Настройки

Укажите год
-

Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

Подробнее
-

Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

Подробнее

Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Укажите год
Укажите год
Применить Всего найдено 4341. Отображено 100.
26-01-2012 дата публикации

Inspection systems and methods for blow-molded containers

Номер: US20120018925A1
Автор: Georg V. Wolfe, William E. Schmidt
Принадлежит: AGR International Inc

Systems and methods for in-line inspection of plastic blow molded containers. The inspection system may comprise a plurality of emitter assemblies arranged in a vertical array. Each emitter assembly may cyclically emit light energy in at least two different narrow wavelength bands at a container as the container passes through an inspection area. The system may also comprise a plurality of broadband photodetectors arranged in a vertical array, each photodetector facing at least one of the emitter assemblies with the inspection area therebetween such that the photodetectors are capable of sensing light energy that passes through the container when it is in the inspection area. The system may also comprise a processor in communication with the photodetectors for determining a characteristic of the container based on signals from the photodetectors.

Подробнее
Номер записи: 1
08-03-2012 дата публикации

Blood Chamber for an Optical Blood Monitoring System

Номер: US20120059234A1
Автор: Louis L. Barrett, Perry N. Law
Принадлежит: Hema Metrics LLC

An extracorporeal blood chamber for an optical blood monitoring system includes an opaque chamber body in order to prevent inaccuracies when measuring oxygen saturation levels due to light ducting, which can occur at low oxygen saturation levels and low hematocrit levels. In one embodiment, the blood chamber need not include a moat as is present in conventional blood chambers.

Подробнее
Номер записи: 2
26-04-2012 дата публикации

Method and Device for Measuring the Thickness of a Fountain Solution Layer or Ink Emulsion Layer in Offset Printing

Номер: US20120097851A1
Автор: Klaus-P. Dotzel
Принадлежит: GVT GMBH

A method and a device for measuring the thickness of a fountain solution layer or ink emulsion layer on the surface of a cylinder bearing the print image of an offset printing machine is proposed, in which the absorption of reflected near infrared radiation is measured by the dampening water that is applied during print production. Interferences due to optical reflection are eliminated by means of a gloss trap. A position-controlled regulation of the dampening water allocation is reliably maintained by means of machine synchronization of the measuring unit and receiving unit.

Подробнее
Номер записи: 3
13-09-2012 дата публикации

Self-contained and portable optical spectrometer

Номер: US20120229809A1
Автор: Antoine Bourely, Jean-Louis Ferrandis, Jean-Marc Gialis, Jean-Michel Roger, Roger Pellenc, Véronique Bellon Maurel
Принадлежит: Pellenc SAS

The invention relates to a portable and self-contained optical spectrometer for analyzing a light spectrum backscattered by an illuminated sample, in order to deduce the content of at least one compound constituting the sample, said spectrometer being arranged about an optical axis and including: a target area centered on said optical axis; a plurality of optical sensors trained on the target area; an opaque measurement chamber including: an opening centered on said optical axis; at least one diffusing filter blocking said opening; and an inner bottom capable of housing the plurality of optical sensors and a main illumination device capable of illuminating the sample. The invention further relates to a method for using such a spectrometer.

Подробнее
Номер записи: 4
03-01-2013 дата публикации

Homogenizing Light Sources in Photoplethysmography

Номер: US20130006074A1
Автор: Jonas A. Pologe
Принадлежит: Kestrel Labs Inc

An embodiment of a light homogenizing apparatus having one or more emitters ( 110, 120 ) incident on a light mixing element. The emitters including at least one laser light source. The light mixing element comprising a diffuser ( 130 ) followed by an internally reflective light guide ( 160 ). This apparatus substantially homogenizes light from all emitters ( 110, 120 ) before light exits the internally reflective light guide ( 160 ) where it could then be incident on living tissue for use in photoplethysmographic measurement. Other embodiments are described and shown.

Подробнее
Номер записи: 5
14-02-2013 дата публикации

Blood analysis apparatus and blood analysis method

Номер: US20130038860A1
Автор: Akira Niwa, Eriko Matsui, Hirokazu Tatsuta, Megumu Saito, Suguru Dowaki, Takeshi Kunihiro, Tatsutoshi Nakahata
Принадлежит: KYOTO UNIVERSITY, Sony Corp

A blood analysis apparatus includes an analysis section. The analysis section is configured to compare a measurement spectrum obtained regarding red blood cells with a standard spectrum of heme, biliverdin, and bilirubin, and cause the measurement spectrum to belong to any one of the standard spectra.

Подробнее
Номер записи: 6
14-03-2013 дата публикации

Device and Method for Detecting and Monitoring Ingredients or Properties of a Measurement Medium, In Particular of Physiological Blood Values

Номер: US20130066172A1
Автор: Axel Kulcke
Принадлежит: SENSPEC GMBH

The invention relates to a device for detecting and monitoring ingredients or properties of a measurement medium, for example physiological blood values, wherein said device contains a light source ( 20 ) for generating broad-spectrum measurement light ( 2 ) and for acting on a measurement area ( 3 ), and means ( 9 ) for fanning out the analysis light ( 4 ) reflected by the measurement area ( 3 ). The device also has a sensor array ( 11 ) for picking up the fanned light. The sensor array ( 11 ), the light source ( 20 ) and the means for dispersing the analysis light ( 4 ) are arranged as a compact unit in a housing.

Подробнее
Номер записи: 7
28-03-2013 дата публикации

Apparatus and Method for Detecting and Quantifying Analytes in Solution

Номер: US20130075614A1
Автор: Frank Thomas Hartley
Принадлежит: ROC8SCI Co

A method for identifying and quantifying one or more analytes included in a sample comprising a background solvent is disclosed. The present invention locates a sample fluid at a sample region by virtue of a sample holder that comprises work-hardened silver halide. The sample fluid at the sample region is then spectrally characterized via a mid-infrared spectrometer.

Подробнее
Номер записи: 8
06-01-2022 дата публикации

PROBE SUITABLE FOR MEASURING THE COMPOSITION OF AN OXIDISING GAS

Номер: US20220003686A1
Автор: DIGNETON Mathias, FLOT Patrice
Принадлежит: CMR GROUP

A probe including a spectrometer adapted to measure the composition of an oxidizing gas after analysis of at least one portion of a light beam having interacted with said gas. The spectrometer includes: a light source adapted to emit a light beam, an optical device comprising optical elements which are configured to guide, towards the gas to be analyzed, at least one portion of the light beam, and guide, towards a detector, a portion of the light beam having interacted with the gas. Further, the probe includes a cage adapted to be removably installed inside a channel through which the gas to be analyzed flows, the cage is configured to permit a flow of the gas through said cage, and at least one portion of the light beam propagates through the cage so as to be able to interact with the gas. 119.-. (canceled)20. A probe comprising a spectrometer adapted to measure the composition of an oxidizing gas after analysis of at least one portion of a light beam having interacted with said gas , said spectrometer comprising:a light source adapted to emit a light beam, guide, towards the gas to be analyzed, at least one portion of the light beam, and', 'guide, towards a detector, a portion of the light beam having interacted with the gas,, 'an optical device including optical elements configured towherein:the probe includes a cage adapted to be removably installed inside a channel wherein the gas to be analyzed flows,the cage is configured to permit a flow of the gas through said cage,at least one portion of the light beam propagates through the cage so as to be able to interact with the gas,the cage serves as a holder for an optical reflector adapted to reflect, towards the detector, the portion of the light beam propagating through said cage and having interacted with the gas, and,the cage is formed by an elongate tube the sidewall of which contains apertures distributed over the perimeter of said wall, said apertures are configured to allow the gas to pass radially through ...

Подробнее
Номер записи: 9
07-01-2021 дата публикации

EUROPIUM BASED METAL ORGANIC FRAMEWORK FOR PALLADIUM SENSING

Номер: US20210002304A1
Автор: Al-Ahmed Amir, HELAL Aasif, YAMANI Zain Hassan Abdallah
Принадлежит: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

A method of detecting Pd in an aqueous solution is described. The method involves mixing an Eu-based metal organic framework with the aqueous solution and measuring the amount of fluorescence quenching. The fluorescence quenching is specific to Pd and also allows a 44 ppb detection limit of Pd. The Eu-based metal organic framework may be treated with a metal chelator and reused for sensitive detection of Pd. 1: A method of detecting Pd in an aqueous solution , the method comprising:mixing an Eu-based metal organic framework (Eu-MOF) with the aqueous solution to form a solution mixture, wherein the Eu-MOF comprises:{'sup': 3+', '3+', '3+, 'claim-text': [{'sup': '3+', 'wherein each Eu ion cluster is coordinated with a total of 6 linkers, and'}, 'wherein each linker has a dicarboxylic acid and two alkene groups;, 'Eu ion clusters, each Eu ion cluster comprising two Eu ions,'}measuring a fluorescence emission intensity of the solution mixture while irradiating the solution mixture with a wavelength in a range of 320-350 nm; and{'sup': '2+', 'comparing the fluorescence emission intensity to a second fluorescence emission intensity of a substantially similar solution mixture that does not contain Pd.'}2: The method of claim 1 , wherein the alkene groups are part of allyloxy groups.3: The method of claim 2 , wherein the linker is 2 claim 2 ,5-bis(allyloxy)terephthalic acid.4: The method of claim 1 , wherein the linker is present in the Eu-MOF with a weight percent in a range of 55-75 wt % claim 1 , relative to a total weight of the Eu-MOF.5: The method of claim 1 , wherein each Eu ion cluster is coordinated in a 2D layered structure.6: The method of claim 5 , wherein the 2D layered structure has an interlayer spacing in a range of 3.2-3.8 Å.7: The method of claim 1 , wherein the Eu-MOF has an average pore size in a range of 3.5-4.5 Å.8: The method of claim 1 , wherein the Eu-MOF has a pore volume in a range of 0.10-0.20 cm/g.9: The method of claim 1 , wherein the Eu-MOF ...

Подробнее
Номер записи: 10
12-01-2017 дата публикации

APPARATUS FOR DETERMINING A MEASURED VALUE OF A MEASURAND IN PROCESS AUTOMATION TECHNOLOGY AND ITS METHOD OF USE

Номер: US20170010248A1
Автор: Krätschmer Thilo, Müller Frank, Steuerwald Ralf
Принадлежит:

The disclosure includes an apparatus for determining a measured value in a liquid medium, comprising at least a light transmitter, at least one light receiver assigned to the transmitter, a measuring chamber that can be filled with the medium, wherein an optical path runs through the measuring chamber from the transmitter to the receiver. The apparatus includes a dosing apparatus for dosing at least one reagent and/or the medium, and for inserting the dosed reagent and/or the medium into the measuring chamber. The dosing apparatus is designed as a tube, and the tube includes at least a first control point, wherein the volume in the tube from a starting point to a first control point defines the amount of reagent or medium to be inserted into the measuring chamber. The disclosure further includes the use of the apparatus and a method for dosing the reagent. 1. An apparatus for determining a measured value of a measurand in a liquid medium by means of an optical sensor comprising:at least one transmitter for transmitting transmitted light;at least one receiver associated with the transmitter for receiving received light;a measuring chamber, wherein an optical measuring path extends through the measuring chamber from the transmitter to the receiver;at least one dosing apparatus structured to generate a dosage of at least one reagent and/or the medium and for providing the dosage of the at least one reagent and/or the medium into the measuring chamber, wherein the dosing apparatus is a tube including a first control point, and wherein a volume of the tube from a starting point to the first control point defines the amount of a reagent or the medium to be provided into the measuring chamber; anda superordinate unit configured to generate an excitation signal to produce the transmitted light,wherein the transmitted light is converted into the received light by means of interaction along the measuring path in the measuring chamber with the at least one reagent and the ...

Подробнее
Номер записи: 11
14-01-2016 дата публикации

Method for Quantitatively Measuring the Concentration of a Compound of Unknown Concentration in Solution

Номер: US20160011099A1
Автор: Shih I-Tsung
Принадлежит:

The present invention relates to methods of spectrophotometric determination of the presence of particular substances in a complex mixture of compounds. This invention relates to methods for determining the concentration of various components of complex biological samples including the determination of the concentration of polyoxyethylene containing compounds including polysorbate in protein containing samples as well as determining the ratio of drug to antibody ratios in antibody-drug conjugate solutions 1. A method for determining the concentration of a second compound in a solution comprising buffer and a first compound and a second compound comprising:a. collecting a set of optical density versus wavelength spectra at two or more path lengths of the buffer of a solution containing first compound only to produce a first buffer background spectra;b. collecting a set of optical density versus wavelength spectra at two or more path lengths for the solution containing first compound only;c. correcting the solution containing first compound spectra with the first buffer background spectra to produce a first compound background corrected spectra;d. selecting two or more data points at a first wavelength from the first compound background corrected spectra and performing linear regression on the data points to produce a first slope;e. selecting two or more data points at a second wavelength from the first compound background corrected spectra and performing linear regression on the data point to produce a second slope;f. calculating the ratio of the slopes at the first and second wavelengths for the first compound;g. collecting a set of optical density versus wavelength spectra at two or more path lengths of a buffer of a solution containing a known concentration of the second compound only to produce a second buffer background spectra;h. collecting a set of optical density versus wavelength spectra at two or more path lengths of a solution containing a known ...

Подробнее
Номер записи: 12
11-01-2018 дата публикации

Maturity determination device and maturity determination method

Номер: US20180011008A1
Автор: Daiichiro Nakashima, Mitsuru Nakura, Rieko Ogawa, Takashi Nakano
Принадлежит: Sharp Corp

A maturity determination device includes an image capturing device to capture a image including a plurality of first and second pixels; and a signal processing circuit configured to find an area size ratio of an intensity distribution of light of a first wavelength band on the basis of a predetermined reference value based on pixel values obtained from the plurality of first and second pixels, and to generate maturity determination information in accordance with the area size ratio. The first pixel includes a first light transmission filter, and the second pixel includes a second light transmission filter. The intensity of the light of the first wavelength band reflected by the fruits and vegetables varies in accordance with the maturity level, and the intensity of the light of the second wavelength band reflected by the fruits and vegetables is substantially the same regardless of the maturity level.

Подробнее
Номер записи: 13
10-01-2019 дата публикации

SPECTROSCOPIC MEASURING DEVICE AND METHOD TO DETERMINE CONCENTRATIONS OF POLLUTANTS

Номер: US20190011354A1
Автор: HORBANSKI Martin, PLATT Ulrich, POEHLER Denis
Принадлежит:

The invention relates to a method for determining concentrations of absorbing gases by means of a spectroscopic measuring device, wherein wavelength-dependent measurement values for a light intensity are obtained and a wavelength-dependent measurement value function is represented based on these values. A wavelength-dependent theoretical function is defined, which includes as parameters a calibration parameter and the concentrations. The calibration parameter is defined as a function of a device parameter and a correction parameter that depends on the concentrations. A cycle comprising a sequence of steps is performed several times in a row, wherein in a first step a numerical value for the correction factor is calculated from stipulated assumed values of the concentrations, wherein in a second step the theoretical function is determined using the calculated numerical value, wherein in a third step values for the concentrations are obtained by a curve adjustment calculation between the theoretical function determined in the second step and the measurement value functions and are stipulated as new assumed values. The assumed values obtained in the third step of the last cycle are output as new measured values. 1. A method for determining at least one concentration of at least one absorbing gas in a gas mixture to be measured by means of a spectroscopic measuring device , which comprises a light source , a measuring cell comprising an optical resonator , a detector and a computer unit , wherein the gas mixture is arranged in the measuring cell and a light beam is sent to the measuring cell through an entrance of the measuring cell by means of the light source , wherein wavelength-dependent measurement values for a light intensity of light leaving from an exit of the measuring cell are obtained by means of the detector , wherein a wavelength-dependent shape of the light intensity is represented as a wavelength-dependent measurement value function and wherein a curve ...

Подробнее
Номер записи: 14
10-01-2019 дата публикации

Multi-rotor wing unmanned aerial vehicle platform based crop growth monitoring method and device

Номер: US20190011355A1
Автор: Fang Liu, Fangrong PANG, Jun Ni, Lili YAO, Weixing CAO, Xia YAO, Yan Zhu, Yongchao Tian
Принадлежит: NANJING AGRICULTURAL UNIVERSITY

A crop growth monitoring device based on a multi-rotor unmanned aerial vehicle platform includes a multi-rotor unmanned aerial vehicle, a payload and a ground receiver; the payload part includes a multispectral crop growth sensor module, a signal amplification module, a controller module, a wireless data transmission module, and a power module for power supply and a power supply control module, which are connected in sequence; further comprising a gimbal. The crop growth monitoring device based on the multi-rotor unmanned aerial vehicle platform overcomes the influence on measurement caused by the down-wash flow field of the unmanned aerial vehicle, and can transmit the measured data to the ground receiver in real time for online analysis and processing, realizing continuous, real-time, convenient and large-scope acquisition of crop growth information.

