СИСТЕМА И СПОСОБ УПРАВЛЕНИЯ ИЗЛУЧЕНИЕМ И ЕГО МИНИМИЗАЦИИ

Изобретение относится к медицинской технике, а именно к системе и способу управления излучением и его минимизации. Система содержит устройство генерации излучения, монитор, устройство мониторинга внимания для генерации сигнала внимания, показывающего, когда внимание оператора направлено на монитор, модуль мониторинга внимания, сконфигурированный для определения зоны фиксации оператора, модуль активации излучения для генерации задающего сигнала излучения и активации пучка излучения оператором и блок управления. Способ включает этапы работы с системой управления. Использование заявленной группы изобретений позволяет минимизировать воздействие потенциально вредного излучения на оператора и/или пациента. 2 н. и 8 з.п. ф-лы, 14 ил.

ЕМКОСТНОЕ СЧИТЫВАЮЩЕЕ УСТРОЙСТВО

Изобретение относится к емкостному считывающему устройству для считывания электрофизиологического сигнала человека. Емкостное считывающее устройство содержит емкостной датчик (2) для емкостного считывания показаний объекта (3) и корпус (4) для заключения в себя емкостного датчика (2). Корпус (4) содержит контактную сторону (6) для осуществления контакта с объектом (3) в ходе считывания, причем корпус (4) и емкостной датчик (2) приспособлены для считывания показаний объекта (3) посредством емкостного датчика (2) через контактную сторону (6) корпуса (4). Корпус (4) и емкостной датчик (2) способны отделяться друг от друга для использования емкостного датчика (2) в качестве устройства многократного применения и для использования корпуса (4) в качестве одноразового устройства. По меньшей мере один из емкостного датчика (2) и корпуса (4) содержит удерживающий элемент (7) для удерживания емкостного датчика внутри корпуса, при этом удерживающий элемент имеет выемку для фиксации емкостного датчика ...

ЭЛЕКТРОД ДЛЯ ФУНКЦИОНАЛЬНОГО КАРТИРОВАНИЯ СКРЫТЫХ КОРТИКАЛЬНЫХ ФОРМАЦИЙ (ВАРИАНТЫ)

Группа изобретений относится к медицинской технике, а именно к электродам для функционального картирования скрытых кортикальных формаций. Электрод содержит токопроводящие элементы и непроводящий корпус. Токопроводящие элементы включают рабочий контакт, провод и коннекторный контакт. Корпус содержит рабочую и нерабочую части. Рабочая часть имеет две стороны, выполнена гибкой, включает армирующий компонент и измерительную шкалу. Начало отсчета измерительной шкалы находится на дистальном конце корпуса. Нерабочая часть содержит кабель и/или рукоятку. Активная поверхность каждого рабочего контакта расположена на одной из сторон рабочей части корпуса. Форма и размеры рабочих контактов и межконтактные расстояния обеспечивают покрытие картируемых структур необходимым количеством рабочих контактов. Зазоры между внешними краями рабочих контактов и краями корпуса минимальны или отсутствуют. В другом варианте выполнения электрода начало отсчета измерительной шкалы находится на проксимальном или дистальном ...

БИОМЕДИЦИНСКАЯ ЭЛЕКТРОДНАЯ ПОДУШКА

Изобретение относится к медицинской технике. Биомедицинская электродная подушка для создания электрического контакта с биологическим объектом содержит электрод с электродным выводом, контактным элементом, электрически изолирующей удерживающей сеткой, подкладочным слоем. Контактный элемент расположен на электродном выводе. Электродный вывод выполнен с возможностью приведения в электрический контакт с биологическим объектом через контактный элемент. Удерживающая сетка покрывает контактный элемент, содержит отверстия и прикреплена к подкладочному слою. Контактный элемент выполнен с возможностью непосредственного контакта с биологическим объектом через отверстия сетки и размещен в проеме подкладочного слоя. Достигается надежный электрический контакт электродов с кожей пациента. 13 з.п. ф-лы, 9 ил.

БИОМЕДИЦИНСКИЙ ЭЛЕКТРОД

Изобретение относится к медицинской технике. Биомедицинский электрод содержит плоскую верхнюю часть, нижнюю часть и электродный материал. Плоская верхняя часть имеет отверстие. Нижняя часть имеет гибкий фланец с направленным вверх скосом, выступающий вверх головной участок и фланец, расположенный в месте перехода между головным участком и гибким фланцем. Головной участок может быть зафиксирован в отверстии верхней части посредством посадки с натягом или защелкивающего соединения. Выступающая вверх головка расположена на гибком фланце. Фланец расположен таким образом, чтобы обеспечивать упор, задающий смещение по высоте в вертикальном направлении, для создания предварительно заданного отклонения гибкого фланца, с возможностью формирования заданной силы в вертикальном направлении после того, как посадка с натягом между верхней частью и нижней частью будет завершена и плоская верхняя часть вместе с электродным материалом прижата к гибкому фланцу и остановлена фланцем в положении, при котором ...

МОБИЛЬНЫЙ ЭЛЕКТРОЭНЦЕФАЛОГРАФ

Полезная модель относится к медицинской технике и может быть использована в медицинской и научно-исследовательской практике для анализа функциональной активности мозга методом электроэнцефалографии, основанным на регистрации биопотенциалов при помощи электродов. Техническим результатом является минимизация габаритных размеров электроэнцефалографа. Мобильный электроэнцефалограф включает заключенные в единый корпус установленные последовательно и соединенные электрической связью блок усиления и фильтрации сигнала, блок обработки сигналов, блок памяти и управления. Блок памяти и управления снабжен модулем беспроводной передачи данных и слотом для записи данных на карту памяти. Он дополнительно снабжен соединенным на вход с блоком памяти и управления автономным источником питания. Устройство снабжено разъемом, установленным перед блоком усиления сигналов, соединенным с ним двусторонней связью и выполненным с возможностью подсоединения к коммутатору электродных отведений. Все перечисленные элементы ...

Способ определения индивидуальных параметров нормобарической гипероксии

Изобретение относится к медицине, к функциональной диагностике, и может быть использовано для определения индивидуальных параметров нормобарической гипероксии путем регистрации изменений биопотенциалов головного мозга. Определяют уровень биоэлектрической активности мозга по данным биспектрального индекса (БЭА) перед непосредственным проведением нормобарической гипероксии. Объемную скорость подачи кислорода (ОСПК) увеличивают на 1 л/мин каждые 15-30 минут. Определяют средний БЭА в каждом временном интервале и сравнивают его с предыдущим значением БЭА. При фиксации отрицательной динамики БЭА значение ОСПК предыдущего временного интервала принимают за целевое, с которым продолжают нормобарическую гипероксию. Способ позволяет предупредить кислородную интоксикацию при нормобарической гипероксии и повысить ее эффективность за счет БЭА. 3 пр.

СИСТЕМА И СПОСОБ УПРАВЛЕНИЯ ИЗЛУЧЕНИЕМ И ЕГО МИНИМИЗАЦИИ

... 1. Устройство излучения, содержащее:источник излучения, генерирующий пучок излучения, направляемый на объект;контроллер излучения, соединенный с источником излучения, при этом контроллер излучения содержит модуль зоны фиксации, определяющий зону фиксации оператора источника излучения, и контроллер излучения генерирует сигнал управления коллиматором частично на основании определенной зоны фиксации оператора; иколлиматор, соединенный с контроллером излучения, который основан на сигнале управления коллиматором, непрерывно фильтрует излучение, находящееся за пределами области интереса, для снижения дозы излучения от источника излучения в случае излучения, находящегося за пределами области интереса.2. Устройство по п. 1, отличающееся тем, что источник излучения содержит подвижный анод, механически перемещаемый для перемещения пучка излучения.3. Устройство по п. 2, отличающееся тем, что подвижный анод изменяет направление пучка излучения.4. Устройство по п. 1, отличающееся тем, что источник излучения ...

БИОМЕДИЦИНСКАЯ ЭЛЕКТРОДНАЯ ПОДУШКА

НАУШНИКИ С ДОПОЛНИТЕЛЬНОЙ ФУНКЦИЕЙ ДАТЧИКА ФУНКЦИОНАЛЬНОГО СОСТОЯНИЯ СЛУШАЮЩЕГО

Способ снятия аналоговых сигналов для анализа сна и бодрствования, характеризующийся использованием контактных электродов, которые размещают в контакте с ухом человека, отличающийся тем, что в качестве контактных электродов, используют наушники, которые выполняют в виде токопроводящего материала, который размещают на внешней поверхности корпуса динамиков наушников в той ее части, которая контактирует с ухом или виском человека.

ЭЛЕКТРОДНАЯ НАКЛАДКА ОДНОРАЗОВОГО ИСПОЛЬЗОВАНИЯ

... 1. Электродная накладка одноразового использования для медицинских целей, содержащая:гибкую удлиненную подложку с первой и второй поверхностями,первый адгезивный материал, нанесенный на первом адгезивном участке у первого конца первой поверхности,второй адгезивный материал, нанесенный на втором адгезивном участке у второго конца первой поверхности, инесколько электродов, помещенных на первую поверхность подложки между первым и вторым адгезивными участками с обеспечением возможностью обернуть ее вокруг части тела таким образом, чтобы электроды на первой поверхности пришли в контакт с кожей части тела, и прижать первый и второй адгезивные участки первой поверхности друг к другу с образованием стабильной конструкции, охватывающей указанную часть тела, при этомсреди электродов имеются противоэлектрод, измерительный электрод и контрольный электрод ицентры противоэлектрода и контрольного электрода находятся по разные стороны линии, расположенной параллельно длинной стороне подложки и проходящей ...

BIOMETRISCHES SENSORPAKET ZUM ANBRINGEN AN EINEM BEKLEIDUNGSSTÜCK

Hier wird ein biometrisches Sensorpaket beschrieben, insbesondere ein biometrisches Sensorpaket zum Integrieren in ein Bekleidungsstück. Außerdem werden Verfahren zum Fertigen derartiger biometrischer Sensorpakete offenbart. Ferner werden Verfahren zum Integrieren von biometrischen Sensorpaketen in Bekleidungsstücke offenbart. Die hier beschriebenen biometrischen Sensorpakete lassen sich in einfacher Weise mit derzeitigen Fertigungsverfahren für biometrische Sensoren fertigen, beispielsweise von Herstellern von Herzschlag-Überwachungsgürteln. Die hier beschriebenen biometrischen Sensorpakete lassen sich dann einfach von den gängigen Bekleidungsstückherstellern in Bekleidungsstücke einarbeiten, ohne dass irgendeine spezielle Kenntnis oder Werkzeuge bezüglich aktueller biometrischer Sensoranordnungen in den biometrischen Sensorpaketen erforderlich wären. Durch den Einsatz der hier beschriebenen biometrischen Sensorpakete lassen sich biometrische Sensoranordnungen, beispielsweise Pulsüberwacher ...

Sonde für Brainmapping

Sonde (100) für die Stimulation und Aufnahme von neuraler Aktivität des Gehirn, aufweisend: a) einen sich in axialer Richtung erstreckenden Schaft (11); b) wenigstens eine Stimulationselektrode (20); c) wenigstens eine Aufnahmeelektrode (31, 32, 33, 35).

ELEKTRISCHES STECKERSYSTEM FÜR ELEKTRODEN

Vorrichtung und Verfahren zum Detektieren eines Fahrerzustands basierend auf biometrischen Signalen des Fahrers

Eine Vorrichtung und ein Verfahren zum Detektieren von biometrischen Signalen eines Fahrers und Klassifizieren des Fahrers in einen Normalzustand oder einen Ermüdungszustand basierend auf den biometrischen Signalen sind vorgesehen. Eine derartige Vorrichtung kann aufweisen: einen biometrische-Signal-Messteil (100), der konfiguriert ist, um die biometrischen Signale einschließlich einer Blutflussrate im Gehirn des Fahrers mittels einer Elektroenzephalografie (EEG), einer Elektrokardiografie (EKG) und einer funktionellen Nahinfrarotspektroskopie (fNIRS) des Fahrers zu messen, einen biometrisches-Signal-Integrierteil (110), der konfiguriert ist, um die gemessenen biometrischen Signale zu integrieren, Charakteristiken der jeweiligen biometrischen Signale aus den gemessenen biometrischen Signalen zu extrahieren und die extrahierten Charakteristiken dann zu integrieren oder die extrahierten Charakteristiken der biometrischen Signale zu klassifizieren und dann die klassifizierten Charakteristiken ...

Verfahren zum Herstellen einer Elektrodenstruktur sowie Elektrodenstruktur für eine neuronale Schnittstelle

Bereitgestellt wird ein Verfahren zum Herstellen einer Elektrodenstruktur für eine neuronale Schnittstelle, wobei ein erstes Elektrodenmodul und wenigstens ein zweites Elektrodenmodul, vorzugsweise getrennt voneinander, hergestellt werden und wobei das zweite Elektrodenmodul auf dem ersten Elektrodenmodul angeordnet wird. Die Anordnung des zweiten Elektrodenmoduls auf dem ersten Elektrodenmodul erfolgt vorzugsweise derart, dass die Elektrodenkontaktflächen des unteren, d. h. des ersten Elektrodenmoduls nicht von Elektrodenkontaktflächen und/oder Leiterbahnen des oberen, d. h. des zweiten Elektrodenmoduls abgedeckt werden. Des Weiteren wird durch die Erfindung eine Elektrodenstruktur für neuronale Schnittstellen bereitgestellt, welche mit dem erfindungsgemäßen Verfahren herstellbar ist.

A headset

Electrode

Electrode apparatus

Probe arrays

A probe array comprises a substrate having an array of pillar probes 44, i.e. electrodes, extending in a direction orthogonal to the plane of the substrate and having a first cross-sectional area. Each probe is disposed on a pedestal 45 formed on the substrate where each pedestal has a second cross-sectional area greater than the first cross-sectional area and forms a platform from which the pillar probe extends. A plurality of channels 47 are formed between the pedestals, the channels each having a width less than the spacing between the pillar probes. The channels ensure that a supply of critical fluids can be delivered to an underside of a cellular sample into which the pillar probes penetrate. In embodiments, the pedestals and pillars may be arranged in a two-dimensional grid area.

Medical sensor

Method and apparatus for measuring biological electrical activity

Apparatus measuring biological electrical activity using a plurality of sensors, eg EMG, in contact with a human or animal. A signal injector inputs a reference signal into the body at a frequency different to that of biological electrical activities. The plurality of sensors each detect a magnitude of the reference signal and biological electrical signals. A lift detection unit receives the signals from the sensors, determining the amount of contact the sensors have with the body. A noise cancellation unit weights the signals according to their contact with the body and forms an active cancellation signal by combining the weighted sensor signals. Preferably, the noise cancellation unit removes the reference signal from the signals detected before those signals are combined to form the active cancellation signal. Preferably, the noise cancellation unit suppresses signals with lower contact quality relative to signals with better contact. Suppression of the signals may be determined using ...

Biosensing electrodes

A dual modality sensor 1 comprises a tissue contact electrode 9 and a mechanical sensor 11, overlying the electrode, configured to sense a mechanical displacement, or movement, through the electrode. The sensor may be used to reduce noise in bioelectrical signals from the tissue contact electrode by using a movement signal from the mechanical sensor to attenuate or remove motion artefact. The sensor may also be used to enhance physiological sensing by combining a bioelectrical signal from the electrode with a movement signal from the mechanical sensor to determine a physical property of the user. The mechanical sensor covering the electrode may comprise a vibration sensor, a microphone or a piezoelectric transducer. The electrode may comprise an electrically conductive layer defining a diaphragm of the mechanical sensor and may be a cutaneous electrode with a conductive bio-compatible material. The mechanical sensor may be disposed on a carrier that retains the electrode.

