PROCESS FOR PREPARING ALKOXYLATED DERIVATIVES OF .beta.-LACTAM ANTIBIOTICS
Номер патента: CA1059503A
Опубликовано: 31-07-1979
Автор(ы): Akiko Ando, Hideo Nakao, Hiroaki Yanagisawa, Masami Fukushima
Принадлежит: Sankyo Co Ltd
Опубликовано: 31-07-1979
Автор(ы): Akiko Ando, Hideo Nakao, Hiroaki Yanagisawa, Masami Fukushima
Принадлежит: Sankyo Co Ltd
Реферат: A B S T R A C T 7-Alkoxy-7-benzylideneaminocephem or 6-alkoxy-6-benzylideneaminopenam compounds, which are useful as intermediates in the preparation of therapeutically active cephalosporins or penicillins, are prepared by reacting the corresponding 7-benzylideneaminocephem or 6-benzylideneaminopenam with a halide cation-producing compound in the presence of an alcohol and of a base capable of forming a salt with a phenolic hydroxyl group or of converting a phenolic hydroxyl group to a phenolate ion.
Transdermal delivery systems of beta-lactam antibiotics
Номер патента: EP2656879A1. Автор: Chongxi Yu. Владелец: Individual. Дата публикации: 2013-10-30.