New drug screening assay using regulatory macrophages
Номер патента: EP3721226A1
Опубликовано: 14-10-2020
Автор(ы): Edward Geissler, James Hutchinson, Madrona Paloma RIQUELME
Принадлежит: UNIVERSITAET REGENSBURG
Опубликовано: 14-10-2020
Автор(ы): Edward Geissler, James Hutchinson, Madrona Paloma RIQUELME
Принадлежит: UNIVERSITAET REGENSBURG
Реферат: The present invention relates to a method for identifying compounds that are able to modulate the development of certain regulatory T cells which are induced by regulatory macrophages. Since induced regulatory T cells (iTregs) play a crucial role in diseases and pathological conditions, the method is highly suitable for identifying potentially active therapeutics. The method is particularly suitable for the screening of large libraries of candidate drug substances, such as small molecule or antibody libraries.
New drug screening assay using regulatory macrophages
Номер патента: WO2019110370A1. Автор: James Hutchinson,Edward Geissler,Madrona Paloma RIQUELME. Владелец: Universitat Regensburg. Дата публикации: 2019-06-13.