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Применить Всего найдено 165883. Отображено 100.
10-09-2007 дата публикации

УСТАНОВКА ДЛЯ ВЫДЕЛЕНИЯ ДИГИДРОКВЕРЦЕТИНА ИЗ ДРЕВЕСИНЫ ЛИСТВЕННИЦЫ

Номер: RU0000066199U1

Установка для выделения дигидрокверцетина из древесины лиственницы, содержащая бункер-питатель, узел подачи растворителя, подогреватель, сборник экстракта-растворителя, и по меньшей мере две линии экстракт-растворителей для выделения дигидрокверцетина, каждая из которых содержит подводящие и отводящие вентили, реактор-экстрактор, и пульповый насос, отличающаяся тем, что в нее введен конденсатор паров экстракта-растворителя, а в каждой из линий установлены подогреватель и пульсатор, при этом каждый из экстракторов соединен одним из входов с выходом бункера-питателя, другим входом через первый подводящий вентиль - с узлом подачи экстракта, одним из выходов связан со входом конденсатора, выход которого через вторые подающие вентили также соединен с другим входом каждого из экстракторов, другой выход каждого из которых через последовательно соединенные подогреватель, насос, пульсатор и третий подающий вентиль связан с третьим входом каждого из экстракторов, третьи выходы которых через третий насос и четвертый вентиль соединены со сборником экстракта-растворителя. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 66 199 (13) U1 (51) МПК A61K 36/00 (2006.01) C07D 311/40 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ, ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ (21), (22) Заявка: 2007116823/22 , 03.05.2007 (24) Дата начала отсчета срока действия патента: 03.05.2007 (45) Опубликовано: 10.09.2007 (73) Патентообладатель(и): ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ЭЛИОР" (RU), Мальчиков Евгений Леонидович (RU) U 1 6 6 1 9 9 R U Ñòðàíèöà: 1 U 1 Формула полезной модели Установка для выделения дигидрокверцетина из древесины лиственницы, содержащая бункер-питатель, узел подачи растворителя, подогреватель, сборник экстракта-растворителя, и по меньшей мере две линии экстракт-растворителей для выделения дигидрокверцетина, каждая из которых содержит подводящие и отводящие вентили, реактор-экстрактор, и пульповый насос, отличающаяся тем, что в нее введен ...

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20-11-2012 дата публикации

ИЗДЕЛИЕ ДЛЯ ФИТОТЕРАПИИ

Номер: RU0000122020U1

1. Изделие для фитотерапии, включающее чехол в виде, по меньшей мере, двух соединенных между собой слоев ткани или нетканого материала с наполнителем, содержащим, по меньшей мере, один фитотерапевтический ингредиент из лекарственных растений, соответствующий лечению и/или профилактике конкретных заболеваний, отличающееся тем, что выполнено разделенным на ячейки, преимущественно простегиванием, наполнитель выполнен из сушеной травы нейтрального действия, при этом один из слоев чехла выполнен из влагонепроницаемого материала типа ламинированный медицинский спанбонд или спанлейс, а второй из слоев чехла выполнен из влагопроницаемого материала. 2. Изделие для фитотерапии по п.1, отличающееся тем, что выполнено в виде подушки, коврика, валика, аппликатора, повязки, шапочки, носка, рукавицы. 3. Изделие для фитотерапии по п.1, отличающееся тем, что слой чехла из влагопроницаемого материала выполнен из материала типа марля, ситец или влагопроницаемый медицинский спанбонд или спанлейс. 4. Изделие для фитотерапии по п.1, отличающееся тем, что в качестве фитотерапевтического ингредиента из лекарственных растений используют красный корень. 5. Изделие для фитотерапии по п.1, отличающееся тем, что в качестве фитотерапевтического ингредиента из лекарственных растений используют смесь плодов можжевельника и листьев березы. 6. Изделие для фитотерапии по п.1, отличающееся тем, что в качестве фитотерапевтического ингредиента из лекарственных растений используют цветки ромашки. 7. Изделие для фитотерапии по п.1, отличающееся тем, что в качестве фитотерапевтического ингредиента из лекарственных растений используют смесь из цветков, листьев и плодов арники горной, березы, календулы, крапивы, рябины, синюхи, хвоща полевого, частеца, боярышника, донника, мокрицы, липы, пижмы, подорожника, сушеницы. 8. Изделие для фитотерапии по п.1, отличающееся тем, что в качестве фитотерапевтического ингредиента из лекарственных растений используют смесь из цветков, листьев и плодов мать-и-мачехи, ...

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27-06-2014 дата публикации

ПОДУШКА КЕДРОВАЯ ЛЕЧЕБНО-ПРОФИЛАКТИЧЕСКАЯ

Номер: RU0000142469U1

Подушка кедровая лечебно-профилактическая, содержащая воздухопроницаемый чехол с наполнителем в виде растительного сырья древесного происхождения, отличающаяся тем, что содержит наполнитель из растительного сырья древесного происхождения в виде стружки из древесины кедра корейского (сосны корейской) размером не более 2,0×0,5×0,1 см, занимающей не более 80% объема чехла. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 142 469 U1 (51) МПК A61K 36/15 (2006.01) A47G 9/10 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ 2013146443/15, 17.10.2013 (24) Дата начала отсчета срока действия патента: 17.10.2013 (73) Патентообладатель(и): Горовой Александр Иванович (RU) (45) Опубликовано: 27.06.2014 Бюл. № 18 (54) ПОДУШКА КЕДРОВАЯ ЛЕЧЕБНО-ПРОФИЛАКТИЧЕСКАЯ U 1 1 4 2 4 6 9 R U Стр.: 1 U 1 Формула полезной модели Подушка кедровая лечебно-профилактическая, содержащая воздухопроницаемый чехол с наполнителем в виде растительного сырья древесного происхождения, отличающаяся тем, что содержит наполнитель из растительного сырья древесного происхождения в виде стружки из древесины кедра корейского (сосны корейской) размером не более 2,0×0,5×0,1 см, занимающей не более 80% объема чехла. 1 4 2 4 6 9 Адрес для переписки: 680021, Хабаровский край, г. Хабаровск, ул. Ленинградская, 44, Хабаровский ЦНТИ R U Приоритет(ы): (22) Дата подачи заявки: 17.10.2013 (72) Автор(ы): Горовой Александр Иванович (RU), Тагильцев Юрий Григорьевич (RU), Колесникова Римма Дмитриевна (RU), Цюпко Владимир Александрович (RU) RU 5 10 15 20 25 30 35 40 45 142 469 U1 Техническое решение относится к медицине и может быть использовано в качестве средства для фитотерапии при лечении и профилактике заболеваний сердечнососудистой, иммунной, бронхо-легочной, нервной систем человека в медицинских учреждениях и в быту. Известны подушки для сна и отдыха, обладающие лечебно-профилактическими свойствами, содержащие чехол и природный растительный наполнитель в виде ...

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05-01-2012 дата публикации

Process for production of orally ingestible composition containing arabinofuranosyl vitexin, and use of the composition

Номер: US20120004193A1
Автор: Shuichi Kusano
Принадлежит: Fuji Sangyo Co Ltd

A method for producing an orally ingestible composition containing an arabinofuranosyl vitexin and/or a hydrolysate thereof by using Basella alba as a raw material. The product of such method has a sedative effect and a sleep-inducing effect.

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20-09-2014 дата публикации

ДОБАВКА ДИЕТИЧЕСКАЯ "ЧАЙ ИЗ АРОМАТИЧЕСКИХ ТРАВ СЕРИИ "НИКИТСКИЙ САД"

Номер: RU0000145630U1

1. Добавка диетическая представляет собой смесь сухих измельченных растений или их частей, содержащая душицу обыкновенную, которая складывается из базового и дополнительных компонентов, при этом базовым компонентом служит душица обыкновенная, а дополнительные компоненты выбраны из ряда: чабрец обыкновенный, иссоп лекарственный, кошачья мята лимонная, эльсгольция Стаунтона, бессмертник итальянский, тысячелистник обыкновенный, мята перечная, фенхель обыкновенный. 2. Добавка диетическая по п.1 отличается тем, что в состав дополнительных компонентов входят чабрец обыкновенный, иссоп лекарственный, кошачья мята лимонная в следующем количественном соотношении базового и дополнительных компонентов: душица обыкновенная: чабрец обыкновенный: иссоп лекарственный: кошачья мята лимонная как: 5 : 5 : 3,6 : 6,4 по массе соответственно. 3. Добавка диетическая по п.1 отличается тем, что в состав дополнительных компонентов входят эльсгольция Стаунтона, бессмертник итальянский, тысячелистник обыкновенный в следующем количественном соотношении базового и дополнительных компонентов: душица обыкновенная: эльсгольция Стаунтона: бессмертник итальянский: тысячелистник обыкновенный как: 2,6 : 4 : 1,7 : 1,7 по массе соответственно. 4. Добавка диетическая по п.1 отличается тем, что в состав дополнительных компонентов входят мята перечная, эльсгольция Стаунтона, фенхель обыкновенный в следующем количественном соотношении базового и дополнительных компонентов: душица обыкновенная: мята перечная: эльсгольция Стаунтона: фенхель обыкновенный как: 6,25 : 3: 9,25 : 6,5 по массе соответственно. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 145 630 U1 (51) МПК A23L 1/29 (2006.01) A23F 3/00 (2006.01) A61K 36/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ Государственная регистрация полезной модели осуществлена по заявлению о признании действия исключительного права на территории Российской Федерации на основании статьи 13¹ Федерального закона от 18 ...

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27-01-2015 дата публикации

СПОСОБ ОПРЕДЕЛЕНИЯ АНТИМИКРОБНОЙ АКТИВНОСТИ ДЕЗИНФИЦИРУЮЩИХ СРЕДСТВ

Номер: RU0000150146U1

Способ определения антимикробной активности дезинфицирующих средств, который включает использование тест-поверхности для нанесения суспензии микроорганизмов, подготовку тест-поверхности для обработки дезинфицирующим раствором и обработку ее дезинфицирующим средством, выдерживание времени экспозиции, учет результатов путем подсчета колоний на твердой питательной среде после термостатирования, отличающийся тем, что используют стеклянную тест-поверхность размером 3×7,5 см, на которую наносят твёрдую питательную среду, а поверх нее - суспензию микроорганизмов, далее выдерживают тест-поверхность при комнатной температуре в течение 10-15 мин и обрабатывают дезинфицирующим средством, после экспозиции проводят термостатирование тест-поверхности и подсчитывают колонии на твердой питательной среде, нанесенной поверх тест-поверхности. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (51) МПК A61K 36/00 (13) 150 146 U1 (2013.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ Государственная регистрация полезной модели осуществлена по заявлению о признании действия исключительного права на территории Российской Федерации на основании статьи 13¹ Федерального закона от 18 декабря 2006 года № 231-ФЗ «О введении в действие части четвертой Гражданского кодекса Российской Федерации» (21)(22) Заявка: 2014150914/93, 21.11.2014 (24) Дата начала отсчета срока действия патента: Приоритет(ы): Дата приоритета: 10.06.2013 Патент № 86029 (UA) (45) Опубликовано: 27.01.2015 Бюл. № 3 Адрес для переписки: 295034, Республика Крым, г. Симферополь, ул. Куйбышева, 19, кв. 46, Плотниковой М.А. 1 5 0 1 4 6 R U Формула полезной модели Способ определения антимикробной активности дезинфицирующих средств, который включает использование тест-поверхности для нанесения суспензии микроорганизмов, подготовку тест-поверхности для обработки дезинфицирующим раствором и обработку ее дезинфицирующим средством, выдерживание времени экспозиции, учет результатов путем подсчета колоний на ...

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27-01-2015 дата публикации

СПОСОБ СНИЖЕНИЯ МИКРОБНОГО ЗАГРЯЗНЕНИЯ ВОЗДУХА ЖИЛЫХ ПОМЕЩЕНИЙ, ОБОРУДОВАННЫХ СПЛИТ-СИСТЕМОЙ

Номер: RU0000150147U1

Способ снижения микробного загрязнения воздуха жилых помещений, оборудованных сплит-системой, путем добавления в атмосферу помещений композиции эфирных масел Полиол, отличающийся тем, что композицию эфирных масел Полиол наносят на дезодорирующий фильтр сплит-системы один раз в течение 10-12 ч в количестве 2,5 мг на каждый кубический метр объема помещения. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (51) МПК A61K 36/00 (13) 150 147 U1 (2013.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ Государственная регистрация полезной модели осуществлена по заявлению о признании действия исключительного права на территории Российской Федерации на основании статьи 13¹ Федерального закона от 18 декабря 2006 года № 231-ФЗ «О введении в действие части четвертой Гражданского кодекса Российской Федерации» (21)(22) Заявка: 2014150916/93, 21.11.2014 (24) Дата начала отсчета срока действия патента: Приоритет(ы): Дата приоритета: 18.12.2012 Патент № 80436 (UA) (73) Патентообладатель(и): Козуля Сергей Валериевич (RU) Адрес для переписки: 295034, Республика Крым, г. Симферополь, ул. Куйбышева, 19, кв. 46, Плотниковой М.А. R U 1 5 0 1 4 7 Формула полезной модели Способ снижения микробного загрязнения воздуха жилых помещений, оборудованных сплит-системой, путем добавления в атмосферу помещений композиции эфирных масел Полиол, отличающийся тем, что композицию эфирных масел Полиол наносят на дезодорирующий фильтр сплит-системы один раз в течение 10-12 ч в количестве 2,5 мг на каждый кубический метр объема помещения. Стр.: 1 U 1 U 1 (54) СПОСОБ СНИЖЕНИЯ МИКРОБНОГО ЗАГРЯЗНЕНИЯ ВОЗДУХА ЖИЛЫХ ПОМЕЩЕНИЙ, ОБОРУДОВАННЫХ СПЛИТ-СИСТЕМОЙ 1 5 0 1 4 7 (45) Опубликовано: 27.01.2015 Бюл. № 3 R U 18.12.2012 (72) Автор(ы): Козуля Сергей Валериевич (RU), Бобрик Юрий Валериевич (RU), Пьянков Александр Федорович (RU) RU 5 10 15 20 25 30 35 40 45 150 147 U1 Полезная модель относится к области медицины, а именно к гигиене и может быть использована для снижения микробного ...

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10-09-2016 дата публикации

СПОСОБ РЕАБИЛИТАЦИИ ДЕТЕЙ С ПЕРВИЧНОЙ АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИЕЙ

Номер: RU0000164764U1

Способ реабилитации детей с первичной артериальной гипертензией, включающий использование санаторно-курортных факторов, назначение низкокалорийной диеты, лечебной физкультуры, антистрессовой групповой психотерапии, массажа воротниковой зоны, применение йодобромных ванн и электросонтерапии в индивидуально подобранной частоте, отличающийся тем, что предварительно определяют в сыворотке крови показатели уровня инсулина, лептина, грилина натощак, а также липидов, базальной и постпрандиальной глюкозы и при выявленных изменениях данных показателей дополнительно назначают детям с 12 лет фитоминеральный комплекс Гуна Брайн в дозе по одной таблетке два раза в день курсом 16-18 дней. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 164 764 U1 (51) МПК A61B 5/145 (2006.01) A61K 36/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ Государственная регистрация полезной модели осуществлена по заявлению о признании действия исключительного права на территории Российской Федерации на основании статьи 13¹ Федерального закона от 18 декабря 2006 года № 231-ФЗ «О введении в действие части четвертой Гражданского кодекса Российской Федерации» (21)(22) Заявка: 2016122519/93, 07.06.2016 (24) Дата начала отсчета срока действия патента: Приоритет(ы): Дата приоритета: 16.05.2013 Патент № 82008 (UA) (73) Патентообладатель(и): Алёшина Ольга Константиновна (RU) 1 6 4 7 6 4 R U (54) СПОСОБ РЕАБИЛИТАЦИИ ДЕТЕЙ С ПЕРВИЧНОЙ АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИЕЙ (57) Реферат: Способ реабилитации детей с первичной частоте. При этом предварительно определяют артериальной гипертензией включает в сыворотке крови показатели уровня инсулина, использование санаторно-курортных, факторов, лептина, грилина натощак, а также липидов, назначение низкокалорийной диеты, лечебной базальной и постпрандиальной физкультуры,. антистрессовой групповой глюкозы и при выявленных изменениях психотерапии, массажа воротниковой зоны, данных показателей дополнительно назначают применение ...

