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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 6507. Отображено 100.
23-02-2012 дата публикации

Process for producing (meth)acrylic acid

Номер: US20120046433A1
Автор: Satoshi Nakagawa
Принадлежит: NIPPON SHOKUBAI CO LTD

A process for producing (meth)acrylic acid, comprising a crystallizing step of supplying a cooling medium from a refrigerator to a crystallizer and returning the cooling medium from the crystallizer to the refrigerator, thereby obtaining a (meth)acrylic acid crystal from a (meth)acrylic acid-containing solution; and a melting step of supplying a heating medium from a refrigerator to the crystallizer and returning the heating medium from the crystallizer to the refrigerator, thereby melting the (meth)acrylic acid crystal; wherein the crystallizing step and the melting step are respectively performed at least once, thereby producing purified (meth)acrylic acid from a crude (meth)acrylic acid solution; temperature of the cooling medium discharged from the refrigerator is maintained constant at temperature T 1 ; temperature of the cooling medium to be returned to the refrigerator is maintained constant at temperature T 2 ; the temperature T 2 is adjusted depending on a production amount of the purified (meth)acrylic acid per unit time.

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Номер записи: 1
19-04-2012 дата публикации

Process for producing adipic acid crystals

Номер: US20120095263A1
Автор: Philippe Carvin, Stephanie Foucher
Принадлежит: Rhodia Operations SAS

A method for producing crystals of adipic acid is described. In particular, a method for recovering adipic acid in the form of crystals with low impurity content, obtained by crystallization steps in particular using reaction media for synthesizing adipic acid is described. A purification method including a step of crushing the crystals for easier removal or the migration of the impurities in the crystals is also described.

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Номер записи: 2
17-05-2012 дата публикации

Additive for the crystallization of proteins, use and process

Номер: US20120123088A1
Автор: Anthony W. Coleman, Antoine Leydier, Frederic Huche, Pierre G. Falson, Rachel Rima Matar Merheb
Принадлежит: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

The present invention relates to the use and to a process involving at least one calix[n]arene derivative substituted by at least one acid functional group on the upper face and at least one aliphatic chain of variable length on the other face, as an additive for crystallization of a polar and/or positively charged molecule. The use and the process of the present invention have the advantage of enabling, facilitating and/or accelerating the crystallization of polar and/or positively charged molecules, especially of membrane proteins that are in solution or soluble, which had previously proved to be very difficult.

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Номер записи: 3
13-09-2012 дата публикации

Systems, materials, and processes for isolating nanoparticles

Номер: US20120227439A1
Автор: Takahisa Kusuura
Принадлежит: EMPIRE TECHNOLOGY DEVELOPMENT LLC

Processes for isolating nanoparticles from an aqueous solution are disclosed. The processes can include, for example, providing an aqueous mixture having a plurality of nanoparticles and at least one thermal hysteresis molecule; adjusting the aqueous mixture to a temperature effective to form ice crystals within the aqueous mixture; and isolating the ice crystals from the aqueous mixture. Also disclosed are compositions and systems for isolating nanoparticles.

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Номер записи: 4
29-11-2012 дата публикации

Extraction process

Номер: US20120297929A1
Автор: Bror Nyman, Eero Ekman, Erkki Paatero, Stig-Erik Hultholm
Принадлежит: OUTOTEC OYJ

A method for the selective recovery of uranium from a sulphate-based acidic aqueous solution of uranium containing iron and other metals by means of solvent extraction, in which the extractant used in the organic extraction solution is bis(2-ethylhexyl) phosphate and a liquid branched trialkyl phosphine oxide is the modifying agent. It is typical of the method that the uranium concentration in the feed solution is less than 50 mg/l and a reducing agent is introduced into the aqueous and/or extraction solution to prevent the permanent oxidation of iron to trivalent. In the method the majority of the extraction solution is circulated in a circuit consisting of the extraction stage and the storage tank and only a small part of the uranium-loaded extraction solution is routed to scrubbing and stripping.

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Номер записи: 5
30-05-2013 дата публикации

PROCESS AND APPARATUS FOR WATER PURIFICATION

Номер: US20130134102A1
Автор: Buchsbaum Norbert Nathan
Принадлежит:

A process for purifying water via freezing is disclosed. The process may include: contacting an aqueous mixture with a flotation medium, wherein the flotation medium has a density greater than or equal to the density of ice or hydrate and less than the density of the aqueous mixture or concentrated brine at its freezing point; reducing the temperature of the aqueous mixture to a temperature equal to or below the freezing point of the aqueous mixture to form ice or hydrate and a concentrate; phase separating the concentrate and the flotation medium; recovering the concentrate; and recovering the ice or hydrate and flotation medium as a slurry. Upon melting, phase separation of the resultant water from the flotation medium may provide a purified water product. 1. A process for purifying water , comprising:contacting an aqueous mixture with a flotation medium, wherein the flotation medium has a density greater than or equal to the density of ice or hydrate and less than the density of the aqueous mixture or concentrated brine at its freezing point;reducing the temperature of the aqueous mixture to a temperature equal to or below the freezing point of the aqueous mixture to form ice or hydrate and a concentrate;phase separating the concentrate and the flotation medium;recovering the concentrate; andrecovering the ice or hydrate and flotation medium as a slurry.2. The process of claim 1 , wherein the flotation medium has a density in the range from about 0.8 to about 1.0 g/cc.3. The process of claim 1 , further comprising melting the ice in the slurry of ice in flotation medium to form an aqueous fraction comprising water.4. The process of claim 1 , further comprising separating the aqueous fraction from the flotation medium.5. The process of claim 1 , further comprising washing the slurry with a wash liquid comprising at least one of fresh water claim 1 , the aqueous fraction claim 1 , and flotation medium claim 1 , which may be the same or different than the flotation ...

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Номер записи: 6
13-06-2013 дата публикации

METHOD OF PRODUCING PHARMACOLOGICALLY PURE CRYSTALS

Номер: US20130149232A1
Автор: Kottwitz Ortwin, Stiefel Thomas
Принадлежит: BIOSYN ARZNEIMITTEL GMBH

The present invention relates to means and methods for producing crystals or crystalline substances. In particular, crystals or crystalline substances which are useful as pharmaceutical ingredients can be manufactured. 1. A process for manufacturing a crystalline substance comprising the steps ofa) delivering an unsaturated solution of the substance to be crystallized into a fluidized bed dryer, under pressure and temperature conditions of applying a vacuum and maintaining a temperature range, in order to dry the solution of a substance to be crystallized to thereby obtain a supersaturated solution, in which crystallization takes place, andb) applying vacuum and maintaining a temperature range in the fluidized bed dryer after completion of the step of delivering the unsaturated solution of the substance to be crystallized, wherein the vacuum and the temperature are regulated in a manner in order to obtain the desired crystalline product as a homogenous product.2. The process of claim 1 , wherein the method does not contain a step of adding a seed crystal.3. The process of claim 1 , wherein in step a) the unsaturated solution is delivered by spraying claim 1 , pumping or sprinkling.4. The process of claim 1 , wherein the unsaturated solution of the substance to be crystallized is delivered into a fluidized bed dryer claim 1 , which is a mechanically created fluidized bed dryer claim 1 , wherein the crystallization takes place under mechanical agitation.5. The process of claim 1 , wherein the crystalline substance is an inorganic or organic salt.6. The process of claim 1 , wherein the temperature and/or vacuum are controlled in step a) and b).7. The process of claim 6 , wherein the temperature and/or vacuum are controlled in step a) and b) in order to avoid sticking of dry substance to the surface of the fluidized bed dryer.8. The process of claim 1 , further comprisingc) adding an amount of free solvent into the fluidized bed dryer, and/ord) regulating pressure and ...

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Номер записи: 7
27-06-2013 дата публикации

Process for making sterile aripiprazole of desired mean particle size

Номер: US20130161848A1
Автор: Donald C. Kientzler, Margaret M. Gleeson, San Kiang, Soojin Kim
Принадлежит: Bristol Myers Squibb Co

A process is provided for making sterile aripiprazole having an average particle size less than 100 microns but preferably greater than 25 microns employing an impinging jet crystallization procedure. The resulting bulk aripiprazole of desired particle size may be used to form a sterile freeze-dried aripiprazole formulation, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks.

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Номер записи: 8
01-08-2013 дата публикации

Process for the Production of a Nanomaterial and Reactor for Implementing it

Номер: US20130196084A1
Автор: Emek Seyrek, Gabriela Popa, Gero Decher, Olivier Felix, Rafael Szamocki, Rita El-Khouri
Принадлежит: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS, Universite De Strasbourg

The present invention relates to a novel process for synthesizing nanomaterials by mixing liquids in a quasi-2D microfluidic reactor. The invention also relates to the reactor for implementing this process.

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Номер записи: 9
05-09-2013 дата публикации

METHOD FOR PRODUCING A COARSE-GRAINED AMMONIUM SULFATE PRODUCT VIA CRYSTALLIZATION AND INSTALLATION FOR OPERATING THE METHOD

Номер: US20130230446A1
Автор: Hofmann Guenter, Leptien Holger, Widua Johannes
Принадлежит: GEA Messo GmbH

Method for the production of a coarse-grained ammonium sulphate product by crystallization and installation for carrying out the method. A method for the continuous production of a coarse-grained ammonium sulphate product from an ammonium sulphate solution in a crystallizer operates in accordance with the DTB principle and has an internal suspension circuit and a clarifying zone, from which a clarified partial flow of solution is constantly drawn off into an external circuit, is heated in a heat exchanger so as to dissolve the solids contained therein and is then guided back as a clear solution into the lower region of the crystallizer. In order to ensure production of a product crystallizate with a grain coarseness which is practically constant over time, a fine crystal suspension flow may be drawn off from the clarifying zone as a further partial flow and guided back into the internal circuit of the crystallization stage without any previous dissolution of the solid proportion contained therein. 1. Method for continuous production of a coarse-grained ammonium sulphate product of a grain size in the range of approximately 2.0-3.0 mm by crystallization of an ammonium sulphate solution in a crystallization stage which is operated in accordance with a draft tube baffled (DTB) principle , said method comprising:constantly circulating a suspension of mother solution and ammonium sulphate crystals in an internal circuit while evaporating water from the solution;drawing off a clarified partial flow of solution from a clarifying zone in an upper region of the crystallization stage into an external circuit;heating the solution so as to dissolve the solids contained therein and then guiding the solution back as a clear solution into a lower region of the crystallization stage, and continuously drawing off vapours from a head of the crystallization stage;supplying new ammonium sulphate solution from outside and drawing off a suspension flow containing the coarse-grained ...

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Номер записи: 10
26-09-2013 дата публикации

Crucible for Solidifying a Silicon Ingot

Номер: US20130247334A1
Автор: FLAHAUT EMMANUEL, HUGUET Charles, Lignier Hélène
Принадлежит: Commissariat A L'Energie Atomique Et Aux Energies Alternatives

The present invention relates to a crucible that can be used for solidifying a silicon ingot from molten silicon, characterized in that same is at least partially coated on the inner surface thereof with at least one layer consisting of a material produced by thermal decomposition of polysilizane(s), said layer having a shear strength greater than 1 Pa and no higher than 500 MPa, and being in the form of a stack of adjoining layers of non-contiguous tiles. The invention also relates to a method for preparing such crucibles. 122.-. (canceled)23. A crucible useful for solidifying a silicon ingot from molten silicon coated at least partially on an inner surface with at least one layer formed from a material obtained by thermal decomposition of polysilazane(s) , the layer having a shear strength greater than 1 Pa and less than or equal to 500 MPa and comprised of a stack of contiguous strata of non-touching tiles.24. The crucible of claim 23 , wherein each of the strata of tiles forming the stack is between 0.2 and 50 μm thick.25. The crucible of claim 23 , wherein the stack is between 10 and 500 μm thick.26. The crucible of claim 23 , wherein the stack comprises from 2 to 100 strata of tiles and the strata are superposed and contiguous.27. The crucible of claim 23 , wherein the layer has a shear strength less than or equal to 300 MPa.28. The crucible of claim 23 , wherein the layer comprises silicon carbide SiC claim 23 , silicon nitride SiNand/or silicon oxycarbonitride.29. The crucible of claim 23 , wherein the tiles are made of silicon carbide SiC claim 23 , silicon nitride SiN claim 23 , a mixture of SiC and SiN claim 23 , or silicon oxycarbonitride SiCNO.30. The crucible of claim 23 , wherein the tiles forming all of the strata constituting the layer are made of the same material.31. The crucible of claim 23 , wherein the tiles forming all of the strata constituting the layer are made of two different materials.32. The crucible of claim 23 , wherein the tiles are ...

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Номер записи: 11
02-01-2014 дата публикации

Process and equipment for sugar crystallization by controlled cooling

Номер: US20140000586A1
Автор: Paulo Eduardo Mantelatto
Принадлежит: Dedini SA Industrias de Base

A process is proposed for crystallizing, by progressively cooling, in multiple stages arranged in series in a crystallization vessel ( 10 ), a descending continuous flow of a saturated sucrose solution at a temperature from about 78° to about 120° C., each stage maintaining the sucrose solution being crystallized at a predetermined temperature, until reaching a temperature from about 25 to 40° C., obtaining substantially pure sucrose crystals. A suspension containing sugar seeds is introduced in the crystallizing equipment, in the first stage, jointly with the saturated sucrose solution of 1.05-1.15. In another embodiment of the invention, the saturated solution is fed and its temperature is controlled, already in the first stage of the vessel ( 10 ), to obtain a supersaturation between 1.05 and 1.15, inducing the formation of small crystals used as crystallization seeds.

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Номер записи: 12
13-02-2014 дата публикации

APPARATUS AND METHOD FOR SEPARATING SOLID PARTICLES FROM A SLURRY

Номер: US20140042108A1
Автор: COLLARD Jean-Marie, Nienoord Michiel, Sell Michael, Van der Meer Johannes, Verdoes Dirk
Принадлежит: NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUUREWET- ENSCHAPPELIJK CONDERZOEK

The invention is directed to an improvement in operation of wash columns, and more in particular to an apparatus for separating solid particles from a slurry and to a process for separating solid particles from a mother liquor slurry. The apparatus of the invention comprises a wash column (), which comprises a melting circuit (), wherein means () are present to introduce a compound or composition to said wash column between a wash front () formed in said wash column in operation and a product outlet and/or in the melting circuit. The process of the invention comprises separating the liquid from the solid particles by filtration with the aid of at least one filtering element (), while a packed bed of solid particles coming from the mother liquid slurry forms near said filtering element (), and wherein a wash front () forms which is obtained by bringing a washing liquid in counter current to the solid particles in the bed, the bed being subjected to a movement in the direction of said wash front (), while a product stream comprising the material of said solid particles is obtained by continuously discharging a portion of said washing liquid, wherein a portion of said bed is continuously disintegrated, characterized in that a compound or composition is introduced into said wash column () between the wash front () and a product outlet and/or in a melting circuit (), and wherein the introduction of the said compound or composition decreases the equilibrium temperature of the contents of the melting circuit (), further characterized by the feature that the introduced compound or composition is completely miscible with the product suspension and/or molten product being present in the said melting circuit (). 1. Apparatus for separating solid particles from a mother liquor slurry , comprising a wash column , which comprises a melting circuit , wherein means are present to introduce a compound or composition to said wash column between a wash front formed in said wash column ...

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Номер записи: 13
20-03-2014 дата публикации

Thermoelectric device with make-before-break high frequency converter

Номер: US20140076826A1
Автор: Gerald Philip Hirsch, Jon Murray Schroeder
Принадлежит: Individual

An improved circular multi-element semiconductor thermoelectric hybrid utilizes a make-before-break high frequency switching output component to provide nominal alternating current voltage outputs. Overall efficiency of heat conversion is improved by coupling a chiller to the thermoelectric generator where exhaust heat produces chilled liquid or air that is conveyed to the cold side of the thermoelectric device. The thermoelectric generator is used in a variety of transportation vehicles including manufactured vehicles, retrofitted vehicles and vehicle power combinations.

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Номер записи: 14
02-01-2020 дата публикации

APPARATUS FOR PURIFYING CRYSTALS USING SOLVENT VAPORS

Номер: US20200001200A1
Автор: Bethers Pratt, Goodman, III David
Принадлежит:

A Reflux Rinsing apparatus for purifying crystals using solvent vapor through dynamic equilibrium recrystallization. A pressure vessel contains a liquefied gas solvent, impure crystalline starting material initially, and a purified crystalline mass at the conclusion of the purifying process. A mechanism is provided for providing pressure to contents of the pressure vessel and for heating the lower portion thereof. A timer is also connected to the mechanism, the timer being set to heat the pressure vessel to drive vapors and reflux rinsing to remove impurities at the surface of an impure crystalline mass, to reclaim the solvent, leaving purified crystals and impurities in the pressure vessel, and to open the pressure vessel to remove the purified crystals from the vessel walls and bottom surface and to remove the impurities from the vessel. The angle of a crystal bed in the apparatus can be adjusted. 1. A Reflux Rinsing apparatus for purifying crystals using solvent vapor through dynamic equilibrium recrystallization , comprising:a) a pressure vessel having walls, a lower portion with a bottom surface, and an upper portion, the pressure vessel for containing a liquefied gas solvent, impure crystalline starting material initially, and a purified crystalline mass at the conclusion of the purifying process;b) means for providing pressure to contents of the pressure vessel;c) means for heating the lower portion of the pressure vessel; and i) gently heat the lower portion of the pressure vessel to drive vapors and reflux rinsing to remove impurities at the surface of a purified crystalline mass;', 'ii) cycling step (i) with control over temperature and pressure as necessary to maximize crystal yield and purity;', 'iii) reclaiming the solvent, leaving the crystals and impurities in the pressure vessel; and', 'iv) opening the pressure vessel to remove the purified crystalline mass from the walls and bottom surface of the vessel and the impurities from the lower portion ...

