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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 18993. Отображено 100.
05-01-2012 дата публикации

Implantable Remote Monitoring Sensor

Номер: US20120004528A1
Автор: Bing Li, Marsha A. McLaughlin, Yin Yang
Принадлежит: Alcon Research LLC

An exemplary implantable sensor includes a housing that generally conforms to a curvature of an anterior chamber of a patient's eye. A sensing device disposed in the housing is configured to detect physiological parameters and transmit a signal representing the physiological parameters. The exemplary sensor may be used to detect physiological parameters such as intraocular pressure, flow velocity of aqueous humor, blood sugar, and blood biochemicals.

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Номер записи: 1
05-01-2012 дата публикации

Ischemia detection using a heart sound sensor

Номер: US20120004565A1
Автор: Carlos Haro, Krzysztof Z. Siejko, Marina V. Brockway, Richard Fogoros, Yi Zhang, Yousufali Dalal
Принадлежит: Individual

A system comprising an implantable medical device (IMD) includes an implantable heart sound sensor to produce an electrical signal representative of at least one heart sound. The heart sound is associated with mechanical activity of a patient's heart. Additionally, the IMD includes a heart sound sensor interface circuit coupled to the heart sound sensor to produce a heart sound signal, and a signal analyzer circuit coupled to the heart sound sensor interface circuit. The signal analyzer circuit measures a baseline heart sound signal, and deems that an ischemic event has occurred using, among other things, a measured subsequent change in the heart sound signal from the established baseline heart sound signal.

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Номер записи: 2
14-03-2019 дата публикации

Устройство эндоскопической оптической когерентной томографии с коррекцией волнового фронта

Номер: RU0000187692U1
Автор: Антон Юрьевич Потлов, Сергей Владимирович Фролов
Принадлежит: Федеральное государственное бюджетное образовательное учреждение высшего образования "Тамбовский государственный технический университет" (ФГБОУ ВО "ТГТУ")

Устройство может быть использовано в медицине и ветеринарии для высокоточной диагностики в полостях и трактах организма, а также для исследований или анализа материалов. Устройство содержит плечо источника излучения, опорное плечо, плечо образца и плечо детектирования. Опорное плечо состоит из оптически связанных фокусирующей линзы опорного плеча и нейтрального фильтра. Плечо образца содержит эндоскопический зонд, фокусирующую линзу и корректор волнового фронта. Эндоскопический зонд содержит коллиматор, фокусирующую линзу эндоскопического зонда, сканирующее зеркало и волоконный жгут. Излучение коллиматора преломляется краем фокусирующей линзы и направляется на сканирующее зеркало, перенаправляющее излучение на объект и обратно через центр фокусирующей линзы на волоконный жгут. Плечо детектирования содержит блок сравнения и анализа излучения из опорного плеча и плеча образца в виде спектрометра, датчик волнового фронта и блок управления для управления корректором волнового фронта с использованием данных от датчика волнового фронта и блоком сравнения и анализа излучения. Технический результат - повышение качества изображений. 2 ил. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 187 692 U1 (51) МПК A61B 5/00 (2006.01) A61B 6/03 (2006.01) A61B 1/06 (2006.01) A61B 3/10 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ (52) СПК A61B 5/0033 (2018.08); A61B 6/03 (2018.08); A61B 1/0623 (2018.08); A61B 3/102 (2018.08) (21)(22) Заявка: 2018144097, 13.12.2018 (24) Дата начала отсчета срока действия патента: 14.03.2019 Приоритет(ы): (22) Дата подачи заявки: 13.12.2018 (45) Опубликовано: 14.03.2019 Бюл. № 8 20090043211 A1, 12.02.2009. US 2014218684 A1, 07.08.2014. CN 105640480 A, 08.06.2016. RU 184084 U1, 15.10.2018. (54) Устройство эндоскопической оптической когерентной томографии с коррекцией волнового фронта (57) Реферат: Устройство может быть использовано в и волоконный жгут. Излучение коллиматора медицине и ветеринарии для ...

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Номер записи: 3
12-01-2012 дата публикации

Compartment Syndrome Monitoring Systems and Methods

Номер: US20120010525A1
Автор: David J. Jacofsky, John P. Peeters, Marc C. Jacofsky
Принадлежит: TCI3 Pressure Applications LLC

Embodiments of a compartment monitor that can be implanted and left in situ to continuously (or semi-continuously) measure compartment pressures are presented. An exemplary monitor includes a pressure sensor adapted to be implanted in a compartment, a transmitter external to the compartment and coupled to the pressure sensor, and a receiver in communication with the transmitter to receive and process pressure data received from the transmitter. The monitor may also be configured to transmit measured pressure data to a networkable device. The networkable device can then communicate the patient's status and condition to a healthcare provider through a local area network (LAN) or wide area network (WAN). This communication allows the healthcare provider to remotely monitor a patient. The networkable device, or associated computing system, can record and display trends in the pressure data over time, and log the data to the patient's electronic health records.

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Номер записи: 4
19-01-2012 дата публикации

High-throughput production of ingestible event markers

Номер: US20120011699A1
Автор: Benedict J. Costello, Eric Snyder, Gregory Moon, Hooman Hafezi, Kityee Au-Yeung, Maria Casillas Holen, Mark Zdeblick, Mauro Folena, Pratish Rao, Robert Duck, Timothy Robertson
Принадлежит: Proteus Biomedical Inc

High-throughput ingestible event marker manufacturing systems are provided. The systems include an assembly unit configured to stably associate an ingestible event marker with a carrier to produce a product. Also provided are manufacturing methods to produce such products which include assembling an ingestible event marker with an assembly unit configured to stably associate an ingestible event marker with a carrier.

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Номер записи: 5
19-01-2012 дата публикации

System, apparatus, and method for in-vivo assessment of relative position of an implant

Номер: US20120016228A1
Автор: Christophe Courcimault, Florent Cros, Jason Kroh
Принадлежит: CardioMEMS LLC

A method for providing an in-vivo assessment of relative movement of an implant that is positioned in a living being is provided that comprises a first assembly and a second assembly that are positioned within the living being. The first assembly comprises a passive electrical resonant circuit that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and, in response to the electromagnetic coupling, generates an output signal characterized by a frequency that is dependent upon a distance between the first assembly and the second assembly at the time of the electromagnetic coupling.

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Номер записи: 6
02-02-2012 дата публикации

Antenna For An Implantable Medical Device

Номер: US20120029323A1
Автор: Yanzhu Zhao
Принадлежит: MEDTRONIC INC

This disclosure describes antenna structures for use in an implantable medical device. The antenna structure may include an inner portion that is magnetically coupled to an outer portion. In one example, the inner and outer portions comprise conductive loops. In accordance with the techniques of this disclosure, a capacitive sensor is electrically coupled to one of the conductive loops of the antenna of the implantable medical device. As the capacitance of the capacitive sensor changes as a function of the sensed parameter, an impedance of the antenna varies with the output of the capacitive sensor. This variation in impedance of the antenna modulates a carrier signal with the measured parameter. In other words, the measured parameter is modulated onto the carrier signal as a change in amplitude caused by variation in impedance of antenna during radiation/transmission.

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Номер записи: 7
02-02-2012 дата публикации

Antenna For An Implantable Medical Device

Номер: US20120029598A1
Автор: Yanzhu Zhao
Принадлежит: MEDTRONIC INC

This disclosure describes antenna structures for use in an implantable medical device. The implantable medical device may include a housing that hermetically encloses electronic components of the implantable medical device and a fixation mechanism that affixes the implantable medical device to a target location, such as a wall of a vessel. The fixation mechanism functions as a radiating element of an antenna of the implantable medical device. The housing of the implantable medical device may include a conductive loop that electrically couples to a telemetry module and magnetically couples to the fixation mechanism. The telemetry module may provide signals to be transmitted to the inner loop and those signals are magnetically coupled between the inner loop and the fixation mechanism, which radiates the signals.

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Номер записи: 8
16-02-2012 дата публикации

Devices and methods for respiratory variation monitoring by measurement of respiratory volumes, motion and variability

Номер: US20120041279A1
Автор: Alexander Mattfolk, Alexander Panasyuk, Anita Karcz, Arvil Nagpal, Charles Jahnke, James F. Toy, IV, Jenny E. Freeman, Michael Lalli, Nathaniel Steiger, Roman Bokhenik, Svetlana V. Panasyuk
Принадлежит: Respiratory Motion Inc

This invention is directed to devices and methods for assessing a patient. The devices have at least one impedance measuring element functionally connected to a programmable element, programmed to analyze an impedance measurement, and to provide an assessment of at least one respiratory parameter of the patient. Preferably the device includes electronics which aid in calibration, signal acquisition, conditioning, and filtering.

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Номер записи: 9
16-02-2012 дата публикации

Apparatus, System and Method for Ultrasound Powered Neurotelemetry

Номер: US20120041310A1
Автор: Bruce C. Towe
Принадлежит: Arizona Board of Regents of ASU

The present embodiments provide an apparatus, system, and method for ultrasound powered neurotelemetry. In one embodiment, the apparatus includes a piezoelectric element configured to receive an ultrasonic pulse and convert the electronic pulse into an electric potential. A diode may be coupled to the piezoelectric element, the diode configured to cause an electric current to flow in response to the electric potential. The apparatus may additionally include a reference electrode and a stimulating electrode coupled to the diode. The reference electrode may sense bioelectric activity in a region of body tissue located in proximity to the reference diode. The stimulating electrode may emit a carrier signal, wherein the carrier signal is modulated in response to the bioelectric activity sensed by the reference electrode.

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Номер записи: 10
01-03-2012 дата публикации

Method and System For Patient-Specific Modeling of Blood Flow

Номер: US20120053921A1
Автор: Charles A. Taylor
Принадлежит: HeartFlow Inc

Embodiments include a system for planning treatment for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of an anatomical structure of the patient, create a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data, and determine a first fractional flow reserve within the anatomical structure of the patient based on the three-dimensional model and information regarding a physiological condition of the patient. The at least one computer system may be further configured to receive input from a user regarding a plan of treatment, modify the physiological condition of the patient based on the received input, and determine a second fractional flow reserve within the anatomical structure of the patient based on the modified physiological condition of the patient.

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Номер записи: 11
08-03-2012 дата публикации

Hybrid MR/PET Scanner With Patient Table Split Cable Feed

Номер: US20120059242A1
Автор: Elmar Rummert, James Frank Caruba, Ralf Ladebeck
Принадлежит: SIEMENS AG, Siemens Medical Solutions USA Inc

A hybrid magnetic resonance (MR) and positron emission tomography (PET) imaging system reduces likelihood of artifact distortion in PET images attributable to MR local coil cables and connectors in the patient table. MR local coil cables coupling the MR scanner and the MR local coil connectors are oriented so that they are outside the scanner field of view when performing PET scans.

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Номер записи: 12
08-03-2012 дата публикации

Method and device for monitoring and improving arteriogenesis

Номер: US20120059245A1
Автор: Axel Pries, Ferdinand Lenoble, Ivo Buschmann
Принадлежит: Charite Universitaetsmedizin Berlin

A method for determining an arteriovascular condition of a subject having an arterial blood flow is shown. The method involves determining a temporal progression of an instantaneous blood flow condition of the arterial blood flow as well as deriving a slew rate of the temporal progression during an increase of the temporal progression. In addition, an arteriovascular condition indicator device is shown, which comprises: an input for receiving an input signal representing an instantaneous arterial blood flow condition of a subject and a slew rate monitor connected to the input. A corresponding control device for providing an activation signal is also shown. The control device comprises a maximum detector connected to the slew rate monitor. A method for stimulation of arteriogenesis is also shown, wherein a temporal progression of an instantaneous blood flow condition is monitored, a slew rate of the temporal progression is derived, and the maximum of the slew rate is determined. An external pressure is applied repeatedly to the arteriovascular section in synchronization with the occurrence of the determined maximum.

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Номер записи: 13
29-03-2012 дата публикации

Phantom Identification

Номер: US20120076371A1
Автор: James Frank Caruba, Ralf Ladebeck
Принадлежит: SIEMENS AG, Siemens Medical Solutions USA Inc

The invention relates to calibration phantoms used in connection with medical imaging devices such as PET, MR, etc., and particularly in connection with hybrid systems such as MR/PET systems. In some cases, the phantoms have distinguishable, machine-readable identification features that allow the imaging system to identify them automatically, without operator intervention. In other cases, even where the phantoms do not have such distinguishable, machine-readable identification features, if the imaging system is appropriately configured with cameras and/or appropriate image analysis software, the imaging system can still identify the phantoms automatically.

