Method and apparatus for recapturing an implant from the left atrial appendage

A system and method for retrieving an implantable device includes a delivery catheter, a recapture section, and a sheath. The delivery catheter has a proximal end and a distal end. The recapture section is axially extendable from the distal end of the delivery catheter. The sheath has a proximal end and a distal end and a lumen sized to receive the delivery catheter. A portion of the lumen of the sheath is actuatable from an enlarged inside diameter to a reduced inside diameter to apply an inwardly directed force to the recapture section. The delivery catheter can be actuated with respect to the sheath to extend or retract the recapture section with respect to the delivery catheter.

Occlusion devices and methods

The invention provides intrafallopian devices and non-surgical methods for their placement to prevent conception. The efficacy of the device is enhanced by forming the structure at least in part from copper or copper alloy. The device is anchored within the fallopian tube by a lumen-traversing region of the resilient structure which has helical outer surface, together with a portion of the resilient structure which is biased to form a bent secondary shape, the secondary shape having a larger cross-section than the fallopian tube. The resilient structure is restrained in a straight configuration and transcervically inserted within the fallopian tube, where it is released. Optionally, permanent sterilization s effected by passing a current through there resilisent structure to the tubal walls.

Occluding Device

Techniques are described for occluding the ostium of an appendage. In one example, an implantable medical device for insertion in a left atrial appendage of a patient includes a center hub having a longitudinal axis and a first side and a second side, a plurality of compression springs, each of the plurality of compression springs extending radially from the center hub, and a cover disposed about the compression springs and engaged to center hub on both the first side and the second side.

Systems and methods for making a laminar ventricular partitioning device

Described herein are systems and methods for securing a polymeric sheet to rib components of a frame structure, wherein the rib components are jointed at a hub to form an expandable and collapsible implant. In general, the method may include the steps of decreasing a diameter of the frame structure; placing the frame structure into an assembly fixture, wherein the assembly fixture is configured to hold the frame structure in a loaded configuration with a decreased diameter; placing a polymeric sheet into the assembly fixture; and heating the assembly under pressure to fuse the sheet to the frame structure. In general, a fixture may include a first and second platen having a shaping portion and a rim portion positioned around the periphery of the platen, wherein the shaping portions are configured to hold the rib components of the frame structure in a loaded configuration with a decreased diameter.

Devices and methods for delivering an endocardial device

Described herein are devices, systems and methods for delivering an endocardial device. The systems for delivering the device transvascularly may generally include an elongate guide catheter having a proximal end and a distal end; a conical dilator at the distal end of the elongate guide catheter, the conical dilator being removable to enable delivery of the ventricular portioning device; a delivery catheter having a proximal and distal end; an expansion member near the distal end of the delivery catheter and configured to expand a plurality of struts of the partitioning device; and a coupling element configured to deployably secure to a hub of the partitioning device. The systems for delivering the device transapically may generally include an elongate access sheath; an elongate delivery catheter; an expansion member; and a coupling element proximal to the expansion member and configured to deployably secure to a hub of the partitioning device.

Therapeutic methods and devices following myocardial infarction

Described herein are methods of treating a patient to prevent or correct cardiac remodeling following myocardial infarction. In general these methods may include inserting or implanting a device in a heart chamber to support the affected region within 72 hours after myocardial infarction. The device may be a support device (e.g., a resilient frame) and/or a partitioning device.

Occlusion device for an atrial appendage

Occlusion device for an atrial appendage, the device having proximal and distal ends and a central axis and comprising a cage-like structure formed of struts, the struts having proximal strut ends and distal strut ends, wherein at the proximal end of the device the struts extend towards the central axis and are connected to each other at their proximal strut ends, and wherein at least some of the struts are connected to each other at their distal strut ends within the cage-like structure so that the struts form an atraumatic distal end of the device.

Embolization Plug

Devices and methods that a variety of embolization plugs for treatment of endovascular and non-endovascular defects are disclosed. The plugs have multiple braids that include an outer expandable braid and an inner expandable braid that is located inside the outer expandable braid.

Method and apparatus for treating varicose veins

An apparatus for occluding a blood vessel includes an occluder configured so that at least a portion of the occluder may assume (i) a diametrically-reduced configuration for disposition within the lumen of a tube, and (ii) a diametrically-expanded configuration for disposition adjacent to the blood vessel, such that when the at least a portion of the occluder is in its diametrically-expanded configuration adjacent to the blood vessel, the occluder will cause occlusion of the blood vessel.

Stent-valves for valve replacement and associated methods and systems for surgery

Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided.

MEDICAL APPLICATOR

An applicator for use in the fitting of an occlusive plug of the screw in kind to a fallopian tube, said applicator comprising: a body member; an eyepiece fitted to one end of the body member; an elongate probe carried by, and projecting from the other end of the body member; a fibre optic cable extending from the eye-piece along the interior of the probe to a terminal end of the probe distal from the body member; a nose piece movably mounted at said distal end of the probe and adapted to releasably receive a rear, drive end of an occlusive plug; a mechanical connection extending between the body member and the nose-piece whereby the practitioner may, within limits, vary the angle of the nose-piece with respect to its carrier tube; and a rotational drive means extending between the body member and the nose-piece to apply torque & hence rotational movement to an occlusive plug temporarily held by the nose-piece. 146-. (canceled)47. A medical applicator for use in female sterilisation of a fallopian tube , said applicator comprising:a body member;an elongate probe carried by, and projecting from one end of the body member;a viewing means extending along the probe to an end of the probe distal from the body member;a connector piece movably mounted at said distal end of the probe;means for varying the position of the connector with respect to a main length of said probe; anda rotational drive means extending between the body member and the connector to apply rotational movement to said connector.48. The applicator as claimed in claim 47 , wherein said means for varying the position of said connector comprises a means for actively controlling an angle of connector with respect to a main straight ahead direction of said probe.49. The applicator as claimed in claim 47 , wherein said means for varying the position of the connector comprises a torsion cable for deflecting the end of the probe claim 47 , and a resilient means for biasing the end of the probe to point in a ...

EMBOLISATION SYSTEMS

A bristle device () for delivery into a body lumen comprises a longitudinally extending stem and a plurality of bristles extending generally outwardly from the stem for anchoring the device in a body lumen. There may beat least two bristle segments () and there are flexible sections () between the segments (). The flexible sections () articulate to enable the device to pass through a catheter placed in a tortuous anatomy or to be deployed in a curved vessel, or across a bifurcation. In some cases at least some of the bristle segments () are spaced-apart to accommodate bending of the bristles. 1. An embolisation device for promoting clot formation in a lumen comprising a stem and a plurality of flexible bristles extending outwardly from the stem , the bristles having a contracted delivery configuration and a deployed configuration in which the bristles extend generally radially outwardly from the stem to anchor the device in a lumen , the device comprising a plurality of segments , each of which comprises a plurality of bristles and wherein the device comprises flexible sections between at least some of the bristle segments.2. An embolisation device as claimed in wherein the stem comprises flexible sections between the bristle segments.3. An embolisation device as claimed in or wherein the flexible sections articulate.4. An embolisation device as claimed in any of to wherein a bristle segment in the deployed configuration has a segment diameter claim 1 , a segment length and a bristle density defined by the number of bristles in the segment.5. An embolisation device as claimed in wherein the segment bristle density is from 100 to 1000 per centimetre of segment length.6. An embolisation device as claimed in wherein the segment bristle density is from 100 to 300 claim 5 , optionally 200 to 800 claim 5 , optionally 300 to 800 claim 5 , optionally 200 to 1000 per centimetre of segment length.7. An embolisation device as claimed in any of to wherein the segment diameter ...

IMPLANT RETRIEVAL SYSTEM

Disclosed is an adjustable occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed. 1. A retrieval catheter for retrieving a device from an implantation site within the body, comprising: an elongate, flexible body, having a proximal end and a distal end; a grasping structure on the distal end, for grasping the device; a flared tubular sleeve, for surrounding at least a portion of the device; and an outer tubular sleeve, for surrounding the flared tubular sleeve. This application is a continuation of U.S. patent application Ser. No. 13/617,308, filed Sep. 14, 2012, which is a continuation of U.S. patent application Ser. No. 10/441,600, filed May 19, 2003, now U.S. Pat. No. 8,287,563, which is a divisional of U.S. patent application Ser. No. 10/033,371, filed Oct. 19, 2001, now U.S. Pat. No. 7,044,134, which is a continuation-in-part of U.S. patent application Ser. No. 09/435,562, filed Nov. 8, 1999, now U.S. Pat. No. 7,128,073, the disclosures of which are incorporated in their entirety herein by reference.Embolic stroke is the nation's third leading killer for adults, and is a major cause of disability. There are over 700,000 strokes per year in the United States alone. Of these, roughly 100,000 are hemoragic, and 600,000 are ischemic (either due to vessel narrowing or to embolism). The most common cause of embolie stroke emanating from the heart is thrombus formation due to atrial fibrillation. Approximately 80,000 strokes per year are attributable to atrial fibrillation. Atrial fibrillation is an arrhythmia of the heart that results in a rapid and chaotic heartbeat that produces lower cardiac output and irregular and turbulent blood flow in the vascular system. There are over five million people worldwide with atrial fibrillation, with about four hundred thousand new ...

AN OCCLISIVE MEDICAL IMPLANT

An occlusive medical implant having a frame actuatable between a collapsed delivery configuration and an expanded implanted configuration, the frame including a generally tubular portion with a threaded insert configured to removably attach to a threaded distal end of a core wire; an occlusive element disposed on the frame; where a proximal portion of the occlusive element and the proximalmost extent of the threaded insert are substantially coplanar with a plane defined by three or more proximalmost extents of the frame in the expanded implanted configuration. 1. (canceled)2. A medical implant , comprising:a frame configured to actuate between a collapsed configuration and an expanded configuration,wherein the expanded configuration of the frame is compliant and is configured to substantially conform to a shape and/or geometry of a lateral wall of a left atrial appendage; and to be in sealing engagement therewith when implanted in the left atrial appendage;an occlusive element configured to cover at least a proximal portion of the frame, which proximal portion spans an opening formed by the lateral wall of the left atrial appendage in the expanded configuration of the frame, and is configured to cover at least a portion of the lateral wall of the left atrial appendage distal of the opening;wherein a proximal end of the frame includes a generally tubular portion, the generally tubular portion being configured to attach to a distal end of a core wire;wherein the generally tubular portion of the frame includes a threaded insert coupled thereto,wherein a proximalmost extent of the threaded insert is substantially coplanar with a plane defined by three or more proximalmost extents of the frame in the expanded configuration,wherein the portion of the occlusive element covering the opening is substantially coplanar with the proximalmost extent of the threaded insert and the plane defined by the proximalmost extent of the frame in the expanded configuration.3. The medical ...

System And Method For Implant Delivery

An implant delivery system is described. The implant delivery system utilizes an implant, implant wire, delivery sheath, and a torque device. The torque device may include a cutting element to slit the delivery sheath and a clamp device to fix the position of the implant delivery wire. 1. An implant delivery device , comprising:a delivery sheath having an interior lumen;an implant connected to an elongated implant wire; said implant and said elongated implant wire sized for deployment through said delivery sheath;a torque device having a first passage, a cutting element positioned to cut said delivery sheath, and a second passage splitting off from said second passage so as to separate said delivery sheath from said elongated implant wire.2. The implant delivery system of claim 1 , wherein said torque device further comprises a clamp mechanism configured to prevent said elongated implant wire from movement relative to said torque device.3. The implant delivery system of claim 2 , wherein said clamp mechanism further comprises a collet and a screw member that is selectively contactable with said collet claim 2 , so as to increase or decrease an interior diameter of said collet.4. The implant delivery system of claim 3 , wherein said screw member is threaded onto a proximal end of a body of said torque device.5. The implant delivery system of claim 1 , wherein said cutting element comprises a sharpened edge positioned towards a distal end of said torque device.6. The implant delivery system of claim 1 , wherein said first passage extends between a proximal and distal end of said torque device.7. The implant delivery system of claim 6 , wherein said first passage further extends through a clamp mechanism located near a proximal end of said torque device.8. The implant delivery system of claim 7 , wherein said first passage extends through a collet and screw member of said clamp mechanism.9. The implant delivery system of claim 1 , wherein said implant is an embolic ...

Devices, systems, and methods for pyloric occlusion

An occlusion device or plug having a proximal plug section and a distal plug section. The plug sections may each be shifted between an unexpanded configuration and an expanded configuration at the deployment site to occlude the deployment site. A tubular member such as a silicone tube may be used to form an occlusion device or plug shiftable or expandable into a desired configuration. An intermediate section between a proximal plug section and a distal plug section may be configured to be manipulated at least to shift at least one of the plug sections from an expanded configuration to an unexpanded configuration. A pair of stents may be coupled together via an intermediate section in such manner such that manipulation of the intermediate section causes at least one of the stents to shift from an expanded configuration to an unexpanded configuration.