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10-09-2016 дата публикации

СПОСОБ ЛЕЧЕНИЯ НЕАЛКОГОЛЬНОЙ ЖИРОВОЙ БОЛЕЗНИ ПЕЧЕНИ

Номер: RU0000164770U1

Способ лечения неалкогольной жировой болезни печени, включающий использование тулипа и урсофалька в суточной дозе 15 мг/кг массы тела, отличающийся тем, что дополнительно применяют препарат лозартан в дозе 50 мг ежедневно, а препарат тулип назначают в дозе 10 мг сутки, курс терапии составляет 5-6 месяцев. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 164 770 U1 (51) МПК A61K 36/00 (2013.01) A61K 35/00 (2013.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ Государственная регистрация полезной модели осуществлена по заявлению о признании действия исключительного права на территории Российской Федерации на основании статьи 13¹ Федерального закона от 18 декабря 2006 года № 231-ФЗ «О введении в действие части четвертой Гражданского кодекса Российской Федерации» (21)(22) Заявка: 2016122525/93, 07.06.2016 (24) Дата начала отсчета срока действия патента: Приоритет(ы): Дата приоритета: 15.02.2013 Патент № 82250 (UA) Адрес для переписки: 295006, Республика Крым, г. Симферополь, бульвар Ленина, 5/7, Медицинская академия имени С.И.Георгиевского ФГАОУ ВО "КФУ им. В.И.Вернадского", Плотниковой М.А. 1 6 4 7 7 0 (45) Опубликовано: 10.09.2016 Бюл. № 25 (73) Патентообладатель(и): Федеральное государственное автономное образовательное учреждение высшего образования "Крымский федеральный университет имени В.И.Вернадского" (ФГАОУ ВО "КФУ им. В.И.Вернадского") (RU), Стилиди Елена Игоревна (RU) R U 15.02.2013 (72) Автор(ы): Стилиди Елена Игоревна (RU), Кляритская Ирина Львовна (RU) R U 1 6 4 7 7 0 Формула полезной модели Способ лечения неалкогольной жировой болезни печени, включающий использование тулипа и урсофалька в суточной дозе 15 мг/кг массы тела, отличающийся тем, что дополнительно применяют препарат лозартан в дозе 50 мг ежедневно, а препарат тулип назначают в дозе 10 мг сутки, курс терапии составляет 5-6 месяцев. Стр.: 1 U 1 U 1 (54) СПОСОБ ЛЕЧЕНИЯ НЕАЛКОГОЛЬНОЙ ЖИРОВОЙ БОЛЕЗНИ ПЕЧЕНИ RU 5 10 15 20 25 30 35 40 45 164 770 U1 Полезная модель ...

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10-09-2016 дата публикации

СПОСОБ ДИАГНОСТИКИ ПЕЧЕНОЧНОЙ ЭНЦЕФАЛОПАТИИ

Номер: RU0000164771U1

Способ диагностики печеночной энцефалопатии, включающий определение уровня аммиака сыворотки крови, проведение теста связи чисел, оценку степени энцефалопатии по времени прохождения теста и уровню аммиака сыворотки крови, отличающийся тем, что дополнительно используют гепатоанализатор для определения критической частоты мельканий и при ее значении 39-36 Гц регистрируют минимальную печеночную энцефалопатию, значение критической частоты мелькания 35,9-32 Гц соответствует I степени печеночной энцефалопатии, 31,9-28 Гц соответствует II степени печеночной энцефалопатии, а ниже 27,9 Гц - III степени печеночной энцефалопатии. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 164 771 U1 (51) МПК A61K 36/00 (2012.01) A61K 35/00 (2012.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ Государственная регистрация полезной модели осуществлена по заявлению о признании действия исключительного права на территории Российской Федерации на основании статьи 13¹ Федерального закона от 18 декабря 2006 года № 231-ФЗ «О введении в действие части четвертой Гражданского кодекса Российской Федерации» (21)(22) Заявка: 2016125505/93, 24.06.2016 (24) Дата начала отсчета срока действия патента: (73) Патентообладатель(и): Максимова Елена Владимировна (RU) Приоритет(ы): Дата приоритета: 06.12.2011 Патент № 70779 (UA) 1 6 4 7 7 1 R U (54) СПОСОБ ДИАГНОСТИКИ ПЕЧЕНОЧНОЙ ЭНЦЕФАЛОПАТИИ (57) Реферат: Способ диагностики печеночной частоты мельканий 39-36 Герц определяют энцефалопатии включает определение уровня минимальную степень печеночной аммиака сыворотки крови, проведение теста связи энцефалопатии. Значение критической частоты чисел, оценку степени энцефалопатии по времени мельканий 35,9-32 Герц соответствует I степени прохождения теста и уровню аммиака сыворотки печеночной энцефалопатии, 31,9-28 Герц крови. Дополнительно используют соответствует II степени печеночной гепатоанализатор для определения критической энцефалопатии, а ниже 27,9 Герц - III степени ...

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19-01-2012 дата публикации

Enhanced Natural Colors

Номер: US20120014934A1
Принадлежит: RFI LLC

A natural color is concentrated to intensify color range and to provide useful amounts of one or more of anti-oxidant, nutritional, and anti-inflammatory compounds derived from one or more pigment sources. In a preferred embodiment, the pigment source is a fruit, a vegetable, a legume, a spice, algae, or a combination thereof.

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02-02-2012 дата публикации

Compositions and methods for mycotoxin decontamination of animal feed, food, soil and plants using biomass of filamentous fungi and its selected components

Номер: US20120027747A1
Принадлежит: CUBENA Inc

A method of rendering harmless mycotoxins contaminating food, animal feed and assisting infection of plant hosts by microbial parasites is proposed. The method comprises binding mycotoxins by a novel adsorbent, consisting partially or in full of the biomass of filamentous fungi or isolated fungal biomass components, such as chitin, chitozan and hyrdophobins, or fungal biomass enriched in its capacity to bind said mycotoxins using fungal species and strain selection, genetic engineering of fungi, modification of fungal fermentation conditions and downstream physical and chemical treatment of fungal biomass, such as milling or micronization in a dry state. The resulting adsorbent can bind a wide range of mycotoxins, including the ones difficult to bind (Ochratoxin, T-2, DON, NIV) using a current generation of mycotoxin adsorbents based on clay, resins, yeast and bacterial biomass. The adsorbent can be used as an animal feed additive, functional food additive and agricultural fungistatic/fungicide.

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09-02-2012 дата публикации

Formulation for Prevention and Treatment of Bacterial Infections and Preparation Thereof

Номер: US20120034325A1
Принадлежит: Individual

The invention provides a formulation for the prevention and treatment of bacterial infections by administering an effective amount of the formulation comprising an extract of at least one plant selected from Allium sativum, Acorus calamus, Alstonia scholaris, Carissa spinarum, Cissampelos pareria, Chenopodium ambrosioides, Moringa olifera, Paederia foetida, Shorea robusta, Piper nigrum, Pueraria tuberosa, Ocimum sanctum, Terminalia bellirica, Tinospora cordifolia and Zingiber officinale , and a combination thereof. The invention also provides a process for preparing and method of using the same.

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23-02-2012 дата публикации

Methods of treating cellulite

Номер: US20120045531A1
Принадлежит: Individual

Provided are methods of treating cellulite, the methods comprising applying to skin in need of cellulite treatment a composition comprising paulownin or an extract of Paulownia wood.

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01-03-2012 дата публикации

BIOLOGICALLY ACTIVE COMPOSITIONS FROM Schisandra chinensis FOR TREATING COLORECTAL CANCER

Номер: US20120052142A1
Автор: John Noel GNABRE
Принадлежит: Dr Chang Naturals LLC

A biologically active composition to treat colorectal cancer includes an extract of the plant Schisandra chinensis and a suitable pharmaceutical formulation. The extract can be at least one of gomisin A, angeloylgomisin H, deoxyschisandrin and gomisin N, showing activities against human tumor cell line HT-29 in the range of about 716 μM to about 43 μM. A suitable pharmaceutical formulation can be any one of a pill, a tablet, a capsule, a liquid solution, a liquid suspension, a powder, an intravenous solution, a gel and a suppository form. The extract is prepared by grinding the dried berries, extracting with hexane, extracting the marc with dichloromethane, extracting the dichloromethane soluble fraction with ethyl acetate, removing fatty materials in the dichloromethane-ethyl acetate soluble fraction with hexane, and fractionating the total hexane insoluble material extract using analytical high performance liquid chromatography equipped with automated repeat injection/collection cycles.

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29-03-2012 дата публикации

Method Of Obtaining Antioxidant From Roasted Coffee Beans, The Antioxidant Thus Obtained, And Food Containing The Same

Номер: US20120076907A1
Принадлежит: Individual

An antioxidant originating in coffee beans is provided. A method which comprises contacting a water extract of roasted coffee or an aqueous solution of the extract with an adsorbent and then eluting an antioxidant adsorbed by the adsorbent with an organic solvent or an aqueous organic solvent.

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05-04-2012 дата публикации

Compositions and Methods for Treatment and Management of Pain

Номер: US20120082739A1
Автор: Reza Ghorbani
Принадлежит: Individual

Disclosed herein are compositions and methods for the treatment and management of pain in a subject, comprising topically or orally administering a therapeutically effective amount of a composition comprising herbal extracts and compound mixtures to a subject. The composition includes turmeric extract, Boswellia extract, ginger extract, holy basil extract, rosemary extract, white willow extract and alpha lipolic acid

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17-05-2012 дата публикации

Bioactive botanical cosmetic compositions and processes for their production

Номер: US20120121739A1
Автор: Michael Koganov
Принадлежит: AKZO NOBEL SURFACE CHEMISTRY LLC

The present invention is directed to bioactive botanical cosmetic compositions derived from membrane and cell serum fractions of plant cell juice. The present invention also relates to the methods for preparing these bioactive botanical cosmetic compositions and the uses of these compositions in various cosmetic formulations and as topical skin cosmetic applications.

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24-05-2012 дата публикации

Combination herbal product to benefit respiratory tract in people exposed to smoke

Номер: US20120128801A1
Принадлежит: Aadvantics Pharmaceuticals Inc

An herbal composition for providing a beneficial effect to the respiratory tract. The composition includes Thyme Leaf, Wild Cherry Bark, Cocoa Extract, Mullein Leaf Extract, and Boswellia Serrata . In particular, the composition may prevent or treat cough, specifically caused by exposure to smoke. Also described are methods of using the herbal composition.

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14-06-2012 дата публикации

Method of improving skin regeneration effect of medicinal materials by double boiling using earthenware pot

Номер: US20120148686A1
Принадлежит: Amorepacific Corp

Disclosed is a method capable of improving the skin regeneration effect of medicinal materials through double boiling using an earthenware pot. The method shows an excellent skin regeneration effect, and the extract of medicinal materials obtained therethrough can be variously applied in the fields of cosmetics, health foods or medicine.

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21-06-2012 дата публикации

Nutritional compositions comprising citrus fibers

Номер: US20120156185A1
Автор: Anat Solomon, Haim Aviv
Принадлежит: HERBAMED Ltd

The present invention provide edible compositions comprising soluble and insoluble dietary fibers at a ratio of about 1:1 ratio, having a palatable taste, useful for reducing the serum lipid content in a mammal, and further for reducing the blood glucose level, enhancing the feeling of satiety and keeping a desired body weight.

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28-06-2012 дата публикации

Chinese herbal medicine composition used for antiinflammation, detumescence and acesodyne, and preparation method and use thereof

Номер: US20120164249A1
Принадлежит: Uni President Biotech Co Ltd

A Chinese herbal medicine composition used for antiinflammation, detumescence and acesodyne, comprising first type of medicinal materials and second type of medicinal materials. The first type of medicinal materials include Rhizoma Bletillae, Cortex Cinnamomi, Radix Angelicae Formosanae, Radix Angelicae Sinensis, Paeonia Lactiflora, Rhizoma Notopterygii, Radix Linderae, Glycyrrhizae, Radix Angelicae Pubescentis, and Radix Et Rhizoma Rhei. The second type of medicinal materials is one, two or three selected from the group cosisting of Zingiber Officinale, Olibanum and Myrrha. The preparation method for the Chinese herbal medicine composition comprises the following steps: adding the first type of medicinal materials and the second type of medicinal materials into a container with organic solvent, heating, filtering, and then condensing the filtrate into an extratum.

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26-07-2012 дата публикации

Schisandrae fructus extracts for inhibition or prevention of h1n1 influenza virus infection and its application thereof

Номер: US20120189719A1
Принадлежит: NATIONAL DEFENSE MEDICAL CENTER

Disclosed are an Schisandrae fructus extract for inhibition or prevention of influenza and its application, wherein the Schisandrae fructus extract is obtained by water, methanol, or ethanol extraction process and the extract comprises compounds such as schisandrone, benzoylgomisin P, wulignan A1, epigomisin O, epiwulignan A1, and tigloylgomisin P. The extracts and purified compounds of Schisandrae fructus has anti-influenza virus H1N1 and H1N1-TR (a Tamiflu drug resistant virus strain) activities, therefore the extracts and the purified compounds of Schisandrae fructus can be applied as an inhitibory agent of a pharmaceutical composition for treatment or prevention agent for influenza infection.

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26-07-2012 дата публикации

Tangerine peel extract and its preparation and application

Номер: US20120189731A1
Принадлежит: Infinitus China Co Ltd

This invention disclosed is a tangerine peel extract with the effect of weight gain. This extract uses tangerine peel as the raw ingredient and is obtained through extraction processes using supercritical CO 2 , water, or organic solvents. The resulting extraction component contains a large quantity of flavonoids and terpenoids, which can effectively regulate the function of the spleen and stomach leading to desired weight gain. This invention also declares the preparation methods of the above mentioned tangerine peel extraction, which is simple in technique and highly effective in extraction. This invention also further declares the application of the above mentioned tangerine peel extraction in preparing healthcare food with the function of gaining weight.

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02-08-2012 дата публикации

Preparations with wood extracts of locust trees

Номер: US20120195870A1
Принадлежит: SYMRISE AG

The present invention relates primarily to the use of locust tree ( Gleditsia ) wood or heartwood extracts as anti-cellulite active substances. The present invention further relates to certain locust-tree wood extracts and mixtures containing locust-tree wood extracts and corresponding cosmetic, dermatological or pharmaceutical preparations, which are suitable in particular for the prevention and treatment of cellulite in humans.