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Номер записи: 15
02-01-2020 дата публикации

METHOD FOR PURIFYING CRYSTALS USING SOLVENT VAPORS

Номер: US20200002306A1
Автор: Bethers Pratt, Goodman David
Принадлежит:

A Reflux Rinsing method for purifying crystals using solvent vapor through dynamic equilibrium recrystallization. Feed material having tetrahydrocannabinol (THC) is inserted into a reaction vessel having walls, and upper portion, and a lower portion with a bottom surface. The feed material is exposed to a hydrocarbon liquid in the reaction vessel in a quantity sufficient to keep liquid present in equilibrium with gas in the reaction vessel through the recrystallization process, forming a raw extract having THC. The walls and bottom surface of the reaction vessel are coated with raw extract. The reaction vessel is heated and then the heating is discontinued. Vapor/thin-film DER is promoted in the reaction vessel for a predetermined length of time with no solvent reflux, resulting in formation of purified crystals of THC acid under pressure. The hydrocarbon solvent is reclaimed from the reaction vessel, leaving the purified crystals and impurities. When the reaction vessel is opened, the purified crystals and impurities are removed. 1. A method for purifying crystals using solvent vapor through dynamic equilibrium recrystallization (DER) , the steps comprising:a) inserting feed material having tetrahydrocannabinol (THC) into a reaction vessel having walls, an upper portion, and a lower portion with a bottom surface;b) exposing the feed material to a hydrocarbon liquid in the reaction vessel in a quantity sufficient to keep liquid present in equilibrium with gas in the reaction vessel through the recrystallization process, forming a raw extract having THC;c) coating the walls and the bottom surface of the reaction vessel with raw extract;d) heating the reaction vessel;e) discontinuing the heating step (d):f) forming purified crystals of THC acid under pressure;g) reclaiming the hydrocarbon solvent from the reaction vessel, leaving therein the purified crystals of THC acid and impurities; andh) opening the reaction vessel and removing the purified crystals of THC acid ...

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Номер записи: 16
12-01-2017 дата публикации

FREEZING DESALINATION MODULE

Номер: US20170008778A1
Автор: AL-BEIRUTTY MOHAMMED HUSSAIN, ALY SAMIR ELSAYED, BOUGUECHA SALAH AL-TAHAR
Принадлежит:

The freezing desalination module includes a pair of desalination units coupled to a pair of refrigeration units. A pre-cooling tank and a freezing tank is disposed in each desalination unit. A feed line, a desalinated line, and a brine line are coupled to the freezing desalination module to respectively enable feeding of raw feed water (RFW) through the module, collect desalinated water, and remove brine/ice wash for further processing. The RFW in the pre-cooling tank is pre-cooled by a pair of heat exchangers, through which flows cooler desalinated water and the brine/ice wash, respectively. The freezing tank of both desalination units are in communication with the refrigeration units so that as one freezing tank performs freezing, the other is melting. A perforated plate divides each freezing tank into an upper chamber where freezing desalination process occurs and a lower chamber where brine/ice wash collect and feed through the pre-cooling tank. 1. A freezing desalination module , comprising:a pair of refrigeration units;a pair of desalination units coupled to the refrigeration units, each of the desalination units producing desalinated water and brine/ice wash from selective freezing and melting of raw feed water by the refrigeration units, each of the desalination units having a first tank for holding and pre-cooling raw feed water and a second tank for freezing and melting the raw feed water;a feed line coupled to each of the desalination units to feed raw feed water to each of the first tanks;a desalination line coupled to each of the first tanks to collect desalinated water;a brine line coupled to each of the first tanks to discharge the brine/ice wash;a plurality of pumps coupled to the feed lines, the first tanks, and the second tanks to transfer raw feed water, desalinated water, and brine/ice-wash therebetween; anda power source coupled to the desalination units to provide power for operation of the refrigeration units and the pumps;wherein each of the ...

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Номер записи: 17
08-01-2015 дата публикации

Extraction of uranium from wet-process phosphoric acid

Номер: US20150010446A1
Автор: Bryn Llywelyn Jones, Colin Wayrauch, James Andrew Davidson, Jessica Mary Page, Karin Helene Soldenhoff, Marcus Worsley Richardson, Mark S. Chalmers, Paul Robert Kucera, Peter Douglas Macintosh
Принадлежит: URTEK LLC

A process for extracting uranium compounds from wet-process phosphoric acid (WPA) includes lowering iron content of WPA to produce a lowered iron WPA, reducing valency of any remaining iron in the lowered iron WPA to produce a reduced iron valency WPA. Uranium compounds are extracted from the reduced iron valency WPA via a solvent extraction process.

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Номер записи: 18
03-02-2022 дата публикации

Synthesis of ammonium dinitramide (adn)

Номер: US20220033262A1
Автор: Jonas Johansson, Stefan EK
Принадлежит: TotalFoersvarets Forskningsinstitut FOI

The invention concerns a method for making ammonium dinitramide from guanylurea dinitramide in one single process step. Guanylurea dinitramide is reacted with an ammonium sulfate in a reaction solution comprising water and acetone and an ion exchange gives ammonium dinitramide. By using acetone the yield is increased compared to known processes as formed guanylurea sulfate is poorly soluable in a water-acetone solution and precipitates, while guanylurea dinitramide has higher solubility in the solution than in only water. The guanylurea sulfate precipitate formed in the reaction solution that contains acetone is less sticky than if formed in water or in a water-alcohol solution and therefore easier to filter off. The use of acetone also allows lower process temperatures to be used than in previously known methods for producing guanylurea dinitramide. Conclusively, the method gives a higher yield, demands considerable smaller amounts of solvent and allows lower process temperatures to be used than in any formerly known process.

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Номер записи: 19
18-01-2018 дата публикации

Eutectic freeze crystallization spray chamber

Номер: US20180016160A1
Автор: Ben Enis, Paul Lieberman
Принадлежит: Enisenergen LLC

A wastewater purifier has a chamber having an upper ingress end and a lower drain end, one or more wastewater nozzles connected to a wastewater source positioned near the ingress end, to produce wastewater droplets, a chilled air ingress positioned near the ingress end, connected to a chilled air source, positioned to permit the chilled air to mix with the wastewater droplets, a perforated accumulator near the drain end adapted to collect frozen droplets, a drain below the accumulator, and an egress for the chilled air near the drain end. A wastewater purifier has an elongated flow chamber having an upper portion and lower portion, one or more wastewater nozzles positioned near the upper portion, one or more egress vents positioned near the upper portion, a perforated accumulator at the bottom of the chamber, and a chilled air ingress connected between the upper and lower portions.

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Номер записи: 20
22-01-2015 дата публикации

CRYSTALLIZATION REACTION APPARATUS FOR RECOVERING RESOURCES

Номер: US20150023847A1
Автор: Kang Seok-Woong
Принадлежит:

Provided is a crystallization reaction apparatus for recovering resources, which includes at least one agitating impeller provided inside, a seed injection port provided to improve a crystallization effect, and plug-flow formed using at least one isolation layer in order to remove nutrient salts, such as phosphorus (P) and nitrogen (N), exiting in an effluent to cause eutrophication, are removed, the effluent being produced from a dehydration process for sludge discharged through a digestion tank in an sludge waste treatment process for the nutrient salts, such as phosphorus (P) and nitrogen (N), existing in a wastewater treatment water to cause eutrophication, wastewater sludge, food waste and excreta of livestock. 1. A crystallization reaction apparatus comprising:a driving unit coupled to a rotational shaft to rotate the agitating impeller; the agitating impeller installed at the rotational shaft coupled to the driving unit to agitate a treatment liquid or an effluent;a crystallization reactant injected to crystallize phosphorus and nitrogen contained in the treatment liquid or the effluent; anda treatment liquid or effluent injection port and a treatment liquid discharge port for discharge after a reaction has been performed.2. The crystallization reaction apparatus of claim 1 , further comprising a sedimentation guide isolation member that moves crystals claim 1 , which are agitated by the agitating impeller and generated through a crystallization reaction claim 1 , down through a hole formed in a center of the sedimentation guide isolation member after the crystals are sunken claim 1 , without directly discharging the crystals through the treatment liquid discharge port placed at an upper portion of a reactor.3. The crystallization reaction apparatus of claim 2 , further comprising a crystalline germ injection port which injects a crystalline germ to accelerate the reaction.4. The crystallization reaction apparatus of claim 3 , wherein the crystalline germ ...

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Номер записи: 21
25-01-2018 дата публикации

SALT PRODUCTION AUTOMATION SYSTEM UTILIZING THREE-DIMENSIONALLY STRUCTURED EVAPORATION FIELDS

Номер: US20180021694A1
Автор: PARK Yong Hee
Принадлежит:

Provided a salt production automation system utilizing three-dimensionally structured evaporation fields. The salt production automation system utilizing three-dimensionally structured evaporation fields includes: evaporation fields which have collection pools (SWT) and are installed in at least two separate places; a plurality of evaporation members which are three-dimensionally arranged in the evaporation fields to make seawater flow downwards; and a seawater supply unit which supplies seawater to the evaporation members so that seawater can flow downwards from the evaporation members, wherein among the evaporation fields, the number of evaporation members gradually decreases from the first stage evaporation field to the final stage evaporation field. 1. A salt production automation system utilizing three-dimensionally structured evaporation fields , the system comprising:{'b': '20', 'an evaporation field () having a retention pond;'}{'b': 30', '20, 'a plurality of evaporation members () three-dimensionally disposed in the evaporation field () to allow seawater to flow down thereon;'}{'b': 30', '30, 'a seawater supply unit supplying seawater to the evaporation members () so that the seawater flows down on the evaporation members (); and'}{'b': 30', '40', '20', '40, 'a seawater circulation unit supplying seawater to the evaporation members () from a seawater tank () by returning the seawater dropping to the retention pond at the evaporation field () to the seawater tank () of the seawater supply unit (when the seawater flowing down in the retention pond has salt concentration equal to or less than a predetermined level).'}220303030. The system of claim 1 , wherein the evaporation field () receives water claim 1 , which is supplied to the evaporation members () from the seawater supply unit and flows down on the evaporation members () claim 1 , in the retention pond claim 1 , and the retention pond has a collection pool (SWT) for collecting the seawater flowing down ...

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Номер записи: 22
26-01-2017 дата публикации

SYSTEM AND METHODS FOR REMOVING IMPURITIES FROM PHOSPHOGYPSUM AND MANUFACTURING GYPSUM BINDERS AND PRODUCTS

Номер: US20170022070A1
Автор: DASHEVSKY Boris, KOSSON David Samuel, KOVLER Konstantin, RECHES Yonathan
Принадлежит:

Methods and systems that remove impurities from phosphogypsum (PG), including from radium and heavy metal salts, and produce gypsum binders and products. In one embodiment, PG is reacted with a chloride solution in an acidic environment under mechanical manipulation and/or heat followed by galvanic and/or zeolite absorption removal of impurities. 186.-. (canceled)87. A method of removing impurities from phosphogypsum (PG) , the method comprising:at a temperature between about 85 to about 150° C., reacting PG with a chloride solution to form a PG sludge, wherein the concentration of the chloride solution is between about 10% to about 50% and wherein metal ions present in the PG crystal matrix move into solution by action of the chloride ions present in the chloride solution;dehydrating a resulting sludge for about 5 minutes to about 5 hours at a temperature between about 85 to about 150° C.;at a cathode, galvanically removing contaminants having a lower electrode potential than hydrogen from the resulting sludge while maintaining temperature of the reaction slurry;filtering the resulting PG sludge to separate a solid fraction containing alpha-hemihydrate gypsum crystals from a liquid waste fraction; andneutralizing the alpha-hemihydrate calcium sulfate crystal solution.88. The method of claim 87 , further comprising galvanically removing contaminants from the PG sludge.89. The method of claim 87 , wherein the chloride solution is CaCl.90. The method of claim 87 , wherein during the reaction of PG with the chloride solution claim 87 , metal ions present in the PG crystal matrix move into solution by action of the chloride ions present in the chloride solution.91. The method of claim 87 , wherein reacting the PG with the chloride solution takes place under mechanical manipulation.92. The method of claim 87 , wherein reacting the PG with the chloride solution takes place at a pH of about 6 to about 1.93. The method of claim 87 , wherein reacting the PG with the chloride ...

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Номер записи: 23
29-01-2015 дата публикации

Methods, Devices, and Systems for the Separation and Concentration of Isotopologues

Номер: US20150027165A1
Автор: Charlie Booth, Keith Moser, Randall N. Avery
Принадлежит: Exelon Generation Co LLC, Industrial Idea Partners

The present invention is a novel method for removing tritium oxide contamination from a solution with water. The method captures the tritium oxide in a much smaller volume suitable for economical disposal. In so doing the original water is decontaminated of the tritium oxide and may be discharged.

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Номер записи: 24
24-04-2014 дата публикации

Fuel preparation for use in the production of medical isotopes

Номер: US20140112858A1
Автор: Scott B. Aase, Timothy A. POLICKE, William R. Stagg
Принадлежит: Babcock and Wilcox Technical Services Group Inc

The present invention relates generally to the field of medical isotope production by fission of uranium-235 and the fuel utilized therein (e.g., the production of suitable Low Enriched Uranium (LEU is uranium having 20 weight percent or less uranium-235) fuel for medical isotope production) and, in particular to a method for producing LEU fuel and a LEU fuel product that is suitable for use in the production of medical isotopes. In one embodiment, the LEU fuel of the present invention is designed to be utilized in an Aqueous Homogeneous Reactor (AHR) for the production of various medical isotopes including, but not limited to, molybdenum-99, cesium-137, iodine-131, strontium-89, xenon-133 and yttrium-90.

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Номер записи: 25
01-02-2018 дата публикации

Enhanced process for selective salt recovery from wastewater, waste salts, and brines

Номер: US20180029904A1
Автор: Sebastien BESSENET, Timothy J. Rittof
Принадлежит: Veolia Water Technologies Inc

A process for treating wastewater or waste brines that include sodium and chloride ions. The waste brine is concentrated and thereafter directed to a Mirabilite crystallizer that produces hydrated sulfate salt crystals and a first solution. The hydrated crystals are melted to form an aqueous sulfate solution that is directed to a sodium sulfate crystallizer which produces sodium sulfate salt crystals. The first solution produced by the Mirabilite crystallizer is directed to a nanofiltration device which produces a permeate stream and a reject stream containing sulfate removed by the nanofiltration device. The permeate stream is directed to a sodium chloride crystallizer that produces sodium chloride salt crystals. The reject stream is recycled to the Mirabilite crystallizer.

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Номер записи: 26
01-05-2014 дата публикации

Reactor designs for use in ammonothermal growth of group-iii nitride crystals

Номер: US20140116326A1
Автор: Derrick Shane Kamber, James S. Speck, Shuji Nakamura, Siddha Pimputkar
Принадлежит: UNIVERSITY OF CALIFORNIA

Reactor designs for use in ammonothermal growth of group-III nitride crystals. Internal heating is used to enhance and/or engineer fluid motion, gas mixing, and the ability to create solubility gradients within a vessel used for the ammonothermal growth of group-III nitride crystals. Novel baffle designs are used for control and improvement of continuous fluid motion within a vessel used for the ammonothermal growth of group-III nitride crystals.

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Номер записи: 27
30-01-2020 дата публикации

METHOD FOR PREPARING (R)-N-[4-(1-AMINO-ETHYL)-2,6-DIFLUORO-PHENYL]-METHANESULFONAMIDE

Номер: US20200031766A1
Автор: CHOI Chang Soon, JAYAPRAKASH Sarva, LEE Jihae, LEE Ki-Wha, PARK Miyoung, PARK Young-ho, PATEL Krushnakant, RAMAMOHAN M., REGATI Sridhar, SRINIVAS Mamidi, WOO Byoung young
Принадлежит: AMOREPACIFIC CORPORATION

Disclosed in the present specification is a method capable of preparing N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]-methanesulfonamide (INT028-2) with high optical purity, through the selection of Ellman-chiral auxiliaries and the re-crystallization and separation of optical isomers. According to the above method, high-purity N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]-methanesulfonamide with excellent quality can be produced at room temperature by improving cryogenic process conditions necessary for realizing high optical purity, and thus the trimming due to the process failure rate can be remarkably reduced. 1. A method for preparing (R)—N-[4-(1-aminoethyl)-2 ,6-difluoro-phenyl]-methanesulfonamide , the method comprising:a recrystallization step including putting and stirring a stereoisomeric mixture in which optical isomers of N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]-methanesulfonamide are mixed in a specific solvent and obtaining a solid which is precipitated in a solution phase and contains N-[4-[(1R)-1-[[(R)-(1,1-dimethylethyl)sulfinyl]amino]ethyl]-2,6-difluorophenyl]-methanesulfonamide, whereinthe solvent in the recrystallization step includes one or more kinds selected from the group consisting of isopropyl alcohol (IPA), methanol (MeOH), ethyl acetate (EtOAc), toluene, and isopropyl acetate.2. The method for preparing (R)—N-[4-(1-aminoethyl)-2 claim 1 ,6-difluoro-phenyl]-methanesulfonamide according to claim 1 , wherein the solvent in the recrystallization step is selected from the group consisting of isopropyl alcohol (IPA) claim 1 , methanol:ethyl acetate (MeOH:EtOAc) (1:8) claim 1 , methanol:ethyl acetate (1:6) claim 1 , ethyl acetate (EtOAc) claim 1 , ethyl acetate:toluene (1:2) claim 1 , ethyl acetate:toluene (1:1) claim 1 , and isopropyl acetate.3. The method for preparing (R)—N-[4-(1-aminoethyl)-2 claim 1 ,6-difluoro-phenyl]- ...

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Номер записи: 28
04-02-2021 дата публикации

Formation of High Quality Alane

Номер: US20210032103A1
Автор: MCWHORTER CHRISTOPHER S., WARD PATRICK A., ZIDAN RAGAIY
Принадлежит:

Methods for forming alane are described. The method includes addition of toluene at a temperature above the crystallization temperature of alane to a lower temperature solution that includes alane adduct, ether, and toluene. Upon the addition, a crystallization mixture is formed that is at or near the crystallization temperature of alane. The alane of the mixture crystallizes over a period of time to form a high purity alane polymorph. 1. A method for forming alane comprising:combining an alane adduct, an ether, and a first amount of toluene to form a liquid mixture, the liquid mixture including the ether in an amount of from about 1 vol. % to about 50 vol. %;adding a second amount of toluene to the liquid mixture to form a crystallization mixture, wherein at the addition, the liquid mixture is at a temperature of from about 15° C. to about 45° C. and the second amount of toluene is at a temperature that is greater than the crystallization temperature of the alane, wherein upon the addition, the crystallization mixture thus formed is at a temperature of from about 70° C. to about 80° C.; andmaintaining the crystallization mixture at a temperature of from about 70° C. to about 80° C. for a period of from about 2 hours to about 5 hours, the alane of the alane adduct polymerizing during the period.2. The method of claim 1 , wherein the alane adduct is an alane etherate adduct.3. The method of claim 1 , wherein the liquid mixture includes the ether in an amount of from about 1 vol. % to about 15 vol. %.4. The method of claim 1 , wherein the liquid mixture includes the ether in an amount of from about 25 vol. % to about 50 vol. %.5. The method of claim 1 , wherein the ether comprises diethyl ether.6. The method of claim 1 , wherein the second amount of toluene is at a temperature of from about 65° C. to about 110° C.7. The method of claim 1 , wherein the second amount of toluene is at a temperature of from about 65° C. to about 100° C.8. The method of claim 1 , wherein ...