Подробнее
Номер записи: 15
14-01-2021 дата публикации

METHANE PEAK DETECTION

Номер: US20210010929A1
Автор: Herzl Davida, LaFranchi Brian, Langland Todd, Murphy Robert, Thurlow Meghan Elizabeth
Принадлежит:

A method for monitoring air quality is described. The method includes measuring ethane and methane using a mobile sensor platform to provide sensor data. The sensor data includes methane data and ethane data captured at a nonzero mobile sensor platform speed. Methane and ethane peak(s) are identified in the sensor data. Correlation(s) between the methane and ethane peak(s) and/or between the methane peak(s) and at least one amount of C are determined. A source for the methane is determined based on the correlation.

Подробнее
Номер записи: 16
03-02-2022 дата публикации

SYSTEM AND METHOD FOR MEASUREMENT SELECTION AND PROBE GUIDING IN A GINGIVITIS DETECTOR

Номер: US20220031169A1
Автор: Deane Steven Charles, SCHEFFERS Lucas Petrus Henricus, VERMEULEN Olaf Thomas Johan Antonie
Принадлежит:

A system () for detecting tissue inflammation, and gingivitis specifically, including a light emitter () configured to emit light at a tissue region () within a user's mouth; a light detector () configured to detect optical signals diffusely reflected through the tissue region over a period of time; a controller () configured to: determine a slope signal (Q) based on at least two signals (R(λ), R(λ)) from the optical signals, the at least two signals including at least one signal from a hemoglobin-dominated wavelength range; determine one or more characteristics of the slope signal; and select a best measurement signal based on the one or more characteristics of the slope signal. The system further includes a user interface () configured to provide information regarding a position of a probe for accurate detection of tissue inflammation based on the one or more characteristics of the slope signal. 1. A system for detecting tissue inflammation , comprising:a light emitter configured to emit light at a tissue region within a user's mouth;a light detector configured to detect optical signals diffusely reflected through the tissue region over a period of time; [{'sub': 1', '2, 'determine a difference signal (Q) based on the difference between at least two signals (R(λ), R(λ)) from the optical signals of different wavelengths, the at least two signals comprising at least one signal from a hemoglobin-dominated wavelength range and at least one from above the hemoglobin-dominated wavelength range;'}, 'determine one or more characteristics of the difference signal; and', 'select a best measurement signal based on the one or more characteristics of the difference signal; and, 'at least one controller characterized in that the controller is configured toa user interface configured to provide information regarding a position of a probe for accurate detection of tissue inflammation based on the one or more characteristics of the difference signal.2. The system of claim 1 , ...

Подробнее
Номер записи: 17
16-01-2020 дата публикации

Surgical visualization with proximity tracking features

Номер: US20200015899A1
Автор: Charles J. Scheib, Jeffrey S. Swayze
Принадлежит: Ethicon LLC

A surgical visualization system is disclosed. The surgical visualization system is configured to identify one or more structure(s) and/or determine one or more distances with respect to obscuring tissue and/or the identified structure(s). The surgical visualization system can facilitate avoidance of the identified structure(s) by a surgical device. The surgical visualization system can comprise a first emitter configured to emit a plurality of tissue-penetrating light waves and a second emitter configured to emit structured light onto the surface of tissue. The surgical visualization system can also include an image sensor configured to detect reflected visible light, tissue-penetrating light, and/or structured light. The surgical visualization system can convey information to one or more clinicians regarding the position of one or more hidden identified structures and/or provide one or more proximity indicators.

Подробнее
Номер записи: 18
21-01-2016 дата публикации

Multidimensional White Light Spectrometer

Номер: US20160018323A1
Автор: Martin Thomas Zanni
Принадлежит: WISCONSIN ALUMNI RESEARCH FOUNDATION

A multidimensional spectrometer provides broadband white light pump and probe pulses to allow acquisition of multidimensional spectral information over a wide range commensurate with solar-related chemical processes.

Подробнее
Номер записи: 19
25-01-2018 дата публикации

Lipid, protein, and metabolite markers for the diagnosis and treatment of prostate cancer

Номер: US20180024132A1
Автор: Albert Dobi, Leonardo Rodrigues, Michael Andrew KIEBISH, Niven Rajin Narain, Rangaprasad Sarangarajan, Shiv Srivastava, Viatcheslav R. Akmaev, Yezhou SUN
Принадлежит: Berg LLC, Henry M Jackson Foundation for Advancedment of Military Medicine Inc

Methods for diagnosing the presence of prostate cancer in a subject are provided, such methods including the detection of levels of a variety of biomarkers diagnostic of prostate cancer. The invention also provides methods of treating prostate cancer by administering a biomarker or an agent that modulates a biomarker of prostate cancer. Compositions in the form of kits and panels of reagents for detecting the biomarkers of the invention are also provided.

Подробнее
Номер записи: 20
23-01-2020 дата публикации

Methods for Determining Transition Metal Compound Concentrations in Multicomponent Liquid Systems

Номер: US20200023331A1
Автор: BUCK Richard M., YANG Qing
Принадлежит:

Methods for simultaneously determining the concentrations of transition metal compounds in solutions containing two or more transition metal compounds are described. Polymerization reactor systems providing real-time monitoring and control of the concentrations of the transition metal components of a multicomponent catalyst system are disclosed, as well as methods for operating such polymerization reactor systems. 111-. (canceled)12. A polymerization reactor system comprising:(A) a reactor configured to contact a catalyst system with an olefin monomer and an optional olefin comonomer under polymerization reaction conditions to produce an olefin polymer;(B) a catalyst preparation vessel configured to contact a first transition metal compound, a second transition metal compound, an activator, and an optional co-catalyst to form the catalyst system; and(C) an analytical system configured to determine a first concentration of the first transition metal compound and a second concentration of the second transition metal compound in a solution comprising the first transition metal compound and the second transition metal compound present within the polymerization reactor system; wherein:the polymerization reactor system comprises a slurry reactor, a gas-phase reactor, a solution reactor, or a combination thereof.13. The reactor system of claim 12 , wherein the analytical system comprises an ultraviolet-visible spectrometer.14. The reactor system of claim 13 , wherein the analytical system further comprises a filter assembly configured to filter a sample of the solution comprising the first transition metal compound and the second transition metal compound before analysis by the ultraviolet-visible spectrometer.15. The reactor system of claim 12 , wherein the reactor system further comprises (D) a controller configured to control a first flow rate of the first transition metal compound and/or a second flow rate of the second transition metal compound into the reactor based ...

Подробнее
Номер записи: 21
26-01-2017 дата публикации

Laser illuminated gas imaging

Номер: US20170024871A1
Автор: Derek Hutton, Matthew F. Schmidt, Tyler B. Evans
Принадлежит: Fluke Corp

Aspects of the invention generally relate to illumination gas imaging and detection. Camera systems can illuminate a target scene with light sources configured to emit absorbing and non-absorbing wavelengths with respect to a target gas. An image of the target scene illuminated with a non-absorbing wavelength can be compared to a non-illuminated image of the target scene in order to determine information about the background of the target scene. If sufficient light of the non-absorbing wavelength is scattered by the scene toward a detector, the target scene comprises an adequate background for performing a gas imaging process. A camera system can alert a user of portions of the target scene suitable or unsuitable for performing a gas imaging process. If necessary, the user can reposition the system until sufficient portions of the target scene are recognized as suitable for performing the gas imaging process.

Подробнее
Номер записи: 22
10-02-2022 дата публикации

Gas sensor with two switchable filters and method for operating such a gas sensor

Номер: US20220042903A1
Автор: Britta GREENBERG-FISMEN, Håkon Sagberg, Thor Christian HOBÆK
Принадлежит: Draeger Safety AG and Co KGaA

A gas sensor ( 2 ) distinguishes between a target gas and a contaminant and includes a light source ( 8 ), a measurement volume ( 4 ), a detector ( 22 ), and an adaptable filter system ( 20 ) with a first optical filter and a second optical filter. The filter system switches between a first composite state, with both filters in a reference state, a second composite state, with the first filter in a first reference state and the second filter in a second measurement state, a third composite state with the first filter in a first measurement state and the second filter in a second reference state, and a fourth composite state, with both filters in a measurement state. The gas sensor detects a target gas and makes a determination as to a presence of the contaminant by comparing the respective detector signals, generated during at least three of the composite states, with each other.

Подробнее
Номер записи: 23
24-01-2019 дата публикации

Methods for Determining Transition Metal Compound Concentrations in Multicomponent Liquid Systems

Номер: US20190025200A1
Автор: QING Yang, Richard M. Buck
Принадлежит: Chevron Phillips Chemical Co LP

Methods for determining the concentration of transition metal compounds in a solution containing more than one transition metal compound are described. Polymerization reactor systems providing real-time monitoring and control of the concentrations of the transition metal components of a multicomponent catalyst system are disclosed, as well as methods for operating such polymerization reactor systems and for improving methods of preparing the multicomponent catalyst system.

Подробнее
Номер записи: 24
24-01-2019 дата публикации

NDIR Glucose Detection in Liquids

Номер: US20190025207A1
Автор: Jacob Y. Wong, Thomas Campbell
Принадлежит: Airware Inc

For determining concentration of targeted molecules MG in a liquid sample admixed with interfering molecules MJ which overlap their absorption band, a special NDIR sampling and calibration technique is employed. Besides the signal source, a reference and one or more interference sources are added. The selection of the wavelength for the interference sources enables its measured transmittance value to be used for deciding the validity of the calibration curve for molecules MG in the liquid sample. This value can further be used to adjust the calibration curve via a parameter linking the transmittances measured at the signal and interference wavelength channels in order to assure its validity.

Подробнее
Номер записи: 25
17-02-2022 дата публикации

Bilirubin concentration measurement system

Номер: US20220047192A1
Автор: Azusa UOZUMI, Go INAMORI, Hiroki Ota, Shuichi Ito, Yutaka Isoda
Принадлежит: YOKOHAMA CITY UNIVERSITY, Yokohama National University NUC

A bilirubin concentration measurement system according to the present invention includes: a sensor device attachable to a subject; and a terminal device capable of wirelessly communicating with the sensor device. The sensor device includes: a light emitting element that emits blue light; a light emitting element that emits green light; a light detection element that detects reflected light that is the blue light having been incident on skin of the subject and been reflected, and detects reflected light that is the green light having been incident on the skin of the subject and been reflected; and a communication unit that wirelessly transmits information about intensities of the reflected light detected by the light detection element. The terminal device includes: a communication unit that receives the information about the intensities of the reflected light transmitted from the sensor device; and a computing unit that calculates a bilirubin concentration using the information about the intensities of the reflected light.

Подробнее
Номер записи: 26
01-02-2018 дата публикации

GAS ANALYSIS DEVICE, CONTROL SYSTEM AND CONTROL ASSISTANCE SYSTEM FOR COMBUSTION FACILITY, AND GAS ANALYSIS METHOD

Номер: US20180031233A1
Автор: Kawazoe Kohei, NISHIMIYA Tatsuyuki, OKA Hirotaka
Принадлежит:

A gas analysis device includes: a measurement part configured to measure an absorption amount of a laser light including an absorption wavelength corresponding to at least two electronic level transitions having the same component contained in the combustion gas, by emitting the laser light on a plurality of measurement paths disposed to pass through the combustion gas; a standard setting part configured to set a standard gas concentration distribution and a standard temperature distribution on the basis of a measurement result of the measurement part; and an analysis part configured to obtain the gas concentration distribution and the temperature distribution by solving a function including the gas concentration distribution and the temperature distribution as variables so as to minimize a difference between the absorption amount measured by the measurement part and a standard absorption amount obtained on the basis of the standard gas concentration distribution and the standard temperature distribution. 1. A gas analysis device for analyzing a concentration distribution of a combustion gas in a furnace and a temperature distribution inside the furnace , the gas analysis device comprising:a measurement part configured to measure an absorption amount of a laser light including an absorption wavelength corresponding to at least two electronic level transitions having the same component contained in the combustion gas, by emitting the laser light on a plurality of measurement paths disposed so as to pass through the combustion gas;a standard setting part configured to set a standard gas concentration distribution and a standard temperature distribution on the basis of a measurement result of the measurement part; andan analysis part configured to define the gas concentration distribution and the temperature distribution defined as a function including a common variable parameter and to obtain the gas concentration distribution and the temperature distribution by ...

Подробнее
Номер записи: 27
31-01-2019 дата публикации

Blood coagulation analyzer and blood coagulation analyzing method

Номер: US20190033289A1
Автор: Kazutoshi Tokunaga, Norimasa Yamamoto
Принадлежит: Sysmex Corp

A blood coagulation analyzer and analyzing method perform following: (a) preparing a measurement specimen by dispensing a blood specimen and a reagent into a reaction container; (b) emitting light of a plurality of wavelengths to the measurement specimen in the reaction container, the wavelengths comprising a first wavelength for use in a measurement by a blood coagulation time method, and at least one of a second wavelength for use in a measurement by a synthetic substrate method and a third wavelength for use in a measurement by an immunoturbidimetric method; (c) detecting light of a plurality of wavelengths corresponding to the light emitted in (b), from the measurement specimen, by a light receiving element, and acquiring data corresponding to each wavelength; and (d) conducting an analysis based on the data corresponding to one of the wavelengths among the acquired data, and acquiring a result of the analysis.

Подробнее
Номер записи: 28
04-02-2021 дата публикации

Minimization of Noise in Optical Data Capture for Liquids

Номер: US20210033525A1
Автор: Jacob Y Wong, Thomas Campbell
Принадлежит: Liquid Sensing Inc

A process and sensor system useful for determining a concentration of a targeted molecule M (such as glucose) within a given time period in a liquid sampling matrix wherein the sample volume is configured so that a sampling error caused by changes of the targeted molecule passing in and out of the sample volume is approximately the same or less than a measurement error caused by an accuracy limit of electronic components and optical elements used in the sensor system.

Подробнее
Номер записи: 29
08-02-2018 дата публикации

TDLAS Architecture for Widely Spaced Wavelengths

Номер: US20180038788A1
Автор: Andrew D. Sappey, Bernard Patrick Masterson
Принадлежит: John Zink Co Llc

A system for widely spaced wavelength tunable diode laser absorption spectroscopy includes at least a first and second tunable diode laser generating laser light at a first and second wavelength, wherein laser light of the first and second wavelengths cannot co-propagate efficiently on the same single-mode fiber. A first fiber may be configured to carry light in the first wavelength, and a second fiber configured to carry light in the second wavelength. A fiber bundle may be formed from the distal ends of the first and second fibers stripped of their respective coatings, and arranged with their claddings adjacent to each other. One or more pitch heads are configured to project respective beams of laser light from the fiber bundle through a measurement zone. One or more catch heads located across the measurement zone receive the respective beams and direct the respective beams onto at least one sensor.

Подробнее
Номер записи: 30
07-02-2019 дата публикации

METHOD, APPARATUS AND SOFTWARE FOR DETECTION AND LOCALIZATION OF HIDDEN DEFECTS IN OPTICALLY DIFFUSE MEDIA

Номер: US20190041319A1
Автор: Kho Esther, Maria Sterenborg Henricus Josephus Cornelus, Ruers Theodoor Jacques Marie
Принадлежит:

In a method and apparatus, a property of an optically diffuse medium including a first optical absorber having a first concentration and a second optical absorber having a second concentration is determined. A surface area of the medium is imaged at multiple wavelengths around an isosbestic wavelength of the first absorber and the second absorber. A reflectance spectrum of the medium at the surface area at the multiple wavelengths is determined. A derivative of the determined reflectance spectrum around the isosbestic wavelength is determined. From the derivative, a concentration ratio of the first concentration and the second concentration is estimated. 1. A method of determining a property of an optically diffuse medium , the medium comprising a first optical absorber having a first concentration and a second optical absorber having a second concentration , the method comprising the steps of:(a) imaging a surface area of the medium at multiple wavelengths around an isosbestic wavelength of the first absorber and the second absorber;(b) determining a reflectance spectrum of the medium at the surface area at the multiple wavelengths;(c) determining a derivative of the determined reflectance spectrum around the isosbestic wavelength; and(d) estimating a concentration ratio (ψ) of the first concentration and the second concentration from the derivative of the determined reflectance spectrum around the isosbestic wavelength,wherein the concentration ratio (ψ) is determined using the partial derivative of a first molar absorption coefficient of the first absorber as a function of the wavelength, and the partial derivative of a second molar absorption coefficient of the second absorber as a function of the wavelength, both taken at a wavelength at which the first molar absorption coefficient and the second molar absorption coefficient are equal.3. The method according to claim 1 , wherein the derivative of the determined reflectance spectrum around the isosbestic ...

