Enantioconvergent chemoenzymatic synthesis of (r)- gamma-amino-beta-hydroxybutyric acid ((r) -gabob)
Номер патента: EP1833977A1
Опубликовано: 19-09-2007
Автор(ы): Ahmed Kamal, Gollapalli Bhasker Ramesh Khanna, Rondla Ramu, Tadiparthi Krishnaji
Принадлежит: Council of Scientific and Industrial Research CSIR
Опубликовано: 19-09-2007
Автор(ы): Ahmed Kamal, Gollapalli Bhasker Ramesh Khanna, Rondla Ramu, Tadiparthi Krishnaji
Принадлежит: Council of Scientific and Industrial Research CSIR
Реферат: The present invention particularly relates to a chemoenzymatic process for the stereoselective preparation of both enantiomers of 3-hydroxy-4-trityloxy butanenitrile key intermediates for the preparation of (R)-GABOB by lipase mediated kinetic resolution of its racemates and their effective application in the enantioconvergent synthesis of (R)-GABOB.
Enantioconvergent chemoenzymatic synthesis of (R)-gamma-amino-beta-hydroxybutyric acid ((R)-GABOB)
Номер патента: US20060141606A1. Автор: Ahmed Kamal,Ramu Rondla,Gollapalli Khanna,Krishnaji Tadiparthi. Владелец: Council of Scientific and Industrial Research CSIR. Дата публикации: 2006-06-29.