Peptide beta-turn mimetic compounds and processes for making them
Номер патента: EP1240169A1
Опубликовано: 18-09-2002
Автор(ы): Adam Golebiowski, Sean Rees Klopfenstein
Принадлежит: Procter and Gamble Co
Опубликовано: 18-09-2002
Автор(ы): Adam Golebiowski, Sean Rees Klopfenstein
Принадлежит: Procter and Gamble Co
Реферат: The subject invention involves compounds having structure (I), wherein: (a) R1 is hydrogen or alkyl; and R2 is selected from hydrogen, alkyl, aryl, heterocyclyl, carboxy and its esters and amides; or R1 and R2 are attached and are together alkylene or heteroalkylene; (b) R4 is selected from aryl, heteroaryl, and α,β-unsaturated conjugated aryl or heteroaryl; and (c) R5 is selected from hydrogen, alkyl, aryl, and heterocyclyl; and an optical isomer, diesteriomer, or enantiomer thereof; a salt, hydrate, ester, amide or imide thereof. The subject invention also includes libraries of such compounds, and processes for making the subject compounds and libraries.
Peptide beta-turn mimetic compounds and processes for making them
Номер патента: PL355971A1. Автор: Adam Golebiowski,Sean Rees Klopfenstein. Владелец: The Procter & Gamble Company. Дата публикации: 2004-05-31.