ATRIAL APPENDAGE BLOOD FILTRATION SYSTEMS

Instrumentation for percutaneous delivery of blood filtration devices to atrial appendages includes a curved access sheath and a delivery tube. The curved access sheath is coursed through the patient's vasculature to gain transseptal access to a left atrial appendage. A compressed filter device attached to a tether wire is loaded in the delivery tube. The loaded delivery tube is advanced through the pre-positioned access sheath to place the device in a deployment position. The access sheath and the delivery tube can be mechanically locked and moved together to place the device in a suitable deployment position. The device is deployed by expelling it from the delivery tube either by retracting the delivery tube over the tether wire, or by moving the tether wire forward through the delivery tube. The expelled device, which is not constrained by the delivery tube walls, self expands to its useful size in the subject atrial appendage. A filter membrane in the deployed extends across the appendage ostium to filter blood flow through the ostium. The filter membrane is configured to present a flat surface to atrial blood flow past the ostium. 1. A blood filtration system for filtering blood flow from an atrial appendage, comprising: a filter device that is configured for deployment in the atrial appendage to intercept blood flow, wherein the filter device has an elastic structure that expands to its natural size from a compressed state when the device is unconstrained; a tubular access sheath for establishing a percutaneous pathway to the atrial appendage; and a delivery instrument for delivering the device through a lumen of the access sheath and for deploying the delivered device in the atrial appendage, wherein the delivery instrument includes: a delivery tube; and a movable tether that passes through the delivery tube, and that is releasably attached to the device, wherein the tether provides mechanical control over the delivery and deployment of the device, and ...

DETACHABLE TREATMENT DEVICE DELIVERY SYSTEM WITH NARROWED DIAMETER REGION AT ATTACHMENT ZONE

A detachable treatment device delivery system includes a delivery sheath defining a lumen, a treatment device having a proximal attachment segment, which includes an enlarged outer diameter region, configured for receipt within the delivery sheath, and a deployment wire configured for receipt within the delivery sheath. A delivery configuration is defined by an overlap of a distal segment of the deployment wire and the enlarged outer diameter region within an attachment zone of the delivery sheath. The deployment wire and the treatment device have a combined outer diameter at the overlap, and, in the delivery configuration, the overlap is proximally spaced from a narrowed diameter region of the attachment zone, which has a smaller diameter than the combined outer diameter. In a deployed configuration, the deployment wire is proximally spaced from the attachment zone, and the proximal attachment segment is permitted to advance through the distal opening. 1. A detachable treatment device delivery system , comprising:a delivery sheath defining a lumen extending from a proximal opening to a distal opening;a treatment device having a proximal attachment segment configured for receipt within the delivery sheath, wherein the proximal attachment segment includes an enlarged outer diameter region; anda deployment wire configured for receipt within the delivery sheath;a delivery configuration defined by an overlap of a distal segment of the deployment wire and the enlarged outer diameter region of the treatment device within an attachment zone defined by the delivery sheath, wherein the deployment wire and the treatment device have a combined outer diameter at the overlap, wherein, in the delivery configuration, the overlap is proximally spaced from a narrowed diameter region of the attachment zone, wherein a diameter of the narrowed diameter region is less than the combined outer diameter;a deployed configuration in which the deployment wire is proximally spaced from the ...

DETACHABLE TREATMENT DEVICE DELIVERY SYSTEM UTILIZING COMPRESSION AT ATTACHMENT ZONE

A detachable treatment device delivery system includes a delivery sheath defining a lumen, a treatment device having a proximal attachment segment configured for receipt within the delivery sheath, and a deployment wire configured for receipt within the delivery sheath. A delivery configuration is defined by an overlap of a distal segment of the deployment wire and the proximal attachment segment within an attachment zone of the delivery sheath. In the delivery configuration, an inner surface of the delivery sheath is outwardly expanded and compressed around the deployment wire and the treatment device at the overlap. In a deployed configuration, the deployment wire is proximally spaced from the attachment zone, and the proximal attachment segment is distally spaced from the attachment zone and the distal opening. 1. A detachable treatment device delivery system , comprising:a delivery sheath defining a lumen extending from a proximal opening to a distal opening;a treatment device having a proximal attachment segment configured for receipt within the delivery sheath; anda deployment wire configured for receipt within the delivery sheath;a delivery configuration defined by an overlap of a distal segment of the deployment wire and the proximal attachment segment of the treatment device along a longitudinal axis of the delivery sheath within an attachment zone defined by the delivery sheath, wherein an inner surface of the delivery sheath defining the attachment zone is outwardly expanded and compressed around the deployment wire and the treatment device at the overlap;a deployed configuration in which the deployment wire is within the delivery sheath and is proximally spaced from the attachment zone, and the proximal attachment segment of the treatment device is distally spaced from the attachment zone and the distal opening.2. The detachable treatment device delivery system of claim 1 , wherein:the delivery sheath defines a single lumen; andthe distal segment of the ...

Cardiac implant anchoring

An implant comprises an anchor that comprises a helical tissue-coupling element. A tool is configured to advance the implant to a heart of a subject, and to position the anchor at tissue of the heart such that the implant extends from the anchor proximally away from the tissue. The tool comprises a tube having a distal end coupled to the implant, and a deployment manipulator. The deployment manipulator extends through the tube to the anchor disposed distally beyond the tube, and is configured to anchor the anchor to the tissue. Presence of the deployment manipulator through the distal end of the tube maintains the coupling between the distal end of the tube and the implant. Other embodiments are also described.

MECHANISM AND DEVICE FOR LEFT ATRIAL APPENDAGE OCCLUSION WITH ELECTRICAL ISOLATION

Left atrial appendage (LAA) occlusion device including a membrane, a plurality of fixation splines and a deployment hub, the plurality of fixation splines for affixing the LAA occlusion device to an ostium of the LAA, the deployment hub being positioned in the membrane, the deployment hub including a threaded aperture and a one-way valve, for enabling a toxin to be entered into the LAA through the deployment hub. 1. Left atrial appendage (LAA) occlusion device comprising:a semi-permeable membrane having semi-permeability in only one direction, for covering an ostium of said LAA; anda deployment hub, positioned in said membrane,wherein said deployment hub comprises a one-way valve, for enabling a toxin to be entered into said LAA through said deployment hub; andwherein said semi-permeable membrane enables said toxin to seep out of said LAA and prevents blood from entering said LAA.2. (canceled)3. The LAA occlusion device according to claim 1 , wherein said semi-permeable membrane has a shape selected from the list consisting of:an umbrella shape;a parachute shape;a circular shape;a balloon shape; anda shape which approximates the anatomy of said ostium of said LAA.4. The LAA occlusion device according to claim 23 , wherein said threaded aperture enables at least one of a catheter and a delivery device to be coupled with said LAA occlusion device for placement in said LAA.5. The LAA occlusion device according to claim 23 , wherein said plurality of fixation splines is made from a biocompatible metal.6. The LAA occlusion device according to claim 23 , wherein said plurality of fixation splines has an open shape and a closed shape.7. The LAA occlusion device according to claim 23 , wherein said plurality of fixation splines is arranged radially around said deployment hub.8. The LAA occlusion device according to claim 23 , wherein said plurality of fixation splines is formed as a spring and is held under pressure by a delivery sheath.9. The LAA occlusion device according ...

NOVEL ENHANCED ZERO DISPLACEMENT OPTIMA® SYSTEM

Data supported zero displacement implant/coil detachment system is, for example, gamma-irradiated post manufacturing, but made with no tension/zero displacement using more than 1 SR thread. 1. An endovascular coil delivery system , which comprises; in combination:more than one SR thread;a co-axial heater coil; andattachment with-zero displacement, meaning zero tension.2. The system of claim 1 , further comprising dual SR threads.3. The system of claim 1 , and all disclosure herein claim 1 , wherein a first SR thread is 18 SR inside the implant; and a second SR thread is 22 SR used for detachment.4. The system of comprising immediate detachment.5. The system of wherein the implant/coil separates outside the microcatheter.6. The system of claim 1 , wherein upon pusher removal implant/coil separates inside microcatheter <1 mm; or wherein upon pusher removal implanticoil separates inside microcatheter >1 mm.7. The system of claim 1 , farther comprising sterilization by gamma irradiation claim 1 , whereby the longer or 22 SR thread shrinks in length claim 1 , creating tension post manufacturing.8. The system of claim 7 , wherein detachment on the first attempt is assured.9. The system of claim 8 , wherein detachment is confirmed by fluoroscopy.10. The system of herein embodied in an Optima® brand of delivery system with implant/coils.11. The system of claim 10 , with tantalum brush and other radiopacity. This application claims the full Paris Convention benefit of, and priority to, U.S. Provisional Patent Application Ser. No. 63/035,075, filed Jun. 5, 2020.The present inventions relate to delivery systems for endovascular devices, particularly the present inventions overcome longstanding issues with respect to coil delivery.It is respectfully proposed that the instant disclosure as shown and described is progress in science and the useful arts deserving of Letters Patent.Corresponding reference characters indicate corresponding components throughout the several views of ...

ATRIAL APPENDAGE OCCLUDER CAPABLE OF ENTERING HALF-RELEASED STATE BY MEANS OF PUSHING HEAD-END FIBER

An atrial appendage occluder capable of entering a half-released state by means of pushing a head-end fiber comprises: an occlude body (); a head-end control fiber (); and a tail-end control fiber (). A head end of the occluder body () is connected to one end of the head-end control fiber () by means of a head-end threaded bushing (). A tail end of the occluder body () is connected to one end of the tail-end control fiber () by means of a tail-end threaded bushing (). The tail-end control fiber () is in the form of a hollow column. The other end of the head-end control fiber () sequentially passes through the tail-end threaded bushing () and the tail-end control fiber (). The occluder body () is in a woven-net support structure, and has a shape preconfigured to match the structure of an atrial appendage after the occluder body () has been fully released. The occluder body () is in the form of a strip and disposed in an outer sheath () before being released. The occluder body () is in a half-release state after being pushed out of the outer sheath (). The diameter of the occluder body () is changed by pushing or pulling the head-end control fiber (). The atrial appendage occluder can adjust its location in the atrial appendage, such that the occluder can be released precisely in a preset location. 1. An atrial appendage occluder capable of entering a semi-release state by pushing a distal cable , comprising an occluder body , a distal control cable and a proximal control cable , and wherein ,a distal end of the occluder body is connected to one end of the distal control cable by means of a distal threaded bushing, and a proximal end of the occluder body is connected to one end of the proximal control cable by means of a proximal threaded bushing; the proximal control cable is in a shape of a hollow column, and the other end of the distal control cable is capable of sequentially passing through the proximal threaded bushing and the proximal control cable; andthe ...

CENTERED BALLOON FOR THE LEFT ATRIAL APPENDAGE

A medical device for reducing the volume of a left atrial appendage (LAA) may include an elongate shaft having a distal portion, and a volume-reducing means expandable from a collapsed to an expanded state, the volume-reducing means being releasably attached to the distal portion. The volume-reducing means may include an actuatable frame and an impermeable covering disposed over the frame. The volume-reducing means may be sized to fit within the LAA in the expanded state while maintaining an open fluid flow path from a distal region through the ostium of the LAA. A medical device may include a second volume-reducing means to be placed within and substantially occlude a distalmost region of the LAA. A method may include inserting a volume-reducing means into the LAA, expanding the volume-reducing means, and positioning the volume-reducing means such that an open fluid flow path is maintained through an entire cycle of the heart. 1. (canceled)2. A volume reducing device for a left atrial appendage comprising:a distal hub;a proximal hub,the distal hub and the proximal hub defining a longitudinal axis therebetween;an actuatable support frame which includes a plurality of struts extending from the distal hub to the proximal hub,wherein the actuatable support frame has a radially collapsed configuration and a radially expanded configuration defining an interior volume sized and configured to fit within the left atrial appendage;a substantially impermeable covering supported by the actuatable support frame,wherein the substantially impermeable covering prevents blood from entering or leaving the interior volume of the radially expanded configuration of the actuatable support frame; anda plurality of anchoring members which extend radially outward from the plurality of struts of the actuatable support frame,wherein the plurality of anchoring members is configured and adapted to anchor and position the volume reducing device in a spaced-apart relationship with a lateral wall ...

Method and apparatus for treating varicose veins

Apparatus for occluding a blood vessel, the apparatus comprising: an occluder, the occluder being configured so that at least a portion of the occluder may assume (i) a diametrically-reduced configuration for disposition within the lumen of a tube, and (ii) a diametrically-expanded configuration for disposition adjacent to the blood vessel, such that when said at least a portion of the occluder is in its diametrically-expanded configuration adjacent to the blood vessel, the occluder will cause occlusion of the blood vessel.

