24-02-2022 дата публикации
Номер: US20220055979A1
Принадлежит:
A method for esterification of one or more carboxylic acid groups in a compound containing one or more carboxylic acid groups wherein the esterification reagent is a diazo-compound of formula: 120.-. (canceled)22. The method of claim 21 , wherein:{'sub': S', 'S', 'S', 'S', 'S', '2', 'S', '2', 'S', 'S', 'S', 'S', 'S', '2', '2', 'S', '2', 'S', '2', 'S', '2', 'S', '2', 'S', '2', 'S', '2', 'S', 'S', 'S', '2', 'S', 'S', '2', 'S', 'S', '2', 'S', '2', '2', 'S', '2', 'S', 'S', 'S', '2', '2', 'S', 'S', '2', 'S', 'S, 'optional substitution is substitution with one or more oxo group, thioxo group, halogen, nitro, cyano, cyanate, azido, thiocyano, isocyano, isothiocyano, sulfhydryl, hydroxyl, alkyl, alkoxy, alkenyl, alkenyloxy, alkynyl, alkynyloxy, aryl, aryloxy, heteroaryl, heteroaryloxy, carbocyclyl, carbocyclyloxy, heterocyclyl, heterocyclyloxy, alkylthio, alkenylthio, alkynylthio, arylthio, thioheteroaryl, thiocarbocyclyl, thioheterocyclyl, —COR, —COH, —OCOR, —OCOH, —CO—OR, —CO—OH, —CO—O—CO—R, —CON(R), —CONHR, —CONH, —NR—COR, —NHCOR, —NHR, —N(R), —O—SO—R, —SO—R, —SO—NHR, —SO—N(R), —NR—SO—R, —NH—SO—R, —NRCO—N(R), —NH—CO—NHR, —O—PO(OR), —O—PO(OR)(N(R)), —O—PO(N(R)), —N—PO(OR), —N—PO(OR)(N(R), —P(R), —B(OH), —B(OH)(OR), or —B(OR), where each Rindependently is an alkyl, alkenyl, alkynyl, aryl, heteroaryl, carbocyclyl, or heterocyclyl group or two Rwithin the same substituent optionally together form a carbocyclic or heterocyclic ring having 3 to 10 ring atoms.'}23. The method of claim 21 , wherein Ris —CON(R′) claim 21 , where each R′ independently claim 21 , is hydrogen claim 21 , or an optionally substituted alky claim 21 , alkenyl claim 21 , alkynyl claim 21 , aryl claim 21 , alkylaryl claim 21 , or arylalkyl claim 21 , where two R′ on the same atom may together with that atom form a 5- to 8-member carbocyclic or heterocyclic ring in which one or more ring atoms can be replaced with —CO— claim 21 , —O— claim 21 , —CS— claim 21 , —S— or —NR— claim 21 , where R is hydrogen or ...
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