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16-08-2012 дата публикации

Nutritional supplement to improve supplementary target protein fraction (tpf) delivery, intracellular absorption and utilization

Номер: US20120207710A1
Автор: Shawn P. Madere
Принадлежит: Individual

A nutritional supplement includes the primary ingredients: N-acetyl D-glucosamine, cracked cell wall Green Chlorella, Licorice Root Extract, and Potassium Citrate, as well as secondary ingredients: Zinc L-Carnosine, Gamma-Oryzanol and Capsaicin, that improves the bodies uptake, utilization and over-all bioavailability of exogenous target protein fractions (TPF) including but not limited to: glycoproteins, (such as glucosamine) protein isolates as amino acids, glycosaminoglycans (GAG) (including proteoglycans, and mucopolysaccharides), and polysaccharides such as hyaluronic acid (hyaluronan). The biochemical interactions of the composition improves zeta potential for TPF incorporation in the body through direct and indirect interaction with primary cellular and digestive sites of multiple species. This facilitates greater passage of target protein substrates fractions and isolates into the bloodstream, provides superior intracellular absorption and utilization thereby potentiating the therapeutic effects of TPF systemically.

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16-08-2012 дата публикации

Em-Lacquer Water Solution Mixed with Natural Component, Method for Preparing Fermented Anti-Oxidant Material Using the Same, and Method for Processing the Material

Номер: US20120208230A1
Автор: Jeong Wan Ha
Принадлежит: Individual

The present invention relates to an EM-lacquer water solution mixed with a natural component, a method for preparing a fermented anti-oxidant material using the same, and a method for processing the material. Particularly, the EM-lacquer water solution mixed with a natural component is prepared by mixing an EM-lacquer solution, which is a mixture of a crude solution of effective micro-organisms (EM) 20˜35 weight percent and a lacquer water solution 65˜80 weight percent, and at least one natural component selected from a group comprising of organic brown sugar, bay salt, mandarin orange oil, Japanese apricot concentrate, Opuntia humifusa powder, dried orange peel powder, green tea powder, sea tangle powder, rice bran, camellia oil and bean powder, on the basis of the EM-lacquer water solution 20 L. Therefore, it can be used for daily life, industry, environmental purification and the like because it is made of non-toxic materials.

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23-08-2012 дата публикации

Antibacterial Food Composition

Номер: US20120214781A1
Автор: Loic Renard
Принадлежит: Individual

The present invention relates to an antibacterial food composition comprising a Propolis extract and a Vaccinium macrocarpon cranberry extract.

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30-08-2012 дата публикации

Coconut oil-based intranasal composition and use

Номер: US20120219644A1
Принадлежит: Individual

The present invention relates to the use of coconut oil as an active agent in natural, health-promoting products, particularly for intranasal use.

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20-09-2012 дата публикации

Profiles of lipid proteins and inhibiting HMG-CoA reductase

Номер: US20120237626A9
Принадлежит: Individual

The present invention comprises methods and compositions for improving profiles of lipid proteins, reducing low-density lipoprotein levels, increasing high-density lipoprotein levels, decreasing the absorption of fatty acids across the intestinal epithelium and inhibiting HMG-CoA Reductase in living organisms utilizing Morinda citrifolia L activity in mammals, including humans.

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20-09-2012 дата публикации

In vitro anti-sickling activity of betulinic acid, oleanolic acid and their derivatives

Номер: US20120237629A1
Принадлежит: University of Kwazulu Natal

The invention provides triterpenoid compounds selected from betulinic acid, maslinic acid, oleanolic acid, esters thereof and mixtures of any two or more thereof for the treatment of sickle-cell anaemia.

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27-09-2012 дата публикации

Herbal extracts and flavor systems for oral products and methods of making the same

Номер: US20120244084A1
Принадлежит: Individual

The invention provides a method for preparing an herbal extract and a flavor system comprising an herbal extract produced by the process. The invention also provides a flavor system comprising an herbal extract comprising thymol, eugenol, carvacrol and eucalyptol. The invention further provides a flavor system comprising a thyme extract having a minimum inhibitory concentration of less than about 3%. Additionally, the invention provides an oral product comprising a flavor system.

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04-10-2012 дата публикации

Composition containing protopanaxatriol and protopanaxadiol

Номер: US20120252768A1
Принадлежит: Lion Corp

A composition including: at least one mixture selected from the group consisting of a mixture of (A) panaxatriol and (B) protopanaxatriol and a mixture of (C) panaxadiol and (D) protopanaxadiol, wherein a ratio (A)/(B) of a mass of the (A) panaxatriol to a mass of the (B) protopanaxatriol is 1 or greater, and a ratio (C)/(D) of a mass of the (C) panaxadiol to a mass of the (D) protopanaxadiol is 1 or greater.

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22-11-2012 дата публикации

Method for manufacturing aloe powder

Номер: US20120294913A1
Принадлежит: Morinaga Milk Industry Co Ltd

A technique for efficiently performing pulverization of a dried aloe gel using an air flow type mill is provided. 1) A dried aloe gel is treated by supercritical extraction, an extract is removed from the dried aloe gel to obtain an extraction residue, and then 2) the extraction residue is pulverized with an air flow type mill to produce an aloe powder.

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22-11-2012 дата публикации

Method

Номер: US20120297507A1
Принадлежит: IMPERIAL INNOVATIONS LTD

A method for producing leafy biomass from undifferentiated plant cells, the method comprising providing undifferentiated plant cells, contacting them with an agent that promotes differentiation of the cells into leafy tissue and growing the cells in a temporary liquid immersion culture system. This method of the invention may be used to produce polypeptides, and natural medicinal products, and can be used to capture carbon dioxide. A method of producing a polypeptide in plant cells in vitro comprising: providing undifferentiated plant cells containing chloroplasts that carry a transgenic nucleic acid molecule encoding the polypeptide, wherein the plant cells display homoplastomy; and propagating the cells according to the above method to produce leafy biomass containing the polypeptide.

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29-11-2012 дата публикации

Immunostimulating Agent and Method for Production Thereof

Номер: US20120301505A1
Принадлежит: Individual

The object is to provide: a safe immunomodulating agent which can be used as a pharmaceutical or a food material; a method for production of the immunomodulating agent; and a novel application of a coffee extract residue. Disclosed is an immunomodulating agent comprising a coffee extract as an active ingredient. Preferably, the coffee extract is an extract containing arabinogalactan. The immunomodulating effect of the immunomodulating agent relies on the promotion of the proliferation of an immunocompetent cell such as a macrophage. The immunocompetent cell is preferably any one selected from a macrophage like strain RAW264 or J774.1, a murine splenocyte, a murine peritoneal macrophage and a murine dendrocyte. A composition containing the immunomodulating agent can be used as a composition such as a pharmaceutical composition, a food composition and a cosmetic composition.

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29-11-2012 дата публикации

Composition comprising solanum glaucophyllum for preventing and/or treating hypocalcaemia and for stabilizing blood calcium levels

Номер: US20120301513A1
Принадлежит: HERBONIS AG

The present invention provides a pharmaceutical and/or veterinary composition comprising a retard release formulation of a Solarium glaucophyllum preparation. The composition further preferably comprises a calcium source. The composition of the invention is suitable to prevent and/or treat hypocalcaemia. Furthermore, the composition is suitable to prevent milk fever in cows. Advantageously, the composition is administered only once before calving so as to prevent the occurrence of milk fever in cows.

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29-11-2012 дата публикации

Method of assisting with digestive upsets using a confection-based delivery of peppermint oil and ginger

Номер: US20120301557A1
Автор: Dustin Garth James
Принадлежит: Enteral Health and Nutrition LLC

A confection for assisting with the relief of common digestive complaints is provided. The confection includes a carbohydrate base and an active agent infused into the carbohydrate base. The active agent includes at least one of ginger extract or peppermint oil.

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29-11-2012 дата публикации

Dietary regimens useful for mimicking caloric restrictions

Номер: US20120301559A1
Принадлежит: Individual

The invention provides dietary regimens useful mimicking caloric restriction in animals. The regimens use a first diet containing one or more dietary supplements suitable for mimicking caloric restriction when the animal is a young animal; a second diet containing one or more dietary supplements suitable for mimicking caloric restriction when the animal is an adult animal; and a third diet containing one or more dietary supplements suitable for mimicking caloric restriction when the animal is a senior animal; wherein the dietary supplements in the first diet, second diet, and third diet are not all be the same dietary supplements.

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29-11-2012 дата публикации

Composition for improving blood circulation, containing extract of lindera obtusiloba as active ingredient

Номер: US20120301562A1

Provided is a composition for improving blood circulation, comprising an extract of Lindera obtusiloba as an active ingredient, and more specifically, to a pharmaceutical composition and a health functional food for preventing and treating thrombotic disorders by improving blood circulation, comprising an extract of Lindera obtusiloba as an active ingredient. The extract of Lindera obtusiloba of the present invention and a crude purified product thereof can be obtained through extraction using various solvents such as water, ethanol, methanol, butanol, etc. Since the extract and the crude purified product have not only excellent inhibitory effect on platelet aggregation induced by various aggregation inductions in vitro, but also excellent inhibitory effect on rapid thrombus formation in vivo, they can be useful for preventing and treating diseases caused by blood circulation disorders such as thromboembolism, etc.

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06-12-2012 дата публикации

Wormwood pill containing 95% of wormwood ethyl alcohol extract that has inactivation efficacy of the h1n1 virus and the h9n2 avian influenza virus

Номер: US20120308653A1
Автор: Bongkwan Jo, Heeyoung Shim
Принадлежит: Individual

A mugwort pill containing a 95% ethanol extract of wormwood having an inactivation power with respect to a novel swine-origin influenza virus and an avian influenza virus is disclosed. In more details, the conventional mugwort pill is prepared by a hot water extraction method and has 0.8% of crude fat component; however the ethanol extract mugwort crude fat of the present invention is 11.6%, in particular the crude fat component is 14.5 times higher, and the novel swine-origin influenza virus (H1N1) can be inactivated 99.99%, and it has a good disinfection effect to an avian influenza virus (H9N2). When a mugwort pill containing a 95% ethanol extract of wormwood having an inactivation power with respect to a novel swine-origin influenza virus and an avian influenza virus is administrated to people or fowls, the people or fowls can have immunity with respect to a novel swine-origin influenza virus and an avian influenza virus.

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13-12-2012 дата публикации

Pharmaceutical composition including sunflower extract, preparative method and use thereof

Номер: US20120315332A1
Принадлежит: Individual

A pharmaceutical composition containing sunflower extract comprises the extract of total flavonoids from leaves, heads or stems of sunflower ( Helianthus annuus L.), in which the content of total flavonoids is 50-90%. Preferably, the pharmaceutical composition comprises the extract of total terpenes and/or the extract of total organic acids. The pharmaceutical composition is used as an active ingredient in manufacture of foods, functional foods or medicaments for preventing or treating hypertension.

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20-12-2012 дата публикации

Nutritional formula for managing angina pectoris

Номер: US20120321728A1
Автор: Ven Subbiah
Принадлежит: Individual

The present invention is a novel nutritional product composition, formulated to be used as medical foods for managing blood flow related problems. The formula comprises clary sage root extract highly enriched for Tanshinones L-arginine, niacin, vitamin C, Vitamin B6, vitamin B12, folate and soy isoflavones. The composition enhances the increased blood flow to the muscle mass. Tanshinone IIA is an inducer of heme oxygenase 1 and suppressor of the induction of inducible nitric oxide synthase, which could result in desirable effects on two important gaseous signaling molecules, namely carbon monoxide and nitric oxide that have significant anti-inflammatory properties.

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20-12-2012 дата публикации

(2's)-columbianetin isolated from corydalis heterocarpa and composition containing the same

Номер: US20120323022A1

The present invention relates to a compound of (2′S)-columbianetin having photo-protective effect isolated from Corydalis heterocarpa and a cosmetic composition containing the same, which has great effects on prevention and treatment in UVB-induced skin damage.

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03-01-2013 дата публикации

Herbal medicinal composition and extract thereof for inhibiting growth of cancer cells

Номер: US20130004597A1
Автор: Chen-Yu LEE
Принадлежит: Individual

The present invention relates to herbal medicinal compositions and extracts thereof for inhibiting growth of cancer cells. One of the examples described in the present invention comprises Forsythiae fructus, Menthae Herba, Gardeniae Fructus, Scutellariae Radix, Lophatheri Folium, Glycyrrhizae Radix, Rhei Rhizoma, Na 2 SO 4 , and Atractylodis Rhizoma. The residual examples are described herein.

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03-01-2013 дата публикации

Inhibition of the Survival of Gastric Cancer by Cyclohexenone Compounds from Antrodia Camphorata

Номер: US20130005826A1
Принадлежит: Golden Biotechnology Corp

The present invention relates to a novel application of a compound. The compound 4-hydroxy-2,3-dimethoxy-6-methyl-5-(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone of the invention is isolated and purified from the extracts of Antrodia camphorata, which can be applied for inhibiting the survival of gastric cancer cells and be used as a pharmaceutical composition to inhibit the gastric tumor growth.

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03-01-2013 дата публикации

Composition and method to alleviate joint pain

Номер: US20130005828A1
Принадлежит: US Nutraceuticals LLC

Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found with krill oil and/or marine oil in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.

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10-01-2013 дата публикации

Ginger Extract for Inhibiting the Fat-storage Function of Adipocytes and a Medication thereof

Номер: US20130011500A1
Принадлежит: Han Sheng Pharmtech Inc

In the present invention, a ginger extract for inhibiting the fat-storage function of adipocytes and a medication thereof is disclosed, wherein the ginger extract is obtained form Alpinia galangal and Zingiber zerumbet.

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10-01-2013 дата публикации

Anti-Fever Botanical Composition and Uses Thereof

Номер: US20130011501A1
Принадлежит: Micro Dose Life Sciences LLC

According to at least one aspect of the present invention, a botanical anti-fever composition is provided. In at least one embodiment, the botanical composition comprises a therapeutically effective amount of admixture of parts or extracts of at least one plant species from each of genus Baptista and genus Swertia . In at least one particular embodiment, the botanical composition contains Baptista Tincoria . In at least another particular embodiment, the botanical composition contains Swertia Chirata.

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10-01-2013 дата публикации

Stimulation of the synthesis of the activity of an isoform of lysyl oxidase-like loxl for stimulating the formation of elastic fibers

Номер: US20130011902A1

The invention relates to the stimulation of the synthesis and of the activity of an isoform of lysyl oxidase, and more particularly of the LOXL (lysyl oxidase-like) isoform. The invention relates notably to a method of identifying an active principle which stimulates the formation of elastic fibers. The aim of the invention is mainly to provide such a method of identification so as to provide compositions which enable stimulating the formation of elastic fibers.

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17-01-2013 дата публикации

Herbal medicinal composition and extract thereof for inhibiting growth of cancer cells

Номер: US20130017275A1
Автор: Chen-Yu LEE
Принадлежит: Individual

The present invention relates to herbal medicinal compositions and extracts thereof for inhibiting growth of cancer cells. One of the examples described in the present invention comprises Forsythiae fructus, Menthae Herba, Gardeniae Fructus, Scutellariae Radix, Lophatheri Folium, Glycyrrhizae Radix, Rhei Rhizoma, Na 2 SO 4 , and Atractylodis Rhizoma. The residual examples are described herein.

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17-01-2013 дата публикации

Composition and method for improving brain function

Номер: US20130017278A1
Автор: Arlene Keller
Принадлежит: Individual

A composition and method for improving and maintaining brain function wherein the composition comprises an effective amount of coconut oil and an effective amount of medium-chain triglycerides. The medium-chain triglycerides and coconut oil may be mixed in a ratio of between 90% medium-chain triglycerides to 10% coconut oil and 40% medium-chain triglycerides to 60% coconut oil. The method comprises administering to a person, an effective amount of coconut oil and an effective amount of medium-chain triglycerides. The composition may be administered in a food item.

