Mix fungicidal.

the II ΐ R.

I-VBE1

the L

i-I-! ' i/2^F. invention relates to fungicidal compositions!

The j'I-

the j it relates more particularly to compositions

II-j-fungicides containing two active ingredients, either;

: - The n - (2.6 to-diméthylrhényl) - Ν - (1 m-e thoxycarbonyl-ethyl) - phénylaûé~

5: tamide (I-) VBE1 The I [j to as fungicide, F.

i-I-conventional - and a fungicide selected from the group comprising; VBE1

I

THE I. the dithiocarbamatee (b.),

, the sterically hindered n-alkylthio-imide (C.),

10. 1 * oxychlorure copper (D.).

the fungicidal compound WITH consisting of n - {2.6 to-dimethylphenyl)

" Ii - (1-methoxycarbonyl-ethyl) - acetamide of formula;

T-

15

? the I

the I 1

THE I!

is described in Italian Patent 25295 j/78 at an HO.

I

kΩ name of the applicant.

i-I the compound has is TiN fungicide with a remarkable•

i-activity against mildew, a low phytotoxicity and

the I

. a systemically active.

The latter characteristic|that offers great interest

]

25|in fungus-control one disadvantage is common

i to all systemic fungicides. 2fe fact, vegetable plants as the activity decreases, the systemic fungicide ôfît less mobile and therefore less effective,

o this makes it necessary to combine the product systemic Μ with other non-systemic fungicides.

In tee during studies regarding the coformulation of the fungicide,

it has been surprisingly found that the combination of said fungicide with known fungicides belonging to the class of dithiocarbamates, confectioneries class n-alkylthio-imide, or consisting of copper oxychloride, results in a synergistic effect, the mixing of the two components with which is remarkably more active than do each of the individual components which the shape at the doses indicated.

The present invention provides synergistic mixtures of compounds a consisting of n - (2.6 to-dimethylphenyl) - n-- (L methoxycarbonyl-êthyl) - phênylacétamide and a compound selected from the group consisting of:

Β-dithiocarbamates,

The c-n-alkylthio-imide,

D oxychloride copper.

Dithiocarbamates (group b) include for example the following compounds:

•Zineb

Maneb•

Nabam•':

•Mancozeb. :

Propineb•:

trade name of ethylene bis-zinc dithiocarbamate;

trade name of ethylene bis-dithiocarbaraate manganese;

trade name of ethylene bis dithiocarbamate sodium trade name of a coordination compound of zinc ions with ethylene bis-dithiocarbamate manganese,, the ratio zinc ions and manganese ions being of 1/8;

trade name of 1^2-propylene bis-zinc dithiocarbamate.

The n-alkylthio-imide (group c) include for example the following compounds:

'•trichloromethylthio: trade name n-trichloromethylthio phthalimide;

•Captan-: trade name n-trichlororaéthylthio to ^ - tétrahydrophtalimidê;

-•Captafol: trade name of n - (1.1_/ 2.2-to-tétrachloroéthylthic) ^ - erffective powerU tétrafiydroph AEG timid.

In the above mixture, the compounds b, c or d are present in amounts of about 3 to 1000 times that of the compound has.

The present invention also relates to fungicidal compositions comprising as active ingredient the aforementioned synergistic mixtures.

In these compositions above, the mixture of the two active substances (compound a and compounds B groups, c or d) in amounts of

of the order of 3 to 90 ¾ by weight.

These compositions are required to infections strong * institutraining of useful plants such as, for example, grape, tobacco, tomatoes, potatoes and other horticultural crops.

The class of fungi (or fungi) the most detrimental because of the damage it causes, which can be attacked victoriously by the subject compositions, is that of Phycomycetes, consisting of:

• Phytophthora β ρρ .,

.•Willwill percnoepora SPPs._T-

• Willwill pseudoperomspora sppet

• Phph.yti.um sPPs.

The fungicidal compositions forming the object of the present invention contain, in addition to the active mixture, other inert materials and optional ** ard, additives. The components of the compositions are essentially selected depending on the composition preparing confectioneries. For example, for preparing a dry powder, it may be sufficient to only add an inert solid such as diatomaceous earth, calcined kaolin, talcum, colloidal silica, sodium carbonate or calcium.

