Amino acid ester containing azole antifungals
Номер патента: AU725302C
Опубликовано: 23-08-2001
Автор(ы): Jan Heeres, Lieven Meerpoel, Robert Jozef Maria Hendrickx
Принадлежит: Janssen Pharmaceutica NV
Опубликовано: 23-08-2001
Автор(ы): Jan Heeres, Lieven Meerpoel, Robert Jozef Maria Hendrickx
Принадлежит: Janssen Pharmaceutica NV
Реферат: The present invention concerns novel compounds of formulathe N-oxide forms, the pharmaceutically acceptable addition salts thereof and stereochemically isomeric forms thereof, wherein -A-B- forms a bivalent radical of formula -N=CH- (a), -CH=N- (b), -CH=CH- (c), L represents the acyl moiety of an amino acid; D is an azole containing 1,3- or 1,4-dioxolane derivative as broad-spectrum antifungals; their preparation, compositions containing them and their use as a medicine.
Amino acid esters, methods of their synthesis, intermediate compounds, pharmaceutical composition and method of its preparing
Номер патента: RU2197489C2. Автор: Ян Херес,Ливен Мерпул,Роберт Йозеф Мария Хендрикс. Владелец: Жансен Фармасетика Н.В.. Дата публикации: 2003-01-27.