Подробнее
Номер записи: 31
07-02-2019 дата публикации

Water content of a part of plant evaluation method and water content of a part of plant evaluation apparatus

Номер: US20190041325A1
Автор: Takeshi Fujiyama, Yuuji Terashima
Принадлежит: Panasonic Intellectual Property Management Co Ltd

A water content evaluation apparatus which evaluates water content of a part of a plant is provided. A water content at each of irradiation positions of the part of the plant is calculated based on a first reflection light of a laser reference beam, having a first wavelength that is not absorbed by water, that is reflected at all the irradiation positions of the plant and a second reflection light of a laser measuring beam, having a second wavelength that is absorbed by water, that is reflected at all the irradiation positions of the plant. Irradiation positions of the plant in which the water content is equal to or larger than at least one predetermined threshold level are displayed, in at least one corresponding predetermined color.

Подробнее
Номер записи: 32
06-02-2020 дата публикации

Spectrometric Measuring Head for Forestry, Agricultural and Food Industry Applications

Номер: US20200041340A1
Автор: Klein Helge, Schade Peter
Принадлежит:

A spectrometric measuring head for forestry, agricultural and food industry applications comprises a housing having a window and a spectrometer that is arranged inside the housing and comprises a dispersive element and a sensor, a first light source for exposing a sample to light, which reaches the spectrometer through the window after having been transmitted and/or reflected by the sample, and a standard that can be exposed to light to provide a reference for the spectrometer, which standard can be exposed to light by a light source arranged in the housing. 1. A spectrometric measuring head for forestry , agricultural and food industry applications , comprising:a housing having a window and a spectrometer that is arranged inside the housing and comprises a dispersive element and a sensor,a first light source for exposing a sample to a first light, which reaches the spectrometer through the window after having been transmitted from the first light source through the window and reflected by the sample, anda standard configured to be exposed to a second light to provide a reference for the spectrometer,a partially transmissive mirror arranged between the window and the spectrometer, configured to provide an optical transmission for the first light reflected by the sample toward the spectrometer, and configured to reflect the second light reflected from the standard into the spectrometer;a filter having an electrically controllable transmissivity and arranged between the partially transmissive mirror and the standard; andwherein the standard is configured to be exposed to the second light by the second light source arranged in the housing.2. The spectrometric measuring head according to claim 1 , wherein the first light source is arranged inside or outside the housing.3. The spectrometric measuring head according to claim 1 , wherein the spectrometer is designed as a micro-electromechanical system (MEMS).4. The spectrometric measuring head according to claim 1 , ...

Подробнее
Номер записи: 33
18-02-2016 дата публикации

SAMPLE TEST METHOD, MICROFLUIDIC DEVICE, AND TEST DEVICE

Номер: US20160047740A1
Автор: CHO Euy Hyun, Kim Ha Na, KIM Kui Hyun, LEE Beom Seok, PARK Joo Hee, PARK Sang Bum, Park Sung Ha, SONG Kyung Mi
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

A sample test method, microfluidic device, and test device efficiently and accurately compensates for interference of an interfering substance present in a sample using optical measurement without addition of a separate reagent for detecting the interfering substance. The sample test method includes: measuring an optical characteristic value of a target substance present in a sample; measuring an optical characteristic value of an interfering substance present in the sample; and determining a concentration of the target substance for which interference of the interfering substance is compensated for based on the optical characteristic value of the interfering substance. 1. A sample test method comprising:measuring an optical characteristic value of a target substance present in a sample;measuring an optical characteristic value of an interfering substance present in the sample; anddetermining a concentration of the target substance for which interference of the interfering substance is compensated for based on the optical characteristic value of the interfering substance.2. The sample test method of claim 1 , wherein the determining the concentration of the target substance for which interference of the interfering substance is compensated for comprises:compensating the optical characteristic value of the target substance using the optical characteristic value of the interfering substance; anddetermining the concentration of the target substance based on the compensated optical characteristic value.3. The sample test method of claim 2 , wherein the compensating the optical characteristic value of the target substance comprises:applying a fluctuation coefficient to the optical characteristic value of the interfering substance to obtain an application result, and then subtracting or adding the application result from or to the optical characteristic value of the target substance.4. The sample test method of claim 1 , wherein the measuring the optical characteristic ...

Подробнее
Номер записи: 34
16-02-2017 дата публикации

DEVICE FOR ANALYSING A SPECIMEN AND CORRESPONDING METHOD

Номер: US20170045397A1
Автор: Heussler Sascha Pierre, Schmidt Daniel
Принадлежит: NATIONAL UNIVERSITY OF SINGAPORE

A device for analysing a specimen is disclosed. The device comprises a first polarizer for polarizing a first beam of electromagnetic radiation; an optical device for directing the polarized beam of electromagnetic radiation at the specimen to enable interaction between the polarized beam of electromagnetic radiation and the specimen to cause generation of a second beam of electromagnetic radiation; a plurality of second polarizers for dividing the wavefront of the second beam of electromagnetic radiation into a plurality of beams of electromagnetic radiation polarized with different polarization states; and at least one spectrometer for analysing respective electromagnetic spectrums of the plurality of polarized beams of electromagnetic radiation to enable the specimen to be characterised. A related method is also disclosed. 1. A device for analysing a specimen , comprising:a first polarizer for polarizing a first beam of electromagnetic radiation;an optical device for directing the polarized beam of electromagnetic radiation at the specimen to enable interaction between the polarized beam of electromagnetic radiation and the specimen to cause generation of a second beam of electromagnetic radiation;a plurality of second polarizers for dividing the wavefront of the second beam of electromagnetic radiation into a plurality of beams of electromagnetic radiation polarized with different polarization states; andat least one spectrometer for analysing respective electromagnetic spectrums of the plurality of polarized beams of electromagnetic radiation to enable the specimen to be characterised.2. The device of claim 1 , wherein the device further includes a beam source arranged to generate the first beam of electromagnetic radiation selected from the group consisting of ultraviolet radiation claim 1 , visible light claim 1 , infrared radiation and Terahertz radiation.3. The device of claim 2 , wherein the beam source is further arranged to generate the first beam of ...

Подробнее
Номер записи: 35
16-02-2017 дата публикации

SAMPLE ANALYSIS METHODS

Номер: US20170045441A1
Автор: NCIRI Mejdi
Принадлежит:

The invention generally relates to methods for determining a concentration of at least one target analyte in a heterogeneous sample and methods for detecting a condition. In certain aspects, the inventions provides methods that involve illuminating a heterogeneous sample, such as a biological sample, including at least one target analyte with polychromatic light, receiving luminous data of the heterogeneous sample and the at least one target analyte with a detector without splitting the polychromatic light into individual wavelengths and generating spectral data therefrom. The spectral data is then converted into a concentration of the at least one target analyte in the biological sample by comparing the spectral data to a database comprising known spectra already associated with concentration levels. 1. A method for determining a concentration of at least one target analyte in a heterogeneous sample , the method comprising:illuminating a heterogeneous sample comprising at least one target analyte with polychromatic light;receiving a luminous signal of the heterogeneous sample and the at least one target analyte with a detector without splitting the polychromatic light into individual wavelengths;generating spectral data from the received luminous signal; andconverting the spectral data into a concentration of the at least one target analyte in the heterogeneous sample by comparing the spectral data to a database comprising known spectra already associated with concentration levels of the target analyte.2. The method of claim 1 , wherein the heterogeneous sample is at least one selected from the group consisting of a biological sample claim 1 , an environmental sample claim 1 , a food product sample claim 1 , and a beverage product sample.3. The method of claim 2 , wherein the biological sample is a human tissue or body fluid sample4. The method of claim 3 , wherein the body fluid sample is a blood sample.5. The method of claim 2 , wherein the body fluid sample is a ...

Подробнее
Номер записи: 36
19-02-2015 дата публикации

Biochemical analyzing system and light module thereof

Номер: US20150049328A1
Автор: Chung-hsien Tsai
Принадлежит: PROTECTLIFE INTERNATIONAL BIOMEDICAL Inc

A light module for a biochemical analyzing system includes a halogen light source emitting light beams, which are guided through a first light path and a second light path and then combined to go through a first beam splitter, so as to analyze a biochemical sample. The first light path includes a plurality of reflective mirrors and a first filter lens, and the first filter lens is used to attenuate an orange band light of the halogen light source. The second light path includes a second filter lens, and the second filter lens is used to attenuate the lights of the halogen light source except the ultraviolet light band.

Подробнее
Номер записи: 37
15-02-2018 дата публикации

System and Method for Background Removal in Spectrometry System

Номер: US20180045694A1
Автор: Behnke Peter Paul, Spartz Martin L., Wyatt Eddie Dean
Принадлежит:

An analysis system includes a separation system that provides compounds to a sample cell of a spectrometric system. The system analyzes spectral information from the spectrometric system by optimizing retention windows for the compounds and identifies quantities of the compounds by comparing spectral information within and outside the respective retention windows. 1. A method for analyzing sample spectra of a sample from a spectrometric system , the method comprising:shifting retention windows and/or shifting lower bounds of the retention windows and/or shifting upper bounds of the retention windows;comparing the sample spectra from the shifted retention windows to reference spectra for compounds of interest in the sample; andupdating the retention windows used to analyze the sample.2. The method of claim 1 , wherein shifting the retention windows includes shifting the entire retention windows; and wherein comparing the sample spectra comprises regressing the reference spectra over the sample spectra from the shifted retention windows and rating fit.3. The method of claim 1 , wherein shifting the retention windows includes separately shifting the lower bounds of the retention windows and shifting the upper bounds of the retention windows; and wherein comparing the sample spectra comprises regressing the reference spectra over the sample spectra from the shifted retention windows and rating fit.4. The method of claim 1 , further comprising validating the shifted retention windows.5. The method of claim 4 , wherein validating the shifted retention windows comprises:calculating retention times for compounds based on the shifted retention windows;comparing the calculated retention times against expected retention times for the compounds; andanalyzing differences between the calculated retention times against expected retention times for different compounds to validate the shifted retention windows.6. The method of claim 4 , wherein validating the shifted retention ...

Подробнее
Номер записи: 38
03-03-2022 дата публикации

SPECTROSCOPIC ANALYSIS DEVICE, OPTICAL SYSTEM, AND METHOD

Номер: US20220065697A1
Автор: HARA Risa, MURAYAMA Kodai, Saruya Toshiyuki, WATANABE Fumie
Принадлежит: YOKOGAWA ELECTRIC CORPORATION

A spectroscopic analysis device includes: a film that contacts a sample subject to spectroscopic analysis; a first irradiator that irradiates a first irradiation light having transition energy to decompose attached material attached to a boundary surface of the film; and an optical waveguide that transmits the first irradiation light irradiated from the first irradiator. A first evanescent wave, based on the first irradiation light, is generated on a front surface of the optical waveguide, and is then projected on an attached region of the attached material. 1. A spectroscopic analysis device , comprising:a film that contacts a sample subject to spectroscopic analysis;a first irradiator that irradiates a first irradiation light having transition energy to decompose attached material attached to a boundary surface of the film; andan optical waveguide that transmits the first irradiation light irradiated from the first irradiator, whereina first evanescent wave, based on the first irradiation light, is generated on a front surface of the optical waveguide, and is then projected on an attached region of the attached material.2. The spectroscopic analysis device according to claim 1 , whereinthe optical waveguide comprises a reflective surface that completely reflects the first irradiation light incident on the optical waveguide, andthe first irradiation light incident on the optical waveguide is transmitted while being completely reflected by the reflective surface in the optical waveguide.3. The spectroscopic analysis device according to claim 1 , further comprising:a first detector that detects a first measured light emitted from the optical waveguide, whereinthe first measured light is based on the first irradiation light irradiated by the first irradiator, andthe first measured light comprises first information of an absorption spectrum of the attached material.4. The spectroscopic analysis device according to claim 3 , further comprising: obtains, from the first ...

Подробнее
Номер записи: 39
14-02-2019 дата публикации

SAMPLE ANALYZER AND SAMPLE ANALYZING METHOD

Номер: US20190049379A1
Автор: KONISHI Yusuke, MATSUMOTO Shohei, Yamada Kazuhiro
Принадлежит:

Disclosed is a sample analyzer that includes: a measurement unit configured to apply light to a measurement specimen containing a plurality of kinds of target substances each labeled with fluorescence, and detect a plurality of kinds of fluorescences having different wavelengths; and a processing unit configured to analyze the plurality of kinds of target substances based on a detection result from the measurement unit, and information, on a color of fluorescence, which is set to be variable so as to correspond to the plurality of kinds of target substances. 1. A sample analyzer comprising:a measurement unit configured to apply light to a measurement specimen containing a plurality of kinds of target substances, each labeled with fluorescence, and to detect a plurality of kinds of fluorescences having different wavelengths; anda processing unit configured to analyze the plurality of kinds of target substances based on a detection result from the measurement unit, and information, on a color of fluorescence, which is set to bewherein the color of fluorescence is a variable so as to correspond that corresponds to each of the plurality of kinds of target substances.2. The sample analyzer of claim 1 , comprising a display unit claim 1 , wherein the processing unit causes the display unit to display an input screen for receiving input of the information on the color of the fluorescence such that the information on the color of the fluorescence corresponds to the target substance.3. The sample analyzer of claim 2 , wherein the input screen comprises a plurality of sets each including an item for the target substance and an item for inputting the information on the color of the fluorescence.4. The sample analyzer of claim 2 , whereinthe target substance is related to a measurement item,the processing unit receives input of the measurement item, andthe input screen comprises a set of an item for the target substance corresponding to the inputted measurement item, and an ...

Подробнее
Номер записи: 40
14-02-2019 дата публикации

FERMENTATION GAS SENSOR SYSTEM

Номер: US20190049388A1
Автор: JENSEN Kristophor Ray
Принадлежит: BLACK JOULE, LLC

A gas sensor system for use in an exhaust gas tube, the system having at least two separate optical sensor assemblies that are separately positioned across the exhaust gas tube from one another, wherein the optical sensor assemblies each comprise a pair of light sources and a pair of light receivers such that light from each of the multiple light sources is received by each of the four light receivers, thereby generating multiple sets of optical measurements. 2. The gas sensor system of claim 1 , wherein:the first and second light sources in the first optical sensor assembly direct light to the first and second light receivers in the second optical sensor assembly, andthe first and second light sources in the second optical sensor assembly direct light to the first and second light receivers in the first optical sensor assembly.3. The gas sensor system of claim 2 , wherein:the first and second optical sensor assemblies generate four sets of optical measurements.4. The gas sensor system of claim 1 , wherein the first and second optical sensor assemblies are mounted on separate printed circuit boards.5. The gas sensor system of claim 1 , wherein the first and second optical sensor assemblies further comprise:a static pressure sensor;a dynamic pressure sensor; anda temperature sensor.6. The gas sensor system of claim 1 , wherein the first and second optical sensor assemblies further comprise:a methane sensor; andan acetic acid sensor.7. The gas sensor system of claim 1 , wherein each of the first and second sensor assemblies further comprise:a microcontroller;a power supply; anda wired or wireless data transmitter configured to transmit measured data to the Cloud.8. The gas sensor system of claim 1 , wherein a third sensor assembly is positioned intermediate the first and second sensor assemblies on the inner side of the exhaust gas tube.9. The gas sensor system of claim 1 , wherein the first and second light sources in each optical assembly comprise at least one of:a ...

Подробнее
Номер записи: 41
26-02-2015 дата публикации

Blood analysis

Номер: US20150055121A1
Автор: Tommy Forsell
Принадлежит: Individual

The invention discloses a blood analyzing device ( 100 ) comprising a holder ( 110 ) arranged for carrying a container ( 10 ) having a cuvette ( 20 ) containing a blood sample ( 30 ). The container ( 10 ) is positioned in the holder ( 110 ) so that a longitudinal axis ( 60 ) of the cuvette ( 20 ) is angled relative a horizontal axis ( 70 ). A light source ( 120 ) provides light ( 40 ) into the sample ( 30 ) and a detector ( 130 ) detects the output light ( 50 ) from a sub-portion of the blood sample ( 30 ). Kinetic information indicative of the change in hemoglobin concentration in a measuring volume ( 32, 34 ) is determined by a Hb processor ( 145 ) from the detected output light ( 50 ). An ESR processor ( 140 ) determines the erythrocyte sedimentation rate of the sample ( 30 ) based on the kinetic information.

Подробнее
Номер записи: 42
25-02-2021 дата публикации

OPTICAL GAS SENSOR

Номер: US20210055212A1
Автор: DUPREZ Helene
Принадлежит:

A gas sensor comprises a chamber configured to receive a gas; a light source configured to emit a light wave propagating through the chamber in an emission cone; a measurement photodetector and a reference photodetector, each configured to detect a light wave emitted by the light source and having passed through the chamber. The chamber extends between two transverse walls, arranged opposite one another and connected to one another by a peripheral wall extending therebetween, about a longitudinal axis (Z), and comprising a first reflective segment configured to receive a first portion of the emission cone to reflect it toward the measurement photodetector, thus forming a measurement cone converging toward the measurement photodetector. A second reflective segment of the peripheral wall is configured to receive a second portion of the emission cone to reflect it toward the reference photodetector, thus forming a reference cone converging toward the reference photodetector. 1. A gas sensor comprising a chamber configured to receive gas , the gas sensor further comprising:a light source, configured to emit a light wave that propagates through the chamber in an emission cone; anda measurement photodetector and a reference photodetector, each being configured to detect a light wave emitted by the light source and having passed through the chamber; a first reflective segment, configured to receive a first portion of the emission cone in order to reflect it toward the measurement photodetector, thus forming a measurement cone that converges toward the measurement photodetector, the first reflective segment following, in a transverse plane, perpendicular to the longitudinal axis, a first ellipse, an apex of the emission cone being placed at a first focus of the first ellipse; and', 'a second reflective segment, configured to receive a second portion of the emission cone in order to reflect it toward the reference photodetector, thus forming a reference cone that converges ...