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Номер записи: 29
05-02-2015 дата публикации

Process And System For Purification Of Aromatic Dicarboxylic Acid

Номер: US20150038737A1
Автор: Gray Julian Stuart, Winter Michael William
Принадлежит: DAVY PROCESS TECHNOLOGY LIMITED

In a process/system for the purification of aromatic dicarboxylic acid (ACA), crude ACA solids are slurried with water recycled from at least a filtration step in a feed preparation zone. Flash steam in vapour phase is supplied to the zone from at least one of a crystallisation step, a filtration step, and a drier step. The slurried ACA solids are preheated to form a solution that is then hydrogenated. The ACA is allowed to crystallise and then crystals of pure ACA are filtered out and water is recovered in a single stage filtration process. Recovered water is supplied to the feed preparation zone and the crystals are dried and recovered. The flash steam recovered from the crystallisation step, filtration step and/or drier step is recovered as a vapour phase stream having a pressure from about atmospheric to 5 barg and supplied to the feed preparation zone without phase change. 1. A process for the purification of aromatic dicarboxylic acid comprising the steps of:(a) slurrying crude aromatic dicarboxylic acid solids with water recycled from at least a filtration step in a feed preparation zone;(b) supplying flash steam in vapour phase to the feed preparation zone from at least one of a crystallisation step, a filtration step, and a drier step;(c) preheating the slurried aromatic dicarboxylic acid solids to form a solution;(d) subjecting the heated solution to hydrogenation;(e) allowing pure aromatic dicarboxylic acid to crystallise;(f) filtering out the crystals of pure aromatic dicarboxylic acid and recovering water in a single stage filtration process;(g) supplying at least part of the recovered water to the feed preparation zone; and(h) drying the filtered crystals and recovering same, wherein the flash steam recovered from at least one of a crystallisation step, a filtration step or a drier step is recovered as a vapour phase stream having a pressure of from about atmospheric to 5 barg and is supplied to the feed preparation zone without phase change.2. A ...

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Номер записи: 30
05-02-2015 дата публикации

METHOD FOR PROCESSING RADIOACTIVELY-CONTAMINATED WATER

Номер: US20150038760A1
Автор: WAKAYAMA Seiko, WAKAYAMA Toshitsugi
Принадлежит: Showa Freezing Plant Co., Ltd.

The present invention provides an efficient and low cost method for processing radioactively-contaminated water. The method for processing radioactively-contaminated water comprising a freeze concentration step of generating ice having lowered concentration of radioactive substance from radioactive substance containing contaminated water and concentrating the radioactive substances in the residual contaminated water by the interface progressive freeze concentration process. Preferably, the method further comprises a nitrogen substitution step of reducing dissolved oxygen in the contaminated water and adding nitrogen gas to the contaminated water, as a previous step of the freeze concentration step. Preferably, the radioactive substance is radioactive cesium. 1. A method for processing radioactively-contaminated water comprising:adding nitrogen gas to contaminated water containing an initial concentration of a radioactive substance, to chemically stabilize the contaminated water by reducing dissolved oxygen therein; andafter adding nitrogen gas, freezing at least a portion of the contaminated water such that the frozen portion has a lower concentration of the radioactive substance than the initial concentration, and a residual unfrozen portion of the contaminated water has a higher concentration of the radioactive substance than the initial concentration.2. (canceled)3. (canceled)4. The method for processing radioactively-contaminated water according to claim 1 , wherein the radioactive substance is radioactive cesium. This application claims priority to Japanese Patent Application No. 2013-157310, filed on Jul. 30, 2013, which is hereby incorporated by reference.The present invention relates to a processing method for decontaminating radioactive substances from radioactively-contaminated water.A large amount of contaminated water containing radioactive cesium caused by the accident of the nuclear power plant is generating, therefore, developing an efficient process ...

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Номер записи: 31
08-02-2018 дата публикации

Process Scheme To Improve Divalent Metal Salts Removal From Mono Ethylene Glycol (MEG)

Номер: US20180037527A1
Автор: Luis Eduardo Caires Fernandez
Принадлежит: Cameron International Corp

A MEG reclamation process includes the step of increasing above 2,000 ppm the divalent metal salts concentration of a rich (wet) MEG feed stream flowing into a precipitator. The increasing step includes routing a salts-saturated MEG slipstream from the flash separator it to the precipitator. The slipstream may be mixed with a fresh water feed stream, a portion of the rich MEG feed stream, or some combination of the two. The rich MEG feed stream also may be split into two streams, with a portion of the stream being heated and routed to the flash separator and the other portion being combined as above with the removed slipstream. The process can be performed on the slipstream after dilution and prior to entering the precipitator or after being loaded into the precipitator. Removal of the insoluble salts may be done in either a batch or continuous mode.

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Номер записи: 32
12-02-2015 дата публикации

METHOD FOR RECOVERING LITHIUM CARBONATE

Номер: US20150044124A1
Автор: Haavanlammi Liisa, TIIHONEN Marika
Принадлежит: OUTOTEC (FINLAND) OY

A method and arrangement for recovering lithium carbonate from a raw material containing lithium, which method comprises pulping () the raw material containing lithium in the presence of water and sodium carbonate for producing a slurry containing lithium from the raw material containing lithium. After pulping the lithium-containing slurry is leached () for dissolving the lithium in the solution thus producing a solution containing lithium carbonate. After pulping and leaching the method comprises carbonating () the solution containing lithium carbonate by using carbon dioxide under atmospheric conditions for producing a solution containing lithium bicarbonate and separating () the solids form the solution. The solution containing lithium bicarbonate is purified () to produce a purified solution containing lithium bicarbonate, and recovering by crystallising () lithium carbonate from the purified lithium bicarbonate-containing solution. 1. A method for recovering lithium carbonate from a raw material containing lithium selected from a group consisting of brine , a mineral containing lithium , spodumene , petalite or lepidolite or mixtures thereof , wherein the method comprisespulping the raw material containing lithium in the presence of water and sodium carbonate for producing a slurry containing lithium,leaching the slurry containing lithium in the presence of high pressure steam for producing a solution containing lithium carbonate,carbonating the solution containing lithium carbonate by using carbon dioxide under atmospheric conditions for producing a solution containing lithium bicarbonate,separating the solids from the solution containing lithium bicarbonate by solid-liquid separation,purifying the solution containing lithium bicarbonate by ion exchange for producing a purified solution containing lithium bicarbonate, andrecovering lithium carbonate by crystallising from the purified solution containing lithium bicarbonate.2. (canceled)2. The method according ...

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Номер записи: 33
07-02-2019 дата публикации

BIOPARTICLE ISOLATION AND THERAPEUTIC APPLICATION THEREOF

Номер: US20190040093A1
Автор: Markowska Anna Irmina, Pendergrast John Stephen, Pendergrast Patrick Shannon, Pendergrast Robert Scott
Принадлежит: YMIR GENOMICS LLC

Compositions and methods for the isolation of protein-nucleic acid complexes, extracellular vesicle (EV) (e.g., microvesicles) and free nucleic acids (collectively referred to as “bioparticles”) released by mammalian cells into body fluids or cell culture media are provided. Isolated bioparticles of the current disclosure contain biomolecules that are useful as diagnostic/prognostic biomarkers or for identification of therapeutic targets (e.g., disease or disorder-associated miRNAs, circulating tumor DNA). Isolation of biomolecules results in purification and concentration. Methods for producing biofluids without detectable bioparticles, largely depleted of bioparticles, and/or possessing a reduced concentration of bioparticles compared to a biofluid starting material (collectively termed “bioparticle-depleted”) are provided. Bioparticle-depleted biofluid is useful, e.g., in experimental systems where desirable to obtain a biofluid lacking or substantially depleted of endogenous bioparticles from the source material. Non-toxic bioparticle absorbing materials (e.g., exosome-reducing materials) can also be used for prophylactic, therapeutic, validation and/or experimental purposes. 1. A method for isolating , amplifying or both isolating and amplifying cell-free nucleic acids from a liquid sample with enhanced efficiency comprising:a) obtaining a liquid sample from a subject or cell culture;b) contacting said liquid sample with a crystallizing agent under conditions suitable to allow for crystal formation, thereby creating an admixture;c) incubating said admixture for a period of time sufficient to allow for crystal formation;d) separating said admixture to obtain a particle fraction containing bioparticles; ande) isolating amplifying or both isolating and amplifying cell-free nucleic acids from the particle fraction containing bioparticles, thereby isolating, amplifying or both isolating and amplifying cell-free nucleic acids from the liquid sample with enhanced ...

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Номер записи: 34
07-02-2019 дата публикации

Method and Apparatus for Purifying a Mixture Comprising Oil and Wax

Номер: US20190040330A1
Автор: Pfeil Mathias
Принадлежит: SULZER CHEMTECH AG

The present invention relates to a method for fractionating a crude mixture comprising at least one oil and at least one wax, which comprises the following method steps: (a) carrying out a pre-fractionation stage as a layer crystallization (i) with a crude mixture comprising at least one oil and at least one wax or (ii) with a crude solvent mixture obtained by adding prior to the pre-fractionation stage at most 100% by weight of solvent relative to the weight of the crude mixture, to prepare a first fraction containing low waxy oil and a second fraction containing low oily wax, (b) carrying out a first crystallization stage including (b) a first suspension crystallization sub-stage with the first fraction containing low waxy oil to prepare a third fraction containing dewaxed oil and a fourth fraction and (b) after the first suspension crystallization sub-stage, a second suspension crystallization sub-stage with a mixture of the fourth fraction obtained in method step (b) and the second fraction containing low oily wax obtained in the pre-fractionation stage of method step (a) to prepare a fifth fraction containing slack wax and a sixth fraction. 115-. (canceled)16. A method for fractionating a crude mixture comprising at least one oil and at least one wax , which comprises the following method steps:{'b': 2', '2, '(a) carrying out a pre-fractionation stage () as a layer crystallization (i) with a crude mixture comprising at least one oil and at least one wax or (ii) with a crude solvent mixture obtained by adding prior to the pre-fractionation stage () at most 100% by weight of solvent relative to the weight of the crude mixture, to prepare a first fraction containing low waxy oil and a second fraction containing low oily wax,'}{'b': '12', '(b) carrying out a first crystallization stage () including'}{'sub': '1', 'b': '14', '(b) a first suspension crystallization sub-stage () with the first fraction containing low waxy oil to prepare a third fraction containing ...

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Номер записи: 35
16-02-2017 дата публикации

PROCESS FOR REMOVING PESTICIDES FROM GINKGO BILOBA EXTRACTS, AND EXTRACTS OBTAINABLE BY SAID PROCESS

Номер: US20170042952A1
Автор: Acerbi Mario, Arpini Sabrina, Giori Andrea, Mombelli Giacomo
Принадлежит: INDENA S.P.A.

Process for removing pesticides from extracts, which involves submitting an extract obtained by conventional methods to the following steps: 1Ginkgo biloba. Extracts obtainable according to a process for removing pesticides from extracts , obtained by conventional methods , said process comprising:{'i': Ginkgo biloba', 'ginkgo', 'ginkgo, 'a) subjecting said extracts to liquid-liquid extraction to obtain a first fraction containing terpenes and pesticides not removable with hexane, and a second fraction containing flavone glycosides;'}{'i': 'ginkgo', 'b) crystallizing the terpenes from the first fraction obtained at step a) to give a ginkgolide intermediate with a ginkgolide content of not less than 50% w/w and a residual solution;'}c) crystallizing the residual solution obtained in step b) to obtain a bilobalide intermediate with a bilobalide content of not less than 50% w/w;{'i': 'Ginkgo biloba', 'd) mixing the second fraction obtained in step a) with the ginkgolide intermediate and the bilobalide intermediate obtained at steps b) and c) thereby removing said pesticides from said extracts.'}2. The extracts as claimed in claim 1 , wherein the extraction of step a) is carried out with a water-immiscible solvent selected from esters claim 1 , chlorinated hydrocarbons claim 1 , mixtures of hydrocarbons and alcohols claim 1 , ketones and mixtures of ketones and alcohols.3. The extracts as claimed in wherein the solvent is an ester having 2 to 8 carbon atoms.4ginkgo. The extracts as claimed in wherein the crystallisation of terpenes is carried out in mixtures of water and C1-C3 alcohols.5. The extracts as claimed in wherein the crystallisation from the terpene-rich fraction of step c) is carried out in water or in a mixture of water and C1-C3 alcohols. This U.S. non-provisional application is a continuation of U.S. application Ser. No. 13/258,715 filed on Nov. 18, 2011, which is a national stage of PCT/EP2010/002046 filed on Mar. 31, 2010 which claims priority to and the ...

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Номер записи: 36
19-02-2015 дата публикации

Methods of desalination and rinsing, and systems therefor

Номер: US20150047388A1
Автор: Alexander Brodt
Принадлежит: SGBD Technologies Ltd

Desalination and rinsing methods and systems are provided, which use a liquid column to efficiently perform freeze desalination and enable recyclable washing of produced minerals or combustible material. The liquid column comprises alternating layers of water immiscible liquids and water solutions which form a vertical density gradient (discrete or continuous) and exhibit a lower freezing zone from which ice floats to an upper melting zone. Cooling of introduced upwards flowing salt solutions is carried out by a countering downwards flow of cold water immiscible liquid. The process is cyclical, involves few if any mechanical moving parts and is easily controllable and adaptable to varying desalination circumstances. Rinsing of minerals or combustible material may be integrated in the heat and matter flows of the desalination system to allow effective rinsing, desalination and recycling of the used water.

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Номер записи: 37
16-02-2017 дата публикации

METHOD FOR TREATING AN AQUEOUS SOLUTION CONTAINING DISSOLVED MATERIALS BY CRYSTALLIZATION OF CLATHRATES HYDRATES

Номер: US20170044024A1
Автор: Mottet Bruno
Принадлежит: BGH

A method is disclosed for treating an aqueous solution containing dissolved materials that are crystallisable by crystallization of clathrates hydrates of a host molecule which crystallize at atmospheric pressure at temperatures higher than the temperature of ice crystallization. This method allows purified water and solid materials or solutions which are highly concentrated in dissolved materials to be produced simultaneously. The disclosure also relates to the implementation of this method. 1. A method for treating an aqueous solution containing dissolved materials that are able to crystallize or precipitate , by crystallization of clathrates hydrates of a host molecule which crystallize at atmospheric pressure at temperatures higher than the temperature of ice crystallization , said clathrates hydrates being less dense than said aqueous solution containing dissolved materials , wherein the following steps are carried out:{'b': '1', 'a) the aqueous solution is cooled, in first cooling means, to a temperature T that is higher than the temperature of ice crystallization and lower than the crystallization temperature Teq of the clathrates hydrates, and this cooled aqueous solution is introduced into a thermally insulated reactor;'}{'b': '2', 'b) a quantity of the host molecule is added into the reactor containing the cooled aqueous solution, such that the temperature T of the aqueous solution remains, following this addition and following the exothermic release due to the crystallization of the clathrates hydrates, lower than the temperature Teq, whereby the clathrates hydrates of the host molecule crystallize homogeneously in all of the volume of the aqueous solution by forming a suspension of clathrates hydrates crystallized in an aqueous solution concentrated in dissolved materials that may further contain crystallized or precipitated dissolved materials;'}c) the suspension formed during step b) is sampled in the reactor, and said suspension is sent to a decanter ...

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Номер записи: 38
16-02-2017 дата публикации

DEWATERING PROCESS THROUGH FORWARD OSMOSIS USING DEEP EUTECTIC SOLVENTS WITH OR WITHOUT DISPERSED MAGNETIC NANOPARTICLES AS NOVEL DRAW SOLUTIONS

Номер: US20170044030A1
Автор: ALAMARU Venkata Rami Reddy, BHATT Jitkumar, MAHTO Ashesh, Mondal Dibyendu, NATARAJ Sanna Kotrappanavar, POLISETTI Veera Babu, Prasad Kamalesh
Принадлежит: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH

The present invention relates to a novel forward osmosis (FO) process for dewatering of a variety of feed solution using low water activity and high osmotic pressure deep eutectic solvent with and without dispersed magnetic nanoparticles as draw solution. In particular, choline chloride-ethylene glycol, choline chloride-glycerol, FeOdispersed in former and latter were utilized as draw solution in FO for one step desalination of brackish and seawater, water recovery from effluent of leather and dye industries, protein and DNA concentration at room temperature. Owing to very low freezing point, the diluted draw solution after FO was recovered through phase separation by chilling at Ca. −10 ° C. with concomitant production of usable water. Although the present invention focused on specific DES and dispersion of FeOas magnetic nanoparticles but use of other DES having high osmotic pressure and low freezing point and other magnetic nanoparticles dispersion are logical extension of present invention. 1. A dewatering process using sustainable deep eutectic solvents (DES) with or without magnetic nanoparticles dispersion as. draw solutions through forward osmosis (FO) comprising the steps;(i) preparing a deep eutectic solvent (DES) by adding choline chloride in ethylene glycol or glycerol in 1:2 molar ratio to obtain a mixture and heating the mixture at a temperature in the range of 70° to 90° C.;(ii) optionally dispersing 0.5 to 1% iron oxide based magnetic nano/particles in the above solvents as obtained in step (i);(iii) utilising the solvent obtained in steps (i) or (ii) respectively as a draw solution in a membrane based forward osmosis (PO) processes to drive efficient dewatering of different feed solutions at room temperature and pressure in the range of 0-1 bar;(iv) freezing the diluted draw solution obtained after step (iii) at a temperature in the range of −4 to −10° C. to recover potable water and draw solution; and(v) reusing the recovered draw solution obtained ...

