Catheter drug type menstruation tampon for treating colpitis and preparation method thereof

01-03-2019 дата публикации
Номер:
CN0109394424A
Автор: ZHAO CHUNMEI
Принадлежит: Nantong First Peoples Hospital
Контакты:
Номер заявки: 59-11-20188222
Дата заявки: 26-12-2018

[1]

Technical Field

[2]

The invention relates to the technical field of medical devices, more specifically, it relates to a catheter for treating Vaginitis MDR tampon and its preparation method.

[3]

Background Art

[4]

Vaginitis is vaginal inflammation, is lead to the vulvovaginal symptoms such as pruritus, burning pain, stimulate and abnormal liquid to a group of disorders. Normal healthy women anatomy of the vagina due to the characteristics of the pathogen invasion of the natural defense function. Such as the vaginal opening closed, close to the front and back walls of the vagina, vaginal epithelial cell in estrogen under the influence of the hyperplasia and surface layer cell keratinization, vaginal pH value to keep balance, to make the adaptive alkaline pathogen propagation is inhibited, while the neck mucus is alkaline, when the vagina of the natural defense function is damaged, the invasion of pathogens is easy, leading to vaginal inflammation.

[5]

Vaginitis medicine such as in the dregs of the effervescent tablet form, there will be some patients vaginal burning pain, pruritus or other mucosal irritation; gel such medicine is easy to flow out, not only lost potency, fails to reach the therapeutic effect, but also pollution underpants. Vaginal drug lavage although can eliminate the abnormal white in the vagina, but drug for a long time remained in the vagina, can not give full play the potency, to this end, provides a conduit for treating Vaginitis MDR tampon and its preparation method.

[6]

Content of the invention

[7]

In view of the shortcomings of the prior art, the purpose of this invention is to provide a catheter for treating Vaginitis MDR tampon and its preparation method, not only the preparation method is simple, it is easy to realize, can also is that the medicament is the continuing role of the cervix and the vaginal wall, so that the uterine neck, the whole vaginal wall and behind the can contact the drug, drug action lasting, and the medicine will not be flowed out, will not influence the potency, will not pollute the underpants, when in menstruating women, not only can be used for treating Vaginitis, also can absorb the menstrual blood, so the menstrual period can also be used, to the repeated attack other external Vaginitis has already formed the drug-resistant, the conduit can be used for treating MDR hygiene bolt, will not form the drug resistance.

[8]

To achieve the above object, the present invention provides the following technical solutions:

[9]

A catheter for treating Vaginitis MDR tampon, comprises an outer tube, said one end of the outer is in the shape of a closed structure, and the other end of the outer tube is the structure of opening, said outer tube is ellipsoidal closed structure cutting one end of the four petal-shaped wiring harness, and the conduit which is adjacent to the inside of one end of the oval closed structure is inserted movably into the tampon, the tampon adjacent to the conduit is in the shape of one end of the closed structure is an elliptical structure, and the sliver is an elliptical structure one end of the coated with one layer of the external, said outer tube is the opening structure of the internal inserted movably into the one end of the inner tube, the inner tube and one end of the other end of the tampon of the subject, and the other end of said internal pipe extending to the outside of the outer tube is fixedly connected with a push rod.

[10]

By adopting the technical scheme, the outer tube used for protective tampon, the tampon is isolated from the outside, and can effectively prevent the hand contact tampon cause pollution problems; four petal-shaped arc-shaped sheet has better closing function, can prevent the is located in the inside of the outer tube tampon self-exposed by cause the pollution phenomenon, and when in the push the push rod, and also can ensure the tampon can be smoothly introduced; the inner pipe is not only used for the open end of the outer tube closed, also plays a role of guiding, the push rod can be guided to smoothly enter into the outer tube of the interior of the sanitary tampon launch, traditional Chinese medicine layer has clearing, the efficacy of the necrotic tissue, into the vagina can make the medicament for cervical and the role of the vaginal wall, will not affect the efficacy of the drugs out, ensuring sufficient drug loading, the role of the female genitalia is easy to be used for the skin and mucous membrane absorption, not only on cervical erosion and various vaginal bacteria caused by inflammation has antibacterial and anti-inflammation, but also through the decay removing, myogenic and function of converging can effectively promote the cervical epithelial cell growth and the healing of Hyperemia, to achieve the effect of both the incidental, to the repeated attack other external Vaginitis has already formed the drug-resistant, can be the usage of the drug, will not form the drug resistance.

[11]

Further, the sanitary tampon that the other end is fixedly connected with a cotton rope, the away from the tampon are sequentially passes through the inner tube and the push rod extends to the outside of the outer tube.

[12]

By adopting the technical scheme, is convenient when replacement of the tampon, the tampon is pulled out through the cotton rope.

[13]

Further, the push rod is provided for the internal center of the useful passes through the channel.

[14]

By adopting the technical scheme, is convenient to utilize a channel will be cotton rope out, to prevent the cotton rope disordered piled up in the inside of the inner tube of the outer tube is clamped, can be avoided without moving the push rod, so as to avoid the tampon cannot be launched, to avoid affecting the use.