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Номер записи: 14
29-03-2012 дата публикации

Apparatus And Methods For Wireless Communication Via Electrical Pulses Conducted By The Interstitial Tissues Of The Body For An Active Implantable Medical Device

Номер: US20120078322A1
Автор: Ashutosh Ghidiyal, Renzo Dal Molin
Принадлежит: SORIN CRM SAS

An active implantable medical device having wireless communication of data via electrical pulses conducted by the interstitial tissues of the body. This device ( 12, 14 ) includes a pair of electrodes ( 22, 24 ) and generates pulse trains consisting of a series of electrical pulses applied to the electrodes. The pulse train is modulated by digital information (data) that is produced by the device. A regulated current or voltage source ( 42 ) is used to generate ( 44, 48 ) current or voltage pulses to form the pulse train. Each current or voltage pulse is a biphasic pulse comprising a positive and negative alternation. The biphasic current or voltage modulated by the digital information, is injected between the electrodes ( 22, 24 ) and wirelessly communicated.

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Номер записи: 15
12-04-2012 дата публикации

Multi-Modal Medical Imaging and Type Detection

Номер: US20120089005A1
Автор: Ghobad Heidari-Bateni, Rahim Bagheri
Принадлежит: WiLinx Corp

A multi-modal medical imaging and type detection have been described have been disclosed. By combining a broadband radio imaging system and one or more other modalities of image processing an enhanced image and/or tissue classification can be produced.

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Номер записи: 16
03-05-2012 дата публикации

Magnetic resonance imaging apparatus and magnetic resonance imaging method

Номер: US20120108946A1
Автор: Shigehide Kuhara
Принадлежит: Individual

According to one embodiment, a MRI apparatus includes an acquisition unit, a reference section information calculating unit, a positioning unit and an imaging unit. The acquisition unit acquires frames of section image data including a heart from an object with use of magnetic resonance. The reference section information calculating unit calculates spatial positional information of a reference section of the heart based on the frames of the section image data. The positioning unit displays a reference section image of the heart on a display unit and performs positioning of an imaging part for imaging through the displayed reference section image of the heart. The reference section image is calculated from the frames of the section image data based on the positional information of the reference section. The imaging unit images the imaging part set by the positioning.

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Номер записи: 17
17-05-2012 дата публикации

Arrangement and method for influencing and/or detecting magnetic particles and for magnetic resonance imaging

Номер: US20120119739A1
Автор: Bernhard Gleich
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS NV

Magnetic particle imaging allows the imaging of fast tracer dynamics, but there is no native tissue contrast. A combination with MRI solves this issue. However, coil geometries in MPI and MRI differ significantly, making direct use impractical. According to one aspect of the present invention it is proposed to use pre-polarized MRI to overcome these difficulties. Further, methods and arrangements are proposed to achieve MRI imaging with minimal additional hardware.

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Номер записи: 18
17-05-2012 дата публикации

Real-time self-calibrating sensor system and method

Номер: US20120123690A1
Автор: Barry Keenan, LU Wang, Rajiv Shah, Wayne A. Morgan
Принадлежит: Medtronic Minimed Inc

A system and method for calibrating a sensor of a characteristic monitoring system in real time utilizes a self-calibration module for periodic determination of, and compensation for, the IR drop across unwanted resistances in a cell. A current-interrupt switch is used to open the self-calibration module circuit and either measure the IR drop using a high-frequency (MHz) ADC module, or estimate it through linear regression of acquired samples of the voltage across the sensor's working and reference electrodes (Vmeasured) over time. The IR drop is then subtracted from the closed-circuit value of Vmeasured to calculate the overpotential that exists in the cell (Vimportant). Vimportant may be further optimized by subtracting the value of the open-circuit voltage (Voc) across the sensor's working and reference electrodes. The values of Vmeasured and Vimportant are then controlled by respective first and second control units to compensate for the IR drop.

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Номер записи: 19
24-05-2012 дата публикации

Non-Invasive Measurement Of Fluid Pressure In An Adjustable Gastric Band

Номер: US20120130273A1
Автор: Lauren S. Perry, Russell L. Holscher, William L. Hassler, Jr.
Принадлежит: Ethicon Endo Surgery Inc

A food intake restriction device for forming a restriction in a patient's gastro-intestinal tract and non-invasively communicating pressure data regarding the restriction to an external monitor. The device includes a food intake restriction device implanted substantially about a patient's gastro-intestinal tract to form a restricted opening in the tract. A port is connected to the restriction device. The port contains a working fluid for affecting the size of the restricted opening. A pressure sensing system communicates with the working fluid to measure the pressure of the working fluid. A transmitter communicates the measured fluid pressure to the external monitor.

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Номер записи: 20
24-05-2012 дата публикации

Folded antennas for implantable medical devices

Номер: US20120130451A1
Автор: David A. Chizek, Dennis E. Larson, John M. Edgell, Keith R. Maile, Sasidhar Vajha
Принадлежит: Cardiac Pacemakers Inc

Subject matter such as a method or apparatus can include an implantable medical device comprising a housing, an implantable telemetry circuit carried within the housing, and a dielectric compartment, mechanically coupled to the housing an implantable telemetry antenna, such as located at least partially within the dielectric compartment. The implantable telemetry circuit can be electrically coupled to the implantable telemetry antenna and configured to wirelessly transfer information electromagnetically using the implantable telemetry antenna. The implantable telemetry antenna can include a spiral conductor portion extending along a face portion of the dielectric compartment, and a loading portion configured to adjust an input impedance of the implantable telemetry antenna, to provide a specified input impedance range within a specified range of operating frequencies to be used for wireless information transfer.

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Номер записи: 21
21-06-2012 дата публикации

Transcutaneous energy transfer system with vibration inducing warning circuitry

Номер: US20120154143A1
Автор: Ralph L. D'Ambrosio
Принадлежит: Abiomed Inc

An improved alarm device for use in a transcutaneous energy transfer (TET) system is provided. The device includes a processor configured to monitor at least one function of an implanted cardiac assist device and to generate an internal vibratory alarm.

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Номер записи: 22
05-07-2012 дата публикации

Reagents and methods for modulating cone photoreceptor activity

Номер: US20120172419A1
Автор: James A. Kuchenbecker, Jay Neitz, Maureen Neitz
Принадлежит: Medical College of Wisconsin Research Foundation Inc, UNIVERSITY OF WASHINGTON

The present invention provides reagents and methods for modulating cone photoreceptor activity, and devices for assessment of cone photoreceptor activity.

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Номер записи: 23
05-07-2012 дата публикации

Open Architecture Imaging Apparatus and Coil System for Magnetic Resonance Imaging

Номер: US20120172704A1
Автор: Cameron Anthony Piron, Christopher Alexander Luginbuhl, Donald B. Plewes
Принадлежит: Hologic Inc

Apparatus and method for using radio frequency coil systems for magnetic resonance imaging within an open architecture apparatus is provided. The MRI coil system includes a support structure with an open architecture in which secondary support structures, compression systems and plates containing RF coil systems may be introduced. These structures and RF coils can be moved relative to the patient, or removed entirely from the system. In one embodiment the system consists of a tabletop coil system, while another embodiment consists of a dedicated stretcher design.

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Номер записи: 24
12-07-2012 дата публикации

Ct and mri synchronous detection positioning needle

Номер: US20120179025A1
Автор: Dedong Ma, Hongxiu Lu, Qingshi Zeng, Wei Xiao, Ying Xing
Принадлежит: Shandong University

Disclosed is a CT and MRI synchronous detection positioning needle. The needle comprises a silicone tube which is internally provided with a guide needle; the two sides of the guide needle are provided with hollow cavities; each hollow cavity is internally provided with membranes dividing the hollow cavity into a plurality of small chambers which are filled with liquid, wherein a CT contrast agent is filled in a plurality of small chambers at one side of the guide needle, and an MRI contrast agent is filled in a plurality of small chambers at the other side of the guide needle. In the invention, specially designed silicone positioning needles are implanted in vivo, and synchronous comparison of different image data and pathological data is implemented by means of multi-plane reconstruction technology, so the CT and MRI synchronous detection positioning needle can be widely applied to experimental study on tumors.

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Номер записи: 25
09-08-2012 дата публикации

Transceiver unit in a measurement system

Номер: US20120203118A1
Автор: Magnus Samuelsson, Sauli Tulkki
Принадлежит: St Jude Medical Systems Ab

A measurement system may comprise a sensor wire and a transceiver unit. The sensor wire may comprise an insertable portion configured to be inserted in a blood vessel of a patient's body and a sensor disposed within the insertable portion at a distal end of the sensor wire. The sensor is configured to measure a parameter when inserted inside the patient. The transceiver unit may comprise: a housing adapted to be connected to a proximal end of the sensor wire; and a first communication module within the housing adapted to wirelessly communicate by a communication signal with an external second communication module in order to transfer information to the external second communication module.

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Номер записи: 26
16-08-2012 дата публикации

Pet/mr scanners for simultaneous pet and mr imaging

Номер: US20120206139A1
Автор: Andreas Thon, Johan Overweg, Torsten Solf, Volkmar Schulz
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS NV

In a combined system, a magnetic resonance (MR) scanner includes a magnet configured to generate a static magnetic field at least in a MR examination region from which MR data are acquired. Radiation detectors are configured to detect gamma rays generated by positron-electron annihilation events in a positron emission tomography (PET) examination region. The radiation detectors include electron multiplier elements having a direction of electron acceleration arranged substantially parallel or anti-parallel with the static magnetic field. In some embodiments, the magnet is an open magnet having first and second spaced apart magnet pole pieces disposed on opposite sides of a magnetic resonance examination region, and the radiation detectors include first and second arrays of radiation detectors disposed with the first and second spaced apart magnet pole pieces.

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Номер записи: 27
16-08-2012 дата публикации

System and method for interactive three dimensional operation guidance system for soft organs based on anatomic map

Номер: US20120209106A1
Автор: Changbo Yang, Cheng-Chung Liang, Guo-Qing Wei, Jian-Zhong Qian, Li Fan, Xiaolan Zeng, Xin Dou
Принадлежит: EDDA Tech (SUZHOU) Ltd, EDDA Technology Inc

A system for providing visual three dimensional assistance to a user during a medical procedure involving a soft organ. The system and method provide visual assistance to a user during a medical procedure involving a soft organ. The system and method utilize a processor for generating an image of the soft organ, a surgical instrument tracker for tracking a surgical instrument during the medical procedure, and a display in communication with the processor and the surgical instrument tracker for visually displaying in three dimensions, the image of the soft organ and the surgical instrument in relation to the soft organ.

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Номер записи: 28
16-08-2012 дата публикации

Apparatus and method for outputting heart sounds

Номер: US20120209130A1
Автор: Arthur L. Olive, Avram Scheiner, Don Villalta, Qingsheng Zhu
Принадлежит: Individual

An apparatus for outputting heart sounds includes an implantable system and an external system. The implantable system includes a sensor for generating sensed signals representing detected heart sounds, an interface circuit and a control circuit for receiving the sensed signals, generating data representing the heart sounds therefrom, and transmitting the data to the external system via the interface circuit. The external system includes an interface circuit for communicating with the implantable system, and a control circuit for receiving the data representing the heart sounds and for generating control signals that cause an output device to generate outputs representing the sounds. The implantable system may also include a sensor(s) for detecting cardiac electrical signals. In this case, outputs representing the cardiac electrical signals are also output.

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Номер записи: 29
16-08-2012 дата публикации

Method and apparatus of acoustic communication for implantable medical device

Номер: US20120209342A1
Автор: Abhi Chavan, Jeffrey A. Von Arx, Scott T. Mazar
Принадлежит: Individual

An implantable medical device includes an acoustic transducer for intra-body communication with another medical device via an acoustic couple. The acoustic transducer includes one or more piezoelectric transducers. In one embodiment, an implantable medical device housing contains a cardiac rhythm management (CRM) device and an acoustic communication circuit. The acoustic transducer is electrically connected to the acoustic communication circuit to function as an acoustic coupler and physically fastened to a wall of the implantable housing, directly or via a supporting structure.

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Номер записи: 30
23-08-2012 дата публикации

Implantable systems and methods for use therewith for monitoring and modifying arterial blood pressure without requiring an intravascular pressure transducer

Номер: US20120215275A1
Автор: Allen Keel, Brian Jeffrey Wenzel, Edward Karst, Jong Gill, Michael E. Benser, Taraneh Ghaffari Farazi, Timothy A. Fayram, Wenbo Hou
Принадлежит: Pacesetter Inc

Embodiments of the present invention are directed to implantable systems, and methods for use therewith, that monitor and modify a patient's arterial blood pressure without requiring an intravascular pressure transducer. In accordance with an embodiment, for each of a plurality of periods of time, there is a determination one or more metrics indicative of pulse arrival time (PAT), each of which are indicative of how long it takes for the left ventricle to generate a pressure pulsation that travels from the patient's aorta to a location remote from the patient's aorta. Based on the one or more metrics indicative of PAT, the patient's arterial blood pressure is estimated. Changes in the arterial blood pressure are monitored over time. Additionally, the patient's arterial blood pressure can be modified by initiating and/or adjusting pacing and/or other therapy based on the estimates of the patient's arterial blood pressure and/or monitored changes therein.