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Номер записи: 39
23-02-2017 дата публикации

Energy Efficient Fractionation Process for Separating the Reactor Effluent from TOL/A9+ Transalkylation Processes

Номер: US20170050901A1
Автор: Jeffrey AMELSE
Принадлежит: BP Corp North America Inc

Processes and apparatus are disclosed for the energy efficient separation of the effluent from a TOL/A9+ transalkylation reactor. The apparatus includes a reboiled prefractionation column and a sidedraw tower that produces: 1) an overhead stream including unreacted toluene, 2) a stream including unreacted C9+ aromatics, a portion of which stream may be recycled to the reactor; and 3) a sidedraw stream including C8 aromatics that may be directed to a crystallization or selective adsorption paraxylene separation unit for recovery o a paraxylene product.

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Номер записи: 40
10-03-2022 дата публикации

Recrystallization Water Treatment System and Heat-Exchange Devices (Embodiments) for Its Implementation

Номер: US20220073374A1
Автор: BLINOV Denis Dmitrievich, MURINSKIY Evgeniy Yurievich
Принадлежит: LLC PRISTINAM

The present invention relates to treatment systems for polluted and sea water by recrystallization and may be used in everyday life, the food industry, in the catering business and healthcare. 1. Recrystallization water treatment system that contains at least two heat-exchange devices with chambers for water freezing and ice melting , cooling and heating components , a water circulation loop , which is connected with the chambers of the heat-exchange devices capable of draining pre-treated water from one chamber and supplying it to another one for final treatment; a refrigerant circulation loop connected with cooling and heating components capable of alternating water freezing and ice melting steps in chambers of the heat-exchange devices and transfer of the heat of the refrigerant formed in the chamber during water freezing into the ice melting chamber; and the control and monitoring tool connected with the water and refrigerant circulation loops and capable of reversing water and refrigerant streams during alternating water freezing and ice melting steps; thereat , the water circulation loop contains a tool for the initial water supply , a tool for draining polluted water concentrate , a tool for draining pre-treated water , a tool for draining treated water , a pure water tank , and the tank for polluted water concentrate; while the refrigerant circulation loop contains a compressor , a water-cooled condenser that exchanges heat with the tank for polluted water concentrate after its draining from heat-exchange chambers , and two heat exchangers; wherein heat-exchange devices are cascaded one under another , and each device contains one chamber with the possibility to divide it into intercommunicated cooling and recirculation cavities; and to circulate water between the said cavities forming equipotential surfaces in the cooling cavity during water freezing; the refrigerant circulation loop contains an additional air-cooled condenser , the inlet and outlet of ...

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Номер записи: 41
03-03-2016 дата публикации

Crystallized hydroquinone and methods of making

Номер: US20160060196A1
Автор: Kyle Irion, Michael Joseph Stoltz, Richard S. Lott, Venkateswarlu Bhamidi
Принадлежит: Eastman Chemical Co

Crystallized hydroquinone particles and methods for making the same are provided. Cooling profiles applied during crystallization of the hydroquinone from solution may be optimized to provide crystallized particles having suitable properties and that exhibit reduced agglomeration tendencies, even after long periods of time and/or transportation over long distances.

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Номер записи: 42
08-03-2018 дата публикации

Process for making solid particles

Номер: US20180065073A1
Автор: Geoffrey Marc Wise, Ioannis Constantine Constantinides
Принадлежит: Procter and Gamble Co

The invention relates to a process of creating particles of controlled size by creating them in the interstitial regions in a continuous liquid phase that contains a second, inert gas phase at high volume fraction; namely a foam. The second phase creates a physical barrier that limits the aggregation of formed particles beyond the size of the narrow interstitial regions occupied by the continuous phase. This technique is useful when the particles normally create large aggregates due to the fast nature of the reaction and the strong attractions between the formed particles, and for enhancing the deposition of high-value materials by connecting them to coacervates of controlled size.

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Номер записи: 43
11-03-2021 дата публикации

Carbon dioxide extraction processes, devices, methods, and systems

Номер: US20210069610A1
Автор: John A. Pierce
Принадлежит: Alden Botanica LLC

A CO 2 extraction process for cannabis sativa that uses liquid CO 2 in combination with co-solvent admixtures to purify cannabis botanicals in high yield and purity. The extraction process allows for multiple extractions, or washes, to be performed with the same solvent CO 2 , which may be seamlessly recycled and purified between subsequent extraction cycles. A variety of in-line filtration vessels, pumps, vacuums, and controllable valves are used to yield a pure product while allowing a high level of user control over the process.

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Номер записи: 44
15-03-2018 дата публикации

VACUUM FILTER SYSTEM FOR SOLID-LIQUID SEPARATION AND PROCESS FOR FILTERING SOLID PARTICLES

Номер: US20180071667A1
Автор: Baniassadi Mohammad Hossein
Принадлежит:

A filter system for filtering solids includes a filtration tank for receiving a slurry containing the solids to be filtered. A filter assembly including a plurality of filter cells each having a filter medium at an exterior and a cavity at an interior is lowered into the filtration tank using a transport device carrying the filter assembly. A vacuum transfer system is connected to the filter assembly so as to transfer a vacuum to an interior of the filter cells. The vacuum transfer system is operable to perform the filtering and to retain the filtered solids while the transport device moves the filter assembly relative to the filtration tank. 1. A filter system for filtering solids , the filter system comprising:a filtration tank for receiving a slurry containing the solids to be filtered;a filter assembly including a plurality of filter cells each having a filter medium at an exterior and a cavity at an interior;a transport device carrying the filter assembly; anda vacuum transfer system connected to the filter assembly so as to transfer a vacuum to an interior of the filter cells,wherein the vacuum transfer system is operable to perform the filtering and to retain the filtered solids while the transport device moves the filter assembly relative to the filtration tank.2. The filter system according to claim 1 , wherein the vacuum transfer system is moveable with the filter assembly and includes a driven mobile pipe and a stationary pipe to transfer the vacuum to the filter cells.3. The filter system according to claim 1 , further comprising a wash tank claim 1 , the vacuum transfer system being continuously operable as the transport device moves the filter assembly from the filtration tank to the wash tank to retain the solids and to perform washing on the solids in the wash tank.4. The filter system according to claim 3 , further comprising a vacuum separator connected to a vacuum source having at least two chambers connected to the vacuum transfer system so as to ...

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Номер записи: 45
07-03-2019 дата публикации

PROCESS TO RECOVER AMMONIUM BICARBONATE FROM WASTEWATER

Номер: US20190071338A1
Автор: BASSANI Dominic, ORENTLICHER Morton, PAGANO Stephen, Simon Mark M.
Принадлежит: BION ENVIRONMENTAL TECHNOLOGIES, INC.

The present invention is a process, a method, and system for recovery and concentration of dissolved ammonium bicarbonate from a wastewater containing ammonia (NH3) using gas separation, condensation, and crystallization, each at controlled operating temperatures. The present invention includes 1) removal of ammonia from waste (sludges, semi-solids, and solids and liquids) without the use of chemicals at a temperature of at least 80 degrees Celsius, 2) condensing the gaseous containing ammonia, carbon dioxide and water vapor to remove water vapor concentrating the amount of gaseous ammonia and carbon dioxide, 3) concentrating the ammonia and carbon dioxide in the water by established means, such as concentrating the gas using partial condensation followed by passing the concentrated gas through an absorption column at a temperature of between about 20 and 50 degrees Celsius to form dissolved ammonium carbonate and ammonium bicarbonate, or total condensation followed by dewatering using reverse osmosis, and 4) crystallizing concentrated dissolved ammonium carbonate and ammonium bicarbonate at a temperature of less than about 35 degrees Celsius to form solid ammonium bicarbonate and ammonium carbonate. 1. A process to treat livestock waste containing ammonia nitrogen comprising:treating livestock waste at a temperature of at least 80 degrees Celsius to create a gas and, without the use of chemicals, converting substantially all ammonia in the waste to gaseous form in the gas, said gas also containing carbon dioxide and water vapor;treating said gas containing gaseous ammonia, carbon dioxide, and water vapor, using partial condensation to concentrate the ammonia and carbon dioxide followed by absorption of the concentrate gases, or total condensation of said gas followed by dewatering using Reverse Osmosis, or a combination of these methods; all without the use of chemical(s) and remove from said gas a significant amount of water vapor in liquid condensate form, ...

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Номер записи: 46
12-06-2014 дата публикации

SYSTEM AND METHOD FOR HYDRATE-BASED DESALINATION

Номер: US20140158635A1
Автор: Katyal Amit
Принадлежит:

The present invention relates to systems and methods for desalinating and/or treating polluted water. More particularly, the present invention relates to systems and methods for desalinating and/or treating polluted water using gas hydrates. In particular, the system comprises a desalination tank configured to form gas hydrates using a suitable hydrate former taken from a storage tank that is operatively connected to the desalination tank. With all operations, including formation of gas hydrates, discharging of highly saline water, washing the gas hydrates and dissociation of gas hydrates being conducted in a single pressurized tank such as the desalination tank, the present apparatus provides a simple and efficient solution at a low manufacturing and operating cost. 125-. (canceled)26. A method of desalinating or treating saline or polluted water up to maximum possible levels of salinity up to eutectic saline composition of water using a hydrate former under controlled temperature and pressure conditions , comprising the steps of:pumping feed water into a desalination tank from feed water tank;forming gas hydrates in said desalination tank of said feed water using said hydrate former;discharging concentrated saline water from the bottom outlet of said desalination tank to a saline water tank;washing said gas hydrates to remove surface salt; anddissociating said gas hydrates to give desalinated water and said hydrate former;wherein all the above steps are carried out in said desalination tank, and wherein said method is carried out in a batch mode, and wherein said hydrate former is stored in a storage tank and transferred to said desalination tank during gas hydrate formation.27. The method of claim 26 , wherein said storage tank receives said hydrate former back from the desalination tank during hydrate dissociation because of pressure differential between said tanks and wherein said hydrate former is selected from the group comprising of C-Chydrocarbons claim 26 ...

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Номер записи: 47
02-04-2015 дата публикации

LIQUID DESALINATION DEVICE

Номер: US20150089962A1
Автор: WANG Chin-Wen
Принадлежит:

A liquid desalination device includes an ice maker, a rotary tank, an impurities collection tank and a desalination collection tank. The ice maker has a freezer module, a liquid inlet and an ice outlet. The liquid inlet and the liquid outlet correspond to the freezer module in position. The rotary tank has a tank body with a plurality of through holes, an ice inlet and an egress. The ice inlet and the egress are located at two end of the tank body. The ice inlet corresponds to the ice outlet in position. The impurities collection tank is disposed around the tank body, and corresponding to the through holes in position. The desalination collection tank corresponds to the ice outlet in position. 1. A liquid desalination device comprising:an ice maker, having a freezer module, a liquid inlet and an ice outlet, wherein the liquid inlet and the liquid outlet correspond to the freezer module in position;a rotary tank, having a tank body with a plurality of through holes, an ice inlet and an egress, wherein the ice inlet and the egress are located at two end of the tank body, and the ice inlet corresponds to the ice outlet in position;an impurities collection tank, disposed around the tank body, and corresponding to the through holes in position; anda desalination collection tank, corresponding to the ice outlet in position.2. The liquid desalination device of claim 1 , wherein the freezer module further comprises at least one thermoelectric cooling chip claim 1 , an ice grid frame claim 1 , at least one vapor chamber claim 1 , a cooling pipe and a drip tube claim 1 , the thermoelectric cooling chip has a heat absorber side and a heat emitter side claim 1 , the ice grid frame has a plurality of grids corresponding to the heat absorber side claim 1 , the vapor chamber and the cooling pipe abut against the heat emitter side claim 1 , and the drip tube connects the liquid inlet and located over the ice grid frame.3. The liquid desalination device of claim 2 , wherein the ...

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Номер записи: 48
31-03-2016 дата публикации

Fluid processing method

Номер: US20160089641A1
Автор: Masakazu Enomura
Принадлежит: M Technique Co Ltd

A fluid processing method with which processing properties of fluids to be processed can be effectively controlled. Processing surfaces which are capable of being brought closer to each other and being separated from each other, and which rotate relatively are provided. A fluid to be processed is made to pass from inside to outside in a processing area between the processing surfaces to obtain a fluid thin film, and the resultant fluid thin film of the fluid to be processed is subjected to processing. Processing properties are controlled by changing the ratio of the distance to an outer peripheral end from a centre of rotation.

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Номер записи: 49
19-03-2020 дата публикации

VACUUM FILTER SYSTEM FOR SOLID-LIQUID SEPARATION AND PROCESS FOR FILTERING SOLID PARTICLES

Номер: US20200086250A1
Автор: Baniassadi Mohammad Hossein
Принадлежит:

A method for filtering solids from a slurry includes placing a filter assembly into a filtration tank containing the slurry. The filter assembly includes a plurality of filter cells each having a filter medium at an exterior and a cavity at an interior. The solids are filtered by moving the slurry through the filter mediums into the interiors of the filter cells to form a filter cake at the exteriors of the filter cells. The filter assembly is moved while applying a vacuum to the interiors of the filter cells through a vacuum transfer system including a mobile part and a stationary part. The mobile part moves along with the filter assembly and is sealed with respect to the stationary part. 1. A method for filtering solids from a slurry , the method comprising:placing a filter assembly into a filtration tank containing the slurry, the filter assembly including a plurality of filter cells each having a filter medium at an exterior and a cavity at an interior;filtering the solids by moving the slurry through the filter mediums into the interiors of the filter cells to form a filter cake at the exteriors of the filter cells; andmoving the filter assembly while applying a vacuum to the interiors of the filter cells through a vacuum transfer system including a mobile part and a stationary part, the mobile part moving along with the filter assembly and being sealed with respect to the stationary part.2. The method according to claim 1 , wherein the filtering is performed by applying a vacuum to the interiors of the filter cells through the vacuum transfer system claim 1 , and wherein the stationary part of the vacuum transfer system is connected to a vacuum separator which receives filtrate claim 1 , the vacuum separator being a closed cavity connected at an upper region to a vacuum pump.3. The method according to claim 1 , wherein the filter assembly is moved at least in a horizontal direction claim 1 , and wherein the mobile part of the vacuum transfer system is a mobile ...

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Номер записи: 50
12-05-2022 дата публикации

METHODS FOR CONTROLLING CRYSTALLIZATION BASED ON TURBIDITY AND SYSTEMS THEREFOR

Номер: US20220143527A1
Автор: Nagy Zoltan, Wu Wei-Lee
Принадлежит:

Methods and systems for forming crystallized products from solutions. Such a method includes depositing an input material in a solvent mixture comprising a solvent and an anti-solvent, increasing the temperature of the solvent mixture with the input material therein to an elevated temperature for a period of time sufficient to fully dissolve the input material in the solvent mixture to form a solution of the material, and performing a series of temperature cycles on the solution to produce a crystallized product from the material in the solution. The solution is alternated between heating cycles and cooling cycles based on the turbidity of the solution, and the solution is filtered to remove and collect the crystallized product therefrom. 1. A method comprising:depositing an input material in a solvent mixture comprising a solvent and an anti-solvent;increasing the temperature of the solvent mixture with the input material therein to an elevated temperature for a period of time sufficient to fully dissolve the input material in the solvent mixture to form a solution of the material;performing a series of temperature cycles on the solution to produce a crystallized product from the material in the solution, wherein the solution is alternated between heating cycles and cooling cycles based on the turbidity of the solution; andfiltering the solution to remove and collect the crystallized product therefrom.2. The method of claim 1 , wherein the turbidity of the solution is continuously determined using one or more in-line process analytical technology (PAT) tools.3. The method of claim 1 , wherein the turbidity of the solution is continuously determined using image-based analysis.4. The method of claim 3 , wherein the image-based analysis is performed with a probe-based video microscope used to continuously capture high resolution images of the solution.5. The method of claim 1 , further comprising initiating a heating cycle in response to the turbidity reaching or ...

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Номер записи: 51
05-04-2018 дата публикации

Crystal of reduced glutathione

Номер: US20180094025A1
Автор: Akihiro Fujimoto, Hiroshi Nagano, Hiroshi Ooshima, Kazunari Fukumoto, Kenta FUKUMOTO (deceased), Koichi Igarashi, Tomoya Yokoi
Принадлежит: Kyowa Hakko Bio Co Ltd, OSAKA CITY UNIVERSITY

The present invention provides a crystal of reduced glutathione that is stable, and is easy to process, and a method for producing the crystal. According to the present invention, a crystal of a metal salt of reduced glutathione is produced by suspending an amorphous solid of a metal salt of reduced glutathione in a hydrophobic organic solvent, and adding water to the resulting suspension to precipitate a crystal of a metal salt of reduced glutathione.

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Номер записи: 52
06-04-2017 дата публикации

A Modular Sub-Unit for a Suspension Crystallization System and a Suspension Crystallization Process Using Said Modular Sub-Unit

Номер: US20170095752A1
Автор: Jansen Halbe Anne
Принадлежит: SULZER CHEMTECH AG

A modular sub-unit for the production of crystals in a suspension crystallization system is disclosed comprising: a first crystallization segment , at least one further crystallization segment , a first mixing segment , optional further mixing segments , an inlet cap , an outlet cap , wherein the inlet cap and outlet cap are in fluid communication with any crystallization segments () and any mixing segments () present within the sub-unit ; and a central rotating axis for providing mechanical energy to the crystallization segments () and preferably the mixing segments (). The crystallization segments present in the sub-unit are separated from each other by means of a mixing segment. The present invention also relates to a suspension crystallization system comprising said sub-unit and a suspension crystallization process making use of said sub-unit 115-. (canceled)16. A modular sub-unit for the production of crystals in a suspension crystallization system , said sub-unit comprising: a first inlet,', 'a cooling means for cooling a slurry at a cooled surface to promote crystal formation and growth,', 'a crystal-growing volume sufficient for the growth of said crystals,', 'a mechanical scraping means for scraping the cooled surface and/or mixing a layer adjacent to the cooled surface together with a bulk of the slurry,', 'a first outlet,, 'a first crystallization segment having a second inlet,', 'a mechanical mixing means for mixing the slurry from the crystallization segment and/or reducing the size of any crystal agglomerations, if present,', 'a second outlet,, 'a first mixing segment havingwherein the crystallization segment and the mixing segment are in fluid communication with each other by means of the first outlet of the crystallization segment and the second inlet of the mixing segment,an inlet cap comprising a main supply conduit for the sub-unit and having a third outlet,an outlet cap comprising a main discharge conduit for the sub-unit and having a third inlet ...

