Cathepsin propeptide and uses thereof
Номер патента: EP2001505A2
Опубликовано: 17-12-2008
Автор(ы): Christopher Scott, Jim Johnston, Mark Mccurley, Philip Snoddy, Richard Buick, Roberta Burden
Принадлежит: Fusion Antibodies Ltd
Опубликовано: 17-12-2008
Автор(ы): Christopher Scott, Jim Johnston, Mark Mccurley, Philip Snoddy, Richard Buick, Roberta Burden
Принадлежит: Fusion Antibodies Ltd
Реферат: A method of inhibiting activity of a cathepsin L-like protease in cells or tissue and the use of the method in the treatment of disease such as cancer and inflammatory diseases is described. The method comprises administration of a cathepsin propeptide or a nucleic acid encoding a cathepsin propeptide. In particular embodiments, the propeptide is a Cathepsin S propeptide. Further, the use of propeptides having an Fc portion is described.
Cathepsin propeptide and uses thereof
Номер патента: CA2643723A1. Автор: Christopher Scott,Roberta Burden,Jim Johnston,Richard Buick,Mark Mccurley,Philip Snoddy. Владелец: Individual. Дата публикации: 2007-09-07.