For preparing a wettable powder, may be added to the mixture of active substances:

- solid inert substances such as diatomite (diatomaceous earth) of kaolin, talcum, colloidal silica,

- wetting agents such as alkylaromatic, alkylphêrtols, sorbitan oleates or polyoxyethylates,

- dispersants such as sulphonates or polymethacrylates.

The compositions thus obtained can be used s at doses between 1 and 30 kg/acre.

The choice of increasing compositions suitable and doses used depends on various factors, such as the type of Fungi confectioneries destroying and the type of crop to be treated, the environmental conditions, the means from which provides vaccinica *, andc.

Other advantages and features of the present invention will appear upon reading of the following description and examples are illustrative but non-limiting.

EXAMPLE 1

•method for determining the preventive fungicidal activity against the Plasmopovavitioola (b and c)_} berl and other destinations, on vine plants -<

Grape plants CV Diano, grown in pots in a conditioned atmosphere confectioneries 25 °c 60 ¾ and relative humidity, are sprayed on both sides of their leaves, by a suspension hydroacetonic {% OF ZQ by volume of acetone) products to be tested.

Urt■jdür after treatment, the undersides of the leaves are sprayed with an aqueous suspension of conidés of Plasmopomvitioola (200,000 ' conidés per cm³ ) and are retained during the 24. hours in an enclosure - HU-saturated

5, 21 °c tee at noon.

The plants are then transferred into an enclosure conditioned confectioneries 70ï - 21 °c and V-bis' bîjmiditê for incubation period (7 days) fungal.

^: to there end of this period, the seedlings damage are determined on

⁵ ' here based the surface (bottom faces) converted by the sheets

Letlet us ëbàiplpnons tournaments;

•. The fungicidal activity is expressed as % reduction of infection Λ;, ^ fûrt anhydride in comparison with the plants infested but not prophylactically treated < •and is expressed according to a scale of values included èhtre 100 (plants

"._} Healthy) and 0 (fully Dlantes infested).

EXAMPLE 2

1S - " synergistic effect -

The synergistic effect of fungicidal compounds together is associated

; the greater activity of the mixture of the two constituents by comparison

'. with 1' theoretical activity of a mixture of the two components of non-synergistic

in webs same gear ratios.

20 Theoretical fungicidal activity, expressed as a percentage of reduction of infection [X-theS %>] a mixture of non-synergistic, is calculated by the following formula:

χ (β,, 8), Μ 1 :), №,

As Vf. 100

25 * wherein:

· ¾ to (I-)=fungicidal activity of a constituent pure dose considered,

'; ;.. f.. as a percentage of the reduction of L'infected;

,, CT-VB)=fungicidal activity of the other constituent pure dose considered,_V jv4 ' - - as a percentage of the reduction of infection.

3Û - '. The data in the tables below refer to potency against the Willwill plasmopora vitocola on vine plants,

the values of a and b (the T) the CT) are obtained as well as described in/1' example 1.

Synergism of the mixture of the fungicide: the n - (2# 6 to-dimèthylphènyl) - n-~(1 - "éthdxy" carbonyl éthyO-to-phenylacetamide (has) stored characteristics of the fungicide: Zîneb®? a) activity fongicidéde has [( %) has]:

It ** -!' synergism of the mixture of the fungicide and the fungicide Mancozeb Hancozeb® fungicidal activity (has|):

-•'

. Iii - synergism of the mixture of compound A and Captalo? (d %) -

' has) fungicidal activity captafol cbxî:

30

Synergism of the mixture of compound a and oxychloride has) fungicidal activity of copper oxychloride

b) fungicidal activity of the mixture of a and

EXftiPte ' has

Preparation of powder compositions - bondable mwi

General method. : The various constituents of the composition are mixed together and ' homogenized by grinding in an air jet mill confectioneries adapted-to-5. tfuisant confectioneries to obtain particles having an average size in the range of ', .' 5 e 6 microns thick. According to the present operating above, compositions are prepared given in table I according to:

•VL ' TABLE I

Wettable powder fungicidal compositions

I(proportions expressed in GBP by weight)

Example F.

♦preparation of dry powder compositions -

General method: The components of the composition are mixed together and homogenized by grinding in a ball mill confectioneries.

By operating the aforementioned operative modalities, compositions are prepared as shown in Table II:

TABLE II

Of course, the present invention is by no limited examples and embodiments mentioned above; it is capable of many variations accessible to the ordinarily skilled artisan, depending on each particular application and without does not depart from the spirit of the invention.