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Номер записи: 53
14-04-2016 дата публикации

NOVEL MATERIAL MADE OF URANIUM, GADOLINIUM AND OXYGEN AND USE THEREOF AS CONSUMABLE NEUTRON POISON

Номер: US20160104548A1
Автор: DESGRANGES Lionel, Matheron Pierre, PIECK Dario, PONTILLON Yves
Принадлежит:

The present invention relates to a novel material made of uranium, gadolinium and oxygen, having a crystalline phase having cubic crystallographic structure, having an atomic ratio Gd/[Gd+U] of 0.6 to 0.93, the uranium being present in an oxidation state of +IV and/or +V. The invention further relates to the use of such a material as a consumable neutron poison of a fuel element. 1. A material based on uranium (U) , gadolinium (Gd) and oxygen (O) exhibiting a crystalline phase with a crystallographic structure of cubic type , with a Gd/[Gd+U] atomic ratio between 0.6 and 0.93 , the uranium being present therein in the +IV and/or +V oxidation state.2. The material as claimed in claim 1 , exhibiting a crystalline phase referred to as cubic 1 phase claim 1 , the Gd/[Gd+U] atomic ratio of which is between 0.79 and 0.93.3. The material as claimed in claim 2 , in which the crystallographic structure of cubic type exhibits a unit cell para parameter between 10.8 and 10.9 Å.4. The material as claimed in claim 1 , exhibiting a crystalline phase referred to as cubic 2 phase claim 1 , the Gd/[Gd+U] atomic ratio of which is between 0.6 and 0.71.5. The material as claimed in the preceding claim 4 , in which the crystallographic structure of cubic type exhibits a unit cell parameter between 5.3 and 5.5 Å.6. The material as claimed in of two-phase type claim 1 , exhibiting (i) a cubic 1 phase claim 1 , the Gd/[Gd+U] atomic ratio of which is between 0.79 and 0.93 claim 1 , and (ii) a cubic 2 phase claim 1 , the Gd/[Gd+U] atomic ratio of which is between 0.6 and 0.71.7. The material as claimed in claim 1 , in which the uranium is uranium isotopically enriched in U claim 1 , uranium isotopically depleted in U or natural uranium.8. The material as claimed in in which the gadolinium is natural gadolinium or gadolinium isotopically modified in its Gd/Gdand/or Gd/Gdratio.9. A process for the preparation of a material defined according to claim 1 , comprising a stage of sintering claim 1 ...

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Номер записи: 54
08-04-2021 дата публикации

METHOD OF RETROFITTING A SYSTEM FOR RECOVERING PARAXYLENE

Номер: US20210101853A1
Автор: Benjamin Brian
Принадлежит:

A method for retrofitting a system for recovering paraxylene. The system is retrofitted with a pressure swing adsorption unit and a second isomerization reactor. The retrofit lowers the variable cost of the plant, while providing the opportunity to maintain existing equipment and furnace and refrigeration duty. 1. A method comprising ,retrofitting a system for recovering paraxylene, the system comprising an inlet adapted to introduce an aromatic hydrocarbon feed stream to a fractionation zone, the fractionation zone adapted to separate a C8-rich aromatic hydrocarbon stream from C7− aromatic hydrocarbons and C9+ aromatic hydrocarbons, a crystallization zone adapted to form a paraxylene-rich product stream and a paraxylene-lean stream from the C8-rich aromatic hydrocarbon stream and to recover a paraxylene product, an isomerization zone adapted to isomerize at least a portion of the metaxylene and orthoxylene in the paraxylene-lean stream to form an effluent having a paraxylene concentration higher than a paraxylene concentration of the paraxylene-lean stream, the isomerization zone effluent being introduced into the fractionation zone;said retrofitting comprising adding a pressure swing adsorption zone and a secondary isomerization zone to the system such that at least a portion of the C8-rich aromatic hydrocarbon stream is fed to the pressure swing adsorption zone to form a paraxylene-rich intermediate stream and a second paraxylene-lean stream, the paraxylene-rich intermediate stream being fed to the crystallization zone and the second paraxylene-lean stream being fed to the secondary isomerization zone, the isomerate from the secondary isomerization zone having a concentration of paraxylene higher than the concentration of paraxylene in the second paraxylene-lean stream and being fed to the fractionation zone.2. The method of claim 1 , wherein the retrofitting of the system increases the amount of paraxylene product recovered without increasing the throughput of ...

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Номер записи: 55
02-06-2022 дата публикации

PROCESS FOR MAKING DRUG CRYSTALS OF DESIRED SIZE DISTRIBUTION AND MORPHOLOGY

Номер: US20220168665A1
Автор: GAINES Michael, GOUDARZI Azadeh, LOSS Troy, MALONE Amanda, STETSKO Gina
Принадлежит:

Provided herein includes a process for forming drug crystals of narrow size distribution and desire dimensions and morphology, the process includes a recrystallization step followed by a resizing step. 1. A process for providing crystals of desired size distribution and morphology , the process comprising:providing recrystallized columnar crystals having aspect ratios of large than 1 and less than 20, the aspect ratio of a given columnar crystal being the ratio of a longest dimension along a lengthwise axis relative to a shortest dimension of a transverse plane perpendicular to the lengthwise axis; andsizing the recrystallized columnar crystals to provide a collection of sized crystals having target dimensions, wherein the sizing includes segmenting at least a portion of the recrystallized columnar crystals along the respective lengthwise axes while retaining the dimensions of the transverse plane perpendicular to the lengthwise axis.2. The process of wherein the recrystallized columnar crystals further meet one or more of the following criteria:(i) 90% of the recrystallized columnar crystals by mass are no larger than 1200 microns;(ii) 50% of the recrystallized columnar crystals by mass are less than 350±180 microns;(iii) no more than 10% of the recrystallized columnar crystals by mass are less than 50 microns; and(iv) 75% or more of a total amount by volume of the recrystallized columnar crystals have an aspect ratio of 1-5.3. The process of wherein the recrystallized columnar crystals further meet one or more of the following criteria:(i) 50% of the recrystallized columnar crystals by mass are in the range of 80 to 600 microns;(ii) 75% of the recrystallized columnar crystals by mass are in the range of 50 to 800 microns; and(ii) 90% of the recrystallized columnar crystals by mass are in the range of 20 to 1100 microns.4. The process of wherein the collection of the sized crystals meet one or more of the following target dimensions:(i) 90% of the sized crystals by ...

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Номер записи: 56
13-05-2021 дата публикации

ZERO LIQUID DISCHARGE EUTECTIC FREEZE DESALINATION WITH INTERMEDIATE COLD LIQUID

Номер: US20210139346A1
Автор: Cai Jie, Parthasarathy Ramkumar N., Shabgard Hamidreza
Принадлежит: The Board of Regents of the University of Oklahoma

A method for desalinating a brine includes the use of a cooled intermediate-cold-liquid (ICL), which combines with the brine in a crystallization or freezing tank to produce a slurry of ice, brine, and ICL. The method includes steps for separating the ICL, ice and brine, and returning the separated ICL to the source of cooled ICL tank. The method concludes with the steps of passing the separated brine to the crystallization tank, and melting the separated ice to form desalinated water. The method is significant in that it produces desalinated liquid water and solid salts. The combination of superior heat transfer with high quality purified water and competitive desalination economy makes the disclosed freeze desalination technology an attractive solution for desalination of highly concentrated brines produced in a variety of industries, including but not limited to the oil and gas industry and reject brine management. 1. A method for desalinating a feed brine using a single-stage freezing process , wherein the feed brine includes a salt dissolved in water , the method comprising the steps of:providing a source of cooled intermediate-cold-liquid (ICL);introducing the feed brine and the cooled ICL to a crystallization tank;contacting the feed brine with the ICL for a time sufficient to form a slurry of ice, brine, and ICL;separating the ICL, ice and brine;returning the separated ICL to the source of cooled ICL tank;passing the separated brine to the crystallization tank; andmelting the separated ice to form desalinated water.2. The method of claim 1 , wherein the step of separating the ICL claim 1 , ice and brine comprises using a primary separator to separate the ICL claim 1 , ice and brine.3. The method of claim 2 , wherein the ice and brine are separated from the ICL and brine in a primary separator and wherein the ice is separated from the brine in an ice-brine separator.4. The method of claim 3 , wherein the ICL is separated from brine in an ICL-brine separator.5 ...

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Номер записи: 57
09-04-2020 дата публикации

RECOVERING A CAUSTIC SOLUTION VIA CALCIUM CARBONATE CRYSTAL AGGREGATES

Номер: US20200109059A1
Автор: Fessler Eric, Heidel Kenton Robert, Keith David William, Ritchie Jane Anne, Vollendorf Nicholas
Принадлежит:

Techniques for growing crystalline calcium carbonate solids such that the crystalline calcium carbonate solids include a volume of 0.0005 mmto 5 mm, include a slaker to react quicklime (CaO) and a low carbonate content fluid to yield a slurry of primarily slaked lime (Ca(OH)); a fluidized-bed reactive crystallizer that encloses a solid bed mass and includes an input for a slurry of primarily slaked lime, an input for an alkaline solution and carbonate, and an output for crystalline calcium carbonate solids that include particles and an alkaline carbonate solution; a dewatering apparatus that includes an input coupled to the crystallizer and an output to discharge a plurality of separate streams that each include a portion of the crystalline calcium carbonate solids and alkaline carbonate solution; and a seed transfer apparatus to deliver seed material into the crystallizer to maintain a consistent mass of seed material. 1. A method for growing crystalline calcium carbonate solids in the presence of an alkaline carbonate solution in a fluidized-bed reactive crystallizer the method comprising:{'sub': '2', 'reacting, in a slaking process, quicklime (CaO) and a low carbonate content fluid to yield a slurry of primarily slaked lime (Ca(OH));'}introducing the slurry of primarily slaked lime and an alkaline solution comprising between 0.1M to 4.0 M hydroxide and between 0.1 M to 4.1M carbonate into a fluidized-bed reactive crystallizer comprising a bed of solid particles flowing the slurry of primarily slaked lime and the alkaline solution through the fluidized-bed reactive crystallizer to fluidize the bed of solid particles, the slurry of primarily slaked lime and the alkaline solution having a fluidization flow velocity within a range of 2 m/h to 70 m/h;{'sub': 2', '3, 'reacting the Ca(OH)slurry and the alkaline carbonate solution to deposit a portion of precipitated calcium carbonate (CaCO) onto the bed of solid particles; and'}discharging a portion of the bed of solid ...

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Номер записи: 58
03-05-2018 дата публикации

PRODUCTION METHOD FOR CONCENTRATED PRODUCT USING FREEZE-CONCENTRATION METHOD

Номер: US20180116235A1
Автор: Ichimura Takefumi, Kamiya Tetsu, Kashiwagi Kazunori, MATSUBARA Hiroki, Omori Toshihiro, Satake Yoshinori
Принадлежит: Meiji Co., Ltd.

Provided is a production method for a concentrated product, using a freeze-concentration method having a high yield rate (low loss rate) that is practically applicable, as required in large-scale (commercial scale) production. The production method for concentrated product using the freeze-concentration method includes: an ice crystal generation step in which a fluid to be treated is cooled, ice crystals of the fluid are generated in the fluid, and a mixed fluid to be treated is formed wherein the mixed fluid to be treated is comprised of the ice crystals and a concentrated fluid produced from the fluid to be treated by generating the ice crystals in the fluid thereby the fluid is concentrated; and an ice crystal separation step in which the mixed fluid is separated into the concentrated fluid to be treated and the ice crystals, and the separated concentrated fluid be treated is retrieved. 1. A method for producing concentrated products using a freeze-concentration method , which comprises:an ice crystal generation step in which a fluid to be treated is cooled, ice crystals of said fluid are generated in said fluid, and a mixed fluid to be treated is formed wherein said mixed fluid to be treated is comprised of said ice crystals and a concentrated fluid produced from said fluid to be treated by generating said ice crystals in said fluid thereby said fluid is concentrated; andan ice crystal separation step in which said mixed fluid is separated into said concentrated fluid to be treated and said ice crystals, and said separated concentrated fluid be treated is retrieved.2. The method for producing concentrated products using a freeze-concentration method as defined in claim 1 , wherein said step of forming said mixed fluid composed of said ice crystals and said concentrated fluid produced from said fluid to be treated by concentrating said fluid claim 1 , and said step of separating said mixed fluid into said concentrated fluid to be treated and said ice crystals and ...

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Номер записи: 59
05-05-2016 дата публикации

PROCESS FOR SIMULTANEOUS EXTRACTION AND SEPARATION OF ESTERIFIED AND UNESTERIFIED MONOHYDROXYCAROTENOIDS

Номер: US20160122268A1
Автор: KHACHIK Frederick
Принадлежит:

The present invention is in the field of organic and natural product chemistry. The present invention relates to an efficient process for purification, simultaneous extraction, and separation of monohydroxycarotenoids from dihydroxycarotenoids in various natural products or in synthetic mixtures. Similarly, the process can also be applied to the simultaneous extraction, saponification, and separation of esterified mono- and dihydroxycarotenoids in natural products and their oleoresins or in their synthetic mixtures. Therefore, esterified and unesterified monohydroxycarotenoids such as (3R)-β-cryptoxanthin and (3R,6′R)-α-cryptoxanthin can be efficiently separated from their corresponding dihydroxycarotenoids such as (3R,3′R,6′R)-lutein and (3R,3′R)-zeaxanthin that are found in various plants or in synthetic mixtures. 1. A method of at least partially separating at least one monohydroxycarotenoid ester from at least one dihydroxycarotenoid ester , comprising continuously extracting the at least one monohydroxycarotenoid ester from a mixture of the at least one monohydroxycarotenoid ester and the at least one dihydroxycarotenoid ester with an alcohol to give an alcoholic solution enriched in the at least one monohydroxycarotenoid ester.2. The method of claim 1 , further comprising concentrating the alcoholic solution to give a residue enriched in the at least one monohydroxycarotenoid ester.3. The method of claim 2 , wherein the at least one monohydroxycarotenoid ester residue is subjected to further continuous extraction with an alcohol to give an alcoholic solution enriched in the at least one monohydroxycarotenoid ester.4. The method of claim 3 , further comprising concentrating the alcoholic solution to give a residue further enriched in the at least one monohydroxycarotenoid ester.5. The method of claim 4 , further comprising subjecting the residue further enriched in the at least one monohydroxycarotenoid ester to saponification to give an at least one ...

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Номер записи: 60
16-04-2020 дата публикации

CONTINUOUS CRYSTALLIZATION METHOD UNDER CONTROL OF MULTISTAGE MEMBRANE

Номер: US20200114277A1
Автор: HE Gaohong, JIANG Xiaobin, LI GUANNAN, LI Xiangcun, LU Dapeng, TUO Linghan, WU Xuemei, XIAO Wu
Принадлежит:

The present invention provides a continuous crystallization method under control of the multistage membrane modules, and belongs to the technical field of crystallization engineering. A crystallization solution is added to a crystallizer, and a stirring apparatus and a temperature control apparatus are started. After the system running stability, the loop of crystallization is started. Meanwhile, the coolant or antisolvent feed liquid loop is also started. The crystallization solution can respectively conduct crystal nucleation, growth and ripening in the multistage membrane modules, and then the crystallization solution is transported into a filter device and a drying apparatus to obtain the final crystal products. The desired crystal products can be obtained by the systematical control of the nucleation and crystal growth through the flow and the temperature of the crystallization solution, coolant or antisolvent feed liquid, and the contact time between two liquid phases. 1. A continuous crystallization method under control of multistage membrane , wherein a continuous crystallization apparatus is composed by two loops;a first loop: a first stirring apparatus is installed in a crystallizer with a jacket; the jacket is connected with a first temperature control apparatus through a pipeline; an outlet of the crystallizer is connected with a lower port of a first membrane module in a membrane module combination successively through a first peristaltic pump, a first rotameter, a first valve, a first thermometer and a first pressure gauge; one path of an upper port of a last membrane module in the membrane module combination is connected with an inlet of the crystallizer through a seventh valve; another path of the upper port of the last membrane module in the membrane module combination is connected with a filter device through a third valve; an upper port of the filter device is connected with an inlet of the crystallizer, and a lower port of the filter device is ...

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Номер записи: 61
25-08-2022 дата публикации

Process for producing 4,4'-dichlorodiphenyl sulfone

Номер: US20220267261A1
Автор: Christian Schuetz, Frauke THRUN, Indre THIEL, Jessica Nadine Hamann, JUN Gao, Stefan Blei
Принадлежит: BASF SE

The invention relates to a process for producing 4,4′-dichlorodiphenyl sulfone, comprising: (I) reacting thionyl chloride, chlorobenzene and aluminum chloride forming an intermediate reaction product and hydrogen chloride; (II) mixing aqueous hydrochloric acid and the intermediate reaction product to obtain an organic phase comprising 4,4′-dichlorodiphenyl sulfoxide and an aqueous phase; (III) cooling the organic phase to a temperature below the saturation point of 4,4′-dichlorodiphenyl sulfoxide to obtain a suspension; (IV) solid-liquid-separation of the suspension to obtain crystallized 4,4′-dichlorodiphenyl sulfoxide, and mother liquor; (V) washing the crystallized 4,4′-dichlorodiphenyl sulfoxide with a carboxylic acid to obtain carboxylic acid-wet 4,4′-dichlorodiphenyl sulfoxide; (VI) reacting the washed 4,4′-dichlorodiphenyl sulfoxide and an oxidizing agent in a carboxylic acid as solvent to obtain a reaction mixture comprising 4,4′-dichlorodiphenyl sulfone and carboxylic acid; (VII) separating the reaction mixture comprising 4,4′-dichlorodiphenyl sulfone and carboxylic acid into a residual moisture comprising 4,4′-dichlorodiphenyl sulfone as crude product and a liquid phase comprising carboxylic acid.

