Substituted pyrrole carboxamides, process for their preparation and their use as kinase inhibitors
Номер патента: EP4313971A1
Опубликовано: 07-02-2024
Автор(ы): Danilo Mirizzi, Helena Posteri, Ilaria Motto, Laura Buffa, Maria Menichincheri
Принадлежит: Nerviano Medical Sciences SRL
Опубликовано: 07-02-2024
Автор(ы): Danilo Mirizzi, Helena Posteri, Ilaria Motto, Laura Buffa, Maria Menichincheri
Принадлежит: Nerviano Medical Sciences SRL
Реферат: The application relates to substituted pyrrole carboxamide derivatives of formula (I) which modulate the activity of cycle 7-related protein kinase (Cdc7). The compounds of this invention are therefore useful in treating diseases related to dysregulated kinases activity, for example cancer, cell proliferative disorders, viral infections, immune disorders, neurodegenerative disorders, cardiovascular diseases and bone related diseases. The application also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and their medical uses.
Substituted pyrrole carboxamides, process for their preparation and their use as kinase inhibitors
Номер патента: US20240217969A1. Автор: Maria Menichincheri,Helena Posteri,Laura Buffa,Ilaria Motto,Danilo Mirizzi. Владелец: Nerviano Medical Sciences SRL. Дата публикации: 2024-07-04.