Implantable electronic device

DEVICE FOR REGULATION ACOUSTIC OF EVOCATIONS OF BRAIN POTENTIALS

SWIMMING ELECTRODE

EINRICHTUNG ZUR APPLIKATION VON EEG-ELEKTRODEN

ELECTRODE FOR A BIO POTENTIAL SIGNAL

MULTIMODALES SYSTEM TO THE PROOF AND AS A CHECK OF CHANGES OF THE CONDITION OF THE BRAIN

SYSTEM FOR MONITORING OR TREATMENT OF ILLNESSES OF THE NERVOUS SYSTEM

Electrodes hood

Die Erfindung betrifft eine Elektrodenhaube (1) umfassend zumindest eine Elektrodenanordnung (10) zum Anlegen an den Kopf eines Probanden (2) sowie EEGMessanordnung, - wobei jede der Elektrodenanordnungen (10) umfasst: - eine Isolierschicht (11), - zwei einander an der Isolierschicht (11) gegenüberliegende Elektroden (12, 13), nämlich eine erste, dem Kopf des Probanden (2) zugewandte Messelektrode (12) und eine dem Kopf des Probanden (2) abgewandte Referenzelektrode (13), und - einen an der Referenzelektrode (13) anliegenden und mit dieser in elektrischem Kontakt stehenden leitfähiger Körper (14), der auf der dem Kopf des Probanden (2) abgewandten Seite der Referenzelektrode (13) angeordnet ist, und - wobei die einzelnen leitfähigen Körper (14) aller Elektrodenanordnungen (10) elektrisch leitend miteinander verbunden sind.

Apparatus and method for electrical stimulation of a subject

Die Erfindung betrifft ein Verfahren und eine Vorrichtung zur Elektrostimulation eines Probanden (3) wobei eine Anzahl Elektroden (21) an das Gehirn (31) eines Probanden angelegt wird, wobei nach der Abgabe des Stimulus die an den einzelnen Elektroden (21) anliegenden Spannungen gemessen und analysiert werden, wobei im Rahmen einer Vorauswahl aufgrund dieser Analyse einzelne der Elektroden (21) für die Abgabe eines Stimulus ausgewählt werden, wobei aus den einzelnen vorausgewählten Elektroden (21) eine Elektrode (21) ausgewählt wird und mit dieser Elektrode (21) ein Stimulus auf das Gehirn (31) abgegeben wird. Erfindungsgemäß ist vorgesehen, dass die bei der Vorauswahl die Messsignale (M) verwendete Analyse die an den Elektroden (21) anliegenden Signale, insbesondere ausschließlich, auf das Vorliegen von Signalleistungen oder Signalenergien im Bereich von 60 Hz bis 1kHz, insbesondere zwischen 60 Hz und 180 Hz, untersucht werden.

SHIELDED ELECTRODE PLUG CONNECTOR

SYSTEM FOR MONITORING OR TREATMENT OF ILLNESSES OF THE NERVOUS SYSTEM

Electrode for mounting on the human skin

Elektrode zum Anbringen auf der menschlichen Haut mit einem elektrisch nichtleitenden Träger, der auf seiner der Haut abgewandter Oberseite ein vorstehendes, elektrisch leitendes Anschlusselement mit einer Anschlussstelle zum lösbaren Anschließen eines Signalleiters aufweist, wobei ein zumindest teilweise auf der gegenüberliegenden Unterseite des Trägers verlaufender Querleiter vorgesehen ist, der elektrisch mit dem Anschlusselement sowie mit einem der Haut zugewandten Kontaktmedium in Verbindung steht, wobei das Anschlusselement (5) aus einem einzigen Teil besteht, das einerseits mit dem elektrischen Querleiter (3) in Verbindung steht und andererseits die Anschlussstelle (5a) zum lösbaren Anschließen einer Signalleitung aufweist.

Electrode

Elektrode zum Anbringen auf der menschlichen Haut mit einem elektrisch nichtleitenden Träger (1), der auf seiner der Haut abgewandten Oberseite ein vorstehendes, elektrisch leitendes Anschlusselement (2) mit einer Anschlussstelle (2a) zum lösbaren Anschließen eines Signalleiters aufweist, wobei ein zumindest teilweise auf der gegenüberliegenden Unterseite des Trägers (1) angeordneter Leiter (3) vorgesehen ist, welcher elektrisch mit dem Anschlusselement (2) sowie mit einem der Haut zugewandten Kontaktmedium (4) in Verbindung steht, wobei das Anschlusselement (2) zumindest einen durch den Träger (1) reichenden Vorsprung (2b) aufweist, der an seinem Ende einen durch Verformung gebildeten, erweiterten Bereich (BZ) aufweist, wobei durch diesen verformten, erweiterten Bereich (BZ) einerseits eine elektrische Verbindung zwischen dem Leiter (3) und dem Anschlusselement (2a) und andererseits eine mechanische Befestigung des Anschlusselements (2) am Träger (1) herstellbar sind.

Electrode for mounting on the human skin

Elektrode zum Anbringen auf der menschlichen Haut mit einem elektrisch nichtleitenden Träger, der auf seiner der Haut abgewandter Oberseite ein vorstehendes, elektrisch leitendes Anschlusselement mit einer Anschlussstelle zum lösbaren Anschließen eines Signalleiters aufweist, wobei ein zumindest teilweise auf der gegenüberliegenden Unterseite des Trägers verlaufender Querleiter vorgesehen ist, der elektrisch mit dem Anschlusselement sowie mit einem der Haut zugewandten Kontaktmedium in Verbindung steht, wobei das Anschlusselement (5) aus einem einzigen Teil besteht, das einerseits mit dem elektrischen Querleiter (3) in Verbindung steht und andererseits die Anschlussstelle (5a) zum lösbaren Anschließen einer Signalleitung aufweist.

EINRICHTUNG ZUR APPLIKATION VON EEG-ELEKTRODEN

SENSOR ARRANGEMENT AND PROCEDURE FOR THE MONITORING OF PHYSIOLOGICAL PARAMETERS

VORRICHTUNG ZUM ANLEGEN VON ELEKTRODENANORDNUNGEN

The invention relates to a device comprising a number of electrode assemblies (10), which can be applied to the skin surface (4) of an animal or human being and by means of which voltages and currents can be tapped from the skin surface (4), and comprising a flexible, in particular extendable, retaining element (6) formed by a planar or film-like molded part. According to the invention, the electrode assemblies (10) comprise a main body (1) and a number of pin electrodes (2) that protrude from the main body (1) in the same direction, the electrode assemblies (10) are fastened to the retaining element (6), and the main body (1) of the respective electrode assembly (10) is connected to the retaining element (6), wherein the pin electrodes (2) of all electrode assemblies (10) protrude in the same direction.

GEFEDERTER SENSOR UND SENSORARRAY

The invention relates to a sensor (1), suitable for EEG measurements, having a sensor housing (4) and at least one transducer (2) with a transducer tip (22), wherein the transducer (2), on an underside of the sensor housing (4), protrudes partially from the sensor housing (4), and the transducer tip (22) is spring-mounted with at least one spring element (6, 61) in such a way that, when pressure is applied, the transducer tip (22) is moved from a starting position in the direction towards the sensor housing (4) and, when the pressure is removed, moves back again to the starting position, wherein an envelope (3) made of absorbent material for taking up liquid is arranged on the underside of the sensor housing (4) and surrounds the transducer (2), and, when pressure is applied to the transducer tip (22), the latter is moved into the envelope (3). In the starting position, it protrudes from the envelope (3). The invention further relates to a sensor array comprising such sensors and to a measuring ...

DEVICE AND PROCEDURE FOR THE RECOGNITION AND REMOVAL OF RADIO FREQUENCY NOISE IN BIO POTENTIAL SIGNALS

Tragbare Sendervorrichtung zum Signalisieren eines Zustands eines Benutzers

An embodiment of the invention discloses a portable transmitter device (102) containing: a sensor designed to emit a sensor signal (114); and a signaling unit (112) designed to determine, from the sensor signal, the presence of a defined state (for example an emergency or fall) of a user of the transmitter device (102). The signaling unit (112) is further designed to transmit, in the event of the presence of a predefined state, a state message (116) (for example an emergency message) to a defined receiving device (104).

ELECTRICAL PLUG SYSTEM FOR ELECTRODES

ELECTRODE ARRANGEMENT FOR THE MEASUREMENT OF ELECTRICALPHYSIOLOGICAL SIGNALS

Mobile Wearable Monitoring System

Abstract An apparatus for determining and monitoring neurological or muscular disorder, comprising of: sensors for acquiring electro-myographic (EMG) signals of a subject; wherein the EMG signals are used to determine REM stages of sleep; and wherein the EMG signals are used to determine the presence of atonia; and the EMG signals are used to determine the presence of REM sleep behavior disorder (such as Parkinson's, restless leg, leg movement syndrome, dystonia, Wilson's disease, Huntington, Alzheimer or the like) and the sensors are for determining the electroencephalographic (EEG) signals of subject, or they further comprising determining elecro-oculogram (EOG) signals or motion signals. The apparatus is also used in monitoring muscular disorder that is a Parkinson's disease's disorders. WO 2016/110804 PCT/IB2016/050042 Title: Somfit FIGURES J --- INV, Figure 1 LEFT TOP: figure presents example of a subject/patient wearable neuro sleep/fitness/health management systems comprising applied ...

Medical device for sensing and or stimulating tissue

Devices, methods and systems for transmitting signals through a device located in a blood vessel of an animal, for stimulating and/or sensing activity of media proximal to the device, wherein the media includes tissue and/or fluid. 1 of 1 ...

Neurological monitoring cable for magnetic resonance environments

An electrode system includes an electrode, a connector, and a cable with an in line radio-frequency filter module comprising resistors and inductors without any deliberately added capacitance. The resistors are arranged in an alternating series of resistors and inductors, preferably with resistors at both outer ends, and connected electrically in series. The in-line module is located at a specific location along the wire, chosen through computer modeling and real-world testing for minimum transfer of received RF energy to a patient's skin, such as between 1OOcm and 150cm from the electrode end of a 240 centimeter cable. The total resistance of the resistors plus cable, connectors and solder is 1000 ohms or less; while the total inductance is roughly 1560 nanohenries. The inductors do not include ferrite or other magnetic material and are, together with the resistors, stock components thereby simplifying manufacture and reducing cost.

Myocardial drug delivery apparatus and methods

MYOCARDIAL DRUG DELIVERY APPARATUS AND METHODS An apparatus (10) for delivery of medication to a delivery site within the body of a patient, the apparatus (10) comprising: a controller communicatively coupled to a sensor and a drive source of an implanted device, wherein the implanted device comprises a storage device (30) comprising a plurality of solid form medication elements (100) and a capture chamber coupled to the storage device (30), the capture chamber (80) including a housing (81) having an interior volume for receiving one or more medication elements (100) from the storage device (30), the housing (81) including at least one porous section allowing tissue fluids to seep in and out of the chamber at a site of implant of the implanted device, wherein the controller is configured to (i) receive one or more signals from the sensor, (ii) detect a specific event in the patient based on the one or more signals from the sensor, and (iii) in response to detection of the special event, ...

Wire-Free Monitoring Device for Acquiring, Processing and Transmitting Physiological Signals

Abstract A wireless physiological device for acquiring and processing physiological signals, the device comprising: a sensor patch comprising a plurality of electrodes, configured to be in contact with a skin surface of a patient, to generate a plurality of physiological signals of the patient; and at least one wire-free module, embedded in the sensor patch, comprising: an auto-orientation module to detect an orientation of the sensor patch on the patient using a plurality of sensors; a processing module to: select one or more bio-potential signals from the plurality of physiological signals generated by the sensor patch based on the detected orientation of the sensor patch; and process the one or more bio-potential signals selected to obtain one or more processed signals; a detection module to detect the one or more processed signals as a predefined physiological data; and a transmission module to transmit the detected physiological data to a mobile device. WO 2016/181321 PCT/IB2016/052694 ...

System and method for transit access using EEG sensors

A wearable electronic device comprising an electroencephalography (EEG) sensor for enabling access to a transit system. The device may also include a device transmitter configured to wirelessly transmit a request signal to a gate receiver. The device may further include a device processor configured to receive an EEG signal from the EEG sensor, analyze the EEG signal to determine that the transit user is attempting to enter the transit system through a particular gate, generate the request signal identifying the transit user and indicating that the transit user is attempting to enter the transit system through the particular gate, and wirelessly transmit, using the device transmitter, the request signal to the gate receiver. The EEG signal may be based at least in part on the transit user viewing a visual stimuli displayed by the particular gate.

Physiological monitoring garment

Electrode array

A disposable electrode array 100, 200 including a flexible member 106, 206 in which a plurality of electrodes 102, 202 are disposed, having a shape adapted to contact the forehead skin surface on a human patient. A pair of ear loops 104, 204 coupled to the disposable electrode array 100, 200 secure the disposable electrode array 100, 200 about the patient's ears, with the flexible member 106, 206 disposed across the patient's bow, retaining the electrodes 102, 202 against the skin surface. Additional electrodes 102, 202 are disposed in proximity to the ear loops 104, 204 and are configured to contact the skin surface behind the patient's ears. An auditory stimulus delivery element 116, 216 is coupled with each of the ear loops 104, 204, and positioned to seat in proximity to the patient's ear canal for the delivery of auditory stimulus. Electrical conductors associated with the electrodes 102, 202 and the stimulus delivery elements 116, 216 are routed within the flexible member 106, 206 ...

Packaging for medical pads and electrodes

Method and apparatus for the detection of aberrant neural-electric activity

Embodiments provide an apparatus and method for detection of aberrant neural-electric activity (ANEA) in the brain causing an epileptic seizure or other neurologic condition. One embodiment provides an apparatus for detection of ANEA comprising an introducer having at least one lumen. The introducer is introduced into brain tissue through an opening in the skull. A reference electrode is positioned at an introducer distal portion. A plurality of electrode members are advanceable within the at least one lumen with each member having an insulated portion and an exposed distal portion. The members have a non-deployed state in the introducer and a deployed state when outwardly advanced out of the introducer. In the deployed state, the members are substantially orthogonal to each other with the exposed distal portions defining a detection volume capable of determining an electric field vector produced by the ANEA and the direction of a foci of the ANEA.

Electrode system with rigid-flex circuit

An electrode system comprises a flexible circuit substrate and a plurality of electrode modules. The flexible circuit substrate comprises a flexible material and traces supported by the flexible material. The flexible circuit substrate extends through at least two of the electrode modules such that the electrode modules encompass portions of the flexible circuit substrate. Each electrode module comprises at least one rigid circuit member configured to process ERPs of a test subject. The rigid circuit members are layered against the flexible circuit substrate such that the rigid circuit members and the flexible circuit substrate together form a rigid-flex circuit. A sensor may be removably disposed through a substantially central opening defined by each electrode module.

Two part EEG monitor with databus and method of communicating between the parts

A personal wearable EEG monitor with a base part (1) having signal processing means (23),an electrode part (2) with at least two electrodes (11, 12) for measuring an EEG signal of a person. The electrode part(2)comprises means for converting the EEG signal into a digital signal. The EEG monitor comprises a databus for transferring data between the base part (1) and the electrode part (2) and for providing power from one part to the other. The databus is adapted for application of two electrical wires.

ELECTROENCEPHALOGRAPH SENSOR FOR USE WITH MAGNETIC RESONANCE IMAGING AND METHODS USING SUCH ARRANGEMENTS

Modular physiologic monitoring systems, kits, and methods

Systems, devices, methods, and kits for monitoring one or more physiologic and/or physical signals from a subject are disclosed. A system including patches and corresponding modules for wirelessly monitoring physiologic and/or physical signals is disclosed. A service system for managing the collection of physiologic data from a customer is disclosed. An isolating patch for providing a barrier between a handheld monitoring device with a plurality of contact pads and a subject is disclosed.

Systems and methods for brain activity interpretation

The present invention provides a computer-implemented method, including: obtaining an electrical signal data representative of brain activity of a particular individual; processing the electrical signal data based upon a pre-determined predictor associated with a particular brain state, selected from a library of predictors containing a plurality of pre-determined predictors, wherein the pre-determined predictor associated with a particular brain state includes: a pre-determined representative set of wavelet packet atoms, created from the pre-determined mother wavelet, a pre-determined ordering of wavelet packet atoms, and a pre-determined set of normalization factors, wherein the processing includes: causing the electrical signal data to be deconstructed into a plurality of pre-determined deconstructed wavelet packet atoms, utilizing the pre-determined representative set of wavelet packet atoms, wherein time windows of the electrical signal data are projected onto the pre-determined representative ...

