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2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer

Номер патента: US20240294505A1
Опубликовано: 05-09-2024
Автор(ы): Benjamin Bader, Christina KOBER, Detlef STÖCKIGT, Horst Irlbacher, Ilona GUTCHER, Lars Rose, Ludwig Zorn, Michael Platten, Norbert Schmees, Rafael CARRETERO, Ulrike Rohn
Принадлежит: Bayer AG, Bayer Pharma AG, Deutsches Krebsforschungszentrum DKFZ
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2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer

Номер патента: US11795164B2. Автор: Norbert Schmees,Benjamin Bader,Lars Rose,Detlef STÖCKIGT,Horst Irlbacher,Rafael CARRETERO,Ilona GUTCHER,Christina KOBER,Michael Platten. Владелец: Deutsches Krebsforschungszentrum DKFZ. Дата публикации: 2023-10-24.

2-Heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer.

Номер патента: BR112019016497A2. Автор: Norbert Schmees,Benjamin Bader,Ludwig Zorn,Lars Rose,Detlef STÖCKIGT,Horst Irlbacher,Rafael CARRETERO,Ulrike Rohn,Christina KOBER,Michael Platten,Llona Gutcher. Владелец: Bayer AG. Дата публикации: 2022-05-10.

2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer

Номер патента: ZA201905902B. Автор: Norbert Schmees,Benjamin Bader,Ludwig Zorn,Lars Rose,Detlef STÖCKIGT,Horst Irlbacher,Rafael CARRETERO,Ilona GUTCHER,Ulrike Rohn,Christina KOBER,Michael Platten. Владелец: Bayer AG. Дата публикации: 2021-05-26.

2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer

Номер патента: CA3052718A1. Автор: Norbert Schmees,Benjamin Bader,Ludwig Zorn,Lars Rose,Detlef STÖCKIGT,Horst Irlbacher,Rafael CARRETERO,Ilona GUTCHER,Ulrike Rohn,Christina KOBER,Michael Platten. Владелец: Bayer AG. Дата публикации: 2018-08-16.

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Process for the continuous finishing treatment of textile web materials

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Method and apparatus for the high-frequency treatment of moist material

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Method and apparatus for the corona discharge treatment of webs, and webs treated therewith

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Method and device for the wet-mechanical treatment of a mixture of materials, in particular of all kinds of waste

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Machine for the continuous wet treatment of textile thread formations, the process for operating the machine, as well as a non-touching catch-thread device

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Electrode Unit for the Corona Discharge Treatment of Synthetic Material Webs

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Method and an apparatus for the continuous pre-treatment of a cloth

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Process for the thermomechanical surface treatment of flat webs of material, particularly those made of paper and carton, by using adhesive agents

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Apparatus for the continuous heat treatment of granular material by means of a gas

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Reactor for the continuous thermal treatment of solids, particularly carbonaceous absorbents, and process of operating the same

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Process for the selective reclamation treatment of used foundry sand

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Apparatus for the continuous liquid treatment of running lengths of materials

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Reactors and apparatus for the physico-chemical treatments of substances in the solid, liquid or gaseous state

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Method and apparatus for the corona discharge treatment of webs, and webs treated therewith

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Plant and method for the detection and treatment of defects on surfaces

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Method and spraying apparatus for the thermal surface treatment of a metal product

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System and a method for the steam pre-treatment of chips in association with the production of chemical cellulose pulp

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Process for the wet-chemical treatment of disk-shape workpieces

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Improvements in reactors and apparatus for the physico-chemical treatments of substances in the solid, liquid or gaseous state

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Methods and compositions for the diagnosis and treatment of cellular proliferation disorders using 86604

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Methods and compositions for the diagnosis and treatment of iga nephropathy

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Methods and compositions for the diagnosis and treatment of cellular proliferation disorders using 86604

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Methods and compositions for the diagnosis and treatment of cellular proliferation disorders using 86604

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Process for the surface modification treatment of polymer and products produced therefrom

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Egfr/nedd9/tgf-beta interactome and methods of use thereof for the identification of agents having efficacy in the treatment of hyperproliferative disorders

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Treatment of cancers with micro-RNA inhibitors

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Device and method for large-scale flow solidification treatment of dredged sediment in pipeline without yard

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Environmental-friendly Process for the Treatment of Wastewater

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Treatment of cancers with micro-rna inhibitors

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Promedicines of modified 2'- and 3'-nucleosides for treatment of flaviviridae infections

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The plasma assisted catalytic treatment of gases

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Use of in1-ghrelin for the diagnosis of prostate cancer

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Measuring electric activity of cells for the evaluation of metastatic potential of cancer cells

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COMPOSITION CONTAINING ARAZYME FOR THE PREVENTION AND TREATMENT OF CANDER

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METHODS FOR IDENTIFYING AND COMPOUNDS USEFUL FOR THE DIAGNOSIS AND TREATMENT OF DISEASES INVOLVING INFLAMMATION

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USE OF ANTI-90K MONOCLONAL ANTIBODIES FOR THE PREVENTION AND TREATMENT OF TUMORS AND METASTASES THEREOF

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SUBSTITUTED BENZFUROCHROMENES AND RELATED COMPOUNDS FOR THE PREVENTION AND TREATMENT OF BONE RELATED DISORDERS

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COMPOSITION FOR THE PREVENTION AND TREATMENT OF ALOPECIA, OR FOR HAIR GROWTH

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Boron-substituted indazoles for the prevention and treatment of multiple sclerosis (ms) and other demyelinating, inflammatory and neurodegenerative diseases

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Estrogen receptor beta ligands for the prevention and treatment of multiple sclerosis (ms) and other demyelinating, inflammatory and neurodegenerative diseases

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Compounds, pharmaceutical compositions and a method for the prophylaxis and treatment of the adhesion process

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CANULA USED FOR THE PUNCH-FREE TREATMENT OF PURULENT SINUSITIS

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Agents for the prevention and treatment of parkinson's disease

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Intravenous pharmaceutical form of isolated and purified antibodies for the prevention and treatment of covid-19 and related diseases

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Agent for the prevention and treatment of liver diseases containing pyrazolopyrimidinone derivative

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Intravenous pharmaceutical form of isolated and purified antibodies for the prevention and treatment of covid-19 and related diseases

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A STRAIN OF LACTOBACILLUS HELVETICUS BACTERIA POSSIBILITY TO REDUCE THE BLOOD CHOLESTEROL LEVEL AND USED TO PRODUCE PREPARATIONS AND FOOD FOR THE PREVENTION AND TREATMENT OF HYPERIPLES

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Medicinal natural product from alternanthera sessilis for the prevention and treatment of anemia and other hematologic disorders, and process for the preparation thereof

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Medicinal natural product from alternanthera sessilis for the prevention and treatment of anemia and other hematologic disorders, and process for the preparation thereof

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Process for isolating and producing antibodies for the prevention and treatment of covid-19 and related diseases from blood plasma containing said antibodies

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AUTOANTIBODIES IN THE DETECTION AND TREATMENT OF CANCER

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DIAGNOSIS AND TREATMENT OF CANCER USING ANTI-TM4SF20 ANTIBODY

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Novel composition and methods for the treatment of psoriasis

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MEDICAMENTS FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES

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Bombesin analogs for treatment of cancer

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Method and pharmaceutical composition for the treatment of severe blood loss and for the inhibition or treatment of the hemorrag shock

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Pai-2 conjugates for the treatment and imaging of cancer

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PAI-2 conjugates for the treatment and imaging of cancer

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