Pparϒ agonist for the treatment of huntington's disease
Опубликовано: 27-08-2019
Автор(ы): Barbara FINCK, Lawrence Steinman
Принадлежит: Coherus Biosciences Inc
Реферат: INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 26 July 2018 (26.07.2018) WIP0 I PCT 0111111010 0111 °nolo mini on °mono oimIE (10) International Publication Number WO 2018/136635 Al (51) International Patent Classification: A61K 31/47 (2006.01) A61P 25/28 (2006.01) A61K 31/4704 (2006.01) (21) International Application Number: PCT/US2018/014240 (22) International Filing Date: 18 January 2018 (18.01.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/447,741 18 January 2017 (18.01.2017) US (71) Applicant: COHERUS BIOSCIENCES, INC. [US/US]; 333 Twin Dolphin Drive, Suite 600, Redwood City, CA 94065 (US). (72) Inventors: FINCK, Barbara; C/o Coherus Biosciences, Inc., 333 Twin Dolphin Drive, Suite 600, Redmond City, CA 94065 (US). STEINMAN, Lawrence; C/o Coherus Biosciences, Inc., 333 Twin Dolphin Drive, Suite 600, Red- wood City, CA 94065 (US). (74) Agent: POLYAKOV, Mark, V. et al.; Wood, Phillips, Katz, Clark & Mortimer, 500 West Madison Street, Suite 1130, Chicago, IL 60661 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). = (54) Title: PPARY AGONIST FOR THE TREATMENT OF HUNTINGTON'S DISEASE (57) : Methods of treatment of Huntington's disease or FIG. I its symptoms, with PPARY agonists, and in particular, the com- pound of formula (I) known as INT131: W O 20 18/ 136635 Al Placebo 0.1 mg CI 1 mg 4 mg CI (I) [Continued on next page] WO 2018/136635 Al MIDEDIMOHNOBEIEDEMIIMEHIMMERVON Published: — with international search report (Art. 21(3))
PPARy AGONIST FOR TREATMENT OF HUNTINGTON'S DISEASE
Номер патента: US20190350918A1. Автор: Lawrence Steinman,Barbara FINCK. Владелец: Coherus Biosciences Inc. Дата публикации: 2019-11-21.