Systems, apparatuses, devices, and processes for synergistic neuro-physiological rehabilitation and/or functional development

In an embodiment a system for facilitating a subject's functional development includes sensing devices configured for sensing mind state signals; sensing devices configured for sensing body state signals; and a set of processing resources configured for generating a mind state indicator / measure, a body state indicator / measure, and a mind - body synergy indicator / measure that corresponds to an expected extent to which each of the subject's mind state and the subject's body state are cooperatively or synergistically aligned with respect to facilitating the subject's functional development. In an embodiment, the system can be configured for concurrently presenting a set of activities involving a model body part; engaging the subject in attempted imitation of the set of activities by way of attempted movement of a subject body part that is a mirror image of the model body part; presenting an indication of an expected extent to which each of the subject's mind state and body state are ...

Bioelectrode and garment

This bioelectrode is provided with: a fitting member (1106) which is composed of an electrically insulating member affixed to a surface of a garment (1100), said surface being in contact with a living organism (1000); an electrode part (1101a) which is composed of a conductive member affixed to a surface of the fitting member (1106), said surface being in contact with the living organism (1000); a connector (1102a) for connection to a bioelectrical signal measurement device, said connector (1102a) being affixed to the fitting member (1106); a wiring line (1103a) which is affixed to the fitting member (1106) and electrically connects the connector (1102a) and the electrode part (1101a) to each other; and an electrically insulating insulation member (1105) which covers a portion of the surface of the wiring line (1103a), said portion being in contact with the living organism (1000).

Localized collection of biological signals, cursor control in speech-assistance interface based on biological electrical signals and arousal detection based on biological electrical signals

The present disclosure provides a device with electrodes configured to record electrical activity that are confined to a restricted area, using recorded biological electrical signals to control cursor position in a speech-assistance interface, and using recorded biological signals to detect arousals during sleep.

Monitoring brain neural potentials

Neural activity in the brain arising from a stimulus is monitored. A stimulus is applied to a target structure of the brain and a neural measurement is obtained from at least one electrode implanted in contact with the target structure. The neural measurement is configured to capture a measure of any late response arising in the target structure, typically being a neural response arising after conclusion of an ECAP, such as in the period 1.5 – 10 ms after stimulus onset. The late response(s) can be a useful biomarker such as of therapeutic ranges of deep brain stimulation, disease progression, medication efficacy, and intra-operative changes.

Microelectrodes made from structured diamond for neural interfacing applications

A microelectrode (2) for neural interfacing applications comprises a first substrate layer (4), a second attachment layer (6), and a third layer (8) forming the active part of the electrode (2) of which the material consists of synthetic diamond made electrically conductive by doping with atoms chosen from boron, nitrogen and phosphorus atoms. The material of the third layer (8) is a textured material that comprises a compact assembly, in the form of a brush, of tubes (26) each comprising, in the form of at least one peripheral outer layer, polycrystalline diamond made electrically conductive by doping. The tubes (26) are separated from each other at the first fixed ends (28) of same and project the free ends (30) of same away from the first and second layers (4, 6) in a direction that is substantially vertical relative to the extension plane (20) of the second layer (6). A method for producing said microelectrode is also described.

Adhesive extender for medical electrode and use thereof with wearable monitor

The adhesive extenders can be used to cover and surround the medical electrode assemblies on the skin of a patient. A wearable monitor can be used to obtain electrogram data from the patient via the electrodes.

Medical device for sensing and or stimulating tissue

Devices, methods and systems for transmitting signals through a device located in a blood vessel of an animal, for stimulating and/or sensing activity of media proximal to the device, wherein the media includes tissue and/or fluid.

Medical device for sensing and or stimulating tissue

Devices, methods and systems for transmitting signals through a device located in a blood vessel of an animal, for stimulating and/or sensing activity of media proximal to the device, wherein the media includes tissue and/or fluid.

Electrode construction

Localized collection of biological signals, cursor control in speech-assistance interface based on biological electrical signals and arousal detection based on biological electrical signals

The present disclosure provides a device with electrodes configured to record electrical activity that are confined to a restricted area, using recorded biological electrical signals to control cursor position in a speech-assistance interface, and using recorded biological signals to detect arousals during sleep.

Portable eeg electrode locator headgear

Electrode connector system

Subdural electrode arrays for monitoring cortical electrical activity

Device for detecting electrical potentials in the forehead-area of a patient

DISTRIBUTED EXTERNAL AND INTERNAL WIRELESS SENSOR SYSTEMS FOR CHARACTERIZATION OF SURFACE AND SUBSURFACE BIOMEDICAL STRUCTURE AND CONDITION

Systems and methods are disclosed that use wireless coupling of energy for operation of both external and internal devices, including external sensor arrays and implantable devices. The signals conveyed may be electronic, optical, acoustic, biomechanical, and others to provide in situ sensing and monitoring of internal anatomies and implants using a wireless, biocompatible electromagnetic powered sensor systems.

AN EAR PLUG WITH SURFACE ELECTRODES

An ear plug (200) comprising a shell (206) with at least two electrodes (201 - 205) adapted for measuring brain wave signals, said electrodes (201 - 205) being connected with means for processing the measured signals, wherein the contours of the outer surface of the ear plug (200) and the electrodes (201 - 205) are individually matched to at least part of the ear canal and the concha of the user.

IMPLANTABLE ELECTRONIC DEVICES FOR DETECTING HYPOGLYCAEMIA USING EEG SIGNALS

Apparatus for capturing EEG signals comprising an implantable signal capture unit (34) connected to a proximal end of at least one implantable electrode (32) is implanted by passing a tubular guide sheath (24,26) along a subcutaneous path from an implantation site, passing the distal end of a said electrode through said guide sheath to bring said signal capture unit to said implantation site, and withdrawing said guide sheath from the electrode whilst progressively axially splitting the guide sheath to enable its removal. The signal capture unit may have a housing having at least two electrode contacts on its for capturing EEG signals in operative connection with circuitry within said housing for receiving said EEG signals and for wireless transmission thereof for reception at a location exterior to the body of the patient.

BIOMEDICAL ELECTRODE

A biomedical electrode is disclosed that includes at least first and second electrical nodes for connection to medical equipment. The biomedical electrode includes a first electrical node including a disc of conductive material having a diameter d1 and a second electrical node including a ring of conductive material. The ring is concentric with the disc and- has a diameter d2 that is larger than d1 and having a ring thickness t2 such that (4 = d1 / t2 = 6). It is further disclosed a biomedical electrode providing at least first, second, third and fourth electrical nodes for connection to medical equipment, said biomedical electrode comprising said first electrical node including a disc of conductive material having a diameter d1; said second electrical node including a first ring of conductive material, said first ring being concentric with the disc and having a radius a that is larger than d1/2; and said third electrical node including a second ring of conductive material, said second ...

SYSTEMS AND METHODS FOR UNITIZED DEVICES PLACED AT THE BEDSIDE FOR TEMPORARY RECORDING OF INTRACRANIAL EEG

The invention encompasses systems and methods that allow a clinician who is untrained in the art of electroencephalography to insert and functionalize unitized intracranial electrode arrays at the bedside that, by specific design, position ground and reference electrodes in electrically "quiet" locations to record durable, high-fidelity intracortical EEG.

DEVICES, SYSTEMS, METHODS AND ASSEMBLIES FOR MEDICAL ELECTRODES

A device including at least one medical electrode; a radio-frequency (RF) tag with an identifier (ID) that identifies the at least one medical electrode; and at least one substrate that attaches the at least one medical electrode to the RF tag.

A METHOD AND SYSTEM FOR MONITORING A LEVEL OF NON-PHARMACOLOGICALLY-INDUCED MODIFIED STATE OF CONSCIOUSNESS

A computer-implemented method for determining and/or monitoring a level of modified state of consciousness of a subject receiving a treatment session comprising modifying the state of consciousness of the subject non-pharmacologically, the method comprising the steps of: receiving response data representing a subject's response to the treatment session, wherein the response data comprises measured data comprising electroencephalogram, BEG, data, the EEG data comprising: data collected from at least one of: at least one frontal (F) EEG electrode located on the scalp anatomical region corresponding to a frontal lobe of the subject, and at least one parietal (P) EEG electrode located on the scalp anatomical region corresponding to a parietal lobe of the subject, determining from the response data, the level of modified state of consciousness of a subject of the subject.

NONINVASIVE NEURAL STIMULATION THROUGH AUDIO

First data comprising a first range of audio frequencies is received. The first range of audio frequencies corresponds to a predetermined cochlear region of a listener. Second data comprising a second range of audio frequencies is also received. Third data comprising a first modulated range of audio frequencies is acquired. The third data is acquired by modulating the first range of audio frequencies according to a stimulation protocol that is configured to provide neural stimulation of a brain of the listener. The second data and the third data are arranged to generate an audio composition from the second data and the third data.

ELECTRODE FABRICATION AND DESIGN

Disclosed are biocompatible multi-electrode devices capable of being implanted in sensitive tissue, such as the brain, and methods for fabricating such arrays. The disclosed arrays can be implanted in living biological tissue with a single needle insertion. The devices can include linear arrays with contacts along an edge, linear arrays with multiple electrodes per opening in a parylene support layer, multi-thread electrode arrays, tree-like electrode arrays, and combinations thereof. In an embodiment, a compliant electrode apparatus can comprise a biocompatible and bio-implantable compliant dielectric having a top edge defined by a top and a side along a length of the dielectric, insulated electrical traces oriented along the length of the dielectric, and electrode contacts coupled to the traces and situated on the side along the length of the dielectric, wherein an exposed portion of a respective electrode contact protrudes beyond the top edge of the dielectric.

METHOD AND APPARATUS FOR WIDE-BAND PHASE GRADIENT SIGNAL ACQUISITION

The present disclosure facilitates capture (e.g., bipolar capture) of differentially-acquired wide-band phase gradient signals (e.g., wide-band cardiac phase gradient signals, wide-band cerebral phase gradient signals) that are simultaneously sampled. Notably, the exemplified system minimizes non-linear distortions (e.g., those that can be introduced via certain filters such as phase distortions) in the acquired wide-band phase gradient signals so as to not affect the information therein that can non-deterministically affect analysis of the wide-band phase gradient signal in the phase space domain. Further, a shield drive circuit and shield-drive voltage plane may be used to facilitate low noise and low interference operation of the acquisition system.

CONNECTORS AND ENCASEMENT FOR PERSONAL HYGIENE PRODUCT WITH A DIGITAL ELEMENT

A personal hygiene product with a digital element is described. In one embodiment, a conductive sensor assembly is disposed within the personal hygiene product that includes one or more moisture sensors that generate a resistive and/or capacitive signal indicative of saturation of the personal hygiene product when in wetting contact with menstrual fluid.

SYSTEM AND METHOD FOR GENERATING VISUAL IDENTITY AND CATEGORY RECONSTRUCTION FROM ELECTROENCEPHALOGRAPHY (EEG) SIGNALS

There is provided a system and method for generating visual category reconstruction from electroencephalography (EEG) signals. The method includes: receiving scalp EEG signals; using a trained pattern classifier, determining pairwise discrimination of the EEG signals, the pattern classifier trained using a training set comprising EEG signals associated with a subject experiencing different known visual identities; determining discriminability estimates of the pairwise discrimination of the EEG signals by constructing a confusability matrix; generating a multidimensional visual representational space; determining visual features for each dimension of the visual representational space by determining weighted sums of image stimulus properties; identifying subspaces determined to be relevant for reconstruction; and reconstructing the visual appearance of a reconstruction target using estimated coordinates of the target and a summed linear combination of the visual features proportional with ...

BIOSIGNAL DETECTION GARMENT

The purpose of the present invention is to provide a biosignal detection garment which can detect a biosignal continuously and steadily for a long period without giving a wearer a discomfort feeling. The biosignal detection garment according to the present invention is provided with a half-top-type or brassiere-type garment main body part, an under belt which has a fastening tool capable of controlling the size of a chest measurement and is arranged below the garment main body part, at least two electrodes each made from electrically conductive fibers, a connector for attaching a measurement device for detecting a biosignal, and a wiring part for connecting the electrodes to the connector in an electrically conductive manner, said biosignal detection garment being characterized in that the electrodes, the connector and the wiring part are arranged on the under belt, the length of the garment main body part as measured from the top of a shoulder part of the garment main body part to the ...

APPARATUS AND METHODS FOR PREDICTING THERAPY OUTCOME

Apparatus and methods are described for use with electrophysiological signal detecting electrodes (14), and a transcranial magnetic stimulation device (10). A computer processor (16) drives the transcranial stimulation device to apply one or more pulses of transcranial magnetic stimulation to a subject. Within a given time period of applying one of the one or more pulses of transcranial magnetic stimulation to the subject, the computer processor detects an electrophysiological signal of the subject, using the electrophysiological signal detecting electrodes (14). At least partially in response thereto, the computer processor predicts an outcome of treating the subject for a neuropsychiatric condition, using a given therapy, and generates an output on an output device (18) in response to the predicted outcome. Other applications are also described.

DEVICE FOR ACQUIRING BRAIN ACTIVITY SIGNALS

La présente invention concerne un dispositif d'acquisition (10) destiné à être positionné sur la tête d'un utilisateur (12) pour réaliser un encéphalogramme. Le dispositif comprend au moins une électrode d'acquisition (32, 34, 33) configurée pour être positionnée au contact de la tête de l'utilisateur (12) au niveau d'au moins une quelconque des positions du système international 10/20 de manière à acquérir au moins un signal d'activité cérébrale représentatif des ondes cérébrales de l'utilisateur (12) et au moins un premier (36, 38, 40) et un deuxième (36, 38, 40) moyens d'ajustement de la position de l'électrode d'acquisition (32, 34)suivant un premier et un deuxième plans, respectivement. Les premier et deuxième plans sont différents et choisis parmi les plans transversal (Pt), et sagittal (Ps) de la tête de l'utilisateur (12). Les premier (36, 38, 40) et deuxième (36, 38, 40) moyens d'ajustement de la position de l'électrode d'acquisition (32, 34, 33) sont actionnables indépendamment ...

RESTRUCTURING NEURAL PATHWAYS IN THE BRAIN WITH A COMBINATION OF TRANSCRANIAL THERAPIES

Brain dysfunction can be treated by restructuring neural pathways in the brain. A desired area in the brain to form a new neural pathway is selected. The area receives a sequential combination of (1) transcranial photobiomodulation therapy (PBMT) including a series of pulses having a frequency matched to a target brain wave and (2) another transcranial stimulation (e.g., transcranial direct current electrical stimulation and/or transcranial magnetic stimulation). The different stimulation mechanisms ensure that neuroplasticity occurs to restructure a neural pathway that is dysfunctional in nature to a new neural pathway that conducts normally.

AN IMPLANTABLE ELECTRODE DEVICE AND A METHOD FOR MANUFACTURING THEREOF

The present invention relates to an implantable electrode device comprising a carrier made of a polymer material, wherein the carrier is flexible and electrically isolating, at least one measurement electrode formed by an electrically conducting pad located on the carrier, wherein the electrically conducting pad has a contact surface, at least one electrically conducting trace, and at least one electrically conducting terminal, wherein the trace electrically connects the measurement electrode and the terminal. Implantable electrode devices of this type are not suitable to remain implantable over a long time. In order to provide an implantable electrode device which may remain in a patient's body the present invention suggest to further develop the implantable electrode such that the implantable electrode device further comprises a barrier layer enclosing the carrier by covering all surfaces thereof, wherein the contact surface of the conducting pad is exposed to an outside environment, ...

EEG MONITOR

An EEG monitor (1) comprising electrodes (17) adapted for capturing EEG signals and a signal processing part (11) which is adapted for analyzing and classifying the EEG signals captured. The signal processing part (11) is adapted for identifying electrical signals captured by the electrodes (17) that are derived from muscular activity related to the process of chewing.

