Process for producing aziridine-2-carboxylic acid or its salts
Опубликовано: 07-02-1984
Автор(ы): Akihiro Yamaguchi, Chojiro Higuchi, Nobuyuki Kawashima, Ryuichi Mita, Shosuke Nagai, Takao Takano, Toshio Kato
Принадлежит: Mitsui Toatsu Chemicals Inc
Реферат: Title of the Invention CARBOXYLIC ACID OR ITS SALTS Abstract of the Disclosure A process for producing aziridine-2-carboxylic acid or its salts is provided which comprises treating an alpha-halogeno-beta-aminopropionitrile or its mineral acid salt with an alkali or alkaline earth metal hydroxide in water or in a water-containing organic solvent. In a preferred embodiment, aziridine-2-carboxylic acid or its salt is produced by treating the reaction mixture containing an alpha-halogeno-beta-aminopropionitrile obtained by reacting an alpha,beta-dihalogenopropionitrile or an alpha- halogenoacrylonitrile with ammonia, with an alkali or alkaline earth metal hydroxide in the presence of water without isolating the alpha-halogeno-beta-aminopropionitrile from the reaction mixture beforehand.
Immunestimulating n-substituted aziridine- 2-carboxylic acid derivatives
Номер патента: CA1142530A. Автор: Wolfgang Kampe,Herbert Berger,Elmar Bosies,Uwe Bicker,Alfred Grafe. Владелец: Boehringer Mannheim GmbH. Дата публикации: 1983-03-08.