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Номер записи: 31
30-08-2012 дата публикации

Method and Apparatus for Measuring Blood Volume

Номер: US20120220886A1
Автор: Kim Wood, P. Chad Hodgson, Peter Plouf
Принадлежит: Individual

In one aspect, a conductance catheter is provided for measuring the volume of a fluid. The conductance catheter comprises a series of electrodes and a circuit to compensate for variations in sensitivity of the electrodes in the catheter. In another aspect, a resistivity sensor is provided for determining the resistivity of a fluid. The sensor comprises a series of electrodes spaced such that the total distance between endmost electrodes does not exceed the diameter of the catheter deploying the sensor.

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Номер записи: 32
06-09-2012 дата публикации

Systems and methods for remote monitoring of signals sensed by an implantable medical device during an mri

Номер: US20120226140A1
Автор: Gabriel A. Mouchawar, Xiaoyi Min
Принадлежит: Pacesetter Inc

Systems and methods are provided for allowing an implantable medical device, such as pacemaker, to properly sense electrophysiological signals and hemodynamic signals within a patient during a magnetic resonance imaging (MRI) procedure. Systems and methods are also provided for allowing the implantable medical device to transmit the sensed data to an external monitoring system during the MRI procedure so that attending medical personnel can closely monitor the health of the patient and the operation of the implantable device during the MRI. These improvements provide the attending personnel with information needed to determine whether the MRI should be suspended in response to induced tachyarrhythmias or other adverse conditions within the patient.

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Номер записи: 33
04-10-2012 дата публикации

Image recording device for the simultaneous recording of magnetic resonance image data and nuclear medical image data

Номер: US20120253174A1
Автор: Stefan Popescu
Принадлежит: SIEMENS AG

An image recording device is disclosed for the simultaneous recording of magnetic resonance image data and nuclear medical image data, in particular PET image data. In at least one embodiment, the image recording device includes a nuclear medical detector arrangement integrated into a magnetic resonance device, wherein a fluorescence detector arrangement including an optical system and designed for fluorescence imaging is also integrated into the magnetic resonance device.

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Номер записи: 34
04-10-2012 дата публикации

Device and method to measure bone healing

Номер: US20120253345A1
Автор: John J. Wixted
Принадлежит: University of Massachusetts UMass

Advances in our understanding of the cellular mechanisms underlying skeletal regeneration have not been effectively translated in vivo treatment because non-invasive monitoring of bone fracture healing is limited to imaging technology (i.e., for example, x-rays) that cannot be quantified and are subjectively interpreted. The method disclosed herein assesses rates of hip fracture healing using a strain gauge device implanted into a standard orthopedic implant. It has been demonstrated that such a device can measure differences between intact and partially osteotomized fracture models (p<0.05) and that the device can distinguish between stable and unstable fracture patterns in completely osteotomized models across a physiologic range of loads. Such devices are compatible with in vivo bone fracture healing methods, wherein the device is placed onto an orthopedic implant and the strain data is transmitted on a real time basis, thereby providing a non-invasive quantification of bone fracture repair rates.

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Номер записи: 35
18-10-2012 дата публикации

Advanced analyte sensor calibration and error detection

Номер: US20120265037A1
Автор: Daiting Rong, Peter C. Simpson, Sebastian Böhm
Принадлежит: Dexcom Inc

Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

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Номер записи: 36
01-11-2012 дата публикации

Inductively rechargeable implantable device with reduced eddy currents

Номер: US20120274271A1
Автор: Anthony W. Cowley, David L. Thompson, Eric Y. Chow, James L. Flesher, Jared B. Floyd, Jianxiang Shen, Saadat Hussain
Принадлежит: Cyberonics Inc

A case for an implantable medical device includes a metal case portion, having an inside and an outside, configured to attach to at least one other case portion to define a biocompatible case for the implantable medical device. The metal case portion has a plurality of grooves disposed on at least one of the inside and the outside, the grooves being oriented substantially perpendicular to an expected direction of eddy currents produced by an inductive recharging coil in proximity thereto.

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Номер записи: 37
01-11-2012 дата публикации

Predictive background data transfer for implantable medical devices

Номер: US20120278760A1
Автор: Douglas S. Cerny, Kevin L. Bright, Reginald J. Warren, Van L. Snyder
Принадлежит: MEDTRONIC INC

Data is transferred from an implantable medical device (IMD) to one or more external devices passively in the background of an active communications session based on a prediction of data that will be requested by a user.

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Номер записи: 38
08-11-2012 дата публикации

System and method for reconstructing cardiac activation information

Номер: US20120283579A1
Автор: Carey Robert Briggs, Sanjiv Narayan
Принадлежит: Topera Inc, UNIVERSITY OF CALIFORNIA

An example system and method of reconstructing biological activation information are disclosed. A first biological signal and a second biological signal associated with an organ are processed via a computing device to determine whether there is a point of change in a derivative of the first biological signal with respect to a derivative of the second biological signal above a threshold. An activation onset time is assigned in the first biological signal at the point of change to define biological activation associated with the organ in the first cardiac signal if it is determined that the point of change is above the threshold.

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Номер записи: 39
22-11-2012 дата публикации

Phrenic nerve stimulation detection using heart sounds

Номер: US20120296387A1
Автор: Jeffrey M. Gillberg, Paul J. Degroot, Thomas J. Mullen, Xusheng Zhang
Принадлежит: Massachusetts Institute of Technology, MEDTRONIC INC

A method of delivering phrenic nerve stimulation in a medical device system that includes detecting an activation event, delivering phrenic nerve stimulation therapy in response to the detected activation event, sensing a heart sound signal, in response to the delivered phrenic nerve stimulation therapy, monitoring a portion of the sensed heart sound signal, the portion defined by a predetermined window ocurring after the delivered phrenic nerve stimulation therapy, and determining whether the delivered phrenic nerve stimulation therapy was successful in response to the monitoring.

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Номер записи: 40
22-11-2012 дата публикации

Phrenic nerve stimulation detection using heart sounds

Номер: US20120296388A1
Автор: Jeffrey M. Gillberg, Paul J. Degroot, Thomas J. Mullen, Xusheng Zhang
Принадлежит: MEDTRONIC INC

A method and system of detecting phrenic nerve stimulation in a patient that includes detecting an activation event, obtaining a heart sound signal of a patient from an implanted heart sound sensor, determining that an electrical stimulation has been applied to the patient, in response to detecting the activation event, monitoring a portion of the heart sound signal, the portion defined by a predetermined window after the application of the electrical stimulation, and determining whether phrenic nerve stimulation occurred based on the portion of the heart sound signal.

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Номер записи: 41
22-11-2012 дата публикации

Array of Joined Microtransponders for Implantation

Номер: US20120296399A1
Автор: Lawrence Cauller, Richard Weiner
Принадлежит: Microtransponder Inc, University of Texas System

A wireless microtransponder array constructed as a single structure of joined microtransponders. The microtransponders can be configured as a linear array strip with connective material in between. The microtransponders can also be entirely embedded within a strip of material, or joined by a single, common substrate structure.

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Номер записи: 42
29-11-2012 дата публикации

System and method for specificity-based multimodality three- dimensional optical tomography imaging

Номер: US20120302880A1
Автор: Chenghu Qin, DONG Han, Jie TIAN, Kai Liu, XIN YANG
Принадлежит: Shenyang Institute of Automation of CAS

A system and method for specificity-based multimodality three-dimensional optical tomography imaging comprises steps of: optical imaging to obtain a light intensity of body surface optical signal of an imaging target; CT imaging to obtain structure volume data; establishing an equation representing a linear relationship between the distribution of the obtained light intensity of body surface optical signal of the imaging target, the obtained CT discrete mesh data and the distribution of unknown internal self-luminescence light sources; establishing a dynamic sparse regularization target function in every iteration for the equation; and reconstructing a tomography image. The present invention well considers the optical specificity of tissue, in which there is a non-uniform optical characteristic parameter distribution within the same tissue when finite element modeling is used, which is closer to the real situation, so that an accurate imaging effect is achieved.

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Номер записи: 43
13-12-2012 дата публикации

Image guided high intensity focused ultrasound treatment of nerves

Номер: US20120316426A1
Автор: James W. Little, Jessica L. Foley, Shahram Vaezy
Принадлежит: UNIVERSITY OF WASHINGTON

A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures.

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Номер записи: 44
27-12-2012 дата публикации

Pet-mri convergence system

Номер: US20120330128A1
Автор: Hyun-Wook Park, Myung-Sung Song
Принадлежит: Korea Advanced Institute of Science and Technology KAIST

A Positron Emission Tomography (PET)-Magnetic Resonance Imaging (MRI) convergence system may be provided that includes: a magnet bore having a cylindrical shape, an outer wall and an inner wall; a gradient coil disposed to contact with the inner wall of the magnet bore; a body coil which is disposed to contact with the inner wall of the gradient coil, emits an RF pulse signal, and has a first through-hole formed therein; and an MRI RF receiving coil detecting MRI data corresponding to the RF pulse signal. The PET detector includes a second through-hole formed therein and contacts with one end of the body coil such that the first through-hole is connected to the second through-hole. The examinee transporter is transportable through the first through-hole and the second through-hole.

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Номер записи: 45
31-01-2013 дата публикации

Method and apparatus for medical imaging using near-infrared optical tomography and flourescence tomography combined with ultrasound

Номер: US20130030289A1
Автор: Baohong Yuan, Quing Zhu
Принадлежит: University of Connecticut

Methods and apparatus for medical imaging using diffusive optical tomography and fluorescent diffusive optical tomography are disclosed. In one embodiment, a method for medical imaging comprises, scanning a tissue volume with near-infrared light to obtain structural parameters, wherein the tissue volume includes a biological entity, scanning the tissue volume with near-infrared light to obtain optical and fluorescence measurements of the scanned volume, segmenting the scanned volume into a first region and a second region, and reconstructing an optical image and a fluorescence image of at least a portion of the scanned volume from the structural parameters and the optical and fluorescence measurements. In another embodiment an apparatus for medical imaging is disclosed.

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Номер записи: 46
31-01-2013 дата публикации

Devices and methods for treatment of heart failure and associated conditions

Номер: US20130030309A1
Автор: Dimitrios Georgakopoulos, Eric Grant Lovett, Nadim Yared
Принадлежит: CVRX Inc

Devices and methods of use for identification, treatment, and/or management of heart failure and/or associated conditions. Methods may include providing a baroreflex therapy system including a blood pressure sensor and a heart rate sensor, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including an electrode, providing a control system coupled to the baroreflex therapy system and the implantable measurement device, the control system programmed to automatically determine an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, determine arterial stiffness of the blood vessel based on the impedance, determine blood pressure and heart rate, and activate, deactivate or otherwise modulate the baroreflex therapy system to deliver a baroreflex therapy based on the blood pressure, heart rate and arterial stiffness.

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Номер записи: 47
21-02-2013 дата публикации

Systems and Methods for Identifying Vascular Borders

Номер: US20130046167A1
Автор: Jignesh Shah
Принадлежит: Volcano Corp

A method comprises gathering intravascular photoacoustic (IVPA) data using a transducer inserted into a vessel of a patient. The method further includes modulating the IVPA data to determine a first tissue border and displaying a border map representing the first tissue border.

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Номер записи: 48
14-03-2013 дата публикации

Method and system for patient-specific modeling of blood flow

Номер: US20130064438A1
Автор: Charles A. Taylor, Christopher K. Zarins, Gilwoo Choi, Timothy A. Fonte, Ying Bai
Принадлежит: HeartFlow Inc

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

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Номер записи: 49
14-03-2013 дата публикации

Method and system for patient-specific modeling of blood flow

Номер: US20130066618A1
Автор: Charles A. Taylor, Christopher K. Zarins, Gilwoo Choi, Timothy A. Fonte, Ying Bai
Принадлежит: HeartFlow Inc

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

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Номер записи: 50
21-03-2013 дата публикации

Systems and Methods for Determining a Sleep Disorder Based on Positioning of the Tongue

Номер: US20130072999A1
Автор: Adi Mashiach
Принадлежит: Nyxoah SA

Devices and methods are disclosed that include an external unit comprising at least one processor. The processor may be configured to receive a signal indicative of tongue movement in a subject from an implant unit implanted in the subject, determine whether the tongue movement is representative of sleep disordered breathing, generate a modulation control signal to correct the sleep disordered breathing when the at least one processor determines an occurrence of sleep disordered breathing.