"Bowl-of-Spaghetti" Type Intrasacular Aneurysm Occlusion Device

This invention is a “bowl-of-spaghetti” type intrasacular aneurysm occlusion device including: a catheter; embolic coils; a bowl or cup shaped neck bridge; an opening in the neck bridge through which the coils are inserted into the aneurysm sac; and a closure mechanism which closes the opening after the coils have been inserted into the aneurysm sac. It is a called a “bowl-of-spaghetti” type device because the neck bridge can look like a bowl and the embolic coils can look like spaghetti noodles in the bowl. 1. A “bowl-of-spaghetti” type intrasacular aneurysm occlusion device comprising:a longitudinal lumen which is configured into be inserted into a person's vasculature;one or more longitudinal embolic members which are configured to be delivered through the longitudinal lumen into an aneurysm sac in the person's vasculature;an expandable proximal member which is configured to be inserted into and expanded within the aneurysm sac, expanding to a diameter which is larger than the maximum diameter of the aneurysm neck;an opening in the expandable proximal member through which the longitudinal embolic members are inserted into the aneurysm sac; anda closure mechanism which closes the opening after the longitudinal embolic members have been inserted into the aneurysm sac.2. The device in wherein the longitudinal lumen is a catheter claim 1 , the longitudinal embolic members are embolic coils claim 1 , and the expandable proximal member is a neck bridge.3. The device in wherein the expandable proximal member self expands within the aneurysm sac.4. The device in wherein the expandable proximal member expands into an upward-opening-convex shape.5. The device in wherein the expandable proximal member expands into a bowl or cup shape.6. The device in wherein the expandable proximal member is a neck bridge.7. The device in wherein the neck bridge is a braided or woven stent claim 6 , lattice claim 6 , mesh claim 6 , and/or framework.8. The device in wherein the neck bridge ...

Vaso-occlusive devices including a friction element

Vaso-occlusive apparatuses, including implants, and methods of using them to treat aneurysms. The vaso-occlusive implants described herein include one or more soft and expandable braided member coupled to a pushable member such as a coil that maybe inserted and retrieved from within an aneurism using a delivery catheter as well as a friction element between the soft braided member and the coil. The friction element allows the relatively soft and elongate implant to be pushed out of a cannula without binding up within the cannula.

LEFT ATRIAL APPENDAGE CLOSURE AND DELIVERY SYSTEM THEREOF

A left atrial appendage (LAA) closure () and a system () for delivering the LAA closure are disclosed. The LAA closure () includes supporting struts (), wherein the supporting struts () are distributed peripherally around a first hub () and extend outward, the supporting strut () bifurcates at a first position () into a left branch () and a right branch (). The left branch () of each supporting strut () and the right branch () of an adjacent supporting strut join each other at a second position () and extend distally to form a distal end. The LAA closure further includes a supporting rod () between adjacent supporting struts () which ensures stability, absence of irregular deformation and lateral slippage, of the LAA closure (). With the supporting rods () between the adjacent supporting struts (), the LAA closure () forms a dense mesh which imparts high overall strength of the LAA closure (). 1. A left atrial appendage (LAA) closure , comprising a plurality of supporting struts distributed peripherally around a first hub and extending outwardly from the first hub , the supporting strut bifurcating at a first position into a left branch and a right branch , the left branch of a supporting strut and the right branch of an adjacent supporting strut joining each other at a second position and extending distally to form a distal end , the LAA closure further comprising a supporting rod disposed between adjacent supporting struts.2. The LAA closure according to claim 1 , wherein the supporting rod has a first end connected to the outside of the first hub claim 1 , extending outwardly and bifurcating into a second end and a third end at a third position.3. The LAA closure according to claim 2 , wherein the second end is fixed between the first and second positions of the left branch of the supporting struts claim 2 , and the third end is fixed between the first and second positions of the right branch of the supporting struts.4. The LAA closure according to claim 2 , ...

Expandable occlusion devices and methods of use

An occlusion device and method for occluding an undesirable vascular structure, such as a septal defect or left atrial appendage. The occlusion device includes a lattice structure that expands from a contracted catheter-deliverable state to an expanded state that occludes the vascular structure. The lattice structure has one or more braided layers, with structural braided layers that provide structural support to the device, and occlusive layers that provide a lattice braiding or pore sizes that promote further occlusion by a biological process, such as tissue ingrowth that further occludes the affected vascular structure.

Lung volume-reducing elastic implant and instrument

A lung volume-reducing elastic implant ( 2 ) and a lung volume-reducing instrument; the lung volume-reducing elastic implant ( 2 ) is tubular and comprises a proximal implant end ( 201 ), an elastic deformation part ( 205 ) and a distal implant end ( 202 ); the elastic deformation part ( 205 ) is located between the proximal implant end ( 201 ) and the distal implant end ( 202 ), and the elastic deformation part ( 205 ) has a shape memory characteristic; the lung volume-reducing elastic implant ( 2 ) is opened at the proximal implant end ( 201 ); the elastic deformation part ( 205 ) is provided with a plurality of grooves ( 204 ) at intervals along the longitudinal direction thereof; each groove ( 204 ) communicates with the tube cavity of the elastic deformation part ( 205 ); the lung volume-reducing instrument comprises the lung volume-reducing elastic implant ( 2 ) and a delivery device ( 1 ) matching same; the delivery device ( 1 ) comprises a guidewire ( 101 ) and a hollow push piece ( 110 ); the lung volume-reducing elastic implant ( 2 ) is detachably connected to the distal end of the hollow push piece ( 110 ) via the proximal implant end ( 201 ); and the guidewire ( 101 ) passes through the tube cavity of the lung volume-reducing elastic implant ( 2 ) and the tube cavity of the hollow push piece ( 110 ). The lung volume-reducing instrument is more convenient for an operation and takes shorter time, and avoids damage to the inner wall of the bronchia, reducing the occurrence of pneumothorax.

DEVICE FOR POSITIONING AND RELEASING A CLOSURE IMPLANT FOR CLOSING THE LEFT ATRIAL APPENDAGE

A device for closing the left atrial appendage. The device has a flexible and elongate pulling element fixed to a flexible material layer connected fixed to a self-expanding stent. The closure implant can be drawn back into the lumen of a catheter by the pulling element, and in so doing the stent framework can be transferred into a compressed state. The device enables a monitored and controllable release of the closure implant. 1. A device for closing the left atrial appendage , comprisinga closure implant for closing the left atrial appendage, comprising a self-expandable stent framework, which can be automatically expanded from a compressed state into an expanded state, and wherein the closure implant has a flexible material layer fixed to the stent framework, wherein the material layer in the expanded state of the stent framework is stretched,a catheter with a lumen for receiving the closure implant in the compressed state of the stent framework, wherein the closure implant can be released from the lumen by being slid out, and in so doing the stent framework can be transferred into the expanded state, anda flexible and elongate pulling element fixed to the flexible material layer so that the closure implant can be drawn back into the lumen of the catheter by pulling the pulling element, which causes the stent framework to be transferred into the compressed state.2. The device according to claim 1 , wherein the pulling element comprises a cord or a thread.32d. The device according to claim 1 , wherein the material layer consists of a fabric claim 1 , wherein the pulling element is guided through the fabric of the material layer ().4. The device according to claim 1 , wherein the pulling element has a first and a second end claim 1 , wherein the pulling element has a thickened portion between the two ends claim 1 , so that the pulling element can be pulled out completely from the material layer by pulling on the second end claim 1 , and so that the thickened ...

Devices and methods for occluding abnormal openings in a patient's vasculature

A medical device is provided in which one or both ends of the device encourage the formation of tissue across substantially the entire area of the respective end that is exposed to the blood flow for reducing the risk of a thrombotic embolism. The medical device includes a tubular structure having at least one expanded volume portion and a tapered transition portion. The tubular structure may be made through the braiding of a number of strands, and a first end feature may be used to secure the proximal strand ends. The proximal strand ends may be secured via the proximal end of the first end feature, such that the tapered transition portion is formed over the circumferential surface of the first end feature, and only a proximal end surface (or a portion of the proximal end surface) of the first end feature is exposed to the path of flowing blood.

Atrial appendage blood filtration systems

Instrumentation for percutaneous delivery of blood filtration devices to atrial appendages includes a curved access sheath and a delivery tube. A compressed filter device attached to a tether wire is loaded in the delivery tube. The access sheath and the delivery tube can be mechanically locked and moved together to place the device in a suitable deployment position. The device is deployed by expelling it from the delivery tube either by retracting the delivery tube over the tether wire, or by moving the tether wire forward through the delivery tube. A filter membrane in the deployed device extends across the appendage ostium to filter blood flow through the ostium. The filter membrane is configured to present a flat surface to atrial blood flow past the ostium.

METHOD AND APPARATUS FOR RECAPTURING AN IMPLANT FROM THE LEFT ATRIAL APPENDAGE

A system and method for retrieving an implantable device includes a delivery catheter, a recapture section, and a sheath. The delivery catheter has a proximal end and a distal end. The recapture section is axially extendable from the distal end of the delivery catheter. The sheath has a proximal end and a distal end and a lumen sized to receive the delivery catheter. A portion of the lumen of the sheath is actuatable from an enlarged inside diameter to a reduced inside diameter to apply an inwardly directed force to the recapture section. The delivery catheter can be actuated with respect to the sheath to extend or retract the recapture section with respect to the delivery catheter. 1. (canceled)2. A delivery catheter for a device implantable in a heart , the delivery catheter comprising:a delivery catheter comprising an elongate tubular body, an elongate tubular body proximal end, an elongate tubular body distal end, an elongate tubular body distal portion adjacent the elongate tubular body distal end; anda recapture section connected to the elongate tubular body distal portion,wherein the recapture section has a reduced configuration and an enlarged configuration,wherein the enlarged configuration of the recapture section is adapted and configured to receive at least a portion of a device implantable in a heart.3. The delivery catheter of claim 2 , wherein the delivery catheter is configured and adapted to be releasably coupled to a device implantable in a heart.4. The delivery catheter of claim 2 , further comprising a sheath claim 2 ,wherein the sheath has a radially enlarged configuration in which a distal portion of the sheath has a radial extent sized to receive at least a portion of the device implantable in a heart and a radially contracted distal portion configuration in which the radial extent of the distal portion of the sheath is less than the radial extent of the distal portion of the sheath in the enlarged configuration.5. The delivery catheter of ...

EMBOLIC DEVICE SUITED FOR EASE OF DELIVERY AND PLACEMENT

An embolic device and a corresponding embolic device delivery system and method. In one example, an embolic device delivery system comprises a delivery catheter, a coupler disposed inside the delivery catheter, and an embolic device that may be carried and placed by the coupler. The embolic device includes a primary winding that forms a hollow tube such that a coupler may be threaded therethrough. Further, the embolic device may include a slotted metal tube suited to be affixed to one end of the hollow tube formed by the primary winding. Additionally, the embolic device may include a retaining mechanism that includes one or more protrusions suited to engage with one or more slots of the slotted metal tube. In this manner, the retaining mechanism is affixed to the slotted metal tube and the hollow tube formed by the primary winding. 1. An embolic device , comprising:a primary winding having a coiled member forming a hollow tube structure having a proximal end and a distal end;a slotted metal tube affixed to the primary winding at one of the ends and having a plurality of slots positioned in a body of the slotted metal tube; anda retaining mechanism having a plurality of protrusions and an aperture, the retaining mechanism affixed to the slotted metal tube wherein each slot in the body of the slotted metal tube is coupled to a respective protrusion of the retaining mechanism, the retaining mechanism securely affixed to the slotted metal tube such that the aperture is exposed adjacent to the slotted metal tube.2. The embolic device of claim 1 , wherein the plurality of slots comprises two slots.3. The embolic device of claim 1 , further comprising a coupler orifice disposed in a base portion of the retaining mechanism suited for receiving a coupler wire from an embolic procedure system.4. The embolic device of claim 3 , wherein the coupler orifice comprises a slotted coupler orifice having first and second protruding members disposed adjacent to a slot of eth slotted ...

MEDICAL DEVICE FOR MODIFICATION OF LEFT ATRIAL APPENDAGE AND RELATED SYSTEMS AND METHODS

Devices, methods and systems are provided for occluding an opening within the tissue of a body, such as a left atrial appendage. In one embodiment, a medical device coupled to a delivery catheter includes a fluid flow path that facilitates contrast fluid to pass through the delivery catheter and the medical device to a distal side thereof to provide imaging information as to the position of the medical device positioned in the opening, such as the left atrial appendage. In another embodiment, a medical device is coupled to a delivery catheter, the medical device including flaps adjacent a hub of the medical device that close-off a bore of the hub upon the catheter being detached from the medical device. 1. A medical device system for modifying a left atrial appendage (“LAA”) of a heart , the medical device system comprising:a delivery catheter extending between a proximal end and a distal end; anda medical device removeably coupled to the distal end of the delivery catheter, the medical device including a hub and multiple frame segments extending from the hub, the frame segments including an occluder portion extending over at least a proximal side of the frame segments of the medical device with occluder portion flaps adjacent the hub, the occluder portion flaps configured to be positioned in an open first position and a closed second position such that the occluder portion flaps are in the open first position with the delivery catheter coupled to the medical device and the occluder portion flaps are in the closed second position upon the delivery catheter being removed from the medical device.2. The medical device system of claim 1 , wherein claim 1 , in the closed second position claim 1 , the occluder portion flaps are configured to substantially close-off a bore defined in the hub of the medical device.3. The medical device system of claim 1 , wherein claim 1 , in the closed second position claim 1 , the occluder portion flaps are configured to substantially ...