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24-01-2013 дата публикации

Methods For Inhibiting Tyrosinase Using an Extract of Laminaria Saccharina

Номер: US20130022559A1
Принадлежит: Procter and Gamble Co

A method of inhibiting tyrosinase activity may involve the step of applying a composition comprising a Laminaria Saccharina extract to a substrate in need of tyrosinase inhibition. The method may further comprise a step of identifying a substrate in need of tyrosinase inhibition. The composition may be left on the substrate and/or repeatedly applied to the substrate to achieve the desired inhibition of tyrosinase activity.

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24-01-2013 дата публикации

Expression Modulator For Clock Gene Bmal

Номер: US20130022635A1
Принадлежит: Shiseido Co Ltd

The present invention provides a substance which can modulate expression of a Bmal gene effectively and with a wide range of application. Provided is an expression modulator for the Bmal gene comprising, as an active ingredient, one or more selected from the group consisting of hinoki cypress extract, chlorella extract, hop extract, Zanthoxylum extract, juniper oil, lavender oil, eucalyptus oil, olibanum, cypress oil, palmarosa oil, pineneedle oil, rose oil, ylang-ylang oil, elemi oil, petitgrain oil, pepper oil, thyme oil and chamomile oil.

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31-01-2013 дата публикации

Use of black soybean hull extracts in manufacture of products for preventing and treating osteoarthritis

Номер: US20130030046A1

The application relates to a use of black soybean hull extracts in the manufacture of foods, health care products and medicaments. The black soybean hull extracts can be added to foods or drinks, and also can be made into all kinds of oral health care products and oral medicaments used by conventional methods of preparing traditional Chinese medicine preparations. The products can significantly improve symptoms of osteoarthritis, and also can stabilize or even reverse the degradation of cartilage of osteoarthritis.

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07-02-2013 дата публикации

Method of using pomegranate extracts for increasing prostate specific antigen doubling time

Номер: US20130035300A1
Автор: Harley Liker
Принадлежит: Individual

A method of increasing a prostate specific antigen (PSA) doubling time in treating a patient. A subject with rising serum PSA is selected. A composition is administered to the subject comprising a therapeutically effective amount of a pomegranate extract comprising a higher content of high molecular weight polyphenol compared to pomegranate juice from arils. The therapeutically effective amount increases a prostate specific antigen doubting time. The pomegranate extract is formed from an insoluble byproduct component obtained by placing pomegranate solids in an aqueous solution, heating the aqueous solution to between about 60° F. to about 210° F., adding at least one enzyme to the aqueous solution, and removing residual insoluble solid materials from the aqueous solution.

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21-02-2013 дата публикации

Composition for promoting the activity of peroxisome proliferator-activated receptor-delta

Номер: US20130045289A1
Принадлежит: Amorepacific Corp

Disclosed is a composition for promoting the activity of peroxisome proliferator-activated receptor-δ (PPAR-δ), which contains Artemisia vulgaris extracts or Artemisia capillaris extracts as active ingredients. The composition is effective in strengthening muscles, improving endurance and memory, and preventing and alleviating the symptoms of dementia or Parkinson's disease.

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28-02-2013 дата публикации

Warming Inch Loss Delivery System

Номер: US20130052275A1
Автор: Michelle Ward
Принадлежит: Individual

This invention is a topical treatment for the skin, used for skin enhancement, firming, smoothing, refining and to reduce the appearance of cellulite; that has a self-warming or thermogenic effect comprised of a base combination of warming herbs (Ayurvedic), being any herbs that create a warming effect, combined with dietary minerals that can be blended together in any ratio.

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28-02-2013 дата публикации

Palm kernel oil-based intranasal composition and use

Номер: US20130052284A1
Принадлежит: Individual

The present invention relates to the use of palm kernel oil as an active agent in natural, health-promoting products, particularly for intranasal use.

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28-02-2013 дата публикации

Composition for treatment of aesthenopia

Номер: US20130052286A1
Принадлежит: Nihon Pharmaceutical Co Ltd

This is to provide a novel medicine and a food and a drink composition for treating aesthenopia excellent in improved effect of aesthenopia. The composition for the treatment of aesthenopia comprises chondroitin sulfate or a salt thereof.

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14-03-2013 дата публикации

Biologically Active Oils

Номер: US20130064808A1
Автор: Turner Athol Gillies
Принадлежит:

A process for the production of fats or oils and their extracts containing biologically active chemical compounds from a lipid substrate, the process comprising: a) inoculation of a lipid substrate with fungally derived lipolytic enzymes; b) incubating the inoculated substrate for a period of between about 7-120 days at a temperature of between about 4-35° C., at a humidity of between about 75-100%, and c) processing said substrate mixture to obtain a biologically active fat or oil. 1. A solid state process for the production of fats or oils and/or their extracts containing biologically-active chemical compounds from a lipid substrate , the process comprising:a) Inoculation of a lipid substrate with a fungal mixture having enzymatic activity, said fungal mixture being derived from said substrate;b) Incubating the inoculated substrate for a period of between about 7-120 days at a temperature of between about 4-35° C., at a humidity of between about 75-100%, such that said fungal mixture metabolises/transforms the lipid substrate into said fats or oils and/or their extracts containing biologically-active chemical compounds; andc) Processing said incubated substrate mixture to obtain a biologically active fat or oil.2. A solid state process for the production of fats or oils and/or their extracts containing biologically-active chemical compounds from a lipid substrate , the process comprising:a) Incubating the lipid substrate without any inoculation of a fungal mixture, for a period of between about 7-120 days at a temperature of between about 4-35° C. at a humidity of between about 75-100%, such that the lipid substrate transforms into said fats or oils and/or their extracts containing biologically-active chemical compounds; andb) Processing said incubated substrate mixture to obtain a biologically active fat or oil.3. The process according to claim 1 , wherein in step b) claim 1 , the period of incubation is between about 7 to 56 days claim 1 , at a temperature of ...

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21-03-2013 дата публикации

METHODS AND COMPOSITIONS FOR BONE AND CARTILAGE REPAIR

Номер: US20130071359A1
Принадлежит: CIMTECH Pty Limited

Biologically active extract of L. and compositions comprising the extract are described. The invention also provides therapeutic uses of the extract and compositions, in particular for promoting healing of bone and cartilage injuries, and the promotion of bone and cartilage formation. 141-. (canceled)42Hibiscus tiliaceus. A biologically active extract of L. , wherein the extract is prepared using and/or comprises a plant based oil.43. An extract of claim 42 , wherein the extract is derived from one or more of a bark claim 42 , leaf claim 42 , vine claim 42 , bean claim 42 , husk or nut.44Hibiscus tiliaceus. An extract of claim 42 , wherein the L. extract is derived from bark.45. An extract of claim 42 , wherein the plant based oil is derived from plant seeds or fruit.46Cocos nucifera.. An extract of claim 42 , wherein the plant based oil is derived from47Cocos nuciferaCocos nuciferaCocos nuciferaCocos nuciferaCocos nucifera. An extract of claim 46 , wherein the oil is virgin oil claim 46 , refined oil claim 46 , hydrogenated oil or fractionated oil.48. A composition comprising an extract according to claim 42 , and one or more pharmaceutically acceptable carriers claim 42 , diluents and/or excipients for the treatment of bone or cartilage injury and/or the promotion of bone or cartilage formation claim 42 , repair or regeneration.49. A composition of claim 48 , wherein the composition is administered topically or parenterally.50. A method for promoting the formation claim 48 , repair or regeneration of bone or cartilage in a subject claim 48 , the method comprising administering to the subject in need thereof an effective amount of{'i': 'Hibiscus tiliaceus', '(a) a composition comprising a biologically active extract of L., wherein the extract is prepared using and/or comprises a plant based oil, and one or more pharmaceutically acceptable carriers, diluents and/or excipients, or'}(b) osteoblasts, osteoblastic progenitor cells, or bone segments or fragments cultured ...

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21-03-2013 дата публикации

Oral Formulations For Promoting Cellular Purification

Номер: US20130071369A1
Принадлежит: NSE Products, Inc.

An oral formulation includes a plurality of agents that promote cellular detoxification. Agents can be included that modulate expression of Nrf2-associated genes upon ingestion of the oral formulation by a subject, wherein the Nrf2-associated genes include at least one gene encoding intrinsic antioxidants, and at least one gene encoding cellular detoxifiers. In addition, at least one of the plurality of agents attenuates inflammation. 1. An oral formulation comprising a plurality of agents that modulate expression of Nrf2-associated genes upon ingestion of the oral formulation by a subject , wherein the Nrf2-associated genes include at least one gene encoding intrinsic antioxidants , and at least one gene encoding cellular detoxifiers , and wherein at least one of the plurality of agents attenuates inflammation.2. The oral formulation of claim 1 , wherein the Nrf2-associated genes are selected from the group consisting of NFE2L2 claim 1 , GCLM claim 1 , GCLC claim 1 , GSR claim 1 , GSTA1 claim 1 , GPX1 claim 1 , GPX4 claim 1 , HMOX1 claim 1 , NQO1 claim 1 , SRXN1 claim 1 , SQSTM1 claim 1 , SOD1 claim 1 , UGT1A6 claim 1 , NOS2 claim 1 , NOS3 claim 1 , and PTGS2.3. The oral formulation of claim 2 , wherein at least one of the plurality of agents substantially reverses an age-related change in expression of at least one of the Nrf2-associated genes.4. The oral formulation of claim 1 , wherein the plurality of agents combine to modulate expression of at least five Nrf2-associated genes.5. The oral formulation of claim 1 , wherein at least one of the plurality of agents upregulates a gene encoding intrinsic antioxidants.6. The oral formulation of claim 1 , wherein at least one of the plurality of agents upregulates a gene encoding cellular detoxifiers.7. The oral formulation of claim 1 , wherein at least one of the plurality of agents stimulates autophagy in a tissue of the subject.8. The oral formulation of claim 1 , wherein the plurality of agents include at least two ...

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21-03-2013 дата публикации

BATHING COMPOSITION AND METHOD FOR PREPARING SAME

Номер: US20130071376A1
Автор: Lee Dong-Joo
Принадлежит:

The present invention relates to a composition for bath additives characterized in that the composition is obtained by a process comprising subjecting herbal materials comprising 10˜25% by weight of , 10˜20% by weight of , 5˜15% by weight of , 1˜20% by weight of , 1˜15% by weight of , 1˜15% by weight of , 1˜15% by weight of -, 1˜10% by weight of and 1˜10% by weight of , based on the total dry weight of the above herb materials, to liquid phase fermentation with which is anaerobic, to obtain a culture, separating sludge from the resulting culture, drying, sterilizing and pulverizing the culture to give a pulverized sludge, and a process for preparing the same. 1Zizania latifolia,Artemisia capillaries,Houttuynia cordata,Saururus chinensis,Leonurus sibiricus,Angelica gigas,Coix lachrymajobi,Plantago asiaticaRhododendron brachycarpumBacillus subtilis. A composition for bath additives obtained by subjecting medicinal herb materials comprising 10˜25% by weight of 10˜20% by weight of 5˜15% by weight of 1˜20% by weight of 1˜15% by weight of 1˜15% by weight of 1˜15% by weight of -1˜10% by weight of and 1˜10% by weight of , based on the total dry weight of the above herb materials , to liquid phase fermentation with which is anaerobic , to obtain a culture , separating sludge from the resulting culture , drying , sterilizing and pulverizing the culture to give a pulverized sludge.2. The composition for bath additives as claimed in wherein the liquid phase fermentation is performed at a temperature of 30˜40° C. for 50˜100 days.3Achillea sibirica,Rumex crispus, andLithospermum erythrorhizon.. The composition for bath additives as claimed in wherein the above medicinal herb materials further comprise 1˜10% by weight of Saliconia herbacea claim 1 , 7˜17% by weight of 5˜15% by weight of 1˜10% by weight of4. A composition for bath additives characterized in that the composition is obtained by a process comprising:{'i': Zizania latifolia,', 'Artemisia capillaries,', 'Houttuynia ...

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21-03-2013 дата публикации

COMPOSITION FOR INCREASING MILK PRODUCTION CONTAINING ARTEMISIA CAPILLARIS

Номер: US20130071377A1
Принадлежит: RNL BIO CO., LTD

The present invention relates to a composition for increasing the milk production of livestock, containing as an active ingredient. More specifically, relates to a composition and a feed additive for increasing the milk production of cows, containing as an active ingredient, and a composition and a feed additive for reducing the number of somatic cells in livestock milk, containing as an active ingredient. The composition can increase milk production of animals, and, in addition, can reduce the number of somatic cells in milk being produces, thus enabling production of good quality milk. 1Artemisia capillaris. A method for increasing milk production of livestock , said method comprises administering a feed additive containing fermented as an active ingredient to livestock.2Artemisia capillaris. A method for increasing milk production of livestock , said method comprises administering a composition containing fermented as an active ingredient to livestock.3Artemisia capillaris. A method for promoting human breast milk production , said method comprises administering a composition containing fermented as an active ingredient to human.4Artemisia capillaris. A method for reducing somatic cells in livestock milk , said method comprises administering a composition containing as an active ingredient.5Artemisia capillarisArtemisia capillarisArtemisia capillarisArtemisia capillaris.. The method for reducing somatic cells in livestock milk according to claim 4 , wherein said is selected from the group consisting of powder claim 4 , extract and fermented6Artemisia capillaris. A method for reducing somatic cells in livestock milk claim 4 , said method comprises administering a feed additive containing as an active ingredient.7Artemisia capillarisArtemisia capillarisArtemisia capillarisArtemisia capillaris.. The method for reducing somatic cells in livestock milk according to claim 6 , wherein said is selected from the group consisting of powder claim 6 , extract and fermented ...

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21-03-2013 дата публикации

TOPICAL PHARMACEUTICAL OR COSMETIC COMPOSITION USEFUL FOR THE TREATMENT OF DISEASES OR CONDITIONS THAT TRANSCUR THROUGH A DEFICIT OF MATURATION OF THE CORNIFIED ENVELOPE

Номер: US20130071426A1
Принадлежит: LABORATORIOS LETI, S.L.

It comprises a combination of glycerin, niacinamide, and an extract of , to topical pharmaceutical or cosmetic compositions containing them, processes for their preparations, as well as their pharmaceutical use in the prophylaxis and/or treatment of disease or conditions that transcur through a deficit of maturation of the cornified envelope, and their cosmetical use as a skin care agent, skin barrier recovery agent, and moisturizer. 1. A combination comprisingglycerin,niacinamide, and{'i': 'Fucus Serratus.', 'an extract of'}2Fucus SerratusFucus Serratus. The combination according to claim 1 , wherein the extract of is a glycolic extract claim 1 , wherein when the glycolic extract of is a glycerol extract claim 1 , and the extract contains a part or the total amount of the glycerin of the combination.3Fucus Serratus. The combination according to claim 2 , wherein the glycolic extract of is a glycerol extract.4. The combination according to claim 3 , wherein the glycolic extract contains the total amount of the glycerin of the combination.5. The combination according to claim 3 , wherein the glycolic extract contains a part of the amount of the glycerin of the combination.6Fucus Serratus. The combination according to claim 2 , wherein the weight ratio (weight/weight/weight) between glycerin claim 2 , niacinamide claim 2 , and the glycolic extract of is comprised between 1.5:1:0.1 and 1.5:1:0.5.7Fucus Serratus. The combination according to claim 6 , wherein the weight ratio (weight/weight/weight) between glycerin claim 6 , niacinamide claim 6 , and the glycolic extract of is 1.5:1.0:0.2.8. A topical pharmaceutical or cosmetic composition which comprises an effective amount of the combination as defined in claim 1 , together with one or more appropriate topical pharmaceutically or cosmetically acceptable excipients or carriers.9. The topical pharmaceutical or cosmetic composition according to claim 8 , wherein the one or more appropriate topical pharmaceutically or ...