Подробнее
Номер записи: 43
25-02-2021 дата публикации

SLOPE SPECTROSCOPY STANDARDS

Номер: US20210055315A1
Автор: Harrison Craig, Salerno Mark, Shih I-Tsung
Принадлежит:

The present invention relates generally to a slope spectroscopy standards and methods of making slope spectroscopy standards, specifically standards and methods of developing standards specifically for variable pathlength (slope) measurements. 1. A method of making a slope spectroscopy standard for a compound comprising:selecting a compound;determining the slope at a predetermined concentration of the compound;determining a concentration of a standard which corresponds to the compound slope by using variable path length spectroscopy wherein the compound and the standard are different compounds and wherein the compound and the standard have absorbance spectra that share a common absorbance wavelength; andmaking a standard of an appropriate concentration which provides a slope measurement that corresponds to that of the compound.2. The method of wherein the standard is in an aqueous solution.3. The method of wherein the standard has a slope measurement of from about 0.01 to 500.4. The method of wherein the standard has a slope measurement of from about 1 to 500.5. The method of wherein the standard is a methylxanthine.6. The method of claim 5 , wherein the methylxanthine is selected from the group consisting of caffeine claim 5 , aminophylline claim 5 , IBMX claim 5 , paraxanthine claim 5 , pentoxifylline claim 5 , theobromine claim 5 , and theophylline7. The method of wherein the methylxanthine is caffeine.8. The method of wherein the standard is selected from the group consisting of NaCl claim 1 , KHP claim 1 , KCl and KCrO.9. The slope spectroscopy standard of wherein the standard has an uncertainty value of from about 0.1% to about 5%.10. A method of making a slope spectroscopy standard for a combination of a particular ratio of first compound to second compound in a combination of compounds comprising:determining the ratio of the first compound to the second compound in a combination of the compoundsdetermining a concentration of first substance which absorbs ...

Подробнее
Номер записи: 44
13-02-2020 дата публикации

Dmd based uv absorption detector for liquid chromatography

Номер: US20200049674A1
Автор: Aditya Shankar Prasad, Anthony C. Jeannotte, Daniel Gillund, Saksham Saxena
Принадлежит: Water Technologies Corp, Waters Technologies Corp

A detector for use in liquid chromatography is provided. The detector includes a light delivery system comprising a light source that emits one or more spectral lines of light of a light spectrum. The detector has an entrance slit configured to receive the one or more spectral lines of light and a wavelength selection module comprising a digital micro-mirror device. The digital micro-mirror device is configured to redirect the one or more spectral lines of light to a flow cell. The flow cell is optically connected to the wavelength selection module.

Подробнее
Номер записи: 45
01-03-2018 дата публикации

SYSTEM AND METHOD FOR PREPARING AROMATIC DERIVATIVE

Номер: US20180057429A1
Автор: HSU Chan-Chia, HSUEH SHENG-YAO
Принадлежит:

A system for preparing an aromatic derivative is provided, including: a photo-bromination reaction section for performing a photocatalytic reaction of an aromatic hydrocarbon and a brominating agent to form an aromatic hydrocarbon bromide; a substitution reaction section for performing a substitution reaction of the an aromatic hydrocarbon bromide from the photo-bromination reaction section with an alkali base compound or an alkali carboxylate compound to form an aromatic derivative; and a regeneration unit for reacting an alkali metal bromide formed by the substitution reaction section with an acid to form a hydrobromic acid. The regeneration unit is in fluid communication with the photo-bromination reaction section, such that the hydrobromic acid is recycled to the photo-bromination reaction section. A method for preparing the aromatic derivative is also provided. 1. A system for preparing an aromatic derivative , comprising:a photo-bromination reaction section for performing a photocatalytic reaction of an aromatic hydrocarbon and a brominating agent to form an aromatic hydrocarbon bromide;a substitution reaction section for performing a substitution reaction of the aromatic hydrocarbon bromide from the photo-bromination reaction section with an alkali base compound or an alkali carboxylate compound to form an aromatic derivative; anda regeneration unit for reacting an alkali metal bromide formed by the substitution reaction section with an acid to form a hydrobromic acid, wherein the regeneration unit is in fluid communication with the photo-bromination reaction section, such that the hydrobromic acid is recycled to the photo-bromination reaction section.2. The system for preparing an aromatic derivative as claimed in claim 1 , wherein the photo-bromination reaction section and the substitution reaction section are located in the same reactor.3. The system for preparing an aromatic derivative as claimed in claim 1 , wherein the photo-bromination reaction section ...

Подробнее
Номер записи: 46
21-02-2019 дата публикации

Spectrometric Measuring Head for Forestry, Agricultural and Food Industry Applications

Номер: US20190056265A1
Автор: Klein Helge, Schade Peter
Принадлежит:

A spectrometric measuring head for forestry, agricultural and food industry applications comprises a housing having a window and a spectrometer that is arranged inside the housing and comprises a dispersive element and a sensor, a first light source for exposing a sample to light, which reaches the spectrometer through the window after having been transmitted and/or reflected by the sample, and a standard that can be exposed to light to provide a reference for the spectrometer, which standard can be exposed to light by a light source arranged in the housing. 1. A spectrometric measuring head for forestry , agricultural and food industry applications , comprising:a housing having a window and a spectrometer that is arranged inside the housing and comprises a dispersive element and a sensor,a first light source for exposing a sample to light, which reaches the spectrometer through the window after having been transmitted or reflected by the sample, anda standard that can be exposed to light to provide a reference for the spectrometer,characterized in that the standard can be exposed to light by a light source arranged in the housing.2. The spectrometric measuring head according to claim 1 , wherein the first light source is arranged inside or outside the housing.3. The spectrometric measuring head according to claim 1 , wherein a partially transmissive mirror is arranged on the window or between the window and the spectrometer and reflects light reflected from the standard into the spectrometer.4. The spectrometric measuring head according to claim 1 , wherein a filter having an electrically controllable transmissivity is arranged between a second light source and the spectrometer and more particularly between a mirror and the standard.5. The spectrometric measuring head according to claim 1 , wherein the spectrometer is designed as a micro-electromechanical system (MEMS).6. The spectrometric measuring head according to claim 1 , wherein an optical axis of the ...

Подробнее
Номер записи: 47
21-02-2019 дата публикации

DRIED BLOOD SAMPLE ANALYSIS

Номер: US20190056314A1
Автор: Aalders Maurice, Capiau Sara, Stove Christophe, Wilk Leah
Принадлежит:

A non-destructive method of estimating hematocrit (Hct) of whole blood from a dried blood sample prepared from the whole blood, the method comprising: a) determining the amount of hemoglobin derivatives comprising oxyhemoglobin, methemoglobin and hemichrome (total hemoglobin) in a dried blood sample, wherein the sum of the amounts of the hemoglobin derivatives remains constant in the dried blood sample in function of time, and b) estimating the hematocrit from the sum of the amounts of the hemoglobin derivatives, wherein the hematocrit is estimated using a calibration curve providing a correlation between hematocrit and the amount of the hemoglobin derivatives in a dried blood sample. The amount of the hemoglobin derivatives is preferably determined by measuring the reflectance, absorbance, or transmittance of the dried blood sample at the quasi-isosbestic point of the hemoglobin derivatives about 589 nm or at multiple wavelengths within the range of 450 to 750 nm. 124-. (canceled)25. A non-destructive method of estimating hematocrit (Hct) of whole blood from a dried blood sample prepared from the whole blood , the method comprising: wherein the total amount of said hemoglobin derivatives in a dried blood sample is determined by measuring the reflectance, absorbance, or transmittance of the dried blood sample at the quasi-isosbestic point of said hemoglobin derivatives, or', 'wherein the total amount of said hemoglobin derivatives in a dried blood sample is determined by calculating the sum of the amounts of each of oxyhemoglobin, met-hemoglobin and hemichrome, wherein the amount of each of oxyhemoglobin, met-hemoglobin and hemichrome is determined by measuring the reflectance, absorbance, or transmittance of the dried blood sample at multiple wavelengths, and comparing the measured spectrum with reference spectra of the respective hemoglobin derivatives; and, 'a) determining the total amount of hemoglobin derivatives comprising oxyhemoglobin, met-hemoglobin and ...

Подробнее
Номер записи: 48
21-02-2019 дата публикации

DEVICE AND METHOD FOR MEASURING TAR IN A TAR-ENVIRONMENT

Номер: US20190056317A1
Автор: CLAUSEN Sønnik, FATEEV Alexander
Принадлежит: DANMARKS TEKNISKE UNIVERSITET

The present disclosure describes a device and corresponding method for measuring tar in a tar environment, e.g., a tar producing environment such as a stove or a combustion engine, based on UV absorption spectroscopy. A first measurement along an optical path in the tar environment is performed at a wavelength less than 340 nm at which both tar and non-tar elements absorb. This measurement is compensated for non-tar absorption by means of a second measurement at a wavelength equal to or greater than 340 nm at which tar does not absorb. From the non-tar compensated absorbance value a measure of tar in the tar environment is derived and an air intake in the tar environment is regulated based on the measure of tar. 129-. (canceled)30. A device for measuring tar inside a tar-environment , comprising:at least one light generating element configured for generating light, a first wavelength less than 340 nm, whereby light is absorbed by both tar-elements and non-tar elements; and', 'a second wavelength equal to or greater than 340 nm, whereby light is absorbed by non-tar elements, and, 'the device being configured such that the light hasthe device being further configured such that the light has an optical path length through the tar-environment; a first light signal from the light having the first wavelength less than 340 nm,', 'a second light signal from the light having the second wavelength equal to or greater than 340 nm;, 'at least one light detection element for receiving the light from the at least one light generating element and configured for obtaininga processing unit configured for deducing a first absorbance value from the first light signal and configured for deducing a second absorbance value from the second light signal and relating the second absorbance value to the first absorbance value, thereby obtaining an non-tar compensated absorbance value, and the processing unit further configured for correlating the non-tar compensated absorbance value to a ...

Подробнее
Номер записи: 49
02-03-2017 дата публикации

Apparatuses and methods for performing a light-absorption measurement on a test sample and a compliance measurement on a reference sample

Номер: US20170059478A1
Автор: Chun-Hung Kuo, Tomasz Pol, William Alan MARKS
Принадлежит: Mettler Toledo AG

Apparatuses and methods are disclosed for performing a light-absorption measurement on a test sample and a compliance measurement on a reference sample. A method includes moving a reference sample receptacle carrier of an apparatus to position a first reference sample receptacle received in the carrier at a second position in a light path, directing light from an illumination system to a detection system along the light path to perform a light-absorption measurement on a first reference sample at the second position, moving the carrier to position the first receptacle out of the light path, placing a test sample receptacle in a test sample receptacle holder of the apparatus in the light path at a first position different from the second position, and directing light along the light path to perform a light-absorption measurement on a test sample in the test sample receptacle holder at the first position.

Подробнее
Номер записи: 50
28-02-2019 дата публикации

HYPERSPECTRAL TECHNOLOGY FOR ASSESSING AND TREATING DIABETIC FOOT AND TISSUE DISEASE

Номер: US20190059787A1
Автор: Brand Derek, Freeman Jenny E., Hopmeier Michael, Panasyuk Svetlana, Schomacker Kevin
Принадлежит:

This invention relates generally to an index map comprising both pressure and perfusion information from a diabetic patient foot for the purpose of treatment. The index map may also be a map of perfusion and/or metabolism of the tissue (reflecting oxygen delivery and oxygen extraction, obtained by thermal imaging, hyperspectral imaging, or duplex ultrasound, MRA, CT or laser Doppler imaging. This information aids treatment in prevention of diabetic foot ulceration and amputation and in treatment of tissue compromise to prevent tissue loss in other body regions. 157-. (canceled)58. A method for designing a prosthetic or orthotic device for treatment of a tissue of a subject , the method comprising:(A) obtaining a gradient map of the tissue of the subject, wherein the gradient map comprises information about tissue oxygenation, tissue oxygen extraction, tissue metabolism, or tissue perfusion of the tissue;(B) determining a pressure or stress applied to the tissue;(C) identifying one or more areas of the tissue that are at risk for disease formation or disease progression based on the gradient map, or the pressure or stress applied to the tissue; and(D) designing the prosthetic or orthotic device to redistribute the pressure or stress across the tissue, wherein the redistribution of the pressure or stress across the tissue reduces the pressure or the stress applied to the one or more identified areas of the tissue that are at risk for disease formation or disease progression.59. The method of claim 58 , wherein the gradient map of the tissue of the subject is a hyperspectral image.60. The method of claim 58 , wherein the gradient map of the tissue of the subject is paired with a spatial map of the pressure or stress applied to the tissue to form a composite image claim 58 , wherein the identifying of the one or more areas of the tissue that are at risk for disease formation or disease progression is based on the composite image.61. The method of claim 58 , wherein the ...

Подробнее
Номер записи: 51
04-03-2021 дата публикации

PHOTOABSORPTION MICROSCOPY USING ELECTRON ANALYSIS

Номер: US20210066030A1
Автор: Majumdar Arunava, MARTIS Joel, Zhang Ze
Принадлежит:

A method for chemical identification of a sample having nanostructures includes the steps of irradiating the surface at wavelengths for each of a first and a second of the nanostructures that are uniquely absorbed by each of the first nanostructure and the second nanostructure such that each is excited to modulate at a first or a second nanostructure frequency, respectively. The method continues with the steps of irradiating the surface with electron beams incident on each of the first and second nanostructure, wherein at least one of secondary electrons, backscattered electrons and transmitted electrons are modulated at the frequency corresponding to each of the first and second nanostructure frequencies. A chemical map of the sample at an atomic scale is then created. A microscope is provided to carry out the method. 1. A method for chemical identification of a surface of a sample having a plurality nanostructures , each nanostructure having different radiation absorption spectra , the method comprising:(a) irradiating the surface at a first wavelength for a first of said plurality of nanostructures that is uniquely absorbed by the first nanostructure such that the first nanostructure is excited to modulate at a frequency corresponding to the first nanostructure frequency;(b) irradiating the surface at a second wavelength for a second of said plurality of nanostructures that is uniquely absorbed by the second nanostructure such that the second nanostructure is excited to modulate at a frequency corresponding to the second nanostructure;(c) irradiating the surface with an electron beam, wherein when the electron beam is incident on the first nanostructure, wherein at least one of secondary electrons, backscattered electrons and transmitted electrons are modulated at the frequency corresponding to the first nanostructure frequency;(d) irradiating the surface with the electron beam, wherein when the electron beam is incident on the second nanostructure, wherein at ...

Подробнее
Номер записи: 52
17-03-2022 дата публикации

EVALUATING SURFACES

Номер: US20220080734A1
Автор: Bordone Maurizio, GARCIA ALVAREZ Ana Cristina, Perez Garcia Alexander Jose
Принадлежит: Hewlett-Packard Development Company, L.P.

In an example, a surface inspection apparatus includes a light source to illuminate a portion of a surface in a print apparatus, a light detection apparatus and processing circuitry. The light detection apparatus may receive diffusely reflected light and specularly reflected light from the portion of the surface, and may comprise a detection element for detecting the specularly reflected light. The processing circuitry may comprise a comparison module to determine a relationship between an intensity of the detected diffusely reflected light and the detected specularly reflected light and a quality module to evaluate if the surface meets a quality criterion based on the relationship. 1. A surface inspection apparatus comprising:a light source to illuminate a portion of a surface in a print apparatus;a light detection apparatus to receive diffusely reflected light and specularly reflected light from the portion of the surface, wherein the light detection apparatus comprises a detection element for detecting the specularly reflected light; and a comparison module to determine a relationship between an intensity of detected diffusely reflected light and the detected specularly reflected light; and', 'a quality module to evaluate if the surface meets a quality criterion based on the relationship., 'processing circuitry comprising2. An apparatus as claimed in wherein the surface is the surface of a web wipe for cleaning a printhead of a printing apparatus.3. An apparatus as claimed in wherein the quality module is to determine if the surface meets a quality criterion by determining a distance between the apparatus and the portion of the surface using the relationship between the intensity of the detected diffusely reflected light and the detected specularly reflected light.4. An apparatus as claimed in wherein the processing circuitry further comprises:a thickness determination module to determine the thickness of the surface based on the determined distance between the ...