Closure device for left atrial appendage

A device for closing a left atrial appendage of a patient comprising a containment member having a first configuration for passage into the left atrial appendage and a second larger configuration, and a wire movable into the containment member in situ to expand the containment member in the left atrial appendage to the second configuration.

Percutaneous Catheter Directed Intravascular Occlusion Devices

Embodiments of the present invention provide an improved vascular occlusion device for occlusion of a passageway, cavity, or the like. According to one embodiment, a medical device for occluding a left atrial appendage is provided. The medical device includes a first portion having at least one plane of occlusion that is configured to be positioned outside of the left atrial appendage, and a second portion having at least one plane of occlusion that is configured to be at least partially positioned within a cavity defined by the left atrial appendage. 1. A medical device for occluding a left atrial appendage (“LAA”) , the medical device comprising:a self-expandable occluder body having a scaffolding structure formed of nitinol and being cylindrical or tapered, the medical device having a proximal end portion and a distal end portion, the distal end portion configured to be at least partially positioned within a cavity defined by the LAA;a proximal end fastener coupled to the proximal end portion of the medical device, the proximal end fastener being threaded for reversible coupling to a delivery system;a distal end fastener coupled the distal end portion of the medical device; andan occlusion material coupled to the scaffolding structure,wherein the occluder body has a plurality of retention hooks configured to penetrate into a wall of the LAA, each of the retention hooks having an end oriented toward the proximal end portion of the medical device.2. The medical device of claim 1 , wherein the plurality of retention hooks includes at least six retention hooks.3. The medical device of claim 1 , wherein the occluder body is formed as a laser-cut or etched tube.4. The medical device of claim 1 , wherein the distal end fastener is formed of a radiopaque material for assisting a surgeon in positioning the medical device.5. The medical device of claim 4 , wherein the radiopaque material includes platinum.6. The medical device of claim 4 , wherein the radiopaque material ...

Percutaneous Catheter Directed Intravascular Occlusion Devices

Embodiments of the present invention provide an improved vascular occlusion device for occlusion of a passageway, cavity, or the like. According to one embodiment, a medical device for occluding a left atrial appendage is provided. The medical device includes a first portion having at least one plane of occlusion that is configured to be positioned outside of the left atrial appendage, and a second portion having at least one plane of occlusion that is configured to be at least partially positioned within a cavity defined by the left atrial appendage.

DEVICES, SYSTEMS, AND METHODS FOR TREATING THE LEFT ATRIAL APPENDAGE

Disclosed are embodiments of a method for occluding a left atrial appendage (LAA) and other cavities or openings within a body. Some embodiments of the method can include an implant configured to be deployed within the LAA or other cavity, configured to be expanded or moved against a wall portion of the LAA or other cavity, and configured to twist at least a portion of the LAA or other cavity when the implant is rotated. Thereafter, one or more securing elements, staples, sutures, or other fasteners can be implanted in the gathered tissue to hold the tissue in the gathered state, thereby occluding the opening of the LAA or other cavity. In some embodiments, the opening of the LAA or other cavity can be occluded by elongating or otherwise reshaping the opening using an implant device, and securing the opening in the occluded state. 120-. (canceled)21. A method of treating a left atrial appendage , comprising:rotating the left atrial appendage; andsecuring the left atrial appendage in a rotated position.22. The method of claim 21 , wherein rotating the left atrial appendage comprises rotating the left atrial appendage to deform or occlude the left atrial appendage.23. The method of claim 21 , wherein securing the left atrial appendage in a rotated position comprises securing the left atrial appendage in a rotated position in which the left atrial appendage is reduced in volume.24. The method of claim 21 , wherein securing the left atrial appendage in a rotated position comprises securing the left atrial appendage in a rotated position in which the left atrial appendage is deformed or occluded.25. The method of claim 21 , wherein rotating the left atrial appendage comprises bending or contorting the left atrial appendage.26. The method of claim 21 , wherein securing the left atrial appendage in a rotated position comprises securing the left atrial appendage in a position in which a blood communication between the left atrial appendage and a left atrium is inhibited ...

Left atrial appendage closure and delivery system thereof

A left atrial appendage (LAA) closure (1) and a system (6) for delivering the LAA closure are disclosed. The LAA closure (1) includes supporting struts (11), wherein the supporting struts (11) are distributed peripherally around a first hub (10) and extend outward, the supporting strut (11) bifurcates at a first position (110) into a left branch (111) and a right branch (112). The left branch (111) of each supporting strut (11) and the right branch (112) of an adjacent supporting strut join each other at a second position (113) and extend distally to form a distal end. The LAA closure further includes a supporting rod (12) between adjacent supporting struts (11) which ensures stability, absence of irregular deformation and lateral slippage, of the LAA closure (1). With the supporting rods (12) between the adjacent supporting struts (11), the LAA closure (1) forms a dense mesh which imparts high overall strength of the LAA closure (1).

Filamentary devices for treatment of vascular defects

Methods for treatment of a cerebral aneurysm are described. Methods include providing a self-expanding permeable shell having a radially constrained elongated state configured for delivery within a catheter lumen, an expanded state with a globular and longitudinally shortened configuration relative to the radially constrained state, and a plurality of elongate filaments that are woven together, which define a cavity of the permeable shell. The permeable shell includes composite filaments. The composite filaments may have a diameter of 0.00075″, 0.001″, 0.0015″, and/or 0.00125″. The permeable shell is advanced in the constrained state within a catheter. The permeable shell is then deploying the permeable shell within the cerebral aneurysm, wherein the permeable shell expands to the expanded state within the cerebral aneurysm. The catheter is then withdrawn after deploying the permeable shell.

Embolic implant and method of use

A parent artery occlusion (PAO) device which provides for immediate occlusion of a cerebral artery to isolate a defect. The PAO device includes a self-expanding wire-frame prolate structure which is partially covered with an ePTFE membrane.

RETRIEVAL WIRE CENTERING DEVICE

An occlusive implant system may include a catheter having a lumen extending therethrough, a core wire slidably and rotatably disposed within the lumen, the core wire having a threaded member disposed at a distal end, and a medical implant having an expandable frame, an occlusive element disposed on the frame, and a threaded insert coupled to a proximal portion of the frame, wherein the threaded member is removably coupled to the threaded insert. 1. A medical implant , comprising:a frame configured to actuate between a collapsed configuration and an expanded configuration; andan occlusive element covering at least a portion of the frame;wherein a proximal end of the frame forms a generally tubular portion, the tubular portion being configured to attach to a distal end of a core wire;wherein the tubular portion of the frame includes a threaded insert coupled thereto.2. The implant of claim 1 , wherein the frame includes an annular collar member at least partially disposed within the tubular portion and coupled thereto claim 1 , the threaded insert being coupled to the annular collar member.3. The implant of claim 2 , wherein the threaded insert is disposed within the annular collar member.4. The implant of claim 3 , wherein a portion of the occlusive element is disposed between the threaded insert and the annular collar member.5. The implant of claim 2 , further including a pin element coupling the annular collar member to the frame.6. The implant of claim 1 , wherein the frame includes a plurality of proximally-facing hooks disposed about a periphery of the frame in the expanded configuration.7. The implant of claim 4 , wherein the threaded insert is disposed distally of a portion of the occlusive element disposed outside of the annular collar member.8. The implant of claim 4 , wherein an outer portion of the occlusive element is defined as that part of the occlusive element disposed outside of the annular collar member claim 4 , wherein the outer portion of the ...

AN IMPLANT SYSTEM COMPRISING A DELIVERY WIRE ASSEMBLY AND AN IMPLANT

There is provided an implant system comprising: a delivery wire assembly having a female detachment mechanism component; and an implant having a male detachment mechanism component, wherein the female detachment mechanism component comprises a coil configured to receive the male detachment mechanism component such that the male detachment mechanism component is attachable to the female detachment mechanism component. 1. An implant system comprising:a delivery wire assembly having a female detachment mechanism component; andan implant having a male detachment mechanism component,wherein the female detachment mechanism component comprises a coil configured to receive the male detachment mechanism component such that the male detachment mechanism component is attachable to the female detachment mechanism component;wherein the female detachment mechanism component further comprises a cylinder defining an internal bore, and wherein the coil is disposed within the internal bore of the cylinder, and at least a portion of the coil is free to translate in along the length of the internal bore.2. The implant system of claim 1 , wherein the male detachment mechanism component is configured to be attached to the female detachment mechanism component by a relative rotation between the male detachment mechanism component and the female detachment mechanism component.3. The implant system of claim 1 , wherein the male detachment mechanism component comprises an external thread configured to mate with an internal thread formed by the coil of the female detachment mechanism component.4. The implant system of claim 1 , wherein the coil is a coil spring.5. (canceled)6. The implant system of claim 1 , wherein the coil abuts the surface of the internal bore along at least a portion of the length of the coil claim 1 , and claim 1 , optionally claim 1 , wherein the coil abuts the surface of the internal bore along the entire length of the coil.7. (canceled)8. The implant system of claim 1 ...

Device and method for filling an aneurysm or body cavity

The invention relates generally to embolic agents and embolic delivery systems more specifically it relates to a device and method for filling of aneurysm or body cavity. In various embodiments, segmented and monolithic embolic agents provide the operator with the ability to select and detach the length of embolic agent, either extracorporeally or intracorporeally as desired by the operator, for implantation into the aneurysm or body cavity. Linking elements and detachment elements may be utilized by the operator to connect and detach variable lengths of embolic agents either extracorporeally or intracorporeally utilizing electrolytic, chemical, and mechanical detachment mechanisms. Embolic delivery systems are disclosed providing for constant and steady propulsion of the embolic agent.

STABLE SCREW-TYPE DETACHMENT MECHANISM

An occluding device apparatus includes an embolization coil with a distal end and a proximal end with an opening and an attacher that is threaded through the opening at the proximal end of the embolization coil. The apparatus further comprises a delivery kit for delivery of the embolization coil in a body cavity. The kit comprises a guide catheter for percutaneous introduction of the embolization coil and an inner catheter slidably disposed within the guide catheter during insertion. The inner catheter comprises a proximal end and a distal end. The inner catheter further includes a hub disposed adjacent the proximal end. The kit further comprises a guide wire slidably disposed within the inner catheter. The guide wire provides a path during insertion thereof within a body cavity. The kit further comprises a pushwire to advance the embolization coil through the inner catheter. 1. A medical device delivery assembly comprising:a medical device to be deployed, the medical device extending from a first proximal end to a first distal end, the first proximal end comprising a first interior lumen and a first outer surface, at least one prong being attached to the first outer surface of the first proximal end;a delivery portion extending from a second proximal end to a second distal end, the delivery portion comprising a second interior lumen and a second outer surface, the second interior lumen being sized so as to fit the first proximal end of the medical device to be deployed therein, the second distal end of the delivery portion comprising at least one notch for receiving the at least one prong of the medical device to be deployed; anda mandrel extending from a third proximal end to a third distal end, the mandrel being slidably disposed within the second interior lumen of the delivery portion, the third distal end of the mandrel fitting within the first interior lumen of the first proximal end of the medical device to be deployed.2. The medical device of wherein the ...

VASCULAR OCCLUSION DEVICES

Various aspects of the disclosure pertain to blood vessel occlusion devices having a central longitudinal axis and comprising: (a) a hub, (b) a self-expanding support frame comprising a plurality of wire segments forming a plurality of cells, and (c) a covering material covering cells within the transition portion. The support frame may be self-expandable from a constrained shape to an unconstrained shape that comprises (ii) a substantially cylindrical portion having a diameter and an axis that is coincident with the central longitudinal axis, the substantially cylindrical portion comprising a first ring of the cells extending in a 360° rotation around the central longitudinal axis and (ii) a transition portion disposed between the substantially cylindrical portion and the hub. Other aspects for the disclosure pertain to assemblies, kits and methods that employ such devices. 1. A blood vessel occlusion device having a central longitudinal axis and comprising: (a) a hub , (b) a self-expanding support frame comprising a plurality of wire segments forming a plurality of cells , said support frame being self-expandable from a constrained shape to an unconstrained shape that comprises (ii) a substantially cylindrical portion having a diameter and an axis that is coincident with the central longitudinal axis , said substantially cylindrical portion comprising a first ring of said cells extending in a 360° rotation around the central longitudinal axis and (ii) a transition portion disposed between the substantially cylindrical portion and the hub , and (c) a covering material covering cells within the transition portion.2. The blood vessel occlusion device of claim 1 , wherein the first ring comprises from four to eight cells.3. The blood vessel occlusion device of claim 1 , wherein the substantially cylindrical portion further comprises a second ring of said cells extending in a 360° rotation around the central longitudinal axis.4. The blood vessel occlusion device of ...

