a flexible airtight sterile casing, containing said bottle of the substance in powder or other and the coupling and perforation device. The bottle is housed in the casing in a coupling position with the coupling and perforation device and is manually manoeuvrable from the outside of the casing up to a perforating position of the cap of the bottle. 1. A package for infusion or instillation of medicinal or nutritional products into the body of a patient , comprising a bag of liquid diluent equipped with at least one drain tube provided with a closing device , and a mixing tube equipped with an openable closure and which ends with a coupling and perforation device for a bottle of a pharmacological or nutritional substance in powder , gel or other material , provided with a perforatable cap , said package comprising at least a flexible airtight sterile casing , containing said bottle of the substance in powder or other and said coupling and perforation device , said bottle being housed in the casing in a coupling position only with the coupling and perforation device and being manually manoeuvrable from the outside of the casing up to a perforating position of said cap through the same coupling and perforation device , wherein said coupling and perforation device comprises a first element slidably coupled with a second element and movable between said coupling position of the bottle and said perforating position of the cap of the bottle , in which said first element comprises a ring from which at least two flaps equipped with notches suitable to accommodate the bottle in the coupling ...

Adaptor for Coupling with a Medical Container

The invention relates to an adaptor for coupling with a medical container closed by a septum, the adaptor comprising:—a gripping member () for securing the adaptor to the medical container,—a needle access port intended to face an outer surface of the septum,—a pierceable elastomeric piece () having a longitudinal axis located into the needle access port, said pierceable elastomeric piece having a recess () with a proximal opening and an outer wall () in contact with the needle access port,—attaching means for maintaining the elastomeric piece into the needle access port. The invention also relates to an assembly comprising such an adaptor and a medical container, and to the use of such an adaptor for preventing the contamination inside a medical container closed by a septum. 1. An adaptor for coupling with a medical container , said medical container having a collar closed by a septum , said septum having an outer surface directed towards the outside of the medical container , the adaptor comprising:a gripping member for securing the adaptor to the medical container,a needle access port facing the outer surface of the septum when the adaptor is coupled to the medical container, anda pierceable elastomeric piece having a longitudinal axis located into the needle access port, said pierceable elastomeric piece having a recess with a proximal opening, an outer wall in contact with the needle access port, and a distal surface comprising a protruding part engageable with the outer surface of the medical container septum,wherein the elastomeric piece and the needle access port comprise an attaching arrangement for maintaining the elastomeric piece into said needle access port when a pressure is applied by the protruding part on the outer surface of the septum.2. The adaptor according to claim 1 , wherein a ratio between a height of said recess and a width of said recess ranges from 0.3 to 0.7.3. The adaptor according to claim 1 , wherein said recess comprises a bottom ...

CONTAINER AND KIT FOR PROVIDING PARENTERAL NUTRITION

The invention relates to a container (), preferably a bag (), for providing parenteral nutrition, said bag having an interior that is sub-divided into separate compartments () and said compartments () being used to hold liquids for parenteral feeding. The container is designed and further developed with regard to administering parenteral nutrition according to the individual metabolism of a patient and with regard to simplicity of use, such that at least two compartments () are formed in the interior and a liquid connection can be produced between said compartments. Also disclosed is a kit for providing parenteral nutrition. 114-. (canceled)1526123456789123456789123456789123456789. A container () for the provision of parenteral nutrition , the container comprising an inner compartment subdivided into separate chambers ( , , , , , , , , ) , wherein the chambers ( , , , , , , , , ) serve the purpose of accommodating liquids for parenteral nutrition , wherein at least two chambers ( , , , , , , , , ) are constructed in the inner compartment , and wherein it is possible to produce a fluid connection between the at least two chambers ( , , , , , , , , ).16123456789. A container according to claim 15 , wherein the fluid connection between the chambers ( claim 15 , claim 15 , claim 15 , claim 15 , claim 15 , claim 15 , claim 15 , claim 15 , ) can be regulated.1712345678930. A container according to claim 15 , wherein the chambers ( claim 15 , claim 15 , claim 15 , claim 15 , claim 15 , claim 15 , claim 15 , claim 15 , ) are configured to be opened outwardly via a valve () claim 15 , and to be emptied to the outside at least one of entirely claim 15 , partially claim 15 , or in a dosed manner.18. A container according to claim 15 , wherein:{'b': '1', 'at least one first chamber () contains a parenteral nutrition system with a first amount of energy;'}{'b': '2', 'at least one second chamber () contains a liquid used to cover fluid requirements, with a second amount of energy ...

TRANSFER SET

A transfer set generally includes an outer sleeve configured for connecting an inner sleeve to a vial such that a passage of the inner sleeve is disposed above a stopper of the vial. The transfer set further includes a cap configured for insertion into the outer sleeve such that the cap is connected to the outer sleeve and is detachable from the outer sleeve via rotation of the cap relative to the outer sleeve. The cap has an interior space and a cam disposed within the interior space, wherein the inner sleeve, and a spike within the inner sleeve, extend into the interior space when the cap is connected to the outer sleeve, and wherein, as the cap rotates relative to the outer sleeve for detachment of the cap from the outer sleeve, the cam interacts with the follower to translate the spike toward the stopper for puncturing the stopper. 1. A transfer set for transferring liquid into or out of a vial sealed by a stopper , the transfer set comprising:an inner sleeve comprising a passage extending through the inner sleeve along a longitudinal axis;an outer sleeve configured for connecting the inner sleeve to the vial such that the passage is disposed above the stopper of the vial;a spike comprising a follower, wherein the spike is disposed within the passage of the inner sleeve and is configured for longitudinal translation along the passage to puncture the stopper; and a closed top wall;', 'an annular side wall extending from the closed top wall to define an open bottom and an interior space of the cap; and', 'a cam disposed within the interior space,, 'a cap configured for insertion into the outer sleeve such that the cap is connected to the outer sleeve and is detachable from the outer sleeve via rotation of the cap relative to the outer sleeve, the cap comprisingwherein the inner sleeve and the spike extend into the interior space when the cap is connected to the outer sleeve, andwherein, as the cap is rotated relative to the outer sleeve for detachment of the cap ...