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Номер записи: 62
31-07-2014 дата публикации

Thermoelectric device with make-before-break high frequency converter

Номер: US20140208773A1
Автор: Gerald Philip Hirsch, Jon Murray Schroeder
Принадлежит: Individual

An improved circular multi-element semiconductor thermoelectric hybrid utilizes a make-before-break high frequency switching output component to provide nominal alternating current voltage outputs. Overall efficiency of heat conversion is improved by coupling a chiller to the thermoelectric generator where exhaust heat produces chilled liquid or air that is conveyed to the cold side of the thermoelectric device. The thermoelectric generator is used in a variety of transportation vehicles including manufactured vehicles, retrofitted vehicles and vehicle power combinations.

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Номер записи: 63
17-05-2018 дата публикации

SYSTEMS AND METHODS FOR SEPARATING SOLUBLE SOLUTIONS

Номер: US20180134579A1
Автор: JR. William H., Mitchell
Принадлежит:

A system for separating a soluble solution includes a first freezer configured to receive a liquid feed stream and a refrigerant stream, and discharge a concentrated solution stream, wherein the first freezer is configured to exchange heat between the liquid feed stream and the refrigerant stream through direct contact within the first freezer and freeze a portion of the liquid feed stream, a first separator external to the first freezer and configured to separate ice particles from the concentrated solution stream and recirculate the concentrated solution stream to the first freezer, and a first ice washer coupled to the first separator and configured to receive the ice particles separated from the concentrated solution stream by the first separator and wash the separated ice particles to free the ice particles from contaminants. 1. A system for separating a soluble solution , comprising:a first freezer configured to receive a liquid feed stream and a refrigerant stream, and discharge a concentrated solution stream, wherein the first freezer is configured to exchange heat between the liquid feed stream and the refrigerant stream through direct contact within the first freezer and freeze a portion of the liquid feed stream;a first separator external to the first freezer and configured to separate ice particles from the concentrated solution stream and recirculate the concentrated solution stream to the first freezer; anda first ice washer coupled to the first separator and configured to receive the ice particles separated from the concentrated solution stream by the first separator and wash the separated ice particles to free the ice particles from contaminants.2. The system of claim 1 , further comprising a perforated plate disposed in the first freezer and configured to disperse the refrigerant stream into droplets within the first freezer with a plurality of holes extending through the perforated plate claim 1 , each hole comprising a first aperture having a ...

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Номер записи: 64
18-05-2017 дата публикации

COMPOSITIONS FOR ENHANCING PRODUCTION OF ALUMINUM HYDROXIDE IN AN ALUMINUM HYDROXIDE PRODUCTION PROCESS

Номер: US20170137298A1
Автор: "OBrien Kevin", Liu Jianjun
Принадлежит:

Compositions and methods used in the modification of crystallization of aluminum hydroxide from liquor in an aluminum hydroxide production process, such as the Bayer process. More particularly, crystal growth modifier compositions comprising a component of crude corn oil derived from a bioethanol production process and/or a component of biodiesel and methods of using such compositions to modify particle size and distribution of precipitated alumina trihydrate in a precipitation liquor crystallization process. 2. The liquor crystallization composition of claim 1 , wherein the crystal growth modifier composition comprises the crude corn oil component claim 1 , the crude corn oil component comprising{'sub': 16', '18, '80 percent or more by weight mono alkyl esters, including Cand Cethyl esters, diglycerol esters and triglycerol esters of long chain fatty acids; and'}0-15 percent by weight free fatty acids.3. The liquor crystallization composition of claim 2 , the crystal growth modifier composition comprising 98-100 percent by weight of the crude corn oil component.4. The liquor crystallization composition of claim 2 , wherein the crystal growth modifier composition consists essentially of the crude corn oil component and the carrier liquid claim 2 , wherein the hydrocarbon liquid is a hydrocarbon oil comprising aliphatic or aromatic oil compounds chosen from the group consisting of paraffinic oils claim 2 , naphthenic oils claim 2 , mixed paraffinic and aromatic oils claim 2 , the residue of Calcohol distillation claim 2 , and mixtures thereof.5. The liquor crystallization composition of claim 1 , wherein the crystal growth modifier composition comprises the biodiesel component claim 1 , the biodiesel component comprising 90 percent by weight or more C claim 1 , Cor Cmethyl esters and 0-2 percent by weight free fatty acids.6. The liquor crystallization composition of claim 5 , wherein the crystal growth modifier composition comprises 98-100 percent by weight of the ...

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Номер записи: 65
10-06-2021 дата публикации

Diamond pressure apparatus for crystallizing cannabinoids

Номер: US20210170301A1
Автор: Adam Weiss, Josh Rutherford, Spencer Uniss, Stephen Tolpa
Принадлежит: Individual

An apparatus for purifying diamond CBD oil crystals. A cylindrical glass or metal vessel is provided and supported by least one support post, the vessel having an upper portion and a lower surface having laser etched nucleation sites for initiating crystal growth. A removable head is engageable with the upper portion of the vessel, the head having an uppermost portion and a plurality of ports extending therethrough. A pressurized nitrogen tank is operatively connected to a port of the head, as is a pressure gauge. A safety valve is disposed at the uppermost portion of the head. Optionally, an inline desiccant chamber is also operatively connected to the head. The apparatus crystalizes cannabinoids in either a solventless process or a solvent process.

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Номер записи: 66
28-05-2015 дата публикации

Method of detoxifying asbestos by using room-temperature recrystallization scheme

Номер: US20150148583A1
Автор: Myung-Kyu Lee, Soo-Chun Chae, Young-Nam JANG
Принадлежит: Korea Institute of Geoscience and Mineral Resources KIGAM

Disclosed is a method of detoxifying asbestos by using a room-temperature recrystallization scheme. The method includes heat-treating a rock or slate containing asbestos; and putting the heat-treated rock or slate in an aqueous solution, to which organic acid is added, to allow the heat-treated rock or slate to react with the aqueous solution having the organic acid.

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Номер записи: 67
14-08-2014 дата публикации

Clathrate desalination process using an ultrasonic actuator

Номер: US20140223958A1
Автор: McCormack Richard A., Ripmeester John A.
Принадлежит:

A freeze desalination process uses cyclopentane (“CH”) (14) as an agent for the formation of a gas hydrate as a clathrate (13). A crystallizer vessel (10) containing a mixture of seawater (11) and diffuse bubbles (18) of CHis cooled to allow a gas hydrate phase to form. An ultrasonic transducer (21) located in the bubble stream encourages nucleation and thus clathrate formation. 1. A method for desalination of water comprises:providing an amount of seawater;cooling said amount to a phase which allows for clathrate formation;injecting a dispersed clathrate-forming gas agent into said amount;imparting ultrasonic energy into said amount;collecting clathrate crystals from said amount; and,melting said crystals to form an amount of fresh water.2. The method of claim 1 , which further comprises augmenting said amount with a flow of additional seawater.3. The method of claim 1 , wherein said injecting occurs through a gas diffuser to create a stream of bubbles of said gas agent.4. The method of claim 1 , wherein said imparting comprises locating and activating an ultrasonic transducer within said amount.5. The method of claim 3 , wherein said imparting comprises locating and activating an ultrasonic transducer within said stream.6. The method of or claim 3 , wherein said activating comprises operating said transducer at a frequency of between about 30 and 50 Kilohertz.7. The method of claim 3 , which further comprises placing an amount of solid material particles within said stream.8. The method of claim 7 , wherein said solid material particles comprises silica gel particles.9. The method of claim 7 , wherein said imparting comprises locating and activating an ultrasonic transducer within said stream; and claim 7 , wherein said method further comprises:carrying said particles within a structure mounted to said transducer; wherein said structure comprises an array of apertures sized and shaped to contain said particles and allow passage of a portion of said stream ...

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Номер записи: 68
24-05-2018 дата публикации

NANO SEEDING TOOLS TO GENERATE NANOMETER SIZE CRYSTALLIZATION SEEDS

Номер: US20180140969A1
Автор: Calero Guillermo A.
Принадлежит: University of Pittsburgh - of the Commonwealth System of Higher Education

A kit and a method for using the kit to generate nanoseeds from protein nanocrystals and aggregates is disclosed. The method comprises mixing a plurality of beads with a protein nanocrystal or aggregate, and agitating the mixture to generate the nanoseeds. Nanoseeds made by disclosed embodiments may be of a high quality, as evaluated by TEM, and can be used to produce high quality protein crystals. Additionally, spectroscopic techniques, such as UV fluorescence and/or brightfield microscopy can be used to identify aggregates suitable to produce nanoseeds. 1. A kit , comprising:a container selected from a tube or a flask; anda plurality of beads, each bead independently having a bead diameter suitable to be effective to make seed crystals from at least one protein nanocrystal.2. The kit of claim 1 , wherein each bead independently has a bead diameter of from 0.05 mm to 1.5 mm.3. The kit of claim 1 , wherein each bead independently has a bead diameter of from 0.1 mm to 1 mm.4. The kit of claim 2 , wherein each bead independently has a bead diameter of less than 0.5 mm.5. The kit of claim 2 , wherein each bead independently has a bead diameter selected from 0.1 mm claim 2 , 0.5 mm claim 2 , or 1 mm.6. The kit of claim 1 , wherein the plurality of beads comprises glass beads claim 1 , metal beads claim 1 , metal alloy beads claim 1 , ceramic beads claim 1 , PTFE beads claim 1 , or a combination thereof.7. The kit of claim 1 , wherein the plurality of beads comprises glass beads claim 1 , stainless steel beads claim 1 , or a combination thereof.8. The kit of claim 1 , wherein the plurality of beads comprises beads having a mixtures of diameters.9. The kit of claim 1 , wherein the plurality of beads comprises beads of the same diameter.10. The kit of claim 1 , wherein the tube is a microcentrifuge tube.11. The kit of claim 10 , wherein the microcentrifuge tube has a size of from 0.5 mL to 2 mL.12. The kit of claim 11 , wherein the microcentrifuge tube is a 1.5 mL ...

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Номер записи: 69
24-05-2018 дата публикации

WATER DESALINATION SYSTEM AND METHOD FOR FAST COOLING SALINE WATER USING FAST FREEZE PROCESS

Номер: US20180141826A1
Автор: Hammer Kimberly Nicole, Lissianski Vitali Victor
Принадлежит:

A desalinating system and process is disclosed. The desalination system comprises using a freeze or fast-cooling process to freeze saline water droplets in a controlled manner that provides for diffusion of salt ions to a center of each frozen saline water droplet and formation of salt crystals surrounded by pure water crystals. The pure water crystals and salt crystals are subsequently separated in an ice melter using heat exchange to form a pure water stream. 1. A system for desalination comprising:a feed source of saline water;a feed source of at least one refrigerant;a compressor, comprising an input fluidly coupled to the source of said at least one refrigerant and an output, and configured to generate a compressed vaporized refrigerant;a condenser comprising an input fluidly coupled to the compressor and a plurality of outputs, said condenser operatively configured to simultaneously melt frozen saline water droplets and generate a chilled, partially liquefied refrigerant stream;at least one expansion device comprising at least one input fluidly coupled to the condenser and at least one output configured to release a chilled refrigerant stream at a refrigerant stream injection velocity;a freezing chamber comprising at least one input to introduce the chilled refrigerant stream into the freezing chamber, and a first and second output; andat least one injector configured to introduce the saline water into the freezing chamber in the form of saline water droplets to freeze the saline water droplets,wherein one or more parameters relative to the saline water droplets and the chilled refrigerant stream provide for a controlled freezing of the saline water droplets to promote salt ions in the saline water droplets to diffuse towards a center of each of the frozen saline water droplets and form a plurality of salt crystals in a center of each frozen saline water droplet surrounded by a plurality of ice crystals comprising pure water.2. The system of claim 1 , wherein ...

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Номер записи: 70
24-05-2018 дата публикации

Method and Apparatus for Purifying a Mixture Comprising Oil and Wax

Номер: US20180142169A1
Автор: Pfeil Mathias
Принадлежит: SULZER CHEMTECH AG

The present invention relates to a method for fractionating a crude mixture comprising at least one oil and at least one wax, which comprises the following steps: (a) mixing the crude mixture with a solvent to obtain a crude solvent-mixture, (b) carrying out at least one crystallization stage with the solvent-mixture obtained in step (a) to prepare a first fraction containing dewaxed oil and a second fraction containing slack wax, (c) carrying out at least one crystallization stage with the second fraction obtained in step (b) in a layer crystallizer, wherein to the second fraction prior to the crystallization in step (c) no solvent or at most 100% by weight of solvent relative to the weight of the second fraction are added, to prepare a third fraction containing hard wax having an oil content of at most 1.5% by weight and a fourth fraction containing soft wax having an oil content of more than 1.5% by weight and (d) circulating at least a part of the fourth fraction into at least one of the at least one crystallization stage of step (b). 114-. (canceled)15. A method for fractionating a crude mixture comprising at least one oil and at least one wax , which comprises the following steps:(a) mixing the crude mixture with a solvent to obtain a crude solvent-mixture,(b) carrying out at least one crystallization stage with the solvent-mixture obtained in step (a) to prepare a first fraction containing dewaxed oil and a second fraction containing slack wax,(c) carrying out at least one crystallization stage with the second fraction obtained in step (b) in a layer crystallizer, wherein to the second fraction prior to the crystallization in step (c) no solvent or at most 100% by weight of solvent relative to the weight of the second fraction are added, to prepare a third fraction containing hard wax having an oil content of at most 1.5% by weight and a fourth fraction containing soft wax having an oil content of more than 1.5% by weight and(d) circulating at least a part of ...

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Номер записи: 71
04-06-2015 дата публикации

Removal of Ferric Iron as Hematite at Atmospheric Pressure

Номер: US20150152519A1
Автор: Aguilar Renato Antonio Loaiza, De Hoyos Ruben Rangel, Liu Houyuan, Rodríguez Carolina Isabel Meneses
Принадлежит: BHP Billiton SSM Development Pty Ltd

A process for the removal of ferric iron as hematite from a nickel solution containing ferric and ferrous ions including the steps of: raising the temperature of the nickel solution to between 90° C. and the boiling point of the solution at atmospheric pressure; raising the pH of the nickel solution to be between 2 and 3; and adding a hematite seed to facilitate hematite precipitation, wherein ferric ions are precipitated as hematite in a predominantly crystalline form. 2. A process according to wherein the pH is raised by adding to the nickel solution a neutralizing agent wherein the neutralizing agent is limestone or saprolite.3. A process according to wherein the neutralizing agent is saprolite and the hematite seed is added at a dose of at least a weight ratio of 1:1 to the added saprolite.4. A process according to wherein limestone is used as the neutralizing agent and the hematite seed is added at a dose of 1:1 to at least 3:1 to the hematite formed during ferric ion precipitation.5. A process according to wherein the neutralizing agent is limestone which is added is in a ratio of 1:1 to 1:1.3 of the stoichiometric weight of the precipitated ferric ions.6. A process according to wherein nickel is recovered from the solution predominantly free of ferric ions claim 1 , in an ion exchange (IX) step to produce a nickel concentrated IX eluate claim 1 , and an IX raffinate containing cobalt and rejected impurities.7. A process according to wherein the IX step uses an IX resin selected from a resin having a bis-picolylamine chelating resin or iminodiacetate chelating resin.8. A process according to wherein nickel and cobalt is recovered from the solution predominantly free of ferric ions in a solvent extraction (SX) process to produce a nickel and cobalt concentrated eluate claim 1 , and an SX raffinate containing ferrous ions claim 1 , chromium claim 1 , aluminum claim 1 , manganese and magnesium.9. A process according to wherein cobalt is recovered from the IX ...

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Номер записи: 72
16-05-2019 дата публикации

RECOVERY OF LACTOSE FROM AN AQUEOUS SOLUTION

Номер: US20190144955A1
Автор: van Spronsen Jacob
Принадлежит:

The invention is directed to a method for recovering lactose from an aqueous lactose solution comprising a concentration step, wherein water is removed from the aqueous lactose solution by freezing out water at a temperature below the eutectic temperature of the aqueous lactose solution and at a lactose concentration higher than the eutectic concentration of the aqueous lactose solution, thereby obtaining a concentrated lactose solution; and a crystallization step, wherein at least part of the concentrated lactose solution is subjected to crystallization at a temperature above the eutectic temperature of the concentrated lactose solution, thereby obtaining lactose crystals. 1. A method for recovering lactose from an aqueous lactose solution , the method comprising:a) concentrating the aqueous lactose solution, wherein water is removed from the aqueous lactose solution by freezing out water at a temperature below the eutectic temperature of the aqueous lactose solution and at a lactose concentration higher than the eutectic concentration of the aqueous lactose solution, thereby obtaining a concentrated lactose solution; andb) crystallizing the lactose, wherein at least part of the concentrated lactose solution is subjected to crystallization at a temperature above the eutectic temperature of the concentrated lactose solution, thereby obtaining lactose crystals.2. The method according to claim 1 , wherein the water is removed from the aqueous lactose solution at a lactose concentration higher than 15 wt. % claim 1 , preferably higher than 25 wt. % claim 1 , based on the total weight of the aqueous solution.3. The method according to claim 1 , wherein the water is removed from the aqueous lactose solution by cooling to a temperature that lies 1-20° C. claim 1 , preferably 1-15° C. claim 1 , more preferably 2-10° C. below the eutectic temperature of the aqueous mixture.4. The method according to claim 1 , wherein the crystallization of the lactose in (b) is conducted at ...

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Номер записи: 73
07-05-2020 дата публикации

Process for preparing bortezomib, intermediates, and crystalline forms thereof

Номер: US20200140464A1
Автор: Hsing Yu Chang, Shen Han Yang, Vallapa Soong, Wei-Hong Tseng
Принадлежит: Pharmacore Biotech Co Ltd

The present disclosure provides a process for preparing Bortezomib, intermediates, and crystalline forms thereof.

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Номер записи: 74
28-08-2014 дата публикации

Process of purifying a residue with calcium ions

Номер: US20140238942A1
Автор: Emeline Gravier, Francis Grosjean, Frederic Nicolas, Jean-Yves SEGUIN
Принадлежит: SOLVAY SA

The present invention relates to a process of purifying a residue from an industrial process using calcium ions to obtain a purified brine, comprising: (a) mixing the residue comprising sulfate salts from the industrial process with calcium salts; (b) separating insoluble species and/or precipitates from the suspension from (a); (c) adding one or more selected from C0 2 , carbonates, bicarbonates, hydrogen carbonates or fluorinated salts into the filtrate from (b) to remove excess calcium ions; and (d) separating precipitates from the suspension from (c) to obtain a purified brine. Strontium and/or barium salts, which typically exist in the residue, may also be removed from the residue by using the present process. According to the present method, calcium ions are effectively removed from the brine. Thus, a deposition of calcium ions on devices, which are used in the further processes such as crystallization or electrolysis, can be avoided. At the same time, the amount of barium and strontium ions in the brine is reduced significantly. As such, the purified brine can be simply achieved with high purity and low cost in an industrial scale.