Подробнее
Номер записи: 53
28-02-2019 дата публикации

METHODS AND SYSTEMS FOR OBTAINING HIGH-RESOLUTION SPECTRAL DATA OF FORMATION FLUIDS FROM OPTICAL COMPUTING DEVICE MEASUREMENTS

Номер: US20190063215A1
Автор: Chen Dingding, DAI BIN, Jones Christopher Michael
Принадлежит:

A system includes an optical computing device having an optical multiplexer that receives a sample light generated by an optical interaction between a sample and an illumination light is provided. The system includes sensing elements that optically interact with the sample light to generate modified lights, and a detector that measures a property of the modified lights separately. Linear and nonlinear models for processing data collected with the above system to form high-resolution spectra are also provided. Methods for designing optimal optical multiplexers for optimal reconstruction of high-resolution spectra are also provided. 1. A system , comprising: an optical multiplexer that receives a sample light generated by an optical interaction between a sample and an illumination light;', 'at least two sensing elements that optically interact with the sample light to generate at least a first modified light and a second modified light; and', 'a detector that measures a property of the first and second modified lights separately to generate a first signal and a second signal, respectively; and, 'an optical computing device that includesa controller comprising a processor and a memory, wherein the processor receives the first and the second signals and determines a spectral data value of the sample light with high spectral resolution.2. The system of claim 1 , further comprising a light source that generates the illumination light claim 1 , wherein the controller transmits commands to the light source to control and modify the illumination light.3. The system of claim 1 , wherein the optical multiplexer separates the first and second modified lights in time.4. The system of claim 1 , wherein the optical multiplexer separates the first and second modified lights in space.5. The system of claim 1 , wherein the first and second modified lights are associated with first and second spectral bands claim 1 , respectively claim 1 , and the first and second spectral bands are ...

Подробнее
Номер записи: 54
17-03-2022 дата публикации

ZINC AND COPPER MEASUREMENT

Номер: US20220082493A1
Автор: Greenawalt Angella Nicholle, Roth Melanie Ann, Young Brendan Easley
Принадлежит:

An embodiment provides a method for measuring zinc and copper in an aqueous sample, including: reducing an aqueous sample containing an amount of zinc and an amount of copper with a reducing agent; buffering the reduced aqueous sample; chelating the amount of copper in the buffered aqueous sample with a copper(I) chelating agent; measuring the amount of copper in the aqueous sample by measuring a first change in intensity of the absorbance of the copper chelated aqueous sample; chelating the amount of zinc in the buffered aqueous sample with a zinc(II) chelating agent; and measuring the amount of zinc in the aqueous sample by measuring a second change in intensity of the absorbance of the zinc chelated aqueous sample. Other aspects are described and claimed. 1. A method for measuring zinc and copper in an aqueous sample , comprising:reducing an aqueous sample containing an amount of zinc and an amount of copper with a reducing agent;buffering the reduced aqueous sample;chelating the amount of copper in the buffered aqueous sample with a copper(I) chelating agent;measuring the amount of copper in the aqueous sample by measuring a first change in intensity of the absorbance of the copper chelated aqueous sample;chelating the amount of zinc in the buffered aqueous sample with a zinc(II) chelating agent; andmeasuring the amount of zinc in the aqueous sample by measuring a second change in intensity of the absorbance of the zinc chelated aqueous sample.2. The method of claim 1 , wherein the reducing agent comprises sodium ascorbate.3. The method of claim 1 , wherein the buffer comprises Tris(hydroxymethyl)aminomethane.4. The method of claim 1 , wherein the copper(I) chelating agent comprises bicinchoninic acid.5. The method of claim 1 , wherein the first change in intensity of the absorbance is proportional to a concentration of the amount of copper in the aqueous sample.6. The method of claim 1 , wherein the zinc(II) chelating agent comprises 2-Carboxy-2′-hydroxy-5′- ...

Подробнее
Номер записи: 55
24-03-2022 дата публикации

TURBIDITY NORMALIZATION ALGORITHM AND METHODS OF REDUCING INTRALIPID/LIPEMIA INTERFERENCE IN HEMOGLOBIN A1c ASSAYS

Номер: US20220091139A1
Автор: Candice ROBINSON, Jian Dai, Justin Jones
Принадлежит: Siemens Healthcare Diagnostics Inc

A method of spectroscopically measuring percent glycated hemoglobin or a glycated hemoglobin:total hemoglobin ratio in a biological sample is disclosed. The method includes the use of a turbidity normalization algorithm to normalize the total hemoglobin concentration calculated from the spectroscopic measurements to substantially remove any turbidity interference therefrom. The turbidity normalization eliminates the negative bias observed with intralipid/lipemia and thus provides a glycated hemoglobin assay with no significant interference from intralipid/lipemia.

Подробнее
Номер записи: 56
16-03-2017 дата публикации

FRESHNESS ESTIMATION METHOD, FRESHNESS ESTIMATION APPARATUS, AND NON-VOLATILE RECORDING MEDIUM

Номер: US20170074784A1
Автор: KONDO NAOSHI, OGAWA Yuuichi, OZAWA Jun, SUZUKI TETSUHITO, WAKITA Yumi
Принадлежит:

A freshness estimation method includes obtaining an absorbance spectrum that is obtained by irradiating an eye of a fish with light having all or part of a wavelength band from 315 nm to 450 nm; and estimating freshness of the fish by using a shape of the obtained absorbance spectrum. 1. A freshness estimation method comprising:emitting, with at least one light source, light having all or part of a wavelength band from 315 nm to 450 nm, and irradiating an eye of a fish with the light;detecting, with a light sensor, an intensity of light reflected from the eye of the fish;calculating, with a processor, an absorbance spectrum based on the intensity of light detected by the light sensor;calculating, with the processor, an absorbance difference by subtracting an absorbance in a certain wavelength in a wavelength band from 315 nm to 380 nm from an absorbance at a certain wavelength in a wavelength band from 410 nm to 430 nm;determining, with the processor, whether the calculated absorbance difference is smaller than a predetermined threshold; andoutputting an indication, via at least one of a visual output device or sound output device, when the calculated absorbance difference is smaller than the predetermined threshold, thereby indicating that the fish is fresh.2. The freshness estimation method according to claim 1 ,wherein the absorbance in the wavelength band from 410 nm to 430 nm is a peak value among absorbances in the wavelength band from 410 nm to 430 nm.3. A freshness estimation apparatus claim 1 , comprising:an absorbance spectrum obtainer that obtains an absorbance spectrum that is obtained by irradiating an eye of a fish with light having all or part of a wavelength band from 315 nm to 450 nm; and calculates an absorbance difference by subtracting an absorbance in a certain wavelength in a wavelength band from 315 nm to 380 nm from an absorbance at a certain wavelength in a wavelength band from 410 nm to 430 nm;', 'determines whether the calculated ...

Подробнее
Номер записи: 57
12-06-2014 дата публикации

Method and apparatus for rapidly cooling a gem, including two stage cooling

Номер: US20140157817A1
Автор: Matt Hall, Ren Lu, Wuyi Wang
Принадлежит: Gemological Institute of America Inc

A cooling apparatus includes a container configured to contain a coolant within a space. The apparatus further includes a cooling block positioned substantially within the space and having a high heat capacity such that the space not occupied by the cooling block is filled with a coolant to a level at or below the top of the cooling block, and a placement structure having high thermal conductivity positioned on top of the cooling block and outside of the space. A method for cooling an object is also provided, which includes inserting a coolant into a container configured to contain the coolant within a space, and placing the object on a placement structure outside the space. For this method, the placement structure has a high thermal conductivity and is coupled to a cooling block, the cooling block having a high heat capacity and positioned substantially within the space. A two-stage cooling apparatus and method is also described.

Подробнее
Номер записи: 58
14-03-2019 дата публикации

MANUFACTORING PROCESS FOR INTEGRATED COMPUTATIONAL ELEMENTS

Номер: US20190076878A1
Автор: Pelletier Michael T., Perkins David L., PRICE James M.
Принадлежит: Halliburton Energy Services, Inc.

Disclosed are methods of fabricating an integrated computational element for use in an optical computing device. One method includes providing a substrate that has a first surface and a second surface substantially opposite the first surface, depositing multiple optical thin films on the first and second surfaces of the substrate via a thin film deposition process, and thereby generating a multilayer film stack device, cleaving the substrate to produce at least two optical thin film stacks, and securing one or more of the at least two optical thin film stacks to a secondary optical element for use as an integrated computational element (ICE). 1. A method , comprising:providing a substrate;depositing multiple optical thin films on a surface of the substrate via a thin film deposition process and thereby generating an optical thin film stack;removing at least a portion of the substrate from the optical thin film stack; andsecuring the optical thin film stack to a secondary optical element for use as an integrated computational element (ICE).2. The method of claim 1 , wherein the substrate is planar.3. The method of claim 2 , wherein the substrate is at least one of mica claim 2 , pyrolitic carbon claim 2 , graphite claim 2 , and graphene.4. The method of claim 1 , wherein depositing the multiple optical thin films on the substrate is preceded by preparing the surface of the substrate either chemically or mechanically.5. The method of claim 1 , wherein securing the optical thin film stack to the secondary optical element is preceded by subdividing the optical thin film stack into multiple optical thin film stacks.6. The method of claim 1 , wherein removing the at least a portion of the substrate from the optical thin film stack is preceded by securing the optical thin film stack to the secondary optical element.7. The method of claim 6 , further comprising chemically reacting the substrate and thereby melting a target surface of the secondary optical element to bond ...

Подробнее
Номер записи: 59
14-03-2019 дата публикации

METHODS OF ASSESSING ANTIBODY-DRUG CONJUGATES

Номер: US20190079005A1
Автор: KULYBA Natallia, SKINNER Andria
Принадлежит:

The present disclosure provides methods of assessing DAR of ADC products that provide advantages over known methods. Specifically, methods of the disclosure can be used in high-throughput applications and/or without having to dilute ADC samples during the assessment. 3. A method of determining a ratio of drug to antibody (DAR) in a sample comprising an antibody-drug conjugate , comprising:placing the sample in a vessel;moving a probe relative to the vessel such that the probe makes contact with the bottom of the vessel;moving the probe relative to the vessel such that the probe moves from the bottom of the vessel through the sample by a predetermined increment such that a preselected path length through the solution is obtained;detecting absorbance of the sample at a first light wavelength (λ1), wherein the first wavelength is a predetermined absorbance maxima of the antibody;repeating steps of moving the probe relative to the sample and taking a measurement at the first wavelength;generating a regression line from the absorbance at the first wavelength and path length such that a slope of the regression line is obtained;determining the concentration of the antibody by dividing the slope of the regression line by an extinction coefficient of the antibody at the first wavelength;detecting absorbance of the sample at a second light wavelength (λ2), wherein the second wavelength is a predetermined absorbance maxima of the drug;repeating steps of moving the probe relative to the sample and taking a measurement at the second wavelength;generating a regression line from the absorbance at the second wavelength and path length such that a slope of the regression line is obtained;determining the concentration of the drug by dividing the slope of the regression line by an extinction coefficient of the drug at the second wavelength; andcalculating a DAR using the determined concentration of drug and the determined concentration of antibody. This application claims priority to ...

Подробнее
Номер записи: 60
23-03-2017 дата публикации

Instrument and Method for Detecting Analytes

Номер: US20170082543A1
Автор: Alan Furlan
Принадлежит: Roche Molecular Systems Inc

The present disclosure provides an instrument and methods for detecting an analyte, comprising a light source capable of generating excitation light for exciting a plurality of luminescence labels, an excitation beam path extending between said light source and said analyte, a detector capable of detecting light emitted from said luminescence label, an emission beam path extending between said analyte and said detector, a filter carrier carrying two or more pairs of filter portions, each pair being related to one luminescence label and comprising a first filter portion for transmitting excitation light and a second filter portion for transmitting emitted light, wherein said first filter portion of one pair is said second filter portion of another pair, and wherein said filter portions are arranged in a manner that a respective one of said pairs can be brought in an operative condition in which said first filter portion is in said excitation beam path and said second filter portion is in said emission beam path, and wherein said filter carrier and said beam paths are movable with respect to each other by at least one moving mechanism so as to bring a respective one of said pairs in said operative condition.

Подробнее
Номер записи: 61
25-03-2021 дата публикации

Methods and devices for detecting intensity of light with translucent detector

Номер: US20210085228A1
Автор: Cristiano Dalvi, Ferdyan Lesmana, Hung Vo, Jeroen Poeze, Jesse Chen, Kevin PAULEY, Sean Merritt
Принадлежит: Cercacor Laboratories Inc

An optical measurement device includes a light source, a first detector, and a second detector. The light source emits light to a measurement site of a patient and one or more detectors detect the light from the light source. At least a portion of a detector is translucent and the light passes through the translucent portion prior to reaching the measurement site. A detector receives the light after attenuation and/or reflection or refraction by the measurement site. A processor determines a light intensity of the light source, a light intensity through a tissue site, or a light intensity of reflected or refracted light based on light detected by the one or more detectors. The processor can estimate a concentration of an analyte at the measurement site or an absorption or reflection at the measurement site.

Подробнее
Номер записи: 62
31-03-2022 дата публикации

DEFORMULATION TECHNIQUES FOR DEDUCING THE COMPOSITION OF A MATERIAL FROM A SPECTROGRAM

Номер: US20220099566A1
Автор: Banatao Diosdado Rey, Goncharuk Artem, Keh Lance Co Ting, Murphy Gearoid, Sanjeev Sujit
Принадлежит:

The present disclosure relates to techniques for deformulating the spectra of arbitrary compound formulations such as polymer formulations into their chemical components. Particularly, aspects of the present disclosure are directed to obtaining an initial set of spectra for a plurality of samples comprising pure samples and composite samples, constructing a basis set of spectra for a plurality of pure samples based on the initial set of spectra, and providing or outputting the basis set of spectrum. The basis set of spectra is constructed in an iterative process that attempts to decompose, using a decomposition algorithm or model, the spectrum from the initial set of spectra in order to differentiate the pure samples from the composite samples. The basis set of spectra may then be used to deduce the composition of a material from a spectrogram. 1. A computer-implemented method comprising:obtaining an initial set of spectra for a plurality of samples comprising pure samples and composite samples;{'claim-text': ['(i) selecting a spectrum from the initial set of spectra;', '(ii) attempting to decompose, using a decomposition algorithm or model, the selected spectrum based on spectrum within the basis set of spectra,', '(iii) when the selected spectrum is unable to be decomposed, adding the selected spectrum to the basis set of spectra; and', '(iv) in response to adding the selected spectrum to the basis set of spectra, performing an exclusion search of the basis set of spectra that includes iteratively removing each spectrum from the basis set of spectra, attempting to decompose, using the decomposition algorithm or model, each removed spectrum based on spectrum remaining within the basis set of spectra, and when a removed spectrum is able to be decomposed, identifying the removed spectrum as a composite sample and leaving the removed spectrum out of the basis set of spectra, or when the removed spectrum is unable to be decomposed, identifying the removed spectrum as a ...

Подробнее
Номер записи: 63
31-03-2022 дата публикации

APPARATUS FOR MEASURING RAMAN SCATTERING, AND APPARATUS AND METHOD FOR DETERMINING TRUE FIRE USING THE APPARATUS

Номер: US20220099579A1
Автор: Han Kyu Won, Kim Hyun Seok, KIM Soo Cheol, LEE Kang Bok, MO Sang Hyun, PARK So Young, YANG Hoe Sung
Принадлежит:

Provided is a Raman scattering measurement apparatus including a light source which emits light to smoke particles, a filter configured to block light which is incident to the smoke particles and passes through the particle and to allow Raman scattered light to pass therethrough, and a photodetector which detects the Raman scattered light passing through the filter in order to distinguish fire smoke generated due to a true fire from non-fire smoke generated due to daily life or industrial activity. The present invention also provides a fire determination apparatus including a unit which reads a Raman shift from Raman scattered light detected by the photodetector of the Raman scattering measurement apparatus, estimates a smoke component from the read Raman shift, and determines fire/non-fire from the estimated smoke component and a method thereof. 1. A Raman scattering measurement apparatus comprising:a light source which emits light to smoke particles;a filter configured to block light which is incident to the smoke particles and passes through the particles, and to allow Raman scattered light to pass therethrough; anda photodetector which detects the Raman scattered light passing through the filter.2. The Raman scattering measurement apparatus of claim 1 , wherein the light source includes a laser light source.3. The Raman scattering measurement apparatus of claim 1 , wherein the light source is configured to emit light having at least one wavelength.4. The Raman scattering measurement apparatus of claim 1 , wherein the filter includes an optical filter.5. The Raman scattering measurement apparatus of claim 1 , further comprising a nanoimprint filter which secondarily filters the Raman scattered light passing through the filter and sends the Raman scattered light to the photodetector.6. A fire determination apparatus comprising:a light source which emits light to smoke;a filter configured to block light which is emitted and passes through smoke particles, and allow ...

