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治疗与神经损伤相关的精神障碍和疼痛的药物组合物和用途

Номер патента: CN111840300A
Опубликовано: 30-10-2020
Автор(ы): 侯舒容, 冯鹤敏, 张绪, 张鸽, 徐声辉, 贺菊方
Принадлежит: City University of Hong Kong CityU
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Derivatives of pyrimidine, pharmaceutical composition, inhibition method and using

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Compositions for treating abuse with substances causing painful addiction, and improvement of behaviour associated with abuse

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Bis[thio-hydrazide amide] derivatives, pharmaceutical compositions comprising them and uses thereof for the manufacture of medicaments to enhance the anti-cancer activity of paclitaxel or of a paclitaxel analog

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Topical compositions for treating and preventing hair loss and hair graying

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Method for treating melanoma

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Oxazole and thiazole compounds as β-catenin modulators and uses thereof

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Benzenesulfonamide composition for treating melanoma

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Methods for the treatment of post-traumatic stress disorder and traumatic brain injury with cannabinoids

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Methods for the treatment of post-traumatic stress disorder and traumatic brain injury with cannabinoids

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Treatment for neurological and mental disorders

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Use of eltoprazine for improving symptoms of cognitive impairment associated with non-adhd neurological and mental disorders

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Amino acid compositions and methods for use in the treatment of post-acute sequelae of covid-19

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Amino acid compositions and methods for the treatment of post-acute sequelae of COVID-19

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Delivery methods for treating brain and central nervous system diseases

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New isoindoline derivative, pharmaceutical composition including thereof and use thereof

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Antiproliferation compounds and uses thereof

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Compositions and methods for the treatment of prader-willi syndrome

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Pharmaceutical composition having an analgaesic and an antihistamine for treating respiratory diseases

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Pharmaceutical composition of proton pump inhibitor and prebiotic for treating gastric and duodenal ulcers

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New pharmaceutical compositions for inhalation

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Solid pharmaceutical composition for buccal administration of agomelatine

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Rorgamma modulators and uses thereof

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Bicyclic heteroaryl compounds as ?-secretase modulators, their manufacture, pharmaceutical compositions comprising them and their use for treating diseases associated with deposition of ?-amyloid in the brain

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Rorgamma modulators and uses thereof

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CONNECTIONS cinnamic acid derivatives, intermediates for their preparation and pharmaceutical compositions thereof, methods for inhibiting histone deacetylase, method of treating diabetes, METHOD FOR THE TREATMENT OF TUMORS or diseases associated with the proliferation of cells, a method of enhancing neurite outgrowth and methods for treating neurodegenerative diseases and spinal muscular atrophy

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Hydrazide compounds as thyroid hormone receptor modulators and uses thereof

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Carbohydrate derivatives, pharmaceutical composition based on thereof

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compound, pharmaceutical composition, processes for preparing a compound and a pharmaceutical composition, use of a compound, and method for treating or reducing the risk of an inflammatory disease or condition

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New aminoacid compounds for treating tumours and autoimmune diseases

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Compounds for treating spinocerebellar ataxia type 3

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Antisense molecules and their uses for the treatment of coronavirus infection, in particular the treatment of covid-19 related to sars-cov-2 infection

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4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof

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Arylamines useful for the treatment of conditions associated with gsk-3, process for producing them, pharmaceutical compositions containing them and use thereof

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N-substituted 2-cyanopyrrolidines, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for treating conditions mediated by dpp-iv inhibition

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Bicycloheteroaryl compounds as P2X7 modulators and uses thereof

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Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof

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Bicycloheteroaryl compounds as p2x7 modulators and uses thereof

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Novel chemotypes for treating parasitic diseases and methods of use

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Substituted pyrazole-pyrimidines, variants thereof, and uses therefore

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Substituted pyrazole-pyrimidines, variants thereof, and uses therefore

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Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same

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Novel chemotypes for treating parasitic diseases and methods of use