Apparatus for Transferring a Liquid Between a Storage Container and At Least One Further Use Container

An apparatus for transferring a liquid between a storage container and at least one further use container has a storage-container sealing portion for leaktight abutment of a main body of the transfer apparatus against the storage container. A hollow-needle assembly has a hollow needle. The hollow-needle assembly can be displaced in a linear manner along a movement axis relative to the main body by means of a gear mechanism between a retracted rest position and an extended connecting position. In the latter, the hollow needle creates a liquid connecting duct between the storage container and the transfer apparatus. A connecting portion serves to connect the transfer apparatus to the use container in a leaktight manner. A rotary-actuation element is operatively connected to the hollow-needle assembly via the gear mechanism. The gear mechanism has a driver ring that is mounted in the main body axially and so as to be rotatable about the movement axis. Said driver ring interacts with a complementary thread of the hollow-needle assembly for the displacement thereof. The driver ring is connected to the rotary-actuation element for conjoint rotation during the displacement. This results in a transfer apparatus having improved operational reliability, in particular when used by inexperienced patients. 1. An apparatus for transferring a liquid between a storage container and at least one further use container ,having a storage-container sealing portion for leaktight abutment of a main body of the transfer apparatus against the storage container; a retracted rest position and', 'an extended connecting position in which the hollow needle creates a liquid connecting duct between the storage container and the transfer apparatus,, 'having a hollow-needle assembly with a hollow needle, wherein the hollow-needle assembly is displaceable in a linear manner along a movement axis relative to the main body by means of a gear mechanism between'}having a connecting portion for connecting ...

PERFORATING NEEDLE FOR FLASK WITH SEPTUM

A perforating needle intended to be inserted into a flask through a stopper or septum to inject and remove a fluid includes a pointed end for piercing the stopper and a cylindrical body. The central body includes a central channel through which the fluid may enter and leave the flask and a side wall having at least one lateral orifice. The orifice is in fluid communication with the central channel. A lower end of the orifice is, in use, essentially level with an inner face of the stopper. The orifice is extended toward the pointed end by at least one slot, a shape of which is essentially tangential to a flow of the fluid so as to channel the fluid along an axis of the needle. The side wall includes at least two diametrically opposite lateral orifices arranged on either side of a central island. 1. A perforating needle intended to be inserted into a flask through a stopper or septum to inject and remove a fluid , the needle comprising:a pointed end configured to pierce the stopper; anda cylindrical body comprising a central channel through which the fluid may enter and leave the flask and a side wall comprising at least one lateral orifice, the orifice being in fluid communication with the central channel and a lower end of the orifice being, in use, essentially level with an inner face of the stopper, the orifice being extended toward the pointed end by at least one slot, a shape of which is essentially tangential to a flow of the fluid so as to channel the fluid along an axis of the needle,wherein the side wall comprises at least two diametrically opposite lateral orifices arranged on either side of a central island, the central island having a separating rim forming an angle of between 15° and 60°,wherein the separating rim penetrates the central channel, andwherein the slots extending the orifices emerge near the pointed end.2. (canceled)3. The perforating needle according to claim 1 , wherein the perforating needle is comprised of rigid plastic material.4. The ...

PRESSURE-REGULATING VIAL ADAPTORS

A vial adaptor can include a connector interface and/or a piercing member. The vial adaptor can include a regulator assembly. The regulator assembly can include a regulator base, a regulator nest coupled with the regulator base, and/or a storage chamber formed at least partially by one or both of the regulator base and regulator nest. The regulator assembly can include a cover connected to one or both of the regulator base and regulator nest and fitted around a radially outward portion of one or both of the regulator base and regulator nest. In some cases, the regular assembly includes a flexible enclosure connected to the regulator nest and configured to transition between a contracted configuration and an expanded configuration. In some cases, the flexible enclosure is inhibited from transitioning to the expanded configuration prior to removal or modification of the cover from the regulator assembly. 1. A pressure-regulating vial adaptor comprising:a connector interface;a piercing member in communication with the connector interface; and a storage chamber;', 'a flexible enclosure positioned within the storage chamber in a contracted configuration and configured to expand in an expanded configuration;', 'an expansion inhibitor connected to a portion of the regulator assembly, the expansion inhibitor comprising one or more weakened portions configured to facilitate a tear in the expansion inhibitor when the flexible enclosure moves from the contracted configuration to the expanded configuration., 'a regulator assembly comprising2. The vial adaptor of claim 1 , wherein at least one of the one or more weakened portions is a perforation.3. The vial adaptor of claim 1 , wherein the expansion inhibitor extends over at least a portion of a side of the regulator assembly.4. The vial adaptor of any of claim 1 , wherein the expansion inhibitor includes an aperture when the flexible enclosure is in the contracted configuration.527.-. (canceled)28. A method of manufacturing a ...

CONNECTOR SECTION

A locking element for a connector configured to connect two components of a fluid transfer system and a connector that comprises the locking element are described. The connector comprising the locking element is configured to provide continuous fluid channels between a first component and a second component of a fluid transfer system, the fluid is a hazardous drug and the connector is designated for safe and contamination-free transfer of said hazardous drug from first to second container while isolating the needle tips and causing no dangerous and harmful leaks. 1. A locking element for a connector configured to connect two components of a fluid transfer system , the locking element comprising:a. a body comprising an upper part having a hollow interior and a lower part having a channel passing through it;b. elongated flexible arms having distal enlarged elements attached to the sides of the upper part of the body and projecting downwards parallel to the sides of lower part of the body; andc. an insert configured to be inserted into the channel, wherein the insert is made of flexible material and comprises at least one bore passing through it which forms a sleeve through which at least one hollow needle is able to pass;characterized in that the locking element comprises a rigid flat plastic annular disc at the free end of the lower part of the body.2. The locking element of claim 1 , comprising two bores through the insert.3. A connector configured to connect two components of a fluid transfer system claim 1 , the connector comprising:a. a hollow cylindrical body that has a closed upper end comprising an exterior side and an interior side, the upper end comprising a connection arrangement on the exterior side and a needle holder on the interior side, the connector section configured to connect to a first component of a fluid transfer system;{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'b. a locking element according to , wherein the body of the locking element ...