Подробнее
Номер записи: 64
31-03-2022 дата публикации

DETERMINING ONE OR MORE PARAMETERS OF ONE OR MORE MOLECULES WITHIN A URINE SAMPLE

Номер: US20220099660A1
Автор: Goldman Guy, MELAMED Ofer, OIKNINE Yaniv
Принадлежит: OLIVE DIAGNOSTICS LTD.

A method for determining one or more parameters of one or more molecules within a urine sample, the method includes obtaining signals indicative of absorbance values of the urine sample at multiple frequencies; wherein the multiple frequencies comprise a first water absorbance frequency, second frequencies and a second water absorbance frequency; wherein (a) an absorbance of water to radiation of the first water absorbance frequency, and (b) an absorbance of water to radiation of the first water absorbance frequency is known; calculating normalized absorbance values by normalizing the absorbance values of at least some of the second frequencies based on (a) the absorbance of water to radiation of the first water absorbance frequency and (b) the absorbance of water to radiation of the first water absorbance frequency; and determining the one or more parameters of the one or more molecules within the urine sample based on the normalized absorbance values. 1. A method for determining one or more parameters of one or more molecules within a urine sample , the method comprises:obtaining signals indicative of absorbance values of the urine sample at multiple frequencies; wherein the multiple frequencies comprise a first water absorbance frequency, second frequencies and a second water absorbance frequency; wherein (a) an absorbance of water to radiation of the first water absorbance frequency, and (b) an absorbance of water to radiation of the first water absorbance frequency is known;calculating normalized absorbance values by normalizing the absorbance values of at least some of the second frequencies based on (a) the absorbance of water to radiation of the first water absorbance frequency and (b) the absorbance of water to radiation of the first water absorbance frequency; anddetermining the one or more parameters of the one or more molecules within the urine sample based on the normalized absorbance values.2. The method according to claim 1 , wherein the one or more ...

Подробнее
Номер записи: 65
12-03-2020 дата публикации

SIMULTANEOUS MEASUREMENT OF MULTIPLE ANALYTES OF A LIQUID ASSAY

Номер: US20200080994A1
Автор: Brunelle Jacques
Принадлежит: SIEMENS HEALTHCARE DIAGNOSTICS INC.

Analyzers and methods for making and using analyzers are described such as a method in which multiple absorption readings of a liquid assay are obtained by a photodetector using multiple light sources having at least three separate and independent wavelength ranges and with each of the absorption readings taken at a separate instant of time. Using at least one processor and calibration information of the liquid assay, an amount of at least two analytes within the liquid assay using the multiple absorption readings is determined. 1. An analyzer , comprising:a housing surrounding a test cartridge space sized and configured to receive a test cartridge containing a liquid test sample—reagent mixture configured to undergo an immunotype reaction;a first light source generating a first beam of light passing through the test cartridge space, the first beam of light having a first wavelength range;a second light source generating a second beam of light passing through the test cartridge space, the second beam of light having a second wavelength range different from the first wavelength range;a third light source generating a third beam of light passing through the test cartridge space, the third beam of light having a third wavelength range different from the first and second wavelength range;at least one sample detector positioned to receive one or more of the first, second and third beams of light subsequent to the first, second and third beams of light passing through the test cartridge space to generate first, second and third signals; anda computer system having a processor configured to:receive the first, second, and third signal indicative of light captured by the sample detector at first, second and third instants of time from the first, second and third light sources and to use the first, second, and third signals with calibration data to determine an amount of at least two analytes of interest simultaneously within the liquid test sample-reagent mixture.2. The ...

Подробнее
Номер записи: 66
25-03-2021 дата публикации

Electronic device

Номер: US20210088439A1
Автор: Min Su Cho
Принадлежит: SK hynix Inc

An electronic device includes at least one grid structure that extends in rows and columns of a pixel array including a plurality of imaging pixels and is structured to separate the imaging pixels from one another to provide optical isolation between two adjacent imaging pixels, a grid shutter coupled to the grid structure and configured to allow a gas to enter the grid structure by opening a passage for the gas or block the gas from entering the grid structure by closing the passage in the grid structure, and a gas detection controller configured to identify the gas flowing into the grid structure based on an image that is acquired by the image sensor when the passage for the gas in the grid structure is opened to allow the gas to be present in the grid structure.

Подробнее
Номер записи: 67
21-03-2019 дата публикации

Marker compositions with nitrogen compounds, and methods for making and using same

Номер: US20190085253A1
Автор: Justin J. Frederico, Michael P. Hinton
Принадлежит: United Color Manufacturing Inc

The present disclosure provides compositions, methods, and systems for identifying marked hydrocarbon fluids. These compositions, methods, and systems utilize a gas chromatography marker including a non-pyrrolidinone nitrogen-containing compound. The methods and systems can identify the presence or absence of the gas chromatography marker and/or the non-pyrrolidinone nitrogen-containing compound. The compositions, methods, and systems can optionally utilize a spectroscopic marker.

Подробнее
Номер записи: 68
31-03-2016 дата публикации

Calibration curve creation method and device, target component calibration method and device, and electronic apparatus

Номер: US20160091417A1
Автор: Hikaru KURASAWA, Yoshifumi Arai
Принадлежит: Seiko Epson Corp

A calibration curve creation method includes a step of obtaining an independent component matrix including independent components of each sample, and this step includes a step of obtaining the independent component matrix by performing a first preprocess including normalization of the observation data, a second preprocess including whitening, and independent component analysis in this order. In the first preprocess, normalization is performed after a process based on project on null space (PNS) is performed. In the PNS, as a single-variable function representing a variation which depends on an ordinal number λ (where λ is an integer from 1 to N) of a data length N of the observation data, not a power function of λ with an exponent of an integer but a single-variable function which monotonously increases according to an increase in λ in a range of the value of λ from 1 to N is used.

Подробнее
Номер записи: 69
29-03-2018 дата публикации

Infrared Spectroscopic Reflectometer For Measurement Of High Aspect Ratio Structures

Номер: US20180088040A1
Автор: Krishnan Shankar, Wang David Y.
Принадлежит:

Methods and systems for performing spectroscopic reflectometry measurements of semiconductor structures at infrared wavelengths are presented herein. In some embodiments measurement wavelengths spanning a range from 750 nanometers to 2,600 nanometers, or greater, are employed. In one aspect, reflectometry measurements are performed at oblique angles to reduce the influence of backside reflections on measurement results. In another aspect, a broad range of infrared wavelengths are detected by a detector that includes multiple photosensitive areas having different sensitivity characteristics. Collected light is linearly dispersed across the surface of the detector according to wavelength. Each different photosensitive area is arranged on the detector to sense a different range of incident wavelengths. In this manner, a broad range of wavelengths are detected with high signal to noise ratio by a single detector. 1. A metrology system comprising: one or more illumination sources configured to generate an amount of broadband illumination light including wavelengths spanning a range from 750 nanometers to 2,600 nanometers;', 'an illumination optics subsystem configured to direct the amount of illumination light from the illumination source to a measurement spot on a surface of a specimen under measurement at one or more angles of incidence, one or more azimuth angles, or a combination thereof;', 'a collection optics subsystem configured to collect an amount of collected light from the measurement spot on the surface of the specimen;', 'at least one detector having a planar, two-dimensional surface sensitive to incident light, wherein the at least one detector includes two or more different surface areas each having different photosensitivity, wherein the two or more different surface areas are aligned with a direction of wavelength dispersion across the surface of the at least one detector, the at least one detector configured to detect the incident light and generate ...

Подробнее
Номер записи: 70
05-05-2022 дата публикации

SCROLLING SPECTRAL FILTER

Номер: US20220141428A1
Автор: HOUCK William D., HRUSKA Curtis R.
Принадлежит:

A device including an array of pixels and a filter wheel may capture a plurality of images by exposing the array of pixels. The device may spin, while capturing the plurality of images, the filter wheel, and the filter wheel may include filter segments. In some implementations, a portion of the filter wheel in front of the array of pixels includes two or more filter segments.

Подробнее
Номер записи: 71
19-03-2020 дата публикации

Measurement of bilirubin concentration in blood samples

Номер: US20200088744A1
Автор: Hamed Golmohammadi Ghane, Raziyeh Sadat Tabatabaee, Seyyed Hamid Ahmadi
Принадлежит: Chemistry & Chemical Engineering Research Center Of Iran Ccerci

A method for measuring bilirubin concentration in a sample includes preparing a sensing element, where the sensing element may include a plurality of carbon dots, adding the sample to the sensing element, where the sample may include a plurality of bilirubin molecules, obtaining a first grayscale image of the sensing element under ultra-violate (UV) irradiation, irradiating visible light with a wavelength between 470 nm and 490 nm on the sensing element, obtaining a second grayscale image of the sensing element under ultra-violate (UV) irradiation, calculating a light intensity difference by calculating a difference between a first average light intensity of the first grayscale image and a second average light intensity of the second image, and determining the bilirubin concentration based on a correlation between the bilirubin concentration and the light intensity difference.

Подробнее
Номер записи: 72
09-04-2015 дата публикации

METHOD AND SYSTEM FOR USE IN MONITORING BIOLOGICAL MATERIAL

Номер: US20150099274A1
Автор: Axelrod Noel, Nuttman David, Shimoni Moria
Принадлежит:

An optical system for determining the concentration of a metabolic gas in a container sealed to biological contamination and enclosing a biological material. The optical system has a broadly tunable coherent infrared light source, a detection module, and a control system connected to the light source and detection module and operates the light source, to receive and analyze the data provided by said detection module, and to process the data indicative of the concentration of said metabolic gas in said sealed container. 1. An optical system for determining the concentration of a metabolic gas in a container sealed to biological contamination and enclosing a biological material , comprising:(i) a broadly tunable coherent infrared light source adapted to emit (a) a first substantially monochromatic infrared light beam with wavelengths overlapping with an absorption peak of said metabolic gas; and (b) a second substantially monochromatic infrared light beam with wavelengths overlapping with a transmission peak of said metabolic gas or being outside the absorption spectrum of said metabolic gas;(ii) a detection module configured tor detecting said first and said second substantially monochromatic infrared light beams following their passage through a region of interest being part of said sealed container or in fluid communication with it, wherein said region of interest is free of said biological material; and further configured for generating data indicative of transmission of said region of interest to said first and said second substantially monochromatic infrared light beams; and(iii) a control system connectable to said light source and said detection module and suitable to operate said light source, to receive and analyze the data provided by said detection module, and to process the data indicative of the concentration of said metabolic gas in said sealed container.2. The optical system of claim 1 , wherein said broadly tunable coherent infrared light source has a ...

Подробнее
Номер записи: 73
01-04-2021 дата публикации

Apparatus and Method for Measuring the Light Absorbance of a Substance in a Solution

Номер: US20210096059A1
Автор: EHRING HANNO
Принадлежит:

The present invention relates to an apparatus for measuring the absorbance of a substance in a solution, comprising at least one sample cell arranged to contain said solution that is at least partially transparent to light of a predefined wavelength spectrum, at least two light passages through said at least one sample cell, each of said light passages having a known path length, an LED light source arrangement comprising at least two LEDs, each arranged to emit a light output with a wavelength within said predefined wavelength spectrum, wherein a plurality of optical fibers, one for each light passage, is arranged at each LED for receiving said light output and guiding it to the light passages. The invention also relates to a method for measuring the absorbance of a substance in a solution. 2. Apparatus according to claim 1 , further comprising a controller arranged to control the light output from the LED light source arrangement.3. Apparatus according to claim 1 , wherein said at least one flow cell is a dual path length flow cell comprising said at least two light passages claim 1 , and wherein each of said light passages has a path length differing from each of the other light passages.4. Apparatus according to claim 1 , further comprising at least two flow cells claim 1 , each having at least one light passage.5. Apparatus according to claim 1 , wherein the LED light source arrangement further comprises at least one optical filter for each LED claim 1 , said optical filter being arranged between the LED and the optical fiber bundle.6. Apparatus according to claim 1 , further comprising at least two optical filters for each LED of the LED light source arrangement claim 1 , said optical filters being arranged between an output end of each optical fiber and an entrance of a corresponding light passage.7. Apparatus according to claim 1 , further comprising at least two optical filters for each LED of the LED light source arrangement claim 1 , said optical filters ...

Подробнее
Номер записи: 74
05-04-2018 дата публикации

Photoacoustic Chemical Detector

Номер: US20180095026A1
Автор: Prasad Narasimha S.
Принадлежит:

A laser vibrometer for measurement of ambient chemical species includes a laser that produces a beam that is split into a reference readout beam and a signal readout beam. A probe laser beam is tuned to an absorption feature of a molecular transition, and generates acoustic signals when incident on a gaseous species via the photo acoustic effect. The scattered acoustic signals are incident on a thin membrane that vibrates. The readout laser beam reflected from the vibrating membrane is mixed with the reference beam at the surface of a photo-EMF detector. Interferrometric fringes are generated at the surface of the photo-EMF detector. Electric current is generated in the photo-EMF detector when the fringes are in motion due to undulations in the signal readout beam imparted by the vibrating membrane. A highly sensitive photo-EMF detector is capable of detecting picoJoules or less laser energy generated by vibrating processes. 111-. (canceled)12. A laser vibrometer capable of detecting chemical species , comprising: an external probe beam, having a wavelength corresponding to an absorption feature of the chemical species to be detected;', 'a reference beam; and', 'a sensing beam,, 'a light source configured to produce a beams of monochromatic light includinga pressure-sensing diaphragm which when impacted by the pressure waves resulting from the external probe beam interacting with a chemical species that is located away from the sensing beam responsively vibrates;a photo-electromotive force (photo-EMF) sensor;wherein the sensing beam is directed against the second side of the pressure sensing diaphragm; andwherein the sensing beam is directed to the photo-EMF sensor from the pressure-sensing diaphragm which photo-EMF sensor outputs a signal corresponding to the displacement of the diaphragm caused by the incident pressure wave.13. The laser vibrometer of claim 12 , wherein the light source includes:a laser configured to produce a beam of monochromatic light having a ...

Подробнее
Номер записи: 75
05-04-2018 дата публикации

N2O ANALYSIS DEVICE AND ANALYSIS METHOD

Номер: US20180095030A1
Автор: FUJII Shuuji, Muta Kenji, NISHIMIYA Tatsuyuki, TADANAGA Osamu, TOKURA Akio, TSUMURA Yoichiro
Принадлежит:

This NO analysis device is provided with: a light source () which radiates laser light onto an exhaust gas () containing NO, HO and CO; a light receiver () which receives the laser light that has been radiated onto the exhaust gas (); a light source control unit () of a control device (), which controls the wavelength of the laser light radiated by the light source () to between 3.84 μm and 4.00 μm; and a signal analyzing unit () of the control device (), which calculates the NO concentration by means of infrared spectroscopy, using the laser light received by the light receiver () and the laser light controlled by the light source control unit () of the control device (). 1. An NO analysis device comprising:{'sub': 2', '2', '2, 'light emission means for emitting laser light to flue gas containing NO, HO, and CO;'}light reception means for receiving the laser light emitted to the flue gas;wavelength control means for performing control such that a wavelength of the laser light emitted by the light emission means is in a 3.84 to 4.00 μm band; and{'sub': 2', '2, 'NO concentration calculation means for calculating a concentration of NO by means of infrared spectroscopy, using the laser light received by the light reception means and the laser light controlled by the wavelength control means.'}2. The NO analysis device according to claim 1 , whereinthe wavelength control means performs control such that the wavelength of the laser light is 3.9034 to 3.9060 μm, 3.9090 to 3.9116 μm, or 3.9122 to 3.9148 μm.3. The NO analysis device according to claim 1 , whereinthe wavelength control means performs control such that the wavelength of the laser light is 3.9047 μm, 3.9103 μm, or 3.9135 μm.4. The NO analysis device according to claim 1 , wherein{'sub': 1', '2', '3', '3', '1', '2', '3, 'the light emission means includes a nonlinear optical crystal, generates, by means of difference frequency generation using inputs of laser light with a wavelength of λand laser light with a ...

Подробнее
Номер записи: 76
28-03-2019 дата публикации

Hydrogen sensitive films and sensors produced therefrom

Номер: US20190094147A1
Автор: Daniel P. Rose, Daoli Zhao, John A. Lynch, Julia Kuhlmann, Michael E. Smith, Peng Zhang, William R. Heineman
Принадлежит: University of Cincinnati

Described are sensors and methods of detecting hydrogen gas. The sensor includes a polymer matrix and a dye molecule in an amount sufficient such that exposure of the polymer matrix to hydrogen gas causes a change in a spectroscopic property of the dye molecule wherein the spectroscopic property includes at least one of color, absorbance, or luminescence. The polymer matrix may further include a catalyst, such as a transition metal, sulfonated Wilkinson's catalyst, colloidal Pt, sulfonated iridium cyclooctadiene triphenylphosphine, sulfonated rhodium cyclooctadiene triphenylphosphine, sulfonated ruthenium triphenylphosphine, or combinations thereof. Embodiments of the sensor may further include a gas permeable, water impermeable membrane, an outer covering, or combinations thereof.

