Inhibition of androgen receptor by extracts of medicinal herbs and compositions thereof
Номер патента: EP3720462A1
Опубликовано: 14-10-2020
Автор(ы): Wing Lam, Yung-Chi Cheng, Zaoli Jiang
Принадлежит: YALE UNIVERSITY
Опубликовано: 14-10-2020
Автор(ы): Wing Lam, Yung-Chi Cheng, Zaoli Jiang
Принадлежит: YALE UNIVERSITY
Реферат: In one embodiment, the present invention is directed to a composition comprising an aqueous or ethanolic extract of at least one herb selected from the group consisting of Aloe barbadensis (蔍薈:F3), Rheum palmatum L. (大黄:Β6) Stephania tetrandra (汉防己:C4), Phellodendron chinense Schneid. (黄柏:D8), Euphorbia humifusa (地錦草:S6), Eclipta prostrata (墨旱莲:I2), A. venetum L. (羅布麻:FI), Portulaca oleracea L. (马齿苋:F5) and Sanguisorba officinalis L. (地楡:E5}, Camellia sinensis var.assamica (Mast) Kitamura (普洱:PE) and Punica granatum. (石榴:PG); and mixtures thereof. The composition is administered to a patient, in an effective amount, in a method of treating, inhibiting, preventing, reducing the incidence of, ameliorating or resolving a disease state or condition caused in part or exacerbated by hyperactivity of the androgen receptor (AR), by inhibiting the androgen receptor protein. These compositions may also be used inhibit or stabilize hair loss or grow hair in a subject in need.
Inhibition of androgen receptor by extracts of medicinal herbs and compositions thereof
Номер патента: US20240226222A1. Автор: Wing Lam,Yung-Chi Cheng,Zaoli Jiamg. Владелец: YALE UNIVERSITY. Дата публикации: 2024-07-11.