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21-03-2013 дата публикации

KIT OF PARTS FOR TREATING AND/OR PREVENTING CUTANEOUS ULCERS

Номер: US20130071427A1
Автор: Logi Roberto
Принадлежит:

The present invention regards a kit of parts for treating and/or preventing cutaneous ulcers, preferably chronic ulcers, such as for example decubitus ulcers, even more preferably trophic ulcers of the lower limbs, and for treating and/or preventing cutaneous ulcers caused by the virus, preferably lip ulcers, or cutaneous ulcers that occur in form of (shingles), comprising a resin extract and essential oil. 1Croton lechleriMelaleuca alternifolia. Kit of parts for treating and/or preventing cutaneous ulcers , comprising a resin extract and oil.2Calendula officinalis,Hamamelis virginiana,Hypericum perforatum. Kit of parts according to claim 1 , further comprising one or more elasticisers claim 1 , preferably selected from among an ointment based on and/or an ointment or cream based on and/or oil.3Herpes simplexHerpes zoster.. Kit of parts according to claim 1 , wherein the cutaneous ulcers are chronic ulcers claim 1 , preferably decubitus ulcers and/or trophic ulcers of the lower limbs or wherein the cutaneous ulcers are ulcers caused by the virus claim 1 , preferably lip ulcers claim 1 , or cutaneous ulcers that occur in form of4Croton lechleriCroton LechleriCroton lechleriCroton lechleriMelaleuca alternifolia. Kit of parts according to claim 1 , wherein the resin extract is a liquid solution of resinous latex claim 1 , 100% of plant origin claim 1 , of the plant at least 5 years old and even more preferably it is a liquid solution of pure resin extracted in 10% of alcohol or it is a liquid solution of pure resin in 1:10 dilution in glycerol hydroalcoholic solution claim 1 , and/or wherein the oil used is a 100% essential oil.5Calendula officinalisCalendula officinalis,Calendula officinalisHamamelis virginianaHamamelis virginianaHypericum perforatum. Kit of parts according to claim 2 , wherein the ointment based on wherein the calendula officinalis is a hydroalcoholic extract comprised between 5 and 15% of preferably a hydroalcoholic extract at 10% of and/or wherein ...

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21-03-2013 дата публикации

Fenugreek Seed Extract to Lower Blood Cholesterol

Номер: US20130071470A1
Принадлежит:

A method of lowering blood cholesterol in a non-diabetic patient by at least 30% is described. The method involves orally administering for 30 consecutive days a fenugreek seed extract composition. Various methods of preparation and various formulations are described. Physiologically effective pharmaceutical compositions and beverages containing fenugreek seed extracts and other active components are also disclosed. 1Trigonella foenum graecum. A composition consisting essentially of fenugreek () seed extract.2. The composition of claim 1 , wherein the composition is selected from the group consisting of a pill claim 1 , capsule claim 1 , granules claim 1 , microparticles claim 1 , nanoparticles and liposomes.3. The composition of claim 1 , wherein the composition is formulated for oral delivery in an oral dosage form.4. The composition of claim 1 , wherein the composition optionally includes an agent selected from the group consisting of a pharmaceutically acceptable excipient claim 1 , lubricant claim 1 , binder claim 1 , glidant claim 1 , filler claim 1 , flavoring agent claim 1 , masking agent claim 1 , vitamin claim 1 , mineral claim 1 , a carrier and mixtures thereof.5. The composition of claim 3 , wherein the composition is in oral dosage form in single dosage.6. The composition of claim 5 , wherein the composition is oral dosage form in a single dose enteric coated formulation.7. The composition of claim 1 , wherein the oral dosage form is a liquid oral formulation.8. The composition of claim 7 , wherein the liquid oral formulation is a liposomal formulation.9. The composition of claim 3 , wherein the oral dosage from contains a plurality of therapeutic nanoparticles.10. The composition of claim 1 , wherein the extract is contained in a package with instructions for use. This application is a continuation application of U.S. application Ser. No. 11/030,886 filed Jan. 10, 2005, now pending; which claims the benefit under 35 USC §119(e) to U.S. Application Ser. ...

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21-03-2013 дата публикации

ORGANIC LUBRICANT

Номер: US20130071485A1
Принадлежит:

A vaginal lubricant of primarily organic materials has excellent properties for relieving vaginal dryness. 1. A vaginal lubricant , comprising:a base material of oila combination of other ingredients effective to provide a viscosity below 2000 cP at a shear rate of 100 inverse seconds at a temperature at least 21 C.2. A lubricant as in claim 1 , wherein the base material is a non-synthetic oil.3. A lubricant as in claim 1 , wherein the base material includes sunflower oil.4. A lubricant as in claim 2 , wherein the base material includes sunflower oil.5. A lubricant as in claim 1 , wherein the base material includes beeswax.6. A lubricant as in claim 2 , wherein the base material includes beeswax.7. A lubricant as in claim 3 , wherein the base material includes beeswax.8. A lubricant as in claim 4 , wherein the base material includes beeswax.9. A lubricant as in claim 1 , wherein the lubricant is shear-thinning.10. A lubricant as in claim 2 , wherein the lubricant is shear-thinning.11. A lubricant as in claim 3 , wherein the lubricant is shear-thinning.12. A lubricant as in claim 4 , wherein the lubricant is shear-thinning.13. A lubricant as in claim 5 , wherein the lubricant is shear-thinning.14. A lubricant as in claim 6 , wherein the lubricant is shear-thinning.15. A lubricant as in claim 7 , wherein the lubricant is shear-thinning.16. A lubricant as in claim 8 , wherein the lubricant is shear-thinning. This application claims the benefit of U.S. Provisional Application 61/475,621, filed Apr. 14, 2011.Vaginal dryness is a common concern for which remedies are known, including vaginal lubricants. Dryness is a common following menopause in women and also after childbirth and may result from diseases and/or treatments thereof. Vaginal dryness can negatively impact the psychological and physical health of women.In recent years, consumers have become increasingly concerned about the safety of synthetic materials that are consumed or used on the body. There is a growing ...

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21-03-2013 дата публикации

COMPOSITION FOR TREATING INFLAMMATORY, ALLERGIC OR ASTHMA DISEASES, CONTAINING PAPRIKA EXTRACTS

Номер: US20130071499A1

The present invention relates to a composition containing a paprika extract as an active ingredient, and more particularly to a pharmaceutical composition or health functional food for preventing or treating inflammatory, allergic or asthma disease, which contains a paprika extract. Particularly, paprika is a natural food which is readily available to anyone, and thus does not cause adverse effects even when it is taken for a long period of time. 1. A pharmaceutical composition for preventing or treating inflammatory , allergic or asthma disease , which contains a paprika extract as an active ingredient.2. The pharmaceutical composition of claim 1 , wherein the extract is a crude extract claim 1 , polar solvent-soluble extract or non-polar solvent-soluble extract of paprika.3. The pharmaceutical composition of claim 2 , wherein the crude extract is an extract solubilized in a solvent selected from among water claim 2 , including purified water claim 2 , methanol claim 2 , ethanol claim 2 , butanol claim 2 , and mixed solvents thereof.4. The pharmaceutical composition of claim 2 , wherein the polar solvent-soluble extract comprises an extract solubilized in a solvent selected from among water claim 2 , ethanol claim 2 , butanol claim 2 , and mixed solvents thereof.5. The pharmaceutical composition of claim 2 , wherein the non-polar solvent-soluble extract comprises an extract solubilized in hexane claim 2 , chloroform claim 2 , dichloromethane or ethyl acetate.6. The pharmaceutical composition of claim 1 , wherein the inflammatory claim 1 , allergic or asthma disease is one or more diseases selected from the group consisting of acute inflammation claim 1 , chronic inflammation claim 1 , bronchitis claim 1 , bronchial asthma claim 1 , allergic nasitis claim 1 , allergic asthma claim 1 , allergic dermatitis claim 1 , and atopy.7. The pharmaceutical composition of claim 1 , wherein the content of the paprika extract in the composition is 0.1-50 wt % based on the total ...

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21-03-2013 дата публикации

EXTRACT OF STEWARTIA KOREANA AND USE THEREOF

Номер: US20130071501A1
Принадлежит: RNA, INC.

The present invention relates to an extract of and use thereof More particularly, it relates to an extract of which is extracted with any one selected from the group consisting of water, a Clow alcohol, a polar solvent, a non-polar solvent and a mixture thereof, and a pharmaceutical composition for promoting angiogenesis or tissue regeneration and a cosmetic for improving wrinkles comprising the same as an effective ingredient. The extract of promotes migration and multiplication of endothelial cell and shows excellent effect in angiogenesis and wound healing and is useful in treatment or prevention of diseases which requires angiogenesis for healing of wounded and frostbitten region, wound healing after surgical operation, and treatment and prevention of gastric ulcer, ischaemic heart diseases and hair loss. Also, the extract shows the dermal tissue regenerating effect and is useful as a cosmetic for improving wrinkles 18.-. (canceled)9Stewartia koreana. A method for promoting angiogenesis in a subject in need thereof , the method comprising administering an extract of to the subject.10Stewartia koreana. The method for promoting angiogenesis according to claim 9 , wherein the extract of is extracted with any one solvent selected from the group consisting of water claim 9 , a C1-4 low alcohol claim 9 , a polar solvent claim 9 , a non-polar solvent claim 9 , and a mixture thereof.11Stewartia koreana. The method for promoting angiogenesis according to claim 9 , wherein the extract of is prepared by the following steps:{'i': 'Stewartia koreana', '(a) adding leaves of in any one solvent selected from the group consisting of water, a C1-4 low alcohol, a polar solvent, a non-polar solvent, and a mixture thereof and performing extraction under reflux at about 40 to about 80° C. while stirring;'}(b) isolating a filtrate by filtration of the extract; and(c) obtaining a powder by concentrating the filtrate at reduced pressure.12. The method for promoting angiogenesis ...

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21-03-2013 дата публикации

COMPOSITIONS FOR SKIN DISEASE OR DISORDERS

Номер: US20130071502A1
Принадлежит: BAYER CONSUMER CARE AG

Medicaments or cosmetic compositions for the treatment or alleviation of skin or mucous membrane diseases or disorders related to an enhanced level of anti-microbial peptides or proteins comprising plant extracts, which may comprise polyphenols. 16-. (canceled)7Tambourissa. A method for treating skin disorders or mucous membrane disorders associated with conditions selected from the group consisting of rosacea , acne , couperosis , erythrosis , telangiectasia , herpes , mouth infections , vaginal infections , sebaceous microbial infections , baby rash , dandruff , skin redness , skin blotchiness , atopic dermatitis , psoriasis , acanthosis , solar erythemas , after shave irritation , and itching comprising the step of administering a topical composition comprising plant extract to a patient in need thereof.8. (canceled)9TambourissaTambourissa trichophylla, Tambourissa microphylla, Tambourissa religiosaTambourissa capuronii.. The method of claim 7 , wherein the plant extract is an extract of or10TambourissaTambourissa trichophylla.. The method of claim 7 , wherein the plant extract is an extract of11Tambourissa. The method of claim 7 , wherein the topical composition comprises from about 0.01% to about 10% by weight of the plant extract. This invention relates to medicaments and cosmetic compositions comprising plant extracts that in turn comprise polyphenols for the treatment or alleviation of skin or mucous membrane diseases or disorders related to an enhanced level of anti-microbial peptides or proteins. This invention also relates to processes for preparing a plant extract, the extract itself, and uses of the extract.The genus belongs to the Monimiaceae family and comprises about 43 species found throughout the western islands of the Indian Ocean, such as Madagascar, Comoros and the Mascarenes islands (Mauritius and Reunion). The various species tend to show endemic specificity as most of them are localized in only one island and in only one habitat.(Baker) ...

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21-03-2013 дата публикации

PHARMACEUTICAL COMPOSITIONS USEFUL FOR PREVENTING AND TREATING CANCER

Номер: US20130072463A1
Принадлежит: MITOTECH SA

Disclosed is a method of treating a cancer on a mammal, comprising administering to the mammal in need thereof a therapeutically effective amount of a compound 4. The method of claim 1 , wherein the compound of Structure (I) is SkQR1 claim 1 , SkQB1 claim 1 , or SkQBP1.5. The method of claim 1 , wherein the pharmaceutical composition is administered with another anti-cancer therapeutic.6. The method of claim 1 , wherein the pharmaceutical composition is a solution and is orally administered.7. The method of claim 1 , wherein the pharmaceutical composition is a solution and is parenterally administered.8. The method of claim 6 , wherein the pharmaceutical composition is an ointment claim 6 , bandage claim 6 , or film and is transdermally administered.9. The method of claim 7 , wherein the cancer is a Ras-related metastatic cancer. This application is a continuation-in-part of U.S. patent application Ser. No. 12/524,961, entitled “PHARMACEUTICAL COMPOSITIONS USEFUL FOR PREVENTING AND TREATING ONCOLOGICAL DISEASES,” filed on Feb. 16, 2010, which is a National Phase filing of International Patent Application No. PCT/RU2007/000044, filed on Jan. 29, 2007. The entirety of the aforementioned applications is incorporated by reference herein.The invention relates to pharmacology, medicine, and oncology, and in particular, to prevention and treatment of cancer using mitochondrially-targeted pharmaceutical compositions.Although there are many different anti-tumoral preparations used in clinical practice, their efficiency is in most cases insufficient and the range of diseases sensitive to such therapy is limited. Thus, new, more active preparations, and the development of such compositions which are effective in treating and preventing tumors with primary and gained resistance, remains of current interest.WO2006005759 reports on mitochondrially-targeted antioxidants application for ontological diseases therapy. This patent states that treatment of mice with tumor xenografts ( ...

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21-03-2013 дата публикации

DIETARY SUPPLEMENTS CONTAINING EXTRACTS OF CINNAMON AND METHODS OF USING SAME TO PROMOTE ENHANCED SIRTUIN, CELL AND TELOMERE INTEGRITY

Номер: US20130072574A1

A dietary supplement composition is provided for enhancing the expression of a sirtuin gene or protein. An inventive supplement composition includes at least one cinnamon extract containing at least 0.5% doubly linked Type-A polymers by dry weight. The cinnamon extract is derived from the or plant. In some embodiments, the cinnamon extract is present at approximately 20%-50% of the dry weight of the composition. A vitamin, weight loss agent, or antioxidant is optionally provided in the composition. The dietary supplement composition is administered orally to promote expression or enhanced expression of a sirtuin gene or protein. 140-. (canceled)41. A process of increasing expression of a gene encoding a sirtuin in a subject comprising:administering to a subject a composition comprising at least 0.5 percent Type-A polymers by weight, andincreasing expression of a gene encoding a sirtuin in said subject by said step of administering.42. The process of claim 41 , wherein said composition further comprises one or more vitamins claim 41 , antioxidants claim 41 , sirtuin enhancers claim 41 , or combinations thereof.43. The process of wherein said Type-A polymers comprise single and doubly linked Type-A polymers.44. The process of wherein the composition is administered orally.45. The process of wherein said vitamin is vitamin A claim 42 , vitamin B claim 42 , vitamin C claim 42 , vitamin D claim 42 , vitamin E claim 42 , or vitamin K.46. The process of wherein said antioxidant is alpha lipoic acid claim 42 , acai claim 42 , astazanthin claim 42 , wolfberry claim 42 , glutathione claim 42 , or super oxide dismutase.47. The process of wherein the sirtuin enhancer is resveratrol or polygonum.48. The process of wherein said composition is administered daily for a period of twelve weeks or more.49. The process of further comprising quantifying the expression of a sirtuin gene in said subject subsequent to said administering.50. The process of further comprising quantifying the ...