[15]

Further, the tube of the conduit close to the opening of the one end of the structure it is also integrally provided with a necking, and the conduit is the structure of opening of one end of the trumpet-shaped limiting ring is also integrally provided.

[16]

By adopting the technical scheme, necking can not only save processing material, also a role of guidance, can guide the inner pipe in the outer pipe to the internal stability of the mobile.

[17]

Further, the inner diameter of the states shrinks with the mouth of the equal to the outside diameter of said inner tube.

[18]

By adopting the technical scheme, so that the outer surface of the inner tube with the inner surface of the necking better joint, can be prevented from being moved to the inside of the outer pipe and the inner pipe of shaking.

[19]

Further, the push rod away from the inner tube is integrally provided with one end of the trumpet-shaped retaining ring.

[20]

By adopting the technical scheme, the trumpet-shaped retainer ring and the horn of the limiting ring to match and use, can prevent the push rod fully enter the inside of the outer tube, can avoid being unable to push rod is operated.

[21]

Further, the horn ring outer diameter greater than the outer diameter of the horn of the limiting ring.

[22]

By adopting the technical scheme, the trumpet-shaped limiting ring can be ensured to the limiting function of the trumpet-shaped retainer ring, prevent the rod fully enter the inside of the outer tube.

[23]

Further, the traditional Chinese medicine layer is prepared by following method:

[24]

Taking the following raw materials according to the weight of the weighing: solidago 2 parts, matrine 2 parts, raw root 1 parts, pseudolarix 1 parts, fructus cnidii 1 parts, fruit 1 parts, white fresh skin 1 parts, fried cortex Phellodendri 1 parts and medicine pill 1 parts;

[25]

S1, weighed and a solidago, matrine, raw root, vagina, fructus cnidii, fruit, white fresh skin, fried cortex Phellodendri and medicine pill cleaning of the drying and grinding, make the medicinal powder;

[26]

S2, the step S1 to make the crude drugs of the powder into the 300 ml in the Erlenmeyer flask, add 95% ethanol 150 ml, at room temperature is maintained at 25 - 30 °C ultrasonic extraction under the condition of 60 - 80 minutes, using 1 um Millipore filter membrane filter, prepared extract filtrate;

[27]

S3, the step S2 of the extract prepared in the filtrate is added into the beaker, the use of alcohol to dryness, to obtain the extract extract;

[28]

S4, the step S3 of the methanol extract prepared extract completely dissolved after filtering, the filtrate into 500 ml bottle in the capacity of the volume to the scale line, then 0.5 um Millipore filter membrane filter, make the extract;

[29]

S5, the step S4 of the prepared extract into the internal plus 300 ml gel liquid in the beaker, adopts the glass rod stirring, to obtain a gel of traditional Chinese medicine;

[30]

S6, step S5 made of traditional Chinese medicine, adopts the glass rod evenly coated with the tampon is an elliptical structure one end of the external, make the medicine layer.

[31]

By adopting the technical scheme, so that the medicine layer preparation method is simple, it is easy to realize, traditional Chinese medicine layer inside the extraction of the drug can act on the uterus and the vaginal wall, so that the uterine neck, the whole vaginal wall and behind the can contact the drug, drug action lasting, and the medicine will not be flowed out, will not influence the potency, will not pollute the underpants, when in menstruating women, not only can be used for treating Vaginitis, also can absorb the menstrual blood, so the menstrual period can also be used, for the repeated attack other external Vaginitis has already formed the drug-resistant, can be used for the traditional Chinese medicine layer, will not form the drug-resistant, and the traditional Chinese medicine layer without any stimulation and toxic side effects, is a safe and reliable Chinese medicine preparation for external use.

[32]

Further, the states the gelatin fluid is prepared by following method:

[33]

Taking the following raw materials according to the weight of the weighing: acrylic acid cross-linked resin 10 - 12 parts, triethanolamine 12 - 14 parts, glycerin 60 - 80 parts, peregal 50 - 60 parts, sodium bisulfite 0.5 - 1 parts, disodium edetate of 0.5 - 1 parts, Laurel azone 8 - 10 parts and distilled water 300 - 500 parts;

[34]

A, under the normal temperature will be triethanolamine, glycerol, mediocre, distilled water, sodium bisulfite and disodium edetate and Laurel azone into beaker, using a glass stir rod until the presence of solids-free;

[35]

B, in the stirring slowly adding acrylic acid cross-linked resin, until the acrylic acid cross-linked resin is completely dissolved, make the reclaim glue.

[36]

By adopting the technical scheme, for the preparation of the gel liquid method is relatively simple, easy to realize, and the preparation of the coagulant liquid gel effect is good, thereby ensuring that the therapeutic effect of the defecation.

