Viral vectors for cancer therapy
Номер патента: EP4314028A1
Опубликовано: 07-02-2024
Автор(ы): Dana Michelle Previte, Mary Jane Duermeyer, Suma Krishnan, Trevor Parry
Принадлежит: Krystal Biotech Inc
Опубликовано: 07-02-2024
Автор(ы): Dana Michelle Previte, Mary Jane Duermeyer, Suma Krishnan, Trevor Parry
Принадлежит: Krystal Biotech Inc
Реферат: The present disclosure provides recombinant nucleic acids comprising one or more polynucleotides encoding an immunomodulatory polypeptide (e.g., a pro-inflammatory cytokine such as a human IL- 2 or IL- 12 polypeptide); viruses comprising the recombinant nucleic acids; compositions and formulations comprising the recombinant nucleic acids and/or viruses; methods of their use (e.g., for the treatment of cancer, such as lung cancer); and articles of manufacture or kits thereof.
Adenovirus/alfavirus hybrid vector for effective administration and expression of therapeutic genes in tumor cells
Номер патента: RU2394104C2. Автор: ВАЛЬТУЭНЬЯ Хесус ПРЬЕТО,Чэн ЦЯНЬ,Минь ГУАНЬ,ПИКАЗО Кристиан СМЕРДОУ. Владелец: Проекто Де Биомедисина Сима, С.Л.. Дата публикации: 2010-07-10.