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Номер записи: 51
28-03-2013 дата публикации

Imaging Method using Magnetic Small Particles and Corresponding Device

Номер: US20130079623A1
Автор: Behr Volker C., Rueckert Martin
Принадлежит:

The invention relates to a method for imaging from a distribution of small magnetic particles. According to said method, the magnetisation of the small particles is rotated asynchronously to the magnetic field by means of an outer magnetic field of suitable field intensity and rotational frequency, which rotates about a longitudinal axis (z), whereby an asynchronous average rotational frequency is generated for a set of particles according to the field intensity; a spatial dependence is impressed on each set of particles by means of a magnetic gradient field of the asynchronous average rotational frequency; the frequency parts of the superpositioned transverse magnetisation (MQ) of the set of particles are detected; and a spatially resolved distribution of the transverse magnetisation (MQ) determines the small particles and emits same by means of the frequency parts. The invention also relates to a suitable device (). An improved spatial resolution can be obtained, compared to the previous magnetic particle imaging methods, with essentially lower field intensities. 1. A method for imaging from a distribution of magnetic small particles , whereinby means of an external magnetic field of suitable field strength and rotation frequency rotating about a longitudinal axis (z), the magnetizations of the small particles are set in a rotation which is asynchronous with respect to the magnetic field, by means of which an asynchronous average rotation frequency dependent on the field strength results for a particle ensemble,a position dependency is imposed by means of a magnetic gradient field with the asynchronous average rotation frequency of the respective particle ensemble,{'sub': 'Q', 'the frequency components of the superimposed transverse magnetization (M) of the particle ensemble are recorded and'}{'sub': 'Q', 'spatially resolved distribution of the transverse magnetization (M) is determined by means of the frequency components and is output.'}2. The method as claimed ...

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Номер записи: 52
28-03-2013 дата публикации

Ct - mri hyrbrid apparatus and method of implementing the same

Номер: US20130079625A1
Автор: Georges HOBEIKA
Принадлежит: Individual

An apparatus and method for non-invasively obtaining an image featuring information on internal human tissues, and more particularly to an apparatus and method for integrating computed tomography (CT) or computerized axial tomography (CAT) and magnetic resonance imaging (MRI) to provide high spatial-accurate resolution images which feature tumor information on human internal tissues especially as a part of a radiotherapy treatment. The apparatus includes a first section for obtaining a first set of images of a subject using a first method, a second section for obtaining a second set of images of the subject using the second method, the second method being different from the first method, and a board for carrying the subject through the first and second sections, the board being movable between the first and second sections.

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Номер записи: 53
28-03-2013 дата публикации

Insert measuring system having a polymer articular surface

Номер: US20130079884A1
Автор: Andrew P. Miller, Andrew U. Chase, Jason Addink, Marc Stein
Принадлежит: ORTHOSENSOR INC

At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load-bearing surface. At least one of the support structures comprises polycarbonate. The polycarbonate allows short-range transmission of measurement data. The height of the insert is less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The internal cavity is isolated from the external environment and can be hermetically sealed.

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Номер записи: 54
04-04-2013 дата публикации

Antenna structures for implantable medical devices

Номер: US20130085350A1
Автор: Michael A. Schugt, Yanzhu Zhao
Принадлежит: MEDTRONIC INC

This disclosure describes antenna structures for use with implantable medical devices (IMDs). The IMD may include a housing that hermetically encloses electronic components of the IMD and a fixation mechanism that attaches the IMD to a target location within a patient, such as a wall of a vessel. The fixation mechanism may function as a radiating element of an antenna of the IMD. The fixation mechanism may be attached to a housing of the IMD with two different members. One member may be an anchoring structure that mechanically anchors the fixation mechanism to the housing. The second member may be a connector that electrically connects the fixation mechanism to the housing such that the fixation mechanism is configured to transmit and/or receive communication signals with other implantable or external devices.

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Номер записи: 55
04-04-2013 дата публикации

Devices and Methods for Delivering Energy as a Function of Condition Severity

Номер: US20130085541A1
Автор: Adi Mashiach
Принадлежит: Nyxoah SA

A device for regulating energy delivery to an implanted circuit is disclosed. The device may include at least one implantable circuit and at least one pair of implantable electrodes in electrical communication with the circuit. The at least one pair of implantable electrodes may be configured to modulate at least one nerve. The at least one implantable circuit may be configured deliver a signal to the at least one pair of implantable electrodes. The signal may have at least one of a power level or a duration determined based on a severity of a detected physiologic condition.

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Номер записи: 56
04-04-2013 дата публикации

Apparatus and Method to Control an Implant

Номер: US20130085544A1
Автор: Adi Mashiach
Принадлежит: Nyxoah SA

A device according to some embodiments of the present disclosure includes a housing configured to retain a battery, a primary antenna associated with the housing, and at least one processor in electrical communication with the battery and the primary antenna. In some embodiments, the at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device during a treatment session of at least three hours in duration, wherein the primary signal is generated using power supplied by the battery and includes a pulse train, the pulse train including a plurality of modulation pulses.

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Номер записи: 57
04-04-2013 дата публикации

Device and Method for Modulating Nerves Using Parallel Electric Fields

Номер: US20130085558A1
Автор: Adi Mashiach
Принадлежит: Nyxoah SA

A device may include at least one pair of modulation electrodes configured for implantation in the vicinity of a nerve to be modulated such that the electrodes are spaced apart from one another along a longitudinal direction of the nerve to be modulated. The electrodes may be further configured to facilitate an electric field in response to an applied electric signal, the electric field including field lines extending in the longitudinal direction of the nerve to be modulated. The device may further include at least one circuit in electrical communication with the at least one pair of modulation electrodes and being configured to cause application of the electric signal applied at the at least one pair of modulation electrodes.

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Номер записи: 58
04-04-2013 дата публикации

System and Method for Nerve Modulation Using Noncontacting Electrodes

Номер: US20130085560A1
Автор: Adi Mashiach
Принадлежит: Nyxoah SA

An implant unit configured for implantation into a body of a subject may include an antenna configured to receive a signal. The implant unit may also include at least one pair of modulation electrodes configured to be implanted into the body of the subject in the vicinity of at least one nerve to be modulated, the at least one pair of modulation electrodes being configured to receive an applied electric signal in response to the signal received by the antenna and generate an electrical field to modulate the at least one nerve from a position where the at least one pair of modulation electrodes does not contact the at least one nerve.

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Номер записи: 59
11-04-2013 дата публикации

INTRAOCULAR PHYSIOLOGICAL SENSOR

Номер: US20130090534A1
Автор: Applegate David, Burns Thomas W., Curry Kenneth Martin, Haffner David S., Heitzmann Harold A., NOGALES Bruce
Принадлежит:

An implantable intraocular physiological sensor for measuring intraocular pressure, glucose concentration in the aqueous humor, and other physiological characteristics. The implantable intraocular physiological sensor may be at least partially powered by a fuel cell, such as an electrochemical glucose fuel cell. The implantable intraocular physiological sensor may wirelessly transmit measurements to an external device. In addition, the implantable intraocular physiological sensor may incorporate aqueous drainage and/or drug delivery features. 1. An implantable physiological measurement device comprising:a sensing module configured to measure a physiological characteristic of an organism; anda fuel cell configured to produce power using a substance found in the organism, wherein the fuel cell is configured to supply operating power to one or more components provided in the device.2. The device of claim 1 , wherein the fuel cell is an electrochemical fuel cell that provides electrical power to the one or more components provided in the device.3. The device of claim 2 , wherein the device is configured to be implanted in an eye.4. The device of claim 3 , wherein the electrochemical fuel cell comprises a glucose fuel cell.5. The device of claim 4 , wherein the sensing module is configured to measure intraocular pressure or glucose concentration in the aqueous humor of the eye.6. The device of claim 5 , wherein the sensing module is configured to measure glucose concentration based on the amount of electrical power produced by the fuel cell.7. The device of claim 1 , wherein the physiological characteristic corresponds to the amount of the substance used by the electrochemical fuel cell to produce electrical power.8. The device of claim 1 , wherein the one or more components comprise a transmitter and antenna configured to wirelessly transmit measurements from the sensing module to an external device claim 1 , and wherein the transmitter is configured to be at least ...

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Номер записи: 60
18-04-2013 дата публикации

Electrogram classification algorithm

Номер: US20130096449A1
Автор: Amisha S. Patel, Jian Cao, Karen J. Kleckner
Принадлежит: MEDTRONIC INC

The present disclosure is directed to the classification of cardiac episodes using an algorithm. In various examples, an episode classification algorithm evaluates electrogram signal data using a probabilistic ventricular oversensing algorithm. The algorithm may look at a plurality of factors weighing for and against a determination of ventricular oversensing. In some examples, the algorithm may also determine whether the cardiac episode includes atrial sensing issues.

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Номер записи: 61
25-04-2013 дата публикации

Method For Correcting Susceptibility-Induced Image Artifacts In MRI After Prospective Motion Correction

Номер: US20130102879A1
Автор: Boegle Rainer, Maclaren Julian, Zaitsev Maxim
Принадлежит: Universitaetsklinikum Freiburg

A method of magnetic resonance imaging (MRI) is characterized by the following steps: a) forming a susceptibility model () of at least a part of a subject (S), including an imaged body part (), by using a structural magnetic resonance image () of the part of the subject (S) and/or prior knowledge of the anatomy of the subject (S); b) computing susceptibility-induced field deviations () present in the imaging volume at each time MR signals are acquired using the susceptibility model () and the knowledge of a monitored position and monitored orientation () of the part of the subject (S) at that time; c) using the information about the susceptibility-induced field deviations () derived in b) for image correction (), in particular correction of image distortions and/or intensity modulations. The quality of magnetic resonance imaging of moving subjects is thereby improved. 116-. (canceled)17. A method of magnetic resonance imaging (MRI) , wherein a body part of an animal or human subject in an imaging volume is imaged by acquiring a plurality of spatially-encoded MR signals from the imaging volume where susceptibility-induced field deviations reduce a homogeneity of a main magnetic field B , and wherein a prospective motion correction is applied , updating the imaging volume between the acquisition of the spatially-encoded MR signals based on a monitored position of the body part , the method comprising the steps of:a) forming a susceptibility model of at least part of the subject, including an imaged body part, using a structural magnetic resonance image of that part of the subject and/or prior knowledge of an anatomy of the subject;b) computing susceptibility-induced field deviations present in the imaging volume at each time MR signals are acquired using the susceptibility model and the knowledge of a monitored position and monitored orientation of the part of the subject at those times at which MR signals are acquired; andc) using information about the susceptibility ...

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Номер записи: 62
25-04-2013 дата публикации

Micro Vein Enhancer

Номер: US20130102905A1
Автор: David Hunt, Graham Marshal, Mark Mock, Robert Roth, Ron Goldman, Stephen P. Conlon
Принадлежит: David Hunt, Graham Marshal, Mark Mock, Robert Roth, Ron Goldman, Stephen P. Conlon

The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.

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Номер записи: 63
02-05-2013 дата публикации

System, method and computer-accessible medium for performing attenuation-corrected multispectral luminescenece tomography of cerenkov and bioluminescent light sources

Номер: US20130108132A1
Автор: Alexander Klose
Принадлежит: Columbia University of New York

The present disclosure can provide apparatus, system, methods, and computer-accessible medium for generating particular information which is at least one of three-dimensional information or intensity information of a tissue portion which can include at least one of a tissue surface or a tissue volume. For example, the exemplary method can include determining a light intensity distribution of light provided on the tissue portion, using the light intensity distribution, determining one or more attenuation maps of the tissue portion, obtaining one or more multispectral measurements of the light intensity distribution on the tissue portion taken from one or more views, and generating the particular information using an image reconstruction procedure in conjunction with data from the one or more tissue attenuation maps and the multispectral measurements.