[37]

The invention also provides a catheter for treating Vaginitis MDR ear preparation method, comprises the following steps:

[38]

1st step, using the injection molding machine for preparing polyethylene material of the outer tube and the inner tube of polyethylene material and polyethylene material of the push rod, the nozzle of the injection molding machine at a temperature of 170 - 180 °C, die temperature is 30 - 40 °C, the injection pressure is 50 - 100 mpa, the injection time is 15 - 20 the s, cooling time 12 - 16 the s, rotating speed of the screw is 30 - 50 rpm;

[39]

2nd step, to one end of the purchased directly on the market with is an elliptical structure of one end of the tampon, adopts the glass rod evenly in the tampon is an elliptical structure one end of the wires is external coating;

[40]

3rd step, coated with one layer of the tampon is inserted into the inside of the outer tube;

[41]

4th step, the push rod wherein one end of the glue package in one end of the inner tube, and then the cotton rope passes through the inner tube and the push rod, and then the push rod and the inner tube of the assembly is inserted into the inside of the outer tube, and so that one end of the inner tube with one end of the tampon of the conflict, for holding the plunger in the outside of the outer tube, to obtain the catheter for treating the Vaginitis MDR sanitary tampon.

[42]

By adopting the technical scheme, for the preparation of the catheter for treating the Vaginitis MDR tampon method is relatively simple, and the manufacturing cost is low, conducive to the promotion and universal.

[43]

To sum up, the invention mainly has the following advantages:

[44]

1. The invention, the outer tube used for protective tampon, the tampon is isolated from the outside, and can effectively prevent the hand contact tampon cause pollution problems;

[45]

2. The invention, four petal-shaped arc-shaped sheet has better closing function, can prevent the is located in the inside of the outer tube tampon self-exposed by cause the pollution phenomenon, and when in the push the push rod, and also can ensure the tampon can be smoothly introduced;

[46]

3. The invention, is not only used for the inner open end of the outer tube closed, also plays a role of guiding, the push rod can be guided to smoothly enter into the outer tube of the interior of the sanitary tampon launch;

[47]

4. The invention, traditional Chinese medicine layer has clearing, the efficacy of the necrotic tissue, into the vagina can make its internal drug role for the uterus and the vaginal wall, will not affect the efficacy of the drugs out, ensuring sufficient drug loading, the role of the female genitalia is easy to be used for the skin and mucous membrane absorption, not only on cervical erosion and various vaginal bacteria caused by inflammation has antibacterial and anti-inflammation, but also through the decay removing, myogenic and function of converging can effectively promote the cervical epithelial cell growth and the healing of Hyperemia, reach the specimen the incidental effect, for the repeated attack other external Vaginitis has already formed the drug-resistant, can be the usage of the drug, will not form the drug-resistant, the traditional Chinese medicine layer without any stimulation and toxic side effects, is a safe and reliable Chinese medicine preparation for external use.

[48]

5. The invention, preparing gel liquid method is relatively simple, easy to realize, and the preparation of the coagulant liquid gel effect is good, thereby ensuring that the therapeutic effect of the defecation;

[49]

6. The invention, preparation for treating Vaginitis MDR tampon of the conduit method is relatively simple, and the manufacturing cost is low, conducive to the promotion and universal.

[50]

Description of drawings

[51]

Figure 1 is the structure diagram of an embodiment of the invention;

[52]

Figure 2 is the side-view structure diagram of an embodiment of the invention;

[53]

Figure 3 is the side-view section view structure diagram of an embodiment of the invention;

[54]

Figure 4 is the three-dimensional structure diagram of Figure 3;

[55]

Figure 5 is the explosive structure diagram of an embodiment of the invention;

[56]

Figure 6 is the structure diagram of the invention according to an embodiment of the outer tube;

[57]

Figure 7 is the amplifying structure diagram of A at in Figure 6;

[58]

Figure 8 is the structure diagram of the invention according to an embodiment of the push rod.

[59]

In the Figure: 1, outer tube; 2, the inner pipe; 3, push rod; 4, the cotton rope; 5, tampon; 6, the defecation; 7, the necking; 8, the trumpet-shaped handles; 9, a petal-shaped wiring harness; 10, the trumpet-shaped retaining ring; 11, channel.

[60]

Mode of execution

[61]

Embodiment 1

[62]

The following Figure 1 - 8 of the present invention for further detailed description.

[63]

A catheter for treating Vaginitis MDR tampon, as shown in Figure 1-8, comprises an outer tube 1, the outer tube 1 is in the shape of one end of the closed structure, and the outer pipe 1 and the other end is the structure of opening, said outer conduit 1 is in the shape of one end of the closed structure is provided with four petal-shaped wiring harness cut 9, and the conduit 1 which is adjacent to the inside of one end of the oval closed structure is inserted movably into the tampon 5, the tampon 5 close to the conduit 1 is in the shape of one end of the closed structure is an elliptical structure, and the sliver 5 is an elliptical structure of external coated with one layer of one end 6, the outer tube 1 is the structure of opening one end of an inner pipe is inserted into the internal activities 2, the inner tube 2 and one end of tampon 5 the other end of the conflict, and said internal pipe 2 extending to the other end of the outer conduit 1 fixedly connected with the outside of the push rod 3.

