Secreted and cell surface genes expressed in benign and malignant colorectal tumors
Номер патента: EP1430071A4
Опубликовано: 02-11-2005
Автор(ы): Bert Vogelstein, Kenneth W Kinzler, Phillip Buckhaults
Принадлежит: JOHNS HOPKINS UNIVERSITY, School of Medicine of Johns Hopkins University
Опубликовано: 02-11-2005
Автор(ы): Bert Vogelstein, Kenneth W Kinzler, Phillip Buckhaults
Принадлежит: JOHNS HOPKINS UNIVERSITY, School of Medicine of Johns Hopkins University
Реферат: Particular genes are aberrantly and consistently expressed in both adenomas and carcinomas of the colon. Products of such genes provide stool and serum markers for colorectal neoplasia. One particular tumor marker, Renal Dipeptidase (RDP), is expressed at high levels in tumors and at greatly reduced levels in normal tissues. The elevated expression of RDP occurs early and remains elevated during the neoplastic process. RDP may therefore be especially useful as a diagnostic tool for the early detection of colorectal neoplasia, even of presymptomatic colorectal neoplasia.
Secreted and cell surface genes expressed in benign and malignant colorectal tumors
Номер патента: EP1430071B1. Автор: Bert Vogelstein,Kenneth W. Kinzler,Phillip Buckhaults. Владелец: School of Medicine of Johns Hopkins University. Дата публикации: 2011-04-06.