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Номер записи: 64
09-05-2013 дата публикации

MEDICAL IMAGING METHOD AND SYSTEM

Номер: US20130116542A1
Автор: Gross Patrick
Принадлежит:

In an imaging procedure, sound pressure is generated by applying ultrasound to the region to be imaged in order to cause a deformation of tissue therein from at least one acquired ultrasound image data set, first data are determined that represent, with spatial resolution, the deformation of the tissue as a reaction to the sound pressure. At least one magnetic resonance image data set is acquired, from which second data are determined that represent, with spatial resolution, the deformation of the tissue as a reaction to the sound pressure. The at least one ultrasound image data set and the at least one magnetic resonance image data set are brought into registration with each other by a comparison of the first data and the second data. 1. A method for medical imaging , comprising:subjecting tissue in a region of an examination subject to sound pressure by applying ultrasound to said region, in order to cause a deformation of said tissue in said region as a reaction to said sound pressure;operating an ultrasound imaging device to acquire at least one ultrasound image data set of said region during or after subjecting said tissue to said sound pressure;in a processor, determining first data from said at least one ultrasound image data set that represent, with spatial resolution, said deformation of said tissue as a reaction to said sound pressure;operating a magnetic resonance imaging device to acquire at least one magnetic resonance image data set of said region during or after said application of said sound pressure to said tissue;in said processor, determining second data from said at least one magnetic resonance image data set that represent, with spatial resolution, said deformation of said tissue as a reaction to said sound pressure; andin said processor, bringing said at least one ultrasound image data set and said at least one magnetic resonance image data set into registration with each other based on a comparison of said first data and said second data with ...

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Номер записи: 65
16-05-2013 дата публикации

METHOD AND MAGNETIC RESONANCE APPARATUS TO MEASURE STRUCTURES OF THE HUMAN BRAIN

Номер: US20130123606A1
Автор: Heismann Bjoern, Schmidt Sebastian
Принадлежит:

In a method to measure characteristic structure sizes of the human brain, which structure sizes can be used as biomarkers for a diagnosis of Alzheimer's, using a magnetic resonance device, manual and/or automatic localization of the hippocampus takes place in a preliminary magnetic resonance acquisition, followed by selection of at least one measurement axis that proceeds through the hippocampus. For each selected measurement axis, magnetic resonance data are acquired for a longitudinal, in particular rod-shaped, acquisition region proceeding along the measurement axis. Determination of the spatially resolved structure sizes is implemented from the magnetic resonance data. 1. A method to measure a characteristic size of an anatomical structure of a human brain , comprising:operating a magnetic resonance (MR) data acquisition unit to obtain a preliminary magnetic resonance data set of a human brain in which the hippocampus is represented;using a processor, localizing the hippocampus in said preliminary magnetic resonance data set;using said processor, selecting at least one measurement axis that proceeds through the hippocampus;for each selected measurement axis, operating said MR data acquisition unit to acquire diagnostic magnetic resonance data from a longitudinal acquisition region of the brain, said longitudinal acquisition region comprising a longitudinal extent along said measurement axis and having an extent perpendicular to said longitudinal extent that is substantially shorter than said longitudinal extent; andusing said processor, determining a spatially-resolved structural size of a structure represented in said MR data acquired from said acquisition region that is a biomarker for diagnosis of a presence of Alzheimer's disease.2. A method as claimed in comprising automatically claim 1 , in said processor claim 1 , localizing the hippocampus in said preliminary magnetic resonance data set.3. A method as claimed in comprising automatically claim 1 , in said ...

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Номер записи: 66
16-05-2013 дата публикации

Flexible Coil for MR Experiments on Small Animals

Номер: US20130123609A1
Автор: Lanz Titus, Odoj Florian
Принадлежит: RAPID Biomedical GmbH

A flexible coil device for supporting imaging experiments on subjects, such as small animals. The device has a rigid part where electronics are accommodated and a flexible loop acting as a receiving coil that picks up the imaging signal. The flexible loop allows its shape to be adapted to the particular shape of the imaged subject at the point of placement. This provides a better filling factor and hence better SNR of the region of interest (ROI). This has the advantage that various imaging applications pose less of a compromise than with rigid coils. The flexible loop can be positioned right against the region of interest (ROI) and so maximises the filling factor and the image SNR. 1. A device for receiving an imaging signal , comprising;a coil loop for receiving the imaging signal;processing electronics for processing a signal received by the coil loop;a base portion for enclosing the processing electronics;a flexible portion for enclosing the receiving coil, wherein said flexible portion is adapted for conforming to any one of a number of different locations on the body of a subject for receiving the imaging signal from a desired region of interest of a subject being imaged.2. The device of claim 1 , wherein said flexible portion is formed into a loop.3. The device of claim 1 , wherein said processing electronics includes at least one of a tune capacitor claim 1 , a match capacitor claim 1 , a circuit to actively decouple the coil claim 1 , an in-line preamplifier claim 1 , or a cable wave trap claim 1 ,4. The device of claim 1 , wherein said processing electronics are provided on a rigid part to prevent said processing electronics from being damaged as said flexible portion is being conformed.5. The device of claim 1 , wherein said flexible portion and said base portion are formed from a common top portion and a common bottom portion connected together for holding said processing electronics and said receiving coil.6. The device of claim 5 , wherein said ...

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Номер записи: 67
16-05-2013 дата публикации

Method and Apparatus for the Non-Invasive Measurement of Pulse Transit Times (PTT)

Номер: US20130123617A1
Автор: Adler Andrew, Brunner Josef X., Farrario Damien, Sola i Caros Josep
Принадлежит: CSEM SA

Method and apparatus for measuring a pulse transit time (PTT) value of a subject, comprising: measuring a first arterial pressure pulse arrival time (PAT) and measuring a second PAT value; calculating a PTT value from the difference between the first PAT value and the second PAT value; processing a sequence of electrical impedance tomography (EIT) images to identify at least one region of interest (ROI); and estimating at least one of the first and second PAT value from the variation of impedance value determined from said at least one ROI. The method allows for the non-invasive and continuous measurement of the PTT value and arterial blood pressures. 1. Method for measuring a pulse transit time (PTT) value of a subject , comprising:measuring a first arterial pressure pulse arrival time (PAT) and measuring a second PAT value;calculating a PTT value from the difference between the first PAT value and the second PAT value;{'b': '10', 'processing a sequence of electrical impedance tomography (EIT) images () to identify at least one region of interest (ROI); and'}estimating at least one of the first and second PAT value from the variation of impedance value determined from said at least one ROI.2. Method according to claim 1 , wherein said processing a sequence of EIT images comprises providing an imaging device adapted to record impedance signal distribution (EIT image) of the subject; and during a predetermined measuring time period claim 1 , measuring a sequence of temporally discrete EIT images of the subject using the EIT imaging device claim 1 , each EIT image comprising a plurality of pixels claim 1 , each pixel representing an impedance value.3. Method according to claim 2 , wherein said at least one ROI comprises a subset of said plurality of EIT pixels.4. Method according to claim 2 , wherein said determining at least one ROI comprises using one or a combination of the methods comprising: analyzing the sequence of EIT images claim 2 , and analyzing images ...

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Номер записи: 68
23-05-2013 дата публикации

Multimodal detection of tissue abnormalities based on raman and background fluorescence spectroscopy

Номер: US20130131488A1
Автор: David I. McLean, Haishan Zeng, Harvey Lui, Zhiwei Huang
Принадлежит: British Columbia Cancer Agency BCCA

Methods and apparatus for classifying tissue use features of Raman spectra and background fluorescent spectra. The spectra may be acquired in the near-infrared wavelengths. Principal component analysis and linear discriminant analysis of reference spectra may be used to obtain a classification function that accepts features of the Raman and background fluorescence spectra for test tissue and yields an indication as to the likelihood that the test tissue is abnormal. The methods and apparatus may be applied to screening for skin cancers or other diseases.

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Номер записи: 69
23-05-2013 дата публикации

Method and apparatus for performing dual-modality imaging

Номер: US20130131493A1
Автор: Alexander Ganin, Joan M. Hanson, Kathryn M. Littlejohn, Ling Sun, Scott David Wollenweber, William J. Bridge
Принадлежит: General Electric Co

A method for performing an examination of a patient using a dual-modality imaging system includes accessing a list that includes a magnetic resonance imaging (MRI) examination protocol to be used to perform a predetermined MRI examination, the examination protocol including a plurality of MRI protocol actions, receiving an input selecting at least one of the MRI protocol actions, scanning the patient using the MRI examination protocol, scanning the patient using a positron emission tomography (PET) imaging system to acquire PET data, and marking the PET data, using a first visual indication, to indicate the selected MRI protocol action. An imaging system and a non-transitory computer readable medium are also described herein.

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Номер записи: 70
23-05-2013 дата публикации

Sensing zone for spatially relevant electrical information

Номер: US20130131529A1
Автор: Brian P. GEORGE, Charulatha Ramanathan, Harold Wodlinger, Jonathan D. SMALL, Lalita BHETWAL, Maria Strom, Ping Jia
Принадлежит: Cardioinsight Technologies Inc

Systems and methods are disclosed to determine one or more sensing zones on a body surface for electrocardiographic mapping of a region of interest associated with the heart. The sensing zone can be utilized to facilitate acquisition, processing and mapping of electrical activity for the corresponding region of interest. In other examples, an application-specific arrangement of electrodes can also be provided based on the sensing zone that is determined for the region of interest.

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Номер записи: 71
30-05-2013 дата публикации

Method and system for automatically setting a landmark for brain scans

Номер: US20130136329A1
Автор: Robert David Darrow, Thomas Kwok-Fah Foo, Vivek Prabhakar Vaidya, Xiaodong Tao
Принадлежит: General Electric Co

A method, system and apparatus for automatically setting a landmark for brain scans are described. In one embodiment, a method for medical image processing is described. The method comprises obtaining, by an imaging device, at least one image of a head of a subject. In addition, the method also comprises identifying, by a computer-based system, a reference feature in the at least one image associated with the head. The method also comprises automatically setting, by the computer-based system, a landmark based, at least in part, upon the reference feature.

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Номер записи: 72
30-05-2013 дата публикации

MR GAMMA HYBRID IMAGING SYSTEM

Номер: US20130137964A1
Автор: Schellenberg James
Принадлежит:

A pendant breast imaging system that operates with a MRI system and which allows a planar gamma camera breast imaging system to be positioned away from the breast area while MRI imaging is occurring, and which then moves into breast imaging position after MRI imaging is complete, and which can again be removed from the breast area to allow intervention to occur is described. It may use various collimator or scintillator materials and designs. 1. A method of imaging a breast comprising:providing a patient lying on a table, said table having a raised platform with openings for the face and breasts of the patient;providing a bore based or slab based magnetic resonance imaging (MRI) system having a radiofrequency (RF) coil, said RF coil having an opening therein;generating an MRI image of the breast of interest by placing the RF coil proximal to the breast of interest; an MRI-compatible gamma camera head arranged to be inserted through the opening in said RF coil;', 'a gamma shield; and', 'a non-MRI compatible processing system connected to the gamma camera head by cabling;, 'providing a magnetic resonance imaging (MRI) compatible gamma camera comprisinginserting the gamma camera head through the opening in the RF coil such that the gamma camera head is closer to the breast of interest than the inner diameter of the RF coil; andgenerating a gamma image of the breast of interest, characterized in that the magnetic resonance imaging and the gamma imaging are carried out sequentially and the patient is not moved or repositioned during the imaging process.2. The method according to wherein the gamma camera head comprises a collimator claim 1 , a scintillator claim 1 , a detector and an electronics assembly.3. The method according to wherein the gamma camera head is substantially planar.4. The method according to wherein the gamma camera head is connected to an articulated arm for positioning the gamma camera head.5. The method according to further comprising a breast paddle ...

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Номер записи: 73
30-05-2013 дата публикации

Implantable marker for a surgical navigation system, the marker having a spike for removably securing the marker to the tissue to be tracked

Номер: US20130137972A1
Автор: Chunwu Wu, Donald J. Malackowski, Paul M. Hoekstra, Robert Brindley
Принадлежит: Individual

A marker for use with a surgical navigation system for tracking the tissue with which the marker is associated. The overall dimensions of the mark is such that it is shaped to be disposed below the skin of the patient in which the marker is implanted. The marker has a stem or a spike that allows the marker to be implanted in hard tissue such as bone. A head, containing navigation system components is located above the stem or spike. Once the procedure is completed the marker is removed from the patient by breaking the head free from the stem Alternatively the head may be rotated to cause the whole of the marker to break free from the bone in which the marker is implanted.