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Номер записи: 75
22-09-2022 дата публикации

Continuous-Flow, Well Mixed, Microfluidic Crystallization Device for Screening Polymorphs, Morphologies and Crystallization Kinetics at Controlled Supersaturation

Номер: US20220297027A1
Автор: Coliaie Paria, Singh Meenesh R.
Принадлежит:

The disclosure relates to a microfluidic system for the screening of polymorphs, morphology, and crystallization kinetics under well-mixed, continuous-flow at controlled supersaturations. The disclosure also relates to a method for screening crystalline polymorphs and morphology, and crystallization kinetics. The microfluidic system includes a microfluidic chamber having one or more inlets, a passive mixing zone, and a trap zone. The passive mixing zone promotes mixing of solvent, solute, and optionally antisolvent under stable, controlled levels of supersaturation. The trap zone similarly has stable, controlled levels of supersaturation and correspondingly low velocity to retain solute crystals formed in the trap zone for time-dependent evaluation. 1. A microfluidic system comprising: (i) a first inlet zone in fluid communication with a first inlet adapted to receive a first fluid stream comprising a solute dissolved in a solvent,', '(ii) optionally a second inlet zone in fluid communication with a second inlet adapted to receive a second fluid stream,', '(iii) a passive mixing zone having (A) a first mixing zone boundary and (B) a second mixing zone boundary separate from the first mixing zone boundary, the passive mixing zone being in fluid communication with the first inlet zone via the first mixing zone boundary and, when present, the second inlet zone via the first mixing zone boundary,', '(iv) a trap zone having a trap zone boundary in fluid communication with the second mixing zone boundary, wherein the trap zone is positioned within the microfluidic chamber such that fluid flowing through the microfluidic chamber has a sufficiently low velocity to retain solute crystals formed in the trap zone within the trap zone,', '(v) an outlet zone in fluid communication (A) with the passive mixing zone via the first mixing zone boundary, and (B) an outlet adapted to discharge fluid from the microfluidic chamber, and', '(vi) optionally a first temperature control means ...

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Номер записи: 76
24-06-2021 дата публикации

SOLID-LIQUID DISTRIBUTION DETECTING APPARATUS

Номер: US20210190732A1
Автор: KONISHI Nobuyuki
Принадлежит:

It is an object of the present invention is to obtain a solid-liquid distribution detecting apparatus that detects solid-liquid distribution in a solid-liquid separation column. A solid-liquid distribution detecting apparatus () of the present invention detects solid-liquid distribution of a content in a solid-liquid separation column () of a freeze concentration device and includes a sound source () that emits a sound wave to the column surface of the solid-liquid separation column (), a measuring device () that measures a resonance waveform on the surface of the column, and an analysis device () that analyzes the resonance waveform measured by the measuring device () and determines a solid-liquid distribution state of the content in the solid-liquid separation column based on the analysis result. 1. A solid-liquid distribution detecting apparatus for detecting solid-liquid distribution of a content in a solid-liquid separation column of a freeze concentration device , the solid-liquid distribution detecting apparatus comprising:a sound emitting unit adapted to emit a sound wave to a column surface of the solid-liquid separation column;a measurement unit adapted to measure a resonance waveform on the column surface;an analysis unit adapted to analyze the resonance waveform measured by the measurement unit; anda determination unit adapted to determine a solid-liquid distribution state of the content in the solid-liquid separation column based on an analysis result obtained by the analysis unit.2. The solid-liquid distribution detecting apparatus according to claim 1 , wherein the determination unit compares a specific resonance waveform preset according to vibration characteristics of the content that contacts an interior of the solid-liquid separation column with the resonance waveform of the sound wave analyzed by the analysis unit and determines a solid-liquid distribution state of the content in the solid-liquid separation column.3. The solid-liquid distribution ...

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Номер записи: 77
14-06-2018 дата публикации

Saline Water Desalination, Concentration, and Crystallization

Номер: US20180162758A1
Автор: Cantrell Ben Harrison
Принадлежит:

This invention obtains fresh water and only solid waste from input saline water. This result is commonly known as desalination having zero liquid discharge (ZLD). The current common means of ZLD desalination is to use any common desalination process such as distillation, reverse osmosis, electrodialysis, etc. followed by brine recovery and crystallization which are both based on evaporation of water processes. This invention provides an alternative to the commonly used brine recovery and crystallization processes to produce only solid waste. This invention has major components of (a) new ion concentration process, (b) combinations of prior art desalination processes and new ion concentration processes to produce fresh water and nearly saturated saline water from a saline water input, (c) another combination of prior art desalination and new ion concentration processes to produce fresh water and supersaturated saline water having a salinity in the metastable state zone from a nearly saturated saline water input, and (d) a separate process that precipitates out solids from the supersaturated saline water after seed crystals are introduced. The process also provides a means that prevents long-term buildup of precipitated solids in the ion concentration process that supersaturates the nearly saturated saline water input. The ion concentration process is composed of variations of prior art ion transfer processes where electrodialysis and capacitive deionization are examples. 16-. (canceled)7. A saline water desalination and concentration process composed of:a. any deionization devise such as electrodialysis, capacitive deionization, and capacitive electrodialysis that transfers ions between two independent saline waters which can greatly increase the salinity of one of the saline waters and reduce the salinity of the other saline water where it's significant property is that it can highly concentrate the one saline water and leave the other saline water with lower but ...

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Номер записи: 78
30-05-2019 дата публикации

Demilitarization and disposal of hc smoke ordinance

Номер: US20190160391A1
Автор: John Potee Whitney
Принадлежит: Individual

Demilitarization and disposal of HC smoke ordnance with recovery of constituents thereof as commodities entails mechanically removing from the ordnance a filler comprising hexachloroethane, zinc oxide and grained aluminum; heating the filler to a temperature above the sublimation temperature of hexachloroethane but safely below the temperature at which hexachloroethane chemically decomposes, and draining and collecting the dense hexachloroethane vapor; and conventionally separating the aluminum from the zinc oxide. Filler is supplied to and removed from a heating compartment from above; hexachloroethane drains via a lower portion of the heating compartment.

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Номер записи: 79
01-07-2021 дата публикации

Method for producing menthol particles stabilized against caking, and storage-stable menthol particles and use thereof

Номер: US20210198169A1
Автор: Gerd Tebben, Gunnar Heydrich, Matthias Rauls, Sebastian WLOCH
Принадлежит: BASF SE

The present invention relates to a process for producing menthol particles stabilized against caking, wherein menthol particles are, following shaping, stored for at least 7 days at a temperature of 0 to 30° C., after which the menthol particles are supplied with a minimum input of mechanical energy. The present invention further relates to storage-stable menthol particles and to the use of said menthol particles in household and consumer goods of all kinds.

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Номер записи: 80
21-06-2018 дата публикации

SYSTEM AND METHODS FOR REMOVING IMPURITIES FROM PHOSPHOGYPSUM AND MANUFACTURING GYPSUM BINDERS AND PRODUCTS

Номер: US20180170766A1
Автор: DASHEVSKY Boris, KOSSON David Samuel, KOVLER Konstantin, RECHES Yonathan
Принадлежит:

Methods and systems that remove impurities from phosphogypsum (PG), including from radium and heavy metal salts, and produce gypsum binders and products. In one embodiment, PG is reacted with a chloride solution in an acidic environment under mechanical manipulation and/or heat followed by galvanic and/or zeolite absorption removal of impurities. 1. A system for removing impurities from phosphogypsum (PG) , the system comprising:a ball drum mill configured to maintain: (a) a temperature between about 85 to about 150° C.; and (b) reacting a concentrated chloride solution and PG to produce a PG reaction slurry;a reaction pool configured for configured to: (a) maintain a temperature between about 85 to about 150° C.; and (b) dehydrating said PG reaction slurry, wherein the reaction pool is in fluid connection with the ball drum mill;a filter configured to separate a solid fraction containing an alpha-hemihydrate gypsum crystal from a liquid waste fraction of said PG reaction slurry, wherein the filter is in fluid connection with the reaction pool, wherein the filter is configured to maintain temperature of the solid and liquid fractions; anda neutralization mixer configured for mixing the solid fraction with calcium oxide to neutralize the solid fraction, wherein the neutralization mixer is in fluid connection with the filter and wherein the neutralization mixer is configured to maintain temperature of the solid fraction.2. The system of claim 1 , wherein the reaction pool further comprises a cathode and an anode for galvanic removal of impurities from the PG reaction slurry.3. The system of claim 1 , further comprising a scrubber configured for purifying vapors produced in the ball drum mill claim 1 , wherein the scrubber is in fluid connection with the ball drum mill.4. The system of claim 1 , further comprising a neutralization pool configured for mixing lime and/or carbonate powder with contents received from the scrubber claim 1 , wherein the neutralization pool ...

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Номер записи: 81
02-07-2015 дата публикации

Crystallization device

Номер: US20150182873A1
Автор: Yoshikazu Kato
Принадлежит: HADO CO Ltd, Satake Chemical Equipment Mfg Ltd

To provide a crystallization device with a simple structure and high classification performance in crystallization at a center part of an upper part in a vertical container having a classification leg on a bottom portion, rotor blade unit for generating a swirling flow of a raw material liquid of a suspension slurry in the container along an inner circumferential surface of the container is provided, and at a center part on a bottom surface of the container, liquid-flow direction changing unit for causing the raw material liquid to flow upward at the center part of the container is provided, and the liquid-flow direction changing unit is formed of baffles, each being made of a band-shaped plate, provided radially on the bottom surface.

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Номер записи: 82
28-05-2020 дата публикации

Production of Mogroside Compounds in Recombinant Hosts

Номер: US20200165652A1
Автор: Houghton-Larsen Jens
Принадлежит:

The invention relates to recombinant microorganisms and methods for producing mogroside compounds and mogroside precursors. 1. A recombinant host cell capable of producing one or more mogroside compounds in a cell culture , the host cell comprising a recombinant gene encoding a heterologous or an endogenous polypeptide capable of deglycosylating a mogroside precursor;wherein the one or more mogroside compounds are a deglycosylation product of the mogroside precursor; andwherein expression of the gene increases production of the one or more mogroside compounds.2. The recombinant host cell of claim 1 , wherein the heterologous or the endogenous polypeptide is free of a domain facilitating secretion of the heterologous or the endogenous polypeptide from the host cell claim 1 , preferably selected from a signal peptide or a transmembrane domain.3. The recombinant host cell of or claim 1 , wherein the host cell is capable of retaining at least about 50% of an expressed heterologous or endogenous polypeptide capable of deglycosylating the mogroside precursor in a cytosol of the host cell.4. The recombinant host cell of any one of - claim 1 , wherein expression of the gene increases a cytosolic mogroside precursor deglycosylation activity of the host cell relative to a corresponding host cell lacking the gene.5. The recombinant host cell of claim 4 , wherein expression of the gene increases the cytosolic mogroside precursor deglycosylation activity of the host cell by at least about 10% relative to the corresponding host cell lacking the gene.6. The recombinant host cell of any one of - claim 4 , wherein expression of the gene increases the cytosolic mogroside precursor deglycosylation activity of the heterologous or the endogenous polypeptide comprising the host cell relative to the corresponding host cell lacking the gene.7. The recombinant host cell of claim 6 , wherein expression of the gene increases the cytosolic mogroside precursor deglycosylation activity of the ...

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Номер записи: 83
28-06-2018 дата публикации

Semi-Continuous Crystallization Method and Apparatus

Номер: US20180179121A1
Автор: Manfred Stepanski, Mathias PFEIL
Принадлежит: SULZER CHEMTECH AG

A process for the separation of a substance from a liquid feed mixture and for the purification of the substance by fractional layer crystallization, wherein the liquid feed mixture comprises the substance to be separated and purified in a concentration of less than 50% by weight, which comprises the subsequent steps in the given order: (a) feeding the liquid feed mixture into a crystallization zone, in which at least one surface is provided, so that at least a part of the surface contacts the liquid feed mixture, (b) cooling the at least one surface of the crystallization zone to a temperature below the equilibrium freezing temperature of the liquid feed mixture so that a crystal layer enriched in the substance to be separated and purified is deposited on the at least one cooled surface, whereby a mother liquid having a lower concentration of the substance to be separated and purified than the liquid feed mixture is formed from the liquid feed mixture, (c) removing at least a portion of the mother liquid from the crystallization zone, (d) adding a further portion of liquid feed mixture into the crystallization zone, (e) allowing further deposition of a crystal layer enriched in the substance to be separated and purified to take place on the at least one cooled surface, (f) optionally carrying out a sweating stage and removing a sweating residue and (g) melting the crystal layer to obtain the separated and purified substance.

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Номер записи: 84
18-09-2014 дата публикации

Recovering a caustic solution via calcium carbonate crystal aggregates

Номер: US20140271379A1
Автор: Arvinder Pal Singh Kainth, David William Keith, Jane Anne RITCHIE, Kenton Robert HEIDEL
Принадлежит: Carbon Engineering Ltd

Techniques for converting a portion of a carbonate to hydroxide include receiving an alkaline carbonate solution that includes between 0.1M (moles per liter of solution) to 4.0M hydroxide and between 0.1M to 4.1M carbonate; reacting, in a slaking process, quicklime (CaO) and a low carbonate content fluid to yield a slurry of primarily slaked lime (Ca(OH) 2 ); and reacting the Ca(OH) 2 slurry and the alkaline carbonate solution to grow calcium carbonate (CaCO 3 ) crystal aggregates of 0.0005 mm 3 to 5 mm 3 in volume in a fluidized-bed reactive crystallizer.

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Номер записи: 85
28-06-2018 дата публикации

METHOD FOR PURIFYING MITOMYCIN C

Номер: US20180179219A1
Автор: HOSHIKAWA Masahiro, Ishihara Shuji, Mimura Takashi, Nishimura Koichiro
Принадлежит: KYOWA HAKKO KIRIN CO., LTD.

Provided are a method for purifying mitomycin C, comprising a step of recrystallizing crude mitomycin C crystals using a high-purity methanol; mitomycin C obtainable by the method; and 1. A method for purifying mitomycin C , comprising a step of recrystallizing crude mitomycin C crystals using a high-purity methanol.2. The method according to claim 1 , wherein the high-purity methanol has a purity of 99.00 to 99.99%.3. The method according to claim 1 , wherein the high-purity methanol has a purity of 99.50 to 99.99%.4. The method according to claim 1 , wherein the high-purity methanol has a total metal concentration of 0.01 to 300 ppb.5. The method according to claim 1 , wherein the high-purity methanol has a total metal concentration of 0.01 to 100 ppb.6. The method according to claim 1 , wherein the high-purity methanol has a zinc concentration of 0.01 to 100 ppb.7. The method according to claim 1 , wherein the high-purity methanol has a zinc concentration of 0.01 to 10 ppb.8. Mitomycin C obtainable by the method according to . The present invention relates to a method for purifying mitomycin C; and the like.Mitomycin C is an antitumor antibiotic which can be obtained by culturing a strain of and is widely used clinically.Various methods for purifying mitomycin C from the culture medium harvested after the culture of the above-mentioned bacterial strain are conventionally known. For example, included are an activated carbon adsorption method which comprises adding activated carbon to the culture supernatant separated from the bacterial cells by filtration to allow mitomycin C to adsorb thereto, followed by eluting mitomycin C with an organic solvent; and a method which comprises transferring mitomycin C in the culture supernatant to an organic phase, concentrating the organic phase, purifying the mitomycin C-containing concentrate by alumina chromatography or counter current distribution, concentrating the mitomycin C-containing eluate to dryness, and adding a ...

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Номер записи: 86
18-09-2014 дата публикации

Directed nucleation and crystal growth from solution using surface energy modified amorphous materials

Номер: US20140275611A1
Автор: Andrew H. Bond, Kevin M. Schaab
Принадлежит: DENOVX LLC

A means of directing nucleation and crystal growth has been developed in which these stages of crystallization are influenced by surface energy modifications to amorphous substrates. The surface energy of a substrate can affect the contact angle, line tension, wettability and energetics of the interaction with a supersaturated solution, and these factors are important in crystallization. The use of amorphous substrates creates an opportunity to modify their surface to create useful ranges of surface energies that enhance or inhibit, as may be advantageous, the thermodynamic, kinetic, or a combination of both, factors in nucleation, crystal growth, or crystallization from a supersaturated solution.

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Номер записи: 87
05-07-2018 дата публикации

PROCESS FOR PRODUCTION OF GLYCOPYRRONIUM TOSYLATE

Номер: US20180186735A1
Автор: Molteni Renato, SHAW Anthony Adrian, Vigano Enrico
Принадлежит:

Provided herein are methods for the production of glycopyrronium tosylate and glycopyrronium tosylate compositions. Also provided herein are compositions useful in the production of glycopyrronium tosylate. Additionally provided herein are glycopyrronium tosylate compositions. Glycopyrronium tosylate is useful for the treatment of, among other conditions, hyperhidrosis. 130.-. (canceled)31. A method of producing purified glycopyrronium tosylate comprising:purifying glycopyrronium tosylate by one or more crystallizations in an aqueous solvent to obtain a purified glycopyrronium tosylate, wherein the aqueous solvent consists essentially of water.32. The method of claim 31 , wherein the aqueous solvent consists of water.33. The method of claim 31 , wherein the glycopyrronium tosylate is purified by at least two crystallizations in the aqueous solvent.34. The method of claim 31 , wherein the purified glycopyrronium tosylate is a mixture of threo-glycopyrronium tosylate and erythro-glycopyrronium tosylate claim 31 , and the threo-glycopyrronium tosylate is at least 99% of the total glycopyrronium tosylate in the mixture and the erythro-glycopyrronium tosylate is less than 1% of the total glycopyrronium tosylate in the mixture.35. The method of claim 34 , wherein the threo-glycopyrronium tosylate is at least 99.5% of the total glycopyrronium tosylate in the mixture and the erythro-glycopyrronium tosylate is less than 0.5% of the total glycopyrronium tosylate in the mixture.36. The method of claim 34 , wherein the threo-glycopyrronium tosylate is at least 99.6% of the total glycopyrronium tosylate in the mixture and the erythro-glycopyrronium tosylate is less than 0.4% of the total glycopyrronium tosylate in the mixture.38. The method of claim 37 , wherein the water-miscible organic solvent is a water-miscible aldehyde claim 37 , organic acid claim 37 , ketone claim 37 , nitrile claim 37 , diol claim 37 , alcohol claim 37 , aminoalcohol claim 37 , glycol claim 37 , ...