SYSTEM AND METHOD FOR CHARACTERISING THE SLEEP OF AN INDIVIDUAL

Système et procédé de caractérisation du sommeil d'un individu Système de caractérisation du sommeil d'un individu, le système de caractérisation comprenant : - un dispositif de mesure adapté pour mesurer un signal d'activité cérébrale représentatif des ondes cérébrales, - une unité centrale électronique adaptée pour : identifier, dans une plage de fréquences de 9 à 16 Hz, une plage réduite de fuseaux de sommeil propre à l'individu, la plage réduite de fuseaux de sommeil comprenant les fréquences d'ondes cérébrales de l'individu endormi présentant une amplitude supérieure à 15 µV et une durée comprise entre 0,5 seconde et 2 secondes, comparer au moins un paramètre du signal d'activité cérébrale de l'individu éveillé dans la plage de fréquences correspondant à la plage réduite de fuseaux de sommeil à un seuil, - une interface de communication reliée à l'unité centrale et adaptée pour émettre un signal d'avertissement perceptible par l'individu lorsque le paramètre du signal d'activité cérébrale ...

METHOD FOR ASSESSING BRAIN FUNCTION AND PORTABLE AUTOMATIC BRAIN FUNCTION ASSESSMENT APPARATUS

An apparatus for determining the neurological state of a subject, comprising: a set of electrodes configured to be placed on the subject to collect brain electrical signals; a processor; a memory operatively coupled to the processor, wherein the memory stores one or more operating instructions; and an input-output interface having at least one channel operatively coupled to the processor, wherein the input-output interface is configured to receive brain electrical signals through the set of electrodes; and the processor is configured to utilize the one or more operating instructions to perform one or more operations on the signals received through the input-output interface, wherein the one or more operations comprise: de-noising the received signals; extracting features from the de-noised signals; classifying the extracted features; and determining a neurological state of the subject based on the classification, wherein determining the neurological state comprises the steps of: determining ...

PORTABLE BRAIN ACTIVITY SENSING PLATFORM FOR ASSESSMENT OF VISUAL FIELD DEFICITS

Methods, systems, and devices are disclosed for monitoring electrical signals of the brain. In one aspect, a system for monitoring electrical brain activity associated with visual field of a user includes a sensor unit to acquire electroencephalogram (EEG) signals including a plurality of EEG sensors attached to a casing attachable to the head of a user, a visual display unit attachable to the head of the user over the user's eyes to present visual stimuli, in which the visual stimuli is configured to evoke multifocal steady-state visual- evoked potentials (mfSSVEP) in the EEG signals exhibited by the user acquired by the sensor unit, and a data processing unit in communication with the sensor unit and the visual display unit to analyze the acquired EEG signals and produce an assessment of the user's visual field, in which the assessment indicates if there is a presence of visual field defects in the user's visual field.

MODULAR PHYSIOLOGIC MONITORING SYSTEMS, KITS, AND METHODS

Systems, devices, methods, and kits for monitoring one or more physiologic and/or physical signals from a subject are disclosed. A system including patches and corresponding modules for wirelessly monitoring physiologic and/or physical signals is disclosed. A service system for managing the collection of physiologic data from a customer is disclosed. An isolating patch for providing a barrier between a handheld monitoring device with a plurality of contact pads and a subject is disclosed.

SYSTEMS AND METHODS FOR DIAGNOSIS OF DEPRESSION AND OTHER MEDICAL CONDITIONS

According to some aspects, one or more systems and methods for the diagnosis of a medical condition, such as depression, based on an analysis of sleep information. In some embodiments, the diagnostic system includes at least one recorder for recording sleep information about a patient, and at least one analyzer adapted to analyze the sleep information and determine whether the patient is experiencing the medical condition.

SYSTEMS AND METHODS FOR PROVIDING A WAKING MECHANISM

An EEG monitor with sensors placed to detect signals and analyze the signals to determine if a frequency below 12 Hz, and more particularly between 3 Hz and 8 Hz, called theta waves, are present. Theta waves are generated when the brain is entering a drowsy or sleep mode. The sensors detect brain wave signals and transmit the signals to a microprocessor which analyzes the signals and determines the brain waves being detected. The brain waves are continuously monitored and the data is continuously transmitted to a microprocessor. If brain waves are detected in the predetermined range of between 3Hz and 8 Hz the microprocessor activates a stimulus, to wake up the person wearing the device. The stimulus may be visual, auditory or tactile, such as an actuator, a phone call or any other stimulus ...

Сухой активный электрод для нейрокомпьютерного интерфейса

Полезная модель относится к медицинской технике, в частности к устройствам для снятия информации о мозговой деятельности или функциональном состоянии мозга человека при исследованиях методами электроэнцефалографии для последующего использования полученных данных в области нейрокомпьютерного интерфейса. Обеспечивает повышение качества сигнала электрической мозговой активности при проведении электроэнцефалографии неинвазивным методом без использования дополнительной электропроводящей контактной среды. Устройство включает электропроводящий токосъемник 1, который имеет внешние выступы 2 и контактный разъем 3. Контактный разъем 3 выполнен с обеспечением возможности его механического размещения в ответной части 4 контактного разъема 3. Контактный разъем 3 и его ответная часть выполнены с фиксацией от случайного выпадения, например, в виде соединения «кнопка для одежды». Электрод содержит корпус 5 и электронный модуль 6. Электронный модуль 6 размещен в корпусе 5. Ответная часть 4 контактного разъема 3 вмонтирована в электронный модуль 6. Электронный модуль 6 включает защитный резистор 7, соединенный с операционным усилителем 8 и аналоговым ключом 9. Аналоговый ключ 9 выполнен с обеспечением возможности приема внешнего сигнала управления, 9 з.п. ф-лы, 4 ил. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 182 738 U1 (51) МПК A61B 5/0478 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ (52) СПК A61B 5/0478 (2006.01) (21)(22) Заявка: 2018108624, 12.03.2018 (24) Дата начала отсчета срока действия патента: (73) Патентообладатель(и): Общество с ограниченной ответственностью "Нейроботикс Трейдинг" (RU) Дата регистрации: 29.08.2018 4967038 A, 30.10.1990. KR 20050072965 A, 13.07.2005. JP 2010264174 A, 25.11.2010. EP 3066981 A1, 14.09.2016. US 9861746 B2, 09.01.2018. RU 2479252 C2, 20.04.2013. (45) Опубликовано: 29.08.2018 Бюл. № 25 1 8 2 7 3 8 R U (54) Сухой активный электрод для нейрокомпьютерного интерфейса (57) Реферат: Полезная модель ...

Garment to facilitate electrode placement for intraoperative monitoring

A garment is provided with an electrode and indicia to facilitate placement of the garment. The indicia is used to orient the garment such that the electrode is placed in precise orientation with respect to a stimulation site to facilitate intraoperative monitoring during surgical procedures.

System and method for dynamically configurable deep brain stimulation

A DBS system and method for predicting future neurological activity in a subject and administering a corrective electrical stimulation signal to prevent anticipated pathological neuronal activity. The DBS system includes an implantable electrode configured to both record neuronal activity from a target brain area in a subject and administer the corrective electric stimulation signal to the target area. The DBS system also includes a controller configured to determine the characteristics of the corrective electrical stimulation signal based on point process models of healthy and pathological neuronal activity in the target area.

Correlating Frequency Signatures To Cognitive Processes

Determining an intended action based on one more brain signal frequencies includes establishing communication with one or more electrodes for sensing brain signals of a subject, and acquiring the brain signals via the electrodes while the subject performs at least one cognitive task, wherein the acquired brain signals having a plurality of frequencies associated therewith. A physiologic change at one or more of the plurality of frequencies may then be identified from the acquired brain signals, and the one or more of the plurality of frequencies are associated with the cognitive task.

Automated detection of sleep and waking states

Determining low power frequency range information from spectral data. Raw signal data can be adjusted to increase dynamic range for power within low power frequency ranges as compared to higher-power frequency ranges to determine adjusted source data valuable for acquiring low power frequency range information. Low power frequency range information can be used in the analysis of a variety of raw signal data. For example, low power frequency range information within electroencephalography data for a subject from a period of sleep can be used to determine sleep states. Similarly, automated full-frequency spectral electroencephalography signal analysis can be useful for customized analysis including assessing sleep quality, detecting pathological conditions, and determining the effect of medication on sleep states.

Field deployable concussion assessment device

A device and method for assessment of traumatic brain injury (TBI) is described. The device is configured to acquire brain electrical signals from a patient's forehead using one or more neurological electrodes. The acquired brain electrical activity data is subjected to artifact rejection and feature extraction, and a subset of features are then combined in at least one classifier function. The classifier functions statistically place a patient in one of four categories related to the extent of brain dysfunction: 1) normal brain electrical activity; 2) abnormal brain electrical activity consistent with non-structural injury with less severe manifestations of functional brain injury; 3) abnormal brain electrical activity consistent with non-structural injury with more severe manifestations of functional brain injury; and 4) abnormal brain electrical activity consistent with structural brain injury.

Capacitive sensing apparatus

The invention relates to a capacitive sensing apparatus for sensing an object, wherein the capacitive sensing apparatus comprises a capacitive sensor ( 2 ) for capacitively sensing the object ( 3 ) and an enclosure ( 4 ) for enclosing the capacitive sensor ( 2 ). The enclosure ( 4 ) comprises a contact side ( 6 ) for contacting the object ( 3 ) during sensing, wherein the enclosure ( 4 ) and the capacitive sensor ( 2 ) are adapted for sensing the object ( 3 ) by the capacitive sensor ( 2 ) through the contact side ( 6 ) of the enclosure ( 4 ). The enclosure ( 4 ) and the capacitive sensor ( 2 ) are separable from each other for using the capacitive sensor ( 2 ) as a reusable device and for using the enclosure ( 4 ) as a disposable device. This allows capacitively sensing an object with a new, uncontaminated enclosure ( 4 ) and a reused capacitive sensor ( 2 ) and, thus, under improved hygienic conditions.

Devices and methods for tissue modulation and monitoring

A tissue stimulating device has an elongate member, a proximal annular stimulating region and a distal annular stimulating region. Each of the annular stimulating regions circumscribe the elongate member, and each has a plurality of independently energizable electrodes that deliver current into tissue. Adjacent electrodes in the annular stimulating regions are separated from one another by an insulating member. The annular stimulating regions are axially separated from one another by a gap. An internal electrical connector electrically couples a first electrode in the proximal annular stimulating region with a first electrode in the distal annular stimulating region. The first internal electrical connector is disposed within the elongate member, and extends across the gap between annular stimulating regions. A recording electrode is disposed in the gap and is adapted to record local tissue potentials from the tissue.

Lead wire for connecting to tab electrode

A disposable tab electrode has core elements that include an adhesive conductive laminate layer and a logo sticker layer with a penetrating hole for contacting a sensor electrode. A protecting film is put around both ends of the core elements. As a result, the disposable tab electrode can be made inexpensively, stored hygienically for a long time and used easily. A lead wire for connecting to the tab electrode has a projection on one end of a sensor electrode that is adhered onto the conductive laminate layer of the disposable tab electrode. The projection is fixed to the lead wire body by a fixing member. As a result, expensive Ag-AgCl electrode sensors can be used repeatedly. The lead wire can have a nipper self-contained or integrated with the lead wire body to prevent the lead wire from separating from the disposable tab electrode during use.

Apparatus and method for monitoring, analyzing, and utilizing brainwave and biologic data at transition points along the neurochromometric sequence whereby a stimulus presented to the central nervous system results in cognition and volitional action

Apparatus and method for monitoring, analyzing, and utilizing brainwave and biologic data at transition points along the neurochromometric sequence whereby a stimulus is presented to the central nervous system results in cognition and volitional action.

Dry gel-conductive scaffold sensor

A dry gel-conductive sensor. In embodiments, the sensor comprises a scaffold structure which comprises a structure and a covering. A conductive material, which is both ionically and electronically conductive, may be dispersed within the structure. According to an embodiment, the covering comprises openings which allow conductive material through the covering to contact the skin of a subject. The covering may additionally or alternatively comprise brush-like features configured to penetrate through hair.

Electrode Applicator

An applicator for applying an electrode to a patient, and a system for recording of the electroencephalographic potential, the evoked potential, and the ground and reference potentials in electroenceophalographic and evoked potential measurements, is disclosed herein. The applicator includes a main body and a plunger unit.

Bio-signal detection electrode and bio-signal detection apparatus

Provided is a bio-signal detection electrode including: an electrode section made of a gel including an electrolytic solution; and a support section configured to support the electrode section with respect to an accessory, the electrode section adhering to the support section.

Method for Determining Locations of Implanted Electrodes with Medical Images

A method for accurate localization and visualization of implanted electrodes, such as implanted intracranial electrodes, is provided. More particularly, a realistic representation of intracranial electrode positions on patient-specific post-implantation MRI brain renderings is obtained. The resulting computer models provide an accurate depiction of electrode locations on three-dimensional brain renderings that are suitable for use in surgical planning of resection boundaries around, for example, epileptic zones. Electrodes placed inter-hemispherically are also visible with this method. In addition, a method for creating electrode “shadows” cast upon the brain model surface is provided. These electrode shadows are useful for estimating cortical areas sampled by iEEG and for locating electrodes that may straddle sulci and contact two adjacent cortical gyri.

Audio headset with bio-signal sensors

An audio headset with bio-signal sensors is provided. In some embodiments, an audio headset that includes one or more electroencephalography (EEG) sensors is provided.

Biomedical electrode system and method for detecting localized electrical signals and providing electrical stimulation

A biomedical electrode is disclosed that includes at least first and second electrical nodes for connection to medical equipment. The biomedical electrode includes a first electrical node including a disc of conductive material having a diameter d 1 , and a second electrical node including a ring of conductive material. The ring is concentric with the disc and has a diameter d 2 that is larger than d 1 and having a ring thickness t 2 such that (4≦d 1 /t 2 ≦6).

Biosignal processing apparatus, electroencephalograph, and biosignal processing method

A biosignal processing apparatus includes a signal acquisition unit and a determination unit. The signal acquisition unit is configured to acquire an output signal of an electrode that is placed on a biological surface. The determination unit is connected to the signal acquisition unit to determine, based on first frequency characteristics being frequency characteristics of the output signal, whether the electrode is in a first state in which the electrode is electrically connected to a measurement site of the biological surface or in a second state in which the electrode is electrically disconnected to the measurement site.

Portable brainwave measuring and controlling system

The present invention relates to a portable brainwave measuring method, which measures a weak brainwave signal detected from a human scalp through a noninvasive method to measure a degree of concentration through an analysis and process of the detected brainwave signal, and a control method enabled for short distance control of an electronic device or remote monitoring through the internet, by using the brainwave signal. An acceleration sensor is put on the head of a user, and a brainwave detecting means put on the head of a user to detect a brainwave and the acceleration sensor that outputs an acceleration value of three axes including XYZ axes as a signal of predetermined data are used to detect movement of the head, to thereby control the direction and speed of a brainwave-related device. In more detail, after a signal outputted from the brainwave detecting means is converted into a wireless signal and transmitted, a value of the wireless signal is inputted to a receiving unit of a display device and is expressed numerically. By setting the value inputted to the display device, a portable brainwave measuring device provides accurate device control. A control system is characterized in that a signal according to the slope direction of the head is detected and analyzed, and then numerically expressed by using 6 brainwave signals such as a delta wave (δ), theta wave (θ), alpha wave (α), SMR wave, beta wave (β) and gamma wave (σ), which are measured through the portable brainwave measuring device and the acceleration sensor put on the head. A wireless system, including a short distance wireless module for transmitting/receiving the wireless signal, includes a wireless receiving module, a signal analyzing unit, and a control output unit. Additionally, the wireless system is connected to a PC or controls a short/long distance external device.

