18-09-2014 дата публикации
Номер: US20140274790A1
Принадлежит:
Provided is a peptide that specifically or selectively binds to human IgG. This peptide comprises an amino acid sequence consisting of 13 to 17 amino acid residues and is capable of binding to human IgG, wherein the amino acid sequence is represented by formula I: (X)-C-(X)-H-R-G-(Xaa1)-L-V-W-C-(X), wherein, X each independently represents any amino acid residue except cysteine, C represents a cysteine residue, H represents a histidine residue, R represents an arginine residue, G represents a glycine residue, Xaa1 represents a glutamic acid residue or an asparagine residue, L represents a leucine residue, V represents a valine residue, and W represents a tryptophan residue. 117-. (canceled)18. A peptide comprising an amino acid sequence consisting of 13 to 17 amino acid residues , the peptide being capable of binding human IgG , wherein the amino acid sequence is represented by the following formula I:{'br': None, 'sub': 1-3', '1-3, '(X)-C-A-Y-H-R-G-E-L-V-W-C-(X)\u2003\u2003(I)'}wherein X each independently represents any amino acid residue except cysteine,C represents a cysteine residue,A represents an alanine residue,Y represents a tyrosine residue,H represents a histidine residue,R represents an arginine residue,G represents a glycine residue,E represents a glutamic acid residue,L represents a leucine residue,V represents a valine residue, andW represents a tryptophan residue.19. The peptide according to claim 18 , wherein claim 18 , when the peptide is 17 amino acid residues claim 18 , amino acid residues at positions 1 to 3 and 15 to 17 from an N terminus are each as follows:amino acid residue at position 1=S, O, F, or non-existent,amino acid residue at position 2=D, A, S, P, or non-existent,amino acid residue at position 3=S, D, T, N, E, or R,amino acid residue at position 15=S, T, or D,amino acid residue at position 16=H, G, Y, T, N, D, F, or non-existent, andamino acid residue at position 17=Y, F, H, M, or non-existent.21. The peptide according to claim 18 , ...
Подробнее