Left Atrial Appendage Occluder

A left atrial appendage occluder comprises an elastic closure disc, and a supporting structure connecting with the closure disc and being located on one side of the closure disc, with the supporting structure comprising a central end connecting with the closure disc and a plurality of interconnected and bent struts, wherein at least one anchoring thorn is set near the end of at least one strut with the anchoring thorn toward the closure disc. The left atrial appendage occluder has a stable structure, a good positioning and sealing effect on the cavity wall in the left atrial appendage, and it is easy to position repeatedly; it can also be recycled before separating from a conveyor. When in surgical operation, the left atrial appendage occluder can select the position area based on the actual shape and size of the patient's left atrial appendage, so the surgical risk is lowered. 115-. (canceled)16. A left atrial appendage occluder that is delivered to a left atrial appendage by a sheath that has a wall that defines a lumen , comprising:a closure disc;an elastic fixing frame having a distal end and a proximal end, and a central end coupled to the closure disc and provided at the proximal end of the fixing frame, wherein the distal end of the fixing frame extends outwardly from the central end and stretches out in a radial direction, and then overturns towards the proximal end to form an open end; andat least one anchor, wherein the fixing frame is located between the at least one anchor and the wall of the sheath when the fixing frame is in the sheath during delivery, and when the fixing frame is deployed outside the sheath, the anchor outwardly extends from the fixing frame.17. The occluder of claim 16 , wherein the open end of the fixing frame is adjacent to and spaced from the closure disc.18. The occluder of claim 16 , wherein the closure disc and the fixing frame both have a diameter claim 16 , and the diameter of the closure disc is larger than the diameter of ...

VASO-OCCLUSIVE DEVICES INCLUDING A FRICTION ELEMENT

Vaso-occlusive apparatuses, including implants, and methods of using them to treat aneurysms. The vaso-occlusive implants described herein include one or more soft and expandable braided member coupled to a pushable member such as a coil that maybe inserted and retrieved from within an aneurism using a delivery catheter as well as a friction element between the soft braided member and the coil. The friction element allows the relatively soft and elongate implant to be pushed out of a cannula without binding up within the cannula. 1. (canceled)2. A vaso-occlusive device adapted to be pushed through a delivery catheter and out an open distal end of the delivery catheter , the vaso-occlusive device comprising:an elongate braided tubular outer member having a radially compressed configuration when constrained within the delivery catheter, and a radially expanded configuration when pushed out the distal end of the delivery catheter so as to no longer be constrained within the delivery catheter;an elongate pushable inner member disposed within an interior of the braided tubular outer member, wherein the pushable inner member is axially moveable relative to the delivery catheter; anda friction element attached to the braided tubular outer member within the interior of the braided tubular outer member, wherein the frictional element engages the pushable inner member when the vaso-occlusive device is constrained within the delivery catheter so as to move the braided tubular outer member relative to the delivery catheter as the pushable inner member is moved relative to the delivery catheter, and wherein the friction element does not engage the pushable inner member when the vaso-occlusive device is in the radially expanded configuration.3. The vaso-occlusive device of claim 2 , wherein the pushable inner member comprises a closed pitch coil.4. The vaso-occlusive device of claim 2 , wherein the friction element is attached to the braided tubular outer member by a hinge so ...

SYSTEMS FOR VENOUS OCCLUSION FOR THE TREATMENT OF VENOUS INSUFFICIENCY

Methods, devices and systems are described for treating venous insufficiency in which the vein is compressed at least partially along a treatment zone. A system can be provided including an injection device, such as a glue gun, that is operably connected to a delivery catheter that can be advanced across a treatment zone in the vein. The delivery catheter can be used to deliver one, two, or more boluses of media (e.g., cyanoacrylate) to occlude the vein along different spaced-apart sections of the treatment zone. External compression can also be applied to the vein by a compression element, such as a hand or multifunctional ultrasound transducer, to occlude portions of the vein along the treatment zone prior to or during the introduction of the boluses of media. 120-. (canceled)21. A system for treating a vein , the system comprising:a syringe containing a vein-occluding substance;an injector for delivering the vein-occluding substance into the vein, the injector comprising a removable adapter having a first proximal end and a first distal end configured to mate with the syringe, the removable adapter defining a central lumen with openings at the first proximal end and the first distal end of the removable adapter, the injector further comprising a movable wall and an actuator configured to move the movable wall a predetermined distance within the central lumen of the removable adapter upon activation of a control, the injector being operably connectable to the control, wherein activation of the control causes the injector to deliver a bolus of between about 0.05 milliliters (mL) and 3 mL of the vein-occluding substance from the syringe into the vein, wherein the injector is configured to automatically deliver a plurality of substantially equal spaced-apart boluses of the vein-occluding substance when the actuator moves the movable wall the predetermined distance, thereby expelling the bolus of vein-occluding substance from the syringe when the syringe is mated with ...

DEVICES AND METHODS FOR DELIVERING AN ENDOCARDIAL DEVICE

Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall. 1. A method of reducing ventricular volume to treat heart disease , the method comprising:positioning an umbrella-shaped, expandable partitioning device having a reinforced membrane in a contracted configuration near the apex of a patients' ventricle using an elongate delivery catheter to which the partitioning device is releasably coupled;expanding an expansion member near the distal end of the delivery catheter to apply pressure to a proximal end region of the contracted partitioning device to expand the partitioning device; andreleasing a coupling element distal to the expansion member on the delivery catheter to deploy the partitioning device.2. The method of further comprising securing the periphery of the partitioning device to the ventricle wall.3. The method of further comprising sealing the periphery of the partitioning device to the ventricle wall.4. The method of further comprising percutaneously guiding the partitioning device on the end of the delivery catheter into the ventricle.5. The method of further comprising advancing the partitioning device into the ventricle through an inner lumen of a delivery catheter.6. The method of claim 1 , wherein the step of expanding the expansion member comprises expanding an inflatable expansion member near the distal end of the delivery catheter.7. The ...

Deployment techniques for annuloplasty ring and over-wire rotation tool

An implant structure includes a contracting mechanism, including a rotatable structure for contracting the implant structure, and a locking mechanism. A rotation tool is configured to engage and rotate the rotatable structure. A longitudinal guide member is removably coupled to the contracting mechanism, configured to guide the rotation tool to the rotatable structure, and includes a distal force applicator. The rotation tool is axially moveable with respect to the guide member. The contracting mechanism is arranged such that the locking mechanism is (a) unlocked when the guide member is coupled to the contracting mechanism in a first state, thereby allowing the rotatable structure to rotate, and (b) locked when (i) the guide member is coupled to the contracting mechanism in a second state, thereby restricting the rotation of the rotatable structure, and (ii) the guide member is not coupled to the contracting mechanism, thereby restricting the rotation of the rotatable structure.

MEDICAL DEVICE FOR MODIFICATION OF LEFT ATRIAL APPENDAGE AND RELATED SYSTEMS AND METHODS

Devices, methods and systems are provided for occluding an opening within the tissue of a body, such as a left atrial appendage. In one embodiment, a medical device includes an occluder portion and an anchor portion, the anchor portion hingably coupled to the occluder portion. With this arrangement, the anchor portion actuates and pivots relative to the occluder portion between an anchor deployed position and an anchor non-deployed position while the occluder portion is in an occluder deployed position. 1. A method for modifying a left atrial appendage of a heart , the method comprising:advancing a medical device with a catheter of a delivery system through a vasculature to the left atrial appendage of the heart in a constricted position, the medical device including a framework extending between a primary hub and a secondary hub each having a common axis;deploying the medical device adjacent the left atrial appendage to a deployed position such that, in the deployed position, the framework extends radially outward from the primary hub to extend radially toward a distal side of the framework such that, at the distal side, the framework extends radially inward to the distal end of the framework and then turns proximally and radially inward toward the secondary hub, the secondary hub remaining proximal the distal end of the framework;securing the medical device to tissue in the left atrial appendage with tissue anchors positioned on and extending from the framework proximal the distal end of the framework; andreleasing the catheter from the medical device to permanently leave the medical device in the left atrial appendage.2. The method according to claim 1 , wherein the deploying the medical device comprises deploying the medical device having a tissue growth member positioned at a proximal side of the framework.3. The method according to claim 1 , wherein the deploying the medical device comprises deploying the framework with multiple struts extending between a ...

PERCUTANEOUS CATHETER DIRECTED INTRAVASCULAR OCCLUSION DEVICES WITH RETRACTABLE STABILIZING WIRES

A medical device is provided in which one or both ends of the device encourage the formation of tissue across substantially the entire area of the respective end that is exposed to the blood flow for reducing the risk of a thrombotic embolism. The medical device further includes stabilizing wires configured to engage tissue at a target site when the medical device is in an expanded configuration and to at least partially retract into the medical device when the medical device is in a collapsed configuration. 1. A medical device configured to self-expand from a contracted state when constrained within a delivery device toward an expanded state when deployed from the delivery device for delivery to a target site within the body lumen , the medical device comprising:a tubular structure comprising a plurality of braided strands, each braided strand comprising a proximal strand end and a distal strand end, the tubular structure comprising an expanded volume portion defining an expanded volume diameter in the expanded state; anda plurality of retractable stabilizing wires that extend from the expanded volume portion in the expanded state.2. The medical device of claim 1 , wherein claim 1 , in the contracted state claim 1 , the expanded volume portion defines a contracted diameter.3. The medical device of claim 2 , wherein claim 2 , in the contracted state claim 2 , the retractable stabilizing wires are maintained at least partially within the contracted diameter of the expanded volume portion.4. The medical device of claim 3 , wherein the retractable stabilizing wires comprise a bend so as to create two interconnected stabilizing wires each having an end portion.5. The medical device of claim 4 , wherein the bend is fixedly attached to the expanded volume portion.6. The medical device of claim 4 , wherein the end portions are slidably attached to the expanded volume portion.7. The medical device of claim 6 , wherein each end portion is configured to engage tissue at a ...

FOAM OCCLUSION DEVICE

An occlusion device comprising a plurality of expandable hydrophilic foam elements is described. When the device is deployed to a body vessel or a body cavity, it expands radially due to uptake of liquid from the body fluids with which it is in contact. The device may optionally have a surrounding meshwork, an inner spring, and a screw-type deployment mechanism. A method of deploying the device is also provided. 1. A device for occlusion of a body vessel , the device comprising:a coil spring having a proximal end and a distal end, defining a longitudinal axis;a proximal collet disposed to the proximal end and a distal collet to the distal end;at least one expandable element disposed radially about a portion of the coil spring; anda covering disposed on the proximal collet about the proximal end, the covering extending from the proximal collet about the coil spring and the at least one expandable element, the covering being disposed on the distal collet about the distal end.2. The device of wherein the hydrophilic foam elements are substantially disc-shaped.3. The device of wherein the covering comprises a mesh.4. The device of further comprising a threaded capture element extending proximally from the proximal collet substantially along the longitudinal axis.5. The device of wherein the coil spring defines a lumen formed therethrough along the longitudinal axis claim 1 , each of the proximal collet and the distal collet comprising an opening formed along the longitudinal axis and in fluid communication with the lumen of the coil spring.6. The device of further comprising a tapered tip extending distally from the distal collet substantially along the longitudinal axis.7. The device of wherein the covering comprises a shape memory metal.8. The device of wherein the mesh further comprises a polyester.9. The device of wherein the shape memory metal and the polyester are present as strands claim 8 , the strands being woven together to form the mesh claim 8 , the shape ...

Devices and methods for delivering an endocardial device

Systems for partitioning a ventricle of a heart include a partitioning device or implant, and an applicator for inserting, repositioning and/or removing the partitioning device. The implant may support the ventricle wall and may reduce the volume of the ventricle. The delivery system for delivering and deploying a partitioning device into a ventricle may include a catheter having a distal coupling element for coupling to a partitioning device in a collapsed configuration; the catheter may also have an expansion member for applying force to the partitioning device to fully expand it into a deployed configuration and to secure or seal it against the ventricle wall.

RETRIEVAL WIRE CENTERING DEVICE

An occlusive implant system may include a catheter having a lumen extending therethrough, a core wire slidably and rotatably disposed within the lumen, the core wire having a threaded member disposed at a distal end, and a medical implant having an expandable frame, an occlusive element disposed on the frame, and a threaded insert coupled to a proximal portion of the frame, wherein the threaded member is removably coupled to the threaded insert. 1. An occlusive implant system , comprising:a catheter having a lumen extending therethrough;a core wire slidably and rotatably disposed within the lumen, the core wire having a threaded member disposed at a distal end thereof; anda medical implant having an expandable frame, an occlusive element disposed on the expandable frame, and a threaded insert coupled to a proximal portion of the expandable frame;wherein the threaded member is removably coupled to the threaded insert.2. The occlusive implant system of claim 1 , wherein a portion of the occlusive element is disposed between the threaded insert and the proximal portion of the expandable frame.3. The occlusive implant system of claim 1 , wherein a portion of the occlusive element extends proximally of the threaded insert.4. The occlusive implant system of claim 1 , wherein the core wire includes a guide element disposed adjacent a proximal end of the threaded member claim 1 , the guide element being configured to center the core wire within the catheter.5. The occlusive implant system of claim 4 , wherein the guide element includes a convex proximal surface and a generally flat distal surface.6. The occlusive implant system of claim 4 , wherein the guide element includes a conical proximal surface and a generally flat distal surface.7. The occlusive implant system of claim 4 , wherein the guide element includes a generally rounded convex outer surface.8. The occlusive implant system of claim 4 , wherein the guide element is disposed about the core wire.9. The occlusive ...

