Carboxylic acid containing indanyl compounds for the treatment of neurodegenerative diseases.

Carboxylic acid containing indanyl compounds for the treatment of neurodegenerative diseases

Номер патента: EP4444697A1
Опубликовано: 16-10-2024
Автор(ы): Jean-Francois BRAZEAU, Jeffrey M. Schkeryantz, Karin Worm, Patrick W. Papa, Rulin Ma
Принадлежит: Celgene Corp

Реферат: Provided herein are compounds and compositions thereof for modulating S1P5. In some embodiments, the compounds and compositions are provided for treatment of neurological diseases. Formula (I).

Рисунок 1. Взаимосвязь патентов (ближайшие 20).

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Treatment of late-onset neurodegenerative diseases in heterozygous npc1 gene mutation carriers

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Compounds for use in the treatment of axonal damage

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Composition for use in a method for the prevention and treatment of cognitive decline and/or forms of dementia

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An application of taurine in the preparation of products for the prevention and treatment of androgenetic alopecia

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Composition for the prevention or treatment of bone diseases comprising colforsin daropate

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L-carnitine or derivatives thereof and antioxidants for the prevention and treatment of diseases elicited by oxidative stress to the nervous and cardiovascular system

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Topical oral and/or systemic oral formulations containing a mixture based on lactoferrin, more efficacious in iron uptake, for the prevention and treatment of several pathologies

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An agent for the prevention and treatment of the initial dental caries

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Pharmaceutical composition for the prevention or treatment of alopecia comprising eremochloa ophiuroides extract or fractions thereof as an active ingredient

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The use of viburnum opulus or its tissues or products thereof for the prevention or treatment of herpes virus infections

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Composition for the prevention and treatment of skin diseases

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Composition for the prevention and treatment of skin diseases

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Nutritional solid compositions with acaricide activity for apiculture and their use for the prophylaxis and treatment of varroa infestations

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Method for the prophylaxis and treatment of diarrhoea in dogs

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Oral compositions for the prevention and treatment of inflammatory disorders of the colon

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Probiotics for the prevention or treatment of viral respiratory infections

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Lactiplantibacillus plantarum imc 510 for use in a method for the prevention and treatment of obesity

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Methods and compositions for the diagnosis and treatment of brown adipose cell disorders

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Enteral carbon monoxide for the prevention and treatment of ocular diseases

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Composition for the prevention and treatment of viral infections caused by retroviruses

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Method to enhance the immune system and used for the prevention and treatment of infectious diseases

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A method to enhance the immune system and used for the prevention and treatment of infectious diseases

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A composition containing arazyme for the prevention and treatment of cancer

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Composition for the prevention or treatment of respiratory diseases caused by fine dust comprising Agastache rugosa and licorice extract

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Composition and methods for the prevention and treatment of macular degeneration, diabetic retinopathy, and diabetic macular edema

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Use of the long pentraxin ptx3 for the prevention or treatment of viral diseases

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Use of the long pentraxin ptx3 for the prevention or treatment of viral diseases

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Use of the long pentraxin ptx3 for the prevention or treatment of viral diseases

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Method for the diagnosis and treatment of critically ill patients with endothelin, endothelin agonists and adrenomedullin antagonists

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Myogenic progenitor cells for use in an optimized method for the prevention and treatment of anal incontinence

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Barn dust extract for the prevention and treatment of diseases

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Methods for the detection and treatment of lung cancer

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Herbal compositions for the prevention or treatment of urinary incontinence and overactive bladder

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