[64]

The outer tube 1 used for protective tampon 5, so that the tampon 5 is isolated from the outside, and can effectively prevent the hand contact tampon 5 cause the problem of pollution; four petal-shaped wiring harness 9 has better closing function, can prevent the is located in the outer tube 1 in the interior of the sanitary tampon 5 exposed lead-contaminated phenomenon, and in the push the push rod 3 when, and also can ensure the tampon 5 can be smoothly introduced; the inner tube 2 is not only used for the outer tube 1 of the open end to seal, also plays a role of guiding, to guide the push rod 3 to smoothly enter into the outer tube 1 of the interior of the sanitary tampon 5 launch, medicine layer 6 has clearing, the efficacy of the necrotic tissue, into the vagina can make the medicament for cervical and the role of the vaginal wall, will not affect the efficacy of the drugs out, ensuring sufficient drug loading, the role of the female genitalia is easy to be used for the skin and mucous membrane absorption, not only on cervical erosion and various vaginal bacteria caused by inflammation has antibacterial and anti-inflammation, but also through the decay removing, myogenic and function of converging can effectively promote the cervical epithelial cell growth and the healing of Hyperemia, achieve the effect of both the incidental, to the repeated attack other external Vaginitis has already formed the drug-resistant, can use the medicine layer 6 treatment, will not form the drug resistance.

[65]

Preferably, the tampon 5 that the other end is fixedly connected with a cotton rope 4, the 4 away from the tampon 5 are sequentially passes through the inner pipe 2 and the push rod 3 extend to the outer conduit 1 external. In the convenient replacement of the tampon 5 when, through the cotton rope 4 the tampon 5 pulled out.

[66]

Preferably, the push rod 3 in the middle of the opening inside the useful for 4 passes through the channel 11. It is convenient to use channel 11 will be cotton rope 4 extraction, prevent the cotton rope 4 of the disorderly pile up in the outer pipe 1 of the internal clamp the inner tube 2, can be avoided 3 can not be moved, so as to avoid the tampon 5 cannot be launched, to avoid affecting the use.

[67]

Preferably, the outer tube 1 of the opening of the tube body close to the one end of the structure it is also integrally provided necking 7, and the conduit 1 is the structure of opening of one end of the trumpet-shaped limiting ring is also integrally provided 8. Necking 7 can not only save processing material, also a role of guidance, can guide the inner tube 2 in the outer pipe 1 to the internal stability of the mobile.

[68]

Preferably, the mouth of the 7 with the inner diameter of the inner tube 2 of the equal to the outside diameter. So that the inner pipe 2 with the outer surface of the necking can be 7 of the inner surface of the attached to the good, can prevent the inner tube 2 in the outer tube 1 is moved to the inside of shaking.

[69]

Preferably, the push rod 3 away from the inner pipe 2 of one end of the part is integrally provided with a trumpet-shaped retaining ring 10. The trumpet-shaped retaining ring 10 with the trumpet-shaped handles 8 to match and use, can prevent the push rod fully enter into the outer tube 1 of the internal, can avoid being unable to push rod is operated 3.

[70]

Preferably, the horn ring 10 is greater than the outer diameter of the horn handles 8 of the outer diameter. The trumpet-shaped claws can ensure the 8 to the trumpet-shaped retainer ring 10 the limiting function of the, prevent the rod completely into the outer tube 1 of the internal.

[71]

Preferably, the medicine layer 6 is prepared by following method:

[72]

Taking the following raw materials according to the weight of the weighing: solidago 2 parts, matrine 2 parts, raw root 1 parts, pseudolarix 1 parts, fructus cnidii 1 parts, fruit 1 parts, white fresh skin 1 parts, fried cortex Phellodendri 1 parts and medicine pill 1 parts;

[73]

S1, weighed and a solidago, matrine, raw root, vagina, fructus cnidii, fruit, white fresh skin, fried cortex Phellodendri and medicine pill cleaning of the drying and grinding, make the medicinal powder;

[74]

S2, the step S1 to make the crude drugs of the powder into the 300 ml in the Erlenmeyer flask, add 95% ethanol 150 ml, at room temperature is maintained at 25 °C under the conditions of the ultrasonic extraction 80 min, using 1 um Millipore filter membrane filter, prepared extract filtrate;

[75]

S3, the step S2 of the extract prepared in the filtrate is added into the beaker, the use of alcohol to dryness, to obtain the extract extract;

[76]

S4, the step S3 of the methanol extract prepared extract completely dissolved after filtering, the filtrate into 500 ml bottle in the capacity of the volume to the scale line, then 0.5 um Millipore filter membrane filter, make the extract;

[77]

S5, the step S4 of the prepared extract into the internal plus 300 ml gel liquid in the beaker, adopts the glass rod stirring, to obtain a gel of traditional Chinese medicine;

[78]

S6, step S5 made of traditional Chinese medicine, adopts the glass rod evenly coated with the tampon 5 is an elliptical structure one end of the external, make the medicine layer 6.