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28-03-2013 дата публикации

FUNGICIDAL COMPOUNDS AND METHODS OF THEIR USE

Номер: US20130078272A1
Принадлежит: AUCKLAND UNISERVICES LIMITED

Antifungal compounds, an antifungal compound extracted from , also known as , methods of producing the antifungal compounds, isolates and compositions comprising the antifungal compounds, and methods of using the antifungal compounds. 137-. (canceled)38Epicoccum purpurascens. A biologically pure culture of strain SVB-F1 on deposit at the National Measurement Institute , Australia (NMI) under accession number V10/000331 , deposited 18 Mar. 2010 , or a culture having the identifying characteristics thereof , or a culture extract or isolate obtained therefrom.40. The compound of wherein Ris selected from or is substituted with alkylcarbonylalkyl claim 39 , alkylcarbonyloxyalkyl claim 39 , alkyloxyalkyl claim 39 , alkylsulfonyl claim 39 , alkylsulfinyl claim 39 , alkylthioalkyl claim 39 , hydroxyalkyl claim 39 , mono-or di(alkyl)aminoalkyl claim 39 , or wherein Ris hydrogen claim 39 , hydroxyl claim 39 , or a Cto Calkyl or alkoxy group optionally comprising one or more double bonds claim 39 , and optionally substituted with one or more groups selected from lower alkyl claim 39 , lower alkenyl claim 39 , lower alkoxy claim 39 , hydroxyl and carboxyl claim 39 , or wherein Ris a Cto Calkyl or alkoxy group comprising one or more double bonds claim 39 , and substituted with one or more groups selected from lower alkyl claim 39 , lower alkenyl claim 39 , lower alkoxy claim 39 , hydroxyl and carboxyl.41. The compound of wherein R claim 39 , R claim 39 , R claim 39 , and Rare independently selected from hydrogen claim 39 , alkyl claim 39 , substituted alkyl claim 39 , alkoxy claim 39 , substituted alkoxy claim 39 , halogen claim 39 , methyl claim 39 , methoxy and hydroxyl.44. The compound of wherein R claim 43 , R claim 43 , R claim 43 , and Rare independently selected from hydrogen claim 43 , alkyl claim 43 , substituted alkyl claim 43 , alkoxy claim 43 , substituted alkoxy claim 43 , halogen claim 43 , methyl claim 43 , methoxy and hydroxyl.45. The compound of wherein each ...

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28-03-2013 дата публикации

THERAPEUTIC COMPOSITION PRODUCED USING CAMELLIA SINENSIS LEAVES AND HYDROGEN PEROXIDE

Номер: US20130078322A1
Автор: Huang Alexander L., Wu Gin
Принадлежит: LiveLeaf, Inc.

Methods of and compositions for producing and using plant-based materials are provided. The methods include using biopolymers or their synthetic equivalents combined with a stable source of reactive oxygen species that when applied to or combined with a separate source of oxido-reducing enzyme or catalyst will cause the formation of an activated biopolymer with increased protein binding affinity and microbial control activities. 1Camellia sinensisCamellia sinensis. An antibacterial composition consisting of a product prepared by combining leaves with water , heating at 80° C. to 150° C. to substantially denature enzymes endogenous to the leaves , and adding from 1% to less than 10% of hydrogen peroxide after the combining and heating.2. A multi-component , antibacterial composition consisting of a product prepared by a process having the steps of{'i': Camellia sinensis', 'Camellia sinensis;, '(i) combining with water to create a first formulation, the creating including heating at 80° C. to 150° C. to substantially denature enzymes endogenous to the'}(ii) combining pomegranate rind with water to create a second formulation, the creating including heating at 80° C. to 150° C. to substantially denature enzymes endogenous to the pomegranate rind;(iii) adding from 1% to less than 10% of hydrogen peroxide to the first formulation and the second formulation after the combining and heating, and,(iv) combining the first formulation with the second formulation.3. A dry form of the antibacterial composition of .4. A dry form of the antibacterial composition of .5. The antibacterial composition composition of claim 1 , wherein the composition endogenously contains a component selected from the group consisting of a tannin claim 1 , a lignin claim 1 , a flavonoid claim 1 , a hydroxycoumarin and an alkaloid.6. The antibacterial composition composition of claim 2 , wherein the composition endogenously contains a component selected from the group consisting of a tannin claim 2 , a ...

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28-03-2013 дата публикации

ADAPTOGENIC ACTIVITY OF LABISIA PUMILA EXTRACT

Номер: US20130078323A1
Принадлежит: HOLISTA BIOTECH SDN. BHD.

The present invention provides a process of extracting the leaves of with water into a free flowing powder using accelerated solvent system and drying. The invention also relates to the immunopotentiating effects of the extract against stress. The extract has effects on fatigue, hypoxia time, potentiation of swimming endurance, bod weight, weight of the thymus and spleen and levels of CD244+ NK cells, CD4+ and CD8+ T cells, expression of ThI cytokines IL-2 and IFN-gamma, corticosterone, glutathione, alanine aminotransferase and lipid peroxidation levels. 1Labisia pumila. A process of extracting the leaves of with water into a free flowing powder using accelerated solvent system and drying.2Labisia pumila. The process as claimed in claim 1 , wherein the aqueous leaf extract is administered systemically and orally.3Labisia pumila. The process as claimed in claim 1 , wherein adaptogen activity of the aqueous leaf extract provides anti-fatigue effect with maximum effect at 100 mg/kg p.o.4Labisia pumila. The process as claimed in claim 1 , wherein adaptogen activity of the aqueous leaf extract provides enhancement in the Hypoxia time.5Labisia pumila. The process as claimed in claim 1 , wherein adaptogen activity of the aqueous leaf extract provides higher potentiation in swimming endurance.6Labisia pumila. The process as claimed in claim 1 , wherein adaptogen activity of the aqueous leaf extract provides recovery of restraint stress induced depletion of CD244+ NK cells.7Labisia pumila. The process as claimed in claim 6 , wherein adaptogen activity of the aqueous leaf extract provides recovery in the restraint stress induced depleted CD4+ and CD8+ T cell population.8Labisia pumila. The process as claimed in claim 7 , wherein adaptogen activity of the aqueous leaf extract provides increased expression of Th1 cytokines IL-2 and IFN-gamma in restraint stress induced experimental animals.9Labisia pumila. The process as claimed in claim 1 , wherein adaptogen activity of the ...

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28-03-2013 дата публикации

TREATMENT OF CARTILAGE RESORPTION

Номер: US20130079295A1
Принадлежит: NORDIC BIOSCIENCE A/S

Excessive articular cartilage degradation is treated or prevented by administration to a mammal such as a human (Kudzu) root or an extract thereof. 1Pueraria lobata. A composition for the treatment by therapy or prophylaxis of excessive articular cartilage degradation comprising root or extracted mixture of active components thereof formulated for administration to a mammal.2. The composition as claimed in claim 1 , which is for the treatment by therapy of excessive articular cartilage degradation in the absence of joint inflammation.3. The composition as claimed in claim 1 , formulated for pharmaceutical administration or for use as a food ingredient or food supplement.4. The composition as claimed in claim 1 , wherein said composition comprises the solids components of a solvent extract of said root.5. The composition as claimed in claim 1 , comprising solids components of a solvent extract of said root partially purified to increase the active content thereof.6. The A composition as claimed in claim 5 , wherein said partial purification increases the concentration in said solids of flavonoids and/or isoflavones.7. The composition as claimed in claim 1 , wherein said solvent extract is an organic solvent or aqueous extract.8. The composition as claimed in claim 7 , wherein said solvent extract is an ethanol or methanol extract.9Pueraria lobata. A method for the treatment by therapy or prophylaxis of excessive articular cartilage degradation comprising administering to a mammal in need thereof root or extracted mixture of active components thereof formulated for administration to a mammal.10. The method as claimed in claim 9 , comprising administration of a composition which comprises solids components of a solvent extract of said root.11. The method as claimed in claim 10 , wherein said composition comprises solids components of a solvent extract of said root partially purified to increase the active content thereof.12. The method as claimed in claim 11 , wherein ...

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28-03-2013 дата публикации

Method and Composition for Administering Bioactive Compounds Derived From Morinda Citrifolia

Номер: US20130079380A1
Принадлежит: MORINDA HOLDINGS Inc

This invention relates to a method and composition for providing in various health benefits by administering various bioactive compounds derived from the plant Morinda cirtrifolia to individuals. This invention relates to using one or more of the following: Noni Leaf Extract; Noni Leaf Juice; and/or Roast Leaf More particularly this invention relates to administering one or more of the following: Pyro-phorbide a, Pheophorbide a, Purpin 7, and/or Pheophorbide all which may be derived from Noni leaf extract, Noni leaf juice, and/or Roast leaf Moreover, the foregoing formulations result in alleviating pain and inflammation.

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04-04-2013 дата публикации

PHARMACEUTICAL COMPOSITION

Номер: US20130084342A1
Автор: NAKAMORI Toshio
Принадлежит:

A method of treating a respiratory disease in an animal comprising the steps of administering to the animal an effective amount of a pharmaceutical composition comprising 1.5 parts by weight powdered fennel, 2.0 parts by weight powdered rhubarb, 1.0 part by weight powdered glycyrrhiza, 2.0 parts by weight powdered phellodendron bark, 1.0 part by weight powdered zedoary, 1.5 parts by weight powdered picrasma wood, 1.0 part by weight powdered matricaria chamomilla, 1.5 parts by weight powdered geranium herb, 1.0 part by weight powdered ginseng, 1.5 parts by weight powdered citrus unshiu peel, 1.0 part by weight powdered scutellaria root, 1.0 part by weight powdered magnolia bark, 2.0 parts by weight powdered oyster shell, 1.0 part by weight powdered cyperus rhizome, 2.0 parts by weight powdered platycodon root, 2.0 parts by weight powdered melia azedarach, 1.0 part by weight powdered cnidium rhizome, 2.0 parts by weight sodium bicarbonate and 4.0 parts by weight precipitated calcium carbonate in 30 parts by weight of the composition. 1. A method of treating a respiratory disease in an animal comprising the steps of administering to the animal an effective amount of a pharmaceutical composition comprising:1.5 parts by weight powdered fennel;2.0 parts by weight powdered rhubarb;1.0 part by weight powdered glycyrrhiza;2.0 parts by weight powdered phellodendron bark;1.0 part by weight powdered zedoary;1.5 parts by weight powdered picrasma wood;1.0 part by weight powdered matricaria chamomilla;1.5 parts by weight powdered geranium herb;1.0 part by weight powdered ginseng;1.5 parts by weight powdered citrus unshiu peel;1.0 part by weight powdered scutellaria root;1.0 part by weight powdered magnolia bark;2.0 parts by weight powdered oyster shell;1.0 part by weight powdered cyperus rhizome;2.0 parts by weight powdered platycodon root;2.0 parts by weight powdered melia azedarach;1.0 part by weight powdered enidium rhizome;2.0 parts by weight sodium bicarbonate; and4.0 parts ...

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04-04-2013 дата публикации

COMPOSITIONS COMPRISING NON-ACIDIC BOSWELLIA OIL FRACTION AS A BIO-ENHANCER FOR ENHANCING BIOAVAILABILITY OF BIOLOGICAL AGENTS

Номер: US20130084348A1
Принадлежит: LAILA NUTRACEUTICALS

The invention relates to a non-acidic low polar gum resin extract fraction (BLPRE) in combination with biological agents for enhancing the bioavailability of the biological agents. The invention also provides composition(s) comprising a low polar gum resin extract (BLPRE) in combination with a biological agent for increasing the bioavailability of biological agent. 1BoswelliaBoswellia. A bio-enhancing agent derived from a gum resin of a species for enhancing the bioavailability of biological agents , said bio-enhancing agent comprising a low polar gum resin extract (BLPRE) derived from said gum resin.2BoswelliaBoswellia. A composition comprising a bio-enhancing agent derived from a gum resin of a species , said bio-enhancing agent comprising a low polar gum resin extract (BLPRE) derived from said gum resin , said composition further comprising a biological agent;wherein said composition contains said bio-enhancing agent in an amount which is effective for enhancing the bioavailability of said biological agent.3BoswelliaBoswellia serrata, Boswellia carterii, Boswellia papyrifera,. The composition according to claim 2 , wherein said species is selected from the group consisting of and mixtures thereof.4. The composition according to claim 2 , wherein said composition contains said bio-enhancing agent in an amount which is effective for enhancing the bioavailability of said biological agent in a warm blooded animal in need thereof.5. The bio-enhancing composition according to claim 4 , wherein said biological agent is at least one agent selected from the group consisting of a biologically active ingredient claim 4 , an herbal ingredients claim 4 , a dietary supplement claim 4 , a nutrient claim 4 , an antioxidant claim 4 , a vitamin claim 4 , a mineral claim 4 , an amino acid claim 4 , an oil claim 4 , and mixtures thereof.6. The bio-enhancing composition according to claim 4 , wherein the said biological agent comprises one or more ingredients selected from the group ...

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04-04-2013 дата публикации

Methods and compositions for improving the nutritional content of mushrooms and fungi

Номер: US20130084362A1
Принадлежит: PENN STATE RESEARCH FOUNDATION

An improved filamentous fungi is disclosed that has an enhanced nutritional profile by utilizing pulsed ultraviolet irradiation. According to the invention, the vitamin D component of mushrooms and other filamentous fungi may be drastically increased with no deleterious affects on appearance with the use of pulsed UV radiation. Mushrooms so treated had up to 1800% DV in one serving of fresh mushrooms.

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04-04-2013 дата публикации

Process of preparing burdock composite micron essence

Номер: US20130084380A1
Принадлежит: DONG YUAN BIOTECH PHARMACEUTICAL CO Ltd

A process of preparing a burdock composite micron essence at least includes the following. Dissolved and heated phospholipid is added to a vegetable oil extract and then stirred. After stirring, the above mixture is pour into a heated glycerol and then further stirred and a burdock extract aqueous solution is added. The aforementioned mixed solution is stirred at high speed, the emulsion-homogenized solution is subject to high-pressure homogenization, and a filtration membrane is used to filter the homogenized solution obtained to get a purple transparent burdock concentrate. The burdock concentrate is used to prepare the formulation of nano-micro emulsion which is easily absorbed by human body and thus grants improved health benefits.

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04-04-2013 дата публикации

COMPOSITION FOR TREATING BONE DISEASE COMPRISING A GLYCEOLLIN AS AN ACTIVE INGREDIENT

Номер: US20130085178A1

A method for preventing or treating a bone disease, includes administering to a patient having the bone disease a pharmaceutical composition comprising glyceollin as an active ingredient. The active ingredient, glyceollin promotes degradation of the Runx2 protein in osteoblasts and inhibits the mRNA expression of Rankl in osteoblasts to prevent the differentiation of osteoclasts. Furthermore, glyceollin is capable of ameliorating osteoporosis in animal models for osteoporosis. The composition promises drug or food for prevention or treatment of not only osteoporosis but also bone diseases caused by cancer metastatic to the bone. 110-. (canceled)11. A method for preventing or treating a bone disease , comprising administering to a patient having the bone disease a pharmaceutical composition comprising glyceollin as an active ingredient.12. The method according to claim 11 , wherein the bone disease is bone loss or damage due to cancer metastatic to the bone claim 11 , osteoporosis claim 11 , osteomalacia claim 11 , rachitis claim 11 , osteitis fibrosa claim 11 , aplastic bone diseases claim 11 , metabolic bone diseases claim 11 , or a combination thereof.13. The method according to claim 11 , wherein the glyceollin inhibits the differentiation of osteoclasts.14. The method according to claim 11 , wherein the glyceollin promotes degradation of the Runx2 protein in osteoblasts or preosteoblasts.15. The method according to claim 11 , wherein the glyceollin inhibits the mRNA expression of Rankl (receptor-activator of NFκB ligand) in osteoblasts.16. The method according to claim 11 , wherein the glyceollin decreases a bone remodeling rate or a bone turnover rate by inhibiting the differentiation of osteoblasts or osteoclasts.17. The method according to claim 11 , wherein the glyceollin is glyceollin I. This patent application claims benefit under 35 U.S.C. 119(e), 120, 121, or 365(c), and is a National Stage entry from International Application No. PCT/KR2011/003154, ...

