Benzo (5,6) cyclohepta (1,2-B) pyridine derivatives for the prevention of farnesyl protein transferase.
Опубликовано: 21-08-2000
Автор(ы): G. Taveras Arthur, George Njoroge F., J. Doll Ronald, K. Mallams Alan, M. Kelly Joseph, W. Remiszewski Stacy
Принадлежит: Schering Corporation
Реферат: (Formül(I), (Formül(II), Formül(III), Formül(IV), Formül(V), Formül(VI)); Formüller, (I), (II), (III), (IV), (V) ve (VI) gibi, yeni bilesikler açiklanmaktadir. Ayni zamanda açiklanan, hücrelerin anormal büyümesinin önlenmesine mahsus, farnesil protein transferazi'nin önlenmesine mahsus ve yeni bilesiklerin kullanilmasi ile kanser hastaliklarinin tedavi edilmesine mahsus yöntemlerdir. (Formula (I), (Formula (II), Formula (III), Formula (IV), Formula (V), Formula (VI)); Formulas, (I), (II), (III), (IV) New compounds are disclosed, such as (V) and (VI). Also disclosed are methods for the treatment of cancer diseases for the prevention of abnormal growth of cells, for the prevention of farnesyl protein transferase and by the use of new compounds.
Benzo(5,6)cyclohepta(1,2-b)pyridine derivatives for the inhibition of farnesyl protein transferase
Номер патента: CA2294347A1. Автор: F. George Njoroge,Joseph M. Kelly,Ronald J. Doll,Alan K. Mallams,Arthur G. Taveras,Stacy W. Remiszewski. Владелец: Stacy W. Remiszewski. Дата публикации: 1998-12-23.