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Номер записи: 74
06-06-2013 дата публикации

MULTI-MODAL IMAGING OF BLOOD FLOW

Номер: US20130144140A1
Автор: Frederick Blaise, Tong Yunjie
Принадлежит:

The application features methods, devices, and systems for measuring blood flow in a subject. The computer-implemented methods include receiving functional magnetic resonance imaging (fMRI) data that provides information on at least one of volume or oxygenation of blood at one or more locations in a body over a first predetermined length of time. The methods also include receiving near-infrared spectroscopic (NIRS) imaging or measurement data representing at least one of blood concentration or oxygenation at a first portion of the body over a second predetermined length of time. The methods further include deriving, from the fMRI data corresponding to a second portion of the body, a time varying data set representing changes in blood oxygenation or volume or both blood oxygenation and volume at the second portion over the first predetermined length of time and determining, by a computing device, a time delay and a value of a similarity metric corresponding to a part of the spectroscopic imaging data that most closely matches the time varying data set. The time delay represents a difference between a first time in which blood flows from a third portion in the body to the first portion and a second time in which blood flows to the second portion from the third portion. The value of the similarity metric represents an amount of blood at the second portion. An estimate of a characteristic of at least one of blood flow or blood volume in the second portion at a given time is determined based on the time delay and the value of the similarity metric. 136-. (canceled)37. A computer-implemented method for measuring at least one of blood flow or volume in a subject , the method comprising:receiving functional magnetic resonance imaging (fMRI) data that provides information on at least one of volume or oxygenation of blood at one or more locations in a body over a first predetermined length of time;receiving spectroscopic measurement data representing at least one of blood ...

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Номер записи: 75
06-06-2013 дата публикации

Chronically implanted abdominal pressure sensor for continuous ambulatory assessment of renal functions

Номер: US20130144174A1
Автор: Bin Mi, Binh C Tran, John D. Hatlestad, Ronald W. Heil, Jr.
Принадлежит: Individual

An implantable system for ambulatory monitoring of a high-risk heart failure patient includes a first pressure sensor implantable within an abdomen of the patient for sensing and generating an output representative of a baseline intra-abdominal pressure value of the patient and for chronically sensing and generating an output representative of an intra-abdominal pressure value of the patient at periodic intervals. At least one second implantable sensor is provided for sensing and generating an output representative of a second physiological parameter of the patient. Additionally, the system includes a processor for correlating the output of the first pressure sensor and the second physiologic sensor, and for comparing differences between the baseline intra-abdominal pressure value and subsequent intra-abdominal pressure values. The processor can reside in another implantable device or in an external device/system.

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Номер записи: 76
13-06-2013 дата публикации

Magnetic resonance imaging methods for rib identification

Номер: US20130150704A1
Автор: Shuki Vitek, Yoav Lévy, Yoav Medan
Принадлежит: Individual

A method for spatially localizing a rib cage prior to transcostal ultrasound treatment of visceral tissue includes computationally refining a three-dimensional model of the rib cage based on image slices taken at multiple locations along the ribs with orientations dependent on local rib orientations.

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Номер записи: 77
13-06-2013 дата публикации

MAPPING SYSTEM AND METHOD FOR MEDICAL PROCEDURES

Номер: US20130150732A1
Автор: "T Hooft Gert Wim", Chan Raymond Emmanuel, Deladi Szabolcs, Desjardins Adrien, Manzke Robert
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS N.V.

A system and method for mapping interluminal structures includes an elongated flexible instrument (). An optical shape sensing device () is disposed within the flexible instrument and is configured to determine a shape of the flexible instrument relative to a reference. The shape sensing device is configured to collect information based on its configuration to map an interluminal structure during a procedure. An imaging enabled ablation device () is mounted at or near a distal end portion of the flexible instrument. 1. A system for mapping interluminal structures , comprising:{'b': '102', 'an elongated flexible instrument ();'}{'b': 152', '154, 'an optical shape sensing device (, ) disposed within the flexible instrument and configured to determine a shape of the flexible instrument relative to a reference, the shape sensing device configured to collect information based on its configuration to map an interluminal structure during a procedure; and'}{'b': '117', 'an imaging enabled ablation device () mounted at or near a distal end portion of the flexible instrument.'}2152154154. The system as recited in claim 1 , wherein the optical shape sensing device includes an optical fiber () having at least one of Fiber Bragg Gratings (FBGs) () and a Rayleigh scatter interrogation setup () for sensing strain in the fiber.3152154. The system as recited in claim 1 , wherein the optical shape sensing device includes an area of higher sensitivity by including an area with a higher number of optical fibers () having optical strain sensors ().4. The system as recited in claim 1 , wherein the optical shape sensing device includes one of a spiral shape claim 1 , a ring shape and a loop shape.5. The system as recited in claim 1 , wherein the reference includes one of a position on the flexible instrument and an anatomical reference.6102. The system as recited in claim 1 , wherein the flexible instrument () includes one of a catheter and an endoscope.7. A system for mapping ...

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Номер записи: 78
20-06-2013 дата публикации

OBSERVATION DEVICE, OBSERVATION PROGRAM, AND OBSERVATION SYSTEM

Номер: US20130156287A1
Автор: Houjou Mikio, ODA Atsushi
Принадлежит: SANYO ELECTRIC CO., LTD

An observation device () is provided with: a general observation unit () for observing sample cells by observing an entire container (C) containing the cells and a culture solution; and a magnification observation unit () for magnifying a region within the container (C) and observing the cells, the general observation unit () and the magnification observation unit () each individually having lighting for illuminating the cells with light, and an optical system for observing the cells. The general observation unit () and the magnification observation unit () are thereby each provided with an individual optical system and lighting, making it possible to configure an appropriate observation unit for use both when the cells are observed by observing the entire container (C) and when a part within the container (C) is magnified and the cells are observed. 122.-. (canceled)23. An observation program for making a computer execute processing , the processing comprising:overall image sensing processing for taking an image of a sample through taking an image of an entire container containing the sample and a solution;sample mass discrimination processing for discriminating from the image taken in the overall image sensing processing a sample mass, which is a mass of a plurality of pieces of the sample;coordinate detection processing for detecting coordinates of a center of the sample mass discriminated in the sample mass discrimination processing;magnified image sensing processing for taking an image of the sample mass on a magnified scale about, as a center, the coordinates detected in the coordinate detection processing; andtime keeping processing for counting days and hours from a start of observation of the sample, whereinin the sample mass discrimination processing, discrimination of the magnified observation target sample mass is repeated every predetermined period counted in the time keeping processing with respect to sample mass discrimination until, from the image ...

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Номер записи: 79
20-06-2013 дата публикации

System For Diagnosing and Identifying Genetic Features, Genetic and Congenital Syndromes And Developmental Abnormalities

Номер: US20130158437A1
Автор: Moalem Sharon
Принадлежит:

The invention is a system for diagnosing and identifying of genetic characteristics, genetic syndromes, congenital syndromes, developmental and exposure related syndromes, and veterinary breed characteristics in fetuses, children and adults, in humans and animals. The system takes a set of facial anatomical measurements of an individual target and biological relatives of the individual target, normalizes the facial anatomical measurements, and compares the normalized measurements with a database of set of anatomical features associated with a desired diagnostic data set. 1. A system for the identification and diagnosis of genetic features , genetic syndromes , congenital and developmental abnormalities of a human or animal target , the system comprising:a first data collection module, capable of obtaining facial anatomical measurements of the target;a database of data correlating facial anatomical measurements with a diagnostic data set;a second data collection module, capable of obtaining facial anatomical measurements of biological relatives of the target;a data filter module, capable of comparing the target's facial anatomical measurements with the facial anatomical measurements of the biological relatives to produce a filtered set of target facial measurements;a data processing module, capable of comparing the filtered set of target facial anatomical measurements with the database; anda reporting module, capable of providing a report of the comparison.2. The system of claim 1 , where the diagnostic data set comprises genetic characteristics.3. The system of claim 1 , where the diagnostic data set comprises genetic syndromes.4. The system of claim 1 , where the diagnostic data set comprises congenital syndromes.5. The system of claim 1 , where the diagnostic data set comprises developmental and exposure related syndromes.6. The system of claim 1 , where the diagnostic data set comprises veterinary breed characteristics.7. The system of claim 1 , further ...

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Номер записи: 80
27-06-2013 дата публикации

METHODS AND APPARATUS FOR IMAGING, DETECTING, AND MONITORING SURFICIAL AND SUBDERMAL INFLAMMATION

Номер: US20130162796A1
Автор: Bharara Manish, Farrow Daniel
Принадлежит: The Arizona Board of Regents on Behalf of the University of Arizona

Described are imaging apparatus and methods for imaging an area of interest, such as selected regions on a surface of a human or other living subject, by thermal and non-thermal means. Methods of using the apparatus to detect and monitor wounds in an area of interest on a subject are also described. The apparatus and methods have particular utility for detection and monitoring of ulcerations and general wound degradations, as well as of conditions that could result in formation of such lesions. 1. An imaging apparatus , comprising:a first image sensor that produces, when directed toward an area of interest on a surface of a living subject, a thermal image of the area of interest;a second image sensor that produces, when directed toward the area of interest on the surface of the living subject, a non-thermal image of the area of interest;a display; anda controller operably connected to the first image sensor, the second image sensor, and the display,wherein the controller is programmed toalign respective images of the area of interest obtained by the first image sensor and by the second image sensor to produce an aligned image,output the aligned image to the display, andprocess the aligned image,wherein processing the aligned image comprises at least one of(a) determining and analyzing one or more thermal and spatial parameters of the area of interest in the aligned image;(b) determining and integrating one or more thermal and spatial parameters of the area of interest into a model; and(c) animating the aligned image in a time sequence with at least one previously-obtained aligned image of the area of interest.2. The imaging apparatus of claim 1 , further comprising a data-storage device coupled to the controller and configured to store the aligned image.3. The imaging apparatus of claim 1 , wherein the first image sensor comprises an infrared camera.4. The imaging apparatus of claim 1 , wherein the second image sensor comprises a visible-light camera.5. The imaging ...

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Номер записи: 81
27-06-2013 дата публикации

Systems and methods for making and using medical ablation systems having mapping catheters with improved anchoring ability

Номер: US20130165759A1
Автор: David McGee, Isaac Kim, Josef V. Koblish
Принадлежит: Boston Scientific Scimed Inc

A mapping catheter includes an elongated body for inserting into patient vasculature. A distal end of the elongated body includes a distal portion that includes a plurality of electrodes, a proximal portion disposed proximal to the distal portion, and a reduced-dimension portion disposed between the proximal and distal portions. The distal end is formed, at least in part, from a memory shape material that bends into a preformed shape upon release from a confined space. The preformed shape includes a first loop formed, at least in part, by the distal portion. The first loop is transverse to a longitudinal axis of the proximal portion. The reduced-dimension portion is configured and arranged to bend such that the reduced-dimension section advances distally through the first loop when the first loop is held in a fixed position and a force is applied distally along the longitudinal axis of the proximal portion.

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Номер записи: 82
27-06-2013 дата публикации

PROPERTY INFORMATION ACQUIRING APPARATUS

Номер: US20130165765A1
Автор: Nishihara Hiroshi
Принадлежит: CANON KABUSHIKI KAISHA

The present invention employs a property information acquiring apparatus comprising: a supporting unit configured to support a test subject and include an aperture into which a tested part of the test subject is inserted; a holding unit configured to hold the tested part inserted into the aperture; and a pressing unit that includes a receiving unit for receiving information relating to a property of the tested part and is pushed against a surface of the holding unit different from a surface for holding a test object, wherein the supporting unit includes a restricting part that restricts deformation caused in the holding unit by the pressing of the pressing unit. 1. A property information acquiring apparatus comprising:a supporting unit configured to support a test subject and include an aperture into which a tested part of the test subject is inserted;a holding unit configured to hold the tested part inserted into the aperture; anda pressing unit that includes a receiving unit for receiving information relating to a property of the tested part and is pushed against a surface of the holding unit different from a surface for holding a test object, whereinthe supporting unit includes a restricting part that restricts deformation caused in the holding unit by the pressing of the pressing unit.2. The property information acquiring apparatus according to claim 1 , wherein the restricting part is a portion claim 1 , of the supporting unit claim 1 , that holds the holding unit.3. The property information acquiring apparatus according to claim 1 , wherein the supporting unit includes a bed.4. The property information acquiring apparatus according to claim 1 , further comprising a light irradiating unit configured to irradiate the tested part with light claim 1 , wherein the receiving unit receives an acoustic wave generated at the tested part by the light irradiating unit irradiating the tested part with light.5. The property information acquiring apparatus according to ...

