Water-insoluble preparations of peptide materials their production and their use
Реферат: 1413381 Water-insolubilized peptide preparations BAYER AG 29 March 1973 [30 March 1972] 15114/73 Heading C3H [Also in Division C2] A water-insoluble preparation comprises a peptide material, e.g. a protein, an enzyme, e.g. penicillin acylase enzyme inhibitor or amino acid bound to a cross-linked copolymer comprising the copolymerized residues: A: 0À1 to 50 wt. per cent of at least one α,#-olefinically unsaturated dicarboxylic acid anhydride having 4-9 carbon atoms; and B: 99À9 to 50 wt. per cent of at least one di- and/or polyacrylate or methacrylate of a diol and/or a polyol as hereinbefore defined; the said copolymer having a bulk volume of 1-4 to 30 ml./g. and a specific surface area of 1-500 m.<SP>2</SP>/g. and containing, after hydrolysis of the anhydride groups, 0À02 to 10 milliequivalents of acid per gram. The copolymerized residues A of the copolymer are preferably derived from at least one of maleic, itaconic and citraconic anhydrides, residues B are desired from diacrylates and dimethacrylates of diols having 2-4 carbon atoms, or of reaction products of 1 mol. of diols having 2-4 carbon atoms with 1-20 mols. of at least one alkylene oxide with 2-4 carbon atoms, and trimethylol propane trimethacrylate.
New water-insoluble preparations of peptide materials their production and their use
Номер патента: IE37474B1. Автор: . Владелец: Bayer AG. Дата публикации: 1977-08-03.