Quinoline derivatives and their use as antibiotics
Опубликовано: 02-01-2004
Автор(ы): Farouk Hussni Al-Hajjar
Принадлежит: Dar Al Dawa Development and Investment Co, Sc Dar Al Dawa Pharma Srl
Реферат: The compound having the general formula (I) <CHEM> wherein X is selected from the group consisting of oxygen, sulfur and nitrogen-containing groups selected from azine, oxime, hydrazone, aromatic hydrazone, aliphatic hydrazone, semicarbazone, guanidinyl group, or aliphatic or aromatic imines; Y is selected fron the group of halogens; R1 and R2 are independently selected from the group consisting of H, lower alkyl group (of C1 up to C6), lower hydroxyalkyl group (of C1 up to C6), lower O-alkyl group (of C1 up to C6), lower alkylcarbonyl group (of C1 up to C6), lower alkyloxycarbonyl group (of C1 up to C6), haloalkylcarbonyl group (of C1 up to C6), or arylsulfonyl group, and their pharmaceutically acceptable salts, are useful as active ingredients in pharmaceutical compositions. The invention relates to the use of the said compounds as a medicament, in particular as an antibiotic.
Halogenated quinoline derivatives as antimicrobial agents
Номер патента: WO2017053696A3. Автор: Robert William Huigens, III,Yasmeen Abouelhassan,Akash BASAK. Владелец: University of Florida Research Foundation, Incorporated. Дата публикации: 2017-07-20.