METHOD AND APPARATUS FOR APPLYING A TOPICAL SOLUTION

An applicator for dispensing a solution having two or more components includes a hollow body having a head provided at one end of the hollow body for dispersion of the solution and a breaking mechanism attached to the hollow body. The breaking mechanism includes at least one projection extendable into an interior of the hollow body. The applicator further includes a plurality of ampoules placed in the interior of the hollow body. The plurality of ampoules contains the two or more components. Upon activation of the breaking mechanism, the at least one projection applies a force to the plurality of ampoules such that the plurality of ampoules break and release the two or more components to form the solution. 1. A method for storing , mixing , and applying a solution having a first component and a second component which inhibits exposure of the first and second components to air and moisture until just prior to application , said method comprising:hermetically sealing the first component within a first at least one ampoule;hermetically sealing the second component within a second at least one ampoule;disposing the first at least one ampoule and the second at least one ampoule within a hollow body having a head for dispersion of the solution and a breaking mechanism having a projection extendable into an interior of the hollow body;activating the breaking mechanism such that the projection applies a force to break the first at least one ampoule and the second at least one ampoule and release the first and second components from the first at least one ampoule and the second at least one ampoule; andtopically applying the solution having the first and second components through the head.2. The method of claim 1 , wherein the first at least one ampoule comprises two ampoules and the second at least one ampoule comprises two ampoules.3. A method for storing claim 1 , mixing claim 1 , and applying a solution having a first component and a second component which inhibits ...

MIXING PEN NEEDLE

An injection device is provided with dual medicament chambers and a mixing pen needle assembly, whereby predetermined dosages of two medicaments can be provided to a mixing reservoir in the pen needle assembly and delivered simultaneously with the injection device. 1. A medication pen comprising:a pen body having a distal end and a proximal end, and having a first medication compartment and a second medication compartment;first and second dosing mechanisms and first and second dosage plungers engaged in the respective first and second medication compartments;a movable housing received on the distal end of the pen body adapted to be received in first and second positions on the pen body;a pen needle assembly received on the distal end of the movable housing, said pen needle assembly comprising a patient end needle, a filler needle, and a collapsible mixing reservoir intermediate and accessed by said patient end needle and said filler needle;wherein the movable housing is movable between a first position in which the filler needle is in fluid communication with the first medication compartment and a second position in which the filler needle is in fluid communication with the second medication compartment; andwherein collapsing the mixing reservoir forces medication in the mixing reservoir through the patient end needle during an injection.2. The medication pen according to claim 1 , wherein each medication compartment comprises a medication cartridge and each dosage plunger engages a respective medication cartridge.3. The medication pen according to claim 1 , further comprising a check valve on the filler needle preventing backflow from the mixing reservoir into the first and second medication compartments.4. The medication pen according to claim 1 , wherein the first and second dosing mechanisms comprise first and second rotatable knobs protruding from the proximal end of the pen body.5. The medication pen according to claim 1 , wherein the movable housing is ...

METHOD AND APPARATUS FOR INJECTING A NEUROTOXIN INTO A LOCALIZED AREA

A syringe assembly for administration of a neurotoxin, the syringe assembly comprising: a syringe comprising: a clear syringe barrel with dosage markings completely encircling the clear syringe barrel; and a plunger having a plunger body and a clear inverted plunger tip; and a needle assembly comprising a needle and a sealing hub for removably attaching the needle assembly to the syringe, wherein the needle is approximately 0.15 inches to approximately 0.3 inches in length and has a gauge of approximately 27 gauge to approximately 35 gauge. 110.-. (canceled)11. A method for injecting a neurotoxin into a body of a patient , the method comprising: [ a clear syringe barrel with dosage markings completely encircling the clear syringe barrel; and', 'a plunger having a plunger body and a clear inverted plunger tip; and, 'a syringe comprising, 'a needle assembly comprising a needle and a sealing hub for removably attaching the needle assembly to the syringe;, 'providing a syringe assembly comprisingattaching a first needle assembly to the syringe assembly;passing the needle into a container of neurotoxin and drawing the neurotoxin into the syringe assembly;removing the first needle assembly from the syringe assembly;attaching a second needle assembly to the syringe assembly, wherein the needle of the second needle assembly is shorter and narrower than the needle of the first needle assembly; anddelivering the neurotoxin into the body of a patient.12. The method according to wherein the syringe is a 1.0 cc syringe.13. The method according to wherein the dosage markings are cc markings.14. The method according to wherein the dosage markings are unit markings.15. The method according to wherein the plunger body is clear.16. The method according to wherein the plunger body is opaque.17. The method according to wherein the needle is 0.25 inches in length.18. The method according to wherein the needle is 33 gauge.19. The method according to wherein a marker is disposed between ...

PREPARATION OF THERAPEUTIC FOAM

A device is described for facilitating the preparation of therapeutic foam e.g. for the treatment of varicose veins. A pressurised vial contains a sclerosant liquid, e.g., polidocanol solution, and a sterile gas which is readily absorbed by the body, e.g., carbon dioxide, oxygen or a mixture of these gases. The vial is provided either with a specialised stopper/seal into which a syringe nozzle may be inserted or alternatively a septum seal which may be penetrated by a hypodermic needle. The quantities of gas and liquid and the pressure in the vial are pre-set so that, on connection of a syringe to the vial, a predetermined volume of both gas and liquid is transferred to the syringe, with the intention that the syringe is then used to make a foam by known means. The use of the vial ensures that the ratio of gas to liquid in the foam is standardised, and also provides a convenient way of packaging the gas and liquid and of filling the syringe in a sterile manner. 1. A vessel having sterile contents , a first phase comprising a foamable sclerosant liquid solution, and', 'a second phase in contact with the first phase comprising a gas mixture consisting essentially of oxygen and carbon dioxide pressurized at a pressure above atmospheric pressure,', 'the vessel having a resilient closure, which is pierceable by a hollow hypodermic needle, and which forms a seal around the needle when it is pierced, and', 'wherein the vessel is configured for transfer of the sterile contents from the vessel to the syringe through the hypodermic needle inserted through the resilient, pierceable closure and into the foamable sclerosant liquid solution,', 'wherein the pressure of the gas mixture in the vessel is selected such that, upon piercing of the resilient closure by the hollow hypodermic needle and passage of the needle into the foamable liquid the pressurized gas mixture forces a volume of the foamable sclerosant liquid solution into the syringe, followed by the passage of a volume ...

Bodily fluid drainage assembly

A bodily fluid drainage assembly can include a fluid bag and one or more covers. The assembly can include one or more volume indicators from which an approximate volume of a bodily fluid that is retained within can be ascertained. In some arrangements, a cover includes a volume indicator that defines an opening through which a transparent or semitransparent portion of the bag can be viewed.