Method And System For Detecting And Removing EEG Artifacts

A method and system for detecting and removing EEG artifacts is disclosed herein. Each source of a plurality of sources for an EEG signal is separated for a selected artifact type. Each source of the plurality of sources is reconstituted into a recorded montage and an optimal reference montage for recognizing the selected artifact type of each source. The sources with artifacts are removed and the remaining sources are reconstituted into a filtered montage for the EEG signal.

Hybrid multielectrode arrays

A method of forming a multielectrode array includes forming an alignment plate having at least two openings, forming an array bottom plate having at least two openings corresponding to the at least two openings of the alignment plate, temporarily fixing the array bottom plate to the alignment plate, inserting one or more probes or array sub-assemblies into the at least two openings, fixing the probes or array sub-assemblies to the array bottom plate, and removing the array bottom plate from the alignment plate to form a multielectrode array.

Device features and design elements for long-term adhesion

An electronic device for long-term adhesion to a mammal includes a housing with an electronic component. The electronic device may include a first wing and a second wing, each being integrally formed with the housing. An electrode is positioned on a bottom surface of each of the wings, the electrodes electrically connected to the electronic component. An adhesive layer is provided for adhesion to a surface of the mammal. The adhesive layer may cover a portion of the bottom surfaces of the wings but generally does not cover the electrode or a bottom surface of the housing. A method of applying an electronic device to a mammal includes removing first and second adhesive covers from first and second wings of the electronic device to expose an electrode and an adhesive coated on a bottom surface of each wing.

System And Method For Optode And Electrode Positioning Cap For Electroencephalography, Diffuse Optical Imaging, and Functional Neuroimaging

An electroencephalographic electrode and optode positioning device has the form of a cap suitable for placement on a subject's head. The cap has semirigid telescopic structures that stiffen it to provide accurate electrode and optode spacing, and stability during subject activity. The cap is intended for use in functional neuroimaging and, although its materials are compatible with fMRI, is usable without fMRI to permit study of physically as well as mentally active subjects.

EEG Hair Band

The present invention relates to hair band EEGs. More particularly, the present invention relates to hair bands.

Radiolucent Electrode Assembly

A lightweight, disposable and substantially radiolucent electrode or sensor assembly for that universally connects to separate, non-integrated electrodes or sensors for the monitoring of the physiological parameters of a live subject wherein the electrode assembly is comprised of one or more radiolucent electrical connectors for connecting the electrode assembly to the sensors. The present invention also discloses a method of positioning the electrode assembly on a patient whose physiological signs are being monitored such that access to the patient's chest is substantially unimpeded so as not to obstruct the electromagnetic imaging of the patient's chest, the application of defibrillation paddles or surgical procedures that require access to the chest area.

Holder set and brain function measuring device using same

This holder set is provided with: an optical bioinstrumentation holder which has at least two probe mounting units into which are inserted light-transmitting probes which irradiate light from the tip, or light-receiving probes which receive light from the tip, and which is mounted on the subject's head; and a electroencephalograph holder which has at least one electrode mounting unit into which an EEG electrode is inserted which detects the potential difference with a reference electrode. This optical bioinstrumentation holder is provided with a linear trunk unit extending in a first direction, and at least two linear branches extending in a second direction different from the first direction, and the electroencephalograph holder is provided with a linear trunk unit extending in a first direction, and at least one linear branch extending in the direction opposite to said second direction.

Information processing apparatus, program, and biosignal measurement set

An information processing apparatus includes a retaining unit, an image acquisition unit, an image processor, a comparator, and an image generator. The retaining unit is configured to retain a defined attachment position being an attachment position of a biological detection sensor with respect to a body site of a user, the defined attachment position being defined in advance. The image acquisition unit is configured to acquire a capture image captured by an imaging unit. The image processor is configured to extract, from the capture image, a body shape of the user. The comparator is configured to compare the body shape with the defined attachment position. The image generator is configured to generate, based on a comparison result by the comparator, a display image to be displayed on a display unit.

System and method for quantifying or imaging pain using electrophysiological measurements

A method for computing a quantitative metric indicative of pain experienced by a subject using an electrophysiological signal detection system is provided. Electrophysiological data are acquired from a subject with the electrophysiological signal detection system. Modulations in the acquired electrophysiological data that are associated with pain experienced by the subject during the acquisition of the electrophysiological data are identified. A quantitative metric indicative of the pain experienced by the subject is computed by processing the identified modulations in the acquired electrophysiological data.

Method and system for on-line decision making support

A method for on-line decision making support, which includes sensing biological signals of a subject upon detection of a decision making process during a performance of a task, and recording biological activity of the subject. Upon completing the decision making process, the recorded biological activity is released to a data processing system for analysis, which compares the recorded biological activity with a profile model for the subject and calculates a confident value for the recorded biological activity against the profile model for the subject. If the confident value does not meet a predefined threshold, a post-processing procedure is performed, wherein the predefined threshold represents a desired performance of the subject on the task.

Evaluation of the quality of electrode contact with a skin surface

An instrument that utilizes body contact electrodes evaluates the quality of the connections made between the electrodes and the body. An electrode contact quality evaluation circuit performs the quality evaluation, such as by determining contact impedances for the electrodes. The corresponding contact quality of each electrode is conveyed to the user.

Dry electrodes

Dry electrodes are electrodes for attachment to human skin without skin preparation or the use of electrolyte gels. The electrode includes a substrate, electrically conductive particles with at least one point, in contact with the substrate, a supporting layer that envelopes the electrically conductive particles with points that protrude from the supporting layer, and an electrical connector. Some electrodes have an electrically conductive substrate, other electrodes have an electrically conductive supporting layer.

Line-contact dry electrode

A line-contact dry electrode comprises a conductive electrode base and at least one conductive contact member extending from the conductive electrode base. The conductive contact member includes a plurality of elastic conductive branches arranged intermittently to form a comb-like electrode able to comb and push away the testee's hair and contact the testee's skin.

Line-contact dry electrode

A line-contact dry electrode comprises a conductive electrode base and at least one conductive contact member extending from the conductive electrode base. The conductive contact member includes a plurality of elastic conductive branches arranged intermittently to form a comb-like electrode able to comb and push away the testee's hair and contact the testee's skin.

System and Method for High Density Electrode Management

Systems, devices and methods for advanced electrode management in neurological monitoring applications include receiving sockets configured to receive connectors having groups of electrodes. The physician is not required to manually map each electrode with its corresponding input channel. Electrodes are coupled to the corresponding input channels in groups through connectors having a unique identification (ID). The system is configured to read the unique ID of each connector and establish its identity. Based on the ID, the system configures itself to automatically correlate or associate each electrode with its corresponding input channel when the connectors are first inserted into the receiving sockets, and again if the connectors are removed and re-inserted into different positions in the receiving sockets, to insure the electrodes are always mapped to the same input channels.

A system and method for treating various neurological disorders using synchronized nerve activation

A neuromodulation system for treatment of physiological disorders. The system includes one or more stimulators for stimulating one or more cranial nerves; one or more detectors configured for detecting a predetermined physiological state; and a control unit that controls nerve stimulation by the one or more stimulators so that it is synchronized with the at least one predetermined physiological state detected by the one or more detectors. A method of neuromodulating a patient for treatment of physiological disorder. The method includes the steps of detecting a predetermined physiological state and applying stimulation to one of the cranial nerves during the predetermined physiological state by one or more stimulators of a neuromodulation system.

Electrode units for sensing physiological electrical activity

Systems and apparatus for monitoring physiological electrical activity of an individual include a first electrode unit for receiving a first signal indicative of electrical activity at a first location on a body of the individual and a second electrode unit for receiving a second signal indicative of electrical activity at a second location on the body of the individual. Each of the first and second electrode units may be operated in a field-sensing mode wherein the electrode unit is placed on or in proximity to the individual's skin. The first and second electrode units comprise a capacitive sensor element, and the capacitive sensor element of each of the electrode units comprising an electrodynamic sensor which is sensitive to electromagnetic waves; and an antenna comprising an electrically conductive radiating element for receiving electromagnetic waves. The field-sensing mode can be either non-contact field-sensing mode wherein the electrode unit is placed on the individual's clothing or a contact field-sensing mode wherein the electrode unit is placed directly on the individual's skin.

Systems and Methods for Preventing Sleep Disturbance

A sleep monitoring and disturbance mitigation system may include a sleep status monitoring apparatus configured to collect real-time sleep data from a subject; to determine a sleep status based at least partially on the sleep data; and to transmit the real-time sleep data and sleep status to a remote receiving station; and a remote receiving station configured to receive the real-time sleep status data and the sleep status from the sleep status monitoring apparatus; to generate, based at least partially on the real-time sleep data and sleep status, a sleep disturbance priority and a sleep disturbance message including data indicative of the sleep status and the sleep disturbance priority; and to display the sleep disturbance priority message on a display located remotely from the sleep status monitoring apparatus. The sleep status monitoring apparatus may be configured to wirelessly transmit the real-time sleep data and sleep status. Real-time sleep data may include EEG data. 1. A sleep monitoring and disturbance mitigation system comprising:a sleep status monitoring apparatus configured to collect real-time sleep data from a subject; to determine a sleep status based at least partially on the sleep data; and to transmit the real-time sleep data and sleep status to a remote receiving station; anda remote receiving station configured to receive the real-time sleep status data and the sleep status from the sleep status monitoring apparatus; to generate, based at least partially on the real-time sleep data and sleep status, a sleep disturbance priority and a sleep disturbance message comprising data indicative of the sleep status and the sleep disturbance priority; and to display the sleep disturbance priority message on a display located remotely from the sleep status monitoring apparatus.2. The system of claim 1 , wherein the sleep status monitoring apparatus is configured to wirelessly transmit the real-time sleep data and sleep status to the remote receiving ...

Electrode

An electrode includes an electrically non-conductive support. A protruding, electrically conductive attachment element with an attachment site for the releasable attachment of a signal conductor is on an upper face of the support. A conductor is on the underside of the support, and is electrically connected to the attachment element and to a contact medium. The conductor and the contact medium are arranged on the underside of the support. An imaginary normal to the support, running through the attachment element, runs through the conductor or a recess in the conductor and through the contact medium or a recess in the contact medium. The conductor has on its surface a redox pair suitable for the depolarization of the electrode. The attachment element has a projection reaching through the support with a widened region at its end, and the conductor is arranged between the widened region and the support.

ELECTRODE FOR DETECTING BIOELECTRICAL SIGNALS

The invention relates to an electrode for detecting a bioelectrical signal, for example EEG, on a skin surface. The electrode comprises a coating comprising iridium oxide, where the coating has a nanostructured surface pattern providing for a capillary and hydrophilic effect when in use. 1. An electrode for detecting a bioelectrical signal on a skin surface , said electrode comprising{'b': '4', 'a skin contact part (),'}{'b': '2', 'a substrate () made of a metal,'}{'b': '3', 'a coating () comprising iridium oxide,'}{'b': 3', '1', '3, 'where the coating () covers at least part of the skin contact part of the electrode (), characterized in that said coating () comprises a nanostructured surface pattern.'}2. The electrode for detecting a bioelectrical signal on a skin surface according to claim 1 , wherein the electrode has a base diameter D of between 1 and 5 mm claim 1 , more preferred 1.5-3.5 mm claim 1 , even more preferred 2.0-3.0 mm claim 1 , most preferred 2.6 mm.3. The electrode for detecting a bioelectrical signal on a skin surface according to claim 2 , wherein a surface of the skin contact part of the electrode claim 2 , which surface is adapted to contact the skin of a user claim 2 , is curved with a curvature radius R of between 2 and 7 mm claim 2 , more preferred between 2.1 and 5 mm claim 2 , most preferred between 2.2 and 4 mm.42. The electrode for detecting a bioelectrical signal on a skin surface according to claim 1 , wherein the substrate () is made of titanium.53. The electrode for detecting a bioelectrical signal on a skin surface according to claim 1 , wherein the coating () comprises additives chosen from the group of tantalum claim 1 , titanium claim 1 , platinum claim 1 , and ruthenium.6. A method for manufacturing an electrode for detecting a bioelectrical signal on a skin surface claim 1 , said method comprising the steps ofproviding a substrate made from a metal,etching at least part of the substrate to prepare for coating,coating the ...

Stretchable conductor composition, paste for forming stretchable conductor, garment comprising wiring comprising stretchable conductor composition, and method for producing same

The purpose of the present invention is to provide a stretchable conductor that can be used to form a film having good repeated stretching durability, a garment-type election device that has a wire using the stretchable conductor, and a method for producing the same. Conductive particles, preferably silver particles, a predetermined quantity of a specific barium sulfate, and a flexible resin component are mixed together to obtain a stretchable conductor composition. A sheet made from the stretchable conductor composition thus obtained has a low initial conductivity, and a high conductivity retention rate when repeatedly stretched. By cutting the stretchable conductor composition into a predetermined shape and affixing the composition to fabric or the like that constitutes a garment, it is possible to achieve a garment-type device having electrical wiring with high stretchability.

Biological signal measuring equipment

To provide a biological signal measuring equipment that can perform the measurement in the same manner as the case of measuring a wave motion of a short period, even in the case of measuring the wave motion of a long period generated in a head portion. A biological signal measuring equipment used in the measurement of the biological signal in a head portion, has a jaw contact portion that comes into contact with a forehead; an occiput contact portion that comes into contact with the occiput; and a supporter that is interposed in a front and rear direction of the head portion and is supported by the head portion by using the jaw contact portion and the occiput contact portion as ends.

Deep intracranial electrode

A deep intracranial electrode which comprises a conducting wires, an electrode contact, a connector and a nonelastic sleeve is provided, one end of the conducting wires connected to the electrode contact, the other end connected to the connector; the nonelastic sleeve sheathes around the conducting wires, and one end of the nonelastic sleeve is capable of being connected to the connector, the other end connected to the fixing nut which is fixed to a skull. When the deep intracranial electrode is under a pulling force, the fixing nut may avoid the nonelastic sleeve from moving, thereby avoiding the deep intracranial electrode from being pulled out.

APPARATUS AND METHOD FOR USER INTERFACING IN DISPLAY GLASSES

A wearable apparatus for display glasses is provided. According to certain embodiments, the apparatus includes a display configured to provide a display of information that includes at least two options for selection. The apparatus further includes an electromyograph device and a processor. The electromyograph device is configured to track muscle activity of a wearer of the display glasses. The processor is configured to determine a plurality of events based on the muscle activity. The plurality of events are associated with at least one of types of the muscle activity, occurring numbers of the types of the muscle activity, or occurring time of the types of the muscle activity. One of the at least two options is identified based on the plurality of events. 1. A wearable apparatus for display glasses , comprising:a display comprising a pair of screens configured to provide a display of information to a wearer of the display glasses, the information comprising at least two options for selection;an electromyograph device configured to track muscle activity of the wearer; and determine a plurality of events associated with the wearer based on the muscle activity, the plurality of events being associated with at least one of types of the muscle activity, occurring numbers of the types of the muscle activity, or occurring time of the types of the muscle activity; and', 'identify one of the at least two options based on the plurality of events., 'a processor configured to2. The wearable apparatus of claim 1 , wherein the processor is further configured to identify the one of the at least two options based on overlapping events from the plurality of events associated with the wearer.3. The wearable apparatus of claim 1 , wherein:the muscle activity comprises eye muscle activity associated with movement of eye muscles of the wearer and facial muscle activity associated with movement of facial muscles of the wearer; and determine eye movement of the wearer based on the eye ...

Microelectrode and microelectrode array for detecting, recording, stimulating or monitoring activity of electrically excitable cells

A microelectrode or an array of microelectrodes for communicating with one or more adjacent electrically excitable cells. The microelectrode array comprises two or more microelectrodes. Each microelectrode comprises a body with a perimeter; an electrode wire that is electronically connected to the body and that is electronically connectible to an electronic system; and a ridge that extends away from the perimeter of the body for increasing a sealing-resistance value between the electrode and the one or more adjacent electrically excitable cells.

Health and Lifestyle Exploration Based User Engagement Application

A system and method for a user to select and implement a lifestyle intervention. The system and method allows the user to select a lifestyle intervention and define the parameters of the intervention. The system monitors physiological parameters of the user that are related to the lifestyle intervention.