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Myc modulators and uses thereof

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Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same

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Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same

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Thiohydantoins, process for their preparation, pharmaceutical compositions containing them and use thereof for preparation of pharmaceutical compositions

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Hydroxypyridone derivatives, pharmaceutical compositions thereof, and their therapeutic use for treating proliferative diseases

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Heterocyclic compounds, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for the treatment of ccr2b mediated conditions

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Hydroxypyridone derivatives, pharmaceutical compositions thereof, and their therapeutic use for treating proliferative diseases

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Cyclic aminooxy compounds inhibiting ornithin decarboxylase, process of their preparation, pharmaceutical compositions containing thereof and their use for treating animals or human beings

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Novel heterocyclic compounds, process of their preparation, pharmaceutical compositions containing thereof and their use for treating diabetes mellitus and related diseases

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Substituted imidazoles, their preparation and use

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COMPOUNDS, PROCESS FOR OBTAINING THE COMPOUNDS, PHARMACEUTICAL COMPOSITION, USE OF THE COMPOUNDS AND METHOD FOR TREATING PSYCHIATRIC DISORDERS AND/OR SLEEP DISORDERS

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PYRIMIDO-ISOQUINOLIN-QUINONE DERIVATIVE COMPOUNDS, AND PHARMACEUTICALLY ACCEPTABLE SALTS, ISOMERS AND TAUTOMERS THEREOF; PHARMACEUTICAL COMPOSITION; PREPARATION METHOD; AND USE THEREOF IN THE TREATMENT OF DISEASES CAUSED BY BACTERIA AND MULTIDRUG-RESISTANT BACTERIA

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Tropolone derivatives and pharmaceutical composition thereof for preventing and treating ischemic diseases

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Novel crystal forms of ondansetron, processes for their preparation, pharmaceutical compositions containing the novel forms and methods for treating nausea using them

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Compounds derived from spirocyclic heterocycles substituted by substituted quinazoline-linked ethers; pharmaceutical composition; pharmaceutical combination; and use in the treatment of lung and respiratory diseases, autoimmune disease, allergic diseases and cancer, among others.

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ANTIBIOTIC A 40926 N-acylaminoglucuronyl aglycons AND ANTIBIOTIC A40926 aglycone and pharmaceutically acceptable addition THEREOF, METHOD FOR PRODUCTION OF SUCH RELATIONS, pharmaceutical composition comprising RELATIONS AND USE OF SUCH COMPOUNDS FOR THE PREPARATION OF A DRUG

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Indole derivatives, pharmaceutical compositions comprising them and use thereof for the manufacture of a medicament for the treatment of diseases associated with over activity of osteoclasts

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N-substituted staurosporine derivatives and salts thereof, process for their preparation, pharmaceutical compositions containing them and use of the N-substituted staurosporine derivatives for the preparation of pharmaceutical preparations

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N-ETOXICARBONIL-3-MORFOLINO-SIDNON IMINA INCLUSION COMPLEX OR ITS SALT, PROCESS FOR ITS PREPARATION, PHARMACEUTICAL COMPOSITION, PROCESS FOR ITS PREPARATION, AND PROCESS FOR TREATING ANGINIC AND ISCHEMIC DISEASES IN HUMANS

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Non-hydrolyzable nucleoside di- or tri-phosphate derivatives and uses thereof

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Alpha crystalline form of strontium ranelate, a process for its preparation, and pharmaceutical compositions containing it

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COMPOUNDS 4-PIPERIDINYLMOLEVINS (OPTIONS), PHARMACEUTICAL COMPOSITION ON THEIR BASIS (OPTIONS) AND METHOD FOR TREATING DISEASES MEDIATED BY SOLVABLE EPOXYDROHYDROLOSE OF THE DISEASES MEDIATED BY SOLVABLE EPOXYDROHYDROLASO TREATMENT, TREATMENT OF THE DISTRIBUTION MEDIATED WITH SOLVABLE EPOXYDROHYDROLOSE OF THE DISEASE MEDIATED BY SOLVABLE EPOXYDROHYDROLA AROUND AND MEANS OF THE PROTECTION OF THE DISTRIBUTION, MEDIATED BY THE MEANS OF THE DISPOSAL OF THE DISEASE