Pill Administration Device with Liquid Reservoir

A pill administration device has a collapsible reservoir that can contain liquid and a pill receptacle that is coupled to the reservoir and can store one or more pills, with two rupturable membranes keeping the pill(s) isolated from the liquid and trapped in the pill receptacle. By collapsing the reservoir containing the liquid, a user can break the membranes and propel the liquid and pill(s) into his or her mouth to be swallowed. 1. A pill administration device , comprising:a collapsible reservoir for containing a liquid, the reservoir being formed by a container; anda pill receptacle for containing one or more pills; the pill receptacle is coupled to the reservoir in sealed fluid communication therewith;', 'the pill receptacle is isolated from the reservoir by a first rupturable fluid impermeable membrane; and', 'the pill receptacle has a receptacle opening remote from the reservoir and from the first membrane for inserting and discharging pills; and, 'whereina first cap having a pill expulsion passage defined therethrough;a second rupturable membrane extending across the pill expulsion passage to close the pill expulsion passage;the first cap being securable over the pill receptacle to trap one or more pills in the pill receptacle between the first and second membranes;wherein, in operation, collapsing the reservoir drives liquid contained therein to rupture the first and second membranes and travel through the pill expulsion passage to exit the pill administration device.2. The pill administration device of claim 1 , wherein the pill receptacle is formed by the container.3. The pill administration device of claim 2 , wherein:a quantity of liquid is disposed in the reservoir; andthe first membrane is sealingly secured directly to the container.4. The pill administration device of claim 3 , wherein:the container has an open end;the pill receptacle is disposed between the first membrane and the open end of the container; andthe first cap is securable to the open ...

TRANSFER DEVICE FOR MEDIA, COMPRISING A NON-RELEASABLY LOCKABLE ADAPTER

A transfer device () for removing or transferring a medium out of or into a bottle () having a bottle neck () that can be closed by means of a closure (), including a first adapter part (), which can be positioned on the bottle, and a second adapter part (), which interacts with the first adapter part, which can be displaced in the longitudinal direction of the bottle, and has a conducting element () for piercing the closure. After the second adapter part () has been displaced along the first adapter part in the direction of the closure () and the second adapter part has been locked, the first adapter part () is non-releasably fastened to or around the bottle (). 139.-. (canceled)4010100200400203442. A transfer device ( , , , ) for the withdrawal or delivery of a medium out of or into a bottle () with a neck () , that is sealable by a closure () , comprising:{'b': 12', '112', '212', '412, 'a first adapter component (, , , ) that can be positioned on the bottle, and'}{'b': 14', '114', '214', '414', '50, 'a second adapter component (, , , ), which interacts with the first adapter component, is moveable in the longitudinal direction of the bottle, and comprises a delivery element () for piercing the closure,'}{'b': 14', '114', '214', '414', '12', '112', '212', '412', '42', '20, 'wherein, after moving the second adapter component (, , , ) along the first adapter component (, , , ) in the direction of the closure () and locking of the second adapter component, the first adapter component is secured in position non-detachably at the bottle () or around the bottle,'}{'b': 10', '100', '200', '400', '20', '12', '112', '212', '412', '14', '114', '214', '414', '42, 'wherein the transfer device (, , , ) is secured in position at or around the bottle (), the first and the second adapter components (, , , ; , , , ) form an enclosed sealed envelope that surrounds the bottle at least in the area of the closure element (),'}{'b': 14', '214', '44', '46', '50, "the second adapter ...

CONNECTOR FOR A CONTAINER INCLUDING A MEDICINAL ACTIVE INGREDIENT

The invention relates to a connector for containers containing medicinal active ingredient, which connector makes it possible to transfer active ingredient from one container into another container. 1. A connector for containers containing medicinal active ingredient , comprising: a guide element having a duct designed for transferring a medicinal active ingredient and having first and second ends;', 'a piercing element arranged, at least in certain sections, in the duct and axially moveably guided within the duct by the guide element; the piercing element having first and second ends, the second end including a stop, and', 'a partition wall located proximate the first end of the guide element;', 'wherein, by connecting the first container in the first connection region, the piercing element can be moved from a starting position, in which the piercing element does not open the partition wall, into an end position, in which the first end of the piercing element opens the partition wall in order to transfer a medicinal active ingredient, and wherein the stop on the second end of the piercing element engages with the second end of the guide element to limit further movement of the piercing element., 'a first connection region for the connection of a first container, the first connection region including2. The connector as claimed in claim 1 , wherein the first end of the piercing element is sharpened or pointed and wherein the stop on the second end of the piercing element is in the form of a collar.3. The connector as claimed in claim 1 , wherein the piercing element projects by its first end facing the first connection region beyond the guide element.4. The connector as claims in claim 1 , wherein the piercing element and the guide element are designed in such a way that a clearance for transferring a medicinal active ingredient remains between an outer face of the piercing element and an inner face claim 1 , forming the duct claim 1 , or the guide element.5. The ...

Syringe With Connector

A syringe comprising a syringe barrel having a distal end, a distal tip, a proximal end, a barrel sidewall extending between the distal end to the proximal end and defining a chamber, the barrel sidewall having a barrel sidewall thickness t, the distal end of the syringe barrel including a distal wall is disclosed. The syringe includes a connector extending from the syringe barrel including a collar disposed coaxially around an elongate tip in fluid communication with the barrel to form a channel between the elongate tip and the collar, including an inside surface, an outside surface and a plurality of ribs extending radially outwardly from the outside surface and separated by spaces, each of the plurality of ribs having a height H and a width W, wherein there is a ratio of the height H to the barrel sidewall thickness tin a range of 0.75 and 1.

MEDICAL BAG

A medical bag comprising: a bag main body comprising a flexible sheet material having an interior portion partitioned via a partition part into a first space and a second space that is smaller than the first space, a first liquid housed in the first space, and a second liquid housed in the second space. When the volume of the first liquid is set as L and the volume of the second liquid is set as L, L/L is 2.0 to 6.0. The partition part has a breaking strength of 5 to 25 kPa. 1. A medical bag comprising:a bag main body comprising a flexible sheet material having an interior portion partitioned via a partition part into a first space and a second space that is smaller than the first space;a first liquid housed in the first space; anda second liquid housed in the second space;{'b': 1', '2', '1', '2, 'wherein when the volume of the first liquid is set as L and the volume of the second liquid is set as L, L/L is 2.0 to 6.0; and'}wherein the partition part has a breaking strength of 5 to 25 kPa.2. The medical bag according to claim 1 , wherein the partition part is a part formed by sandwiching and melt-bonding the sheet material between an upper mold disposed on an upper side of the sheet material in a vertical direction and having a surface temperature of 130 to 145° C. claim 1 , and a lower mold disposed on a lower side of the sheet material in the vertical direction and having a surface temperature that is 20 to 30° C. lower than the surface temperature of the upper mold.3. The medical bag according to claim 1 , wherein a liquid formed by mixing the first liquid and the second liquid is a peritoneal dialysate.4. The medical bag according to claim 1 , wherein the first liquid has a pH of 4.0 to 6.0.5. The medical bag according to claim 1 , wherein first liquid comprises icodextrin.6. The medical bag according to claim 1 , wherein the second liquid is formulated to adjust a pH of the liquid formed by mixing the first liquid and the second liquid to 6.0 to 7.5.7. The ...