Multi-component vascular device

A vascular occlusion, flow restriction, shunt or filter device is disclosed comprising the assembly of at least two, of a number of selectable discrete interconnectable, interchangeable components, at least one component being of the type fabricated from metal strands braided into a tubular metal fabric having an expanded preset configuration and an elongated, collapsed reduced diameter configuration for delivery through a catheter to a treatment site and the device shaped to create an occlusion, flow restriction or shunt when placed in an opening in a body organ or vessel, the woven metal fabric having a memory property whereby the medical device tends to return to said expanded preset configuration when unconstrained.

DEVICES, SYSTEMS, AND METHODS FOR TREATING THE LEFT ATRIAL APPENDAGE

Disclosed are embodiments of a device for occluding a left atrial appendage (LAA) and other cavities or openings within a body. Some embodiments of the device can include an implant configured to be deployed within the LAA or other cavity, configured to be expanded or moved against a wall portion of the LAA or other cavity, and configured to twist at least a portion of the LAA or other cavity when the implant is rotated. Thereafter, one or more securing elements, staples, sutures, or other fasteners can be implanted in the gathered tissue to hold the tissue in the gathered state, thereby occluding the opening of the LAA or other cavity. In some embodiments, the opening of the LAA or other cavity can be occluded by elongating or otherwise reshaping the opening using an implant device, and securing the opening in the occluded state. 1. A device for treating a left atrial appendage , comprising: a contact member configured to move between a first state and a second state; and', 'a securing element;, 'an implant comprising the contact member is configured to move from the first state to the second state so that at least a portion of the contact member engages a wall portion of the left atrial appendage after the contact member has been advanced into the left atrial appendage;', 'the contact member is configured to rotate at least in a first direction from a first rotational position to a second rotational position;', 'the contact member is configured to twist at least a portion of the left atrial appendage in the first direction when the contact member is rotated from the first rotational position to the second rotational position; and', 'the securing element is configured to prevent a rotation of at least a portion of the left atrial appendage in a second direction when the securing element is in an operable state, wherein the second direction is opposite to the first direction., 'wherein2. (canceled)3. The device of claim 1 , wherein the contact member is self- ...

Lung Volume Reduction Elastic Implant and Lung Volume Reduction Instrument

Disclosed are a lung volume reduction elastic implant and a lung volume reduction device, wherein the lung volume reduction elastic implant ( 500 ) is tubular and at least opens at the proximal end thereof, and comprises an elastic deformation section ( 51 ), a flexible guide section ( 53 ) connected to the distal end of the elastic deformation section ( 51 ), and a protuberance ( 571 ) connected to the proximal end of the elastic deformation section ( 51 ), wherein the elastic deformation section ( 51 ) has shape memory characteristics and has several grooves ( 514 ) arranged at intervals along the length direction, each groove ( 514 ) connecting with the lumen of the elastic deformation section ( 51 ). Under the same external force, the flexible guide section ( 53 ) deforms more easily than the elastic deformation section ( 51 ), the outer diameter of the protuberance ( 571 ) is larger than the outer diameter of the elastic implant ( 500 ) in the delivery state when same is close to the protuberance ( 571 ), and the device delivers the implant without a delivery sheath, thereby preventing the delivery sheath from causing damage to the inner wall of the bronchus and reducing the incidence of pneumothorax.

ADJUSTABLE ANNULOPLASTY DEVICES AND ADJUSTMENT MECHANISMS THEREFOR

Apparatus is provided for adjusting at least one dimension of an implant. The apparatus includes a rotatable structure having a channel extending between first and second openings of the rotatable structure. The channel is configured for passage therethrough of an elongate tool. The rotatable structure has a lower surface that is shaped to define a first coupling. The apparatus includes a mechanical element having a surface coupled to the lower surface of the rotatable structure. The mechanical element is shaped to provide a second coupling configured to engage the first coupling during a resting state of the mechanical element, in a manner that restricts rotation of the rotatable structure. The mechanical element has a depressible portion that is disposed in communication with the second opening, and is configured to disengage the first and second couplings in response to a force applied thereto by the elongate tool. 168-. (canceled)69. Apparatus for adjusting at least one dimension of an implant , comprising: a channel extending from the first opening to the second opening, the channel being configured for passage therethrough of an elongate tool, and', 'a first coupling at the lower surface of the second end; and, 'a rotatable structure having a first end shaped to define a first opening, and a second end (a) shaped to define a second opening and (b) having a lower surface, the rotatable structure being shaped to define a second coupling configured to engage the first coupling during a resting state of the mechanical element, in a manner that restricts rotation of the rotatable structure, and', 'a depressible portion that is disposed in communication with the second opening of the lower surface of the second end of the rotatable structure, and configured to disengage the first and second couplings in response to a force applied thereto by the elongate tool., 'a mechanical element having a surface coupled to the lower surface of the second end of the rotatable ...

MEDICAL DEVICE FOR MODIFICATION OF LEFT ATRIAL APPENDAGE AND RELATED SYSTEMS AND METHODS

Devices, methods and systems are provided for occluding an opening within the tissue of a body, such as a left atrial appendage. In one embodiment, a medical device includes an anchor portion and an occluder portion. The anchor portion includes frame segments, each anchor frame segment extending between a first end and a second end such that the second end of each anchor frame segment is coupled to an anchor hub. The occluder portion includes a hub that defines an axis. The occluder portion includes multiple occluder frame segments that extend between a proximal end and a distal end such that the proximal end of the occluder frame segments are pivotably coupled to the hub and the distal end of the occluder frame segments are pivotably coupled to the first end of the anchor frame segments. 1. A medical device for modifying a left atrial appendage of a heart , the medical device comprising:an anchor portion including anchor frame segments, each anchor frame segment extending between a first end and a second end, the second end of each anchor frame segment coupled to an anchor hub; andan occluder portion including a hub defining an axis, the occluder portion including multiple occluder frame segments extending between a proximal end and a distal end, the proximal end of the occluder frame segments pivotably coupled to the hub with a first eyelet, the distal end of the occluder frame segments pivotably coupled to the first end of the anchor frame segments with a second eyelet.2. The medical device of claim 1 , wherein the anchor hub is moveable along the axis to move the anchor portion between a retracted position and a deployed position.3. The medical device of claim 1 , wherein the anchor hub is moveable along the axis to move at least a portion of the anchor portion through the hub.4. The medical device of claim 1 , wherein the occluder portion comprises a tissue growth member.5. The medical device of claim 1 , wherein the occluder portion comprises at least one of a ...

VASO-OCCLUSIVE DEVICES INCLUDING A FRICTION ELEMENT

Vaso-occlusive apparatuses, including implants, and methods of using them to treat aneurysms. The vaso-occlusive implants described herein include one or more soft and expandable braided member coupled to a pushable member such as a coil that maybe inserted and retrieved from within an aneurism using a delivery catheter as well as a friction element between the soft braided member and the coil. The friction element allows the relatively soft and elongate implant to be pushed out of a cannula without binding up within the cannula. 1. A vaso-occlusive device adapted to be pushed through a delivery catheter and out an open distal end of the delivery catheter , the vaso-occlusive device comprising:an elongate braided tubular outer member having a radially compressed configuration when constrained within the delivery catheter, and a radially expanded configuration when pushed out the distal end of the delivery catheter so as to no longer be constrained within the delivery catheter;an elongate pushable inner member disposed within an interior of the braided tubular outer member, wherein the pushable inner member is axially moveable relative to the delivery catheter; anda friction element disposed between the pushable inner member and the braided tubular outer member, wherein at least a portion of the friction element is expandable to engage an inner surface of the braided tubular outer member when the vaso-occlusive device is constrained within the delivery catheter so as to move the braided tubular outer member axially relative to the delivery catheter as the pushable inner member is moved axially relative to the delivery catheter, wherein the friction element does not engage the braided tubular outer member when the braided tubular outer member is in the radially expanded configuration.2. The vaso-occlusive device of claim 1 , wherein the friction element is coupled to the pushable inner member.3. The vaso-occlusive device of claim 2 , wherein a proximal end of the ...

CONTENT INFLATION AND DELIVERY SYSTEM

A content inflation and delivery system including a container including a fluid inlet in fluid communication with a fluid outlet; wherein the fluid outlet is positioned between the fluid inlet and a second end of the container. The system also includes an inflatable content being configured for inflation and delivery from the second end of the container. 1. A content inflation and delivery system comprising:(1) a container including (a)(i) a first end with a first end diameter and a second end with a second end diameter, (a)(ii) an inner surface and an outer surface, and (a)(iii) a vertical axis between the first end and the second end;(2) a hollow shaft including (a)(i) a first shaft end comprising a fluid inlet configured to receive a fluid and (a)(ii) a second shaft end configured to deliver the fluid;wherein the hollow shaft is movable through the container along the vertical axis;(3) a fluid outlet comprising or coupled to the second shaft end;(4) an inflatable content configured for coupling to a content inlet, wherein the content inlet has an outer surface; andwherein inflatable content is in fluid communication with the fluid outlet and the hollow shaft.2. A content inflation and delivery system of claim 1 , wherein the inflatable content comprises a first balloon and a second balloon connected by a conduit.3. The content inflation and delivery system of claim 1 , including a first container protrusion located on the inner surface of the container and a first content inlet protrusion located on the content inlet's outer surface.4. The content inflation and delivery system of claim 1 , further comprising a plurality of container protrusions located on the inner surface of the container and a plurality of content inlet protrusions located on the content inlet's outer surface;wherein the plurality of container protrusions includes a first container protrusion and a second container protrusion, and the plurality of content inlet protrusions includes a first ...

Left atrial appendage occlusion device

An occlusion device for the left atrial appendage is plastically deformable and biodegradable.

MEDICAL DEVICES FOR TREATING A TARGET SITE AND ASSOCIATED METHOD

Embodiments of the present invention provide devices and methods for treating various target sites, such as vascular abnormalities. For example, a medical device according to one embodiment includes at least one layer of a fabric of braided strands having proximal and distal ends and a central axis extending therebetween. The medical device has an expanded configuration a generally frustroconical shaped portion at each end. The medical device is configured to be constrained to a reduced configuration for delivery through a diagnostic catheter and to at least partially return, when unconstrained, towards the expanded configuration. 1. A medical device comprising:two layers of a fabric of braided strands, wherein a first layer of two layers of the fabric of braided strands comprises strands of a first diameters, and wherein a second layer of the two layers of the fabric of braided strands comprises strands of a second diameter, the medical device having proximal and distal ends and a central axis extending therebetween and having an expanded preset configuration comprising a generally frustoconical shaped portion at each end, wherein, in the expanded preset configuration, each frustoconical shaped portion comprises first and second ends and a conical portion disposed therebetween, wherein the first ends are generally planar and face one another and have a larger cross-sectional diameter than the second ends, wherein the second ends correspond to the proximal and distal ends of the medical device, wherein the medical device is configured to be constrained to a reduced configuration for delivery through a diagnostic catheter, and wherein the medical device is biased towards the expanded preset configuration such that the medical device is configured to self-expand and at least partially return, when unconstrained, towards the expanded preset configuration.2. The medical device of claim 1 , wherein the ends of the braided strands are secured from unraveling on at least ...

Temporary intraluminal filter guidewire and methods of use

The present invention is a temporary intraluminal filter guidewire for use during interventional procedures, such as angioplasty or stent deployment. A braided filter is mounted near the distal end of a steerable guidewire, which guides a therapeutic catheter. An actuator rod slides over the guidewire and is removably connected to the filter. The rod controls relative displacement of the filter ends, causing transformation of the filter between a deployed configuration and a collapsed configuration. Wire having enhanced radiopacity is included in the filter to provide visualization under fluoroscopy.

Percutaneous catheter directed intravascular occlusion devices

RETRIEVAL WIRE CENTERING DEVICE

An occlusive implant system may include a catheter having a lumen extending therethrough, a core wire slidably and rotatably disposed within the lumen, the core wire having a threaded member disposed at a distal end, and a medical implant having an expandable frame, an occlusive element disposed on the frame, and a threaded insert coupled to a proximal portion of the frame, wherein the threaded member is removably coupled to the threaded insert. 1. A medical implant , comprising:a frame configured to actuate between a collapsed configuration and an expanded configuration,wherein the expanded configuration of the frame is compliant and is configured to substantially conform to a shape and/or geometry of a lateral wall of a left atrial appendage; and to be in sealing engagement therewith when implanted in the left atrial appendage;an occlusive element configured to cover at least a proximal portion of the frame, which proximal portion spans an opening formed by the lateral wall of the left atrial appendage in the expanded configuration of the frame, and is configured to cover at least a portion of the lateral wall of the left atrial appendage distal of the opening;wherein a proximal end of the frame includes a generally tubular portion, the generally tubular portion being configured to attach to a distal end of a core wire;wherein the generally tubular portion of the frame includes a threaded insert coupledthereto,wherein a proximalmost extent of the threaded insert is substantially coplanar with a plane defined by three or more proximalmost extents of the frame in the expanded configuration,wherein the portion of the occlusive element covering the opening is substantially coplanar with the proximalmost extent of the threaded insert and the plane defined by the proximalmost extent of the frame in the expanded configuration.2. The medical implant of claim 1 , wherein the frame includes an annular collar member at least partially disposed within the generally tubular ...