[79]

Preferably, the coagulant liquid is prepared by following method:

[80]

Taking the following raw materials according to the weight of the weighing: acrylic acid cross-linked resin 10 parts, triethanolamine 12 parts, glycerin 60 parts, peregal 50 parts, sodium bisulfite 0.5 parts, disodium edetate of 0.5 parts, Laurel azone 8 parts and distilled water 300 parts;

[81]

A, under the normal temperature will be triethanolamine, glycerol, mediocre, distilled water, sodium bisulfite and disodium edetate and Laurel azone into beaker, using a glass stir rod until the presence of solids-free;

[82]

B, in the stirring slowly adding acrylic acid cross-linked resin, until the acrylic acid cross-linked resin is completely dissolved, make the reclaim glue.

[83]

By adopting the technical scheme, for the preparation of the gel liquid method is relatively simple, easy to realize, and the preparation of the coagulant liquid gel effect is better, and then guarantee the medicine layer 6 therapeutic effect.

[84]

The invention also provides a catheter for treating Vaginitis MDR ear preparation method, comprises the following steps:

[85]

1st step, using the injection molding machine for preparing polyethylene material of the outer tube 1 and the polyethylene material of the inner tube 2 and the polyethylene material of the push rod 3, the nozzle of the injection molding machine at a temperature of 170 - 180 °C, die temperature is 30 - 40 °C, the injection pressure is 50 - 100 mpa, the injection time is 15 - 20 the s, cooling time 12 - 16 the s, rotating speed of the screw is 30 - 50 rpm;

[86]

2nd step, to one end of the purchased directly on the market with the cotton rope 4 and one end of which is an elliptical structure of tampon 5, adopts the glass rod evenly in the tampon 5 is an elliptical structure one end of the wires is external coating 6;

[87]

3rd step, coated with one layer of 6 of the tampon 5 inserted into the outer tube 1 of the internal;

[88]

4th step, the push rod 3 wherein one end of the glue are encapsulated in the inner pipe 2 at one end, then the cotton rope 4 passes through the inner pipe 2 and the push rod 3, and then the pushing rod 3 and the inner pipe 2 is inserted in the assembly of the outer tube 1 of the internal, and so that the inner pipe 2 with one end of the tampon 5 one end of the conflict, the push rod 3 is maintained in the outer tube 1 to the outside of the, make the catheter for treating the Vaginitis MDR sanitary tampon.

[89]

By adopting the technical scheme, for the preparation of the catheter for treating the Vaginitis MDR tampon method is relatively simple, and the manufacturing cost is low, conducive to the promotion and universal.

[90]

Embodiment 2

[91]

With the embodiment 1 is different in that the Chinese medicine layer 6 is prepared by following method:

[92]

Taking the following raw materials according to the weight of the weighing: solidago 2 parts, matrine 2 parts, raw root 1 parts, pseudolarix 1 parts, fructus cnidii 1 parts, fruit 1 parts, white fresh skin 1 parts, fried cortex Phellodendri 1 parts and medicine pill 1 parts;

[93]

S1, weighed and a solidago, matrine, raw root, vagina, fructus cnidii, fruit, white fresh skin, fried cortex Phellodendri and medicine pill cleaning of the drying and grinding, make the medicinal powder;

[94]

S2, the step S1 to make the crude drugs of the powder into the 300 ml in the Erlenmeyer flask, add 95% ethanol 150 ml, at room temperature is maintained at 28 °C ultrasonic extraction under the condition of 70 min, using 1 um Millipore filter membrane filter, prepared extract filtrate;

[95]

S3, the step S2 of the extract prepared in the filtrate is added into the beaker, the use of alcohol to dryness, to obtain the extract extract;

[96]

S4, the step S3 of the methanol extract prepared extract completely dissolved after filtering, the filtrate into 500 ml bottle in the capacity of the volume to the scale line, then 0.5 um Millipore filter membrane filter, make the extract;

[97]

S5, the step S4 of the prepared extract into the internal plus 300 ml gel liquid in the beaker, adopts the glass rod stirring, to obtain a gel of traditional Chinese medicine;

[98]

S6, step S5 made of traditional Chinese medicine, adopts the glass rod evenly coated with the tampon 5 is an elliptical structure one end of the external, make the medicine layer 6.

[99]

By adopting the technical scheme, so that the medicine layer 6 of preparation method is simple, it is easy to realize, one layer of 6 the internal extraction of the drug can act on the uterine neck and the vaginal wall, so that the uterine neck, the whole vaginal wall and behind the can contact the drug, drug action lasting, and the medicine will not be flowed out, will not influence the potency, will not pollute the underpants, when in menstruating women, not only can be used for treating Vaginitis, also can absorb the menstrual blood, so the menstrual period can also be used, for the repeated attack other external Vaginitis has already formed the drug-resistant, can be used for the traditional Chinese medicine layer, will not form the drug-resistant, and the medicine layer 6 without any stimulation and toxic side effects, is a safe and reliable Chinese medicine preparation for external use.