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11-04-2013 дата публикации

USE OF PHOTOSYNTHETIC SCAFFOLDS IN TISSUE ENGINEERING

Номер: US20130089521A1
Принадлежит:

The present invention is concerned with a photosynthetic scaffold that delivers oxygen and its uses for tissue engineering and the treatment of ischemia. 117-. (canceled)18. A method of treating damaged or injured cells or tissue in a mammalian organism in need thereof , comprising: delivering a composition comprising photsynthetically active cells to the organism , whereby oxygen is provided to the damaged or injured cells or tissue by the photsynthetically active cells.19. The method of for the use according to , wherein the subject or organism is a mammal20. A composition comprising photosynthetic cells configured for use in a method of treatment of hypoxia in a subject.21. A photosynthetic scaffold configured for growth of tissue , and/or for regeneration , repair and/or maintenance of damaged , injured or missing tissue comprising photosynthetically active cells.22. A photosynthetic scaffold for growth of tissue in vivo comprising photosynthetically active cells supported by a carrier for use in a method of treatment , regeneration , repair and/or maintenance of damaged , injured or missing tissue and/or for treatment or prevention of inflammation in damaged or injured tissue.23. The method of claim 18 , wherein the tissue is dermal claim 18 , cartilage claim 18 , nerve claim 18 , bone and/or blood tissue.24. The scaffold of claim 21 , wherein the scaffold is a matrix made of a polymer network or a decellularized tissue or organ.25. The scaffold of claim 21 , wherein the polymer network is comprised of a biocompatible and/or biodegradable material claim 21 , that can be synthetic claim 21 , natural or a mixture of both claim 21 , particularly a collagenous polymer or fibrinogen.26Chlamydomonas.. The method of claim 18 , wherein the photosynthetically active cells are cells from algae claim 18 , preferably cells from27Chlamydomonas.. The method of claim 18 , wherein at least some of the photosynthetic cells are genetically engineered cells claim 18 , ...

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11-04-2013 дата публикации

METHOD FOR TREATING ATHEROSCLEROSIS

Номер: US20130089601A1
Принадлежит: KAOHSIUNG MEDICAL UNIVERSITY

The invention provides a method for treating atherosclerosis in a subject in need thereof, including administering an effective amount of microRNA-195 to the subject in need thereof. The microRNA-195 may be packaged in a pharmaceutically acceptable carrier. Moreover, the pharmaceutically acceptable carrier may includes a liposome, lipid particle or viral vector. 1. A method for treating atherosclerosis in a subject in need thereof , comprising administering an effective amount of microRNA-195 to the subject in need thereof.2. The method for treating atherosclerosis in a subject in need thereof as claimed in claim 1 , wherein the microRNA-195 is packaged in a pharmaceutically acceptable carrier.3. The method for treating atherosclerosis in a subject in need thereof as claimed in claim 2 , wherein the pharmaceutically acceptable carrier comprises a liposome claim 2 , lipid particle or viral vector.4. The method for treating atherosclerosis in a subject in need thereof as claimed in claim 1 , wherein the subject comprises a mammal.5. The method for treating atherosclerosis in a subject in need thereof as claimed in claim 4 , wherein the mammal comprises a human.6. The method for treating atherosclerosis in a subject in need thereof as claimed in further comprising administering an effective amount of statin to the subject.7. The method for treating atherosclerosis in a subject in need thereof as claimed in claim 6 , wherein the statin comprises simvastatin.8. The method for treating atherosclerosis in a subject in need thereof as claimed in claim 6 , wherein the microRNA-195 and the statin are administered at the same time.9. The method for treating atherosclerosis in a subject in need thereof as claimed in further comprising administering an effective amount of water extract of Panax Notoginseng to the subject.10. The method for treating atherosclerosis in a subject in need thereof as claimed in claim 9 , wherein the microRNA-195 and the water extract of Panax ...

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11-04-2013 дата публикации

COMPOSITION CONTAINING COLORED-BEAN EXTRACTS

Номер: US20130089631A1
Принадлежит: AMOREPACIFIC CORPORATION

The present invention relates to an antithrombotic composition containing a fraction of a colored-bean extract. The antithrombotic composition is highly useful for the treatment of diseases of the circulatory system, including cardiovascular disease, cerebrovascular disease, arteriosclerosis, hypertension and diabetes, which are caused by thrombosis. 1. A method for inhibiting thrombosis , the method comprising administering an effective amount of a resin fraction of a colored-bean extract obtained by extracting with water , a C-Calcohol or a mixture thereof to a subject in such need.2. The method of claim 1 , wherein the concentration of the C-Calcohol is 1-40%(v/v).3. The method of claim 1 , wherein the C-Calcohol includes any one or more selected from the group consisting of methanol claim 1 , ethanol claim 1 , isopropanol claim 1 , n-propyl alcohol claim 1 , n-butanol and isobutanol.4. The method of claim 1 , wherein the colored bean is one or more selected from the group consisting of Seoritae claim 1 , Seomoktae claim 1 , blue bean claim 1 , yellow bean claim 1 , field bean claim 1 , kidney bean claim 1 , pinto bean claim 1 , small red bean claim 1 , small black bean claim 1 , sprouting bean claim 1 , soybean and black soybean.5. The method of claim 1 , wherein the resin fraction is a fraction obtained by fractionation using a synthetic adsorbent column including a polymer of benzene and polystyrene.6. The method claim 1 , of claim 1 , wherein the C-Calcohol is a 5-25% (v/v) ethanol.7. The method of claim 1 , wherein the resin fraction of the colored-bean extract is a fraction by fractionating an ethanol extract of colored beans using a synthetic adsorbent column including a polymer of benzene and polystyrene.8. A method for alleviating or treating vascular disease claim 1 , the method comprising administering an effective amount of a resin fraction of a colored-bean extract by extracting with using water claim 1 , a C1-C5 alcohol or a mixture thereof to a ...

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11-04-2013 дата публикации

Cosmetic Composition for Inhibiting Hair Loss and Enhanced Hair Growth

Номер: US20130089632A1
Принадлежит: Amorepacific Corp

The present disclosure provides a cosmetic composition which includes at least one of Scutellaria baicalensis essence, licorice essence, and mixture of Scutellaria baicalensis extract and licorice extract as active ingredient and, optionally, further includes at least one of zinc pyrithione, panthenol and thuja semen extract. The cosmetic composition of the present disclosure is capable of inhibiting hair loss and enhancing hair growth by inhibiting binding with the androgen receptor and regulating the hair growth factor so as to induce transition from telogen to anagen and prolong anagen.

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18-04-2013 дата публикации

Method And Composition For Improving Skin Barrier Function

Номер: US20130095046A1
Принадлежит:

The invention relates to a method for improving skin lipid barrier function by applying to the skin a composition comprising effective amounts of a protease inhibitor and a cell differentiation enhancer. The composition is useful in promoting skin lipid barrier repair and maintaining the integrity of the lipid barrier. In this regard, the compositions can be used in the treatment and prevention of dry skin, and associated chrono/proto-aging conditions, in the treatment and prevention of irritation on the skin, in the treatment and prevention of UV-related damage to the skin, and in the enhancement of the retention of self-tanning. 1Boswellia. A method for improving skin lipid barrier function comprising applying to the skin a composition comprising from 0.001 to 10% of at least one protease inhibitor which is extract , and from 0.001 to 10% of at least one cell differentiation enhancer which is forskolin.2Boswellia. The method of wherein the extract and the forskolin stimulate the repair of a damaged lipid barrier.3. The method of wherein the composition is applied from 1-2 times per day.4. The method of wherein the composition is applied to skin from 1-2 times per day for 1-3 months.5. The method of wherein the composition further comprises at least one cholesterol.6. The method of wherein the composition contains a mixture of at least one fatty acid claim 1 , at least one ceramide claim 1 , and at least one sterol.7. The method of wherein the composition further comprises a C12-C20 fatty acid.8. The method of containing about 0.05 to 10% of each of cholesterol sulfate claim 1 , fatty acid claim 1 , ceramide claim 1 , and sterol.9. The method of wherein the composition further comprises at least one sunscreen.10. The method of wherein the composition further comprises a self tanning agent.11. The method of wherein the self tanning agent is dihydroxyacetone.12. The method of wherein the composition further comprises cholesterol sulfate.13. The method of wherein the ...

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18-04-2013 дата публикации

COMPOSITION CONTAINING COLORED-BEAN EXTRACT

Номер: US20130095197A1
Принадлежит: AMOREPACIFIC CORPORATION

The present invention relates to an antithrombotic composition comprising a colored-bean extract or a fraction of the extract. The antithrombotic composition is highly useful for the treatment of diseases of the circulatory system, including cardiovascular disease, cerebrovascular disease, arteriosclerosis, hypertension and diabetes, which are caused by thrombosis. 1. A method for inhibiting thrombosis , the method comprising administering an effective amount of a colored-bean extract obtained by extracting with water , a C-Calcohol or a mixture thereof and an organic acid to a subject in such need.2. A method for inhibiting thrombosis , the method comprising administering an effective amount of a fraction of a colored-bean extract obtained by extracting with water , a C-Calcohol or a mixture thereof and an organic acid to a subject in such need.3. The composition of method of claim 1 , wherein the organic acid is any one or more selected from the group consisting of citric acid claim 1 , acetic acid claim 1 , butyric acid claim 1 , palmitic acid claim 1 , oxalic acid claim 1 , tartaric acid claim 1 , carboxylic acid and sulfonic acid.4. The method of claim 1 , wherein the concentration of the C-Calcohol is 1-40% (v/v).5. The method of claim 1 , wherein the C-Calcohol is any one or more selected from the group consisting of methanol claim 1 , ethanol claim 1 , isopropanol claim 1 , n-propyl alcohol claim 1 , n-butanol and isobutanol.6. The method of claim 1 , wherein the C-Calcohol is a 5-25% (v/v) ethanol.7. The method of claim 1 , wherein the extract is a colored-bean extract obtained by extracting with ethanol and an organic acid.8. The method of claim 1 , wherein the colored bean is any one or more selected from the group consisting of Seoritae claim 1 , Seomoktae claim 1 , blue bean claim 1 , yellow bean claim 1 , field bean claim 1 , kidney bean claim 1 , pinto bean claim 1 , small red bean claim 1 , small black bean claim 1 , sprouting bean claim 1 , soybean ...

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18-04-2013 дата публикации

TREATMENT OF CANCER WITH BIO AND CHEMOTHERAPY

Номер: US20130096169A1
Автор: Yu John S.
Принадлежит: CEDARS-SINAI MEDICAL CENTER

This invention relates to compositions and methods utilizing a chemotherapeutic drug and 6-bromoindirubin3′-oxime (BIO) for the treatment of cancer, including glioblastoma multiforme. The present invention demonstrates that BIO works synergistically with chemotherapeutic drugs to increase the cytotoxic effects of these drugs in glioma cells. 1. A method for treating cancer in a subject in need thereof , comprising:providing a glycogen synthase kinase-3 (“GSK-3”) antagonist and/or Wnt canonical pathway agonist and a chemotherapeutic drug; andadministering the GSK-3 antagonist and/or Wnt canonical pathway agonist and the chemotherapeutic drug to the subject to treat the cancer.2. The method of claim 1 , wherein the GSK-3 antagonist and/or Wnt canonical pathway agonist is 6-bromoindirubin-3′-oxime (“BIO”) or methylated BIO (“MeBIO”).3. The method of claim 2 , wherein the GSK-3 antagonist and/or Wnt canonical pathway agonist is BIO.4. The method of claim 2 , wherein the GSK-3 antagonist and/or Wnt canonical pathway agonist is MeBIO.5. The method of claim 1 , wherein the chemotherapeutic drug is selected from the group consisting of temozolomide (“Tmz”) claim 1 , VP-16 claim 1 , paclitaxel claim 1 , carboplatin claim 1 , tumor necrosis factor-related apoptosis-inducing ligand (“TRAIL”) claim 1 , troglitazone (“TGZ”) claim 1 , pioglitazone (“PGZ”) claim 1 , rosiglitazone (“RGZ”) claim 1 , and ciglitazone (“CGZ”) claim 1 , procarbazine claim 1 , vincristine claim 1 , BCNU claim 1 , CCNU claim 1 , thalidomide claim 1 , irinotecan claim 1 , isotretinoin claim 1 , imatinib claim 1 , etoposide claim 1 , cisplatin claim 1 , daunorubicin claim 1 , doxorubicin claim 1 , methotrexate claim 1 , mercaptopurine claim 1 , fluorouracil claim 1 , hydroxyurea claim 1 , vinblastine claim 1 , and combinations thereof.6. The method of claim 5 , wherein the chemotherapeutic drug is Tmz.7. The method of claim 1 , wherein the GSK-3 antagonist and/or Wnt canonical pathway agonist is 6- ...

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25-04-2013 дата публикации

SEMEN CASSIAE SOFT CAPSULE FOR REDUCING FAT AND LOSING WEIGHT AND PREPARATION METHOD THEREOF

Номер: US20130099403A1
Автор: Ma Jianzhong
Принадлежит:

A soft capsule for lowering blood lipids and losing weight and the preparation method thereof. The content of the soft capsule consist of the following components by weight part: 10-60 parts of ethanol soluble extract powder of , 2-10 parts of aqueous soluble extract powder of , 10-30 parts of evening primrose oil, 5-20 parts of sea buckthorn seed oil and 2-10 parts of beeswax. The preparation method includes the following steps: preparing all the components respectively; dissolving the ethanol soluble extract powder of in ethanol, adding 50% of the total weight of beeswax, heating in a water bath at 75 degrees Celsius to obtain a liquid mixture of and beeswax; heating the remainder beeswax with evening primrose oil, adding the liquid mixture of and beeswax while continuously stirring, adding aqueous soluble extract powder of , cooling the mixture by circulation water, adding sea buckthorn seed oil and continuously stirring to obtain the content for soft capsules, encapsulating soft capsules by conventional method to obtain the soft capsule. 1Semen Cassiae. A soft capsule for lowering blood lipids and losing weight , the characteristic of which is: the content of the soft capsule consists of the following components by weight part:{'i': 'Semen Cassiae:', 'Ethanol soluble extract powder of 10-60 parts'}{'i': 'Radix Glycyrrhizae:', 'Aqueous soluble extract powder of 2-10 parts'}Evening primrose oil: 10-30 partsSea buckthorn seed oil: 5-20 partsBeeswax: 2-10 parts2Semen Cassiae. The preparation method of the soft capsule according to claim 1 , the characteristic of which is: the preparation method includes the following steps:{'i': Semen Cassiae', 'Semen Cassiae', 'Semen Cassiae', 'Semen Cassiae., '(1) Preparation of ethanol soluble extract powder of : grind into powder, reflux extract by adding 95% ethanol 10-20 times to the weight of above-mentioned powder, recovery ethanol by vacuum distillation, spray drying the rest of the extract, the product is the ethanol ...