System and method for delivering a left atrial appendage containment device

A device for containing emboli within a left atrial appendage of a patient includes a frame that is expandable from a reduced cross section to an enlarged cross section and a slider assembly. The frame extends between a proximal hub and a distal hub, and the slider assembly is coupled to the distal hub of the frame. The slider assembly includes a guide tube that has a channel extending proximally away from the distal hub, and a nut. The nut is longitudinally moveable within the channel of the guide tube over a predetermined distance relative to the guide tube. The nut is operable to be releasably coupled with an elongate core, and movement of the nut relative to the guide tube is at least partially limited by interference between a portion of the nut and a portion of the guide tube.

OCCLUSIVE MEDICAL DEVICE WITH FABRIC RETENTION BARB

An occlusive implant system may include a catheter having a lumen extending from a proximal opening to a distal opening, a core wire slidably disposed within the lumen, and an occlusive implant having an expandable framework configured to shift between a collapsed configuration and an expanded configuration, and an occlusive element disposed on the expandable framework. The expandable framework may include a plurality of anchor members extending radially outward from the expandable framework, at least some of the plurality of anchor members each have a barb projecting circumferentially therefrom. The occlusive implant may be releasably connected to a distal portion of the core wire. 1. An occlusive implant , comprising:an expandable framework configured to shift between a collapsed configuration and an expanded configuration that is configured to conform to and to be in a sealing engagement with a lateral wall of a left atrial appendage; andan occlusive element disposed on the expandable framework;wherein the expandable framework includes a plurality of anchor members extending radially outward from the expandable framework and extending through the occlusive element;wherein each of the plurality of anchor members includes a base attached to the expandable framework, a proximal body portion extending from the base, and a distal tip portion adapted to engage tissue;wherein at least some of the plurality of anchor members have at least one barb projecting radially and/or axially therefrom at a point distal of the base of the respective anchor member.2. The occlusive implant of claim 1 , wherein each barb projects transverse claim 1 , lateral claim 1 , and/or perpendicular to the proximal body portion.3. The occlusive implant of claim 2 , wherein each barb projects perpendicular to the proximal body portion.4. The occlusive implant of claim 1 , wherein each barb extends exterior of the occlusive element claim 1 , thereby retaining the occlusive element on the ...

LEFT ATRIAL APPENDAGE OCCLUSION DEVICES

An occlusion device () is provided for occluding a left atrial appendage (LAA), including a compliant balloon () defining a fluid-tight balloon chamber (), and an actuating shaft (), which is disposed at least partially within the balloon chamber () for setting a distance between distal and proximal end portions () of the balloon (). A proximal LAA-orifice cover () includes a frame () and a covering () fixed to the frame (). An orifice-support stent () is fixed to and extends distally from the proximal LAA-orifice cover (), and is generally cylindrical when in a radially-expanded state. Other embodiments are also described. 1. An occlusion device for occluding a left atrial appendage (LAA) , the occlusion device for use with a delivery system , the occlusion device comprising:a compliant balloon defining a fluid-tight balloon chamber;an actuating shaft, which is (a) disposed at least partially within the balloon chamber, (b) connected to a distal end portion of the balloon, and (c) longitudinally moveable with respect to a proximal end portion of the balloon so as to set a distance between the distal and the proximal end portions of the balloon;a proximal LAA-orifice cover, which (a) is configured to assume a radially-compressed state and a radially-expanded state, (b) comprises a frame and a covering fixed to the frame, and (c) when in the radially-expanded state, is generally orthogonal to the actuating shaft and has a greatest dimension, measured perpendicular to the actuating shaft, of between 10 and 50 mm; andan orifice-support stent, which (a) is fixed to and extends distally from the proximal LAA-orifice cover, (b) is configured to assume a radially-compressed state and a radially-expanded state, and (c) is generally cylindrical when in the radially-expanded state.2. The occlusion device according to claim 1 , wherein the orifice-support stent claim 1 , when in the radially-expanded state claim 1 , has (i) a greatest dimension claim 1 , measured perpendicular ...

Atrial appendage occluder for closing the left atrial appendage

The invention relates to a novel multivalent atrial appendage occluder of hybrid design based on two different atrial appendage occluders, one having a proximal disk-shaped cover and a second version without a proximal cover. The two occluder variants each provide relevant application solutions by themselves. The invention further relates to multiple specified, universal devices composed of predominantly rotationally symmetrical individual parts for producing these different LAA occluders (LAA=Left Atrial Appendage) which are graded in different sizes, for the interventional, catheter-based closure of the left atrial appendage. Axially and radially oriented hooks support the secure and gentle anchoring of the occluders 1 in the retaining area of the atrial appendage 26 . As a result, the use of substantially smaller access ports in the interventional application is possible. The two atrial appendage occluder variants, with and without proximal cover 14 , can be inserted using the same controllable access port and can be implanted in various sizes individually or in combination with one another and likewise as a hybrid variant of two occluders, one without a proximal cover ( 14 ) and one subsequently with a proximal cover ( 14 ) in one and the same atrial appendage ( 24 ) as shown in FIG. 17. The two atrial appendage occluder variants can each be released during the implantation phase in three stages until they are fully unfolded.

Cardiac stent-valve delivery system

The present invention is directed to a stent-valve for cardiac valve replacement. The stent-valve comprises a valve component and a stent component housing the valve component. The stent component and the valve component are capable of a collapsed configuration for delivery to an implantation site by a catheter and an expanded configuration after implantation. The stent-valve comprises loop material on an exterior surface of the stent component.

A cardiac stent-valve delivery system

본 발명에 따르면, 스텐트 밸브(예컨대, 단일 스텐트 밸브 및 2중 스텐트 밸브)와 최소 침습 수술을 통해 스텐트 밸브를 전달하는 관련 방법 및 시스템이 제공된다. In accordance with the present invention, there is provided a stent valve (eg, a single stent valve and a dual stent valve) and related methods and systems for delivering the stent valve through minimally invasive surgery. 판막, 대체 판막, 밸브 구성 요소, 스텐트 구성 요소, 부착 요소 Valve, Replacement Valve, Valve Component, Stent Component, Attachment Element

판막 대체를 위한 스텐트 밸브와 이와 관련된 수술을 위한 방법

본 발명에 따르면, 스텐트 밸브(예컨대, 단일 스텐트 밸브 및 2중 스텐트 밸브)와 최소 침습 수술을 통해 스텐트 밸브를 전달하는 관련 방법 및 시스템이 제공된다. 판막, 대체 판막, 밸브 구성 요소, 스텐트 구성 요소, 부착 요소

Obesity treatment devices, systems, and methods

Various devices, systems, and methods that can be used in the treatment of obesity and related illnesses are disclosed. In some instances, the cecum of an obese patient is distended to a pathophysiological size for a therapeutically effective period. The distention may be achieved by introduction of an object that is of foreign origin relative to the body of the patient into the cecum of the patient. In some instances, the distention is achieved by a medical device that transitions from an undeployed state, in which the medical device is introduced into the cecum of the patient, to an expanded state in which the medical device distends the cecum by an amount sufficient to trigger a colo-gastric brake in the patient.

Devices of intravascular occlusion guided by transcutaneous catheter

Изобретение относится к сосудистой хирургии и предназначено для окклюзии левого ушка предсердия. Устройство содержит первую часть, имеющую первый диаметр, обеспечивающий перекрытие отверстия левого ушка предсердия и выполненную с возможностью размещения поперек и снаружи левого ушка предсердия, и вторую цилиндрическую часть, имеющую второй диаметр, обеспечивающий перекрытие просвета полости, определяемой левым ушком предсердия, и выполненную с возможностью размещения, по меньшей мере, частично внутри и поперек упомянутой полости. Каждая из первой части и второй части содержат, по меньшей мере, одну плоскость окклюзии и соединены переходным сегментом, выполненным с возможностью обеспечения гибкости между первой и второй частями до 30°. Технический результат заключается в повышении гибкости и улучшении удержания внутри сосуда или полости. 14 з.п. ф-лы, 1 табл., 11 ил. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 405 473 (13) C2 (51) МПК A61B 17/08 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ, ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21), (22) Заявка: 2008151964/14, 26.12.2008 (24) Дата начала отсчета срока действия патента: 26.12.2008 (73) Патентообладатель(и): ЭйДжиЭй МЕДИКАЛ КОРПОРЕЙШН (US) (43) Дата публикации заявки: 10.07.2010 2 4 0 5 4 7 3 (45) Опубликовано: 10.12.2010 Бюл. № 34 2 4 0 5 4 7 3 R U Адрес для переписки: 129090, Москва, ул.Б.Спасская, 25, стр.3, ООО "Юридическая фирма Городисский и Партнеры", пат.пов. Ю.Д.Кузнецову (54) УСТРОЙСТВА ВНУТРИСОСУДИСТОЙ ОККЛЮЗИИ, НАПРАВЛЯЕМЫЕ ЧРЕСКОЖНЫМ КАТЕТЕРОМ предсердия, и выполненную с возможностью размещения, по меньшей мере, частично внутри и поперек упомянутой полости. Каждая из первой части и второй части содержат, по меньшей мере, одну плоскость окклюзии и соединены переходным сегментом, выполненным с возможностью обеспечения гибкости между первой и второй частями до 30°. Технический результат заключается в повышении гибкости и улучшении удержания внутри сосуда или полости. 14 з.п ...

Stent-valves for valve replacement and associated methods and systems for surgery

Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided.

Wicker OCCLUSION DEVICE WITH REPEATED EXTENDED EXTENDED VOLUME SEGMENTS SEPARATED BY COMBINED SEGMENTS

1. Устройство (100) окклюдера для окклюдирования целевого участка, содержащее:трубчатую структуру с проксимальным и дистальным концами и заранее установленной расширенной конфигурацией, причем трубчатая структура имеет отношение длины к максимальному наружному диаметру по меньшей мере примерно 4 в заранее установленной расширенной конфигурации, при этом трубчатая структура конфигурирована для сжатия до уменьшенной конфигурации для подачи на целевой участок и по меньшей мере частичного возврата к заранее установленной расширенной конфигурации внутри целевого участка, когда она не сжата, причем заранее установленная расширенная конфигурация включает множество расширенных объемных элементов (102) и сочленяющих элементов (104), расположенных повторяющимся образом, где множество расширенных элементов включает по меньшей мере один элемент в форме сферы или овалоида, с каждым сочленяющим элементом, соединяющим пару расширенных объемных элементов, и каждый расширенный объемный элемент имеет размер в сечении больше, чем размер в сечении соответствующего сочленяющего элемента, и по меньшей мере один расширенный объемный элемент имеет размер в сечении по меньшей мере такой же большой, как у целевого участка.2. Устройство (100) окклюдера по п.1, в котором расширенные объемные элементы (102) дополнительно включают по меньшей мере один диск.3. Устройство (100) окклюдера по п.1, в котором трубчатая структура содержит по меньшей мере один слой плетеной ткани.4. Устройство (100) окклюдера по п.3, в котором указанный по меньшей мере один слой плетеной ткани содержит множество плетеных прядей.5. Устройство (100) окклюдера по п.3, в которо� РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (51) МПК A61F 2/00 (13) 2011 131 863 A (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2011131863/14, 07.12.2009 (71) Заявитель(и): ЭйДжиЭй МЕДИКАЛ КОРПОРЕЙШН (US) Приоритет(ы): (30) Конвенционный приоритет: 30.12.2008 US 12/346,073 (85) Дата начала ...

Methods and devices for venous occlusion for the treatment of venous insufficiency

정맥이 치료 부위를 따라 적어도 부분적으로 압박되는, 정맥 부전을 치료하기 위한 방법, 장치 및 시스템이 기술된다. 정맥(400) 내의 치료 부위를 가로질러 전진할 수 있는 전달 카테터(202)에 작동가능하게 연결된 글루건과 같은 주입 장치(300)를 포함한, 시스템이 제공될 수 있다. 상기 전달 카테터는 상기 치료 부위의 상이한 이격 배치된 섹션을 따라 상기 정맥(400)을 폐쇄하기 위하여 매질(예를 들어, 시아노아크릴레이트)의 하나 이상의 볼러스(V2, V2')를 전달하도록 사용될 수 있다. 또한, 외부 압박이 상기 매질의 볼러스(V2, V2')를 유입시키기 전 또는 유입시키는 동안에 상기 치료 부위를 따라 상기 정맥(400)의 일부분을 폐쇄하기 위하여, 손(640) 또는 다기능 초음파 트랜스듀서(630)와 같은, 압박 요소에 의해 정맥(400)에 인가될 수 있다. A method, apparatus and system for treating venous insufficiency wherein the vein is at least partially compressed along a treatment site is described. A system may be provided that includes an infusion device 300, such as a glue gun, operatively connected to a delivery catheter 202 that is capable of advancing across a treatment site within the vein 400. The delivery catheter may be used to deliver one or more boluses (V2, V2 ') of a medium (e.g., cyanoacrylate) to close the vein (400) along a different spaced section of the treatment site . It is also contemplated that a hand 640 or multifunctional ultrasonic transducer (not shown) may be used to close a portion of the vein 400 along the treatment site prior to or during infusion of boluses V2, V2 ' May be applied to the vein (400) by a compression element, such as a clamping member (630).