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Non-nucleotide reverse transcriptase inhibitors, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for the prophylaxis or treatment of hiv-1 infections

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Non-hydrolyzable nucleoside di- or tri-phosphate derivatives and uses thereof

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Methods for treating sleep disorders in patients via renal neuromodulation

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4-aminotetrahydrobenzisoxazole or -isothiazole derivatives, pharmaceutical compositions containing them and their use for the preparation of pharmaceutical compositions

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Compounds derived from 4-fluoro-benzoic acid, hcv polymerase inhibitors, pharmaceutical composition, pharmaceutical kit and their use for the treatment of a viral infection by hepatitis c.

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Fused pyrazine compounds useful for the treatment of degenerative and inflmmatory diseases

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QUINOLINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD AND USE THEREOF

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Pyridine Derivative Inhibiting RAF Kinase and Vascular Endothelial Growth Factor Receptor, Method for Preparing Same, Pharmaceutical Composition Containing Same, and Use Thereof

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SUBSTITUTED PYRROLOPYRIMIDINE CDK INHIBITOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND USE THEREOF

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Novel benzoxazine benzimidazol derivatives, pharmaceutical composition comprising same, and use thereof

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4-OXO-6-AMINOMETHYL-QUINAZOLINE DERIVATIVES, PROCEDURES FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITION INCLUDING THEM AND USING THEM FOR THE TREATMENT OF TUMORS

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Multicyclic carbazole and carbazole-lactam compound, pharmaceutical composition containing thereof and use of the compound

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Aminoalcohol derivatives, pharmaceutical compositions containing them, and uses thereof

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COMPOUNDS DERIVED FROM BICYCLE HETEROCICLES; PHARMACEUTICAL COMPOSITION; PREPARATION PROCEDURE; AND USE TO TREAT BENIGN OR MALIGNUM TUMORS, DISEASES OF THE RESPIRATORY ROADS, GASTROINTESTINAL TRACT, BILIARY DUCTS, VESICULA

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Compounds derived from 2-amino-chromen-4-one; pharmaceutical composition comprising it; and use in the treatment of a disease that is alleviated by inhibition of DNA-dependent protein kinase (DNA-pk), such as cancer.

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Ppar active compounds, pharmaceutical compositions comprising them and uses thereof for preparing medicaments

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Compounds derived from imidazopyridinones, tlr7 agonist; preparation procedure; intermediate compounds; pharmaceutical composition comprising them; and use in viral, bacterial and fungal infections.

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Substituted imidazoles and thiazoles, pharmaceutical composition containing them and use thereof

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Indoles active as modulators of nicotinic acetylcholin receptor subtype alpha-7, pharmaceutical compositions comprising them and use thereof in the manufacture of medicaments for the treatment of psychotic disorders

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Phenyl-piperazine derivatives as serotonin reuptake inhibitors, pharmaceutical compositions containing them and use thereof

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Boron-containing compounds, pharmaceutical compositions comprising them and uses thereof in inhibiting arginase

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Monoester compound, pharmaceutical composition it containing, and use of this compound

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Sulfonyl-substituted bicyclic compounds, pharmaceutical compositions comprising them and uses thereof in the manufacture of medicaments

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? Dihydrobenzofuranyl-piperidinyl, aza-dihydrobenzofuranylpiperidinyl and diaza-dihydrobenzofuranyl-piperidinyl derivatives, pharmaceutical compositions containing them and uses thereof?

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2-Cyano-3-hydroxy-propenamide, a process for its preparation, pharmaceutical compositions containing it and uses thereof as medicaments

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Microbial compositions and methods of using for improving plant growth and treating plant diseases

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