Process for preparing a neutralized oxidized cellulose product and its method of use
Номер патента: CA2033046A1
Опубликовано: 13-07-1991
Автор(ы): Cary Linsky, David Wiseman, Lola Kamp, Lowell Saferstein, Stephen Wolf
Принадлежит: Cary Linsky, David Wiseman, Johnson & Johnson Medical, Inc., Lola Kamp, Lowell Saferstein, Stephen Wolf
Опубликовано: 13-07-1991
Автор(ы): Cary Linsky, David Wiseman, Lola Kamp, Lowell Saferstein, Stephen Wolf
Принадлежит: Cary Linsky, David Wiseman, Johnson & Johnson Medical, Inc., Lola Kamp, Lowell Saferstein, Stephen Wolf
Реферат: Oxidized cellulose material is neutralized, by contacting an acidic oxidized cellulose material with a water and alcohol solution of a basic salt of a weak organic acid, e.g. sodium acetate, to elevate the pH of the cellulosic material to between 5 and 8. The resulting neutralized product is storage stable and has therapeutic applications, including hemostasis and adhesion prevention. Furthermore, the neutralized product may be impregnated with acid-sensitive hemostatic agents, such as thrombin, to enhance its hemostatic properties, or with acid-sensitive adhesion-preventive agents, such as t-PA, to enhance its adhesion-prevention properties.
Process for preparing a neutralized oxidized cellulose product and its method of use
Номер патента: CA2033046C. Автор: Lowell Saferstein,Stephen Wolf,Lola Kamp,Cary Linsky,David Wiseman. Владелец: Johnson and Johnson Medical Inc. Дата публикации: 1999-08-03.