Medical device for saccular aneurysm treatment

FIELD: medicine.SUBSTANCE: invention refers to medical equipment, namely to devices for treating saccular aneurysm of the vascular system. Medical device for treating saccular aneurysms comprises a metal expandable body having the possibility of long-term implantation in an artery or vein, and a node of a three-panel delivery catheter. Expandable body comprises a distal region, a proximal region generally located opposite the distal region; an intermediate region of transition from the distal region to the proximal region; a central axis extending proximally distally from the proximal region to the distal region; a wall extending, as a rule, continuously through an intermediate region from a distal region to a proximal region in order to define an external surface of the expandable body and an inner surface of the expandable body, wherein the inner surface defines a central cavity of the expandable body; and a proximal neck, a distal neck, a proximal cone-shaped tip, a distal cone-shaped tip, as well as one or more elastomer valves. Three-wide delivery catheter assembly comprises a longitudinally extending body further comprising a proximal end and a distal end generally located opposite the proximal end, wherein distal end of delivery catheter is operably connected to proximal area of expandable body; a first hollow component of the cannula which defines a first lumen which is continuous from a proximal end to a distal end and configured to receive a wire guide; a second hollow component of the cannula, which defines a second lumen to allow the passage of the fluid from the proximal end to the distal end and into the central cavity of the expandable body; and a third hollow component of the cannula, which defines a third lumen in order to allow the passage of fluid from the proximal end to the distal end and into the lumen of the blood vessel near the location of the expandable body; wherein the third hollow component of the cannula can be separated from the rest ...

MEDICAL DEVICES FOR TREATMENT OF A TARGET AREA AND THE METHOD RELATED TO THEM

1. Медицинское устройство, включающее: ! по меньшей мере, один слой ткани из плетеных нитей, имеющих проксимальные и дистальные концы, и центральную ось, проходящую между ними, причем медицинское устройство имеет расправленную предварительно установленную конфигурацию, включающую на каждом конце часть, имеющую в целом форму усеченного конуса, где каждая часть, имеющая форму усеченного конуса, включает первый и второй концы, где первые концы являются плоскостными и обращены друг к другу и имеют больший диаметр в разрезе, чем вторые концы, где вторые концы соответствуют проксимальным и дистальным концам медицинского устройства, и где медицинское устройство выполнено с возможностью принудительного сжатия в уменьшенную конфигурацию, с целью доставки через диагностический катетер и, по меньшей мере, для частичного возврата к расправленной конфигурации при устранении принудительного сжатия. ! 2. Медицинское устройство по п. 1, где указанный, по меньшей мере, один слой ткани включает плетеные первые и вторые нити, имеющие соответствующие различные первый и второй диаметры. ! 3. Медицинское устройство по п. 1, где концы плетеных нитей защищены от распутывания, по меньшей мере, на одном проксимальном и/или дистальном концах устройства. ! 4. Медицинское устройство по п. 3, дополнительно включающее пару концевых фиксаторов, фиксирующих соответствующие концы плетеных нитей и сконструированных для доставки через диагностический катетер. ! 5. Медицинское устройство по п. 4, где один из концевых фиксаторов включает резьбовую часть. ! 6. Медицинское устройство по п. 1, где ткань включает материал с памятью формы. ! 7. Медицинское � РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2010 138 602 (13) A (51) МПК A61F 2/02 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2010138602/14, 11.02.2009 (71) Заявитель(и): ЭйДжиЭй МЕДИКАЛ КОРПОРЕЙШН (US) Приоритет(ы): (30) Конвенционный приоритет: 19.02.2008 US 61/066,170 (85) Дата начала рассмотрения ...

Adjustable cingulum shaping apparatus and adjusting mechanism therefor

一种设备被提供，其包括植入结构(22，122，1122)、在其第一部分的附近区域连接至植入结构(22，122，1122)的可旋转结构(2900)和挠性件(30)。挠性件(30)的至少第一部分被布置成与可旋转结构(2900)相接触，且挠性件(30)的至少一个端部布置成不与可旋转结构(30)相接触。响应于可旋转结构(2900)沿其第一方向的旋转，挠性件(30)的前后相继部分接触可旋转结构(2900)，以将挠性件(30)的所述至少一个端部朝向植入结构(22，122，1122)的第一部分牵拉，并且相应地将植入结构(22，122，1122)的第一和第二部分朝向彼此牵引。其它应用也被描述。

Insertion and deployment catheter system for intratubal contraception

Contraceptive methods, systems, and devices generally improve the ease, speed, and reliability with which a contraceptive device can be deployed transcervically into an ostium of a fallopian tube. A distal portion of the contraceptive device can function as a guidewire. The proximal portion may remain in a small profile configuration while a sheath is withdrawn proximally, and is thereafter expanded to a large profile configuration engaging the surrounding tissues.

Devices and methods for treating vascular malformations

A system for treating a vascular malformation has an expandable device and a heating device for heating and shrinking the malformation. The expandable device may have deformable elements which plastically deform in the expanded position. The balloon may be self-expanding, balloon expanded or expanded with an actuating rod. A fluid, such as saline, may be introduced during heating when using RF heating. A sealant may also be introduced into the expandable device to further seal the aneurysm.

Occlusive coil manufacture and delivery

The present invention includes a coiled wire formed of a shape memory material for implantation into an anatomical defect. After implantation of one or more of the coiled wires according to the present invention, the defect is occluded and thereby corrected or treated. Prior to implantation, the coiled wire is generally elongated and thereafter it reverts to a predetermined shape that is suitable for occluding the defect. At least one clip having at least two prongs may be provided on the wire for attachment to body tissue. Preferably the wire is made of nickel-titanium. In an alternative embodiment, the coil includes a plurality of layers. At least one of these layers is formed of a shape memory material.

STENT WITH LAMINATED THIN FILM LINKAGE

Atrial appendage blood filtration system

Instrumentation for percutaneous delivery of blood filtration devices to atrial appendages includes a curved access sheath and a delivery tube. The curved access sheath is coursed through the patient's vasculature to gain transseptal access to a left atrial appendage. A compressed filter device attached to a tether wire is loaded in the delivery tube. The loaded delivery tube is advanced through the pre-positioned access sheath to place the device in a deployment position. The access sheath and the delivery tube can be mechanically locked and moved together to place the device in a suitable deployment position. The device is deployed by expelling it from the delivery tube either by retracting the delivery tube over the tether wire, or by moving the tether wire forward through the delivery tube. The expelled device, which is not constrained by the delivery tube walls, self expands to its useful size in the subject atrial appendage. A filter membrane in the deployed extends across the appendage ostium to filter blood flow through the ostium. The filter membrane is configured to present a flat surface to atrial blood flow past the ostium.

Retrieval wire centering device

An occlusive implant system may include a catheter having a lumen extending therethrough, a core wire slidably and rotatably disposed within the lumen, the core wire having a threaded member disposed at a distal end, and a medical implant having an expandable frame, an occlusive element disposed on the frame, and a threaded insert coupled to a proximal portion of the frame, wherein the threaded member is removably coupled to the threaded insert.

Twist-down implant delivery technologies

Medical devices and methods for delivery or implantation of tubular prostheses within hollow body organs and vessels or other luminal anatomy are disclosed. A prosthesis is held in a compressed from upon an inner wire of a delivery guide by twisting the device. The subject technologies may be used in the treatment of atherosclerosis in stenting procedures or for other purposes.

Medical devices and related systems and methods for modifying the left atrial appendage

Stent-valves for valve replacement and associated methods and systems for surgery

Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided.

Stent-valves for valve replacement and associated methods and systems for surgery

Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided.

Stent-valves for valve replacement and associated methods and systems for surgery

Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided.

Stent-valves for valve replacement and associated methods and systems for surgery

Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided.

Stent-valves for valve replacement and associated methods and systems for surgery

Stent-valves (e.g., single-stent-valves and double-stent-valves), associated methods and systems for their delivery via minimally-invasive surgery, and guide-wire compatible closure devices for sealing access orifices are provided.

MEDICAL DEVICE FOR MODIFICATION OF THE EAR OF THE LEFT ATRIAL AND THE RELATED SYSTEMS AND METHODS

А 2016114525 ко РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) 1] 3 << < < < (50) МПК Аб1В 1700 (2006.01) х п а к: м ( 1 3) А $ < © <» ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2016114525, 15.04.2016 (71) Заявитель(и): КОХИРЕКС МЕДИКАЛ, ИНК. (05) Приоритет(ы): (30) Конвенционный приоритет: (72) Автор(ы): 16.04.2015 05 62/148,317; ЭДМИСТОН Дъэрил Р. (0$), 08.04.2016 Ц 15/094,254 ДЭВИС Кларк С. (05), МАРТИН Джон Александер (05), 4 : 17.10.2017 Бюл.№2 (43) Дата публикации заявки юл. № 29 МАЙЛЗ Скотт Д. (05) Адрес для переписки: 129090, Москва, ул. Большая Спасская, д. 25, строение 3, ООО "Юридическая фирма Городисский и Партнеры" (54) МЕДИЦИНСКОЕ УСТРОЙСТВО ДЛЯ МОДИФИКАЦИИ УШКА ЛЕВОГО ПРЕДСЕРДИЯ И СООТВЕТСТВУЮЩИЕ СИСТЕМЫ И СПОСОБЫ (57) Формула изобретения 1. Медицинское устройство для модификации ушка левого предсердия сердца, содержащее участок анкера, включающий в себя сегменты каркаса анкера, причем каждый сегмент каркаса анкера проходит между первым концом и вторым концом, и второй конец каждого сегмента каркаса анкера связан со втулкой анкера; и участок окклюдера, включающий в себя втулку, образующую ось, причем участок окклюдера включает в себя множество сегментов каркаса окклюдера, проходящих между проксимальным концом и дистальным концом, при этом проксимальный конец сегментов каркаса окклюдера связан с возможностью поворота со втулкой, а дистальный конец сегментов каркаса окклюдера связан с возможностью поворота с первым концом сегментов каркаса анкера. 2. Медицинское устройство по п. 1, в котором втулка анкера выполнена с возможностью перемещения вдоль оси для перемещения участка анкера между втянутым положением и раскрытым положением. 3. Медицинское устройство по п. 1, в котором втулка анкера выполнена с возможностью перемещения вдоль оси для перемещения, по меньшей мере, части участка анкера через втулку. 4. Медицинское устройство по п. 1, в котором участок окклюдера содержит элемент для прорастания ткани. 5. Медицинское ...

DEVICE IN THE FORM OF EXTENDABLE BODY AND METHOD OF ITS APPLICATION

РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2020 115 524 A (51) МПК A61B 17/135 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2020115524, 17.09.2015 (71) Заявитель(и): МЕТЭКТИВ МЕДИКАЛ, ИНК. (US) Приоритет(ы): (30) Конвенционный приоритет: (72) Автор(ы): ФРАНАНО, Ф. Николас (US), БРУНЕЛЛ, Стефен (US), СТЕФЕНСОН, Кэтрин (US), ЛОРИ II, Говард, М. (US) (43) Дата публикации заявки: 05.06.2020 Бюл. № 16 R U (57) Формула изобретения 1. Медицинское устройство для лечения мешотчатых аневризм, содержащее: металлическое расширяемое тело, выполненное с возможностью долговременной имплантации в артерии или вене, при этом расширяемое тело содержит: дистальную область, проксимальную область, по существу, расположенную напротив дистальной области; промежуточную область перехода от дистальной области к проксимальной области; центральную ось, проходящую проксимально-дистально от проксимальной области к дистальной области; стенку, проходящую, по существу, непрерывно через промежуточную область от дистальной области к проксимальной области для с формированием наружной поверхности расширяемого тела и внутренней поверхности расширяемого тела, при этом внутренняя поверхность формирует центральную полость расширяемого тела; и проксимальную шейку, дистальную шейку, проксимальный конусообразный наконечник, дистальный конусообразный наконечник, и один или более эластомерных клапанов; узел мультипросветного катетера доставки, содержащий: проходящий в продольном направлении корпус, дополнительно содержащий проксимальный конец и дистальный конец, расположенный, по существу, напротив проксимального конца, при этом дистальный конец катетера доставки функционально присоединен к проксимальной области расширяемого тела; причем расширенное расширяемое тело выполнено с возможностью отделения от катетера доставки путем перемещения расширенного расширяемого тела и узла катетера доставки в разные стороны; при этом один или более эластомерных ...