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25-04-2013 дата публикации

SKIN-WHITENING COMPOSITION CONTAINING EXTRACTS FROM TREES INCLUDING PAPER MULBERRY

Номер: US20130101537A1
Принадлежит: AMOREPACIFIC CORPORATION

The present invention relates to a skin-whitening composition comprising a paper mulberry extract, and more particularly to a skin-whitening composition containing an extract of Max., var. var. for. for. or , which can be used safely on the skin without causing side effects and has excellent effects of inhibiting melanin production and pigmentation. 1Acer barbinerveAcer barbinervisglabrescens, Wikstroemia trichotoma, Acer tschonoskiirubripes, Edgeworthia chrysantha, Broussonetia papyriferaOppositifolia, Broussonetia papyriferaLucida, Daphne kamtschticaBroussonetia kazinoki Siebold.. A skin-whitening composition comprising , as an active ingredient , one or more selected from the group consisting of extracts of Max. , var. var. for. for. and2Acer barbinerveAcer barbinervisglabrescens, Wikstroemia trichotoma, Acer tschonoskiirubripes, Edgeworthia chrysantha, Broussonetia papyriferaOppositifolia, Broussonetia papyriferaLucida, Daphne kamtschticaBroussonetia kazinoki Siebold. The skin-whitening composition of claim 1 , wherein the extract of Max. claim 1 , var. var. for. for. and is contained in an amount of 0.0001-90 wt % based on the total weight of the composition.3. The skin-whitening composition of claim 1 , wherein the composition is formulated as a skin-whitening cosmetic product claim 1 , a medical drug or a food. The present invention relates to a skin-whitening composition containing a paper mulberry extract, and more particularly to a skin-whitening composition containing an extract of Max., var. var. for. for. or , which can be used safely on the skin without causing side effects and has excellent effects of inhibiting melanin production and pigmentation.Human skin color is determined by various factors, including the activity of melanocytes which produce the melanin pigment, distribution of blood vessels, skin thickness, the presence or absence pigments such as carotenoids and bilirubin, or the like. Of the factors, the dark pigment melanin which is ...

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25-04-2013 дата публикации

COMPOSITIONS OF BOTANICAL EXTRACTS FOR CANCER THERAPY

Номер: US20130101616A1
Принадлежит:

Methods and compositions for prevention and therapy of cancer are provided. Compositions comprising therapeutically effective amounts of two or more of an extract of , an extract of and an extract of and optionally a therapeutically effective amount of an extract of are provided. Novel synergistic effects of the use of these compounds in combination therapy are disclosed. Embodiments further comprising therapeutically effective amounts of at least one chemotherapeutic agent are also provided. 153-. (canceled)54Ganoderma lucidumSalvia miltiorrhizaScutellaria barbata. An anticancer composition comprising two or more of an organic extract of , an organic extract of and an organic extract of , wherein each extract comprises a therapeutically effective amount.55Ganoderma lucidumScutellaria barbata.. The composition of claim 54 , wherein the composition comprises about 10 to about 50 percent by weight of the composition the extract of and/or about 10 to about 50 percent by weight of the composition the extract of56Ganoderma lucidum, Salvia miltiorrhizaScutellaria barbata. The composition of claim 54 , wherein the organic extract of claim 54 , or is an ethyl acetate extract claim 54 , an alcohol extract claim 54 , a methylene chloride extract claim 54 , or a methanol extract.57. The composition of claim 54 , wherein the composition displays at least one property selected from the group consisting of: anti-inflammatory activity claim 54 , immunoboosting activity claim 54 , inducing lymphocytes to release TNF-alpha claim 54 , and accelerating cell proliferation.58. The composition of claim 54 , wherein the composition selectively inhibits COX-2 over COX-1.59Hippophae rhamnoides.. The composition of further comprising an extract of60. The composition of further comprising a therapeutically effective amount of at least one chemotherapeutic agent.61. The composition of claim 60 , wherein the chemotherapeutic agent perturbs microtubule polymerization.62. The composition of claim ...

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25-04-2013 дата публикации

HERBAL COMPOSITION PHY906 AND ITS USE IN CHEMOTHERAPY

Номер: US20130101688A1
Принадлежит: YALE UNIVERSITY

This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a mammal undergoing such chemotherapy. 117-. (canceled)18. A method of treating cancer in a mammal comprising co-administering a therapeutically effective amount of{'i': Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujuba', 'Paeonia lactiflora, 'i) an herbal preparation consisting essentially of and ; and'}ii) a chemotherapeutic formulation comprising a chemotherapeutic compound.19. The method of claim 18 , wherein the herbal preparation is administered via oral route claim 18 , and the chemotherapeutic formulation is administered via oral or parenteral route.20. The method of claim 19 , wherein the herbal preparation is administered via oral route claim 19 , and the chemotherapeutic formulation is administered via intravenous route.21Scutellaria baicalensis, Glycyrrhiza uralensis, Ziziphus jujubaPaeonia lactiflora. The method of claim 18 , wherein the herbal preparation consists of and claim 18 , and one or more pharmaceutically acceptable carriers.22. The method of claim 18 , wherein the herbal preparation is administered before the administration of the chemotherapeutic formulation.23. The method of claim 18 , wherein the herbal preparation is administered after the administration of the chemotherapeutic formulation.24. The method of claim 18 , wherein the herbal preparation is administered concurrently with the administration of the chemotherapeutic formulation.25. A method of relieving side effects of a chemotherapeutic compound in a mammal comprising co-administering a therapeutically effective amount of{'i': Scutellaria baicalensis, Glycyrrhiza ...

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25-04-2013 дата публикации

COMPOSITION CONTAINING PAPER MULBERRY EXTRACTS

Номер: US20130101689A1
Принадлежит: AMOREPACIFIC CORPORATION

The present invention relates to a composition containing a paper mulberry extract, and more particularly to a composition containing, as an active ingredient, a paper mulberry extract which has effects on enhancement of skin moisturization, inhibition of skin aging, alleviation of inflammation, antibacterial activity, pore size reduction, sebum control, skin complexion improvement, decomposition of subcutaneous fat, stimulation of melanin synthesis, and gray hair prevention. 1. A skin external composition containing a paper mulberry extract as an active ingredient.2. The skin external composition of claim 1 , wherein the extract has an effect on at least one of moisturization claim 1 , anti-aging claim 1 , elasticity improvement claim 1 , wrinkle reduction claim 1 , acne alleviation claim 1 , pore size reduction claim 1 , sebum control claim 1 , trouble alleviation claim 1 , protection of skin from stimuli claim 1 , complexion and skin tone improvement claim 1 , slimming claim 1 , gray hair prevention claim 1 , and leukoplakia prevention.3. The skin external composition of claim 1 , wherein the moisturization effect of the extract is an effect of enhancing skin barrier function or inhibiting keratinocyte differentiation.4Propionibacterium acnes. The skin external composition of claim 1 , wherein the acne alleviation effect of the extract is an effect of inhibiting or inflammation.5. The skin external composition of claim 1 , wherein the slimming effect of the extract is an effect of decomposing triglyceride or removing cellulite.6. The skin external composition of claim 1 , wherein the gray hair or leukoplakia prevention effect of the extract is an effect of stimulating expression of MITF or tyrosinase in melanocytes.7. The skin external composition of claim 1 , wherein the composition is a cosmetic composition.8. The skin external composition of claim 1 , wherein the composition is a pharmaceutical composition.9. The skin external composition of claim 1 , wherein ...

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25-04-2013 дата публикации

SUPPLEMENTS AND METHODS OF SUPPLEMENTATION

Номер: US20130101690A1
Автор: TALBOTT Shawn
Принадлежит: DBC, LLC

The present invention provides supplements, combination supplements, methods of treating inflammation, methods of reducing tension, methods of increasing vigor, and methods of increasing metabolic balance. Further, the invention provides methods for supplementing the diet of an individual, and kits for use in supplementation. The supplements, combination supplements, methods and kits of the present invention may be used to achieve an outcome such as increased vigor, decreased tension, improved metabolic balance, and decreased levels of C-reactive protein. 1Citrus sinensisEurycoma longifoliaCamellia sinensisGarcinia mangostanaGarcinia mangostana. A combination supplement comprising extract , extract , extract , L-theanine , pericarp from the fruit of a L. tree , and juice from the fruit of a L. tree.2. The combination supplement of claim 1 , wherein the combination supplement comprises a plurality of dietary supplements.3. The combination supplement of claim 1 , wherein the combination supplement comprises a first dietary supplement and a second dietary supplement.4Citrus sinensisEurycoma longifoliaCamellia sinensisGarcinia mangostanaGarcinia mangostana. The combination supplement of claim 3 , wherein the first dietary supplement comprises extract claim 3 , extract claim 3 , extract claim 3 , and L-theanine claim 3 , and wherein the second dietary supplement comprises pericarp from the fruit of a L. tree claim 3 , and juice from the fruit of a L. tree.5Citrus sinensis. The combination supplement of claim 4 , wherein the first dietary supplement comprises about 23% to about 30% by weight extract.6Eurycoma longifolia. The combination supplement of claim 4 , wherein the first dietary supplement comprises about 6% to about 15% by weight extract.7Camellia sinensis. The combination supplement of claim 4 , wherein the first dietary supplement comprises about 15% to about 23% by weight extract.8. The combination supplement of claim 4 , wherein the first dietary supplement ...

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25-04-2013 дата публикации

FRUIT AND VEGETABLE-DERIVED COMPOSITIONS FIELD OF THE INVENTION

Номер: US20130101691A1
Принадлежит: Secret of Youth Ltd

This invention provides fruit and vegetable-derived compositions comprising a fruit or vegetable derivative of inter alia, at least one Beta, Capsicum and Malus species, wherein the composition is at a pH in the range of about 3 to about 6.5. The invention further provides for process for the production of the same and uses thereof. 1. A fruit and vegetable-derived composition comprising a fruit or vegetable derivative of at least one Beta , Capsicum and Malus species at a pH in the range of about 3 to about 6.5.2Citrus limonCitrus paradise. The fruit and vegetable-derived composition of claim 1 , further comprising a derivative of at least one of Solanum claim 1 , Cucumis claim 1 , a claim 1 , a claim 1 , and a Prunus.3. The fruit and vegetable-derived composition of claim 2 , further comprising a derivative of a Diospyros.4Citrus maxima.. The fruit and vegetable-derived composition of claim 2 , further comprising a derivative of a5Carica papaya.. The fruit and vegetable-derived composition of claim 2 , further comprising a derivative of a6. The fruit and vegetable-derived composition of wherein said fruit derivative comprises a pulp and a seed of said fruit and optionally a zest claim 1 , a peel or a combination thereof.7. The fruit and vegetable-derived composition of wherein said vegetable derivative comprises a pulp of said vegetable and a peel of said vegetable.8. A method for the treatment or prophylaxis of a dermatologic disease or disorder in a mammal claim 1 , comprising topically applying an effective amount of the fruit and vegetable-derived composition of to the mammal.9. The method according to claim 8 , wherein said dermatologic disease or disorder is psoriasis claim 8 , acne claim 8 , seborrhea claim 8 , eczema claim 8 , skin erosion claim 8 , skin inflammation claim 8 , hair loss claim 8 , diabetic ulcers or lesions claim 8 , wrinkles claim 8 , or skin fissures.10. The method according to claim 8 , wherein said dermatologic disease or disorder is ...

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02-05-2013 дата публикации

METHODS AND COMPOSITIONS FOR ENHANCING STEM CELL MOBILIZATION

Номер: US20130108587A1
Принадлежит: STEMTECH INTERNATIONAL, INC.

A method of using fucoidan to enhance stem cell mobilization in a subject, including hematopoietic stem cells (HSCs) and bone marrow stem cells (BMSCs) is provided. In the method, a blended composition of fruits, mushrooms, microorganisms, maternal fluids, and extracts thereof are used to promote trafficking of stem cells, resulting in migration of the stem cells to specific sties of maintenance an and repair within tissues and/or organs. The method also involves the use of fucoidan obtained from particular algae species to support release and circulation of HSCs, as demonstrated by significantly increase circulation of HSCs in the peripheral blood. Increased circulation of HSCs and/or BMSCs and migration towards sites of maintenance and the natural regeneration mechanisms in the body. Further provided is a dosing regimen for the administration of fucoidan and a method of enhancing release and circulation of stem cells. 1. A method of increasing stem cell mobilization in a subject , comprising:providing a mobilization agent capable of increasing stem cell mobilization; andadministering a quantity of the mobilization agent to the subject in an amount sufficient to increase stem cell mobilization in the subject.2Lycium barbarumspirulinaHericium erinaceusGanoderma LucidumCordyceps Sinensis. The method of claim 1 , wherein the mobilization agent is a composition comprising one or more of the following components selected from the group consisting of: or extracts thereof claim 1 , colostrum or extracts thereof claim 1 , or extracts thereof claim 1 , fucoidan claim 1 , or extracts thereof claim 1 , or extracts thereof claim 1 , and/or or extracts thereof.3. The method of claim 1 , wherein the mobilization agent is fucoidan.4Undaria pinnatifida.. The method of claim 3 , wherein the fucoidan is extracted from5. The method of claim 3 , wherein the quantity of the fucoidan is 250 mg.6. The method of claim 1 , wherein the stem cell is a bone marrow-derived stem cell (BMSC).7. ...

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02-05-2013 дата публикации

METHODS AND USES OF NUR77 AND NUR77 AGONISTS TO MODULATE MACROPHAGES AND MONOCYTES, AND TREAT INFLAMMATION, INFLAMMATORY DISEASE AND CARDIOVASCULAR DISEASE

Номер: US20130108602A1

Methods of decreasing, reducing, inhibiting, suppressing, limiting or controlling an undesirable or aberrant immune response, immune disorder, inflammatory response, or inflammation in a subject; decreasing, reducing, inhibiting, suppressing, limiting or controlling an autoimmune response, disorder or disease in a subject; and decreasing, reducing, inhibiting, suppressing, limiting or controlling an adverse cardiovascular event or cardiovascular disease in a subject, are provided. Methods include, for example, administering a Nur77 polypeptide or subsequence thereof, a Nur77 agonist, or CD14CD16monocytes or CD14CD16(CD115CD11bGR1 (Ly6C−)) monocytes or macrophages to a subject to decrease, reduce, inhibit, suppress, limit or control the underlying condition or an adverse symptom or pathology of the condition. 1. A method of decreasing , reducing , inhibiting , suppressing , limiting or controlling an undesirable or aberrant immune response , immune disorder , inflammatory response , inflammation autoimmune response , autoimmune disease , adverse cardiovascular event or cardiovascular disease in a subject , comprising administering a Nur77 polypeptide or subsequence thereof , a Nur77 agonist , or CD14CD16 monocytes and/or CD14CD16(CD115CD11bGR1 (Ly6C−)) monocytes or macrophages to a subject in an amount to decrease , reduce , inhibit , suppress , limit or control the undesirable or aberrant immune response , immune disorder , inflammatory response , inflammation , autoimmune response , autoimmune disease , adverse cardiovascular event or cardiovascular disease in the subject.23-. (canceled)4. The method of claim 1 , wherein the adverse cardiovascular event or cardiovascular disease comprises coronary artery or heart disease claim 1 , atherosclerosis claim 1 , peripheral artery disease claim 1 , cerebrovascular disease claim 1 , renal artery disease claim 1 , stroke claim 1 , myocardial infarction (heart attack) claim 1 , ischemic heart failure claim 1 , transient ...

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