Diagnostic Testing Headband

A diagnostic headband has an elongated body with two ends. A mechanism couples the two ends with one another. At least one first lead is coupled with the body. At least one second lead extends from the body. The leads couple with lead pads on the user. An electrical harness is coupled with the body. The electrical harness electrically couples with the at least one first and second leads.

Conductive stiffener, method of making a conductive stiffener, and conductive adhesive and encapsulation layers

A wearable device includes a flexible printed circuit board and one or more conductive stiffeners. The conductive stiffeners include a conductive surface that can be electrically or thermally connected to contact pads on the flexible printed circuit board. The wearable device can further include an adhesive layer or an encapsulation layer. The adhesive layer and the encapsulation layer can include conductive portions surrounded by non-conductive portions. The conductive portions can be aligned with the conductive stiffeners and together transmit electrical and/or thermal energy to the contact pads of the flexible printed circuit board.

Method of modulating epileptogenicity in a patient's brain

The invention relates to modulating epileptogenicity in a brain of an epileptic patient. The method according to the invention comprises the steps of: providing a virtual brain; providing a model of an epileptogenic and of a propagation zones and loading said models in the virtual brain to create a virtual epileptic brain; acquiring data of the brain of the epileptic patient; identifying, in said data, a location of at least one possible epileptogenic zone; fitting the virtual epileptic brain against the data acquired from the epileptic patient and parametrizing said at least one possible epileptogenic zone in the virtual epileptic brain as an epileptogenic zone; and simulating, within the virtual epileptic brain, the effect of a network modulation mimicking a clinical intervention of the brain of the patient.

MULTI-SENSOR BRAIN DETECTING APPARATUS

The invention concerns a multi-sensor brain detecting apparatus, the detecting apparatus being adapted to obtain two different physical values of a brain of a subject, the detecting apparatus comprising: 1. A multi-sensor brain detecting apparatus , the detecting apparatus being adapted to obtain at least two different physical values of a brain of a subject , the detecting apparatus comprising:a set of sensors comprising an ultrasound transducer adapted to produce ultrasound waves,a frame with a position with relation to the brain known with a stereotaxic precision, the frame being adapted to hold a sensor that can be positioned at a specific location by a user of the detecting apparatus without using a tool.2. The multi-sensor brain detecting apparatus according to claim 1 , wherein the position of the frame with relation to the brain is known by using an anatomical frame.3. The multi-sensor brain detecting apparatus according to claim 1 , wherein the detecting apparatus comprises a specific sensor adapted to determine the position of the frame.4. The multi-sensor brain detecting apparatus according to claim 1 , wherein two of the set of sensors adapted to measure different physical quantities.5. The multi-sensor brain detecting apparatus according to claim 1 , wherein the frame is adapted to hold compartments claim 1 , in which a sensor can be inserted by a user of the detecting apparatus without using a tool.6. The multi-sensor brain detecting apparatus according to claim 1 , wherein the frame has a polygonal shape delimited by sides claim 1 , each side having a length inferior or equal to 10 centimeters.7. The multi-sensor brain detecting apparatus according to claim 1 , wherein the set of sensors comprises three sensors claim 1 , one sensor being an ultrasound transducer claim 1 , one sensor being an accelerometer and one sensor being adapted to measure electrical signals.8. The multi-sensor brain detecting apparatus according to claim 1 , wherein one sensor ...

Personalized closed-loop pulsed transcranial stimulation system for cognitive enhancement

A system for closed-loop pulsed transcranial stimulation for cognitive enhancement. During operation, the system identifies a region of interest (ROI) in a subject's brain and then estimates ROI source activations based on the estimated source of the ROI. It is then determined if a subject is in a bad encoding state based on the ROI source activations. Finally, one or more electrodes are activated to apply a pulsed transcranial stimulation (tPS) therapy when the subject is in a bad encoding state, a predefined external event or behavior occurs, or the subject is in a consolidation state during sleep.

High-density implantable neural probes

Disclosed here are two approaches for implementing neural probes that consist of a thin, high-density Parylene C-based probe on a stainless steel shuttle. In a first approach, the high density Parylene C probe is microfabricated separately and is then affixed to a planar or curved stainless steel shuttle. In a second approach, the high-density probe is monolithically fabricated on a stainless steel shuttle by micromachining the stainless steel substrate.

ATTENTION DETECTION METHOD AND SYSTEM

This application provides a user attention detection method and system. The method includes: collecting an electroencephalogram signal of a user from an ear side by using an ear-side wearing apparatus (); when it is determined that the ear-side wearing apparatus () can collect electroencephalogram signals from both a left ear canal and a right ear canal of the user, performing differential processing on the electroencephalogram signals from the left ear canal and the right ear canal of the user to obtain an electroencephalogram signal; and detecting an attention type of the user based on the electroencephalogram signal. According to the method and the system, the electroencephalogram signals of the user can be obtained from the ear canals more conveniently and quickly, and an attention status of the user can be detected anytime and anywhere. 1. A user attention detection method , wherein the method comprises:collecting a user bioelectrical signal from an ear side of a user by using an ear-side wearing apparatus;obtaining a user electroencephalogram signal from the user bioelectrical signal; and{'claim-text': 'when the ear-side wearing apparatus comprises a plurality of ear-side signal measurement units, determining whether an impedance between two of the plurality of ear-side signal measurement units is less than a preset threshold, collecting bioelectrical signals from the two ear-side signal measurement units when the impedance between the two ear-side signal measurement units is less than the preset threshold, and obtaining the user bioelectrical signal based on a potential difference signal corresponding to the bioelectrical signals collected by the two ear-side signal measurement units.', '#text': 'obtaining an attention type of the user based on the user electroencephalogram signal and a machine learning model, wherein the collecting a user bioelectrical signal from an ear side of a user by using an ear-side wearing apparatus comprises:'}2. The method ...

INFORMATION PROCESSING CIRCUIT AND INFORMATION PROCESSING METHOD

An information processing circuit and an information processing method. The information processing circuit includes: a signal acquisition circuit and a signal processing circuit, the signal acquisition circuit is configured to acquire a plurality of initial neural signals that are different, the signal processing circuit includes a plurality of memristors and is configured to process the plurality of initial neural signals through the plurality of memristors, and the plurality of memristors includes a plurality of first memristors, the plurality of first memristors are arranged in an array to obtain a preprocessing array, the preprocessing array is configured to extract features of the plurality of initial neural signals to obtain a plurality of feature information. 1. An information processing circuit , comprising:a signal acquisition circuit which is configured to acquire a plurality of initial neural signals that are different; anda signal processing circuit which comprises a plurality of memristors and is configured to process the plurality of initial neural signals through the plurality of memristors,wherein the plurality of memristors comprises a plurality of first memristors, the plurality of first memristors are arranged in an array to obtain a preprocessing array, the preprocessing array is configured to extract features of the plurality of initial neural signals to obtain a plurality of feature information.2. The information processing circuit according to claim 1 , wherein the signal processing circuit comprises a preprocessing sub-circuit and a decoding sub-circuit;the preprocessing sub-circuit comprises the preprocessing array;the decoding sub-circuit is coupled with the preprocessing sub-circuit and configured to decode the plurality of feature information to determine a state classification corresponding to the plurality of initial neural signals.3. The information processing circuit according to claim 1 , wherein the preprocessing array comprises M ...

Apparatus and method for attaching electrodes to a patient

A method of attaching electrodes to a patient, the method comprises the steps of providing a squeezable member having a hollow interior, wherein a skin abrasive solution is in the interior, wherein the squeezable member includes a restrictive member having a restrictive opening for restricting flow of the skin abrasive solution out of the squeezable member, and a tip through which the solution leaving the restrictive member exists the squeezable member; squeezing the squeezable member; scrubbing skin portions of the scalp of the patient with the tip; and attaching electrodes to the skin portions of the patient's scalp.

Biosignal headphones

There are described headphones comprising earcups to be placed about ears of a user, with a headband linking the earcups and to be extending above a head of the user. A flexible band distinct from the headband is secured below the headband for contact with the head of the user. Removable headband sensors are embedded in the flexible band and have a portion thereof protruding downwardly from the flexible band to reach the scalp. The flexible band has a flexibility which makes the flexible band deform under the weight of the earcups to conform with the head of the user to ensure high quality contact between the headband electrodes and the scalp. There are further provided earcup electrodes on the earcups for contact with a region on or behind an ear of the user. Signals from the electrodes can be used for different purposes such as concentration monitoring and feedback.

Systems and methods to gather and analyze electroencephalographic data

Example devices are disclosed herein that include a first elongated band coupled to a first housing to be located on a first side of a head of a subject and a second housing to be located near a second side of the head of the subject, the first elongated band comprising a first set of electrodes. The example device also includes a second elongated band coupled to the first housing and to the second housing, the second elongated band comprising a second set of electrodes. In addition, the device includes a third elongated band coupled to the first housing and to the second housing, the third elongated band comprising a third set of electrodes.

Systems, methods and devices for a skull/brain interface

Systems, methods and devices are disclosed for directing and focusing signals to the brain for neuromodulation and for directing and focusing signals or other energy from the brain for measurement, heat transfer and imaging. An aperture in the skull and/or a channel device implantable in the skull can be used to facilitate direction and focusing. Treatment and diagnosis of multiple neurological conditions may be facilitated with the disclosed systems, methods and devices.

System and method for reversing the effects of paralysis

A method and system for applying therapeutic stimulation to a patient stricken with paralysis or other condition. The inventive method includes the steps of: inserting an acupuncture needle against the spine of the patient and applying an electrical potential to the needle with a signal that mimics natural neural impulses in the body. The needle is located depending on the nature of the patient's condition. In the illustrative application, the needle is inserted against the ligamentum flavum of the patient's spine at L3. In the best mode, the patient's legs are moved during the application of the electrical potential. The inventive system is adapted to minimize a notch reaction and includes an electrode inserted into a tissue of the patient and a circuit for applying an electrical potential to the electrodes with a signal that mimics natural neural impulses in the body.

Detecting fatigue based on electroencephalogram (eeg) data

In one aspect, an apparatus for detecting fatigue comprises a dry-contact electroencephalogram (EEG) electrode to measure EEG data operably coupled to at least one processor. The at least one processor is to: calculate a frequency domain representation of the EEG data, detect spectral features indicative of fatigue based on the frequency domain representation; and determine whether the brain is fatigued based on the detection. In another aspect, a method for detecting fatigue comprises receiving EEG data from dry-contact EEG electrode, calculating a frequency domain representation of the EEG data, detecting spectral features indicative of fatigue based on the frequency domain representation; and determining whether the brain is fatigued based on the detection.

Medical device for sensing and or stimulating tissue

Devices, methods and systems for transmitting signals through a device located in a blood vessel of an animal, for stimulating and/or sensing activity of media proximal to the device, wherein the media includes tissue and/or fluid.

INTEGRATED BRAIN MACHINE INTERFACE PLATFORM WITH GRAPHENE BASED ELECTRODES

This invention concerns a system for brain signal measurement and analysis using graphene based electrodes. The system is minimally invasive with small size electrodes and a stamp-size electronic processor with wireless communication and a remote computing device, enabling brain signal collection outside of clinical settings. The electrodes and electronic processor are both imprinted onto the subject's scalp using three-dimensional printers with small size electronics. After use, the electrodes and electronic processor may be washed off or removed without injuries to the subject.

SYSTEM AND METHOD FOR CONCUSSIVE IMPACT MONITORING

A system and a method for detecting mild traumatic brain injury (mTBI) includes a memory arrangement including stored brain data corresponding to electrical activity of a brain of a subject at locations in the brain during a first time period. In addition, the system includes a processor receiving the stored brain data and current brain data corresponding to electrical activity of the brain of the subject at the plurality of locations during a second time period, wherein the second time period is after the first time period. The processor generates a first set of phase synchrony measures (PSM) corresponding to frequency band-specific oscillatory phase synchrony of the stored brain data, and a second set of PSM corresponding to frequency band-specific oscillatory phase synchrony of the current brain data. The processor determines a likelihood of mTBI based on the first and second sets of PSM. The stored brain data may be a normative distribution of data of the electrical activity of the brain determined from a set of standards

DETERMINING COMPOSITE SIGNALS FROM AT LEAST THREE ELECTRODES

In some examples, a device includes at least three electrodes a first pair of electrodes and a second pair of electrodes. The device also includes circuitry configured to generate a first cardiac signal based on a first differential signal received across the first pair, generate a first brain signal based on the first differential signal received across the first pair, generate a second cardiac signal based on a second differential signal received across the second pair, and generate a second brain signal based on the second differential signal received across the second pair. The circuitry is also configured to output a composite cardiac signal based on the first cardiac signal and the second cardiac signal and to output a composite brain signal based on the first brain signal and the second brain signal.

Methods for sensing or stimulating activity of tissue

Methods for sensing or stimulating electrical activity of brain tissue from within an animal vessel by placement of an intravascular device within an animal vessel to control an external device, the intravascular device being adapted to at least one of sense and stimulate activity of brain tissue located outside the vessel proximate the intravascular device.

Portable brain activity sensing platform for assessment of visual field deficits

Methods, systems, and devices are disclosed for monitoring electrical signals of the brain. In one aspect, a system for monitoring electrical brain activity associated with visual field of a user includes a sensor unit to acquire electroencephalogram (EEG) signals including a plurality of EEG sensors attached to a casing attachable to the head of a user, a visual display unit attachable to the head of the user over the user's eyes to present visual stimuli, in which the visual stimuli is configured to evoke multifocal steady-state visual-evoked potentials (mfSSVEP) in the EEG signals exhibited by the user acquired by the sensor unit, and a data processing unit in communication with the sensor unit and the visual display unit to analyze the acquired EEG signals and produce an assessment of the user's visual field, in which the assessment indicates if there is a presence of visual field defects in the user's visual field.

MICRO-MOLDED ELECTRODES, ARRAYS, AND METHODS OF MAKING THE SAME

A method of manufacturing a micro-molded electrode having multiple individually addressable sensors along a shaft can include forming a recess in a mold substrate, depositing a structural material therein, depositing a conductive material at specific locations, providing a coating, and removing the mold substrate. A micro-molded electrode having a base tapering to at least one shaft can include an electrode substrate, multiple individually addressable sensors, and a coating. 1. A method of manufacturing a micro-molded electrode having multiple individually addressable sensors along a shaft of the micro-molded electrode , comprising:modifying a mold substrate to form a recess therein on a first surface of the mold substrate, the recess defining the perimeter of the micro-molded electrode;depositing a structural material within the recess to form the micro-molded electrode;depositing a conductive material at specific locations on the micro-molded electrode such that the conductive material forms the multiple individually addressable sensors along the shaft of each micro-molded electrode, each sensor comprising a bonding pad at a base of the micro-molded electrode electrically connected to an active site on the shaft of the micro-molded electrode via an electrically conductive trace, the micro-molded electrode having an active site on at least two sides of the micro-molded electrode;coating a top side of the micro-molded electrode and at least one trace with a coating material; andremoving the mold substrate outside the perimeter.2. The method of claim 1 , further comprising depositing a structural material within the recess after the deposition of the conductive material.3. The method of claim 1 , further comprising depositing a structural material within the recess before the deposition of the conductive material.4. The method of claim 3 , further comprising polishing the first surface of the mold substrate after deposition of the structural material.5. The method of ...