LYOPHILISATE CONTAINER AND INFUSION KIT

A lyophilisate container () comprising a compartment; a wall () limiting the compartment; and a lyophilisate arranged inside the compartment. At least a portion of the wall () is semipermeable allowing vapour permeation in one direction out of the compartment through the wall () and preventing vapour permeation in an opposite direction into the compartment through the wall (). 1. A lyophilisate container comprising;a compartment;a wall limiting the compartment; anda lyophilisate arranged inside the compartment,wherein at least a portion of the wall is semipermeable allowing vapour permeation in one direction out of the compartment through the wall and preventing vapour permeation in an opposite direction into the compartment through the wall.2. The lyophilisate container of claim 1 , wherein the wall comprises a semipermeable membrane which is vapour permeable in the one direction and vapour tight in the opposite direction.3. The lyophilisate container of claim 2 , wherein the wall comprises a frame structure by means of which the semipermeable membrane is spanned.4. The lyophilisate container of claim 1 , comprising an outer encasing and an inner encasing positioned inside the outer encasing claim 1 , wherein the wall is a portion of the inner encasing.5. The lyophilisate container of claim 4 , wherein the compartment is arranged in between the outer encasing and the inner encasing claim 4 , and the at least a portion of the wall is oriented to allow vapour permeation in the one direction from the compartment to the inner encasing through the wall and to prevent vapour permeation in the opposite direction from the inner encasing to the compartment through the wall.6. The lyophilisate container of claim 4 , wherein the compartment is arranged in the inner encasing claim 4 , and the at least a portion of the wall is oriented to allow vapour permeation in the one direction from the compartment to between the outer encasing and the inner encasing through the wall and ...

Lock mechanism, equipment connector, container connector, and connection equipment

A lock mechanism includes an engaged section of a second member and an engagement member of a first member. The engagement member includes an operating section, a fulcrum section configured to contact the second member in a state in which the operating section is pressed, an engaging section engaging with the engaged section, a deformation section configured to be bent to move the engaging section when the operating section is pressed, and a fixing section fixed to the edge of a hole.

INTRADERMAL INJECTION DEVICE

Embodiments herein relate to the field of injections, for instance needle-free injections, and more specifically, to methods and apparatus for spring-driven intramuscular and intradermal injections. Provided in some embodiments are needle-free injectors adapted to deliver intradermal injections, as well as vial adaptors that are adapted to function as spacers when used with a needle-free injection device. 119.-. (canceled)20. A needle-free injection device , comprising:a body terminating in a nozzle;a fluid reservoir housed within the body, the fluid reservoir being adapted to receive a fluid injectate;a plunger disposed within the fluid reservoir;a shaft to which the plunger is mounted such that when the shaft is driven forward, the plunger is responsively driven forward;a spring-driven propulsion system having a first spring adapted to apply force to the shaft and thus to the plunger to cause ejection of the fluid injectate through the nozzle;a lever adapted to arm the spring-driven propulsion system;a rod extending between the lever and the shaft to transmit force between the lever and the shaft via the body of the rod to compress the first spring; anda second spring in operable communication with the lever, the second spring configured to bias the lever towards a home position. This application is a divisional of U.S. patent application Ser. No. 12/824,114, filed Jun. 25, 2010, the entire content of which is incorporated herein by reference.Embodiments herein relate to the field of injections, for instance needle-free injections, and more specifically, to methods and apparatus for spring-driven intramuscular and intradermal injections.Needle-free injection systems provide an alternative to standard fluid delivery systems, which generally use a needle adapted to penetrate the outer surface of a target. Typically, needle-free injection systems are designed to eject the fluid from a fluid chamber with sufficient pressure to allow the fluid to penetrate the target ...

Mechanical Friction Enhancement for Threaded Connection Incorporating Micro-Threads

A medical connector includes a body having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end, a helical thread extending radially outward from a surface of the sidewall and comprising a crest portion, flank portions, and a root portion with the flank portions connecting the root portion to the crest portion, and at least one micro-thread extending radially outward from the surface of the sidewall. At least a portion of the micro-thread is spaced apart from the helical thread. 1. A medical connector comprising:a body having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end;a helical thread extending radially outward from a surface of the sidewall and comprising a crest portion, flank portions, and a root portion, the flank portions connecting the root portion to the crest portion; anda first protrusion extending radially outward from the crest portion of the helical thread.2. The medical connector according to claim 1 , wherein the first protrusion includes a first end and a second end claim 1 , a radial height of the first protrusion at the first end is greater than the radial height of the first protrusion at the second end.3. The medical connector according to claim 2 , wherein an axial width of the first protrusion is larger at the first end than the axial width of the first protrusion at the second end.4. The medical connector according to claim 1 , further comprising a second protrusion extending radially outward from the sidewall of the body.5. The medical connector according to claim 4 , wherein a circumferential length of the first protrusion is longer than a circumferential length of the second protrusion.6. The medical connector according to claim 4 , wherein the second protrusion includes a first end and a second end claim 4 , a radial height of the second protrusion at the first end is greater than the radial height of the second protrusion at the second end ...

FLEXIBLE CONTAINER SYSTEMS AND NOZZLES, AND RELATED METHODS

A container system includes at least one flexible wall defining a compartment containing a dissolvable solid or concentrate, a support adjacent a first end of the at least one flexible wall, and a nozzle assembly coupled to a second end of the at least one flexible wall. The second end of the wall is distal from the first end. The nozzle assembly comprises a hollow body defining a longitudinal axis. The hollow body further defines a plurality of orifices through a wall thereof. Each orifice is able to form a fluid connection between an interior volume within the hollow body and the compartment. Each orifice is configured to deliver liquid from the interior volume to the compartment in a direction having an angle of between 5° and 85° from a direction of the longitudinal axis. Related nozzles and methods are also disclosed. 1. A container system comprising:at least one flexible wall defining a compartment containing a dissolvable solid or concentrate;a support adjacent a first end of the at least one flexible wall; anda nozzle assembly coupled to a second end of the at least one flexible wall, the second end distal from the first end, the nozzle assembly comprising a hollow body defining a longitudinal axis;wherein the hollow body further defines a plurality of orifices through a wall thereof, each orifice able to form a fluid connection between an interior volume within the hollow body and the compartment, and each orifice configured to deliver liquid from the interior volume to the compartment in a direction having an angle of between 5° and 85° from a direction of the longitudinal axis.2. The container system of claim 1 , further comprising a frangible seal configured to limit transfer of material from the compartment through the nozzle assembly until the frangible seal has been breached.3. The container system of claim 2 , wherein the frangible seal comprises an adhesive bonded to the at least one flexible wall within the compartment.4. The container system of ...

