Compositions and methods related to engineered fc-antigen binding domain constructs targeted to pd-l1
Номер патента: EP3820998A2
Опубликовано: 19-05-2021
Автор(ы): Anthony Manning, Daniel ORTIZ, Inc. Momenta Pharmaceuticals, Jonathan C. Lansing, Laura RUTITZKY
Принадлежит: Momenta Pharmaceuticals Inc
Опубликовано: 19-05-2021
Автор(ы): Anthony Manning, Daniel ORTIZ, Inc. Momenta Pharmaceuticals, Jonathan C. Lansing, Laura RUTITZKY
Принадлежит: Momenta Pharmaceuticals Inc
Реферат: Fc-antigen binding constructs having a PD-L1 binding domain and two or more Fc domains are described as are methods for using such constructs. Also described are polypeptides making up such constructs. Fc domain monomers that are included in the constructs can include amino acid substitutions that promote homodimerization or heterodimerization.
Compositions and methods related to engineered fc-antigen binding domain constructs targeted to pd-l1
Номер патента: WO2020014419A8. Автор: Jonathan C. Lansing,Daniel ORTIZ,Laura RUTITZKY,Anthony Manning. Владелец: MOMENTA PHARMACEUTICALS, INC.. Дата публикации: 2021-12-02.