SYSTEMS AND METHODS FOR COLLECTING BIOMETRIC INFORMATION

Biometric information about a person may be collected and analyzed to gain insight into the person's physical and/or emotional conditions. The collection and analysis may be performed using a uniquely designed sensing device that includes multiple sets of sensors configured to collect EEG, EOG, EMG, EDA, and/or PPG signals from the person's head and/or facial areas. The sensing device may include a multi-layered facepad and may be coupled to a VR/AR headset and/or a scalp engagement apparatus to monitor the person's physiological and/or neural reactions to audio/visual stimuli. 1. A device configured to sense biometric signals from a user , comprising: a first layer comprising a plurality of openings and multiple sublayers;', 'a second layer comprising a circuit board, the circuit board comprising a plurality of sensors at least one of which is configured to pass through corresponding at least one of the plurality of openings to sense one or more of the biometric signals from the user;', 'a third layer comprising a compressible material configured to provide electromagnetic shielding for the second layer; and', 'a fourth layer configured to secure the first layer, the second layer, and the third layer to the device., 'a multi-layered facepad, wherein the multi-layered facepad comprises2. The device of claim 1 , wherein the plurality of sensors is configured to sense the biometric signals from one or more areas of the user's face claim 1 , the biometric signals indicating electroencephalography (EEG) information claim 1 , electrooculography (EOG) information claim 1 , electromyography (EMG) information claim 1 , and electrodermal activity (EDA) information about the user.3. The device of claim 2 , further comprising a photoplethysmography (PPG) circuit board configured to obtain PPG information about the user.4. The device of claim 3 , wherein the PPG circuit board is configured to be attached to the circuit board of the second layer.5. The device of claim 3 , ...

SYSTEMS AND METHODS FOR MEASURING NEUROTOXICITY IN A SUBJECT

The present disclosure relates to a system and method capable of capturing, processing and analyzing electroencephalography (EEG) signals, including features, patterns or signatures with relevance to diagnosis, prognosis, risk stratification or other clinically relevant interpretation, by means of a low-profile head-mounted wireless recording device that may be rapidly applied to the individual being examined. The head-mounted recording device is comprised of an array of electrode elements that contact the subject's forehead, a docking site and an acquisition device that receives, processes, and transmits the EEG data. In one embodiment, the device simultaneously collects additional data, including but not limited to accelerometer data, heart rate, sound level, light level, temperature and/or pulse oximetry. Subsequently, the data is ingested into an analytics system which is capable of identifying features, signatures or patterns that have significance for diagnosis, prognosis, risk-stratification or other medically pertinent observations, estimates or predictions. 1. An electroencephalography (EEG) detection system comprising: a plurality of sensors arranged at different locations, with each sensor configured to capture electrical signals from a portion of a body of an examinee; and', 'a data acquisition apparatus configured to process electrical signals from the sensors and wirelessly transmit said electrical signals to a receiver device, the receiver device being configured with one or more processors to receive and process data transmitted by the acquisition device; and, 'a wearable head-mounted device, comprisingone or more computer storage media to store data generated by the head-mounted device.2. The EEG detection system of claim 1 , further comprising a display device configured to present virtual content to the examinee claim 1 , examiner or other operator.3. The EEG detection system of claim 1 , wherein said data acquisition apparatus continuously ...

Eeg monitor with a housing individually fitted to a person

An EEG monitor adapted for being arranged in the ear region of a person and including a housing ( 11 ) holding a power supply ( 25 ) and an EEG signal processor ( 10 ). The EEG monitor ( 5 ) includes an EEG sensing part ( 12 ) having EEG electrodes ( 17 ). The EEG sensing part ( 12 ) is adapted for arrangement subcutaneously at the scalp or in the ear canal of the person, and the housing ( 11 ) is individually shaped to fit behind or above an ear of the person and into the cleft between a pinna and the skull of the person.

Omnidirectional Deployable Multichannel Neural Electrode System

A neural probe system having a single guide tube that is inserted into neural tissue and from which a number of neural probes can be deployed is described. Each probe is deployable into tissue along a desired trajectory. This is done by supporting the electrode array on a spring tape-type carrier that maintains axial stiffness once the neural probe has deployed out a channel in the guide tube. That way, a target neural tissue is bounded by an increased number of neural probes while minimizing trauma to surrounding body tissue.

Electrode system for electrical stimulation

A system for electrically stimulating and/or detecting bioelectrical signals of a user comprising: an array of permeable bodies configured to absorb a solution that facilitates electrical coupling with a body region of the user; a housing defining an array of protrusions conforming to the body region and comprising: an array of channels distributed across the array of protrusions, each channel at least partially surrounding a permeable body, configured to deliver the solution to the permeable body, and comprising a barrier that prevents passage of the permeable body past the barrier, and a manifold configured to distribute the solution to the array of channels; and a coupling subsystem comprising a first electrical coupling region in electrical communication with an interior of the manifold, wherein the first electrical coupling region is configured to couple to a second electrical coupling region that couples the first electrical coupling region to the electronics subsystem.

Nanomesh electrode structures and techniques for the formation thereof

Techniques and apparatus for bilayer nanomesh techniques for transparent and/or stretchable electrophysiological microelectrodes. The bilayer may include of a metal layer and a low impedance coating both in a nanomesh form. Bilayer nanomesh structures according to some embodiments may provide high transparency, great flexibility, large stretchability, while providing improved electrochemical performance compared with conventional systems. Other embodiments are described.

NEUROLOGICAL ELECTRODE SYSTEM FOR MAGNETIC RESONANCE ENVIRONMENTS

An electrode system includes an electrode, a connector, and a cable with an in- line radio-frequency filter module comprising resistors and inductors without any deliberately added capacitance. The resistors are arranged in an alternating series of resistors and inductors, preferably with resistors at both outer ends, and connected electrically in series. The in-line module is located at a specific location along the wire, chosen through computer modeling and real-world testing for minimum transfer of received RF energy to a patient's skin, such as between 100 cm and 150 cm from the electrode end of a 240 centimeter cable. The total resistance of the resistors plus cable, connectors and solder is 1000 ohms or less; while the total inductance is roughly 1560 nanohenries. The inductors do not include ferrite or other magnetic material and are, together with the resistors, stock components thereby simplifying manufacture and reducing cost. 1. A neurological electrode system for use in magnetic resonance environments , comprising:a magnetic resonance environment with a radio frequency (RF) field;an electrode for neurological monitoring;a connector configured to connect to an amplifier;a cable, having a first end and a second end, the first end in electrical connection to the electrode, the second end in electrical connection to the connector; andan inline filter module configured along the cable, the inline filter module comprises one or more resistors and one or more inductors configured in series, wherein total resistance of the one or more resistors is below 1 ohm, and the inline filter module limits heat generation in the electrode.2. The system of claim 1 , further comprising two or more inline filter modules configured along the cable.3. The system of claim 1 , further comprising an inline filter module placed between 40 to 80 millimeters along the cable from the electrode.4. The system of claim 1 , further comprising an inline filter module placed between 80 to ...

System and method to measure and monitor neurodegeneration

A system to measure and monitor neurodegeneration of a subject, which includes: an acquisition module configured to acquire electroencephalographic signals with multiple EEG channels from a subject perceptually isolated; a calculation module configured to extract at least one EEG metric representative of neurodegeneration; and an evaluation module configured to evaluate the at least one EEG metric and extract a neurodegeneration index.

Electrode system for electrical stimulation

A system for electrically stimulating a user comprising: a first housing portion defining an array of openings; an array of permeable bodies with portions exposed through the array of openings and wetted with a solution that facilitates electrical coupling between the system and a body region of the user, wherein each permeable body has a cavity at a proximal portion and a distal portion and is configured to transmit the solution to the body region of the user; a substrate region defining an array of protrusions configured to support the array of permeable bodies and composed of a conductive polymer; and a set of conductors in communication with the substrate region and including a first conductor that provides a first subset of the array of permeable bodies with a first polarity and a second conductor that provides a second subset of the array of permeable bodies with a second polarity.

Integrated wireless patch for physiological monitoring

A sensor system in accordance with the present invention comprises a plane member a plurality of electrodes within the plane member adapted to contact a human body to detect and monitor human generated voltages. The sensor can be applied to monitor a variety of applications relating to health disease progression fitness and wellness. Some of the specific applications include the monitoring of ECG EEG EMG glucose electrolytes body hydration dehydration tissue state and wounds. Various aspects of the invent aspects of the invention are shown by illustrating certain embodiments. Many other embodiments can be used to implement the invented schemes.

Microfabricated surface neurostimulation device and methods of making and using the same

Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localised and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged along an supportive backing layer. The microelectrode elements are dimensioned and shaped so as to target individual neurons, groups of neurons, and neural tissue as may be located in an animal nervous system, such as along a region of a cortex of a human brain. Beneficially, the neurological probe can be used to facilitate location of the neurological target and remain implanted for long-term monitoring and/or simulation.

Wearable Extended Reality-Based Neuroscience Analysis Systems

An illustrative system may include an extended reality system and a brain interface system configured to be concurrently worn by a user. The extended reality system may be configured to provide the user with an extended reality experience (e.g., an immersive virtual reality experience or a non-immersive augmented reality experience). The brain interface system may be configured to acquire one or more brain activity measurements while the extended reality experience is being provided to the user. 1. A system comprising: be worn by a user, and', 'provide the user with an extended reality experience; and, 'an extended reality system configured to be worn by the user concurrently with the extended reality system, and', 'acquire one or more brain activity measurements while the extended reality experience is being provided to the user., 'a brain interface system configured to2. The system of claim 1 , further comprising a remote neuroscience analysis management system communicatively coupled to one or more of the brain interface system or the extended reality system and configured to:transmit experiment data to one or more of the brain interface system or the extended reality system, the experiment data representative of a neuroscience experiment to be performed on the user using the brain interface system and the extended reality system; andreceive results data from one or more of the brain interface system or the extended reality system, the results data representative of one or more results of the neuroscience experiment.3. The system of claim 1 , further comprising a processing system configured to control a parameter of the extended reality experience based on the one or more brain activity measurements.4. The system of claim 1 , wherein the extended reality experience comprises an immersive virtual reality experience.5. The system of claim 1 , wherein the extended reality experience comprises a non-immersive augmented reality experience.6. The system of claim 1 , ...

Measurement device with electroencephalography and electrocardiography functionalities

A measurement device with electroencephalography (EEG) and electrocardiography (ECG) functionalities includes a shell and a turning structure. The shell includes a first contact and a second contact located at a first side of the shell; and a third contact. The turning structure, disposed on the shell, is utilized for adjusting the third contact to be located at the first side when the measurement device is in an EEG mode, and adjusting the third contact to be located at a second side of the shell when the measurement device his in an ECG mode, wherein the second side is substantially opposite to the first side.

Flexible neural probes

Embodiments include microelectrodes including a flexible shank and a bioabsorbable material surrounding the flexible shank. The flexible shank can include a flexible substrate, a circuit, and a plurality of sensors. Embodiments also include a methods of forming flexible active electrode arrays including depositing a flexible polymer on a substrate. The methods also include forming a plurality of sensors on the flexible polymer and attaching a silicon-based chip to the flexible shank. The methods also include coating the flexible shank in a bioabsorbable material and cutting the shank and a portion of the bioabsorbable material from the substrate.

Electric field encephalography: electric field based brain signal detection and monitoring

Systems and methods for measuring brain activity of a subject are disclosed, comprising: positioning a plurality of electric field sensors at multiple positions on the exterior of a skull of the subject; measuring one to three components of a plurality of instantaneous electric field vectors generated by a plurality of electric field sources, the electric field vectors being measured by the plurality of electric field sensors; and determining brain activity of the subject based on the measurement of the plurality of instantaneous electric field vectors.

Method And System For Detecting And Removing EEG Artifacts

A method and system for detecting and removing EEG artifacts is disclosed herein. Each source of a plurality of sources for an EEG signal is separated for a selected artifact type. Each source of the plurality of sources is reconstituted into a recorded montage and an optimal reference montage for recognizing the selected artifact type of each source. The sources with artifacts are removed and the remaining sources are reconstituted into a filtered montage for the EEG signal.

SYSTEMS AND METHODS FOR BRAIN ACTIVITY INTERPRETATION

A method includes receiving electroencephalographic (EEG) signal data recordings collected from a plurality of individuals via at least one EEG monitoring device. An optimized plurality of wavelet packet atoms is constructed based on the EEG signal data recordings and a mother wavelet. The optimized plurality of wavelet packet atoms is reordered to obtain an optimal reordered set of wavelet packet atoms. The optimal reordered set of wavelet packet atoms is normalized to obtain an optimal normalized set of wavelet packet atoms that is representative of brain activities of the plurality of individuals. A particular EEG signal data recording of a particular individual is received, which is projected onto the optimal normalized set of wavelet packet atoms to obtain an individual-specific set of projections for the particular individual on the optimal normalized set of wavelet packet atoms. A brain activity representation of the particular individual is generated based on the individual-specific set of projections. 1. A method , comprising: 'wherein the at least one electrode combination comprises a recording electrode and a reference electrode that are applied to particular points on a head of each individual from the plurality of individuals;', 'receiving, by a processor, a plurality of electroencephalographic (EEG) signal data recordings collected from a plurality of individuals via at least one electrode combination of at least one EEG monitoring device;'}constructing, by the processor, an optimized plurality of wavelet packet atoms based on the plurality of EEG signal data recordings and a mother wavelet;reordering, by the processor, the optimized plurality of wavelet packet atoms to obtain an optimal reordered set of wavelet packet atoms;normalizing, by the processor, the optimal reordered set of wavelet packet atoms to obtain an optimal normalized set of wavelet packet atoms that is representative of a plurality of brain activities of the plurality of individuals; ...

Eeg headpiece with transmission capabilities

A headpiece, acquisition device, system and method for making electroencephalography (EEG) measurements. The EEG headpiece fits, or adjusts to fit, on a person's scalp, each of a plurality of electrodes is located in the headpiece corresponding to selected respective positions on the scalp, the electrodes are electrically connected to at least one electrical transmitter, and the headpiece is attached to the scalp after the electrodes have been located in the headpiece.

Method and apparatus for wide-band phase gradient signal acquisition

The present disclosure facilitates capture (e.g., bipolar capture) of differentially-acquired wide-band phase gradient signals (e.g., wide-band cardiac phase gradient signals, wide-band cerebral phase gradient signals) that are simultaneously sampled. Notably, the exemplified system minimizes non-linear distortions (e.g., those that can be introduced via certain filters such as phase distortions) in the acquired wide-band phase gradient signals so as to not affect the information therein that can non-deterministically affect analysis of the wide-band phase gradient signal in the phase space domain. Further, a shield drive circuit and shield-drive voltage plane may be used to facilitate low noise and low interference operation of the acquisition system.

MULTIMODAL SENSORY STIMULATION

A multimodal sensory device for promoting sleep in a subject, including a first sensory delivery component, a second sensory delivery component, and a controller module. The sensory device wherein the first and second sensory delivery components are constructed and arranged for delivering a first and second sensory stimuli to the subject and the controller is constructed and arranged to deliver the first and second sensory stimuli at a synchronized frequency. A method for promoting sleep in a subject including delivering to the subject at least one sensory stimuli at a frequency of between about 1 and 60 hz.

Stimulation Probe

A stimulation probe comprises a lead having a distal end and a proximal end. The distal end of the lead has a plurality of electrodes configured to stimulate tissue. A protective tubing element extends over a portion of the lead proximate the proximal end of the lead. An advanced lead can element includes a switch matrix. The advanced lead can element is coupled to the proximal end of the lead and configured to couple the lead to an implantable pulse generator.

METHOD FOR IDENTIFICATION OF PATHOLOGICAL BRAIN ACTIVITY FROM SCALP ELECTROENCEPHALOGRAM

A computer-implemented method for detecting pathological brain activity patterns from a scalp electroencephalographic signal, the method including the steps of obtaining (A) an electroencephalographic signal as a function of multiple channels and time; identifying (C), for each channel, the zero-crossings of the electroencephalographic signal over a fixed threshold; generating a zero-crossing representation of at least a segment of the obtained electroencephalographic signal with the identified zero-crossings; obtaining (D) a reference family of real functions of time and channels from a zero-crossing statistical analysis of zero-crossing representation of pre-recorded electroencephalographic signals; calculating (E) a matching score by comparing the zero-crossing representation of a segment of the electroencephalographic signal with at least one reference function from the reference family of functions; and computing the matching score as a function of time by sliding the at least one reference function from the reference family of functions over the electroencephalographic signal. 118-. (canceled)19. A computer-implemented method for detecting brain activity patterns from a scalp electroencephalographic signal , the method comprising the steps of:a) obtaining an electroencephalographic signal as a function of multiple channels and time;b) identifying, for each channel, the zero-crossings of the electroencephalographic signal over a fixed threshold;c) generating a zero-crossing representation of at least a segment of the obtained electroencephalographic signal with the identified zero-crossings;d) obtaining a reference family of real functions of time and channels from a zero-crossing statistical analysis of zero-crossing representation of pre-recorded electroencephalographic signals;e) calculating a matching score by comparing said zero-crossing representation of a segment of the electroencephalographic signal with at least one reference function from the ...