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Номер записи: 83
04-07-2013 дата публикации

IMAGE-OVERLAY MEDICAL EVALUATION DEVICES AND TECHNIQUES

Номер: US20130172731A1
Автор: Gole Philip D.
Принадлежит:

A system and methods are provided for evaluating the position of surgical implants or openings formed in anatomical tissue during medical procedures, in which an initial 3-dimensional image of the anatomical tissue is combinable with one or more subsequent 3-dimensional images of the same or correlating tissue, and without the use of ionizing radiation on a patient for at least the subsequent images. The system includes a software program, a computer with display, a radiographic image scanning device, and a non-radiographic image scanning device. The computer accesses a medical patient information database and a medical implant database for images used by the software program. A pre-operative image is combined with subsequent images to facilitate evaluation of the proposed placement of a surgical implant or opening relative to tissues of the patient anatomy. Methods of evaluating the accuracy of surgical guides and of fabricating surgical guides are also disclosed. 1. A medical imaging display system for collecting and displaying medical images , said system comprising:a software program configured to enable the manipulation and overlaying a plurality of digital images;a computer configured to execute said software program;a display in communication with said computer;a radiographic image scanning device in communication with said computer;a non-radiographic image scanning device in communication with said computer;a medical patient information database for storing patient medical images generated by said radiographic image scanning device and said non-radiographic image scanning device, wherein said medical patient information database is accessible by said computer;a medical implant database for storing dimensional information for at least one medical implant, wherein said medical implant database is accessible by said computer; andwherein said software program is executable by said computer to overlay and align a plurality of 3-dimensional images at said display, ...

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Номер записи: 84
04-07-2013 дата публикации

Systems and Methods for Assessing the Effectiveness of a Therapy Including a Drug Regimen Using an Implantable Medical Device

Номер: US20130172774A1
Автор: Brett M. Wingeier, Felice Sun, Martha J. Morrell, Tara L. Crowder, Thomas Tcheng
Принадлежит: NeuroPace Inc

Systems and methods rely on feedback from an active medical device or devices (e.g., neurostimulator coupled to sensing and stimulation elements such as electrodes) to assess the effectiveness of a patient's drug regimen. Such reliance may include analyzing characteristics in physiological data acquired by the medical device(s), for example, in the form of responses evoked from the patient by electrical stimulation waveforms. Systems and methods further involved adjusting one or more parameters according to which a combination therapy consisting of at least a drug regimen and an electrical stimulation therapy are delivered to a patient, in an effort to optimize the therapeutic effect of the combination. The adjustments may be automatically by one or more implanted or external hosts working together or alone, and/or with the input of a physician.

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Номер записи: 85
18-07-2013 дата публикации

Medical image diagnosis apparatus and computer-readable medium

Номер: US20130184537A1
Автор: Megumu Fukuda, Nobuyuki Konuma
Принадлежит: Toshiba Corp, Toshiba Medical Systems Corp

A medical image diagnosis apparatus according to an embodiment includes: an image data generating unit, an abnormal region detecting unit, a warning data generating unit, and a display unit. The image data generating unit generates clinical-diagnosis image data on the basis of taken image data obtained in a main image taking mode. The image data generating unit also generates failure-diagnosis image data on the basis of taken image data obtained in a failure diagnosis mode. The abnormal region detecting unit detects, from the failure-diagnosis image data, an abnormal region caused by a failure in the apparatus, by comparing the failure-diagnosis image data with reference image data acquired in advance. The warning data generating unit generates warning data on the basis of a result of the abnormal region detection. The display unit displays the clinical-diagnosis image data to which the warning data is appended.

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Номер записи: 86
18-07-2013 дата публикации

Magnetic Resonance Imaging Compatible Positron Emission Tomography Detector

Номер: US20130184559A1
Автор: Corbeil James L., Schmand Matthias J., Zhang Nan
Принадлежит: SIEMENS MEDICAL SOLUTIONS USA, INC.

A compact magnetic resonance imaging compatible positron emission tomography detector. The detector has integrated mechanical and electrical subcomponents. The detector uses a cooling channel which does not interfere with magnetic resonance imaging. The layout and selection of electrical subcomponents of the detector, along with a magnetic resonance compatible cooling strategy, enables the detector to function in a magnetic resonance imaging environment. 1. A magnetic resonance imaging compatible positron emission tomography detector comprising:at least one flex region;a cooling channel coupled to the at least one flex region;at least one printed circuit board array coupled to the cooling channel;at least one avalanche photodiode array coupled to the at least one printed circuit board array; andat least one lutetium oxyorthosilicate array coupled to the avalanche photodiode array.2. The detector as recited in claim 1 , wherein a thickness of the detector is smaller than 45 millimeters.3. The detector as recited in claim 1 , wherein a thickness of the detector is smaller than 42 millimeters.4. The detector as recited in claim 1 , wherein the at least one avalanche photodiode array is housed within a thermally optimized seat.5. The detector as recited in claim 4 , wherein the thermally optimized seat comprises a thermally conductive polymer.6. The detector as recited in claim 1 , further comprising a radiation shield.7. The detector as recited in claim 6 , wherein the radiation shield comprises a tungsten polymer.8. The detector as recited in claim 1 , wherein the cooling channel comprises copper and at least one ceramic material.9. The detector as recited in claim 8 , wherein a thickness of the cooling channel is smaller than five millimeters.10. The detector as recited in claim 1 , wherein the cooling channel is configured so as to not interfere with a magnetic resonance signal.11. The detector as recited in claim 1 , wherein the detector is a cassette detector. ...

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Номер записи: 87
25-07-2013 дата публикации

SYSTEMS, PROCESSES AND SOFTWARE ARRANGEMENTS FOR EVALUATING INFORMATION ASSOCIATED WITH AN ANATOMICAL STRUCTURE BY AN OPTICAL COHERENCE RANGING TECHNIQUE

Номер: US20130188850A1
Автор: Bouma Brett Eugene, Evans John A., Tearney Guillermo J.
Принадлежит: The General Hospital Corporation

Software systems, arrangements and processes for evaluating an image associated with at least one portion of an anatomical structure are provided. For example, first information associated with the at least one portion of the anatomical structure second information associated with the at least one portion of the anatomical structure can be received. Third information can be generated by determining a relationship between the first information and the second information. Further, the image can be evaluated using a predetermined pathological scoring criteria and the third information. 1. A process for evaluating at least one image associated with at least one portion of an anatomical structure , comprising:receiving first information associated with the at least one portion of the anatomical structure;receiving second information associated with the at least one portion of the anatomical structure;with a processing device, generating third information by determining a relationship between the first information and the second information; andevaluating the at least one image using a predetermined pathological scoring criteria and the third information.2. The process according to claim 1 , wherein at least one of the first information or the second information is associated with a light remitted from the at least one portion.3. The process according to claim 2 , wherein the light is reflected from the at least one portion.4. The process according to claim 2 , wherein the light is fluorescence.5. The process according to claim 1 , wherein the at least one portion is provided in a living subject.6. The process according to claim 1 , wherein the at least one portion of the anatomical structure is situated on a microscope slide.7. The process according to claim 6 , wherein the slide is stained with at least one of Hematoxylin and Eosin claim 6 , Masson's Trichrome claim 6 , Papanicolaou's stain claim 6 , Diff-Qwik claim 6 , or Periodic Acid Shiff.8. The process according to ...

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Номер записи: 88
25-07-2013 дата публикации

Flexible tether with integrated sensors for dynamic instrument tracking

Номер: US20130188855A1
Автор: Adrien Emmanuel Desjardins, Christopher Stephen Hall, Gert Wim &#39;T Hooft, Guy Shechter, Raymond Chan, Robert Manzke
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS NV

A system and method are provided for tracking a functional part of an instrument during an interventional procedure and displaying dynamic imaging corresponding to a functional part of the instrument. The system comprises: at least one instrument; a system for acquiring anatomical images relevant to guiding the instrument; a tether connected to the imaging system at a fixed end and connected to the instrument at a distal end, the tether comprising at least one longitudinal optical fiber with a plurality of optical shape sensors; an optical console that interrogates the sensors and detects reflected light; and a processor that calculates local curvature at each sensor location to determine the three-dimensional shape of the tether and determines the location and orientation of the instrument relative to the images using the local curvatures of the tether and the location of the fixed end of the tether.

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Номер записи: 89
25-07-2013 дата публикации

SYSTEMS AND METHODS FOR REAL-TIME TARGET VALIDATION FOR IMAGE-GUIDED RADIATION THERAPY

Номер: US20130188856A1
Автор: Adler, Clayton James E., JR. John Rodenbeck, Shi Jianing
Принадлежит: Varian Medical Systems, Inc.

Systems and methods for real-time target validation during radiation treatment therapy based on real-time target displacement and radiation dosimetry measurements. 1. A method of validating a target during a radiation therapy treatment session , comprising:generating X-ray images of a target volume using the therapeutic radiation beam;comparing the X-ray images of the target volume with corresponding previously generated reference images of a 3D scan of the target volume to determine similarity measures between the X-ray images and the reference images; anddetermining a displacement of the target volume based on the similarity measures,wherein when the displacement exceeds a threshold displacement a feedback signal is generated.2. The method of claim 1 , further comprising reconstructing a 3D target volume using the X-ray images claim 1 , and determining a displacement of the target volume based on the similarity measure and/or the reconstructed 3D target volume.3. The method of claim 1 , further comprising determining in real-time a radiation dose delivered to the target volume.4. The method of claim 3 , wherein the determining displacement includes determining displacement of the target volume based on the similarity measure claim 3 , and/or the radiation dose delivered to the target volume.5. The method of claim 1 , wherein the comparing includes comparing X-ray trajectory and energy information contained in the X-ray images with corresponding trajectory and energy information contained in the reference images.6. The method of claim 5 , wherein the similarity measures include a measure of trajectory and energy similarity between the X-ray images and the corresponding reference images.7. The method of claim 1 , wherein the reference images are synthetic digitally reconstructed radiographs (DRRs).8. The method of claim 7 , wherein the DRRs are generated by simulating projections of the X-rays at a target volume at different isocenters of radiation and different ...

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Номер записи: 90
25-07-2013 дата публикации

METHODS AND COMPOSITIONS FOR OBJECTIVELY CHARACTERIZING MEDICAL IMAGES

Номер: US20130190605A1
Автор: Annapragada Ananth, Starosolski Zbigniew
Принадлежит:

Methods and compositions are provided for objectively characterizing a pathological lesion in a patient. The method comprises: introducing into the patient a contrast enhancing agent; subjecting the patient to at least one of magnetic resonance imaging and computed tomography to obtain an image; and applying a 3-D autocorrelation function to a subdomain of interest of the image to obtain at least one 3-D autocorrelation spectrum. The method may further comprise comparing the at least one 3-D autocorrelation spectrum to a pre-existing 3-D autocorrelation spectrum that is characteristic for the pathological lesion. In one example, the methods and compositions may be useful for identifying and objectively characterizing amyloid plaque deposits characteristic of Alzheimer's Disease. 1. A method for characterizing a pathological lesion in a patient , the method comprising:introducing into the patient a contrast enhancing agent;subjecting the patient to at least one of MRI and CT to obtain an image; andapplying a 3-D autocorrelation function to a subdomain of interest of the image to obtain at least one 3-D autocorrelation spectrum.2. The method of claim 1 , further comprising comparing the at least one 3-D autocorrelation spectrum to a pre-existing 3-D autocorrelation spectrum that is characteristic for the pathological lesion.3. The method of claim 1 , wherein the subjecting comprises subjecting the patient to MRI.4. The method of claim 3 , wherein the contrast enhancing agent comprises: a phospholipid;', 'a phospholipid that is derivatized with a polymer; and', 'cholesterol,', 'wherein the liposomes at least one of encapsulate and chelate gadolinium compounds., 'liposomes, the liposomes comprising5. The method of claim 3 , wherein the contrast enhancing agent comprises: DPPC;', 'Gd-DTPA-BSA;', 'cholesterol; and', 'mPEG2000-DSPE., 'liposomes, the liposomes comprising6. The method of claim 3 , wherein the contrast enhancing agent comprises a GdDTPA chelate derivative ...

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Номер записи: 91
01-08-2013 дата публикации

HEMOGLOBIN CONTRAST IN MAGNETO-MOTIVE OPTICAL DOPPLER TOMOGRAPHY, OPTICAL COHERENCE TOMOGRAPHY, AND ULTRASOUND IMAGING METHODS AND APPARATUS

Номер: US20130197346A1
Автор: Milner Thomas E.
Принадлежит: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

Provided herein are systems, methods, and compositions for the use of optical coherence tomography for detection of cells. 1. A method for detecting a lymphocyte , comprising: applying a first magnetic field strength to the lymphocyte , wherein the lymphocyte comprises a cellular membrane and a magnetically susceptible material; applying a second magnetic field strength to the lymphocyte , wherein the second magnetic field strength is different from the first magnetic field strength and interacts with the magnetically susceptible material to cause a change in the lymphocyte relative to interaction of the lymphocyte with the first magnetic field strength; and detecting the lymphocyte by detecting the change in the lymphocyte , wherein the change is detected using a phase sensitive frequency domain optical coherence tomographic imaging modality including a common path interferometer during the application of at least one of the first and second magnetic field strengths.2. The method of claim 1 , wherein the change is selected from the group consisting of:movement of the lymphocyte, movement of the magnetically susceptible material, a change in the cellular membrane tension level, and a change in the internal strain field of the lymphocyte.3. The method of claim 1 , wherein the phase sensitive optical coherence tomographic imaging modality comprises using a probe for transmitting and receiving light energy to and from the lymphocyte.4. The method of claim 3 , wherein the probe further comprises a magnetic source for applying at least one of the first and second magnetic field strengths to the lymphocyte.5. The method of claim 1 , wherein at least one of the first and second magnetic field strengths is applied to the lymphocyte from a magnetic source located external to the probe.6. The method of claim 1 , wherein the magnetically susceptible material is located within the lymphocyte.7. The method of claim 1 , wherein the magnetically susceptible material is targeted to ...

