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Modified fibroblast growth factors-1 for the treatment of ocular disorders

Номер патента: EP3049100B1
Опубликовано: 20-11-2019
Автор(ы): David Eveleth, Kenneth A. Thomas
Принадлежит: TREFOIL THERAPEUTICS LLC
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Pharmaceutical composition for treatment of eye pain, containing PGE2 synthesis inhibitor

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Synergistic herbal compositions for the treatment of obesity and overweight

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Method for the diagnosis and treatment of essential primary hypertension

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The use of viburnum opulus or its tissues or products thereof for the prevention or treatment of herpes virus infections

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Use of carvedilol or derivatives thereof for the manufacture of a medicament for the prevention and treatment of viral infections

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Use of transdermal topical systems for the prevention and treatment of primary dysmenorrhea

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Compositions for the prevention and treatment of primary headache and migraine

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Remedy for the treatment of escherichiosis and citrobacteriosis of young cattle in early postnatal ontogenesis

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Cranberry Extract Useful in the Treatment and Prevention of Urinary Infections

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Method for the treatment of patients with carcinomas

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Human g protein-coupled receptor and modulators thereof for the treatment of cardiovascular disorders

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Modulation of sphingosine 1-phosphate metabolizing enzymes for the treatment of negative-strand RNA virus infections

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Compositions for the treatment of gluten intolerance and uses thereof

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Use of adipose tissue derived mesenchymal stem cells for the treatment of graft versus host disease

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Compositions and methods for the treatment of juvenile neuronal ceroid lipofuscinosis and related disorders

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Cd40l-specific tn3-derived scaffolds for the treatment and prevention of sjögren's syndrome

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Klotho protein and related compounds for the treatment and diagnosis of cancer

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Nicotinamide for use in the treatment and prevention of ocular neurodegenerative disorder (e.g. glaucoma)

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Viral strain for obtaining attenuated live culture vaccine for prevention and treatment of herpes zoster for adult population

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Human g protein-coupled receptor and modulators thereof for the treatment of obesity and conditions related thereto

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Materials and methods relating to the diagnosis and treatment of pre-eclampsia and diabetes

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Materials and methods relating to the diagnosis and treatment of pre-eclampsia and diabetes

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The use for the treatment and prevention of atherosclerosis of the protein-peptide complex (hereinafter BOD) obtained from embryonic nervous tissue or from the rapidly frozen embryonic brain of agricultural ungulates, affecting the return transport of cholesterol from the vascular wall and the monocyte activation profile in patients with severe atherosclerosis of the great vessels or with a predisposition to cardiovascular disease and a method for the prevention and treatment of patients with arteriosclerosis of the arterial vessels and with the disease evanesia caused by atherosclerosis of the main and peripheral vessels of the brain, heart, vessels of the lower extremities and aorta (two options)

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Nicotinamide for use in the treatment and prevention of ocular neurodegenerative disorder (e.g. glaucoma)

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Surface simulation synthetic peptides useful in the treatment of hyper-variable viral pathogens

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Use of the long pentraxin ptx3 for the treatment of diseases caused by an altered activation of the growth factor fgf-2

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2- ( (2, 3-dihydroxypropyl) aminomethyl) chromane derivatives for use as beta-3 adrenoreceptor agonists in the treatment of urological and inflammatory disorders

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Pyridazino- pyridinone compounds for the treatment of protein kinase mediated diseases.

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5 Amino-2-carbonylthiophene derivatives for use as p38 map kinase inhibitors in the treatment of inflammatory diseases

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Benzene disulfonamide for the treatment of cancer

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Benzene disulfonamide for the treatment of cancer

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Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases

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Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases

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3-(2-aminopyrimidin-4-yl)-5-(3-hydroxypropynyl)-1H-pyrrolo[2,3-C]pyridine derivatives as NIK inhibitors for the treatment of cancer

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Pyrimidine derivatives useful for the treatment of diseases mediated by crth2

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Aromatic imidazolidinone derivatives and their use in the treatment of diseases of bacterial nature

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Anti-inflammatory agent for prevention and treatment of periodontitis

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Couplable portable device for the thermal medical treatment of skin

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Wristband for the use in treatment of carpal tunnel syndrome

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Means for the detection and treatment of prostate cells

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Device for the non-invasive treatment of muscular and neuromuscular pathologies and support to aesthetic treatments

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Machine for the continuous wet treatment of textile thread formations, the process for operating the machine, as well as a non-touching catch-thread device

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Method and apparatus for the corona discharge treatment of webs, and webs treated therewith

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Biomarkers for the diagnosis and treatment of gastric cancer

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Method and spraying apparatus for the thermal surface treatment of a metal product

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Process for the wet-chemical treatment of disk-shape workpieces

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Process for the surface modification treatment of polymer and products produced therefrom

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Prediction and treatment of immunotherapeutic toxicity

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Prediction and treatment of immunotherapeutic toxicity

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Triazolopyrazine compounds useful for the treatment of degenerative & inflammatory diseases

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Bicyclic carbohydrates for the treatment of infections caused by the alphaherpesvirinae hsv-1 and hsv-2

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Bicyclic carbohydrates for the treatment of infections caused by the alphaherpesvirinae hsv-1 and hsv-2

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Bicyclic carbohydrates as antiviral bioactives for the treatment of infections caused by the alphaherpesvirinae HSV-1 and HSV-2

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Device and method for large-scale flow solidification treatment of dredged sediment in pipeline without yard

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Promedicines of modified 2'- and 3'-nucleosides for treatment of flaviviridae infections

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Boron-substituted indazoles for the prevention and treatment of multiple sclerosis (ms) and other demyelinating, inflammatory and neurodegenerative diseases

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Compounds, pharmaceutical compositions and a method for the prophylaxis and treatment of the adhesion process

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Agents for the prevention and treatment of parkinson's disease

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Agent for the prevention and treatment of liver diseases containing pyrazolopyrimidinone derivative

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Medicinal natural product from alternanthera sessilis for the prevention and treatment of anemia and other hematologic disorders, and process for the preparation thereof

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Novel composition and methods for the treatment of psoriasis

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AUTOANTIBODIES IN THE DETECTION AND TREATMENT OF CANCER

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Method and pharmaceutical composition for the treatment of severe blood loss and for the inhibition or treatment of the hemorrag shock

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2,4-di(phenylamino)pyrimidines, applied in treatment of neoplastic diseases, inflammatory disorders and immune system disorders

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Fibroblast growth factor 1 (FGF-1) used for skin caring

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