Systems and Methods Related to Fluid Pumping

Systems for a plastic pump/actuator capable of containing and pumping organic solvents and lubricants and having a more desirable lubricity within the system. The system has at least two cylinders, with plungers therein, oppositely disposed from each other and configured to operably connect to a pump. 1. A reciprocating actuator assembly comprising:a first cylinder;a first plunger with a piston;a second cylinder configured to be coupled to and in fluid communication with the first cylinder;a second plunger with a piston configured to translate within the second cylinder; anda fluoropolymer coating applied within the first cylinder, within the second cylinder, and to the piston of the first plunger and the piston of the second plunger.2. The actuator assembly of claim 1 , wherein at least one of the first and second cylinders comprise cyclic olefin copolymer (COC).3. The actuator assembly of claim 1 , wherein at least one of the first and second cylinders comprise cyclo-olefin polymer (COP).4. The actuator assembly of claim 1 , wherein the first cylinder has approximately a 1 cc capacity and whereby the static friction between the first cylinder and the first piston is less than about 2.5 N.5. The actuator assembly of claim 1 , wherein the first cylinder has approximately a 3 cc capacity and whereby the static friction between the first cylinder and the first piston is less than about 4.0 N.6. The actuator assembly of further configured to be operatively coupled to a pump.7. The actuator assembly of claim 6 , wherein the first plunger has a first end and a second end claim 6 , wherein the first end of the plunger is received within the first cylinder and the second end of the plunger is received within a pump cylinder.8. The actuator assembly of claim 1 , further comprising a check valve coupled between the first cylinder and the second cylinder.9. The actuator assembly of claim 8 , wherein the check valve is configured to be removably coupled to a third cylinder ...

Adaptor for Coupling to a Medical Container

An adaptor for coupling with a medical container having a collar closed by a septum including: a tubular body closed at a distal end with a transversal wall from which extends a hollow spike, and at a proximal end by a pierceable elastomeric piece including a cavity having a plurality of circumferentially distributed chambers, each chamber being connected to the hollow spike by a radial channel, the tubular body further receiving an intermediate piece including a plurality of through holes aligned on the chambers, a selecting member having a closure wall provided with one opening, capable of rotating so that the opening is successively aligned with each of the through holes, and a gripping member for securing the adaptor to the medical container. Also, an assembly including the adaptor and a medical container. 1. An adaptor for coupling with a medical container having a collar closed by a septum , said septum having an outer surface directed towards an outside of the medical container , the adaptor comprising:a tubular body substantially closed at a distal end with a transversal wall provided with a central hole from which extends a hollow spike in a distal direction for passage of a fluid, a plurality of circumferentially distributed chambers extending from said transversal wall in a proximal direction, said chambers being closed at a proximal end by a pierceable elastomeric piece, each chamber being connected to said hollow spike by a radial channel provided with a closure member, said closure member being capable of transitioning from a locked state, in which it closes the radial channel, to an open state in which it does not close said radial channel, each chamber being filled with decontaminated air and each closure member being in a locked state in a storage state of said adaptor,said tubular body further receiving an intermediate piece located proximally with respect to said pierceable elastomeric piece, said intermediate piece comprising a plurality of ...

Adaptor for Coupling with a Medical Container

An adaptor for coupling with a vial having a collar closed by a septum, the septum having an outer surface directed towards the outside of the vial, the adaptor comprising: a gripping member for securing the adaptor to the vial, the gripping member being capable of being laterally mounted on the collar of the vial and a pierceable elastomeric piece having at least a part intended to be in contact with the outer surface of the septum when the adaptor is secured on the vial. Also, an assembly including such an adaptor and a vial. 1. An adaptor for coupling with a medical container having a collar closed by a septum , said septum having an outer surface directed towards the outside of the medical container , the adaptor comprising:a gripping member for securing the adaptor to the medical container, said gripping member being capable of being laterally mounted on the collar of said medical container,a pierceable elastomeric piece having at least a part intended to be in contact with the outer surface of the septum when said adaptor is secured on said medical container.2. The adaptor of claim 1 , wherein the surface of said part of the pierceable elastomeric piece is complementary to the whole outer surface of the septum.3. The adaptor of claim 1 , further comprising a compressive member for pressing said pierceable elastomeric piece onto said outer surface of the septum claim 1 , when said adaptor is secured on said medical container claim 1 , said compressive member being capable to transition from an inactive state claim 1 , in which it does not exert pressure on said pierceable elastomeric piece claim 1 , to an active state claim 1 , in which it exerts pressure.4. The adaptor of claim 1 , further comprising a fixing system for preventing releasing of said gripping member and definitively securing the adaptor on said medical container.5. The adaptor of claim 1 , further comprising a transversal wall connected to said gripping member claim 1 , said transversal wall ...

EXTRACTION DEVICE FOR A SINGLE EXTRACTION OF A MEDICAMENT FROM A CONTAINER

An extraction device and an extraction kit for one-time extracting a medicament from a container is presented where the extraction device has a housing adapted to non-releasably engage with the container and comprising an axially elongated receptacle, wherein the receptacle is adapted to axially guide a drug delivery device and a piercing member to a distal stop position for penetrating a seal of the container. The device and kit also have at least one fixing member to keep the piercing member in the distal stop position and to support a non-reversible disconnection of the drug delivery device from the piercing member. 115-. (canceled)16. An extraction device for one-time extracting a medicament from a container , the extraction device comprising:a housing adapted to non-releasably engage with the container and comprising an axially elongated receptacle,wherein the receptacle is adapted to axially guide a drug delivery device and a piercing member to a distal stop position for penetrating a seal of the container, and further comprisingat least one fixing member to keep the piercing member in the distal stop position and to support a non-reversible disconnection of the drug delivery device from the piercing member.17. The extraction device according to claim 16 , wherein the fixing member radially inwardly protrudes from an inner side wall of the receptacle.18. The extraction device claim 16 , wherein the receptacle comprises a bottom wall at its distal end providing a distal abutment face for the piercing member claim 16 , wherein the bottom wall further comprises a through opening to receive a neck portion of the container and/or to receive a piercing element of the piercing member.19. The extraction device according to claim 18 , further comprising a tubular shaped fastening member protruding from the bottom wall in distal direction to receive the neck portion of the container claim 18 , wherein the fastening member comprises at least one interlock member to ...

