Tissue-derived extracellular vesicles and their use as diagnostics
Номер патента: EP3602062A1
Опубликовано: 05-02-2020
Автор(ы): Jan Lötvall, Rossella Crescitelli, Su Chul Jang
Принадлежит: Individual
Опубликовано: 05-02-2020
Автор(ы): Jan Lötvall, Rossella Crescitelli, Su Chul Jang
Принадлежит: Individual
Реферат: The present disclosure relates to a method of isolating extracellular vesicles directly from human tissues. The invention further relates to a method of identifying disease and tissue specific membrane proteins on extracellular vesicles by membrane isolation and proteomic analysis. The invention further relates to methods of diagnosing diseases by capturing extracellular vesicles by the use of disease specific membrane proteins from body fluids, and detecting or analyzing molecular signatures (proteome, DNA, and RNA) on captured extracellular vesicles. Moreover, the present invention relates to kits, apparatus and software required for implementing aforementioned methods.
Tissue-derived extracellular vesicles and their use as diagnostics
Номер патента: WO2018171947A1. Автор: Su Chul Jang,Jan Lötvall,Rossella Crescitelli. Владелец: Loetvall Jan. Дата публикации: 2018-09-27.