Methods and compositions related to platelet releasate and platelet-rich fibrin
Номер патента: EP3920944A1
Опубликовано: 15-12-2021
Автор(ы): Anand Srinivasan
Принадлежит: Biobridge Global
Опубликовано: 15-12-2021
Автор(ы): Anand Srinivasan
Принадлежит: Biobridge Global
Реферат: The present disclosure provides compositions and methods comprising human platelet releasate (hPR), a xeno-free media supplement. The disclosure also relates to a cGMP process for the rapid, efficient and large-scale manufacturing of hPR that may be performed in less than 4 hours. The platelet releasate of the current disclosure prevents gelation of growth media alleviating the need for heparin or other anticoagulants. Mesenchymal stem cells expanded in the presence of platelet releasate have demonstrated superior expansion rates and potency compared to commercial supplements including platelet lysates. The releasate has therapeutic and medical applications. The disclosure also relates to compositions and methods related to platelet-rich fibrin.
Methods and compositions related to platelet releasate and platelet-rich fibrin
Номер патента: US20210361718A1. Автор: Anand Srinivasan. Владелец: Biobridge Global. Дата публикации: 2021-11-25.