Hearing Systems and Sensor Systems Including a Sensor Electrode and Methods for Manufacturing the Same

An exemplary hearing system that is configured to assist a user in hearing includes an in-the-ear (“ITE”) component that comprises a shell having a contoured outer shape that is customized for the user to fit at least partially within an ear canal of the user, a faceplate configured to fit within an opening provided in the shell and face out of the ear canal of the user when the shell is inserted into the ear canal of the user, a sensor electrode that is provided on an outer surface of the shell, and a conductive path that extends along the outer surface of the shell from the sensor electrode to the faceplate and that conductively connects the sensor electrode with a conductive portion of the faceplate. Corresponding methods and systems are also disclosed.

SYSTEMS AND METHODS FOR COGNITIVE HEALTH ASSESSMENT

An improved system for assessing cognitive function is described that uses tracked electrical activity of the brain of the individuals in response to a specific sequence of stimuli in generating data sets, which, for example, can be encapsulated as a data structure. The data sets can include tracked specific response types, at different times and amplitudes, including, but not limited to, event related potential signal components. Brainwave features including, event related potentials, are tracked in relation to both pre-attentive brain responses and consciously controlled attention responses. 1. A computing system for automatically generating a cognitive health assessment report utilizing data sets representative of potential cognitive activity of a patient , the computing system including at least one processor and computer readable memory , the at least one processor configured to:render on a user interface element on a display screen, or control an audio speaker to generate sounds corresponding to a set of instructions instructing the patient to actively recognize or respond to a set of repeated tones or visuals;control a brainwave tracking device coupled to the patient's head to record waveform features;present, on the user interface element or through the audio speaker, a stimulus pattern of tones or visuals having intermixed the repeated tones or visuals;record one or more P3b responses triggered by the presentation of the intermixed repeated tones or visuals; andencapsulate the one or more P3b responses into a data structure representing a working memory or cognitive workload data value that is utilized as part of the cognitive health assessment report; andautomatically generate and present, to an individual on a graphical user interface, the cognitive health assessment report generated based on the working memory or cognitive workload data value.2. The computing system of claim 1 , wherein the system is further configured to:render on the user interface ...

SYSTEM AND METHOD FOR MONITORING NEURAL SIGNALS

In accordance with one aspect of the disclosure, a method for estimating at least one oscillatory component of a patient brain state is provided. The method includes receiving electroencephalogram (BEG) data, fitting a space state model to the EEG data, the state space model comprising at least one oscillatory component, estimating at least one value of cross-frequency coupling of the EEG data based on the state space model, generating a report based on the at least one value of cross-frequency coupling, and outputting the report to at least one of a display and a memory. 1. A method for estimating at least one oscillatory component of a patient brain state , the method comprising:receiving electroencephalogram (EEG) data;fitting a space state model to the EEG data, the state space model comprising at least one oscillatory component;estimating at least one value of cross-frequency coupling of the EEG data based on the state space model;generating a report based on the at least one value of cross-frequency coupling; andoutputting the report to at least one of a display and a memory.2. The method of claim 1 , wherein the at least one value of cross-frequency coupling comprises an estimated value of phase amplitude modulation between a first wave component and a second wave component included on the state space model.3. The method of claim 8 , wherein the first wave is a slow wave component and the second wave is an alpha wave component.4. The method of claim 3 , wherein the estimated value of phase amplitude modulation is calculated based on a phase of the slow wave component and an amplitude of the alpha wave component.5. The method of claim 1 , wherein the at least one value of cross-frequency coupling comprises a correlation value between an oscillatory component included in the state space model and a band of frequencies of the EEG data.6. The method of claim 1 , wherein the fitting the state space model comprises fitting harmonic frequencies of each oscillatory ...

BIOSIGNAL MEASUREMENT APPARATUS

A biosignal measurement apparatus is used by being affixed on a living body. The apparatus includes an affixed part that is a sheet, in which a signal-acquiring section of multiple electrodes and wiring connected to each of the electrodes are formed, and which can be freely expanded, contracted and bent and is adhesive; and a substrate that is connected to the wiring and on which a signal-processing circuit for wirelessly transmitting biosignals obtained through the wiring is mounted. 1. A biosignal measurement apparatus used by being affixed on a living body , the biosignal measurement apparatus comprising:a sheet formed with a plurality of electrodes and a plurality of wirings connected to the plurality of electrodes respectively, the sheet being freely expanded, contracted and bent and being adhesive, wherein the sheet has a flexible connecting part, wherein a connector is provided on a tip of the connecting part; and wherein the plurality of electrodes are exposed on a front surface of the sheet, and', 'the sheet and the substrate are stacked so that a back surface of the sheet faces the substrate., 'a substrate connected to the plurality of wirings and equipped with a signal processing circuit for wirelessly transmitting a biosignal acquired via the plurality of wirings, wherein the substrate is connected to the sheet via the connector,'}2. The biosignal measurement apparatus according to claim 1 , whereineach of the sheet and the substrate under a state of the front surface of the sheet affixed on the living body has an outer shape in plan view of a size falling within a rectangle of 5 cm×15 cm.3. The biosignal measurement apparatus according to claim 1 , whereinthe plurality of electrodes include a reference electrode and a plurality of measurement electrodes.4. The biosignal measurement apparatus according to claim 3 , whereinthe reference electrode is attachable to and detachable from the sheet, and is affixed on the sheet.5. The biosignal measurement ...

Headgear for dry electroencephalogram sensors

A headgear for placing sensors on a subject's head includes a centerpiece; a plurality of arms attached to and radiating outward and generally downward from the centerpiece; and sensor tips attached to the dorsal ends of at least some of the arms. At least one of the plurality of arms is a lower arm that is elastic and/or spring-like. When the headgear is placed on a subject's head, the at least one lower arm is so disposed in relation to the maximum circumference of the subject's head that the at least one lower arm must be bent outward for placement of the headgear on the subject's head and thereby provide a reactive force toward the head that causes the at least one lower arm to grasp at least a portion of the head that is at and/or below the maximum circumference of the head.

VISUAL PROSTHESIS EMPLOYING VENTRICULAR OR ENDOVASCULAR NEURAL ELECTRODE ARRAYS

The present disclosure relates to a method of generating visual percepts using conformal electrode arrays. The electrode arrays can be placed into the ventricular system or cerebral venous sinuses, which function as minimally invasive techniques for precise spatial and temporal localization of electrical activity within the brain, and precise electrical stimulation of brain tissue, to diagnose and restore function in conditions caused by abnormal electrical activity in the brain. The disclosure further comprises a system for using these arrays to generate time-varying electric fields to stimulate the visual pathways of the brain, including the optic radiations and the occipital cortex, in ways that lead to visual perception. 123-. (canceled)24. A method of electrically stimulating or recording from portions of a brain that relate to vision using a ventricular electrode array within the ventricular system of a brain , the method comprising:determining a portion of optic radiations, a lateral geniculate body, or a visual cortex for electrical stimulation using the ventricular electrode array implanted into a ventricular compartment of the brain proximate to the optic radiations, lateral geniculate body, or visual cortex;accessing previously stored registration information regarding a location of the ventricular electrode array within the ventricular compartment of the brain;selecting one or more electrodes in the ventricular electrode array based on the registration information; andelectrically stimulating or recording from the optic radiations, lateral geniculate body, or visual cortex with the selected electrodes.25. The method of claim 24 , wherein the ventricular electrode array is conformal claim 24 , the method further comprising implanting the conformal ventricular electrode array configured to stimulate or record from targets comprising optic tracts claim 24 , lateral geniculate bodies claim 24 , or the visual cortex.26. The method of claim 24 , comprising ...

Drug delivery customized ear canal apparatus

The present invention is directed to a wearable system wherein elements of the system, including various sensors adapted to detect biometric and other data and/or to deliver drugs, are positioned proximal to, on or in the ear canal of a person. In embodiments of the invention, elements of the system, including drug delivery devices, are positioned on or in the ear canal for extended periods of time. For example, an element of the system may be positioned on the tympanic membrane of a user and left there overnight, for multiple days, months, or years. Because of the position and longevity of the system elements in the ear canal, the present invention has many advantages over prior wearable biometric and drug delivery devices.

Manufacturing of skin-compatible electrodes

A method of manufacturing a skin-compatible electrode (100) comprises printing a circuit pattern (P1) onto a flexible substrate (200) to form an electrically conductive pattern including an electrode pad area (301). A layer of an adhesive composition (401p) is printed in a second pattern (P2) onto the electrode pad area (301) to form an adhesive interface layer (401). The adhesive interface layer (401) is a dry film formed from the adhesive composition (401p) comprising an ionically conductive pressure sensitive adhesive composition comprising a resin (R), an ionic liquid (I), and optionally electrically conductive particles (P). A layer thickness and material of the flexible substrate, the conductive pattern, and the conductive adhesive interface have relatively low stiffness in plane of the flexible substrate (200).

METHOD AND APPARATUS FOR MEASURING BIOLOGICAL ELECTRICAL ACTIVITY

Apparatus for measuring biological electrical activity, comprising: a plurality of sensors adapted for contact with a human or animal body; a signal injector configured to inject a reference signal into the body, the reference signal having a frequency substantially different to frequencies characteristic of the biological electrical activity; a lift-detection unit configured to receive signals from the plurality of sensors and, in dependence on the magnitude of the reference signal detected by each sensor, form a measure of the degree of contact between each respective sensor and the body; and a noise calculation unit configured to form an active cancellation signal by combining the signals detected by the sensors in dependence on their respective measures of the degree of contact with the body and to cause the signal injector to inject the active cancellation signal into the body. 1. An apparatus for measuring biological electrical activity , the apparatus comprising:a plurality of sensors adapted for contact with a human or animal body;a signal injector configured to inject a reference signal into the body, the reference signal having a frequency substantially different to frequencies characteristic of the biological electrical activity;a lift-detection unit configured to receive signals from the plurality of sensors and, in dependence on the magnitude of the reference signal detected by each sensor, form a measure of the degree of contact between each respective sensor and the body; anda noise calculation unit configured to form an active cancellation signal by combining the signals detected by the sensors in dependence on their respective measures of the degree of contact with the body and to cause the signal injector to inject the active cancellation signal into the body.2. The apparatus as claimed in claim 1 , wherein the noise calculation unit is configured to form the active cancellation signal by forming a weighted average of the signals detected by the ...

ENDOVASCULAR ELECTROENCEPHALOGRAPHY (EEG) AND ELECTROCORTICOGRAPHY (ECoG) DEVICES, SYSTEMS AND METHODS

The present disclosure is directed to systems and methods for endovascular electroencephalography (EEG) and electrocorticography (ECoG) systems. In some embodiments, the disclosed systems include electrode arrays that are configured to record and/or stimulate brain tissue via placement within blood vessels of the brain. Venous and arterial EEG and ECoG electrodes, ambulatory EEG and ECoG systems, and transcutaneous access and signal control systems for general and ambulatory endovascular electroencephalography (EEG) and electrocorticography (ECoG), as well as endovascular neural stimulating electrodes are discussed. 1. An implantable medical device comprising:a linear array of electrodes configured for insertion into a blood vessel of a head or brain, the linear array comprising one or more electrodes configured to record or stimulate electrical activity in brain tissue; anda linear substrate including an electrically insulating material supporting the linear array of electrodes.2. The implantable medical device of claim 1 , wherein each of the electrodes comprises at least one of gold claim 1 , silver claim 1 , platinum claim 1 , or platinum-iridium and each of the electrodes has a diameter between about 5 to 25 microns claim 1 , or 25 to 250 microns.3. The implantable medical device of claim 1 , wherein the electrically insulating material comprises a hydrophilic polymer.4. The implantable medical device of claim 1 , wherein the plurality of electrodes are fabricated on the linear array scaffold using lithography claim 1 , 3D printing claim 1 , electroplating claim 1 , or a covalent-type bonding processes.5. The implantable medical device of claim 1 , wherein the one or more electrodes in the linear array are connected to an embedded multiplexing unit designed to function within a blood vessel.6. The implantable medical device of claim 1 , comprising:an embedded multiplexing unit configured to receive one or more of the electrodes from the plurality of electrodes ...

INTRADURAL NEURAL ELECTRODES

Described herein are systems and methods for deploying and recording electrophysiologic signals from electrode arrays located within the dura mater of the brain. The dura matter includes layers of connective tissue, or membrane, that surround the brain and spinal cord. The present disclosure relates to an endovascular electrode system deployed within the blood vessels located between layers of the dura mater, including, for example, the middle meningeal artery and its branches. 1. A medical device comprising:an amplifier and recording apparatus;an electrode array configured for insertion between layers of a dura membrane of the brain, the electrode array comprising a plurality of electrodes, each electrode of the plurality of electrodes configured to record or stimulate electrical activity in brain tissue; anda plurality of electrical traces, wherein each electrical trace is configured to connect an electrode of the electrode array to the amplifier and recording apparatus.2. The medical device of claim 1 , wherein the plurality of electrical traces are separately insulated.3. The medical device of claim 1 , wherein each of the plurality of electrical traces bundle to form a composite wire having a diameter between 6 and 35 thousandths of an inch.4. The medical device of claim 1 , wherein the plurality of electrical traces bundle to form a composite wire having a length of approximately 10 and 30 centimeters.5. The medical device of claim 1 , wherein a subset of the electrical traces among the plurality of electrical traces comprises different lengths.6. The medical device of claim 1 , wherein the diameter for the plurality of electrical traces decreases along the distal end of the plurality of electrical traces.7. The medical device of claim 1 , wherein the amplifier and recording apparatus comprises an embedded multiplexing unit having an analog-to-digital converter.8. The medical device of claim 1 , comprising:a wired connector configured to receive one or more ...

Differential amplifier and electrode for measuring a biopotential

A differential amplifier is described that provides a high common mode rejection ration (CMRR) without requiring the use of precisely matched components. One variation employs a method of noise reduction to increase the SNR of the device. The differential amplifier may be used in an apparatus for measuring biopotentials of a patient, such as an electrode for measuring brain activity. The electrodes can communicate the measured biopotentials with a remote system for further processing, while providing electrical isolation to the patient.

TRANSCRANIAL STIMULATION DEVICE AND METHOD BASED ON ELECTROPHYSIOLOGICAL TESTING

The present method and system provides a neuromodulation therapy including receiving a plurality of input data relating to a patient, the input data including brain value measurements and body value measurements. The method and system includes analyzing the input data in reference to reference data generated based on machine learning operations associated with existing patient data and reference database data. Based thereon, the method and system includes electronically determining, a brain malady and a severity value for the patient and electronically generating a treatment protocol for the patient, the treatment protocol includes transcranial stimulation parameters. Therein, the method and system includes applying a transcranial stimulation using the transcranial stimulation parameters based on the treatment protocol. 1. A neuromodulation therapy method comprising:receiving brain value measurements and body value measurements relating to a patient;electronically analyzing the brain value measurements and body value measurements relative to reference data generated based on machine learning operations associated with existing patient data and reference database data;based thereon, electronically determining, using at least one processing device, a brain malady and a severity value, for the patient; andelectronically generating a treatment protocol for the patient based at least on the brain malady and the severity value, wherein the treatment protocol includes a voltage strength level, a duration, and position factors for transcranial sensors providing neurostimulation to the patient.2. The method of further comprising:applying a transcranial stimulation to the patient based on the treatment protocol.3. The method of further comprising:after applying the transcranial stimulation to the patient, acquiring secondary brain value measurements and secondary body value measurements;electronically analyzing the secondary brain value measurements and secondary body value ...