Gene editing using homology-independent universal genome engineering technology
Номер патента: EP3752179A1
Опубликовано: 23-12-2020
Автор(ы): Scott SODERLING, Yudong Gao
Принадлежит: Duke University
Опубликовано: 23-12-2020
Автор(ы): Scott SODERLING, Yudong Gao
Принадлежит: Duke University
Реферат: Disclosed herein are the genetic constructs for a Homology-Independent Universal Genome Editing (HiUGE) system and methods of using said HiUGE system for genome editing. The invention relates to compositions comprising gRNA polynucleotides, insert polynucleotides, and a CRISPR-based nuclease or polynucleotide encoding a CRISPR-based nuclease.
GENE EDITING USING HOMOLOGY-INDEPENDENT UNIVERSAL GENOME ENGINEERING TECHNOLOGY
Номер патента: US20210047643A1. Автор: Gao Yudong,Soderling Scott. Владелец: . Дата публикации: 2021-02-18.