Apparatus for mixing and transferring medications

An apparatus for transferring a chosen quantity of medication from a vial to a container under sterile conditions is described. The present invention further facilitates dissolving solid medications contained in the vial or diluting concentrated medications contained in the vial, and transferring the resulting solutions to the container. The container may be an intravenous infuser.

Adaptor for Coupling to a Medical Container

An adaptor for coupling with a medical container, including: a tubular body receiving a pierceable elastomeric piece, defining an inner cavity of the adaptor, the pierceable elastomeric piece being movable within the tubular body between a first position, in which a distal part of the pierceable elastomeric piece forms a seal of the cavity, and a second position, proximally spaced from the first position, in which the distal part opens the seal of the cavity, an air inlet, a filtering system for filling the inner cavity with decontaminated air, and a gripping member for securing the adaptor to the medical container. Also, an assembly comprising such an adaptor and a medical container. 1. An adaptor for coupling with a medical container having a collar closed by a septum , said septum having an outer surface directed towards an outside of the medical container , the adaptor comprising:a tubular body substantially closed at a distal end with a transversal wall provided with a central hole and substantially closed at a proximal end by a pierceable elastomeric piece, said pierceable elastomeric piece, transversal wall and tubular body together defining an inner cavity of said adaptor, said pierceable elastomeric piece being movable within said tubular body between a first position, in which a distal part of said pierceable elastomeric piece forms a seal of said central hole, and a second position, proximally spaced from said first position, in which said distal part opens the seal of said central hole,an air inlet for allowing air from the outside to enter said inner cavity at least when said pierceable elastomeric piece moves from the first position to the second position, said air inlet comprising a filtering system for decontaminating said entering air before it reaches said inner cavity, anda gripping member for securing the adaptor to the medical container, so that a distal surface of said transversal wall is brought in contact with the outer surface of said septum ...

Universal fluid container adapter

Various embodiments are generally directed to fluid container adapters that couple with a fluid container and enable different systems, such as endoscopic systems, to access the contents of the fluid container, such as via a tubing set. Several embodiments are particularly directed to a fluid container adapter that punctures a fluid container to couple with and gain access to the contents of the fluid container. In one embodiment, for example, a platform may be used to support a fluid container as one or more penetration members attached to a crossmember are advanced into the fluid container along rails connected between the platform and the crossmember. In such embodiments, the one or more penetration members may include lumens to enable a tubing set to access the contents of the fluid container.

COMPONENT MIXING DEVICE AND COMPONENT MIXING METHOD

The present relates to a component mixing device comprising a central unit () and a disposable cartridge, said central unit () comprising a control unit, a plurality of vial positioning elements () and a cavity for receiving said disposable cartridge, and said disposable cartridge () comprising a tubing circuitry adapted to put the components housed in said plurality of vials into communication for mixing, characterized in that the mixing device is adapted to put each vial into communication with each other through said tubing circuitry of said disposable cartridge () and mixing said components through an compressed air mechanism () located in said central unit () and controlled by said control unit. 129-. (canceled)30. A disposable cartridge to be used with a separated central unit in a component mixing device , comprising: at least two circuitry inlets each being adapted to enter in fluid communication with a vial to permit insertion of content of each vial within said circuitry,', 'at least one circuitry outlet for outputting a mixed product from the disposable cartridge and', 'a plurality of valves adapted to be controlled by a control unit of said central unit in order to create a specific path within said circuitry between said inlets and said outlet,', 'wherein said circuitry is adapted to enter in fluid communication with a pressure gradient generating mechanism of said central unit in order to generate a circuitry content driving force within it., 'a rigid microfluidic circuitry including'}31. The disposable cartridge according to claim 30 , wherein said circuitry is adapted to put at least a first vial and a second vial in fluid communication so as to mix reagent content of the first vial with reagent content of the second vial.32. The disposable cartridge according to claim 30 , further comprising at least one storing vessel for storing an intermediary product obtained through the mixing of contents of at least two vials.33. The disposable cartridge ...

ENTERAL FEEDING ADAPTERS AND METHODS OF USING THE ENTERAL FEEDING ADAPTERS

An adapter is provided for connecting a container of flowable material, such as enteral feed formula in a laminated paper container, to a feeding tube to enable bolus feeding. The adapter can transfer the flowable material from the container by piercing the container and/or a cover of the container. The adapter can form a fluid-tight friction seal on the container. In some embodiments, the adapter has a reusable tube vent long enough to be positioned in the air gap of the container when the container is inverted by a user. 1. An adapter for fluidly connecting a syringe to a container containing a composition , the syringe coupled to an enteral feeding line , the adapter comprising:a body comprising a bottom end that defines an opening and a spike;a fluid exit port extending from a top end of the body, the top end facing an opposite direction from the bottom end, the body comprising an internal chamber that fluidly connects the opening to the fluid exit port, the fluid exit port configured to direct the composition to the syringe coupled to the enteral feeding line; andone or more interface surfaces extending radially from the body, the one or more interface surfaces optionally comprising ribs configured to create a gap between the syringe and a portion of the body between the ribs when the adapter is inserted into the syringe.2. The adapter of claim 1 , wherein the bottom end comprises a wall that forms the spike and also defines at least a portion of the opening.3. The adapter of claim 1 , wherein the opening of the body lies in a plane positioned at an angle between ten degrees and eighty degrees relative to at least one of (i) a side wall of the body or (ii) a longitudinal axis of the body.4. The adapter of claim 1 , wherein the body is cylindrical.5. The adapter of claim 1 , wherein at least a portion of the body is transparent.6. A kit comprising the adapter of and further comprising at least one of (i) the container containing the composition or (ii) the ...

