Recombinant classical swine fever virus e2 protein
Опубликовано: 23-08-2023
Автор(ы): Chao TONG, Huanhuan LIU, Jiaying Wang, Ning Chen
Принадлежит: Boehringer Ingelheim Vetmedica China Co Ltd
Реферат: The present invention relates to the field of animal health. Particularly, the present invention relates to a recombinant classical swine fever virus E2 protein comprising at least one mutation at the epitope specifically recognized by the 6B8 monoclonal antibody. Further, the present invention provides an immunogenic composition comprising the recombinant E2 protein of the present invention and the use of the immunogenic composition for preventing and/or treating diseases associated with CSFV in an animal. Moreover, the present invention provides a method and a kit for differentiating animals infected with CSFV from animals vaccinated with the immunogenic composition of the present invention. Furthermore, the present invention provides a method of producing the E2 protein.
Recombinant classical swine fever virus e2 protein with b/c domain swapping
Номер патента: EP4419137A2. Автор: Ning Chen,Chao TONG,Jiaying Wang,Huanhuan LIU. Владелец: Boehringer Ingelheim Vetmedica China Co Ltd. Дата публикации: 2024-08-28.