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Номер записи: 92
01-08-2013 дата публикации

METHOD FOR CALCULATING A VALUE OF AN ABSORPTION PARAMETER IN POSITRON EMISSION TOMOGRAPHY

Номер: US20130197349A1
Автор: Blumhagen Jan Ole, Fenchel Matthias, Ladebeck Ralf
Принадлежит:

A method is disclosed for calculating a spatially resolved value of an absorption parameter for a positron emission tomography (PET) scan of an examination object via magnetic resonance tomography (MRT). Magnetic resonance data is acquired within a first region lying within a field of view of a magnetic resonance system and within a second region bordering on the first and lying at the edge of the field of view. The method includes the spatially resolved calculation of a first value of the absorption parameter from the first MR data within the first region and of a second value from the second MR data within the second region. A three-dimensional parameter map is obtained from the first value. This parameter map is extended by the second value such that within the first region and the second region the parameter map has the value of the absorption parameter in spatially resolved form. 2. The method of claim 1 , wherein the first MR data within the second region includes greater spatial distortions than the second MR data.3. The method of claim 1 , wherein the second MR data is recorded by way of an MR recording sequence which comprises:generation of a gradient field including a nonlinearity of its spatial dependence such that, in the second region, the nonlinearity compensates for a spatial inhomogeneity of a basic magnetic field.4. The method of claim 1 , wherein the first MR data is acquired by way of a Dixon MR recording technique in which the phase angle of the magnetization in fat and water at an echo time instant is used in order to differentiate between fat and water fractions in the examination object.5. The method of claim 1 , wherein the first MR data includes a relatively higher spatial resolution than the second MR data.6. The method of claim 1 , further comprising:interpolating the second value of the absorption parameter, calculated from the second MR data, onto the spatial resolution of the first value of the absorption parameter.7. The method of ...

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Номер записи: 93
08-08-2013 дата публикации

Multi-modality compact bore imaging system

Номер: US20130204113A1
Автор: Raz Carmi
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS NV

A multi-modality imaging system ( 100 ) includes a gantry ( 101 ), including at least first and second imaging modalities ( 102, 104 ) respectively having first and second bores ( 113, 112 ) arranged with respect to each other along a z-axis, and a subject support ( 108 ) that supports a subject for scanning. The gantry is configured to alternately move to a first position at which the subject support extends into the first bore of first imaging modality for scanning an extremity of the subject and to a second position at which the subject support extends into the second bore of second imaging modality for scanning the extremity of the subject.

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Номер записи: 94
08-08-2013 дата публикации

SYSTEM AND METHOD FOR COLLECTION & USE OF MAGNETIC RESONANCE DATA & MICROWAVE DATA TO IDENTIFY BOUNDARIES OF INTEREST

Номер: US20130204118A1
Автор: Golnabi Amir H., MEANEY Paul M., PAULSEN Keith D.
Принадлежит: Dartmouth College

A system and method for detecting permittivity and conductivity boundaries within a high resolution spatial image of a material is presented. Electrical properties of a material, such as permittivity and conductivity, may assist in identification of physical properties of the material. Structural boundaries within tissue may be identified in spatial images, such as MR images. Image reconstruction algorithms may combine these structural boundaries with microwave images of the tissue to determine the permittivity and conductivity parameters within the structural boundaries. In the case of soft tissue, the microwave images may be captured simultaneously with the spatial images. The microwave images may be taken at a different time from the spatial image for rigid tissue. The method may be employed for two dimensional or three dimensional image reconstruction. 1. A method for use of spatial resolution data and microwave data to identify region boundaries of interest in soft tissue , wherein the method comprises the steps of:simultaneously gathering spatial resolution data and microwave data from the soft tissue;creating a customized mesh segmented into multiple subzones from spatial information resulting from the gathered spatial resolution data; andperforming image reconstruction using spatial information resulting from the gathered spatial resolution data and gathered microwave data.2. The method of claim 1 , further comprising the step of identifying boundaries between regions within the spatial resolution data.3. The method of claim 1 , further comprising the step of identifying regions having the same or similar dielectric properties.4. The method of claim 3 , further comprising the step of penalizing a variation within the regions identified to have the same or similar dielectric properties.5. The method of claim 4 , further comprising the step of restricting smoothing across a boundary shared by a first region within the gathered spatial resolution data ...

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Номер записи: 95
08-08-2013 дата публикации

NANOPARTICLE-GUIDED RADIOTHERAPY

Номер: US20130204121A1
Автор: Albrechtsen Morten, Andresen Thomas Lars
Принадлежит:

The present invention relates to a method and nano-sized particles for image guided radiotherapy (IGRT) of a target tissue. More specifically, the invention relates to nano-sized particles comprising X-ray-imaging contrast agents in solid form with the ability to block x-rays, allowing for simultaneous or integrated external beam radiotherapy and imaging, e.g., using computed tomography (CT). 1. A composition comprising nano-sized particles comprising a solid form of a compound detectable by X-ray imaging for use in image-guided radiotherapy of a target tissue in an individual , the target tissue comprising undesirably growing cells.2. The composition according to claim 1 , wherein the image-guided radiotherapy comprises:a) administering said composition to said individual;b) recording X-ray images of the target tissue to obtain a definition of the target tissue; andc) using the definition of the target tissue obtained in b) to direct radiotherapy to the target tissue;wherein b) and c) are performed sequentially or simultaneously.3. The composition according to claim 1 , wherein the nano-sized particles have a half-life in circulation of at least 1 hour.4. The composition according to claim 1 , wherein the nano-sized particles have a number average diameter of 10 to 150 nm.5. The composition according to claim 1 , wherein the nano-sized particles are selected from the group consisting of liposomes claim 1 , polymersomes claim 1 , dendrimers claim 1 , water-soluble cross-linked polymers claim 1 , hydrocolloids claim 1 , micelles claim 1 , coated metal particles claim 1 , and coated particles wherein the core is a solid salt.6. The composition according to claim 1 , wherein the nano-sized particles are liposomes.7. The composition according to claim 1 , wherein the nano-sized particles are coated particles where the core comprises a solid metal and/or a solid metal salt.8. The composition according to claim 1 , wherein the nano-sized particles comprise a shell or ...

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Номер записи: 96
15-08-2013 дата публикации

Automated quantification of intravascular embolization success

Номер: US20130208957A1
Автор: Matthias Bertram, Ming De Lin, Steffen Gunther WIESNER
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS NV

The present invention relates to a device ( 2 ) for automatically quantifying intravascular embolization success, comprising a registration unit ( 4 ) adapted for registering a first image and a second image, a segmentation unit ( 6 ) adapted for segmenting a tissue of interest in the first image and in the second image and an evaluation unit ( 8 ) for evaluating a deviation of perfusion of the tissue of interest by comparing the first image and the second image. The first image is obtained before an interventional treatment, whereas the second image is obtained after such a treatment. Evaluating may comprise comparing the segments of the first and the second images and thus providing a quantitative measure for a perfusion deviation of the tissue, e.g. the perfusion deviation of a tumorous tissue before and after an embolization treatment.

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Номер записи: 97
15-08-2013 дата публикации

IMAGE PROCESSING APPARATUS

Номер: US20130208958A1
Автор: TOMOTO Yusuke
Принадлежит: OLYMPUS MEDICAL SYSTEMS CORP.

An image processing apparatus includes: an image input section via which a medical image picked up of a mucous surface of a living body is inputted; a setting section that sets a region of interest as a first region and a second region including a unit region in the medical image; a feature value calculating section that calculates a first feature value relating to a shape of the region of interest based on pixel values of the region of interest and a region in a periphery thereof and a second feature value relating to a shape of the unit region based on pixel values of the unit region and a region in a periphery thereof; and an matching section that matches the region of interest with a predetermined shape based on distributions of the first feature value and the second feature value calculated by the feature value calculating section. 1. An image processing apparatus comprising:an image input section via which a medical image picked up of a mucous surface of a living body, the medical image including a plurality of pixels, is inputted;a setting section that sets a region of interest as a first region including one or more pixels in the medical image and sets a second region including a unit region including the one or more pixels that are different from those of the region of interest in the medical image;a feature value calculating section that calculates a first feature value relating to a shape of the region of interest based on a pixel value of the region of interest set by the setting section and a pixel value of a region in a periphery of the region of interest, and calculates a second feature value relating to a shape of the unit region based on a pixel value of the unit region and a pixel value of a region in a periphery of the unit region; anda matching section that matches the region of interest with a predetermined shape based on distributions of the first feature value and the second feature value calculated by the feature value calculating section.2. ...

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Номер записи: 98
15-08-2013 дата публикации

MEDICAL IMAGE PROCESSING APPARATUS, AN X-RAY CT SCANNER, AND A MEDICAL IMAGE PROCESSING PROGRAM

Номер: US20130208970A1
Автор: Fujisawa Yasuko
Принадлежит:

A medical image processing apparatus to accurately identify malignant transformations of probable tumors. The medical image processing apparatus including a specifying mechanism and first, second, and third computing mechanisms. The specifying mechanism specifies a probable tumor from medical image data upon receiving the medical image data obtained by imaging a subject by a single medical imaging apparatus. The first computing mechanism calculates morphological information indicating morphological characteristics of a specified probable disease based on this medical image data. The second computing mechanism calculates functional information of the specified probable disease based on this medical image data. The third computing mechanism calculates amount of progress characteristics indicating the extent of the probable disease based on the morphological information and functional information. 1. A medical image processing apparatus comprising:a specifying part configured to specify a probable disease from medical image data upon receiving medical image data obtained by imaging a subject by means of a single medical imaging apparatus;a first computing part configured to calculate morphological information indicating morphological characteristics of the specified probable disease based on the medical image data;a second computing part configured to calculate functional information of the specified probable disease based on the medical image data; anda third computing part configured to calculate an amount of progress characteristics of indicating a progressing extent of the probable disease based on the morphological information and the functional information.2. The medical image processing apparatus according to claim 1 , wherein;the medical image data comprises a plurality of contrast enhanced image data obtained by imaging the subject in which a contrast agent has been injected by means of the medical imaging apparatus, andthe second computing part is configured ...

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Номер записи: 99
15-08-2013 дата публикации

Arthroscopic Surgical Planning and Execution with 3D Imaging

Номер: US20130211232A1
Автор: Armand Mehran, Hungerford Marc, Lepisto Jyri, Murphy Ryan J., Otake Yoshito
Принадлежит: THE JOHNS HOPKINS UNIVERSITY

A method includes obtaining a first three-dimensional (3-D) image of a bone structure, generating a surgical plan based on the first 3-D image and registering the surgical plan to the bone structure to generate a registered surgical plan by obtaining a first 2-D real-time video image of the bone structure and a second 3-D image of the bone structure, and correlating structures from the first 2-D real-time video image and the second 3-D image with the surgical plan. The method also includes obtaining a second 2-D real-time image of the bone structure and overlaying the registered surgical plan onto the second 2-D real-time video image. 1. A method comprising:obtaining a first three-dimensional (3-D) image of a bone structure;generating a surgical plan based on the first 3-D image; obtaining a first 2-D real-time video image of the bone structure and a second 3-D image of the bone structure, and', 'correlating structures from the first 2-D real-time video image and the second 3-D image with the surgical plan;, 'registering the surgical plan to the bone structure to generate a registered surgical plan byobtaining a second 2-D real-time image of the bone structure; andoverlaying the registered surgical plan onto the second 2-D real-time video image.2. The method of claim 1 , wherein the three-dimensional image is generated by at least one of a magnetic resonance imaging (MRI) device and a computed tomography x-ray device.3. The method of claim 1 , wherein generating the surgical plan includes generating a three-dimensional representation of the bone structure.4. The method of claim 3 , wherein the three-dimensional representation of the bone structure includes data distinguishing a portion of the bone structure identified for removal.5. The method of claim 1 , wherein obtaining the first and second real-time images includes inserting an arthroscope into a body at a location corresponding to the bone structure.6. The method of claim 1 , wherein the second 3-D image is ...

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Номер записи: 100