[100]

Preferably, the coagulant liquid is prepared by following method:

[101]

Taking the following raw materials according to the weight of the weighing: acrylic acid cross-linked resin 11 parts, triethanolamine 13 parts, glycerin 70 parts, peregal 55 parts, sodium bisulfite 0.8 parts, disodium edetate of 0.8 parts, Laurel azone 9 parts and distilled water 400 parts;

[102]

A, under the normal temperature will be triethanolamine, glycerol, mediocre, distilled water, sodium bisulfite and disodium edetate and Laurel azone into beaker, using a glass stir rod until the presence of solids-free;

[103]

B, in the stirring slowly adding acrylic acid cross-linked resin, until the acrylic acid cross-linked resin is completely dissolved, make the reclaim glue.

[104]

By adopting the technical scheme, for the preparation of the gel liquid method is relatively simple, easy to realize, and the preparation of the coagulant liquid gel effect is better, and then guarantee the medicine layer 6 therapeutic effect.

[105]

Embodiment 3

[106]

With the embodiment 1 is different in that the Chinese medicine layer 6 is prepared by following method:

[107]

Taking the following raw materials according to the weight of the weighing: solidago 2 parts, matrine 2 parts, raw root 1 parts, pseudolarix 1 parts, fructus cnidii 1 parts, fruit 1 parts, white fresh skin 1 parts, fried cortex Phellodendri 1 parts and medicine pill 1 parts;

[108]

S1, weighed and a solidago, matrine, raw root, vagina, fructus cnidii, fruit, white fresh skin, fried cortex Phellodendri and medicine pill cleaning of the drying and grinding, make the medicinal powder;

[109]

S2, the step S1 to make the crude drugs of the powder into the 300 ml in the Erlenmeyer flask, add 95% ethanol 150 ml, at room temperature is maintained in the 30 °C ultrasonic extraction under the condition of 60 min, using 1 um Millipore filter membrane filter, prepared extract filtrate;

[110]

S3, the step S2 of the extract prepared in the filtrate is added into the beaker, the use of alcohol to dryness, to obtain the extract extract;

[111]

S4, the step S3 of the methanol extract prepared extract completely dissolved after filtering, the filtrate into 500 ml bottle in the capacity of the volume to the scale line, then 0.5 um Millipore filter membrane filter, make the extract;

[112]

S5, the step S4 of the prepared extract into the internal plus 300 ml gel liquid in the beaker, adopts the glass rod stirring, to obtain a gel of traditional Chinese medicine;

[113]

S6, step S5 made of traditional Chinese medicine, adopts the glass rod evenly coated with the tampon 5 is an elliptical structure one end of the external, make the medicine layer 6.

[114]

By adopting the technical scheme, so that the medicine layer 6 of preparation method is simple, it is easy to realize, one layer of 6 the internal extraction of the drug can act on the uterine neck and the vaginal wall, so that the uterine neck, the whole vaginal wall and behind the can contact the drug, drug action lasting, and the medicine will not be flowed out, will not influence the potency, will not pollute the underpants, when in menstruating women, not only can be used for treating Vaginitis, also can absorb the menstrual blood, so the menstrual period can also be used, for the repeated attack other external Vaginitis has already formed the drug-resistant, can be used for the traditional Chinese medicine layer, will not form the drug-resistant, and the medicine layer 6 without any stimulation and toxic side effects, is a safe and reliable Chinese medicine preparation for external use.

[115]

Preferably, the coagulant liquid is prepared by following method:

[116]

Taking the following raw materials according to the weight of the weighing: acrylic acid cross-linked resin 12 parts, triethanolamine 14 parts, glycerin 80 parts, peregal 60 parts, sodium bisulfite 1 parts, disodium edetate of 1 parts, Laurel azone 10 parts and distilled water 500 parts;

[117]

A, under the normal temperature will be triethanolamine, glycerol, mediocre, distilled water, sodium bisulfite and disodium edetate and Laurel azone into beaker, using a glass stir rod until the presence of solids-free;

[118]

B, in the stirring slowly adding acrylic acid cross-linked resin, until the acrylic acid cross-linked resin is completely dissolved, make the reclaim glue.

[119]

By adopting the technical scheme, for the preparation of the gel liquid method is relatively simple, easy to realize, and the preparation of the coagulant liquid gel effect is better, and then guarantee the medicine layer 6 therapeutic effect.