ENTERAL FEEDING ADAPTER AND METHOD OF USE

An enteral feeding adapter system for use with a bottle cap having a dispensing opening, and an oral syringe having a male syringe element. The system includes a cap adapter having a male adapter element configured to be insertable into the dispensing opening to place the cap adapter in fluid communication with the bottle cap. The cap adapter further includes a male ENFit connector in fluid communication with the male adapter element. The enteral feeding adapter system further includes a syringe adapter having a female ENFit connector configured to be selectively engageable with the male ENFit connector to place the syringe adapter in fluid communication with the cap adapter. The syringe adapter further includes a female adapter element in fluid communication with the female ENFit connector and configured to receive the male syringe element to place the syringe adapter element in fluid communication with the oral syringe. 1. An enteral feeding adapter system for use with a bottle cap having a dispensing opening , and an oral syringe having a male syringe element , the enteral feeding adapter system comprising: a male adapter element configured to be insertable into the dispensing opening to place the cap adapter in fluid communication with the bottle cap; and', 'a first male ENFit connector in fluid communication with the male adapter element; and, 'a cap adapter having a female ENFit connector configured to be selectively engageable with the first male ENFit connector to place the syringe adapter in fluid communication with the cap adapter; and', 'a female adapter element in fluid communication with the female ENFit connector and configured to receive the male syringe element to place the syringe adapter element in fluid communication with the oral syringe., 'a syringe adapter having2. The enteral feeding adapter system recited in claim 1 , wherein the male adapter element includes a tapered outer surface having a minimum outer diameter less than a diameter of the ...

BLUNT CANNULA NEEDLE DEVICE

A needle device has a needle assembly including a hub having one end fitted with a blunt cannula. The blunt cannula has a base section, a central section and a shaft having a distal apertured end. The needle of the needle assembly extends through an internal passage of the blunt cannula and is sealingly fitted to a portion of the internal passage. The hub of the needle assembly has another end connectable to a syringe. When the device is connected to a syringe, a fluid communication path is established between the apertured end of the shaft and the interior of the syringe via the lumen of the needle. The shaft of the blunt cannula is usable to pierce the seal of a fluid store while maintaining the needle in an unused state for subsequent patient use. The distal end of the shaft may be protected by an end cap. 1. A medical device comprising: a base section adapted to couple to a needle hub;', 'a central section distally adjacent to the base section having an internal central passage;', 'a shaft extending distally from the central section, the shaft having an internal shaft passage in alignment with the central passage along a longitudinal axis to form a longitudinal passage along the blunt cannula; and, 'a blunt cannula having'}a needle assembly having a needle extending from a needle hub;wherein the longitudinal passage is configured to sealingly receive the needle from the needle assembly so that a seal fit is formed between the needle and the longitudinal passage at at least a portion thereof when the needle assembly and the blunt cannula are coupled to each other; andwherein the needle assembly with the blunt cannula coupled thereto is adapted to be attached to a syringe for use with a fluid store.2. The device of claim 1 ,wherein the shaft of the blunt cannula comprises an apertured end; andwherein the needle comprises a sharp distal end;whereby the apertured end is positioned distally from the sharp distal end when the needle is appropriately positioned within ...

Device for Transferring a Fluid Between a Storage Container and at Least One Further Container for Use

A device serves for transferring a fluid between a storage container and at least one further container for use. Said transfer device comprises a sealing section by means of which a main part of the transfer device sealingly rests on the storage container. A hollow-needle assembly comprises a hollow needle which can be moved between a retracted resting position and a deployed connecting position, the assembly, in the connecting position, providing a fluid connecting channel between the storage container and the transfer device. The hollow-needle assembly can be moved by means of a pressure actuating element. During said movement, the pressure actuating element is primarily connected to the sleeve of the hollow needle so as to be resistant to shear forces. A guiding device serves to axially guide the pressure actuating element on the main part. Said guiding device has at least one guiding pin. Said guiding pin slides in at least one associated guiding groove during movement. The guiding device is designed such that the movement of the hollow-needle assembly from the resting position to the connecting position is irreversible. In this way, the hollow needle can be moved from the resting position to the connecting position in an operationally safe manner.

MEDICAL LIQUID COLLECTION INJECTOR

A tube end () of a barrel () of an injector () includes a tubular portion () on which a spiral projection () is formed, and an inner circumferential surface of the tubular portion is a female tapered surface (). A small-diameter portion () is formed between a liquid storing portion () into which a plunger () is inserted and the tubular portion (). A base end () of a liquid collection needle () is fluid-tightly connected to the small-diameter portion (), and a leading end of the liquid collection needle () protrudes from the tube end (). 1. A medical liquid collection injector comprising:a tube-shaped barrel that includes an opening at one end and a tube end at another end;a plunger inserted into the opening of the barrel; anda tube-shaped liquid collection needle,wherein the tube end includes a cylindrically-shaped tubular portion and a spiral projection that is formed on an outer circumferential surface of the tubular portion,an inner circumferential surface of the tubular portion is a female tapered surface with an inner diameter that becomes larger as a leading end is approached,the barrel includes a small-diameter portion with an inner diameter that is relatively small between a liquid storing portion in which the plunger is inserted and the tubular portion, anda base end of the liquid collection needle is fluid-tightly connected to the small-diameter portion, and a leading end of the liquid collection needle protrudes from the tube end.2. The medical liquid collection injector according to claim 1 , whereinthe barrel and the liquid collection needle are separate parts, andthe liquid collection needle is detachably mounted on the tube end.3. The medical liquid collection injector according to claim 2 , wherein a fitting shape that fits in the inner circumferential surface of the tubular portion is formed on the liquid collection needle.4. The medical liquid collection injector according to claim 1 , whereinthe barrel and the liquid collection needle constitute a ...

NEEDLE-LESS VIAL ASSEMBLY FOR USE WITH NEEDLE-FREE SYSTEM

A needle-less vial assembly that includes a substance transfer assembly configured to telescopically engage with a vial neck of a vial. A first portion of the substance transfer assembly is configured to sealingly engage with an interior wall of the vial neck, where the first portion includes a first inlet configured to receive a substance from the vial. A second portion of the substance transfer assembly is configured to matingly engage with a syringe, and includes an outlet configured to dispense the substance to the syringe. A channel is defined through the first portion and the second portion, thereby enabling fluid communication of the substance from the vial to the syringe via the first inlet and the outlet.

MULTI-MIX INFUSION BAG

A multi-mix infusion bag is provided. The multi-mix infusion bag includes a lower portion and an upper portion. The lower portion has a lower chamber and the upper portion includes a plurality of chambers. Each chamber is separated and contains a fluid agent. The multi-mix infusion bag is configured to transfer each fluid agent within each chamber of the upper portion into the lower chamber for mixing. The multi-mix infusion bag may include dispensing devices associated with each chamber, wherein the dispensing devices operate to transfer the fluid agents into the lower chamber for mixing.