Подробнее
Номер записи: 77
06-04-2017 дата публикации

OPTICAL SENSOR FOR FLUID ANALYSIS

Номер: US20170097329A1
Автор: Boardman Edward Andrew, MORI JUN, Smeeton Tim Michael
Принадлежит:

A sensor for measuring a concentration of a particular ion, molecule or atom in a fluid includes a sample handling portion for providing at least some of the fluid, a first photo-detection device, and a first light source. The first photo-detection device is configured to measure a power of light incident thereon, and the first light source includes a solid-state light emitting device. The first light source is configured to emit light having a wavelength less than 240 nanometers incident on the fluid provided by the sample handling portion, and the first photo-detection device is configured to receive light having passed through the fluid. 1. A sensor for measuring a concentration of one or more types of ions , molecules or atoms in a fluid , comprising:at least one photo-detection device configured to measure a power of light incident thereon;a first light source including a solid-state light emitting device, the first light source configured to emit light having a wavelength less than 240 nanometers incident on the fluid, and the at least one photo-detection device configured to receive light having passed through the fluid; anda second light source including a solid-state light emitting device, the second light source configured to emit light having a wavelength less than 240 nanometers, different from the wavelength emitted by the first light source, incident on the fluid, the at least one photo-detection device configured to receive light having passed through the fluid.2. The sensor according to claim 1 , where the at least one photo-detection device comprises a first photo-detection device and a second photo-detection device claim 1 , and wherein the first photo-detection device is configured to receive light from the first light source having passed through the fluid claim 1 , and the second photo-detection device is configured to receive light from the second light source having passed through the fluid.3. The sensor according to claim 1 , wherein a ...

Подробнее
Номер записи: 78
23-04-2015 дата публикации

Apparatus, composition and method for determination of chemical oxidation demand

Номер: US20150108009A1
Автор: John Lee, Richard E. Leggett, Vishnu V. Rajasekharan
Принадлежит: Hach Co

Methods for measuring chemical oxygen demand, a composition and a kit useful for measuring chemical oxygen demand, a method for calibrating a chemical oxygen demand analysis method, and a method for determining carbonaceous chemical oxygen demand are disclosed.

Подробнее
Номер записи: 79
02-06-2022 дата публикации

MEASURING DEVICE FOR MEASURING THE ABSORPTION OF GASES

Номер: US20220170851A1
Автор: TRÖLLSCH Arne
Принадлежит:

A measuring device is provided for measuring the absorption of gases. The measuring device () includes a radiation source (), a first detector element (), a second detector element () and a reflector array (). The reflector array () defines a first optical path () between the radiation source () and the first detector element () and defines a second optical path () between the radiation source () and the second detector element (). The first optical path () has at least two points of intersection with itself and the second detector element () is arranged outside of a first plane which is defined by the radiation source () and two points of intersection () of the first optical path (). 1. A measuring device for measuring the absorption of gases , the measuring device comprising:a radiation source;a first detector element;a second detector element; anda reflector array, the reflector array defining a first optical path between the radiation source and the first detector element and the reflector array defining a second optical path between the radiation source and the second detector element, the first optical path and the second optical path being located in different planes, wherein the first optical path has at least two points of intersection with itself, the second detector element being arranged outside of one of the planes that is defined by the radiation source and the at least two points of intersection of the first optical path, the radiation source being configured to emit at least a beam of radiation along the first optical path such the beam of radiation intersects itself at least twice, wherein the second optical path has no point of intersection with itself.2. A measuring device in accordance with claim 1 , wherein the first optical path has at least three points of intersection with itself in only one of the planes.3. A measuring device in accordance with claim 1 , further comprising a wall element enclosing a measuring chamber claim 1 , wherein the ...

Подробнее
Номер записи: 80
02-06-2022 дата публикации

ADJUSTABLE ELECTRONIC WAVELENGTH BAND PASS SENSOR FOR SOFT X-RAY THROUGH IR SPECTRAL BANDS

Номер: US20220170853A1
Автор: Fricke William C., Ganopoulos Mike, Martin Clifford A., Wilson John K.
Принадлежит:

Exemplary aspects of the present invention are directed to a sensor that uses the spectral sensitivity of detectors, the spectral properties of optical filters, and mathematical addition and or subtraction to isolate the desired spectral band. The sensor includes a downconverter member for converting the high energy beam to easily detectable visible or NIR light, and optical filter elements and relay optics for directing the visible light to the sensing members. The sensing members transmit an electronic signal proportional to the power of the light in the passband to amplifiers wherein multiple sensing members convey optical power of selected wavelength bands through an amplifier to a microprocessor with an algorithm to determine the power in the desired band of interest and then to a displaying member. The system may be used in a vacuum, in ambient non-vacuum conditions or a purged environment. The techniques described herein can be used across the X-ray, UV, visible, near IR, IR and other electromagnetic regions to isolate desired bands. 1. A power sensor for a beam , comprising:a downconverter for converting the beam to visible light;one or more detectors for sensing an power of the visible light thereon;wherein each of the one or more detectors is a band specific detector and in communication with the other band specific detectors for conveying information regarding comparative power of the visible light in multiple channels to the other band specific detectors.2. The power sensor according to claim 1 , wherein the one or more detectors are a silicon detector or other sensor configured to detect the energy in the emission spectrum of the resulting energy from the downconverter.3. The power sensor according to claim 1 , wherein an algorithm is used to separate multiple channels to calculate the desired resulting band(s) of interest.4. The power sensor according to claim 3 , wherein the bands of interest are one or more of UVA claim 3 , UVB claim 3 , UVC bands.5. ...

Подробнее
Номер записи: 81
30-04-2015 дата публикации

METHOD AND APPARATUS FOR SELECTING WAVELENGTHS FOR OPTICAL MEASUREMENTS OF A PROPERTY OF A MOLECULAR ANALYTE

Номер: US20150119661A1
Автор: Delp Gary S., Gilbert Barry K., Haider Clifton R.
Принадлежит: Mayo Foundation for Medical Education and Research

A system and optimization algorithm for determining the preferred operational wavelengths of a device configured for measurement of molecular analytes in a sample. Operational wavelengths are determined by solving a system of equations linking empirically defined functions representative of these analytes, spectrally dependent coefficients corresponding to these analytes, path lengths traversed by waves probing the analytes at wavelengths corresponding to the absorption level described by the functions representative of these analytes, and, optionally, a cost-function taking into account at least one of spectral separation between the operational wavelengths, manufacturability of wave source(s) producing wave(s) at operational wavelength(s), and the noise factor associated with the operation of such wave source(s). 1. A method for determining a regime of operation of a spectrometric device that is cooperated with a sample , enabled to generate electromagnetic waves (EMWs) , and configured to measure a property of a material component of the sample , the method comprising:receiving, at a user-input device, data representing empirically-defined spectrally-dependent characteristic of at least first and second material components of the sample;defining a first system of equations representing the empirically-defined spectrally dependent characteristic as functions of at least respectively corresponding concentrations of the at least first and second material components in the sample and spectrally-dependent paths of EMWs through the sample, the EMWs respectively corresponding to the at least first sand second material components;defining a second system of equations including the first system of equations and additional equations employing at least one parameter representing operational utility of the device; andsolving said second system of equations to determine wavelengths of operation of the device such as to ensure that the figure of merit, representing operational ...

Подробнее
Номер записи: 82
18-04-2019 дата публикации

LIMULUS AMOEBOCYTE LYSATE ASSAY AND METHOD OF SAME

Номер: US20190113514A1
Автор: Scudder Jonathan D., Ye Jing Yong
Принадлежит:

A pyrogenicity test assay and method of pyrogen testing that allows for rapid and ultrahigh sensitivity testing of parenteral pharmaceuticals or medical devices that contact blood or cerebrospinal fluid by employing a Limulus Amoebocyte Lysate (LAL) assay utilizing a photonic-crystal biosensor. The photonic-crystal biosensor is capable of determining the presence of endotoxins in a test sample by monitoring shifts in the resonant wavelength of an open microcavity affected by the changes in the refractive index of the analyte solutions used. 1. A Limulus Amoebocyte Lysate (LAL) assay system comprising means for measuring endotoxins in an analyte by monitoring changes in a refractive index of the analyte.2. The LAL assay system of claim 1 , wherein the means for measuring endotoxins comprise a photonic crystal biosensor.3. The LAL assay system of claim 1 , wherein the means for measuring endotoxins comprise a photonic crystal total internal reflection (PC-TIR) biosensor.4. The LAL assay system of claim 3 , further comprising at least one analyte well associated with the PC-TIR biosensor.5. The LAL assay system of claim 3 , further comprising means for providing polarized light to the PC-TIR biosensor.6. The LAL assay system of claim 4 , further comprising a prism for transmitting light to the PC-TIR biosensor and passing the light from the PC-TIR biosensor to a spectrometer for receiving the transmitted light.7. The LAL assay system of claim 5 , further comprising:a light source having a polarizer optically coupled thereto;a beam splitter optically coupled to the polarizer;a prism optically coupled to at least one of a plurality of analyte wells associated with the PC-TIR biosensor; anda spectrometer optically coupled to the prism.8. The LAL assay system of wherein an optical fiber optically couples the light source to the polarizer.9. The LAL assay system of claim 3 , wherein the PC-TIR biosensor further comprises a plurality of microchannels on a surface thereof.10. ...

Подробнее
Номер записи: 83
03-05-2018 дата публикации

MEDICAL HYPERSPECTRAL IMAGING FOR EVALUATION OF TISSUE AND TUMOR

Номер: US20180116526A1
Автор: Freeman Jenny, Panasyuk Alexander, Panasyuk Svetlana V.
Принадлежит:

Apparatus and methods for hyperspectral imaging analysis that assists in real and near-real time assessment of biological tissue condition, viability, and type, and monitoring the above overtime. Embodiments of the invention are particularly useful in surgery, clinical procedures, tissue assessment, diagnostic procedures, health monitoring, and medical evaluations, especially in the detection and treatment of cancer. 120-. (canceled)21. A method for displaying information about an in vivo tissue in a region of interest of a subject , the method comprising:co-registering corresponding pixels in each image in a plurality of images of the region of interest, each respective image in the plurality of images corresponding to radiation emitted at a particular spectral band in a plurality of different spectral bands;deriving a coefficient for oxyhemoglobin and a coefficient for deoxyhemoglobin from each set of co-registered pixels in the plurality of images;generating, based on the plurality of images, a two-dimensional index characterizing the particular characteristic of the in vivo tissue, wherein the two-dimensional index includes a first scale to represent a concentration of oxyhemoglobin in the in vivo tissue and a second scale to indicate a concentration of deoxyhemoglobin in the in vivo tissue; anddisplaying the coefficient for oxyhemoglobin and the coefficient for deoxyhemoglobin from at least one set of co-registered pixels in the plurality of images independently with the two-dimensional index.22. The method of claim 21 , wherein at least one respective spectral band in the plurality of spectral bands corresponds to radiation emitted in the visible spectrum.23. The method of claim 21 , wherein at least one respective spectral band in the plurality of spectral bands corresponds to radiation emitted in the near-infrared spectrum.24. The method of claim 21 , wherein the coefficient for oxyhemoglobin and the coefficient for deoxyhemoglobin from at least one set of ...

Подробнее
Номер записи: 84
05-05-2016 дата публикации

SYSTEM FOR ANALYZING MERCURY

Номер: US20160123946A1
Автор: Dufresne Philip J.
Принадлежит:

An analyzer system () for measuring the mercury content of samples includes a mercury vapor analyzer () for generating and detecting analytical beams. A furnace () is mounted to a measurement cell (). A sample boat () containing a sample is adapted to be disposed within the furnace to release heated sample effluent gas from the sample into the measurement cell. An optical bench () mounted to the mercury vapor analyzer () into which the measurement cell () is positioned in a path traveled by the analytical beams projected out of the vapor analyzer whereby the analytical beams traverse the measurement cell, interact with the sample effluent gas and return back to the vapor analyzer () where the amount of mercury in the heated sample effluent gas can be determined. A pump station () to draw the sample effluent gas from the measurement cell. 110. An analyzer system () for measuring mercury , comprising:{'b': '12', 'a mercury vapor analyzer () for generating and detecting analytical beams;'}{'b': 24', '22, 'a furnace () mounted to a measurement cell ();'}{'b': '30', 'a sample boat () to contain samples adapted to be disposed within the furnace to release a sample effluent gas from the samples into the measurement cell;'}{'b': 16', '12', '22', '180, 'an optical bench () mounted to the mercury vapor analyzer () into which the measurement cell (,) can be positioned so that the analytical beams can traverse the measurement cell, interact with the sample effluent gas and return to the vapor analyzer where the amount of mercury in the sample effluent gas can be determined; and'}{'b': '56', 'a pump station () to draw the sample effluent gas from the measurement cell.'}21044. The analyzer system () of further including an exhaust gas conditioner () to receive the sample effluent gas from the measurement cell and to cool the sample gas so as to condense any excess moisture carried in the sample gas.31016. The analyzer system () of wherein the optical bench () includes:{'b': 78', ...

Подробнее
Номер записи: 85
25-08-2022 дата публикации

Non-dispersive multi-channel sensor assembly having refractive and/or diffractive beamsplitter

Номер: US20220265945A1
Автор: Bernd Offenbeck, Christoph Schranz, Dominik Novotni
Принадлежит: HAMILTON MEDICAL AG

A non-dispersive multi-channel radiation sensor assembly includes a beamsplitter assembly, a first band-pass filter, which has a predefined first bandwidth and has a transmission maximum at a predefined first useful-signal wavelength, a first measurement-radiation useful-signal sensor, which is arranged downstream of the first band-pass filter in the beam path, a second band-pass filter, which has a transmission maximum at a predefined first reference-signal wavelength, a first measurement-radiation reference-signal sensor, which is arranged downstream of the second band-pass filter in the beam path. The beamsplitter assembly has a first irradiation region and a second irradiation region, in which irradiation regions the beamsplitter assembly is irradiated with measurement radiation. The irradiation regions are optically designed in such a way that the beamsplitter assembly deflects, in the first irradiation region, a first part of the measurement radiation onto the first band-pass filter and a second part of the measurement radiation onto the second band-pass filter.

Подробнее
Номер записи: 86
27-05-2021 дата публикации

Signal augmentation method in spectroscopy device using vapor cell and spectroscopy device using the same

Номер: US20210156794A1
Автор: Dai Hyuk Yu, Han Seb Moon, Hyun Gue HONG, Jae Hoon Lee, Taek Jeong
Принадлежит: Korea Research Institute of Standards and Science KRISS

A method is disclosed for increasing an intensity of a signal detected in a spectroscopy device using a vapor cell and a spectroscopy device using the same. An operation method of the spectroscopy device may include: causing a first light for exciting an atom trapped in a vapor cell in a first hyperfine ground state to a first excited state to be incident on the vapor cell; causing a second light for exciting an atom trapped in the vapor cell in a second hyperfine ground state to a second excited state to be incident on the vapor cell; causing a third light for exciting the atom in the second excited state to a third excited state to be incident on the vapor cell; and detecting fluorescence which is emitted while the atom in the third excited state returns to the ground state.

Подробнее
Номер записи: 87
12-05-2016 дата публикации

Infrared Detection and Imaging Device With No Moving Parts

Номер: US20160131576A1
Автор: Amir Gil, Dario Cabib
Принадлежит: CI Systems Israel Ltd

A device images radiation from a scene. A detector is sensitive to the radiation in a first wavelength band. A lens forms an image of the scene on the detector. A filtering arrangement includes two sets of radiation absorbing molecules. A control unit switches the filtering arrangement between two states. In the first state, all of the radiation in the first wavelength band is transmitted to the detector. In the second state, the radiation in a second wavelength band within the first wavelength band is absorbed by the radiation absorbing molecules. The control unit synchronizes the switching of the filtering arrangement with the detector. Each pixel of the image formed on the detector includes two signals. The first signal includes information from the scene radiation in the first wavelength band. The second signal excludes information from the scene radiation absorbed by the filtering arrangement in the second wavelength band.