[120]

The embodiment 1 - 3 of the MDR for treating Vaginitis conduit ear using a statistical results in the following table:

[121]

EmbodimentThe use result
1100 People who use the cure 83 people, the cure rate is 83%
2100 People who use the cure 93 people, the cure rate is 93%
3100 People who use the cure 89 people, the cure rate is 89%

[122]

From the above table can know the statistical results of the comparative analysis of the embodiment 2 as an optimum embodiment, by adopting the technical scheme, preparation of Chinese medicine layer 6, its internal medicine can act on the uterus and the vaginal wall, so that the uterine neck, the whole vaginal wall and behind the can contact the drug, drug action lasting, and the medicine will not be flowed out, will not influence the potency, will not pollute the underpants, matching tampon 5 use, when in menstruating women, not only can be used for treating Vaginitis, also can absorb the menstrual blood, so the menstrual period can also be used, for the repeated attack other external Vaginitis has already formed the drug-resistant, can be used for the traditional Chinese medicine layer, will not form the drug-resistant, and the traditional Chinese medicine layer without any stimulation and toxic side effects, is a safe and reliable Chinese medicine preparation for external use.

[123]

The working principle: the conduit for treating Vaginitis MDR tampon, the outer tube 1 used for protective tampon 5, so that the tampon 5 is isolated from the outside, and can effectively prevent the hand contact tampon 5 cause the problem of pollution; four petal-shaped wiring harness 9 has better closing function, can prevent the is located in the outer tube 1 in the interior of the sanitary tampon 5 exposed lead-contaminated phenomenon, and in the push the push rod 3 when, and also can ensure the tampon 5 can be smoothly introduced; the inner tube 2 is not only used for the outer tube 1 of the open end to seal, also plays a role of guiding, to guide the push rod 3 to smoothly enter into the outer tube 1 of the interior of the sanitary tampon 5 launch; medicine layer 6 has clearing, the efficacy of the necrotic tissue, into the vagina can make its internal drug role for the uterus and the vaginal wall, will not affect the efficacy of the drugs out, ensuring sufficient drug loading, the role of the female genitalia is easy to be used for the skin and mucous membrane absorption, not only on cervical erosion and various vaginal bacteria caused by inflammation has antibacterial and anti-inflammation, but also through the decay removing, myogenic and function of converging can effectively promote the cervical epithelial cell growth and the healing of Hyperemia, achieve the effect of fundamental aspects, for the repeated attack other external Vaginitis has already formed the drug-resistant, can be the usage of the drug, will not form the drug-resistant, the traditional Chinese medicine layer without any stimulation and toxic side effects, is a safe and reliable Chinese medicine preparation for external use.

[124]

When in use, the outer tube 1 with an end of the vaginal orifice contact the patient, the operation of the push rod 3 of the inner pipe 2 to the outer tube 1 and the interior of the propulsion, in a manner similar to that of the injection, the tampon 5 and pushed into the vagina in traditional Chinese medicine layer, and then the inner tube 2 and outer tube 1 and the push rod 3 is removed together with the solvent, without changing the, only through the cotton rope 4 the tampon 5 to be pulled out.

[125]

This particular embodiment is only the interpretation of the to this invention, it is not a restriction to the invention, technical personnel in the field after reading the end this specification according to the embodiment of the need to make modifications without creative contribution, but as long as the requirements of the present invention within the scope of the rights are subject to the protection of the Patent law.



[126]

The invention discloses a catheter drug type menstruation tampon for treating colpitis. The catheter drug type menstruation tampon comprises an outer tube. One end of the outer tube is of an oval closed structure, the other end of the outer tube is of an open structure, and four pedal-shaped arc-shaped pieces are cut at one end, of the oval closed structure, of the outer tube. The invention further discloses a preparation method of the catheter drug type menstruation tampon for treating the colpitis. The preparation method is simple and easy to achieve, a drug in a traditional Chinese medicinelayer can continuously act on the cervix uteri and the vaginal wall, the cervix uteri, the whole vaginal wall and the posterior vaginal fornix all can make contact with the drug, the drug effect is durable, the drug cannot flow out, the drug effect cannot be affected, underpants cannot be contaminated, during menstrual onset of a female, the colpitis can be treated, menstrual blood can be absorbed, and therefore the catheter drug type menstruation tampon can be used in the menstrual period; the reoccurring colpitis is resistant to other external drugs, the traditional Chinese medicine layer can be used for treatment, and drug resistance cannot be formed.



1. A catheter for treating Vaginitis MDR tampon, comprises an outer tube (1), characterized in that said outer tube (1) is in the shape of one end of the closed structure, and the outer pipe (1) and the other end is the structure of opening, said outer conduit (1) is in the shape of one end of the closed structure is provided with four petal-shaped wiring harness cut (9), and the conduit (1) adjacent to the inside of which is ellipsoidal closed structure is inserted movably into the one end of the tampon (5), the tampon (5) adjacent to the conduit (1) is in the shape of one end of the closed structure is an elliptical structure, and the sliver (5) is an elliptical structure of external coated with one layer of one end (6), the conduit (1) is the structure of opening one end of an inner pipe is inserted into the internal activities (2), the inner pipe (2) with the one end of the tampon (5) subject to the other end of the, and said internal pipe (2) extends to the other end of the conduit (1) fixedly connected with the outside of the push rod (3).

2. A catheter for treating Vaginitis MDR tampon according to Claim 1, characterized in that the tampon (5) that the other end is fixedly connected with a cotton rope (4), the (4) away from the tampon (5) are sequentially passes through the inner pipe (2) and the push rod (3) extends to the conduit (1) of the external.

