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immunotherapies against various tumors including gastrointestinal and gastric cancer

Реферат: imunoterapias contra vários tumores, incluindo câncer gastrointestinal e gástrico. a presente invenção refere-se a peptídeos, ácidos nucleicos e células para utilização em métodos imunoterapêuticos. em particular, a presente invenção refere-se á imunoterapia do câncer. a presente invenção refere-se ainda a epitops peptídicos de célula t citotóxica (ctl) associados a tumores, sozinhos ou em combinação com outros peptídeos associados a tumores, que sirvam de ingredientes farmacêuticos ativos em composições de vacinas estimuladoras de respostas imunes antitumorais, a presente invenção refere-se a 95 novas sequências peptídicas e suas variações derivadas de moléculas hla classe i de células tumorais humanas utilizáveis em composições de vacinas para provocar respostas imunes antitumorais. immunotherapies against various tumors, including gastrointestinal and gastric cancer. The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to cancer immunotherapy. The present invention further relates to tumor-associated cytotoxic t-cell (ctl) peptide epitops alone or in combination with other tumor-associated peptides serving as active pharmaceutical ingredients in antitumor immune response stimulating vaccine compositions. The invention relates to 95 novel peptide sequences and variations thereof derived from human tumor cell class Ila molecules usable in vaccine compositions to elicit anti-tumor immune responses.

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