Подробнее
Номер записи: 88
02-05-2019 дата публикации

ANALYSIS DEVICE

Номер: US20190125229A1
Автор: Chiba Toru, OBARA Yoshimi
Принадлежит: HOYA CORPORATION

An analysis device includes a wavelength selection unit that alternatively extracts first special light and second special light from light emitted from the light source device, an image sensor that includes a RGB color filter, and a signal processing unit. In this configuration, the first special light includes light in a first wavelength region and the second special light includes light in a second wavelength region that is different from the first wavelength region. The signal processing unit calculates an indicator that indicates a feature amount of biological tissue based on a pixel signal that corresponds to the light in the first wavelength region and a pixel signal that corresponds to the light in the second wavelength region, and generates a color captured image based on a pixel signal that corresponds to light that passes through the RGB color filter. 1. An analysis device comprising:a light source device;a wavelength selection unit that alternatively extracts first special light and second special light from light emitted from the light source device, the first special light and the second special light having mutually different spectrums;an image sensor that includes an RGB color filter, receives light from a biological tissue that is a subject, and outputs a pixel signal that corresponds to the received light; anda signal processing unit that performs predetermined signal processing on the pixel signal output from the image sensor,wherein the first special light includes light in a first wavelength region that passes through a G filter of the RGB color filter,the second special light includes light in a second wavelength region that passes through the G filter, the second wavelength region being different from the first wavelength region,at least one of the first special light and the second special light includes light that passes through an R filter of the RGB color filter,at least one of the first special light and the second special light includes ...

Подробнее
Номер записи: 89
01-09-2022 дата публикации

GAS SENSORS

Номер: US20220276159A1
Автор: GRENNBERG FISMEN Britta, HESTNES BAKKE Kari Anne, JOHANSEN Ib-Rune, SAGBERG Håkon, SANDVEN Knut Baeroe, TSCHUDI Jon
Принадлежит:

A gas sensor for measuring concentration of a predetermined gas includes a light source () arranged to emit pulses of light, a measurement volume (), a detector () arranged to receive light that has passed through the measurement volume (), and an adaptable filter () disposed between the light source () and the detector (). The gas sensor has a measurement state in which it passes at least one wavelength band which is absorbed by the gas and a reference state in which said wavelength band is attenuated relative to the measurement state. A controller is connected to each of the light source, the detector and the adaptable filter to change the adaptable filter between one of said measurement state and said reference state to the other at least once during a gas sensor operation period. 1. A gas sensor for measuring a concentration of a gas , the gas sensor comprising:a light source configured to be switched on to emit light and to be switched off;a measurement volume;a detector configured to receive light that has passed through the measurement volume to output a photo detector signal;an adaptable filter disposed between the light source and the detector and having a measurement state in which the adaptable filter passes at least one wavelength band which is absorbed by the gas and a reference state in which said at least one wavelength band is attenuated relative to the measurement state; anda controller connected to each of the light source, the detector and the adaptable filter, the controller being configured:to switch the adaptable filter between the measurement state and the reference state;to switch on the light source at a start of a gas sensor operation period and to control power to the light source such that the light source emits a pulse of light above a predetermined threshold during said gas sensor operation period; the control of power to the light source during said gas sensor operation period includes initiating an initial powering of the light source ...

Подробнее
Номер записи: 90
01-09-2022 дата публикации

APPARATUS FOR MEASURING MULTI-WAVELENGTH TRANSMITTANCE USING LEARNED LED TEMPERATURE COMPENSATION MODEL

Номер: US20220276162A1
Автор: GLOVER JAMES ANDREW
Принадлежит:

A device to measure the amount of light able to transmit through a liquid. The device uses a light detector and multiple light emitting diodes (LED's) along with an optical unit such that the light detector, LED's, and an optical unit define a path of light emitted by each individual LED or subgroup of LED's and detected by the detector. The device uses a structure designed to surround the LED's and light detector such that the structure allows the device to be immersed in the liquid and such that the structure is shaped to allow a volume of liquid to be between the LED's and detector, intersecting the light path. 1. A submersible apparatus for measuring multiple wavelengths of light transmittance through a liquid , the apparatus comprising:multiple light emitting diodes (LEDs) of different peak output wavelengths;a light detector for detecting an intensity of light;a structure surrounding the LEDs and detector wherein said structure allows the apparatus to be submersed in a liquid wherein the structure is shaped to allow a volume of liquid to be between the LEDs and detector such that the amount of light able to transmit through the liquid from the LEDs is detected by the detector;an optical unit that collects light from the LEDs and directs it though the liquid without the need for moving parts;at least one temperature sensor mounted near the LEDs as well as a temperature sensor mounted near the light detector to record the temperature of the LEDs and detector during transmission measurements;a microprocessor programmed to:a) control the LEDs such that the LEDs can be energized one at a time or in sub-groups of the total number of LEDs, and subsequently measure via the detector the amount of light for a specific LED or sub-group of LEDs able to transmit though the liquid;b) use a predictive model applied to data derived from the temperature sensors light detector to compensate the transmittance measurements for the effects of temperature on raw light output of the ...

Подробнее
Номер записи: 91
03-06-2021 дата публикации

Device for conducting radiation, a photodetector arrangement, and a method for spatially resolved spectral analysis

Номер: US20210164892A1
Автор: Marius Grundmann
Принадлежит: UNIVERSITAET LEIPZIG

The invention relates to a device for conducting radiation, a photodetector arrangement, and a method for spatially resolved spectral analysis.

Подробнее
Номер записи: 92
03-06-2021 дата публикации

GAS SENSORS

Номер: US20210164895A1
Автор: GRENNBERG FISMEN Britta, HESTNES BAKKE Kari Anne, JOHANSEN Ib-Rune, SAGBERG Håkon, SANDVEN Knut Baeroe, TSCHUDI Jon
Принадлежит:

A gas sensor for measuring concentration of a predetermined gas includes a light source () arranged to emit pulses of light, a measurement volume (), a detector () arranged to receive light that has passed through the measurement volume (), and an adaptable filter () disposed between the light source () and the detector (). The gas sensor has a measurement state in which it passes at least one wavelength band which is absorbed by the gas and a reference state in which said wavelength band is attenuated relative to the measurement state. A controller is connected to each of the light source, the detector and the adaptable filter to change the adaptable filter between one of said measurement state and said reference state to the other at least once during a gas sensor operation period. 1. A gas sensor for measuring a concentration of a gas , the gas sensor comprising:a light source configured to be switched on to emit light and to be switched off;a measurement volume;a detector configured to receive light that has passed through the measurement volume to output a photo detector signal;an adaptable filter disposed between the light source and the detector and having a measurement state in which the adaptable filter passes at least one wavelength band which is absorbed by the gas and a reference state in which said wavelength band is attenuated relative to the measurement state; anda controller connected to each of the light source, the detector and the adaptable filter, the controller being configured:to switch the adaptable filter between the measurement state and the reference state;to switch on the light source at a start of a gas sensor operation period and to control power to the light source during said gas sensor operation period; the control of power to the light source during said gas sensor operation period includes initiating an initial powering of the light source during a pre-heat stage of the gas sensor operation period to preheat the light source to a ...

Подробнее
Номер записи: 93
03-06-2021 дата публикации

DEVICE AND METHOD FOR DETERMINING A WAVELENGTH OF A RADIATION

Номер: US20210164901A1
Автор: GRUNDMANN Marius
Принадлежит: Universität Leipzig

The invention relates to a device and a method for determining a wavelength of radiation. 1101214121416. A device () for determining a wavelength of radiation comprising at least two absorption elements ( , ) for generating photosignals , wherein the absorption elements ( , ) are arranged in a layer structure () one above the other ,characterized in that{'b': 12', '14, 'an upper absorption element () has a vertically varying chemical composition, which is characterized by a material gradient in order to set a wavelength-dependent absorption coefficient, and a lower absorption element () is designed to be chemically homogeneous.'}210. The device () according to claim 1 ,characterized in that{'b': 12', '14, 'the absorption elements (, ) comprise at least one semiconductor material.'}310. The device () according to or claim 1 ,characterized in that{'b': 12', '14, 'the absorption elements (, ) comprise binary, ternary, or quaternary alloys of semiconductors, preferably direct semiconductors.'}410. The device () according to any one or more of the preceding claims claim 1 ,characterized in that{'b': '12', 'the material gradient is varied monotonically rising or falling vertically, wherein the material gradient preferably has a linear or quadratic dependence on the vertical position within the upper absorption element ().'}510. The device () according to any one or more of the preceding claims claim 1 ,characterized in that{'b': '12', 'the material gradient in the upper absorption element () is formed by a vertical variation of the proportions of the alloy partners of a semiconductor alloy.'}610. The device () according to any one or more of the preceding claims claim 1 ,characterized in that{'b': '12', 'sub': x', '1-X, 'the upper absorption element () comprises a semiconductor alloy of the general form AB, wherein A and B each characterize alloy partners and x is the proportion of A in the semiconductor alloy which is vertically varied.'}710. The device () according to ...

Подробнее
Номер записи: 94
23-04-2020 дата публикации

Controlling plant detection systems using phase delay analysis

Номер: US20200128639A1
Автор: Aubrey Jason Calder, James G. Quaderer, XIN ZHAO
Принадлежит: Trimble Inc

Methods for controlling a plant detection system include determining a target phase delay based on a first phase delay of reflected portions of a first light beam and a second phase delay of reflected portions of a second light beam. A composite light beam comprising the first light beam and the second light beam is emitter towards bare soil, and reflected portions of the composite light beam are detected. An intensity of at least one of the first light beam or the second light beam is adjusted so that a phase delay of the composite light beam is approximately equal to the target phase delay.

Подробнее
Номер записи: 95
30-04-2020 дата публикации

METHODS AND DEVICES FOR DETECTING MERCURY ISOTOPES IN CRUDE OIL

Номер: US20200132659A1
Автор: TANG Shunlin, ZHU Guangyou
Принадлежит: PETROCHINA COMPANY LIMITED

The present disclosure relates to a method and device for detecting mercury isotopes in crude oil. The device comprises an enrichment-absorption system and a secondary purification-enrichment system for mercury isotopes, wherein the enrichment-absorption system includes an air-background mercury absorption system, a pyrolysis/cracking system, a mercury-sample absorption system connected in series with pipe lines, and a vacuum pump, and the vacuum pump is connected to the mercury-sample absorption system through a pipe line; the secondary purification-enrichment system includes a nitrogen-gas cylinder, a collection bottle with potassium permanganate absorption liquid, and a secondary enrichment-absorption bottle connected in series with pipe lines, wherein the secondary purification-enrichment system further includes a stannous-chloride storage bottle, which is connected to a pipe line between the nitrogen-gas cylinder and the collection bottle with potassium-permanganate absorption liquid via a peristaltic pump and through a pipe line. 1. A device for detecting mercury isotopes in crude oil , which comprises an enrichment-absorption system and a secondary purification-enrichment system for mercury isotopes , wherein the enrichment-absorption system comprises an air-background mercury absorption system , a pyrolysis/cracking system , and a mercury-sample absorption system connected in series with pipe lines , and a vacuum pump , wherein the vacuum pump is connected to the mercury-sample absorption system through a pipe line; andthe secondary purification-enrichment system comprises a nitrogen-gas cylinder, a collection bottle with potassium-permanganate absorption liquid, and a secondary enrichment-absorption bottle connected in series with pipe lines, wherein the secondary purification-enrichment system further comprises a stannous-chloride storage bottle, which is connected to a pipe line between the nitrogen-gas cylinder and the collection bottle with potassium- ...

Подробнее
Номер записи: 96
10-06-2021 дата публикации

SHORT PULSEWIDTH REPETITION RATE NANOSECOND TRANSIENT ABSORPTION SPECTROMETER

Номер: US20210172799A1
Автор: Asbury John B., Grieco Christopher, Kennehan Eric, Rimshaw Adam
Принадлежит:

A high-sensitivity nanosecond to millisecond transient absorption spectrometer for measurements of miniscule signals under low excitation intensities includes an excitation source generating a frequency greater than 100 Hz, pulsewidth less than 5 ns excitation pulse for exciting a light absorbing sample, a probe light source for generating a photon flux probe light beam producing an average irradiance greater than 1 μW mnmfor measuring the transient absorption spectrum of the sample before and after excitation by the excitation source, a DC-coupled detector capable of measuring light for enabling synchronous measurement of both the transmission of the probe light beam and the change in transmission of the probe light beam between a signal with the excitation pulse present and a signal in the absence of the excitation pulse, and a digital oscilloscope with a trigger rearm time capable of collecting every trigger event at high frequencies including 1 MHz, for enabling sequential noise subtraction protocols. 1. A high-sensitivity nanosecond to millisecond transient absorption spectrometer for measurements of miniscule signals under low excitation intensities , comprising:an excitation source generating an excitation pulse for exciting a light absorbing sample;a probe light source generating a probe light beam for measuring a transient absorption spectrum of the sample by monitoring transmission signals of the probe light beam before and after excitation by the excitation pulses;a detector for detecting the transmission signals and a change in the transmission signals of the probe light beam; anda digital oscilloscope for collecting the detected signals; the excitation pulse has a frequency greater than 100 Hz and a pulsewidth less than 5 ns;', {'sup': −2', '−1, 'the probe light beam has a photon flux producing an average irradiance greater than 1 μW mnm'}, 'the detector is a DC-coupled detector operable to measure light for enabling sequential switching of an AC- and ...

Подробнее
Номер записи: 97
10-06-2021 дата публикации

APPARATUS AND METHOD FOR BIOMOLECULAR ANALYSIS

Номер: US20210172863A1
Автор: Marn Allison Marie, ÜNLÜ M. Selim, YURDAKUL CELALETTIN
Принадлежит: TRUSTEES OF BOSTON UNIVERSITY

An apparatus, and method of operating the same, detects changes in biomass accumulating on a surface of a substrate while minimizing bulk effect. The apparatus includes a sensor substrate and two illumination sources. A first illumination source generates a first light having a first central wavelength. A second illumination source generates a second light having a second central wavelength different than the first wavelength. The first and second light are mixed to produce a combined light. An analyte solution is introduced to the sensor substrate. Incident light of the combined light is reflected from the sensor substrate to produce a signal. The signal is imaged with a camera to obtain a reflectance. Reflectance produced by the combined light is not affected by variations in the dielectric properties of the analyte solution. A biomass accumulated on the substrate is computed based on the reflectance. 1. A label-free method of detecting changes in biomass accumulating on a surface , the method comprising:providing a sensor substrate;providing a first illumination source and a second illumination source, the first illumination source generating a first light having a first central wavelength and the second illumination source generating a second light having a second central wavelength, the second central wavelength different than the first central wavelength;mixing the first light with the second light to produce a combined light;providing an analyte solution on the sensor substrate;reflecting incident light of the combined light from the sensor substrate to produce a signal;recording the signal with a camera to obtain a reflectance image; andcomputing a biomass accumulated on the substrate based on the reflectance image.2. The method of claim 1 , further comprising claim 1 , prior to mixing the first light with the second light claim 1 , determining a bulk effect minimization wavelength based on a thickness and a composition of the sensor substrate and a ...

Подробнее
Номер записи: 98
10-06-2021 дата публикации

METHODS OF ASSESSING ANTIBODY-DRUG CONJUGATES

Номер: US20210172866A1
Автор: KULYBA Natallia, SKINNER Andria
Принадлежит:

The present disclosure provides methods of assessing DAR of ADC products that provide advantages over known methods. Specifically, methods of the disclosure can be used in high-throughput applications and/or without having to dilute ADC samples during the assessment. 1. A method of determining a ratio of drug to antibody (DAR) in a sample comprising an antibody-drug conjugate , comprising:placing the sample in a vessel;contacting a probe with the bottom of the vessel;moving the probe from the bottom of the vessel through the sample by a predetermined increment such that a preselected path length through the solution is obtained;detecting absorbance of the sample at a first light wavelength (λ1), wherein the first wavelength is a predetermined absorbance maxima of the antibody;repeating steps of moving the probe relative to the sample and taking a measurement at the first wavelength;generating a regression line from the absorbance at the first wavelength and path length such that a slope of the regression line is obtained;determining the concentration of the antibody by dividing the slope of the regression line by an extinction coefficient of the antibody at the first wavelength;detecting absorbance of the sample at a second light wavelength (λ2), wherein the second wavelength is a predetermined absorbance maxima of the drug;repeating steps of moving the probe relative to the sample and taking a measurement at the second wavelength;generating a regression line from the absorbance at the second wavelength and path length such that a slope of the regression line is obtained;determining the concentration of the drug by dividing the slope of the regression line by an extinction coefficient of the drug at the second wavelength; andcalculating a DAR using the determined concentration of drug and the determined concentration of antibody.2. The method of claim 1 , wherein the size exclusion chromatography comprises ultra-performance liquid chromatography (UPLC) claim 1 , a ...

Подробнее
Номер записи: 99
10-06-2021 дата публикации

Apparatus and method for estimating bio-information

Номер: US20210172867A1
Автор: Hyeong Seok Jang, Jin Young Park, Kun Sun Eom, Sung Mo Ahn
Принадлежит: SAMSUNG ELECTRONICS CO LTD

An apparatus for estimating bio-information includes an optical sensor including a light source configured to emit light of multiple wavelengths onto an object, and including a plurality of detectors configured to detect light of each wavelength which is scattered or reflected from the object. The apparatus includes a processor configured to obtain spectra based on light of each wavelength which is detected by each detector, determine valid spectra of the obtained spectra, and estimate a bio-information value based on the valid spectra.

Подробнее
Номер записи: 100