3. A catheter for treating Vaginitis MDR tampon according to Claim 2, characterized in that the push rod (3) in the middle of the opening inside the useful for (4) passes through the channel (11).

4. A catheter for treating Vaginitis MDR tampon according to Claim 1, characterized in that said outer tube (1) of the tube body close to the opening of the one end of the structure it is also integrally provided with a necking (7), and the conduit (1) is the structure of opening of one end of the trumpet-shaped limiting ring is also integrally provided (8).

5. A catheter for treating Vaginitis MDR tampon according to Claim 4, characterized in that the mouth of the (7) with the inner diameter of the inner pipe (2) is equal to the outer diameter of the.

6. A catheter for treating Vaginitis MDR tampon according to Claim 1, characterized in that the push rod (3) away from the inner pipe (2) of one end of the horn is integrally provided with the retaining ring (10).

7. A catheter for treating Vaginitis MDR tampon according to Claim 6, characterized in that the horn ring (10) is larger than the outer diameter of the horn handles (8) of the outer diameter.

8. A catheter for treating Vaginitis MDR tampon according to Claim 1, characterized in that the Chinese medicine layer (6) is prepared by following method:

Taking the following raw materials according to the weight of the weighing: solidago 2 parts, matrine 2 parts, raw root 1 parts, pseudolarix 1 parts, fructus cnidii 1 parts, fruit 1 parts, white fresh skin 1 parts, fried cortex Phellodendri 1 parts and medicine pill 1 parts;

S1, weighed and a solidago, matrine, raw root, vagina, fructus cnidii, fruit, white fresh skin, fried cortex Phellodendri and medicine pill cleaning of the drying and grinding, make the medicinal powder;

S2, the step S1 to make the crude drugs of the powder into the 300 ml in the Erlenmeyer flask, add 95% ethanol 150 ml, at room temperature is maintained at 25 - 30 °C ultrasonic extraction under the condition of 60 - 80 minutes, using 1 um Millipore filter membrane filter, prepared extract filtrate;

S3, the step S2 of the extract prepared in the filtrate is added into the beaker, the use of alcohol to dryness, to obtain the extract extract;

S4, the step S3 of the methanol extract prepared extract completely dissolved after filtering, the filtrate into 500 ml bottle in the capacity of the volume to the scale line, then 0.5 um Millipore filter membrane filter, make the extract;

S5, the step S4 of the prepared extract into the internal plus 300 ml gel liquid in the beaker, adopts the glass rod stirring, to obtain a gel of traditional Chinese medicine;

S6, step S5 made of traditional Chinese medicine, adopts the glass rod evenly coated with the tampon (5) is in the shape of one end of the structure and the external, make the medicine layer (6).

9. A preparation method of the defecation according to Claim 8, characterized in that the coagulant liquid is prepared by following method:

Taking the following raw materials according to the weight of the weighing: acrylic acid cross-linked resin 10 - 12 parts, triethanolamine 12 - 14 parts, glycerin 60 - 80 parts, peregal 50 - 60 parts, sodium bisulfite 0.5 - 1 parts, disodium edetate of 0.5 - 1 parts, Laurel azone 8 - 10 parts and distilled water 300 - 500 parts;

A, under the normal temperature will be triethanolamine, glycerol, mediocre, distilled water, sodium bisulfite and disodium edetate and Laurel azone into beaker, using a glass stir rod until the presence of solids-free;

B, in the stirring slowly adding acrylic acid cross-linked resin, until the acrylic acid cross-linked resin is completely dissolved, make the reclaim glue.

10. A catheter for treating the Vaginitis MDR tampon of the preparation method according to Claim 1, characterized in that comprises the following steps:

1st step, using the injection molding machine for preparing polyethylene material of the outer tube (1) and polyethylene material of the inner pipe (2) and the push rod of the polyethylene material (3), said injection molding machine nozzle temperature is 170 - 180 °C, die temperature is 30 - 40 °C, the injection pressure is 50 - 100 mpa, the injection time is 15 - 20 the s, cooling time 12 - 16 the s, rotating speed of the screw is 30 - 50 rpm;

2nd step, to one end of the purchased directly on the market with the cotton rope (4) and one end of the tampon is an elliptical structure (5), by using the glass rod evenly in the tampon (5) is an elliptical structure one end of the wires is external coating (6);

3rd step, coated with one layer of (6) of the tampon (5) inserted into the outer tube (1) of the internal;

4th step, the push rod (3) wherein one end of the glue are encapsulated in the inner pipe (2) at one end, then the cotton rope 4 passes through the inner pipe (2) and push rod (3), and then the pushing rod (3) and the inner pipe (2) of the assembly body is inserted in the outer tube (1) of the internal, and so that the inner pipe (2) and one end of the tampon (5) one end of the conflict, the push rod (3) is maintained in the outer tube (1) to the outside of the, make the catheter for treating the Vaginitis MDR sanitary tampon.