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Номер записи: 88
20-06-2019 дата публикации

METHOD FOR RECOVERING TITANIUM (HALO) ALKOXIDE FROM A WASTE LIQUID

Номер: US20190184306A1
Автор: Cheng Chung Ping, SCHUMANN Werner Karl, Su Jing
Принадлежит:

A method for separating one or more titanium (halo) alkoxides from a liquid mixture comprising titanium tetrachloride TiCland at least one titanium (halo) alkoxide, said method comprising: agitating and cooling the liquid mixture until crystallization of at least one titanium (halo) alkoxide occurs in the liquid mixture; separating the crystallized titanium (halo) alkoxide from the mixture; and optionally, washing the separated, crystallized titanium (halo) alkoxide with a solvent. 1. A method for separating titanium (halo) alkoxide from a liquid mixture comprising titanium tetrachloride TiCl4 and at least one titanium (halo) alkoxide , said method comprising: cooling the liquid mixture until crystallization of at least one titanium (halo) alkoxide occurs in the liquid mixture; separating the crystallized titanium (halo) alkoxide from its mother liquor by a separation equipment selected from the group of decanter , filter presses , vacuum filters , pressure filters and centrifuges; and optionally , distilling said mother liquor to separate titanium tetrachloride therefrom , wherein the titanium (halo) alkoxide is of the formula TiXx(OR)y where X is halogen , R is alkyl , x=0-3 , y=1-4 and x+y=4.2. The method according to claim 1 , wherein the crystallized titanium (halo) alkoxide is separated from its mother liquor by centrifugation.3. The method according to claim 2 , wherein a decanter centrifuge is used for separating the crystallized titanium (halo) alkoxide from its mother liquor.4. The method according to claim 1 , wherein the liquid mixture is a waste liquid resulting from production of a titanium-based olefin polymerization catalyst.5. The method according to claim 1 , wherein the liquid mixture is a waste liquid resulting from production of a titanium-based olefin polymerization catalyst claim 1 , by contacting a magnesium alkoxide or a magnesium chloride-alcohol adduct with titanium tetrachloride in the presence of a hydrocarbon reaction diluent.6. The ...

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Номер записи: 89
06-07-2017 дата публикации

WATER DESALINATION SYSTEM AND METHOD FOR FAST COOLING SALINE WATER USING TURBINES

Номер: US20170190597A1
Автор: Hofer Douglas Carl, Laursen Anna Lis, Lissianski Vitali Victor, MORAGA Francisco J., OSAHENI John Aibangbee, SINGH Rajkeshar
Принадлежит: GENERAL ELECTRIC COMPANY

A desalinating system and method is disclosed. The desalination system comprises using a turbo freeze or fast-cooling process to freeze saline water droplets and separate salt crystals from pure water crystals, wherein said system provides for simultaneous injection of saline water droplets and a chilled refrigerant into a freezing chamber at a slip velocity sufficient to reduce the size of the saline water droplets to an optimal diameter. 1. A system for desalination comprising:a feed source of saline water;a feed source of at least one refrigerant;a compressor, comprising an input fluidly coupled to the source of said at least one refrigerant and an output, and configured to generate a compressed vaporized refrigerant;a condenser comprising an input fluidly coupled to the compressor and an output, said condenser operatively configured to generate a chilled, partially liquefied refrigerant stream;at least one expansion device comprising at least one input fluidly coupled to the condenser and at least one output configured to release the chilled refrigerant stream at a refrigerant stream injection velocity;a freezing chamber comprising at least one input to introduce the chilled refrigerant stream into the chamber, and a first, second and third output,and at least one injector configured to introduce the saline water into the freezing chamber in the form of saline water droplets, wherein the at least one ejector introduces the saline water droplets into the freezing chamber at a slip injection velocity relative to the refrigerant stream injection velocity of about 10% to about 180%;and wherein direct contact in the chamber between the saline water droplets and the refrigerant stream forms ice particles comprising pure water.2. The system of claim 1 , wherein the at least one expansion device is a two-stage turbo expander.3. The system of claim 2 , wherein the turbo expander is adapted to function as the freezing chamber.4. The system of claim 2 , wherein the ...

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Номер записи: 90
11-06-2020 дата публикации

Method for the production of cannabinoids from types of industrial hemp

Номер: US20200181050A1
Автор: Barbara Febbruari, Giovanni Cipolletti, Jacopo Chini, Luana Vagnoli, Marina Matulli
Принадлежит: Inalco SpA

The present invention describes a process for the production of (−)-cannabidiol (CBD) from industrial hemp by means of an extraction followed by two alternative working processes: a process A which provides extraction with solvents first to an alkaline pH and then to acidic pH to isolate the carboxyl form of the CBD which is then subjected to decarboxylation and a process B which provides the elimination of waxes and pitches and then purification by chromatography. At the end of both alternative working processes the CBD is crystallized obtained in high purity crystalline form.

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Номер записи: 91
22-07-2021 дата публикации

DEVICE AND METHOD FOR INCREASING SOLID HOLDUP IN REACTION CRYSTALLIZER

Номер: US20210220796A1
Автор: Huang Qingshan, Xiao Hang, YANG Chao, ZHU Quanhong
Принадлежит:

A device and method for increasing solid holdup in a reaction crystallizer are disclosed. The device includes a discharge pipe, a clear liquid pipe, a clear liquid tank and a gas collecting pipe. A lower end of the discharge pipe is inserted into the crystallizer below the liquid level, while that of the clear liquid pipe is inserted into the clear liquid tank below the liquid level. By using the gas collecting pipe, the reaction crystallizer and the clear liquid tank are communicated all the time. When feeding, a liquid-solid mixture in the crystallizer automatically enters the discharge pipe and flows upward slowly therein, during which solid particles gradually settle down and automatically fall back into the crystallizer while the clear liquid keeps on flowing upward, enters the clear liquid pipe and thereby flows into the clear liquid tank. The clear liquid tank maintains a constant liquid level via overflowing. 17-. (canceled)827-. (canceled)28. A device for increasing solid holdup in a reaction crystallizer , comprising:a reaction crystallizer;a clear liquid tank;a discharge pipe having a discharge pipe first end;wherein discharge pipe first end resides in the reaction crystallizer;a clear liquid pipe having a clear liquid pipe first end and a clear liquid pipe second end;wherein the clear liquid pipe first end resides in the clear liquid tank;wherein the clear liquid pipe second end connects to the discharge pipe at a first pipe junction at a first pipe junction height, thereby allowing fluid to flow between the discharge pipe and the clear liquid pipe;a gas collecting pipe having a gas collecting pipe lower end and a gas collecting pipe intermediate region at a gas collecting pipe intermediate region height;wherein gas collecting pipe lower end communicates with the discharge pipe;wherein the gas collecting pipe intermediate region height is above the first pipe junction height; andwhereby, when a level of liquid residing in the reaction crystallizer is ...

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Номер записи: 92
22-07-2021 дата публикации

Method for Extracting Lithium from Salt Lake Brine and Simultaneously Preparing Aluminum Hydroxide

Номер: US20210221697A1
Автор: XU Xiang, XUE Duan
Принадлежит: Beijing University of Chemical Technology

The present disclosure relates to a method for extracting lithium from salt lake brine and simultaneously preparing aluminum hydroxide. This method includes: a. adding an aluminum salt to the brine to obtain a mixed salt solution A, adding an alkali solution to the mixed salt solution A for co-precipitation reaction, then subjecting to crystallization reaction and solid-liquid separation at the end of the reaction to obtain magnesium-aluminum hydrotalcite solid product and lithium-containing brine, wherein in step a, the alkali solution is an alkali solution free of carbonate ion; b. evaporating and concentrating the lithium-containing brine to obtain a lithium-rich brine, adding an aluminum salt to the lithium-rich brine to obtain a mixed salt solution B, adding an alkali solution dropwise to the mixed salt solution B to perform a co-precipitation reaction and solid-liquid separation after the end of the reaction to obtain a lithium-containing liquid and a lithium-containing layered material filter cake, wherein in step b, the alkali solution is an alkali solution free of carbonate ion; c. dispersing the lithium-containing layered material filter cake in deionized water to form a suspension slurry, then adjusting the pH value of the suspension slurry so as to carry out a lithium deintercalation reaction; d. filtering the slurry obtained after the lithium deintercalation reaction to obtain a lithium-containing solution and aluminum hydroxide filter cake; e. washing the aluminum hydroxide filter cake with deionized water and drying to obtain aluminum hydroxide solid.

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Номер записи: 93
25-09-2014 дата публикации

HIGHLY CRYSTALLIZED PARTICLES AND PRODUCTION METHOD THEREOF

Номер: US20140287232A1
Автор: NAGASHIMA Yuji, Naka Tomomichi, Tokuno Yoko
Принадлежит: KABUSHIKI KAISHA TOSHIBA

According to one embodiment, there is provided a method for producing highly crystallized particles having a specific surface area of 5 m/g or more. The raw material composition contains a resin and at least partially amorphous precursor particles. The composition is heat-treated to carbonize the resin and improve the crystallinity of the precursor particles. A mixture of highly crystallized particles and carbon is prepared. Then, a solution containing an acid is contacted with the mixture to react the acid with the carbon. The carbon is removed and a slurry containing reaction product is prepared. The highly crystallized particles include a first portion having a smaller diameter and a second portion having a larger diameter. 1. A method for producing highly crystallized particles having a specific surface area of 5 m/g or more , the method comprising:heat-treating a raw material composition that comprises a resin and at least partially amorphous precursor particles dispersed in the resin to carbonize the resin and improve the crystallinity of the precursor particles, thereby preparing a mixture of highly crystallized particles and carbon; andbringing a treatment solution comprising an acid into contact with the mixture to react the acid with the carbon and preparing a slurry comprising the highly crystallized particles from which the carbon is removed, the highly crystallized particles comprising a first portion having a smaller particle diameter and a second portion having a larger particle diameter and a product generated by the reaction remaining in the slurry.2. The method according to claim 1 , wherein the treatment solution has a pH of 1 or less.3. The method according to claim 1 , further comprising subjecting the slurry to electrolysis to remove the product.4. The method according to claim 3 , further comprising:before subjecting the slurry to the electrolysis, subjecting the slurry to centrifugation to separate the slurry into a supernatant in which the ...

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Номер записи: 94
13-07-2017 дата публикации

Crystallization methods for purification of monoclonal antibodies

Номер: US20170198028A1
Автор: Benjamin Smejkal, Bernhard Helk, Dariusch Hekmat, Henk Schulz
Принадлежит: NOVARTIS AG

This disclosure relates to methods for crystallization of antibodies from cell-free culture supernatant.

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Номер записи: 95
02-10-2014 дата публикации

METHODS AND APPARATUS FOR PRODUCTION OF NATURAL L-MENTHOL

Номер: US20140290290A1
Автор: Izukura Hideaki, Nagaoka Ryosuke, Nagaoka Yoshiyuki, Shibata Yuri, Tokita Susumu
Принадлежит:

Embodiments are provided that provide for efficient production of highly pure natural I-menthol. In some embodiments, a method for preparing natural I-menthol involves providing crude mentha oil in a crystallizer and gradually reducing the temperature of the crystallizer in a step-wise manner, thereby producing highly pure crystals in less than two weeks. The methods disclosed herein are suitable for pharmaceutical GMP. 1. A system for purifying I-menthol , comprising:a crystallizer containing crude mentha oil of plant origin;a stripping system adapted to pass a gas through the crystallizer; initiate reduction of a temperature in the crystallizer in order to reduce the temperature of the crude mentha oil from a temperature at which the crude mentha oil is a liquid to a temperature below 30° C. in a gradual manner over a period of at least 8 hours to cause I-menthol crystals to form in the crystallizer;', 'activate the stripping system in order to pass the gas over the crystals in the crystallizer to remove liquid from the crystals; and', 'initiate heating of the crystallizer in order to melt the crystals; and, 'an automated process control system comprising a processor programmed toa conduit configured to receive melted I-menthol from the crystallizer, wherein the crystallizer and the conduit together comprise a closed system that prevents contact between the content of the closed system and outside contaminants.2. The system of claim 1 , wherein the crystallizer comprises a plurality of cooling plates and/or cooling coils.3. The system of claim 2 , wherein the automated process control system independently controls the temperature for each of said plurality of cooling plates and/or cooling coils.4. The system of claim 1 , wherein the system is automated.5. The system of claim 1 , further comprising a crystal formation detector.6. The system of claim 1 , wherein the conduit is in fluid communication with a storage tank claim 1 , wherein the storage tank is part of ...

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Номер записи: 96
30-07-2015 дата публикации

FORMATION OF STABLE SUBMICRON PEPTIDE OR PROTEIN PARTICLES BY THIN FILM FREEZING

Номер: US20150209289A1
Автор: ENGSTROM Joshua, III Robert O., Johnston Keith P., Williams
Принадлежит:

The present invention includes compositions and methods for preparing micron-sized or submicron-sized particles by dissolving a water soluble effective ingredient in one or more solvents; spraying or dripping droplets solvent such that the effective ingredient is exposed to a vapor-liquid interface of less than 50, 100, 150, 200, 250, 200, 400 or 500 cmarea/volume to, e.g., increase protein stability; and contacting the droplet with a freezing surface that has a temperature differential of at least 30° C. between the droplet and the surface, wherein the surface freezes the droplet into a thin film with a thickness of less than 500 micrometers and a surface area to volume between 25 to 500 cm. 138.-. (canceled)39. A single-step , single-vial method for preparing micron-sized or submicron-sized particles comprising:reducing the temperature of a vial wherein the vial has a temperature differential of at least 30° C. between the solvent and the vial; and{'sup': −1', '−1, 'spraying or dripping solvent droplets of a water soluble effective ingredient dissolved in one or more solvents directly into the vial such that the effective ingredient is exposed to a vapor-liquid interface of less than 500 cmarea/volume, wherein the surface freezes the droplet into a thin film with a thickness of less than 500 micrometers and a surface area to volume between 25 to 500 cm.'}40. The method of claim 39 , wherein the droplets freeze upon contact with the surface in about 50 claim 39 , 75 claim 39 , 100 claim 39 , 125 claim 39 , 150 claim 39 , 175 claim 39 , 200 claim 39 , 250 claim 39 , 500 claim 39 , 1 claim 39 ,000 and 2 claim 39 ,000 milliseconds.41. The method of claim 39 , wherein the droplets freeze upon contact with the surface in about 50 to 500 milliseconds.42. The method of claim 39 , wherein the droplets freeze upon contact with the surface in about 50 to 150 milliseconds.43. The method of claim 39 , wherein the droplet has a diameter between 0.1 and 5 mm at room temperature. ...

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Номер записи: 97
27-06-2019 дата публикации

Method for refining organic compound

Номер: US20190194101A1
Автор: Hiroaki Isobe, Kousuke Niwa
Принадлежит: NGK Insulators Ltd

An organic compound refinement method for refining a specific organic compound which is a target compound from at least two types of organic compounds. The method includes separating the target compound from an organic compound other than the target compound while the at least two types of organic compounds are irradiated with light at an infrared absorption wavelength of a specific functional group that is not contained in the target compound but is contained in the organic compound other than the target compound, or separating the target compound from an organic compound other than the target compound while the at least two types of organic compounds are irradiated with light at an infrared absorption wavelength of a specific functional group that is contained in the target compound but is not contained in the organic compound other than the target compound.

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Номер записи: 98
21-07-2016 дата публикации

Novel methods for recovery of leaf proteins

Номер: US20160208236A1
Автор: Hong Fu, Martin Lo
Принадлежит: UNIVERSITY OF MARYLAND AT COLLEGE PARK

A novel method for processing soluble plant leaf proteins is described. While leaf proteins are considered potentially the most abundant source of protein in nature, the lack of efficient processing techniques for leaf proteins has limited their commercial use. The method described in this patent provides a means of extracting and purifying leaf proteins from plants which is suitable for leaf protein production on an industrial scale.

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Номер записи: 99
28-07-2016 дата публикации

PROCESS FOR PRODUCING AMMONIUM SULFATE CRYSTALS

Номер: US20160214868A1
Автор: DEBEIJ Johannes Elisabeth Pierre, Ekkelenkamp Geert, GEERTMAN Robert, Tinge Johan Thomas, VAN YSACKER Peter
Принадлежит:

The present invention provides a continuous process for producing ammonium sulfate crystals, wherein said process comprises: i) feeding to a series of crystallization sections, which crystallization sections are heat integrated in series, a solution of ammonium sulfate; ii) crystallizing ammonium sulfate crystals from said solution of ammonium sulfate; iii) purging a fraction of the solution of ammonium sulfate from each of said crystallization sections;and iv) discharging ammonium sulfate crystals from each crystallization section, characterized in that: a fraction of said solution of ammonium sulfate is purged from at least one crystallization section to at least one other crystallization section; and an apparatus suitable for producing ammonium sulfate crystals. 1. A continuous process for producing ammonium sulfate crystals , wherein said process comprises:i) feeding to a series of crystallization sections, which crystallization sections are heat integrated in series, a solution of ammonium sulfate;ii) crystallizing ammonium sulfate crystals from said solution of ammonium sulfate;iii) purging a fraction of the solution of ammonium sulfate from each of said crystallization sections; andiv) discharging ammonium sulfate crystals from each crystallization section, characterized in that:a fraction of said solution of ammonium sulfate is purged from at least one crystallization section to at least one other crystallization section.2. A process according to claim 1 , wherein the crystallization sections are heat integrated by means of steam.3. A process according to claim 2 , wherein a fraction of said solution of ammonium sulfate is purged from each crystallization section in the series to the next crystallization unit in the series claim 2 , as defined by descending temperature of steam supply claim 2 , with the exception that the purge from the final crystallization section in the series is discharged from the series.4. A process according to claim 1 , wherein each ...

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Номер записи: 100